PAGER3: A Pathways, Annotated-lists and Gene signatures Electronic Repository Version 3

Query: Abnormal endocrine morphology

Result Filters

Size of PAGs

Min

Max

Species

Data Source

PAGs related to the disease: 538 PAGs

PAG ID	PAG Type	PAG Name	Size	Pubmed Reference	Organism	Data source	cohension

The M-type PAG-PAG relationships

Network Visualization

PAG_A	PAG_A_SIZE	PAG_B	PAG_B_SIZE	Overlap	Similarity score	LOGCDF

The R-type PAG-PAG relationships

Network Visualization

PAG_A	PAG_B	Total	PAG_A_OUT	PAG_B_IN	A regulate B	LOGCDF

X + S-NED (more detail) 1 NA Homo sapiens

GOA TAX028334 GO:0061155 biological process pulmonary artery endothelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from the pulmon (more detail) 1 NA Homo sapiens

GOA TAX021557 GO:0032448 molecular function DNA hairpin binding Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms (more detail) 1 NA Homo sapiens

GOA TAX021242 GO:0031945 biological process positive regulation of glucocorticoid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 1 NA Homo sapiens

GOA TAX025638 GO:0046554 molecular function malate dehydrogenase (NADP+) activity Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+. (more detail) 1 NA Homo sapiens

GOA TAX021964 GO:0033080 biological process immature T cell proliferation in thymus The expansion of an immature T cell population by cell division in the thymus. (more detail) 1 NA Homo sapiens

GOA TAX027534 GO:0055020 biological process positive regulation of cardiac muscle fiber development Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle f (more detail) 1 NA Homo sapiens

GOA GEX167077 Endometriosis A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with en (more detail) 1 20601957 Homo sapiens

GWAS Catalog TAX026169 GO:0048392 biological process intermediate mesodermal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an intermediat (more detail) 1 NA Homo sapiens

GOA TAX014253 GO:0002461 biological process tolerance induction dependent upon immune response Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell (more detail) 1 NA Homo sapiens

GOA TAX014254 GO:0002465 biological process peripheral tolerance induction Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-asso (more detail) 1 NA Homo sapiens

GOA TAX020161 GO:0022018 biological process lateral ganglionic eminence cell proliferation The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion (more detail) 1 NA Homo sapiens

GOA TAX033751 GO:1905032 biological process negative regulation of membrane repolarization during cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization (more detail) 1 NA Homo sapiens

GOA TAX033464 GO:1904464 biological process regulation of matrix metallopeptidase secretion Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion. (more detail) 1 NA Homo sapiens

GOA MOX011589 Genes associated with Computational Drug Signature CHEMBL599223 Genes associated with Computational Drug Signature CHEMBL599223, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX011647 Genes associated with Computational Drug Signature CHEMBL611680 Genes associated with Computational Drug Signature CHEMBL611680, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX015983 Genes associated with Computational Drug Signature [3 (1H Imidazol 1 ylmethyl)phenyl]methanol Genes associated with Computational Drug Signature [3-(1H-Imidazol-1-ylmethyl)phenyl]methanol, curat (more detail) 1 25990557 Homo sapiens

DSigDB IEI006802 Protein protein interactors of human gene KIAA1328 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIAA1328 (SwissProt (more detail) 1 17535438 Homo sapiens

I2D NAX005178 CACNA1D (more detail) 1 NA Homo sapiens

Genome Data NAX000872 CYP11B1 (more detail) 1 NA Homo sapiens

Genome Data NAX004487 CDKN2A (more detail) 1 NA Homo sapiens

Genome Data NAX002689 ZMPSTE24 (more detail) 1 NA Homo sapiens

Genome Data NAX017055 CDON (more detail) 1 NA Homo sapiens

Genome Data MEX001444 Genes associated with Kinase Inhibitor GW644007X Genes associated with Kinase Inhibitor GW644007X, curated by the Drug Signature Database (DSigDB). (more detail) 1 25990557 Homo sapiens

DSigDB NAX015094 GK (more detail) 1 NA Homo sapiens

Genome Data NAX018143 HSD3B2 (more detail) 1 NA Homo sapiens

Genome Data MEX003513 Genes associated with Perturbagen Signature lymecycline Genes associated with Perturbagen Signature lymecycline, curated by the Drug Signature Database (DSi (more detail) 1 25990557 Homo sapiens

DSigDB MEX001624 Genes associated with Kinase Inhibitor CHEMBL519697 Genes associated with Kinase Inhibitor CHEMBL519697, curated by the Drug Signature Database (DSigDB) (more detail) 1 25990557 Homo sapiens

DSigDB MEX001493 Genes associated with Kinase Inhibitor Chk2 Inhibitor II Genes associated with Kinase Inhibitor Chk2 Inhibitor II, curated by the Drug Signature Database (DS (more detail) 1 25990557 Homo sapiens

DSigDB MEX001513 Genes associated with Kinase Inhibitor Kinome 731 Genes associated with Kinase Inhibitor Kinome_731, curated by the Drug Signature Database (DSigDB). (more detail) 1 25990557 Homo sapiens

DSigDB MOX000242 Genes associated with Computational Drug Signature Cortivazol Genes associated with Computational Drug Signature Cortivazol, curated by the Drug Signature Databas (more detail) 1 25990557 Homo sapiens

DSigDB MOX005999 Genes associated with Computational Drug Signature 4 (6 methoxy 3,4 dihydronaphthalen 2 yl)pyridine Genes associated with Computational Drug Signature 4-(6-methoxy-3,4-dihydronaphthalen-2-yl)pyridine, (more detail) 1 25990557 Homo sapiens

DSigDB MOX005364 Genes associated with Computational Drug Signature 1 (3 Bromobenzyl) 1H imidazole Genes associated with Computational Drug Signature 1-(3-Bromobenzyl)-1H-imidazole, curated by the Dr (more detail) 1 25990557 Homo sapiens

DSigDB MOX005403 Genes associated with Computational Drug Signature 1 Chloro 4 (2,2 dichloro 1 (4 chlorophenyl)ethenyl) 3 (methylsulfonyl)benzene Genes associated with Computational Drug Signature 1-Chloro-4-(2,2-dichloro-1-(4-chlorophenyl)etheny (more detail) 1 25990557 Homo sapiens

DSigDB MOX005836 Genes associated with Computational Drug Signature 3 (3 methyl 3,4 dihydronaphthalen 2 yl)pyridine Genes associated with Computational Drug Signature 3-(3-methyl-3,4-dihydronaphthalen-2-yl)pyridine, (more detail) 1 25990557 Homo sapiens

DSigDB MOX006676 Genes associated with Computational Drug Signature AGN PC 00AYHI Genes associated with Computational Drug Signature AGN-PC-00AYHI, curated by the Drug Signature Data (more detail) 1 25990557 Homo sapiens

DSigDB MOX005850 Genes associated with Computational Drug Signature 3 (6 bromonaphthalen 2 yl)pyridine Genes associated with Computational Drug Signature 3-(6-bromonaphthalen-2-yl)pyridine, curated by th (more detail) 1 25990557 Homo sapiens

DSigDB MOX006458 Genes associated with Computational Drug Signature A 348441 Genes associated with Computational Drug Signature A-348441, curated by the Drug Signature Database (more detail) 1 25990557 Homo sapiens

DSigDB MOX005223 Genes associated with Computational Drug Signature (3 Pyridylmethylene)indane 24a Genes associated with Computational Drug Signature (3-Pyridylmethylene)indane 24a, curated by the Dr (more detail) 1 25990557 Homo sapiens

DSigDB MOX005226 Genes associated with Computational Drug Signature (3 Pyridylmethylene)indane 5a Genes associated with Computational Drug Signature (3-Pyridylmethylene)indane 5a, curated by the Dru (more detail) 1 25990557 Homo sapiens

DSigDB MOX003224 Genes associated with Computational Drug Signature 4 CHLORO 2 METHYLPHENOL Genes associated with Computational Drug Signature 4-CHLORO-2-METHYLPHENOL, curated by the Drug Sign (more detail) 1 25990557 Homo sapiens

DSigDB MOX010742 Genes associated with Computational Drug Signature CHEMBL459071 Genes associated with Computational Drug Signature CHEMBL459071, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX010757 Genes associated with Computational Drug Signature CHEMBL461457 Genes associated with Computational Drug Signature CHEMBL461457, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX011088 Genes associated with Computational Drug Signature CHEMBL509971 Genes associated with Computational Drug Signature CHEMBL509971, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX007958 Genes associated with Computational Drug Signature CHEMBL1172559 Genes associated with Computational Drug Signature CHEMBL1172559, curated by the Drug Signature Data (more detail) 1 25990557 Homo sapiens

DSigDB MOX007962 Genes associated with Computational Drug Signature CHEMBL1172883 Genes associated with Computational Drug Signature CHEMBL1172883, curated by the Drug Signature Data (more detail) 1 25990557 Homo sapiens

DSigDB MOX008024 Genes associated with Computational Drug Signature CHEMBL122341 Genes associated with Computational Drug Signature CHEMBL122341, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX007538 Genes associated with Computational Drug Signature CCNCSAKWCRDHSRCC Genes associated with Computational Drug Signature CCNCSAKWCRDHSRCC, curated by the Drug Signature D (more detail) 1 25990557 Homo sapiens

DSigDB MOX009918 Genes associated with Computational Drug Signature CHEMBL379290 Genes associated with Computational Drug Signature CHEMBL379290, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX009921 Genes associated with Computational Drug Signature CHEMBL379436 Genes associated with Computational Drug Signature CHEMBL379436, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX013701 Genes associated with Computational Drug Signature Metyrapol Genes associated with Computational Drug Signature Metyrapol, curated by the Drug Signature Database (more detail) 1 25990557 Homo sapiens

DSigDB MOX009514 Genes associated with Computational Drug Signature CHEMBL29863 Genes associated with Computational Drug Signature CHEMBL29863, curated by the Drug Signature Databa (more detail) 1 25990557 Homo sapiens

DSigDB MOX010993 Genes associated with Computational Drug Signature CHEMBL500664 Genes associated with Computational Drug Signature CHEMBL500664, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX011010 Genes associated with Computational Drug Signature CHEMBL502542 Genes associated with Computational Drug Signature CHEMBL502542, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX011320 Genes associated with Computational Drug Signature CHEMBL565098 Genes associated with Computational Drug Signature CHEMBL565098, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB TAX028019 GO:0060594 biological process mammary gland specification The regionalization process in which the mammary line is specified. The mammary line is a ridge of e (more detail) 1 NA Homo sapiens

GOA TAX029891 GO:0072198 biological process mesenchymal cell proliferation involved in ureter development The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell popula (more detail) 1 NA Homo sapiens

GOA TAX029374 GO:0071301 biological process cellular response to vitamin B1 Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 1 NA Homo sapiens

GOA TAX017477 GO:0009061 biological process anaerobic respiration The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and f (more detail) 1 NA Homo sapiens

GOA TAX021963 GO:0033079 biological process immature T cell proliferation The expansion of an immature T cell population by cell division. (more detail) 1 NA Homo sapiens

GOA GEX167762 Glaucoma Common variants on chromosome 9p21 are associated with normal tension glaucoma. (more detail) 1 22792221 Homo sapiens

GWAS Catalog TAX014251 GO:0002458 biological process peripheral T cell tolerance induction Tolerance induction of T cells in the periphery, in this case, any location in the body other than t (more detail) 1 NA Homo sapiens

GOA TAX034422 GO:2000005 biological process negative regulation of metanephric S shaped body morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped b (more detail) 1 NA Homo sapiens

GOA TAX033465 GO:1904465 biological process negative regulation of matrix metallopeptidase secretion Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase (more detail) 1 NA Homo sapiens

GOA TAX028176 GO:0060875 biological process lateral semicircular canal development The progession of the lateral semicircular canal from its initial formation to the mature structure. (more detail) 1 NA Homo sapiens

GOA MOX017324 Genes associated with Computational Drug Signature MI 63 Genes associated with Computational Drug Signature MI-63, curated by the Drug Signature Database (DS (more detail) 1 25990557 Homo sapiens

DSigDB MOX011516 Genes associated with Computational Drug Signature CHEMBL591697 Genes associated with Computational Drug Signature CHEMBL591697, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX011582 Genes associated with Computational Drug Signature CHEMBL598789 Genes associated with Computational Drug Signature CHEMBL598789, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX011624 Genes associated with Computational Drug Signature CHEMBL607567 Genes associated with Computational Drug Signature CHEMBL607567, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX011632 Genes associated with Computational Drug Signature CHEMBL608437 Genes associated with Computational Drug Signature CHEMBL608437, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX011639 Genes associated with Computational Drug Signature CHEMBL610501 Genes associated with Computational Drug Signature CHEMBL610501, curated by the Drug Signature Datab (more detail) 1 25990557 Homo sapiens

DSigDB MOX015324 Genes associated with Computational Drug Signature SureCN4224793 Genes associated with Computational Drug Signature SureCN4224793, curated by the Drug Signature Data (more detail) 1 25990557 Homo sapiens

DSigDB MOX015391 Genes associated with Computational Drug Signature T6387866 Genes associated with Computational Drug Signature T6387866, curated by the Drug Signature Database (more detail) 1 25990557 Homo sapiens

DSigDB MOX015075 Genes associated with Computational Drug Signature Serdemetan Genes associated with Computational Drug Signature Serdemetan, curated by the Drug Signature Databas (more detail) 1 25990557 Homo sapiens

DSigDB IEI001975 Protein protein interactors of human gene CCDC82 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCDC82 (SwissProt ID (more detail) 1 17535438 Homo sapiens

I2D IEI008648 Protein protein interactors of human gene ND4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ND4 (SwissProt ID=A0 (more detail) 1 17535438 Homo sapiens

I2D IEI012200 Protein protein interactors of human gene SI from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SI (SwissProt ID=P14 (more detail) 1 17535438 Homo sapiens

I2D IEI008030 Protein protein interactors of human gene MLIP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MLIP (SwissProt ID=Q (more detail) 1 17535438 Homo sapiens