PAGER3: A Pathways, Annotated-lists and Gene signatures Electronic Repository Version 3

Query: biological_process regulation of metabolic process

Result Filters

Size of PAGs

Min

Max

Species

Data Source

PAGs related to the disease: 9313 PAGs

PAG ID	PAG Type	PAG Name	Size	Pubmed Reference	Organism	Data source	cohension

The M-type PAG-PAG relationships

Network Visualization

PAG_A	PAG_A_SIZE	PAG_B	PAG_B_SIZE	Overlap	Similarity score	LOGCDF

The R-type PAG-PAG relationships

GOA TAX028419 GO:0061383 biological process trabecula morphogenesis The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue el (more detail) 24 NA Homo sapiens

GOA IEI012134 Protein protein interactors of human gene SH2B2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH2B2 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D TAX026549 GO:0050718 biological process positive regulation of interleukin 1 beta secretion Any process that activates or increases the frequency, rate or extent of the regulated release of in (more detail) 24 NA Homo sapiens

GOA TAX028081 GO:0060706 biological process cell differentiation involved in embryonic placenta development The process in which a relatively unspecialized cell acquires specialized features of the embryonic (more detail) 24 NA Homo sapiens

GOA IEI014709 Protein protein interactors of human gene UPF3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UPF3A (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI003289 Protein protein interactors of human gene DACT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DACT1 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D TAX031822 GO:1900117 biological process regulation of execution phase of apoptosis Any process that modulates the frequency, rate or extent of execution phase of apoptosis. (more detail) 24 NA Homo sapiens

GOA TAX019032 GO:0016447 biological process somatic recombination of immunoglobulin gene segments The process in which immunoglobulin genes are formed through recombination of the germline genetic e (more detail) 24 NA Homo sapiens

GOA MOX000893 Genes associated with Computational Drug Signature Mitonafide Genes associated with Computational Drug Signature Mitonafide, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens

DSigDB WIG000072 Signaling events mediated by HDAC Class III (more detail) 24 NA Homo sapiens

MSigDB MOX002393 Genes associated with Computational Drug Signature Prolinedithiocarbamate Genes associated with Computational Drug Signature Prolinedithiocarbamate, curated by the Drug Signa (more detail) 24 25990557 Homo sapiens

DSigDB TAX018421 GO:0014896 biological process muscle hypertrophy The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ (more detail) 24 NA Homo sapiens

GOA MOX016778 Genes associated with Computational Drug Signature Quinomycin A Genes associated with Computational Drug Signature Quinomycin A, curated by the Drug Signature Datab (more detail) 24 25990557 Homo sapiens

DSigDB FEX002389 MultipleMyeloma Gutierrez10 29genes Table 4 Potential microRNA (miRNA)?mRNA interactions deregulated in the multiple myeloma (MM) with m (more detail) 24 20054351 Homo sapiens

GeneSigDB WIG000851 Genes involved in G0 and Early G1 (more detail) 24 NA Homo sapiens

MSigDB MOX014363 Genes associated with Computational Drug Signature parthenolide Genes associated with Computational Drug Signature parthenolide, curated by the Drug Signature Datab (more detail) 24 25990557 Homo sapiens

DSigDB WAG001059 a6b1 and a6b4 Integrin signaling (more detail) 24 NA Homo sapiens

NCI-Nature Curated WIG000505 Dorso ventral axis formation (more detail) 24 NA Homo sapiens

MSigDB MEX001039 Genes associated with Approved Drug clomiphene citrate Genes associated with Approved Drug clomiphene citrate, curated by the Drug Signature Database (DSig (more detail) 24 25990557 Homo sapiens

DSigDB WIG001593 nNOS Signaling at Neuronal Synapses nNOS Signaling at Neuronal Synapses (more detail) 24 NA Homo sapiens

Protein Lounge MEX000381 Genes associated with Approved Drug liothyronine Genes associated with Approved Drug liothyronine, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB FEX001362 Leukemia Bal05 24genes Table 5 Deregulation of TNFR-mediated apoptotic pathways in acutely HTLV-1 transformed cells (more detail) 24 15896717 Homo sapiens

GeneSigDB MOX004982 Genes associated with Computational Drug Signature doxazosin Genes associated with Computational Drug Signature doxazosin, curated by the Drug Signature Database (more detail) 24 25990557 Homo sapiens

DSigDB IEI010030 Protein protein interactors of human gene PLAU from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLAU (SwissProt ID=P (more detail) 32 17535438 Homo sapiens

I2D IEI007649 Protein protein interactors of human gene MAP2K5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP2K5 (SwissProt ID (more detail) 32 17535438 Homo sapiens

I2D IEI007056 Protein protein interactors of human gene KRT85 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KRT85 (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D IEI003781 Protein protein interactors of human gene DRAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DRAP1 (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D TAX017962 GO:0010543 biological process regulation of platelet activation Any process that modulates the rate or frequency of platelet activation. Platelet activation is a se (more detail) 32 NA Homo sapiens

GOA TAX019923 GO:0021510 biological process spinal cord development The process whose specific outcome is the progression of the spinal cord over time, from its formati (more detail) 32 NA Homo sapiens

GOA MOX006564 Genes associated with Computational Drug Signature AC1NUPCX Genes associated with Computational Drug Signature AC1NUPCX, curated by the Drug Signature Database (more detail) 32 25990557 Homo sapiens

DSigDB MOX003843 Genes associated with Computational Drug Signature chloroquine Genes associated with Computational Drug Signature chloroquine, curated by the Drug Signature Databa (more detail) 32 25990557 Homo sapiens

DSigDB TAX025219 GO:0045671 biological process negative regulation of osteoclast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentia (more detail) 26 NA Homo sapiens

GOA TAX033892 GO:1905354 cellular component exoribonuclease complex A protein complex which is capable of exoribonuclease activity. (more detail) 26 NA Homo sapiens

GOA IEI014851 Protein protein interactors of human gene VAV3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VAV3 (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens

I2D IEI003056 Protein protein interactors of human gene CSN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSN2 (SwissProt ID=P (more detail) 26 17535438 Homo sapiens

I2D IEI015874 Protein protein interactors of human gene ZZZ3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZZZ3 (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens

I2D IEI002551 Protein protein interactors of human gene CIB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CIB1 (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens

I2D IEI005917 Protein protein interactors of human gene HMMR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMMR (SwissProt ID=O (more detail) 26 17535438 Homo sapiens

I2D IEI010995 Protein protein interactors of human gene RAPGEF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAPGEF1 (SwissProt I (more detail) 26 17535438 Homo sapiens

I2D IEI009548 Protein protein interactors of human gene PBXIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PBXIP1 (SwissProt ID (more detail) 26 17535438 Homo sapiens

I2D TAX023324 GO:0036296 biological process response to increased oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 26 NA Homo sapiens

GOA IEI003435 Protein protein interactors of human gene DDX54 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX54 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D TAX023038 GO:0035710 biological process CD4 positive, alpha beta T cell activation The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure t (more detail) 26 NA Homo sapiens

GOA IEI011872 Protein protein interactors of human gene SCN5A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCN5A (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D WIG000192 VEGFR1 specific signals (more detail) 26 NA Homo sapiens

MSigDB WAG001063 Trk receptor signaling mediated by PI3K and PLC gamma (more detail) 26 NA Homo sapiens

NCI-Nature Curated WIG001569 iNOS Signaling iNOS Signaling (more detail) 26 NA Homo sapiens

Protein Lounge MOX003461 Genes associated with Computational Drug Signature MLS000766263 Genes associated with Computational Drug Signature MLS000766263, curated by the Drug Signature Datab (more detail) 26 25990557 Homo sapiens

DSigDB MOX000673 Genes associated with Computational Drug Signature hmba Genes associated with Computational Drug Signature hmba, curated by the Drug Signature Database (DSi (more detail) 26 25990557 Homo sapiens

DSigDB MOX000005 Genes associated with Computational Drug Signature Aristolochic acid Genes associated with Computational Drug Signature Aristolochic acid, curated by the Drug Signature (more detail) 26 25990557 Homo sapiens

DSigDB TAX013295 GO:0000178 cellular component exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuc (more detail) 26 NA Homo sapiens

GOA MOX017425 Genes associated with Computational Drug Signature nutlin 3B Genes associated with Computational Drug Signature nutlin-3B, curated by the Drug Signature Database (more detail) 26 25990557 Homo sapiens

DSigDB WIG000264 Regulation of BAD phosphorylation The function of the pro-apoptotic molecule BAD is regulated by phosphorylation of three sites (ser 1 (more detail) 26 NA Homo sapiens

MSigDB TAX014356 GO:0002675 biological process positive regulation of acute inflammatory response Any process that activates or increases the frequency, rate, or extent of an acute inflammatory resp (more detail) 26 NA Homo sapiens

GOA MEX002158 Genes associated with Kinase Inhibitor Enzastaurin Genes associated with Kinase Inhibitor Enzastaurin, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens

DSigDB WAG000010 bcr signaling pathway Significant progress has been made towards delineation of the intrinsic molecular processes that reg (more detail) 26 NA Homo sapiens

BioCarta TAX014419 GO:0002756 biological process MyD88 independent toll like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor not re (more detail) 26 NA Homo sapiens

GOA TAX000166 Genes annotated by the GO term GO:0045137. The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion. (more detail) 26 NA Homo sapiens

MSigDB TAX023462 GO:0038034 biological process signal transduction in absence of ligand A series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand fro (more detail) 30 NA Homo sapiens

GOA TAX030736 GO:0097192 biological process extrinsic apoptotic signaling pathway in absence of ligand A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apo (more detail) 30 NA Homo sapiens

GOA IEI007336 Protein protein interactors of human gene LMO7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LMO7 (SwissProt ID=Q (more detail) 30 17535438 Homo sapiens

I2D IEI006814 Protein protein interactors of human gene KIF11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIF11 (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D IEI005085 Protein protein interactors of human gene GATAD2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GATAD2A (SwissProt I (more detail) 30 17535438 Homo sapiens

I2D MEX003497 Genes associated with Perturbagen Signature loperamide Genes associated with Perturbagen Signature loperamide, curated by the Drug Signature Database (DSig (more detail) 30 25990557 Homo sapiens

DSigDB MOX003978 Genes associated with Computational Drug Signature Digitoxigenin Genes associated with Computational Drug Signature Digitoxigenin, curated by the Drug Signature Data (more detail) 30 25990557 Homo sapiens

DSigDB WIG000020 Aurora A signaling (more detail) 30 NA Homo sapiens

MSigDB WIG000051 Ephrin B reverse signaling (more detail) 30 NA Homo sapiens

MSigDB MEX003714 Genes associated with Perturbagen Signature nifuroxazide Genes associated with Perturbagen Signature nifuroxazide, curated by the Drug Signature Database (DS (more detail) 30 25990557 Homo sapiens

DSigDB MEX000535 Genes associated with Approved Drug daunorubicin Genes associated with Approved Drug daunorubicin, curated by the Drug Signature Database (DSigDB). (more detail) 30 25990557 Homo sapiens

DSigDB WIG001956 Ovarian Infertility Genes Ovarian Infertility Genes (more detail) 30 NA Homo sapiens

WikiPathway IEI015103 Protein protein interactors of human gene XBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XBP1 (SwissProt ID=P (more detail) 28 17535438 Homo sapiens

I2D IEI007235 Protein protein interactors of human gene LGALS8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LGALS8 (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D IEI012956 Protein protein interactors of human gene SRCAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRCAP (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D TAX034481 GO:2000108 biological process positive regulation of leukocyte apoptotic process Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process (more detail) 28 NA Homo sapiens

GOA TAX022792 GO:0035265 biological process organ growth The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structure (more detail) 28 NA Homo sapiens

GOA IEI003898 Protein protein interactors of human gene EAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EAF1 (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI014137 Protein protein interactors of human gene TPP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TPP1 (SwissProt ID=O (more detail) 28 17535438 Homo sapiens

I2D IEI011182 Protein protein interactors of human gene RERE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RERE (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI005980 Protein protein interactors of human gene HOXB9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXB9 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D TAX026979 GO:0051385 biological process response to mineralocorticoid Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 28 NA Homo sapiens

GOA IEI015556 Protein protein interactors of human gene ZNF446 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF446 (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D IEI007608 Protein protein interactors of human gene MAGOHB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAGOHB (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D WAG000634 mcalpain and friends in cell motility The mammalian calpain gene family curently contains 13 distinct large subunit products most of which (more detail) 28 NA Homo sapiens

BioCarta TAX000692 Genes annotated by the GO term GO:0050863. Any process that modulates the frequency, rate or extent of T cell activation. (more detail) 28 NA Homo sapiens

MSigDB MOX004549 Genes associated with Computational Drug Signature podophyllotoxin Genes associated with Computational Drug Signature podophyllotoxin, curated by the Drug Signature Da (more detail) 28 25990557 Homo sapiens

DSigDB MOX000219 Genes associated with Computational Drug Signature Honokiol Genes associated with Computational Drug Signature Honokiol, curated by the Drug Signature Database (more detail) 28 25990557 Homo sapiens

DSigDB MOX004526 Genes associated with Computational Drug Signature phosphatidylcholines Genes associated with Computational Drug Signature phosphatidylcholines, curated by the Drug Signatu (more detail) 28 25990557 Homo sapiens

DSigDB MOX005343 Genes associated with Computational Drug Signature 1,9 Pyrazoloanthrone Genes associated with Computational Drug Signature 1,9-Pyrazoloanthrone, curated by the Drug Signatu (more detail) 28 25990557 Homo sapiens

DSigDB MAX000508 Genes down regulated in pilocytic astrocytoma compared to glioblastoma samples. Glioblastoma (GBM) is a highly malignant glioma, which has the propensity to infiltrate throughout t (more detail) 28 NA Homo sapiens

MSigDB MOX016828 Genes associated with Computational Drug Signature ETHACRYNIC ACID Genes associated with Computational Drug Signature ETHACRYNIC ACID, curated by the Drug Signature Da (more detail) 28 25990557 Homo sapiens

DSigDB IEI015323 Protein protein interactors of human gene ZFPM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZFPM2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI013773 Protein protein interactors of human gene TLX3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLX3 (SwissProt ID=O (more detail) 17 17535438 Homo sapiens

I2D IEI001209 Protein protein interactors of human gene BACH2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BACH2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX020391 GO:0030224 biological process monocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized feat (more detail) 17 NA Homo sapiens

GOA TAX024026 GO:0042800 molecular function histone methyltransferase activity (H3 K4 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L (more detail) 17 NA Homo sapiens

GOA IEI005816 Protein protein interactors of human gene HEXIM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HEXIM2 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI011123 Protein protein interactors of human gene RCAN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RCAN1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX034605 GO:2000319 biological process regulation of T helper 17 cell differentiation Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation. (more detail) 17 NA Homo sapiens

GOA TAX032809 GO:1903131 biological process mononuclear cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mononucl (more detail) 17 NA Homo sapiens

GOA TAX027582 GO:0055106 molecular function ubiquitin protein transferase regulator activity Modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent att (more detail) 17 NA Homo sapiens

GOA IEI003569 Protein protein interactors of human gene DIS3L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIS3L (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX027745 GO:0060216 biological process definitive hemopoiesis A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem ce (more detail) 17 NA Homo sapiens

GOA IEI008855 Protein protein interactors of human gene NKIRAS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NKIRAS1 (SwissProt I (more detail) 17 17535438 Homo sapiens

I2D IEI000572 Protein protein interactors of human gene ANGPTL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANGPTL4 (SwissProt I (more detail) 17 17535438 Homo sapiens

I2D IEI004235 Protein protein interactors of human gene EPSTI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPSTI1 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D TAX034496 GO:2000136 biological process regulation of cell proliferation involved in heart morphogenesis Any process that modulates the frequency, rate or extent of cell proliferation involved in heart mor (more detail) 17 NA Homo sapiens

GOA IEI002735 Protein protein interactors of human gene CNOT6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNOT6 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI008264 Protein protein interactors of human gene MS4A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MS4A2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D WIG001966 Mitochondrial Gene Expression Mitochondrial Gene Expression (more detail) 17 NA Homo sapiens

WikiPathway MEX000868 Genes associated with Approved Drug alitretinoin Genes associated with Approved Drug alitretinoin, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB WIG000711 Genes involved in ARMS mediated activation (more detail) 17 NA Homo sapiens

MSigDB TAX001415 Genes annotated by the GO term GO:0046966. Interacting selectively with a thyroid hormone receptor. (more detail) 17 NA Homo sapiens

MSigDB WIG001596 NTHi Induced Signaling NTHi-Induced Signaling (more detail) 17 NA Homo sapiens

Protein Lounge MAX002558 Genes encoding substrates of IkappaB kinase (IKK) complex. Transcription factors of the NF-kappaB family regulate hundreds of genes in the context of multiple (more detail) 17 NA Homo sapiens

MSigDB MAX001398 Genes down regulated in H1975 cells (non small cell lung cancer, NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL 387785 [PubChem=2776] for 6h. Activating mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase domain determine (more detail) 17 NA Homo sapiens

MSigDB WIG000244 The 4 1BB dependent immune response The activation of T cells requires a co-stimulatory signal with T cell receptor activation, provided (more detail) 17 NA Homo sapiens

MSigDB FEX001157 Immune Kong10 17genes ImmPort Interferons ImmPort genelist of cytokines: Interferons (more detail) 17 20460173 Homo sapiens

GeneSigDB FEX001890 Lung Kobayashi06 18genes Table 1b. Genes up-regulated by CL-387 785 at 6 hours (more detail) 17 17145885 Homo sapiens

GeneSigDB WIG000407 Regulation of transcriptional activity by PML The PML nuclear bodies are ring-shaped nuclear substructures associated with the regulation of trans (more detail) 17 NA Homo sapiens

MSigDB MEX002318 Genes associated with Kinase Inhibitor GW801372X Genes associated with Kinase Inhibitor GW801372X, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB WIG000170 Regulation of cytoplasmic and nuclear SMAD2/3 signaling (more detail) 17 NA Homo sapiens

MSigDB WIG000450 TNFR2 Signaling Pathway TNFR2 is the receptor for the 171 amino acid 19 kD TNF(beta) (a.k.a. lymphotoxin). TNF(beta) is prod (more detail) 17 NA Homo sapiens

MSigDB MOX004184 Genes associated with Computational Drug Signature HEXACHLOROBENZENE Genes associated with Computational Drug Signature HEXACHLOROBENZENE, curated by the Drug Signature (more detail) 17 25990557 Homo sapiens

DSigDB WIG000316 Role of Erk5 in Neuronal Survival Axons extend significant distances to innervate target tissues. At the site of innervation, target t (more detail) 17 NA Homo sapiens

MSigDB MOX014380 Genes associated with Computational Drug Signature PD 173074 Genes associated with Computational Drug Signature PD 173074, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens

DSigDB TAX000419 Genes annotated by the GO term GO:0051402. The process of apoptosis in neurons, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. (more detail) 17 NA Homo sapiens

MSigDB WIG000259 Tumor Suppressor Arf Inhibits Ribosomal Biogenesis Cyclin-dependent kinase inhibitor-2A (CDKN2A) goes by the colloquial designation p16, which is somet (more detail) 17 NA Homo sapiens

MSigDB MOX003478 Genes associated with Computational Drug Signature NVP TAE684 Genes associated with Computational Drug Signature NVP-TAE684, curated by the Drug Signature Databas (more detail) 17 25990557 Homo sapiens

DSigDB TAX015601 GO:0005123 molecular function death receptor binding Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR (more detail) 17 NA Homo sapiens

GOA TAX033966 GO:1905523 biological process positive regulation of macrophage migration Any process that activates or increases the frequency, rate or extent of macrophage migration. (more detail) 14 NA Homo sapiens

GOA TAX034813 GO:2000615 biological process regulation of histone H3 K9 acetylation Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation. (more detail) 14 NA Homo sapiens

GOA TAX027774 GO:0060263 biological process regulation of respiratory burst Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, d (more detail) 14 NA Homo sapiens

GOA TAX022561 GO:0034616 biological process response to laminar fluid shear stress Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 14 NA Homo sapiens

GOA TAX025326 GO:0045898 biological process regulation of RNA polymerase II transcriptional preinitiation complex assembly Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preini (more detail) 14 NA Homo sapiens

GOA TAX025232 GO:0045717 biological process negative regulation of fatty acid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 14 NA Homo sapiens

GOA TAX028214 GO:0060967 biological process negative regulation of gene silencing by RNA Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing b (more detail) 14 NA Homo sapiens

GOA TAX022068 GO:0033276 cellular component transcription factor TFTC complex A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, bu (more detail) 14 NA Homo sapiens

GOA TAX021777 GO:0032785 biological process negative regulation of DNA templated transcription, elongation Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongati (more detail) 14 NA Homo sapiens

GOA TAX022896 GO:0035497 molecular function cAMP response element binding Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palin (more detail) 14 NA Homo sapiens

GOA TAX030807 GO:0097341 biological process zymogen inhibition Any process that prevents the proteolytic processing of an inactive enzyme to an active form. (more detail) 14 NA Homo sapiens

GOA TAX024404 GO:0043508 biological process negative regulation of JUN kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity. (more detail) 14 NA Homo sapiens

GOA TAX016818 GO:0007175 biological process negative regulation of epidermal growth factor activated receptor activity Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor (more detail) 14 NA Homo sapiens

GOA TAX028525 GO:0061647 biological process histone H3 K9 modification The modification of histone H3 at a lysine in position 9 of the histone. (more detail) 14 NA Homo sapiens

GOA TAX022133 GO:0033549 molecular function MAP kinase phosphatase activity Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate. (more detail) 14 NA Homo sapiens

GOA TAX022465 GO:0034393 biological process positive regulation of smooth muscle cell apoptotic process Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptot (more detail) 14 NA Homo sapiens

GOA TAX030395 GO:0090192 biological process regulation of glomerulus development Any process that modulates the rate, frequency or extent of glomerulus development, the progression (more detail) 14 NA Homo sapiens

GOA TAX029906 GO:0072216 biological process positive regulation of metanephros development Any process that increases the rate, frequency or extent of metanephros development. Metanephros dev (more detail) 14 NA Homo sapiens

GOA TAX021563 GO:0032454 molecular function histone demethylase activity (H3 K9 specific) Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = s (more detail) 14 NA Homo sapiens

GOA TAX027638 GO:0060049 biological process regulation of protein glycosylation Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosyla (more detail) 14 NA Homo sapiens

GOA TAX033771 GO:1905063 biological process regulation of vascular smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiat (more detail) 14 NA Homo sapiens

GOA IEI001752 Protein protein interactors of human gene CAMK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAMK4 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX021103 GO:0031657 biological process regulation of cyclin dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threon (more detail) 14 NA Homo sapiens

GOA TAX027703 GO:0060149 biological process negative regulation of posttranscriptional gene silencing Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a (more detail) 14 NA Homo sapiens

GOA TAX028793 GO:0070198 biological process protein localization to chromosome, telomeric region Any process in which a protein is transported to, or maintained at, the telomeric region of a chromo (more detail) 14 NA Homo sapiens

GOA IEI009052 Protein protein interactors of human gene NRF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NRF1 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D TAX030307 GO:0090069 biological process regulation of ribosome biogenesis Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis (more detail) 14 NA Homo sapiens

GOA TAX028098 GO:0060732 biological process positive regulation of inositol phosphate biosynthetic process Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inosito (more detail) 14 NA Homo sapiens

GOA TAX029542 GO:0071565 cellular component nBAF complex A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and protei (more detail) 14 NA Homo sapiens

GOA TAX030806 GO:0097340 biological process inhibition of cysteine type endopeptidase activity Any process that prevents the activation of an inactive cysteine-type endopeptidase. (more detail) 14 NA Homo sapiens

GOA IEI009783 Protein protein interactors of human gene PFKFB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PFKFB2 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI010275 Protein protein interactors of human gene POU1F1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POU1F1 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D WIG000305 Repression of Pain Sensation by the Transcriptional Regulator DREAM The molecular events that lead to the perception of pain are a key research field in medicine and dr (more detail) 14 NA Homo sapiens

MSigDB TAX001363 Genes annotated by the GO term GO:0003705. Functions to initiate or regulate RNA polymerase II transcription by binding an enhancer region of DNA. (more detail) 14 NA Homo sapiens

MSigDB MOX001428 Genes associated with Computational Drug Signature NSC267099 Genes associated with Computational Drug Signature NSC267099, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB WAG001326 MicroRNA biogenesis (more detail) 14 NA Homo sapiens

Reactome TAX000272 Genes annotated by the GO term GO:0000188. Any process that terminates the activity of the active enzyme MAP kinase. (more detail) 14 NA Homo sapiens

MSigDB TAX000579 Genes annotated by the GO term GO:0003002. The pattern specification process by which an axis or axes is subdivided in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. (more detail) 14 NA Homo sapiens

MSigDB MEX001945 Genes associated with Kinase Inhibitor Kinome 239 Genes associated with Kinase Inhibitor Kinome_239, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB PEX001100 Myb DNA binding: Myb like DNA binding domain This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family 1. (more detail) 14 NA Homo sapiens

Pfam PEX002614 CARD: Caspase recruitment domain Motif contained in proteins involved in apoptotic signaling. Predicted to possess a DEATH (Pfam:PF00 (more detail) 14 NA Homo sapiens

Pfam TAX013934 GO:0001921 biological process positive regulation of receptor recycling Any process that activates or increases the frequency, rate or extent of receptor recycling. (more detail) 14 NA Homo sapiens

GOA PEX002160 HLH: Helix loop helix DNA binding domain (more detail) 14 NA Homo sapiens

Pfam WAG001454 repression of pain sensation by the transcriptional regulator dream The molecular events that lead to the perception of pain are a key research field in medicine and dr (more detail) 14 NA Homo sapiens

BioCarta FEX003153 StemCell Novakova10 21genes Table 2. List of cytokines with transcripts upregulated by 10??m BrdU+DMA (more detail) 14 19802007 Homo sapiens

GeneSigDB MAX003281 An assortment of osteoblast transcriptional regulators. The use of genetically manipulated mouse models, gene and protein discovery and the cataloguing of g (more detail) 14 NA Homo sapiens

MSigDB WAG000252 RXR and RAR hetrodimerization with other nuclear receptor (more detail) 14 NA Homo sapiens

NCI-Nature Curated TAX013285 GO:0000164 cellular component protein phosphatase type 1 complex A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosp (more detail) 14 NA Homo sapiens

GOA TAX000173 Genes annotated by the GO term GO:0008630. A cascade of processes initiated by the detection of DNA damage and resulting in the induction of apoptosis (programmed cell death). (more detail) 14 NA Homo sapiens

MSigDB WIG001315 Genes involved in Viral Messenger RNA Synthesis (more detail) 14 NA Homo sapiens

MSigDB MEX002228 Genes associated with Kinase Inhibitor Kinome 3196 Genes associated with Kinase Inhibitor Kinome_3196, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB TAX015333 GO:0004707 molecular function MAP kinase activity Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphoryla (more detail) 14 NA Homo sapiens

GOA WIG000410 Presenilin action in Notch and Wnt signaling Presenilin-1 (PS1) is associated with gamma secretase activity that cleaves amyloid precursor protei (more detail) 14 NA Homo sapiens

MSigDB WIG000281 CD40L Signaling Pathway The CD40 receptor was first associated with expression in B cells and the role it plays through its (more detail) 14 NA Homo sapiens

MSigDB WIG000292 Classical Complement Pathway The complement system is part of the defense against invading cells and is composed of about twenty (more detail) 14 NA Homo sapiens

MSigDB MEX001318 Genes associated with Kinase Inhibitor Ibrutinib Genes associated with Kinase Inhibitor Ibrutinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX000003 Genes associated with Computational Drug Signature Alpinumisoflavone Genes associated with Computational Drug Signature Alpinumisoflavone, curated by the Drug Signature (more detail) 14 25990557 Homo sapiens

DSigDB TAX001044 Genes annotated by the GO term GO:0005669. A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters. (more detail) 14 NA Homo sapiens

MSigDB MEX002419 Genes associated with Kinase Inhibitor Ibrutinib Genes associated with Kinase Inhibitor Ibrutinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB WAG000829 stress induction of hsp regulation Mammalian cells can respond to a variety of stresses such as heat, cold, oxidative stress, metabolic (more detail) 14 NA Homo sapiens

BioCarta FEX002302 Lymphoma Staege08 26genes Figure 2a. Examples of Hodgkin (more detail) 14 18400362 Homo sapiens

GeneSigDB TAX000283 Genes annotated by the GO term GO:0032609. The appearance of interferon gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. (more detail) 14 NA Homo sapiens

MSigDB MEX002283 Genes associated with Kinase Inhibitor Kinome 708 Genes associated with Kinase Inhibitor Kinome_708, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB WAG000444 Atypical NF kappaB pathway (more detail) 14 NA Homo sapiens

NCI-Nature Curated MAX002048 Composition of the 2 MDa human STAGA complex containing KAT2A [GeneID=2648]. Transcription in eukaryotes is a tightly regulated, multistep process. Gene-specific transcriptional (more detail) 14 NA Homo sapiens

MSigDB WIG001000 Genes involved in mRNA Decay by 5' to 3' Exoribonuclease (more detail) 14 NA Homo sapiens

MSigDB TAX000410 Genes annotated by the GO term GO:0043433. Any process that stops, prevents or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. (more detail) 14 NA Homo sapiens

MSigDB IEI012119 Protein protein interactors of human gene SGK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SGK2 (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D TAX032678 GO:1902884 biological process positive regulation of response to oxidative stress Any process that activates or increases the frequency, rate or extent of response to oxidative stres (more detail) 19 NA Homo sapiens

GOA TAX035145 GO:2001275 biological process positive regulation of glucose import in response to insulin stimulus Any process that activates or increases the frequency, rate or extent of glucose import in response (more detail) 19 NA Homo sapiens

GOA IEI011023 Protein protein interactors of human gene RASGRF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RASGRF1 (SwissProt I (more detail) 19 17535438 Homo sapiens

I2D IEI014301 Protein protein interactors of human gene TRMT1L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRMT1L (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI000196 Protein protein interactors of human gene ACTR5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACTR5 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX034602 GO:2000316 biological process regulation of T helper 17 type immune response Any process that modulates the frequency, rate or extent of T-helper 17 type immune response. (more detail) 19 NA Homo sapiens

GOA IEI004148 Protein protein interactors of human gene EMSY from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EMSY (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D TAX018044 GO:0010667 biological process negative regulation of cardiac muscle cell apoptotic process Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programme (more detail) 19 NA Homo sapiens

GOA IEI011109 Protein protein interactors of human gene RBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBP1 (SwissProt ID=P (more detail) 19 17535438 Homo sapiens

I2D IEI003362 Protein protein interactors of human gene DCP1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCP1B (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX026070 GO:0048156 molecular function tau protein binding Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein (more detail) 19 NA Homo sapiens

GOA IEI012877 Protein protein interactors of human gene SPIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPIN1 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX034889 GO:2000727 biological process positive regulation of cardiac muscle cell differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differe (more detail) 19 NA Homo sapiens

GOA IEI001292 Protein protein interactors of human gene BCL7C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCL7C (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX023857 GO:0042474 biological process middle ear morphogenesis The process in which the anatomical structures of the middle ear are generated and organized. The mi (more detail) 19 NA Homo sapiens

GOA IEI005819 Protein protein interactors of human gene HEYL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HEYL (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D TAX027198 GO:0051797 biological process regulation of hair follicle development Any process that modulates the frequency, rate or extent of hair follicle development. (more detail) 19 NA Homo sapiens

GOA FEX001685 Liver Li03 25genes Table 1 Genes with differential expression between MHCC97-L and HCCLM3 (more detail) 19 12618900 Homo sapiens

GeneSigDB MEX002301 Genes associated with Kinase Inhibitor TCMDC 138201 Genes associated with Kinase Inhibitor TCMDC-138201, curated by the Drug Signature Database (DSigDB) (more detail) 19 25990557 Homo sapiens

DSigDB MEX001890 Genes associated with Kinase Inhibitor Kinome 1221 Genes associated with Kinase Inhibitor Kinome_1221, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB MOX001235 Genes associated with Computational Drug Signature FLAVANONE Genes associated with Computational Drug Signature FLAVANONE, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB MEX002268 Genes associated with Kinase Inhibitor indirubin deriv. 7a Genes associated with Kinase Inhibitor indirubin deriv. 7a, curated by the Drug Signature Database ( (more detail) 19 25990557 Homo sapiens

DSigDB MOX003949 Genes associated with Computational Drug Signature DIAMIDE Genes associated with Computational Drug Signature DIAMIDE, curated by the Drug Signature Database ( (more detail) 19 25990557 Homo sapiens

DSigDB MAX003307 Genes up regulated in HL 60 cells (promyeloid leukemia) by cantharidin [PubChem=6708701]. Cantharidin is a natural toxin that has antitumor properties and causes leukocytosis as well as incr (more detail) 19 NA Homo sapiens

MSigDB WIG001108 Genes involved in Prolonged ERK activation events (more detail) 19 NA Homo sapiens

MSigDB WAG000007 role of mal in rho mediated activation of srf Serum response factor (SRF) is a transcription factor, which binds to a serum response element (SRE) (more detail) 19 NA Homo sapiens

BioCarta WIG002035 Estrogen signaling pathway Estrogen signaling pathway (more detail) 19 NA Homo sapiens

WikiPathway MAX002753 Genes down regulated in MCF10A cells (breast cancer) by expression of LSM1 [GeneID=27257] off a letiviral vector. Amplification of the 8p11-12 region occurs in 15-20% of breast cancers, but the driving oncogene at (more detail) 19 NA Homo sapiens

MSigDB WIG000371 Role of MAL in Rho Mediated Activation of SRF Serum response factor (SRF) is a transcription factor, which binds to a serum response element (SRE) (more detail) 19 NA Homo sapiens

MSigDB WAG000640 role of erk5 in neuronal survival pathway Axons extend significant distances to innervate target tissues. At the site of innervation, target (more detail) 19 NA Homo sapiens

BioCarta WIG000048 EPHA2 forward signaling (more detail) 19 NA Homo sapiens

MSigDB TAX014199 GO:0002360 biological process T cell lineage commitment The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell. (more detail) 19 NA Homo sapiens

GOA WAG000813 Maturity onset diabetes of the young About 2-5% of type II diabetic patients suffer from a monogenic disease with autosomal domint inheri (more detail) 19 NA Homo sapiens

KEGG TAX000652 Genes annotated by the GO term GO:0045637. Any process that modulates the frequency, rate or extent of myeloid cell differentiation. (more detail) 19 NA Homo sapiens

MSigDB TAX027250 GO:0051900 biological process regulation of mitochondrial depolarization Any process that modulates the frequency, rate or extent of the change in the membrane potential of (more detail) 21 NA Homo sapiens

GOA TAX026044 GO:0048048 biological process embryonic eye morphogenesis The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are (more detail) 21 NA Homo sapiens

GOA IEI001376 Protein protein interactors of human gene BMP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BMP4 (SwissProt ID=P (more detail) 21 17535438 Homo sapiens

I2D TAX033673 GO:1904886 biological process beta catenin destruction complex disassembly The disaggregation of a beta-catenin destruction complex into its constituent components. (more detail) 21 NA Homo sapiens

GOA IEI009605 Protein protein interactors of human gene PCGF5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCGF5 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI012075 Protein protein interactors of human gene SETX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SETX (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI004020 Protein protein interactors of human gene EIF1AX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF1AX (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI015580 Protein protein interactors of human gene ZNF496 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF496 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D TAX023982 GO:0042730 biological process fibrinolysis A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the pro (more detail) 21 NA Homo sapiens

GOA WEX000027 ERBB2 Signaling The genes related to erbb2 signaling (signaling pathways) in tumor using next-generation sequencer ( (more detail) 21 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI005481 Protein protein interactors of human gene GRB14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRB14 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI003895 Protein protein interactors of human gene E2F7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene E2F7 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI011019 Protein protein interactors of human gene RASD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RASD2 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D TAX024395 GO:0043496 biological process regulation of protein homodimerization activity Any process that modulates the frequency, rate or extent of protein homodimerization, interacting se (more detail) 21 NA Homo sapiens

GOA MEX002324 Genes associated with Kinase Inhibitor CHEMBL1967116 Genes associated with Kinase Inhibitor CHEMBL1967116, curated by the Drug Signature Database (DSigDB (more detail) 21 25990557 Homo sapiens

DSigDB MOX003378 Genes associated with Computational Drug Signature TDZD 8 Genes associated with Computational Drug Signature TDZD-8, curated by the Drug Signature Database (D (more detail) 21 25990557 Homo sapiens

DSigDB MOX013771 Genes associated with Computational Drug Signature Molephantin Genes associated with Computational Drug Signature Molephantin, curated by the Drug Signature Databa (more detail) 21 25990557 Homo sapiens

DSigDB WIG000777 Genes involved in CTLA4 inhibitory signaling (more detail) 21 NA Homo sapiens

MSigDB MOX000537 Genes associated with Computational Drug Signature propachlor Genes associated with Computational Drug Signature propachlor, curated by the Drug Signature Databas (more detail) 21 25990557 Homo sapiens

DSigDB WIG001284 Genes involved in TRAF6 mediated NF kB activation (more detail) 21 NA Homo sapiens

MSigDB FEX000988 EmbryonicStemCell Soh07 27genes A Supplementary Table 7. List of growth factor (GF) and receptor (GFR) interaction pairs. Selection cr (more detail) 21 17823238 Homo sapiens

GeneSigDB WAG000045 Signaling events mediated by HDAC Class III (more detail) 21 NA Homo sapiens

NCI-Nature Curated FEX000729 Breast Lin09 24genes Additional File 1-5. A list of genes corresponding to certain breast cancer related pathways;Cell Cy (more detail) 21 19695104 Homo sapiens

GeneSigDB IEI002241 Protein protein interactors of human gene CDK12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK12 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D TAX032314 GO:1901976 biological process regulation of cell cycle checkpoint Any process that modulates the frequency, rate or extent of cell cycle checkpoint. (more detail) 31 NA Homo sapiens

GOA IEI006900 Protein protein interactors of human gene KLF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF6 (SwissProt ID=Q (more detail) 31 17535438 Homo sapiens

I2D IEI004074 Protein protein interactors of human gene ELAC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELAC2 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D TAX026530 GO:0050699 molecular function WW domain binding Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of (more detail) 31 NA Homo sapiens

GOA TAX020470 GO:0030332 molecular function cyclin binding Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies mark (more detail) 31 NA Homo sapiens

GOA IEI015559 Protein protein interactors of human gene ZNF451 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF451 (SwissProt ID (more detail) 31 17535438 Homo sapiens

I2D IEI013527 Protein protein interactors of human gene TDP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TDP2 (SwissProt ID=O (more detail) 31 17535438 Homo sapiens

I2D IEI002588 Protein protein interactors of human gene CLASP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLASP2 (SwissProt ID (more detail) 31 17535438 Homo sapiens

I2D IEI000089 Protein protein interactors of human gene ABLIM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABLIM1 (SwissProt ID (more detail) 31 17535438 Homo sapiens

I2D IEI000305 Protein protein interactors of human gene ADNP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADNP (SwissProt ID=Q (more detail) 31 17535438 Homo sapiens

I2D MEX000765 Genes associated with Approved Drug methotrexate Genes associated with Approved Drug methotrexate, curated by the Drug Signature Database (DSigDB). (more detail) 31 25990557 Homo sapiens

DSigDB MOX004479 Genes associated with Computational Drug Signature patulin Genes associated with Computational Drug Signature patulin, curated by the Drug Signature Database ( (more detail) 31 25990557 Homo sapiens

DSigDB MOX004260 Genes associated with Computational Drug Signature levodopa Genes associated with Computational Drug Signature levodopa, curated by the Drug Signature Database (more detail) 31 25990557 Homo sapiens

DSigDB FEX001405 Leukemia Erkeland06 107genes Supplementary Table 3c. Genes present in VIS identified in the BXH2 model and differentially express (more detail) 31 16423987 Homo sapiens

GeneSigDB MAX000801 Genes down regulated in immortalized cell lines. Bypassing cellular senescence and becoming immortal is a prerequisite step in the tumorigenic transf (more detail) 31 NA Homo sapiens

MSigDB WIG000172 Syndecan 2 mediated signaling events (more detail) 31 NA Homo sapiens

MSigDB WIG000390 Actions of Nitric Oxide in the Heart Nitric oxide (NO) has a number of important physiological actions in the cardiovascular system. In t (more detail) 31 NA Homo sapiens

MSigDB TAX031962 GO:1900740 biological process positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of protein insertion into mito (more detail) 23 NA Homo sapiens

GOA TAX031961 GO:1900739 biological process regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial mem (more detail) 23 NA Homo sapiens

GOA IEI008318 Protein protein interactors of human gene MTDH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTDH (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D TAX028771 GO:0070168 biological process negative regulation of biomineral tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue deve (more detail) 23 NA Homo sapiens

GOA TAX024032 GO:0042813 molecular function Wnt activated receptor activity Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a ch (more detail) 23 NA Homo sapiens

GOA IEI013340 Protein protein interactors of human gene TAF13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF13 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI006196 Protein protein interactors of human gene IFNG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFNG (SwissProt ID=P (more detail) 23 17535438 Homo sapiens

I2D IEI012659 Protein protein interactors of human gene SNAI2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNAI2 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI007407 Protein protein interactors of human gene LRP8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRP8 (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D TAX018236 GO:0010939 biological process regulation of necrotic cell death Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death (more detail) 23 NA Homo sapiens

GOA IEI001476 Protein protein interactors of human gene BTG2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BTG2 (SwissProt ID=P (more detail) 23 17535438 Homo sapiens

I2D TAX026634 GO:0050855 biological process regulation of B cell receptor signaling pathway Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cros (more detail) 23 NA Homo sapiens

GOA TAX026637 GO:0050858 biological process negative regulation of antigen receptor mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways ini (more detail) 23 NA Homo sapiens

GOA TAX026034 GO:0048027 molecular function mRNA 5' UTR binding Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule. (more detail) 23 NA Homo sapiens

GOA IEI000704 Protein protein interactors of human gene APAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APAF1 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI002242 Protein protein interactors of human gene CDK13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK13 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI004116 Protein protein interactors of human gene ELP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELP3 (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D FEX001178 InVitro Haouzi10 24genes Supplemental Table S2. List of growth factor (B) genes significantly modulated during the endometria (more detail) 23 20042535 Homo sapiens

GeneSigDB MOX002257 Genes associated with Computational Drug Signature U 73122 Genes associated with Computational Drug Signature U-73122, curated by the Drug Signature Database ( (more detail) 23 25990557 Homo sapiens

DSigDB WIG001441 Cellular Transformation by HTLV1 Cellular Transformation by HTLV1 (more detail) 23 NA Homo sapiens

Protein Lounge WIG000933 Genes involved in Insulin receptor recycling (more detail) 23 NA Homo sapiens

MSigDB WIG002001 Cytokines and Inflammatory Response Cytokines and Inflammatory Response (more detail) 23 NA Homo sapiens

WikiPathway WIG001634 Polyamine Regulation in Colon Cancer Polyamine Regulation in Colon Cancer (more detail) 23 NA Homo sapiens

Protein Lounge WAG000413 vegf hypoxia and angiogenesis Vascular endothelial growth factor (VEGF) plays a key role in physiological blood vessel formation a (more detail) 23 NA Homo sapiens

BioCarta MOX003692 Genes associated with Computational Drug Signature apomorphine Genes associated with Computational Drug Signature apomorphine, curated by the Drug Signature Databa (more detail) 23 25990557 Homo sapiens

DSigDB FEX003207 Stomach Takada05 29genes Table 3. Genes showing high-level amplifications and homozygous deletions among 31 gastric cancer ce (more detail) 23 15723654 Homo sapiens

GeneSigDB TAX031865 GO:1900181 biological process negative regulation of protein localization to nucleus Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to (more detail) 29 NA Homo sapiens

GOA IEI008279 Protein protein interactors of human gene MSL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MSL1 (SwissProt ID=Q (more detail) 29 17535438 Homo sapiens

I2D IEI014579 Protein protein interactors of human gene UBE2J1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2J1 (SwissProt ID (more detail) 29 17535438 Homo sapiens

I2D IEI010487 Protein protein interactors of human gene PRKCH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRKCH (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI001845 Protein protein interactors of human gene CAVIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAVIN1 (SwissProt ID (more detail) 29 17535438 Homo sapiens

I2D TAX033271 GO:1904037 biological process positive regulation of epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic p (more detail) 29 NA Homo sapiens

GOA IEI000835 Protein protein interactors of human gene ARHGEF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARHGEF1 (SwissProt I (more detail) 29 17535438 Homo sapiens

I2D IEI013450 Protein protein interactors of human gene TBPL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBPL1 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI013343 Protein protein interactors of human gene TAF1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF1B (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D WAG001058 Aurora A signaling (more detail) 29 NA Homo sapiens

NCI-Nature Curated MOX000702 Genes associated with Computational Drug Signature beta Lapachone Genes associated with Computational Drug Signature beta-Lapachone, curated by the Drug Signature Dat (more detail) 29 25990557 Homo sapiens

DSigDB PEX000431 DSPc: Dual specificity phosphatase, catalytic domain Ser/Thr and Tyr protein phosphatases. The enzymes tertiary fold is highly similar to that of tyrosin (more detail) 29 NA Homo sapiens

Pfam MOX013135 Genes associated with Computational Drug Signature INDIRUBIN 3' MONOXIME Genes associated with Computational Drug Signature INDIRUBIN-3'-MONOXIME, curated by the Drug Signat (more detail) 29 25990557 Homo sapiens

DSigDB WIG000457 VEGF, Hypoxia, and Angiogenesis Vascular endothelial growth factor (VEGF) plays a key role in physiological blood vessel formation a (more detail) 29 NA Homo sapiens

MSigDB FEX002234 Lymphoma Satoh05 30genes Non Tcells Table 3 Top 30 genes expressed differentially in non-T cells between MS and controls (more detail) 29 15755681 Homo sapiens

GeneSigDB FEX003411 Viral Feuerhake05 47genes Figure S4: Differential expression of NFkB target genes in Host Response (HR) DLBCL vs. non-HR DLBCL (more detail) 29 15870177 Homo sapiens

GeneSigDB TAX027828 GO:0060334 biological process regulation of interferon gamma mediated signaling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated (more detail) 25 NA Homo sapiens

GOA IEI009162 Protein protein interactors of human gene NUMBL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUMBL (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D TAX027280 GO:0051953 biological process negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement (more detail) 25 NA Homo sapiens

GOA TAX032937 GO:1903409 biological process reactive oxygen species biosynthetic process The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molec (more detail) 25 NA Homo sapiens

GOA TAX019446 GO:0018023 biological process peptidyl lysine trimethylation The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine. (more detail) 25 NA Homo sapiens

GOA IEI004818 Protein protein interactors of human gene FLT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FLT3 (SwissProt ID=P (more detail) 25 17535438 Homo sapiens

I2D IEI000058 Protein protein interactors of human gene ABCF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABCF2 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D TAX027824 GO:0060330 biological process regulation of response to interferon gamma Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response (more detail) 25 NA Homo sapiens

GOA TAX024915 GO:0045058 biological process T cell selection The process in which T cells that express T cell receptors that are restricted by self MHC protein c (more detail) 25 NA Homo sapiens

GOA IEI009744 Protein protein interactors of human gene PELI2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PELI2 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI003971 Protein protein interactors of human gene EFEMP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFEMP1 (SwissProt ID (more detail) 25 17535438 Homo sapiens

I2D IEI011610 Protein protein interactors of human gene RPS6KB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS6KB2 (SwissProt I (more detail) 25 17535438 Homo sapiens

I2D IEI012170 Protein protein interactors of human gene SHARPIN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SHARPIN (SwissProt I (more detail) 25 17535438 Homo sapiens

I2D TAX021107 GO:0031664 biological process regulation of lipopolysaccharide mediated signaling pathway Any process that modulates the frequency, rate or extent of signaling in response to detection of li (more detail) 25 NA Homo sapiens

GOA MAX001661 'Wilm's tumor signature': genes highly expressed in Wilm's tumor samples compared to normal fetal kidney and a heterologous tumor, Burkit lymphoma. Wilms' tumor (WT) has been considered a prototype for arrested cellular differentiation in cancer, b (more detail) 25 NA Homo sapiens

MSigDB FEX002268 Lypmhoma Leval07 28genes Table 3. Genes overexpressed in PTCL-u compared to AITL (more detail) 25 17284527 Homo sapiens

GeneSigDB MOX004398 Genes associated with Computational Drug Signature naloxone Genes associated with Computational Drug Signature naloxone, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB MEX002503 Genes associated with Perturbagen Signature 5253409 Genes associated with Perturbagen Signature 5253409, curated by the Drug Signature Database (DSigDB) (more detail) 25 25990557 Homo sapiens

DSigDB MEX001658 Genes associated with Kinase Inhibitor GW768505A Genes associated with Kinase Inhibitor GW768505A, curated by the Drug Signature Database (DSigDB). (more detail) 25 25990557 Homo sapiens

DSigDB MAX000630 Proteins shown to interact with LCA5 [GeneID=167691] in vivo. Leber congenital amaurosis (LCA) causes blindness or severe visual impairment at or within a few mon (more detail) 25 NA Homo sapiens

MSigDB MAX001700 Up regulated genes of putative pathways stimulated in tumor endothelial cells by papillary serous ovarian epithelial tumor cells. Therapeutic strategies based on antiangiogenic approaches are beginning to show great promise in cli (more detail) 25 NA Homo sapiens

MSigDB TAX016354 GO:0006471 biological process protein ADP ribosylation The transfer, from NAD, of ADP-ribose to protein amino acids. (more detail) 25 NA Homo sapiens

GOA MOX002959 Genes associated with Computational Drug Signature apicidin Genes associated with Computational Drug Signature apicidin, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB WAG000835 wnt signaling pathway Wnt family members are secreted glycoproteins who bind to cell surface receptors such as Frizzled. W (more detail) 25 NA Homo sapiens

BioCarta TAX001143 Genes annotated by the GO term GO:0003678. Catalysis of the unwinding of a DNA duplex. (more detail) 25 NA Homo sapiens

MSigDB TAX018302 GO:0014032 biological process neural crest cell development The process aimed at the progression of a neural crest cell over time, from initial commitment of th (more detail) 25 NA Homo sapiens

GOA WAG000030 IL12 signaling mediated by STAT4 (more detail) 25 NA Homo sapiens

NCI-Nature Curated IEI005593 Protein protein interactors of human gene GTF3C2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF3C2 (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D IEI009746 Protein protein interactors of human gene PELO from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PELO (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D IEI001416 Protein protein interactors of human gene BPTF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BPTF (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D IEI014302 Protein protein interactors of human gene TRMT2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRMT2A (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D IEI014001 Protein protein interactors of human gene TNFRSF10A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNFRSF10A (SwissProt (more detail) 27 17535438 Homo sapiens

I2D IEI003592 Protein protein interactors of human gene DLGAP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLGAP4 (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D IEI007806 Protein protein interactors of human gene MCPH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCPH1 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI005770 Protein protein interactors of human gene HEATR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HEATR1 (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D TAX027842 GO:0060349 biological process bone morphogenesis The process in which bones are generated and organized. (more detail) 27 NA Homo sapiens

GOA IEI003276 Protein protein interactors of human gene CYTH2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CYTH2 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI000970 Protein protein interactors of human gene ASCC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASCC3 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D TAX024862 GO:0044818 biological process mitotic G2/M transition checkpoint A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part (more detail) 27 NA Homo sapiens

GOA IEI004708 Protein protein interactors of human gene FER from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FER (SwissProt ID=P1 (more detail) 27 17535438 Homo sapiens

I2D MOX003915 Genes associated with Computational Drug Signature dacarbazine Genes associated with Computational Drug Signature dacarbazine, curated by the Drug Signature Databa (more detail) 27 25990557 Homo sapiens

DSigDB MEX002246 Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 27 25990557 Homo sapiens

DSigDB WIG001704 Toll Comparative Pathway Toll Comparative Pathway (more detail) 27 NA Homo sapiens

Protein Lounge WIG000773 Genes involved in CREB phosphorylation through the activation of Ras (more detail) 27 NA Homo sapiens

MSigDB WIG000307 Phospholipids as signalling intermediaries Sphingosine-1-phosphate (S1P) is an example of lipid messengers with both intracellular and extracel (more detail) 27 NA Homo sapiens

MSigDB MEX001616 Genes associated with Kinase Inhibitor AGN PC 087NKJ Genes associated with Kinase Inhibitor AGN-PC-087NKJ, curated by the Drug Signature Database (DSigDB (more detail) 27 25990557 Homo sapiens

DSigDB TAX000710 Genes annotated by the GO term GO:0001666. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. (more detail) 27 NA Homo sapiens

MSigDB WIG000223 Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. na (more detail) 27 NA Homo sapiens

MSigDB FOX000504 Genes in the cancer module 173 (more detail) 16 NA Homo sapiens

MSigDB MOX003367 Genes associated with Computational Drug Signature Lapatinib Genes associated with Computational Drug Signature Lapatinib, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB MOX002262 Genes associated with Computational Drug Signature Dracorhodin Genes associated with Computational Drug Signature Dracorhodin, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB TAX000693 Genes annotated by the GO term GO:0042129. Any process that modulates the frequency, rate or extent of T cell proliferation. (more detail) 16 NA Homo sapiens

MSigDB MOX002805 Genes associated with Computational Drug Signature Rimonabant hydrochloride Genes associated with Computational Drug Signature Rimonabant hydrochloride, curated by the Drug Sig (more detail) 16 25990557 Homo sapiens

DSigDB TAX015313 GO:0004675 molecular function transmembrane receptor protein serine/threonine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to in (more detail) 16 NA Homo sapiens

GOA FEX001747 Liver Semeus08 21genes Table 4. Gene expression profiling in HepG2 cells incubated with or without etoposide (e 50 M) for (more detail) 16 18366759 Homo sapiens

GeneSigDB MOX001007 Genes associated with Computational Drug Signature Brassinolide Genes associated with Computational Drug Signature Brassinolide, curated by the Drug Signature Datab (more detail) 16 25990557 Homo sapiens

DSigDB WIG002039 Serotonin Receptor 2 and ELK SRF/GATA4 signaling Serotonin Receptor 2 and ELK-SRF/GATA4 signaling (more detail) 16 NA Homo sapiens

WikiPathway TAX016914 GO:0007379 biological process segment specification The process in which segments assume individual identities; exemplified in insects by the actions of (more detail) 16 NA Homo sapiens

GOA TAX017087 GO:0008143 molecular function poly(A) binding Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, (more detail) 16 NA Homo sapiens

GOA WIG000268 B Cell Survival Pathway Physical interactions between intergrin alpha4beta1 heterodimer expressed on B cells and counter rec (more detail) 16 NA Homo sapiens

MSigDB FEX001680 Leukemia Messina10 16genes Table 4. PK Genes Specifically Expressed in B-NEG Patients Versus at Least 2 Other Groups (more detail) 16 20564080 Homo sapiens

GeneSigDB WIG000284 Cadmium induces DNA synthesis and proliferation in macrophages Exposure to divalent cadmium ions (Cd2+) is a known cancer risk factor, but the molecular mechanisms (more detail) 16 NA Homo sapiens

MSigDB MEX001310 Genes associated with Kinase Inhibitor Kinome 473 Genes associated with Kinase Inhibitor Kinome_473, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB MEX002341 Genes associated with Kinase Inhibitor GW806290X Genes associated with Kinase Inhibitor GW806290X, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB TAX016261 GO:0006337 biological process nucleosome disassembly The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin compo (more detail) 16 NA Homo sapiens

GOA TAX014041 GO:0002068 biological process glandular epithelial cell development The process whose specific outcome is the progression of a glandular epithelial cell over time, from (more detail) 16 NA Homo sapiens

GOA TAX015634 GO:0005159 molecular function insulin like growth factor receptor binding Interacting selectively and non-covalently with the insulin-like growth factor receptor. (more detail) 16 NA Homo sapiens

GOA FEX000887 Colon Grade06 20genes Table 1c. Expression and P values for most Wnt/B-catenin pathway genes (more detail) 16 16397240 Homo sapiens

GeneSigDB TAX000592 Genes annotated by the GO term GO:0009894. Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. (more detail) 16 NA Homo sapiens

MSigDB TAX001186 Genes annotated by the GO term GO:0004402. Catalysis of the reaction: acetyl CoA + histone = CoA + acetyl histone. (more detail) 16 NA Homo sapiens

MSigDB WIG002005 Complement Activation, Classical Pathway Complement Activation, Classical Pathway (more detail) 16 NA Homo sapiens

WikiPathway WIG000078 Hypoxic and oxygen homeostasis regulation of HIF 1 alpha (more detail) 16 NA Homo sapiens

MSigDB MOX006892 Genes associated with Computational Drug Signature ALDOSTERONE Genes associated with Computational Drug Signature ALDOSTERONE, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB TAX030388 GO:0090185 biological process negative regulation of kidney development Any process that decreases the rate, frequency or extent of kidney development. Kidney development i (more detail) 16 NA Homo sapiens

GOA TAX020758 GO:0031011 cellular component Ino80 complex A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activi (more detail) 16 NA Homo sapiens

GOA TAX029123 GO:0070822 cellular component Sin3 type complex Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core (more detail) 16 NA Homo sapiens

GOA IEI008935 Protein protein interactors of human gene NOL9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOL9 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D TAX022164 GO:0033599 biological process regulation of mammary gland epithelial cell proliferation Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferat (more detail) 16 NA Homo sapiens

GOA IEI010295 Protein protein interactors of human gene PPARGC1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPARGC1B (SwissProt (more detail) 16 17535438 Homo sapiens

I2D IEI005925 Protein protein interactors of human gene HNF4G from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNF4G (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI006976 Protein protein interactors of human gene KMT2E from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KMT2E (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX026308 GO:0048708 biological process astrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an astrocy (more detail) 16 NA Homo sapiens

GOA TAX020774 GO:0031050 biological process dsRNA fragmentation Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (genera (more detail) 16 NA Homo sapiens

GOA TAX028278 GO:0061050 biological process regulation of cell growth involved in cardiac muscle cell development Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, wh (more detail) 16 NA Homo sapiens

GOA TAX029186 GO:0070918 biological process production of small RNA involved in gene silencing by RNA The process in which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. R (more detail) 16 NA Homo sapiens

GOA IEI006954 Protein protein interactors of human gene KLK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLK2 (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D TAX022034 GO:0033202 cellular component DNA helicase complex A protein complex that possesses DNA helicase activity. (more detail) 16 NA Homo sapiens

GOA TAX034918 GO:2000773 biological process negative regulation of cellular senescence Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence. (more detail) 16 NA Homo sapiens

GOA IEI009029 Protein protein interactors of human gene NR2E1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR2E1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI005701 Protein protein interactors of human gene HAND2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HAND2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI004199 Protein protein interactors of human gene EPC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPC2 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI011033 Protein protein interactors of human gene RASL12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RASL12 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D TAX000229 Genes annotated by the GO term GO:0048732. The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. (more detail) 13 NA Homo sapiens

MSigDB TAX028337 GO:0061158 biological process 3' UTR mediated mRNA destabilization An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untr (more detail) 13 NA Homo sapiens

GOA TAX022938 GO:0035563 biological process positive regulation of chromatin binding Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is (more detail) 13 NA Homo sapiens

GOA TAX033554 GO:1904668 biological process positive regulation of ubiquitin protein ligase activity Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase ac (more detail) 13 NA Homo sapiens

GOA TAX015211 GO:0004535 molecular function poly(A) specific ribonuclease activity Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP. (more detail) 13 NA Homo sapiens

GOA IEI011783 Protein protein interactors of human gene SAMSN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SAMSN1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI005700 Protein protein interactors of human gene HAND1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HAND1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D FOX000704 Genes in the cancer module 407 (more detail) 13 NA Homo sapiens

MSigDB IEI010027 Protein protein interactors of human gene PLAGL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLAGL1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D WAG001011 p53 signaling pathway p53 is a transcription factor who's activity is regulated by phosphorylation. The function is p53 is (more detail) 13 NA Homo sapiens

BioCarta WAG000018 classical complement pathway The complement system is part of the defense against invading cells and is composed of about twenty (more detail) 13 NA Homo sapiens

BioCarta WIG000496 Circadian rhythm mammal (more detail) 13 NA Homo sapiens

MSigDB TAX022058 GO:0033262 biological process regulation of nuclear cell cycle DNA replication Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that o (more detail) 13 NA Homo sapiens

GOA TAX022798 GO:0035278 biological process miRNA mediated inhibition of translation The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once in (more detail) 13 NA Homo sapiens

GOA TAX016814 GO:0007171 biological process activation of transmembrane receptor protein tyrosine kinase activity Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kina (more detail) 13 NA Homo sapiens

GOA TAX025378 GO:0045974 biological process regulation of translation, ncRNA mediated Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mR (more detail) 13 NA Homo sapiens

GOA TAX033376 GO:1904294 biological process positive regulation of ERAD pathway Any process that activates or increases the frequency, rate or extent of ERAD pathway. (more detail) 13 NA Homo sapiens

GOA PEX001420 Pkinase C: Protein kinase C terminal domain (more detail) 13 NA Homo sapiens

Pfam FAX003056 GSEA KEGG Lung Cancer Tissue Explants (Extracellular Vesicles) RNA Degradation Top 3 KEGG pathways enriched in lung cancer tissue extract extracellular vesicle particles compared (more detail) 13 32795414 Homo sapiens

Cell TAX021472 GO:0032352 biological process positive regulation of hormone metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 13 NA Homo sapiens

GOA TAX023617 GO:0040033 biological process negative regulation of translation, ncRNA mediated Any process, mediated by small non-coding RNAs, that stops, prevents or reduces the rate that mRNAs (more detail) 13 NA Homo sapiens

GOA TAX017856 GO:0010092 biological process specification of animal organ identity The regionalization process in which the identity of an animal organ primordium is specified. Identi (more detail) 13 NA Homo sapiens

GOA TAX024372 GO:0043455 biological process regulation of secondary metabolic process Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical react (more detail) 13 NA Homo sapiens

GOA TAX026544 GO:0050713 biological process negative regulation of interleukin 1 beta secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release (more detail) 13 NA Homo sapiens

GOA TAX026562 GO:0050746 biological process regulation of lipoprotein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 13 NA Homo sapiens

GOA TAX033756 GO:1905038 biological process regulation of membrane lipid metabolic process Any process that modulates the frequency, rate or extent of membrane lipid metabolic process. (more detail) 13 NA Homo sapiens

GOA TAX032566 GO:1902571 biological process regulation of serine type peptidase activity Any process that modulates the frequency, rate or extent of serine-type peptidase activity. (more detail) 13 NA Homo sapiens

GOA WAG000832 mets affect on macrophage differentiation Termil differentiation of cells is often accompanied by repression of cellular proliferation, sugges (more detail) 13 NA Homo sapiens

BioCarta TAX001364 Genes annotated by the GO term GO:0016455. Functions to mediate the interaction of transcriptional activators with the RNA polymerase II general RNA polymerase II transcription factor complex. (more detail) 13 NA Homo sapiens

MSigDB MEX002041 Genes associated with Kinase Inhibitor Kinome 506 Genes associated with Kinase Inhibitor Kinome_506, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MOX002107 Genes associated with Computational Drug Signature O,P' DDE Genes associated with Computational Drug Signature O,P'-DDE, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens

DSigDB TAX029259 GO:0071025 biological process RNA surveillance The set of processes involved in identifying and degrading defective or aberrant RNAs. (more detail) 13 NA Homo sapiens

GOA TAX017974 GO:0010566 biological process regulation of ketone biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 13 NA Homo sapiens

GOA TAX024005 GO:0042762 biological process regulation of sulfur metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 13 NA Homo sapiens

GOA TAX025300 GO:0045836 biological process positive regulation of meiotic nuclear division Any process that activates or increases the frequency, rate or extent of meiosis. (more detail) 13 NA Homo sapiens

GOA TAX020651 GO:0030812 biological process negative regulation of nucleotide catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 13 NA Homo sapiens

GOA TAX025199 GO:0045651 biological process positive regulation of macrophage differentiation Any process that activates or increases the frequency, rate or extent of macrophage differentiation. (more detail) 13 NA Homo sapiens

GOA TAX033307 GO:1904152 biological process regulation of retrograde protein transport, ER to cytosol Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cyto (more detail) 13 NA Homo sapiens

GOA TAX031756 GO:1900003 biological process regulation of serine type endopeptidase activity Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity. (more detail) 13 NA Homo sapiens

GOA TAX032683 GO:1902894 biological process negative regulation of pri miRNA transcription by RNA polymerase II Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription (more detail) 13 NA Homo sapiens

GOA TAX034592 GO:2000303 biological process regulation of ceramide biosynthetic process Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process. (more detail) 13 NA Homo sapiens

GOA IEI009103 Protein protein interactors of human gene NT5DC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NT5DC2 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D TAX000009 Genes annotated by the GO term GO:0007257. The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK). (more detail) 13 NA Homo sapiens

MSigDB WIG001451 Classical Complement Pathway Classical Complement Pathway (more detail) 13 NA Homo sapiens

Protein Lounge TAX032045 GO:1901213 biological process regulation of transcription from RNA polymerase II promoter involved in heart development Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II (more detail) 13 NA Homo sapiens

GOA TAX030363 GO:0090153 biological process regulation of sphingolipid biosynthetic process Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid (more detail) 13 NA Homo sapiens

GOA TAX030746 GO:0097202 biological process activation of cysteine type endopeptidase activity Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase. (more detail) 13 NA Homo sapiens

GOA TAX026137 GO:0048302 biological process regulation of isotype switching to IgG isotypes Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes. (more detail) 13 NA Homo sapiens

GOA TAX033695 GO:1904923 biological process regulation of autophagy of mitochondrion in response to mitochondrial depolarization Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response t (more detail) 13 NA Homo sapiens

GOA TAX032700 GO:1902931 biological process negative regulation of alcohol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic pr (more detail) 13 NA Homo sapiens

GOA TAX027872 GO:0060389 biological process pathway restricted SMAD protein phosphorylation The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway rest (more detail) 13 NA Homo sapiens

GOA PEX001814 Ets: Ets domain (more detail) 13 NA Homo sapiens

Pfam IEI008937 Protein protein interactors of human gene NOM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOM1 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI003322 Protein protein interactors of human gene DBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DBP (SwissProt ID=Q1 (more detail) 13 17535438 Homo sapiens

I2D WAG001467 nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells RXR and RAR are nuclear receptors that bind either all trans retinoic (tRA) or 9cis retinoic acid (9 (more detail) 13 NA Homo sapiens

BioCarta MOX005546 Genes associated with Computational Drug Signature 1H Pyrrole 2,5 dione, 3,4 diphenyl Genes associated with Computational Drug Signature 1H-Pyrrole-2,5-dione, 3,4-diphenyl-, curated by t (more detail) 13 25990557 Homo sapiens

DSigDB TAX029076 GO:0070696 molecular function transmembrane receptor protein serine/threonine kinase binding Interacting selectively and non-covalently with a receptor that spans a cell membrane and possesses (more detail) 13 NA Homo sapiens

GOA TAX019337 GO:0017017 molecular function MAP kinase tyrosine/serine/threonine phosphatase activity Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/ (more detail) 13 NA Homo sapiens

GOA TAX022265 GO:0033962 biological process cytoplasmic mRNA processing body assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmi (more detail) 13 NA Homo sapiens

GOA TAX033633 GO:1904814 biological process regulation of protein localization to chromosome, telomeric region Any process that modulates the frequency, rate or extent of protein localization to chromosome, telo (more detail) 13 NA Homo sapiens

GOA TAX033375 GO:1904293 biological process negative regulation of ERAD pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway. (more detail) 13 NA Homo sapiens

GOA TAX028654 GO:0062009 biological process secondary palate development The biological process whose specific outcome is the progression of the secondary palate from an ini (more detail) 13 NA Homo sapiens

GOA IEI008635 Protein protein interactors of human gene NCOA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCOA4 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D WIG000275 Transcription Regulation by Methyltransferase of CARM1 Several forms of post-translational modification regulate protein activities. Recently, protein meth (more detail) 13 NA Homo sapiens

MSigDB MOX005545 Genes associated with Computational Drug Signature 1H Pyrrole 2,5 dione, 3,4 bis(4 methoxyphenyl) Genes associated with Computational Drug Signature 1H-Pyrrole-2,5-dione, 3,4-bis(4-methoxyphenyl)-, (more detail) 13 25990557 Homo sapiens

DSigDB MOX006679 Genes associated with Computational Drug Signature AGN PC 00BUNE Genes associated with Computational Drug Signature AGN-PC-00BUNE, curated by the Drug Signature Data (more detail) 13 25990557 Homo sapiens

DSigDB TAX001336 Genes annotated by the GO term GO:0008601. Modulation of the activity of the enzyme protein phosphatase type 2A. (more detail) 13 NA Homo sapiens

MSigDB WIG001916 Cell Differentiation Index Cell Differentiation - Index (more detail) 13 NA Homo sapiens

WikiPathway TAX013532 GO:0000900 molecular function translation repressor activity, mRNA regulatory element binding Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through (more detail) 13 NA Homo sapiens

GOA TAX023952 GO:0042659 biological process regulation of cell fate specification Any process that mediates the adoption of a specific fate by a cell. (more detail) 13 NA Homo sapiens

GOA TAX026868 GO:0051198 biological process negative regulation of coenzyme metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 13 NA Homo sapiens

GOA IEI001753 Protein protein interactors of human gene CAMKK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAMKK1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D TAX024187 GO:0043153 biological process entrainment of circadian clock by photoperiod The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and (more detail) 18 NA Homo sapiens

GOA IEI015212 Protein protein interactors of human gene ZBTB33 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB33 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI013354 Protein protein interactors of human gene TAF6L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF6L (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D TAX029506 GO:0071498 biological process cellular response to fluid shear stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 18 NA Homo sapiens

GOA TAX033661 GO:1904872 biological process regulation of telomerase RNA localization to Cajal body Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal bod (more detail) 18 NA Homo sapiens

GOA IEI008946 Protein protein interactors of human gene NOP53 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOP53 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D TAX026314 GO:0048714 biological process positive regulation of oligodendrocyte differentiation Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentia (more detail) 18 NA Homo sapiens

GOA IEI007149 Protein protein interactors of human gene LARP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LARP4 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D TAX032839 GO:1903206 biological process negative regulation of hydrogen peroxide induced cell death Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induc (more detail) 18 NA Homo sapiens

GOA IEI008783 Protein protein interactors of human gene NFATC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFATC3 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI009752 Protein protein interactors of human gene PER2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PER2 (SwissProt ID=O (more detail) 18 17535438 Homo sapiens

I2D TAX021448 GO:0032303 biological process regulation of icosanoid secretion Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid f (more detail) 18 NA Homo sapiens

GOA TAX035024 GO:2001039 biological process negative regulation of cellular response to drug Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to dr (more detail) 18 NA Homo sapiens

GOA TAX031992 GO:1901032 biological process negative regulation of response to reactive oxygen species Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive ox (more detail) 18 NA Homo sapiens

GOA TAX029415 GO:0071371 biological process cellular response to gonadotropin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 18 NA Homo sapiens

GOA IEI004092 Protein protein interactors of human gene ELL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELL2 (SwissProt ID=O (more detail) 18 17535438 Homo sapiens

I2D MEX002201 Genes associated with Kinase Inhibitor 405554 55 4 Genes associated with Kinase Inhibitor 405554-55-4, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB WIG000387 Nerve growth factor pathway (NGF) Nerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and prolifera (more detail) 18 NA Homo sapiens

MSigDB PEX000443 BTB: BTB/POZ domain The BTB (for BR-C, ttk and bab) 1 or POZ (for Pox virus and Zinc finger) 2 domain is present near th (more detail) 18 NA Homo sapiens

Pfam MOX015872 Genes associated with Computational Drug Signature Vorinostat Genes associated with Computational Drug Signature Vorinostat, curated by the Drug Signature Databas (more detail) 18 25990557 Homo sapiens

DSigDB TAX014158 GO:0002287 biological process alpha beta T cell activation involved in immune response The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, (more detail) 18 NA Homo sapiens

GOA WAG000628 atm signaling pathway The ataxia telangiectasia-mutated gene (ATM) encodes a protein kise that acts as a tumor suppressor. (more detail) 18 NA Homo sapiens

BioCarta WIG000413 PTEN dependent cell cycle arrest and apoptosis PTEN is a tumor suppressor gene. Recombinant PTEN is capable of dephosphorylating phosphatidylinosit (more detail) 18 NA Homo sapiens

MSigDB WIG000824 Genes involved in Energy dependent regulation of mTOR by LKB1 AMPK (more detail) 18 NA Homo sapiens

MSigDB MOX001960 Genes associated with Computational Drug Signature Ginsenoside Re Genes associated with Computational Drug Signature Ginsenoside Re, curated by the Drug Signature Dat (more detail) 18 25990557 Homo sapiens

DSigDB MOX013298 Genes associated with Computational Drug Signature KN 62 Genes associated with Computational Drug Signature KN-62, curated by the Drug Signature Database (DS (more detail) 18 25990557 Homo sapiens

DSigDB TAX014161 GO:0002293 biological process alpha beta T cell differentiation involved in immune response The process in which an antigenically naive alpha-beta T cell acquires the specialized features of a (more detail) 18 NA Homo sapiens

GOA MEX002371 Genes associated with Kinase Inhibitor Kinome 454 Genes associated with Kinase Inhibitor Kinome_454, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB WIG000853 Genes involved in G1/S Specific Transcription (more detail) 18 NA Homo sapiens

MSigDB WIG001164 Genes involved in RIP mediated NFkB activation via DAI (more detail) 18 NA Homo sapiens

MSigDB MEX002032 Genes associated with Kinase Inhibitor Syk Inhibitor II Genes associated with Kinase Inhibitor Syk Inhibitor II, curated by the Drug Signature Database (DSi (more detail) 18 25990557 Homo sapiens

DSigDB MOX003248 Genes associated with Computational Drug Signature alvespimycin Genes associated with Computational Drug Signature alvespimycin, curated by the Drug Signature Datab (more detail) 18 25990557 Homo sapiens

DSigDB TAX014509 GO:0002902 biological process regulation of B cell apoptotic process Any process that modulates the frequency, rate, or extent of B cell apoptotic process. (more detail) 18 NA Homo sapiens

GOA TAX018099 GO:0010758 biological process regulation of macrophage chemotaxis Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemot (more detail) 18 NA Homo sapiens

GOA TAX014619 GO:0003180 biological process aortic valve morphogenesis The process in which the structure of the aortic valve is generated and organized. (more detail) 18 NA Homo sapiens

GOA TAX015857 GO:0005665 cellular component RNA polymerase II, core complex RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a m (more detail) 18 NA Homo sapiens

GOA MOX006548 Genes associated with Computational Drug Signature AC1LEORR Genes associated with Computational Drug Signature AC1LEORR, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB IEI009429 Protein protein interactors of human gene PACRG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PACRG (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI011831 Protein protein interactors of human gene SCAND1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCAND1 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI004198 Protein protein interactors of human gene EPC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPC1 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI002559 Protein protein interactors of human gene CILK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CILK1 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI008732 Protein protein interactors of human gene NEK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEK1 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D TAX025756 GO:0046827 biological process positive regulation of protein export from nucleus Any process that activates or increases the frequency, rate or extent of directed movement of protei (more detail) 20 NA Homo sapiens

GOA IEI003720 Protein protein interactors of human gene DOCK5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DOCK5 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX024131 GO:0043046 biological process DNA methylation involved in gamete generation The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of (more detail) 20 NA Homo sapiens

GOA TAX027996 GO:0060563 biological process neuroepithelial cell differentiation The process in which epiblast cells acquire specialized features of neuroepithelial cells. (more detail) 20 NA Homo sapiens

GOA TAX027873 GO:0060390 biological process regulation of SMAD protein signal transduction Any process that modulates the rate, frequency or extent of SMAD protein signal transduction. Pathwa (more detail) 20 NA Homo sapiens

GOA TAX018270 GO:0010984 biological process regulation of lipoprotein particle clearance Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipopro (more detail) 20 NA Homo sapiens

GOA IEI006402 Protein protein interactors of human gene INO80B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INO80B (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI014318 Protein protein interactors of human gene TRPC4AP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRPC4AP (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D IEI007571 Protein protein interactors of human gene MAFB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAFB (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI013357 Protein protein interactors of human gene TAF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF8 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D WIG001749 MNAR/PELP1 and Estrogen Receptor Interaction MNAR/PELP1 and Estrogen Receptor Interaction (more detail) 20 NA Homo sapiens

Protein Lounge MOX012699 Genes associated with Computational Drug Signature Flavopiridol hydrochloride Genes associated with Computational Drug Signature Flavopiridol hydrochloride, curated by the Drug S (more detail) 20 25990557 Homo sapiens

DSigDB TAX013885 GO:0001848 molecular function complement binding Interacting selectively and non-covalently with any component or product of the complement cascade. (more detail) 20 NA Homo sapiens

GOA WAG001006 tpo signaling pathway Thrombopoietin (TPO) binds to its receptor inducing aggregation and activation. TPO sigls its growth (more detail) 20 NA Homo sapiens

BioCarta WIG001135 Genes involved in Regulation of gene expression in beta cells (more detail) 20 NA Homo sapiens

MSigDB MEX001208 Genes associated with Kinase Inhibitor gw5074 Genes associated with Kinase Inhibitor gw5074, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens

DSigDB WIG000825 Genes involved in eNOS activation and regulation (more detail) 20 NA Homo sapiens

MSigDB MOX013772 Genes associated with Computational Drug Signature Molephantinin Genes associated with Computational Drug Signature Molephantinin, curated by the Drug Signature Data (more detail) 20 25990557 Homo sapiens

DSigDB MEX001606 Genes associated with Kinase Inhibitor Lck Inhibitor Genes associated with Kinase Inhibitor Lck Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 20 25990557 Homo sapiens

DSigDB MEX001484 Genes associated with Kinase Inhibitor Kinome 511 Genes associated with Kinase Inhibitor Kinome_511, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens

DSigDB FOX000839 Genes in the cancer module 81 (more detail) 20 NA Homo sapiens

MSigDB MEX001585 Genes associated with Kinase Inhibitor NCGC00346963 01 Genes associated with Kinase Inhibitor NCGC00346963-01, curated by the Drug Signature Database (DSig (more detail) 20 25990557 Homo sapiens

DSigDB TAX000261 Genes annotated by the GO term GO:0048872. The biological processes involved in the maintenance of the equilibrium of cell number within a population of cells. (more detail) 20 NA Homo sapiens

MSigDB WIG001813 Cardiomyocyte Differentiation through BMP Receptors Cardiomyocyte Differentiation through BMP Receptors (more detail) 20 NA Homo sapiens

Protein Lounge WAG000237 fas signaling pathway (cd95) Ras activates many sigling cascades. Here we illustrate some of the well-characterized cascades in (more detail) 20 NA Homo sapiens

BioCarta FEX002198 Lymphoma Qiu03 42genes Table 1 General ALL markers; A total of 39 genes among which four were unknown were expressed in e (more detail) 20 12970791 Homo sapiens

GeneSigDB IEI008148 Protein protein interactors of human gene MPRIP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MPRIP (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI006319 Protein protein interactors of human gene IL1R1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL1R1 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D TAX026628 GO:0050849 biological process negative regulation of calcium mediated signaling Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signa (more detail) 28 NA Homo sapiens

GOA IEI001206 Protein protein interactors of human gene BACE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BACE1 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI006401 Protein protein interactors of human gene INO80 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INO80 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D TAX031802 GO:1900087 biological process positive regulation of G1/S transition of mitotic cell cycle Any cell cycle regulatory process that promotes the commitment of a cell from G1 to S phase of the m (more detail) 28 NA Homo sapiens

GOA TAX022619 GO:0034698 biological process response to gonadotropin Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 28 NA Homo sapiens

GOA IEI002126 Protein protein interactors of human gene CD36 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CD36 (SwissProt ID=P (more detail) 28 17535438 Homo sapiens

I2D TAX032927 GO:1903393 biological process positive regulation of adherens junction organization Any process that activates or increases the frequency, rate or extent of adherens junction organizat (more detail) 28 NA Homo sapiens

GOA IEI011036 Protein protein interactors of human gene RASSF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RASSF2 (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D IEI005730 Protein protein interactors of human gene HBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HBP1 (SwissProt ID=O (more detail) 28 17535438 Homo sapiens

I2D IEI006337 Protein protein interactors of human gene IL24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL24 (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI014074 Protein protein interactors of human gene TOM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TOM1 (SwissProt ID=O (more detail) 28 17535438 Homo sapiens

I2D IEI003167 Protein protein interactors of human gene CUX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUX1 (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D MEX000942 Genes associated with Approved Drug methysergide maleate Genes associated with Approved Drug methysergide maleate, curated by the Drug Signature Database (DS (more detail) 28 25990557 Homo sapiens

DSigDB WIG001341 Anti diabetic Drug Potassium Channel Inhibitors Pathway, Pharmacodynamics Representation of anti-diabetic drugs repaglinide, nateglinide and sulfonylurea effects on insulin s (more detail) 28 NA Homo sapiens

PharmGKB TAX015852 GO:0005657 cellular component replication fork The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands (more detail) 28 NA Homo sapiens

GOA FEX001807 Lung Carson04 50genes Increase Table 1a. Largest fold increase genes following camptothecin treatment of HeLa cells (more detail) 28 15026349 Homo sapiens

GeneSigDB TAX001145 Genes annotated by the GO term GO:0003690. Interacting selectively with double stranded DNA. (more detail) 28 NA Homo sapiens

MSigDB WIG001191 Genes involved in SHC mediated cascade (more detail) 28 NA Homo sapiens

MSigDB WAG000625 phospholipids as signalling intermediaries Sphingosine-1-phosphate (S1P) is an example of lipid messengers with both intracellular and extracel (more detail) 28 NA Homo sapiens

BioCarta WIG000024 BARD1 signaling events (more detail) 28 NA Homo sapiens

MSigDB FEX000853 Colon Koehler04 29genes Table 2. Up-regulated transcripts with statistical significance in the tumour/metastasis group compa (more detail) 28 15307139 Homo sapiens

GeneSigDB IEI011475 Protein protein interactors of human gene RORB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RORB (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI011900 Protein protein interactors of human gene SDC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SDC4 (SwissProt ID=P (more detail) 22 17535438 Homo sapiens

I2D IEI007831 Protein protein interactors of human gene MEAF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEAF6 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI002977 Protein protein interactors of human gene CREBZF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CREBZF (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D TAX025752 GO:0046823 biological process negative regulation of nucleocytoplasmic transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement (more detail) 22 NA Homo sapiens

GOA IEI008745 Protein protein interactors of human gene NELFE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NELFE (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D TAX028420 GO:0061384 biological process heart trabecula morphogenesis The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue e (more detail) 22 NA Homo sapiens

GOA IEI002028 Protein protein interactors of human gene CCN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCN2 (SwissProt ID=P (more detail) 22 17535438 Homo sapiens

I2D TAX032630 GO:1902742 biological process apoptotic process involved in development Any apoptotic process that is involved in anatomical structure development. (more detail) 22 NA Homo sapiens

GOA TAX029088 GO:0070723 biological process response to cholesterol Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 22 NA Homo sapiens

GOA TAX015633 GO:0005158 molecular function insulin receptor binding Interacting selectively and non-covalently with the insulin receptor. (more detail) 22 NA Homo sapiens

GOA TAX018422 GO:0014897 biological process striated muscle hypertrophy The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells (more detail) 22 NA Homo sapiens

GOA MOX004790 Genes associated with Computational Drug Signature triamterene Genes associated with Computational Drug Signature triamterene, curated by the Drug Signature Databa (more detail) 22 25990557 Homo sapiens

DSigDB FEX000129 Brain Watson02 24genes Table 2. GenBank Accession Number Gene Name and Reported Chromosomal Localization of Gene Transcri (more detail) 22 12163391 Homo sapiens

GeneSigDB TAX001141 Genes annotated by the GO term GO:0008094. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single or double stranded DNA; drives another reaction. (more detail) 22 NA Homo sapiens

MSigDB MEX000955 Genes associated with Approved Drug isotretinoin Genes associated with Approved Drug isotretinoin, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB MOX001078 Genes associated with Computational Drug Signature 3 aminobenzamide Genes associated with Computational Drug Signature 3-aminobenzamide, curated by the Drug Signature D (more detail) 22 25990557 Homo sapiens

DSigDB MOX002228 Genes associated with Computational Drug Signature calyculin A Genes associated with Computational Drug Signature calyculin A, curated by the Drug Signature Databa (more detail) 22 25990557 Homo sapiens

DSigDB TAX013824 GO:0001773 biological process myeloid dendritic cell activation The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, che (more detail) 22 NA Homo sapiens

GOA MEX001895 Genes associated with Kinase Inhibitor Motesanib Genes associated with Kinase Inhibitor Motesanib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB TAX018432 GO:0014912 biological process negative regulation of smooth muscle cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell mig (more detail) 22 NA Homo sapiens

GOA MEX002410 Genes associated with Kinase Inhibitor Gefitinib Genes associated with Kinase Inhibitor Gefitinib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB WAG001069 PDGFR alpha signaling pathway (more detail) 22 NA Homo sapiens

NCI-Nature Curated MOX003623 Genes associated with Computational Drug Signature Muramyl Dipeptide Genes associated with Computational Drug Signature Muramyl Dipeptide, curated by the Drug Signature (more detail) 22 25990557 Homo sapiens

DSigDB MOX004033 Genes associated with Computational Drug Signature Quinomycin A Genes associated with Computational Drug Signature Quinomycin A, curated by the Drug Signature Datab (more detail) 22 25990557 Homo sapiens

DSigDB MAX000475 Cancer related genes down regulated in any of four hepatoma cell lines following 24 h treatment with TSA [PubChem=5562]. OBJECTIVE: Histone deacetylase (HDAC) inhibitors have been reported to induce cell growth arrest, ap (more detail) 22 NA Homo sapiens

MSigDB MEX001396 Genes associated with Kinase Inhibitor Gefitinib Genes associated with Kinase Inhibitor Gefitinib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB TAX026309 GO:0048709 biological process oligodendrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an oligode (more detail) 26 NA Homo sapiens

GOA IEI012745 Protein protein interactors of human gene SOCS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOCS2 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI006131 Protein protein interactors of human gene IARS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IARS2 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D TAX019882 GO:0019915 biological process lipid storage The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvent (more detail) 26 NA Homo sapiens

GOA TAX029183 GO:0070911 biological process global genome nucleotide excision repair The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands (more detail) 26 NA Homo sapiens

GOA TAX028869 GO:0070325 molecular function lipoprotein particle receptor binding Interacting selectively and non-covalently with a lipoprotein particle receptor. (more detail) 26 NA Homo sapiens

GOA IEI013352 Protein protein interactors of human gene TAF5L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF5L (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI000774 Protein protein interactors of human gene AQR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AQR (SwissProt ID=O6 (more detail) 26 17535438 Homo sapiens

I2D IEI009020 Protein protein interactors of human gene NR1D2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR1D2 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI008727 Protein protein interactors of human gene NEFM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEFM (SwissProt ID=P (more detail) 26 17535438 Homo sapiens

I2D IEI006974 Protein protein interactors of human gene KMT2C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KMT2C (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D MAX000648 The lung adenocarcinoma TSP (tumor sequencing project) genes that were found significantly mutated by at least one method. Determining the genetic basis of cancer requires comprehensive analyses of large collections of hist (more detail) 26 NA Homo sapiens

MSigDB MOX002742 Genes associated with Computational Drug Signature Wogonin Genes associated with Computational Drug Signature Wogonin, curated by the Drug Signature Database ( (more detail) 26 25990557 Homo sapiens

DSigDB WIG001007 Genes involved in Myogenesis (more detail) 26 NA Homo sapiens

MSigDB MOX003870 Genes associated with Computational Drug Signature clomiphene Genes associated with Computational Drug Signature clomiphene, curated by the Drug Signature Databas (more detail) 26 25990557 Homo sapiens

DSigDB MEX004072 Genes associated with Perturbagen Signature rimexolone Genes associated with Perturbagen Signature rimexolone, curated by the Drug Signature Database (DSig (more detail) 26 25990557 Homo sapiens

DSigDB TAX018103 GO:0010762 biological process regulation of fibroblast migration Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast ce (more detail) 26 NA Homo sapiens

GOA WAG000442 VEGFR1 specific signals (more detail) 26 NA Homo sapiens

NCI-Nature Curated TAX000128 Genes annotated by the GO term GO:0006333. The formation or destruction of chromatin structures. (more detail) 26 NA Homo sapiens

MSigDB TAX015592 GO:0005104 molecular function fibroblast growth factor receptor binding Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR). (more detail) 26 NA Homo sapiens

GOA MOX013270 Genes associated with Computational Drug Signature kenpaullone Genes associated with Computational Drug Signature kenpaullone, curated by the Drug Signature Databa (more detail) 26 25990557 Homo sapiens

DSigDB MOX003688 Genes associated with Computational Drug Signature Antimycin A Genes associated with Computational Drug Signature Antimycin A, curated by the Drug Signature Databa (more detail) 26 25990557 Homo sapiens

DSigDB MEX002195 Genes associated with Kinase Inhibitor BX 912 Genes associated with Kinase Inhibitor BX-912, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens

DSigDB WAG001237 role of egf receptor transactivation by gpcrs in cardiac hypertrophy One of responses to increased blood pressure is cardiac hypertrophy through increased size of ventri (more detail) 26 NA Homo sapiens

BioCarta FEX001003 EmbryonicStemCell Xu09 26genes Table S8b.cardiac-enriched genes involved in functional categories; this table refers to genes in PP (more detail) 26 19658189 Homo sapiens

GeneSigDB IEI009356 Protein protein interactors of human gene OSGIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OSGIN1 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D IEI004280 Protein protein interactors of human gene ERN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERN1 (SwissProt ID=O (more detail) 24 17535438 Homo sapiens

I2D IEI010560 Protein protein interactors of human gene PRR20A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRR20A (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D TAX025220 GO:0045672 biological process positive regulation of osteoclast differentiation Any process that activates or increases the frequency, rate or extent of osteoclast differentiation. (more detail) 24 NA Homo sapiens

GOA IEI013711 Protein protein interactors of human gene TIMELESS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TIMELESS (SwissProt (more detail) 24 17535438 Homo sapiens

I2D IEI001019 Protein protein interactors of human gene ATF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATF6 (SwissProt ID=P (more detail) 24 17535438 Homo sapiens

I2D IEI005724 Protein protein interactors of human gene HBB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HBB (SwissProt ID=P6 (more detail) 24 17535438 Homo sapiens

I2D IEI002460 Protein protein interactors of human gene CHD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD1 (SwissProt ID=O (more detail) 24 17535438 Homo sapiens

I2D TAX021569 GO:0032461 biological process positive regulation of protein oligomerization Any process that activates or increases the frequency, rate or extent of protein oligomerization. (more detail) 24 NA Homo sapiens

GOA TAX021751 GO:0032753 biological process positive regulation of interleukin 4 production Any process that activates or increases the frequency, rate, or extent of interleukin-4 production. (more detail) 24 NA Homo sapiens

GOA IEI006955 Protein protein interactors of human gene KLK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLK3 (SwissProt ID=P (more detail) 24 17535438 Homo sapiens

I2D IEI006767 Protein protein interactors of human gene KDM5C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM5C (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D TAX023016 GO:0035666 biological process TRIF dependent toll like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where (more detail) 24 NA Homo sapiens

GOA IEI004760 Protein protein interactors of human gene FGG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FGG (SwissProt ID=P0 (more detail) 24 17535438 Homo sapiens

I2D MOX012888 Genes associated with Computational Drug Signature GNF PF 2893 Genes associated with Computational Drug Signature GNF-PF-2893, curated by the Drug Signature Databa (more detail) 24 25990557 Homo sapiens

DSigDB MOX004085 Genes associated with Computational Drug Signature fenbendazole Genes associated with Computational Drug Signature fenbendazole, curated by the Drug Signature Datab (more detail) 24 25990557 Homo sapiens

DSigDB TAX000503 Genes annotated by the GO term GO:0051251. Any process that activates or increases the frequency, rate or extent of lymphocyte activation. (more detail) 24 NA Homo sapiens

MSigDB MEX000871 Genes associated with Approved Drug dactinomycin Genes associated with Approved Drug dactinomycin, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB MOX004872 Genes associated with Computational Drug Signature 2,6 DICHLOROINDOPHENOL Genes associated with Computational Drug Signature 2,6-DICHLOROINDOPHENOL, curated by the Drug Signa (more detail) 24 25990557 Homo sapiens

DSigDB MOX003046 Genes associated with Computational Drug Signature Fludioxonil Genes associated with Computational Drug Signature Fludioxonil, curated by the Drug Signature Databa (more detail) 24 25990557 Homo sapiens

DSigDB TAX015564 GO:0005035 molecular function death receptor activity Combining with an extracellular messenger (called a death ligand), and transmitting the signal from (more detail) 24 NA Homo sapiens

GOA TAX018416 GO:0014888 biological process striated muscle adaptation Any process in which striated muscle adapts, with consequent modifications to structural and/or func (more detail) 24 NA Homo sapiens

GOA WIG001138 Genes involved in Regulation of IFNA signaling (more detail) 24 NA Homo sapiens

MSigDB MEX001535 Genes associated with Kinase Inhibitor go 7874 Genes associated with Kinase Inhibitor go 7874, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB TAX014180 GO:0002323 biological process natural killer cell activation involved in immune response The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, c (more detail) 24 NA Homo sapiens

GOA MOX005801 Genes associated with Computational Drug Signature 3,4 dichloroisocoumarin Genes associated with Computational Drug Signature 3,4-dichloroisocoumarin, curated by the Drug Sign (more detail) 24 25990557 Homo sapiens

DSigDB FEX010385 hsa miR 4278 HITS-CLIP, Functional MTI (Weak) (more detail) 24 NA Homo sapiens

mirTARbase MEX001309 Genes associated with Kinase Inhibitor CHEMBL552425 Genes associated with Kinase Inhibitor CHEMBL552425, curated by the Drug Signature Database (DSigDB) (more detail) 24 25990557 Homo sapiens

DSigDB TAX015562 GO:0005031 molecular function tumor necrosis factor activated receptor activity Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophag (more detail) 24 NA Homo sapiens

GOA MOX004722 Genes associated with Computational Drug Signature teniposide Genes associated with Computational Drug Signature teniposide, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens

DSigDB FEX000271 Breast Treff04 15genes HMGA1 Table 2. Pathway-associated genes regulated by HMGA1 (more detail) 15 14737112 Homo sapiens

GeneSigDB FEX000513 Breast Albrektsen07 16genes Table 3 Genes regulated by factor VIIa (FVIIa) (P (more detail) 15 17470200 Homo sapiens

GeneSigDB TAX029099 GO:0070742 molecular function C2H2 zinc finger domain binding Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H (more detail) 15 NA Homo sapiens

GOA TAX020095 GO:0021879 biological process forebrain neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron that (more detail) 15 NA Homo sapiens

GOA IEI002058 Protein protein interactors of human gene CCNT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNT2 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI002498 Protein protein interactors of human gene CHN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHN1 (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D WAG000664 Regulation of p38 alpha and p38 beta (more detail) 15 NA Homo sapiens

NCI-Nature Curated FEX000209 Brain Katsel08 17genes Table 4. Differentially Expressed Cell Cycle Genes in 15 Brain Regions in SZ. The t-scores were calc (more detail) 15 18322470 Homo sapiens

GeneSigDB WIG000318 Erythrocyte Differentiation Pathway Stem cells in the bone marrow produce a variety of hematopoietic cell types from common progenitor c (more detail) 15 NA Homo sapiens

MSigDB MEX002180 Genes associated with Kinase Inhibitor Alsterpaullone, 2 Cyanoethyl Genes associated with Kinase Inhibitor Alsterpaullone, 2-Cyanoethyl, curated by the Drug Signature D (more detail) 15 25990557 Homo sapiens

DSigDB MEX004086 Genes associated with Perturbagen Signature rottlerin Genes associated with Perturbagen Signature rottlerin, curated by the Drug Signature Database (DSigD (more detail) 15 25990557 Homo sapiens

DSigDB TAX020709 GO:0030902 biological process hindbrain development The process whose specific outcome is the progression of the hindbrain over time, from its formation (more detail) 15 NA Homo sapiens

GOA TAX027892 GO:0060413 biological process atrial septum morphogenesis The developmental process in which atrial septum is generated and organized. The atrial septum separ (more detail) 15 NA Homo sapiens

GOA TAX028783 GO:0070182 molecular function DNA polymerase binding Interacting selectively and non-covalently with a DNA polymerase. (more detail) 15 NA Homo sapiens

GOA MOX017561 Genes associated with Computational Drug Signature temephos Genes associated with Computational Drug Signature temephos, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB IEI012616 Protein protein interactors of human gene SMG6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMG6 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI006162 Protein protein interactors of human gene IER3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IER3 (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D IEI006299 Protein protein interactors of human gene IL13RA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL13RA2 (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D WIG000369 The IGF 1 Receptor and Longevity A demonstrated means to increase lifespan in a wide range of organisms is through the restriction of (more detail) 15 NA Homo sapiens

MSigDB FOX000446 Genes in the cancer module 116 (more detail) 15 NA Homo sapiens

MSigDB MOX002470 Genes associated with Computational Drug Signature Homocastasterone Genes associated with Computational Drug Signature Homocastasterone, curated by the Drug Signature D (more detail) 15 25990557 Homo sapiens

DSigDB TAX035015 GO:2001028 biological process positive regulation of endothelial cell chemotaxis Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis (more detail) 15 NA Homo sapiens

GOA TAX027899 GO:0060425 biological process lung morphogenesis The process in which the anatomical structures of the lung are generated and organized. (more detail) 15 NA Homo sapiens

GOA IEI005652 Protein protein interactors of human gene H2AC21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AC21 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D MOX003333 Genes associated with Computational Drug Signature propanil Genes associated with Computational Drug Signature propanil, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB TAX019069 GO:0016514 cellular component SWI/SNF complex A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconser (more detail) 15 NA Homo sapiens

GOA IEI003567 Protein protein interactors of human gene DIRAS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIRAS3 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D WIG000060 Validated nuclear estrogen receptor beta network (more detail) 15 NA Homo sapiens

MSigDB TAX020666 GO:0030852 biological process regulation of granulocyte differentiation Any process that modulates the frequency, rate or extent of granulocyte differentiation. (more detail) 15 NA Homo sapiens

GOA IEI003156 Protein protein interactors of human gene CUEDC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUEDC2 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D WAG000842 gata3 participate in activating the th2 cytokine genes expression CD4+ helper T cells differentiate into distinct subtypes, Th1 and Th2 cells. Th2 cells are involved (more detail) 15 NA Homo sapiens

BioCarta WIG000344 Stress Induction of HSP Regulation Mammalian cells can respond to a variety of stresses such as heat, cold, oxidative stress, metabolic (more detail) 15 NA Homo sapiens

MSigDB GEX001539 stomach neoplasms stomach neoplasms associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 15 NA Homo sapiens

GAD PEX000618 TGF beta: Transforming growth factor beta like domain (more detail) 15 NA Homo sapiens

Pfam MAX001756 Genes whose transcription is down regulated by histone deacetylase inhibitors. The path to the discovery of suberoylanilide hydroxamic acid (SAHA, vorinostat) began over three dec (more detail) 15 NA Homo sapiens

MSigDB MOX000439 Genes associated with Computational Drug Signature Surfactin Genes associated with Computational Drug Signature Surfactin, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB PEX002587 Chromo: Chromo (CHRromatin Organisation MOdifier) domain (more detail) 15 NA Homo sapiens

Pfam MEX003984 Genes associated with Perturbagen Signature profenamine Genes associated with Perturbagen Signature profenamine, curated by the Drug Signature Database (DSi (more detail) 15 25990557 Homo sapiens

DSigDB TAX028916 GO:0070410 molecular function co SMAD binding Interacting selectively and non-covalently with a common mediator SMAD signaling protein. (more detail) 12 NA Homo sapiens

GOA IEI009423 Protein protein interactors of human gene PABPC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PABPC3 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D TAX032243 GO:1901722 biological process regulation of cell proliferation involved in kidney development Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney de (more detail) 12 NA Homo sapiens

GOA IEI006017 Protein protein interactors of human gene HR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HR (SwissProt ID=O43 (more detail) 12 17535438 Homo sapiens

I2D IEI000521 Protein protein interactors of human gene ALX4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ALX4 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI007392 Protein protein interactors of human gene LRIG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRIG1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX024533 GO:0043922 biological process negative regulation by host of viral transcription Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of vi (more detail) 12 NA Homo sapiens

GOA TAX024894 GO:0045019 biological process negative regulation of nitric oxide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 12 NA Homo sapiens

GOA TAX033763 GO:1905048 biological process regulation of metallopeptidase activity Any process that modulates the frequency, rate or extent of metallopeptidase activity. (more detail) 12 NA Homo sapiens

GOA IEI004090 Protein protein interactors of human gene ELK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELK4 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D TAX030745 GO:0097201 biological process negative regulation of transcription from RNA polymerase II promoter in response to stress Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II (more detail) 12 NA Homo sapiens

GOA TAX024941 GO:0045086 biological process positive regulation of interleukin 2 biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 12 NA Homo sapiens

GOA TAX025101 GO:0045414 biological process regulation of interleukin 8 biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 12 NA Homo sapiens

GOA TAX033357 GO:1904251 biological process regulation of bile acid metabolic process Any process that modulates the frequency, rate or extent of bile acid metabolic process. (more detail) 12 NA Homo sapiens

GOA TAX034548 GO:2000232 biological process regulation of rRNA processing Any process that modulates the frequency, rate or extent of rRNA processing. (more detail) 12 NA Homo sapiens

GOA IEI002652 Protein protein interactors of human gene CLIP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLIP3 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI009844 Protein protein interactors of human gene PHF19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHF19 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI005242 Protein protein interactors of human gene GLCE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLCE (SwissProt ID=O (more detail) 12 17535438 Homo sapiens

I2D IEI007137 Protein protein interactors of human gene LAMTOR4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LAMTOR4 (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D TAX022163 GO:0033598 biological process mammary gland epithelial cell proliferation The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of (more detail) 12 NA Homo sapiens

GOA TAX030428 GO:0090239 biological process regulation of histone H4 acetylation Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modificatio (more detail) 12 NA Homo sapiens

GOA TAX021247 GO:0031953 biological process negative regulation of protein autophosphorylation Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or (more detail) 12 NA Homo sapiens

GOA TAX033697 GO:1904925 biological process positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondr (more detail) 12 NA Homo sapiens

GOA TAX028212 GO:0060965 biological process negative regulation of gene silencing by miRNA Any process that decreases the rate, frequency, or extent of the downregulation of gene expression t (more detail) 12 NA Homo sapiens

GOA IEI015203 Protein protein interactors of human gene ZBTB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI006561 Protein protein interactors of human gene ITPK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ITPK1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI005588 Protein protein interactors of human gene GTF2IRD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2IRD1 (SwissProt (more detail) 12 17535438 Homo sapiens

I2D TAX030008 GO:0072425 biological process signal transduction involved in G2 DNA damage checkpoint A signal transduction process that contributes to a G2/M transition DNA damage checkpoint. (more detail) 12 NA Homo sapiens

GOA TAX029819 GO:0072079 biological process nephron tubule formation The developmental process pertaining to the initial formation of a nephron tubule from unspecified p (more detail) 12 NA Homo sapiens

GOA TAX029541 GO:0071564 cellular component npBAF complex A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin (more detail) 12 NA Homo sapiens

GOA TAX018202 GO:0010896 biological process regulation of triglyceride catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways res (more detail) 12 NA Homo sapiens

GOA TAX025289 GO:0045820 biological process negative regulation of glycolytic process Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis. (more detail) 12 NA Homo sapiens

GOA TAX020602 GO:0030656 biological process regulation of vitamin metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 12 NA Homo sapiens

GOA TAX033437 GO:1904406 biological process negative regulation of nitric oxide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic (more detail) 12 NA Homo sapiens

GOA TAX032736 GO:1902993 biological process positive regulation of amyloid precursor protein catabolic process Any process that activates or increases the frequency, rate or extent of amyloid precursor protein c (more detail) 12 NA Homo sapiens

GOA TAX028832 GO:0070262 biological process peptidyl serine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine. (more detail) 12 NA Homo sapiens

GOA IEI006896 Protein protein interactors of human gene KLF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF2 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D TAX022674 GO:0034969 biological process histone arginine methylation The modification of a histone by addition of a methyl group to an arginine residue. (more detail) 12 NA Homo sapiens

GOA TAX024933 GO:0045078 biological process positive regulation of interferon gamma biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 12 NA Homo sapiens

GOA TAX026082 GO:0048185 molecular function activin binding Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits. (more detail) 12 NA Homo sapiens

GOA TAX033635 GO:1904816 biological process positive regulation of protein localization to chromosome, telomeric region Any process that activates or increases the frequency, rate or extent of protein localization to chr (more detail) 12 NA Homo sapiens

GOA TAX035031 GO:2001053 biological process regulation of mesenchymal cell apoptotic process Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process. (more detail) 12 NA Homo sapiens

GOA TAX021073 GO:0031597 cellular component cytosolic proteasome complex A proteasome complex found in the cytosol of a cell. (more detail) 12 NA Homo sapiens

GOA TAX021981 GO:0033127 biological process regulation of histone phosphorylation Any process that modulates the frequency, rate or extent of the addition of one or more phosphate gr (more detail) 12 NA Homo sapiens

GOA TAX018169 GO:0010857 molecular function calcium dependent protein kinase activity Catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the pres (more detail) 12 NA Homo sapiens

GOA TAX018175 GO:0010867 biological process positive regulation of triglyceride biosynthetic process Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride (more detail) 12 NA Homo sapiens

GOA TAX028126 GO:0060766 biological process negative regulation of androgen receptor signaling pathway Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway (more detail) 12 NA Homo sapiens

GOA IEI002679 Protein protein interactors of human gene CLTB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLTB (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI002829 Protein protein interactors of human gene COMMD10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD10 (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI009753 Protein protein interactors of human gene PER3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PER3 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI007187 Protein protein interactors of human gene LCOR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LCOR (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D TAX022388 GO:0034244 biological process negative regulation of transcription elongation from RNA polymerase II promoter Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongati (more detail) 12 NA Homo sapiens

GOA TAX020718 GO:0030914 cellular component STAGA complex A large multiprotein complex that possesses histone acetyltransferase and is involved in regulation (more detail) 12 NA Homo sapiens

GOA TAX032687 GO:1902902 biological process negative regulation of autophagosome assembly Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly. (more detail) 12 NA Homo sapiens

GOA TAX028797 GO:0070202 biological process regulation of establishment of protein localization to chromosome Any process that modulates the frequency, rate or extent of the directed movement of a protein to a (more detail) 12 NA Homo sapiens

GOA IEI015099 Protein protein interactors of human gene XAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XAF1 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D TAX020897 GO:0031282 biological process regulation of guanylate cyclase activity Any process that modulates the frequency, rate or extent of guanylate cyclase activity. (more detail) 12 NA Homo sapiens

GOA TAX000385 Genes annotated by the GO term GO:0042036. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. (more detail) 12 NA Homo sapiens

MSigDB TAX001391 Genes annotated by the GO term GO:0016566. Any activity that stops or downregulates transcription of specific genes or sets of genes. (more detail) 12 NA Homo sapiens

MSigDB TAX000282 Genes annotated by the GO term GO:0042095. The chemical reactions and pathways resulting in the formation of interferon gamma. (more detail) 12 NA Homo sapiens

MSigDB TAX000509 Genes annotated by the GO term GO:0050731. Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl tyrosine. (more detail) 12 NA Homo sapiens

MSigDB MOX003937 Genes associated with Computational Drug Signature beta Heparin Genes associated with Computational Drug Signature beta-Heparin, curated by the Drug Signature Datab (more detail) 12 25990557 Homo sapiens

DSigDB TAX014413 GO:0002739 biological process regulation of cytokine secretion involved in immune response Any process that modulates the frequency, rate, or extent of cytokine secretion contributing to an i (more detail) 12 NA Homo sapiens

GOA MAX002909 Examples of transcription factors whose activities are regulated by MAPK1 and MAPK3 [GeneID=5594;5595] phosphorylation. The mitogen-activated protein kinases (MAPKs) are a family of serine/threonine kinases that play an (more detail) 12 NA Homo sapiens

MSigDB WIG001032 Genes involved in Notch HLH transcription pathway (more detail) 12 NA Homo sapiens

MSigDB WIG001448 Chromatin Remodeling Chromatin Remodeling (more detail) 12 NA Homo sapiens

Protein Lounge MEX001634 Genes associated with Kinase Inhibitor Tandutinib Genes associated with Kinase Inhibitor Tandutinib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MOX001645 Genes associated with Computational Drug Signature 2,3,4,7,8 PENTACHLORODIBENZOFURAN Genes associated with Computational Drug Signature 2,3,4,7,8-PENTACHLORODIBENZOFURAN, curated by the (more detail) 12 25990557 Homo sapiens

DSigDB MOX001104 Genes associated with Computational Drug Signature BAPTA Genes associated with Computational Drug Signature BAPTA, curated by the Drug Signature Database (DS (more detail) 12 25990557 Homo sapiens

DSigDB FEX001571 Leukemia Andreeff08 13genes Supplementary Table 8 Differentially expressed genes in AML with 11q23 rearrangements vs. other UNFA (more detail) 12 18668134 Homo sapiens

GeneSigDB GEX000145 arthritis, rheumatoid|rheumatoid arthritis|anti tnf response arthritis, rheumatoid|rheumatoid arthritis|anti-tnf response associated genes. PAGER constructed thi (more detail) 12 NA Homo sapiens

GAD TAX017969 GO:0010561 biological process negative regulation of glycoprotein biosynthetic process Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways res (more detail) 12 NA Homo sapiens

GOA TAX018096 GO:0010755 biological process regulation of plasminogen activation Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen acti (more detail) 12 NA Homo sapiens

GOA MOX014858 Genes associated with Computational Drug Signature Ro 4396686 Genes associated with Computational Drug Signature Ro-4396686, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB FEX001570 Leukemia Andreeff08 12genes Supplementary Table 7 Genes associated with response to treatment. (more detail) 12 18668134 Homo sapiens

GeneSigDB TAX001240 Genes annotated by the GO term GO:0004707. Catalysis of the phosphorylation of proteins. Mitogen activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation or differentiation inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli. (more detail) 12 NA Homo sapiens

MSigDB TAX000639 Genes annotated by the GO term GO:0046328. Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade. (more detail) 12 NA Homo sapiens

MSigDB MOX003330 Genes associated with Computational Drug Signature AR A014418 Genes associated with Computational Drug Signature AR-A014418, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB MOX000946 Genes associated with Computational Drug Signature Modrasone Genes associated with Computational Drug Signature Modrasone, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB WAG000524 TRAF6 Mediated Induction of the antiviral cytokine IFN alpha/beta cascade (more detail) 12 NA Homo sapiens

Reactome WAG001263 Hypoxic and oxygen homeostasis regulation of HIF 1 alpha (more detail) 12 NA Homo sapiens

NCI-Nature Curated WIG001567 Inhibition of Ribosome Biogenesis by p14(ARF) Inhibition of Ribosome Biogenesis by p14(ARF) (more detail) 12 NA Homo sapiens

Protein Lounge TAX001381 Genes annotated by the GO term GO:0046332. Interacting selectively with a SMAD signaling protein. (more detail) 12 NA Homo sapiens

MSigDB TAX000035 Genes annotated by the GO term GO:0030521. Any series of molecular signals generated as a consequence of an androgen binding to its receptor. (more detail) 12 NA Homo sapiens

MSigDB TAX000400 Genes annotated by the GO term GO:0045936. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. (more detail) 12 NA Homo sapiens

MSigDB TAX000287 Genes annotated by the GO term GO:0032637. The appearance of interleukin 8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. (more detail) 12 NA Homo sapiens

MSigDB FEX001162 Immune Kong10 12genes ImmPort TGF betaFamilyMemberReceptors ImmPort genelist of cytokine receptors: TGF-beta Family Member Receptors (more detail) 12 20460173 Homo sapiens

GeneSigDB TAX001220 Genes annotated by the GO term GO:0019209. Increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. (more detail) 12 NA Homo sapiens

MSigDB TAX000807 Genes annotated by the GO term GO:0007260. The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. (more detail) 12 NA Homo sapiens

MSigDB MEX001423 Genes associated with Kinase Inhibitor Kinome 249 Genes associated with Kinase Inhibitor Kinome_249, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MOX000109 Genes associated with Computational Drug Signature Thymoquinone Genes associated with Computational Drug Signature Thymoquinone, curated by the Drug Signature Datab (more detail) 12 25990557 Homo sapiens

DSigDB TAX018392 GO:0014842 biological process regulation of skeletal muscle satellite cell proliferation Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell prolifera (more detail) 12 NA Homo sapiens

GOA TAX013783 GO:0001706 biological process endoderm formation The formation of the endoderm during gastrulation. (more detail) 12 NA Homo sapiens

GOA TAX014632 GO:0003198 biological process epithelial to mesenchymal transition involved in endocardial cushion formation A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular (more detail) 12 NA Homo sapiens

GOA TAX015445 GO:0004861 molecular function cyclin dependent protein serine/threonine kinase inhibitor activity Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase. (more detail) 12 NA Homo sapiens

GOA WAG001254 control of skeletal myogenesis by hdac and calcium/calmodulin dependent kinase (camk) The differentiation of muscle cells is transcriptiolly regulated, in part by the myocyte enhancer fa (more detail) 12 NA Homo sapiens

BioCarta WAG001481 Circadian rhythm pathway (more detail) 12 NA Homo sapiens

NCI-Nature Curated WIG000456 Control of Gene Expression by Vitamin D Receptor The vitamin D receptor, VDR is the mediator of all genomic actions of vitamin D3 and its analogs. It (more detail) 12 NA Homo sapiens

MSigDB TAX000544 Genes annotated by the GO term GO:0043241. The disaggregation of a protein complex into its constituent components. Protein complexes may have other associated non protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups. (more detail) 12 NA Homo sapiens

MSigDB TAX000401 Genes annotated by the GO term GO:0042326. Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. (more detail) 12 NA Homo sapiens

MSigDB TAX000641 Genes annotated by the GO term GO:0019216. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. (more detail) 12 NA Homo sapiens

MSigDB MOX005141 Genes associated with Computational Drug Signature gamma Tocopherol Genes associated with Computational Drug Signature gamma-Tocopherol, curated by the Drug Signature D (more detail) 12 25990557 Homo sapiens

DSigDB IEI001236 Protein protein interactors of human gene BATF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BATF2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX022914 GO:0035518 biological process histone H2A monoubiquitination The modification of histone H2A by addition of a single ubiquitin group. (more detail) 17 NA Homo sapiens

GOA TAX027820 GO:0060324 biological process face development The biological process whose specific outcome is the progression of a face from an initial condition (more detail) 17 NA Homo sapiens

GOA TAX030562 GO:0090545 cellular component CHD type complex A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) famil (more detail) 17 NA Homo sapiens

GOA TAX030404 GO:0090201 biological process negative regulation of release of cytochrome c from mitochondria Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondri (more detail) 17 NA Homo sapiens

GOA TAX034959 GO:2000831 biological process regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of steroid hormone secretion. (more detail) 17 NA Homo sapiens

GOA IEI006537 Protein protein interactors of human gene ITGAX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ITGAX (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI001318 Protein protein interactors of human gene BEX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BEX1 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D TAX034943 GO:2000811 biological process negative regulation of anoikis Any process that stops, prevents or reduces the frequency, rate or extent of anoikis. (more detail) 17 NA Homo sapiens

GOA TAX034526 GO:2000193 biological process positive regulation of fatty acid transport Any process that activates or increases the frequency, rate or extent of fatty acid transport. (more detail) 17 NA Homo sapiens

GOA TAX023661 GO:0042093 biological process T helper cell differentiation The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helpe (more detail) 17 NA Homo sapiens

GOA IEI006294 Protein protein interactors of human gene IL12B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL12B (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI009450 Protein protein interactors of human gene PAGR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAGR1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI009924 Protein protein interactors of human gene PIK3C2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIK3C2B (SwissProt I (more detail) 17 17535438 Homo sapiens

I2D TAX019107 GO:0016581 cellular component NuRD complex An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activi (more detail) 17 NA Homo sapiens

GOA TAX025494 GO:0046209 biological process nitric oxide metabolic process The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas (more detail) 17 NA Homo sapiens

GOA TAX020665 GO:0030851 biological process granulocyte differentiation The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Gr (more detail) 17 NA Homo sapiens

GOA TAX023336 GO:0036315 biological process cellular response to sterol Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 17 NA Homo sapiens

GOA IEI004329 Protein protein interactors of human gene ETV4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ETV4 (SwissProt ID=P (more detail) 17 17535438 Homo sapiens

I2D IEI012064 Protein protein interactors of human gene SETD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SETD2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX032351 GO:1902043 biological process positive regulation of extrinsic apoptotic signaling pathway via death domain receptors Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signali (more detail) 17 NA Homo sapiens

GOA FEX000679 Breast Habermann09 18genes Supplemental Table 2: Expression levels of genes that are potentially involved in the maintenance of (more detail) 17 19101988 Homo sapiens

GeneSigDB TAX014162 GO:0002294 biological process CD4 positive, alpha beta T cell differentiation involved in immune response The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized (more detail) 17 NA Homo sapiens

GOA MEX001852 Genes associated with Kinase Inhibitor PD166285 Genes associated with Kinase Inhibitor PD166285, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB WAG000661 p38 MAPK signaling pathway (more detail) 17 NA Homo sapiens

NCI-Nature Curated WAG001450 phosphoinositides and their downstream targets Nine currently identified phosphoinositide 3-kises (PI 3-K) constitute a subfamily of lipid kises th (more detail) 17 NA Homo sapiens

BioCarta MOX018086 Genes associated with Computational Drug Signature Vandetanib Genes associated with Computational Drug Signature Vandetanib, curated by the Drug Signature Databas (more detail) 17 25990557 Homo sapiens

DSigDB WIG000026 Degradation of beta catenin (more detail) 17 NA Homo sapiens

MSigDB WIG001644 RANK Pathway RANK Pathway (more detail) 17 NA Homo sapiens

Protein Lounge WIG000206 The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. na (more detail) 17 NA Homo sapiens

MSigDB MAX001131 Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive ALL (B and T lineage ALL); here genes down regulated in the drug resistant samples. Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percen (more detail) 17 NA Homo sapiens

MSigDB MOX004959 Genes associated with Computational Drug Signature bupropion Genes associated with Computational Drug Signature bupropion, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens

DSigDB MEX001699 Genes associated with Kinase Inhibitor GW806742X Genes associated with Kinase Inhibitor GW806742X, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB WIG000359 IL 7 Signal Transduction IL-7 is a key cytokine in the immune system, essential for normal development of B cells and T cells (more detail) 17 NA Homo sapiens

MSigDB FEX001589 Leukemia Sanchez Guijo08 19genes SuppTable2o Genes involved in protein phosphorilation (more detail) 17 18722011 Homo sapiens

GeneSigDB MEX001654 Genes associated with Kinase Inhibitor CHEMBL2062936 Genes associated with Kinase Inhibitor CHEMBL2062936, curated by the Drug Signature Database (DSigDB (more detail) 17 25990557 Homo sapiens

DSigDB TAX014732 GO:0003401 biological process axis elongation The developmental growth that results in the elongation of a line that defines polarity or symmetry (more detail) 17 NA Homo sapiens

GOA WIG000008 Cellular roles of Anthrax toxin (more detail) 17 NA Homo sapiens

MSigDB FEX000082 Bone Heller08 28genes Table 1. Selected proto-oncogenes down-regulated by Aza-dC TSA and Aza-dC/TSA in MM cell lines (more detail) 17 18172295 Homo sapiens

GeneSigDB WAG000217 nerve growth factor pathway (ngf) Nerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and prolifera (more detail) 17 NA Homo sapiens

BioCarta IEI002245 Protein protein interactors of human gene CDK16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK16 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D TAX021805 GO:0032814 biological process regulation of natural killer cell activation Any process that modulates the frequency, rate or extent of natural killer cell activation. (more detail) 27 NA Homo sapiens

GOA IEI008621 Protein protein interactors of human gene NCF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCF2 (SwissProt ID=P (more detail) 27 17535438 Homo sapiens

I2D IEI009971 Protein protein interactors of human gene PITX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PITX1 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D TAX024586 GO:0044068 biological process modulation by symbiont of host cellular process Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular proce (more detail) 27 NA Homo sapiens

GOA IEI007796 Protein protein interactors of human gene MCM3AP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCM3AP (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D IEI011530 Protein protein interactors of human gene RPL34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL34 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D TAX024118 GO:0043029 biological process T cell homeostasis The process of regulating the proliferation and elimination of T cells such that the total number of (more detail) 27 NA Homo sapiens

GOA TAX033256 GO:1904019 biological process epithelial cell apoptotic process Any apoptotic process in an epithelial cell. (more detail) 27 NA Homo sapiens

GOA IEI004659 Protein protein interactors of human gene FBXO7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO7 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI005739 Protein protein interactors of human gene HCLS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HCLS1 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI008629 Protein protein interactors of human gene NCKIPSD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCKIPSD (SwissProt I (more detail) 27 17535438 Homo sapiens

I2D IEI006371 Protein protein interactors of human gene ILVBL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ILVBL (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D MOX003289 Genes associated with Computational Drug Signature Perfluorohexanesulfonic acid Genes associated with Computational Drug Signature Perfluorohexanesulfonic acid, curated by the Drug (more detail) 27 25990557 Homo sapiens

DSigDB TAX014402 GO:0002724 biological process regulation of T cell cytokine production Any process that modulates the frequency, rate, or extent of T cell cytokine production. (more detail) 27 NA Homo sapiens

GOA MOX000346 Genes associated with Computational Drug Signature formononetin Genes associated with Computational Drug Signature formononetin, curated by the Drug Signature Datab (more detail) 27 25990557 Homo sapiens

DSigDB FEX002920 StemCell Enk06 334genes Table 2. p53 target gene expression changes in intact human epidermis following in vivo UVB irradiat (more detail) 27 16434974 Homo sapiens

GeneSigDB GEX167067 Type 2 diabetes Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. (more detail) 27 20581827 Homo sapiens

GWAS Catalog MOX004762 Genes associated with Computational Drug Signature DL Thyroxine Genes associated with Computational Drug Signature DL-Thyroxine, curated by the Drug Signature Datab (more detail) 27 25990557 Homo sapiens

DSigDB MOX001735 Genes associated with Computational Drug Signature NITAZOXANIDE Genes associated with Computational Drug Signature NITAZOXANIDE, curated by the Drug Signature Datab (more detail) 27 25990557 Homo sapiens

DSigDB MOX004689 Genes associated with Computational Drug Signature STREPTOZOTOCIN Genes associated with Computational Drug Signature STREPTOZOTOCIN, curated by the Drug Signature Dat (more detail) 27 25990557 Homo sapiens

DSigDB TAX014456 GO:0002827 biological process positive regulation of T helper 1 type immune response Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune r (more detail) 19 NA Homo sapiens

GOA WAG000047 VEGFR3 signaling in lymphatic endothelium (more detail) 19 NA Homo sapiens

NCI-Nature Curated TAX017159 GO:0008266 molecular function poly(U) RNA binding Interacting selectively and non-covalently with a sequence of uracil residues in an RNA molecule. (more detail) 19 NA Homo sapiens

GOA WIG000315 EPO Signaling Pathway Erythropoietin functions to increase the number of red blood cells. Thus, it has found utility as a (more detail) 19 NA Homo sapiens

MSigDB MEX001303 Genes associated with Kinase Inhibitor Kinome 1198 Genes associated with Kinase Inhibitor Kinome_1198, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB MEX001650 Genes associated with Kinase Inhibitor GNE 7915 Genes associated with Kinase Inhibitor GNE-7915, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB WIG001965 Apoptosis Modulation by HSP70 Apoptosis Modulation by HSP70 (more detail) 19 NA Homo sapiens

WikiPathway TAX000810 Genes annotated by the GO term GO:0042098. The expansion of a T cell population by cell division. Follows T cell activation. (more detail) 19 NA Homo sapiens

MSigDB FEX002376 MesenchymalStemCells Nekanti09 24genes Table 2. Comparison of transcription profile of stem cell and early lineage differentiation genes of (more detail) 19 20877435 Homo sapiens

GeneSigDB MAX000012 Genes down regulated in immunoglobulin light chain amyloidosis plasma cells (ALPC) compared to multiple myeloma (MM) cells. Immunoglobulin light chain amyloidosis (AL) is characterized by a clonal expansion of plasma cells w (more detail) 19 NA Homo sapiens

MSigDB TAX018145 GO:0010829 biological process negative regulation of glucose transmembrane transport Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glu (more detail) 19 NA Homo sapiens

GOA FEX003437 Viral Chen07 24genes Supplemental Table 1: Core Unique Genes that were significantly and differentially expressed (more detail) 19 17404395 Homo sapiens

GeneSigDB WIG000451 Role of Tob in T cell activation Regulation of T cell activation is a crucial component of balanced functioning of the immune system. (more detail) 19 NA Homo sapiens

MSigDB MOX007285 Genes associated with Computational Drug Signature bifonazole Genes associated with Computational Drug Signature bifonazole, curated by the Drug Signature Databas (more detail) 19 25990557 Homo sapiens

DSigDB MEX001463 Genes associated with Kinase Inhibitor LDN193189 Genes associated with Kinase Inhibitor LDN193189, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB FEX000053 Bone Dring04 23genes Table 2 Nuclear Genes with significant mean differences between t(4;14) and non-t(4;14) cases arrang (more detail) 19 15355895 Homo sapiens

GeneSigDB FEX000886 Colon Grade06 19genes Table 1b. Expression and P values for additional genes from ingenuity pathway analysis networks in F (more detail) 19 16397240 Homo sapiens

GeneSigDB MOX003103 Genes associated with Computational Drug Signature RH 1 Genes associated with Computational Drug Signature RH 1, curated by the Drug Signature Database (DSi (more detail) 19 25990557 Homo sapiens

DSigDB MEX001386 Genes associated with Kinase Inhibitor Masitinib Genes associated with Kinase Inhibitor Masitinib, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB TAX018021 GO:0010640 biological process regulation of platelet derived growth factor receptor signaling pathway Any process that modulates the frequency, rate or extent of the platelet-derived growth factor recep (more detail) 19 NA Homo sapiens

GOA TAX029098 GO:0070741 biological process response to interleukin 6 Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 19 NA Homo sapiens

GOA IEI008883 Protein protein interactors of human gene NLRP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NLRP2 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI009349 Protein protein interactors of human gene OSBPL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OSBPL3 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D TAX023265 GO:0036119 biological process response to platelet derived growth factor Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 19 NA Homo sapiens

GOA TAX022749 GO:0035162 biological process embryonic hemopoiesis The stages of blood cell formation that take place within the embryo. (more detail) 19 NA Homo sapiens

GOA TAX026450 GO:0050431 molecular function transforming growth factor beta binding Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifu (more detail) 19 NA Homo sapiens

GOA TAX029643 GO:0071731 biological process response to nitric oxide Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 19 NA Homo sapiens

GOA TAX035004 GO:2001014 biological process regulation of skeletal muscle cell differentiation Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. (more detail) 19 NA Homo sapiens

GOA IEI000421 Protein protein interactors of human gene AKAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKAP1 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI009540 Protein protein interactors of human gene PBDC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PBDC1 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX034517 GO:2000178 biological process negative regulation of neural precursor cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell (more detail) 19 NA Homo sapiens

GOA IEI011606 Protein protein interactors of human gene RPS6KA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS6KA4 (SwissProt I (more detail) 19 17535438 Homo sapiens

I2D IEI015366 Protein protein interactors of human gene ZMYM3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZMYM3 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX018854 GO:0016075 biological process rRNA catabolic process The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural (more detail) 19 NA Homo sapiens

GOA IEI015211 Protein protein interactors of human gene ZBTB32 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB32 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D TAX032398 GO:1902170 biological process cellular response to reactive nitrogen species Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 19 NA Homo sapiens

GOA TAX018289 GO:0014002 biological process astrocyte development The process aimed at the progression of an astrocyte over time, from initial commitment of the cell (more detail) 19 NA Homo sapiens

GOA TAX017095 GO:0008157 molecular function protein phosphatase 1 binding Interacting selectively and non-covalently with the enzyme protein phosphatase 1. (more detail) 19 NA Homo sapiens

GOA TAX021123 GO:0031690 molecular function adrenergic receptor binding Interacting selectively and non-covalently with an adrenergic receptor. (more detail) 19 NA Homo sapiens

GOA IEI013044 Protein protein interactors of human gene ST14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ST14 (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D IEI005193 Protein protein interactors of human gene GID8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GID8 (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D IEI005084 Protein protein interactors of human gene GATAD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GATAD1 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D TAX027574 GO:0055093 biological process response to hyperoxia Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 19 NA Homo sapiens

GOA TAX027012 GO:0051446 biological process positive regulation of meiotic cell cycle Any process that activates or increases the frequency, rate or extent of progression through the mei (more detail) 19 NA Homo sapiens

GOA TAX034895 GO:2000738 biological process positive regulation of stem cell differentiation Any process that activates or increases the frequency, rate or extent of stem cell differentiation. (more detail) 19 NA Homo sapiens

GOA TAX022308 GO:0034104 biological process negative regulation of tissue remodeling Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling. (more detail) 19 NA Homo sapiens

GOA IEI005061 Protein protein interactors of human gene GAPVD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GAPVD1 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI010192 Protein protein interactors of human gene POLD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLD2 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D TAX026662 GO:0050886 biological process endocrine process The process that involves the secretion of or response to endocrine hormones. An endocrine hormone i (more detail) 25 NA Homo sapiens

GOA IEI013324 Protein protein interactors of human gene TACC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TACC1 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI010740 Protein protein interactors of human gene PTPN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTPN3 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI002276 Protein protein interactors of human gene CDKN2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDKN2B (SwissProt ID (more detail) 25 17535438 Homo sapiens

I2D IEI001685 Protein protein interactors of human gene CABIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CABIN1 (SwissProt ID (more detail) 25 17535438 Homo sapiens

I2D TAX025389 GO:0045992 biological process negative regulation of embryonic development Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. (more detail) 25 NA Homo sapiens

GOA IEI005655 Protein protein interactors of human gene H2AC7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AC7 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI004557 Protein protein interactors of human gene FAM98A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM98A (SwissProt ID (more detail) 25 17535438 Homo sapiens

I2D IEI015143 Protein protein interactors of human gene YARS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YARS1 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D TAX000486 Genes annotated by the GO term GO:0045597. Any process that activates or increases the frequency, rate or extent of cell differentiation. (more detail) 25 NA Homo sapiens

MSigDB MOX000212 Genes associated with Computational Drug Signature edaravone Genes associated with Computational Drug Signature edaravone, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB TAX013986 GO:0001990 biological process regulation of systemic arterial blood pressure by hormone The process in which hormones modulate the force with which blood passes through the circulatory sys (more detail) 25 NA Homo sapiens

GOA TAX000446 Genes annotated by the GO term GO:0006730. The chemical reactions and pathways involving compounds containing a single carbon atom. (more detail) 25 NA Homo sapiens

MSigDB MOX014571 Genes associated with Computational Drug Signature podophyllotoxin Genes associated with Computational Drug Signature podophyllotoxin, curated by the Drug Signature Da (more detail) 25 25990557 Homo sapiens

DSigDB MOX012582 Genes associated with Computational Drug Signature ETHACRYNIC ACID Genes associated with Computational Drug Signature ETHACRYNIC ACID, curated by the Drug Signature Da (more detail) 25 25990557 Homo sapiens

DSigDB MOX002449 Genes associated with Computational Drug Signature carnosol Genes associated with Computational Drug Signature carnosol, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB MEX002062 Genes associated with Kinase Inhibitor Crenolanib Genes associated with Kinase Inhibitor Crenolanib, curated by the Drug Signature Database (DSigDB). (more detail) 25 25990557 Homo sapiens

DSigDB WIG001292 Genes involved in Transferrin endocytosis and recycling (more detail) 25 NA Homo sapiens

MSigDB FEX001788 Lung Wikman02 26genes Table 1 Genes found deregulated in both the PCA analysis and the permutation test (more detail) 25 12173052 Homo sapiens

GeneSigDB MOX018088 Genes associated with Computational Drug Signature Vemurafenib Genes associated with Computational Drug Signature Vemurafenib, curated by the Drug Signature Databa (more detail) 25 25990557 Homo sapiens

DSigDB FEX003369 Viral Sun01 27genes Apoptosis Related TABLE 2. Expression Profile of Apoptosis-Related Genes in BC-2 Cells and Its Effect by MAP30 (more detail) 25 11573962 Homo sapiens

GeneSigDB MOX012296 Genes associated with Computational Drug Signature Digitoxigenin Genes associated with Computational Drug Signature Digitoxigenin, curated by the Drug Signature Data (more detail) 25 25990557 Homo sapiens

DSigDB MOX004137 Genes associated with Computational Drug Signature Crystal violet Genes associated with Computational Drug Signature Crystal violet, curated by the Drug Signature Dat (more detail) 25 25990557 Homo sapiens

DSigDB MOX003193 Genes associated with Computational Drug Signature Lu 19005 Genes associated with Computational Drug Signature Lu 19005, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB WAG000632 regulation of ck1/cdk5 by type 1 glutamate receptors Cdk5 is a cyclin dependent protein kise involved in dopaminergic sigling in the neostriatal region o (more detail) 21 NA Homo sapiens

BioCarta MOX017139 Genes associated with Computational Drug Signature Axitinib Genes associated with Computational Drug Signature Axitinib, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens

DSigDB TAX014027 GO:0002052 biological process positive regulation of neuroblast proliferation Any process that activates or increases the rate of neuroblast proliferation. (more detail) 21 NA Homo sapiens

GOA MOX007316 Genes associated with Computational Drug Signature bisindolylmaleimide IX Genes associated with Computational Drug Signature bisindolylmaleimide IX, curated by the Drug Signa (more detail) 21 25990557 Homo sapiens

DSigDB MEX000391 Genes associated with Approved Drug apomorphine Genes associated with Approved Drug apomorphine, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens

DSigDB MEX001652 Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens

DSigDB TAX014685 GO:0003300 biological process cardiac muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardi (more detail) 21 NA Homo sapiens

GOA MOX003294 Genes associated with Computational Drug Signature purvalanol A Genes associated with Computational Drug Signature purvalanol A, curated by the Drug Signature Datab (more detail) 21 25990557 Homo sapiens

DSigDB FEX002809 StemCell Shim04 25genes DownRegulated Table 6. Top 25 most highly down-regulated genes (more detail) 21 15246160 Homo sapiens

GeneSigDB MOX013466 Genes associated with Computational Drug Signature liothyronine Genes associated with Computational Drug Signature liothyronine, curated by the Drug Signature Datab (more detail) 21 25990557 Homo sapiens

DSigDB MOX000612 Genes associated with Computational Drug Signature formoterol Genes associated with Computational Drug Signature formoterol, curated by the Drug Signature Databas (more detail) 21 25990557 Homo sapiens

DSigDB MOX015655 Genes associated with Computational Drug Signature TRYPAN BLUE Genes associated with Computational Drug Signature TRYPAN BLUE, curated by the Drug Signature Databa (more detail) 21 25990557 Homo sapiens

DSigDB TAX021724 GO:0032703 biological process negative regulation of interleukin 2 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 product (more detail) 21 NA Homo sapiens

GOA TAX030300 GO:0090050 biological process positive regulation of cell migration involved in sprouting angiogenesis Any process that increases the frequency, rate or extent of cell migration involved in sprouting ang (more detail) 21 NA Homo sapiens

GOA IEI000878 Protein protein interactors of human gene ARL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARL2 (SwissProt ID=P (more detail) 21 17535438 Homo sapiens

I2D IEI007723 Protein protein interactors of human gene MARK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MARK1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI006403 Protein protein interactors of human gene INO80C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INO80C (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI014040 Protein protein interactors of human gene TNKS1BP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNKS1BP1 (SwissProt (more detail) 21 17535438 Homo sapiens

I2D TAX025211 GO:0045663 biological process positive regulation of myoblast differentiation Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A (more detail) 21 NA Homo sapiens

GOA TAX032293 GO:1901889 biological process negative regulation of cell junction assembly Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly. (more detail) 21 NA Homo sapiens

GOA TAX018182 GO:0010874 biological process regulation of cholesterol efflux Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux i (more detail) 21 NA Homo sapiens

GOA TAX021696 GO:0032656 biological process regulation of interleukin 13 production Any process that modulates the frequency, rate, or extent of interleukin-13 production. (more detail) 21 NA Homo sapiens

GOA IEI012037 Protein protein interactors of human gene SERPINB5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERPINB5 (SwissProt (more detail) 21 17535438 Homo sapiens

I2D IEI003997 Protein protein interactors of human gene EGLN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EGLN2 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI009839 Protein protein interactors of human gene PHF10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHF10 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D TAX025165 GO:0045606 biological process positive regulation of epidermal cell differentiation Any process that activates or increases the frequency, rate or extent of epidermal cell differentiat (more detail) 21 NA Homo sapiens

GOA TAX029779 GO:0072009 biological process nephron epithelium development The process whose specific outcome is the progression of the nephron epithelium over time, from its (more detail) 21 NA Homo sapiens

GOA IEI001651 Protein protein interactors of human gene C7orf50 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C7orf50 (SwissProt I (more detail) 21 17535438 Homo sapiens

I2D IEI011894 Protein protein interactors of human gene SCYL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCYL2 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI002540 Protein protein interactors of human gene CHTF18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHTF18 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI013474 Protein protein interactors of human gene TCEAL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCEAL1 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D TAX028266 GO:0061037 biological process negative regulation of cartilage development Any process that decreases the rate, frequency, or extent of cartilage development, the process whos (more detail) 23 NA Homo sapiens

GOA IEI007496 Protein protein interactors of human gene LTF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LTF (SwissProt ID=P0 (more detail) 23 17535438 Homo sapiens

I2D TAX024317 GO:0043367 biological process CD4 positive, alpha beta T cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4 (more detail) 23 NA Homo sapiens

GOA IEI011327 Protein protein interactors of human gene RIOK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RIOK2 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI002936 Protein protein interactors of human gene CPS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CPS1 (SwissProt ID=P (more detail) 23 17535438 Homo sapiens

I2D IEI001737 Protein protein interactors of human gene CALML5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CALML5 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D TAX019952 GO:0021545 biological process cranial nerve development The process whose specific outcome is the progression of the cranial nerves over time, from its form (more detail) 23 NA Homo sapiens

GOA IEI015421 Protein protein interactors of human gene ZNF212 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF212 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI001499 Protein protein interactors of human gene BZW2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BZW2 (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D IEI004348 Protein protein interactors of human gene EXO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXO1 (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D IEI002063 Protein protein interactors of human gene CCR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCR1 (SwissProt ID=P (more detail) 23 17535438 Homo sapiens

I2D IEI004251 Protein protein interactors of human gene ERCC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERCC4 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D MOX001350 Genes associated with Computational Drug Signature IN1541 Genes associated with Computational Drug Signature IN1541, curated by the Drug Signature Database (D (more detail) 23 25990557 Homo sapiens

DSigDB MOX007465 Genes associated with Computational Drug Signature camptothecin Genes associated with Computational Drug Signature camptothecin, curated by the Drug Signature Datab (more detail) 23 25990557 Homo sapiens

DSigDB TAX000648 Genes annotated by the GO term GO:0007346. Any process that modulates the rate or extent of progress through the mitotic cell cycle. (more detail) 23 NA Homo sapiens

MSigDB MAX003265 Genes in cluster 1: strongly up regulated in HFW cells (fibroblast) upon treatment with sodium arsenite [PubChem=26435] at all time points. Arsenic compounds are widely distributed and arsenic ingestion is associated with many human disease (more detail) 23 NA Homo sapiens

MSigDB TAX018261 GO:0010971 biological process positive regulation of G2/M transition of mitotic cell cycle Any process that increases the rate or extent of progression from G2 phase to M phase of the mitotic (more detail) 23 NA Homo sapiens

GOA FEX001704 Liver Chiba04 24genes Table 3. Genes downregulated (ratio (more detail) 23 15452378 Homo sapiens

GeneSigDB WIG000412 Phosphoinositides and their downstream targets. Nine currently identified phosphoinositide 3-kinases (PI 3-K) constitute a subfamily of lipid kinase (more detail) 23 NA Homo sapiens

MSigDB MEX001418 Genes associated with Kinase Inhibitor TSU 68 Genes associated with Kinase Inhibitor TSU-68, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens

DSigDB MOX015610 Genes associated with Computational Drug Signature triamterene Genes associated with Computational Drug Signature triamterene, curated by the Drug Signature Databa (more detail) 23 25990557 Homo sapiens

DSigDB WAG000831 fmlp induced chemokine gene expression in hmc 1 cells Neutrophils respond to bacterial infection by releasing reactive oxygen species that kill bacteria a (more detail) 23 NA Homo sapiens

BioCarta MOX017176 Genes associated with Computational Drug Signature triamterene Genes associated with Computational Drug Signature triamterene, curated by the Drug Signature Databa (more detail) 23 25990557 Homo sapiens

DSigDB TAX000526 Genes annotated by the GO term GO:0051050. Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells. (more detail) 23 NA Homo sapiens

MSigDB WIG000421 Ras Signaling Pathway Ras activates many signaling cascades. Here we illustrate some of the well-characterized cascades in (more detail) 23 NA Homo sapiens

MSigDB IEI003359 Protein protein interactors of human gene DCLRE1C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCLRE1C (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI008903 Protein protein interactors of human gene NMNAT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NMNAT1 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI005680 Protein protein interactors of human gene H3 5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H3-5 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI007620 Protein protein interactors of human gene MAML3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAML3 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX028736 GO:0070102 biological process interleukin 6 mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface (more detail) 14 NA Homo sapiens

GOA TAX021408 GO:0032239 biological process regulation of nucleobase containing compound transport Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nu (more detail) 14 NA Homo sapiens

GOA TAX029126 GO:0070828 biological process heterochromatin organization Any process that results in the specification, formation or maintenance of the physical structure of (more detail) 14 NA Homo sapiens

GOA IEI013003 Protein protein interactors of human gene SRSF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF8 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI000294 Protein protein interactors of human gene ADH5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADH5 (SwissProt ID=P (more detail) 14 17535438 Homo sapiens

I2D IEI014037 Protein protein interactors of human gene TNK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNK1 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D TAX023998 GO:0042754 biological process negative regulation of circadian rhythm Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm beh (more detail) 14 NA Homo sapiens

GOA IEI004868 Protein protein interactors of human gene FOXH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXH1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX017878 GO:0010225 biological process response to UV C Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 14 NA Homo sapiens

GOA TAX026149 GO:0048333 biological process mesodermal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm (more detail) 14 NA Homo sapiens

GOA TAX022382 GO:0034236 molecular function protein kinase A catalytic subunit binding Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kin (more detail) 14 NA Homo sapiens

GOA IEI000133 Protein protein interactors of human gene ACKR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACKR2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI001224 Protein protein interactors of human gene BAMBI from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BAMBI (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX022760 GO:0035196 biological process production of miRNAs involved in gene silencing by miRNA Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily s (more detail) 14 NA Homo sapiens

GOA TAX026311 GO:0048711 biological process positive regulation of astrocyte differentiation Any process that activates or increases the frequency, rate or extent of astrocyte differentiation. (more detail) 14 NA Homo sapiens

GOA IEI004120 Protein protein interactors of human gene ELSPBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELSPBP1 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI005284 Protein protein interactors of human gene GMFB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GMFB (SwissProt ID=P (more detail) 14 17535438 Homo sapiens

I2D IEI007194 Protein protein interactors of human gene LDB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LDB2 (SwissProt ID=O (more detail) 14 17535438 Homo sapiens

I2D IEI000809 Protein protein interactors of human gene ARHGAP21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARHGAP21 (SwissProt (more detail) 14 17535438 Homo sapiens

I2D TAX031164 GO:0098847 molecular function sequence specific single stranded DNA binding Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composi (more detail) 14 NA Homo sapiens

GOA IEI008654 Protein protein interactors of human gene NDFIP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NDFIP2 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D WAG000639 map kinase inactivation of smrt corepressor Corepressors are coregulators that interact with transcriptiol silencers in a variety of pathways su (more detail) 14 NA Homo sapiens

BioCarta MEX002082 Genes associated with Kinase Inhibitor GW795493X Genes associated with Kinase Inhibitor GW795493X, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB TAX001110 Genes annotated by the GO term GO:0043028. Modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. (more detail) 14 NA Homo sapiens

MSigDB WIG001058 Genes involved in p75NTR signals via NF kB (more detail) 14 NA Homo sapiens

MSigDB MEX001731 Genes associated with Kinase Inhibitor TCMDC 141371 Genes associated with Kinase Inhibitor TCMDC-141371, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens

DSigDB MEX003830 Genes associated with Perturbagen Signature PF 00562151 00 Genes associated with Perturbagen Signature PF-00562151-00, curated by the Drug Signature Database ( (more detail) 14 25990557 Homo sapiens

DSigDB MEX002415 Genes associated with Kinase Inhibitor Ceritinib Genes associated with Kinase Inhibitor Ceritinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX001177 Genes associated with Computational Drug Signature 5630 53 5 Genes associated with Computational Drug Signature 5630-53-5, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB WIG000436 Regulation of hematopoiesis by cytokines The process of hematopoesis is regulated by various cytokines. The combination of cytokines stimulat (more detail) 14 NA Homo sapiens

MSigDB MEX000147 Genes associated with Approved Drug gemfibrozil Genes associated with Approved Drug gemfibrozil, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX003543 Genes associated with Computational Drug Signature Vismodegib Genes associated with Computational Drug Signature Vismodegib, curated by the Drug Signature Databas (more detail) 14 25990557 Homo sapiens

DSigDB TAX000365 Genes annotated by the GO term GO:0002573. The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. (more detail) 14 NA Homo sapiens

MSigDB TAX014458 GO:0002829 biological process negative regulation of type 2 immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune respo (more detail) 14 NA Homo sapiens

GOA WAG001022 phosphorylation of mek1 by cdk5/p35 down regulates the map kinase pathway Map kises transduce responses to extracellular sigls by a variety of routes, and communicate with ot (more detail) 14 NA Homo sapiens

BioCarta TAX000687 Genes annotated by the GO term GO:0017015. Any process that modulates the frequency, rate or extent of activity of any TGFbeta receptor signaling pathway. (more detail) 14 NA Homo sapiens

MSigDB MEX002135 Genes associated with Kinase Inhibitor Bisindolylmaleimide XI, HCl Genes associated with Kinase Inhibitor Bisindolylmaleimide XI, HCl, curated by the Drug Signature Da (more detail) 14 25990557 Homo sapiens

DSigDB MOX004534 Genes associated with Computational Drug Signature Phylloquinone Genes associated with Computational Drug Signature Phylloquinone, curated by the Drug Signature Data (more detail) 14 25990557 Homo sapiens

DSigDB TAX018401 GO:0014857 biological process regulation of skeletal muscle cell proliferation Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. (more detail) 14 NA Homo sapiens

GOA WAG000642 cadmium induces dna synthesis and proliferation in macrophages Exposure to divalent cadmium ions (Cd2+) is a known cancer risk factor, but the molecular mechanisms (more detail) 14 NA Homo sapiens

BioCarta TAX000393 Genes annotated by the GO term GO:0002683. Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. (more detail) 14 NA Homo sapiens

MSigDB MAX000922 Genes encoding the NF kB core signaling proteins. This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-kap (more detail) 14 NA Homo sapiens

MSigDB WIG001238 Genes involved in Spry regulation of FGF signaling (more detail) 14 NA Homo sapiens

MSigDB WIG000178 JNK signaling in the CD4+ TCR pathway (more detail) 14 NA Homo sapiens

MSigDB MEX002123 Genes associated with Kinase Inhibitor Fostamatinib Genes associated with Kinase Inhibitor Fostamatinib, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens

DSigDB IEI013626 Protein protein interactors of human gene TGFA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TGFA (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D IEI005846 Protein protein interactors of human gene HINT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HINT1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI012014 Protein protein interactors of human gene SERF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERF2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI015823 Protein protein interactors of human gene ZNHIT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNHIT3 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI009505 Protein protein interactors of human gene PARP12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PARP12 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX023177 GO:0035970 biological process peptidyl threonine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine. (more detail) 16 NA Homo sapiens

GOA IEI003834 Protein protein interactors of human gene DUSP10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP10 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI001539 Protein protein interactors of human gene C18orf25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C18orf25 (SwissProt (more detail) 16 17535438 Homo sapiens

I2D TAX031572 GO:0106058 biological process positive regulation of calcineurin mediated signaling Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signal (more detail) 16 NA Homo sapiens

GOA IEI014284 Protein protein interactors of human gene TRIP11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIP11 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX020696 GO:0030889 biological process negative regulation of B cell proliferation Any process that stops, prevents or reduces the rate or extent of B cell proliferation. (more detail) 16 NA Homo sapiens

GOA TAX023483 GO:0038084 biological process vascular endothelial growth factor signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF (more detail) 16 NA Homo sapiens

GOA TAX017383 GO:0008631 biological process intrinsic apoptotic signaling pathway in response to oxidative stress A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic (more detail) 16 NA Homo sapiens

GOA TAX027994 GO:0060561 biological process apoptotic process involved in morphogenesis Any apoptotic process that contributes to the shaping of an anatomical structure. (more detail) 16 NA Homo sapiens

GOA TAX029443 GO:0071404 biological process cellular response to low density lipoprotein particle stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 16 NA Homo sapiens

GOA IEI013475 Protein protein interactors of human gene TCEAL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCEAL2 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX026327 GO:0048745 biological process smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle over time, from its formation (more detail) 16 NA Homo sapiens

GOA IEI004388 Protein protein interactors of human gene F13A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene F13A1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI011178 Protein protein interactors of human gene REPIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene REPIN1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX024960 GO:0045120 cellular component pronucleus The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized (more detail) 16 NA Homo sapiens

GOA TAX024548 GO:0043968 biological process histone H2A acetylation The modification of histone H2A by the addition of an acetyl group. (more detail) 16 NA Homo sapiens

GOA TAX031965 GO:1900746 biological process regulation of vascular endothelial growth factor signaling pathway Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signa (more detail) 16 NA Homo sapiens

GOA IEI008960 Protein protein interactors of human gene NOTCH4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOTCH4 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI002204 Protein protein interactors of human gene CDCA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDCA4 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI011156 Protein protein interactors of human gene RECQL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RECQL4 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI008232 Protein protein interactors of human gene MRPS15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPS15 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX029165 GO:0070886 biological process positive regulation of calcineurin NFAT signaling cascade Any process that activates or increases the frequency, rate or extent of signaling via the calcineur (more detail) 16 NA Homo sapiens

GOA TAX018086 GO:0010744 biological process positive regulation of macrophage derived foam cell differentiation Any process that increases the rate, frequency or extent of macrophage derived foam cell differentia (more detail) 16 NA Homo sapiens

GOA IEI011281 Protein protein interactors of human gene RHOBTB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RHOBTB1 (SwissProt I (more detail) 16 17535438 Homo sapiens

I2D TAX021720 GO:0032695 biological process negative regulation of interleukin 12 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 produc (more detail) 16 NA Homo sapiens

GOA TAX021450 GO:0032305 biological process positive regulation of icosanoid secretion Any process that activates or increases the frequency, rate or extent of the controlled release of a (more detail) 16 NA Homo sapiens

GOA IEI010823 Protein protein interactors of human gene QPCTL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene QPCTL (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX019949 GO:0021542 biological process dentate gyrus development The process whose specific outcome is the progression of the dentate gyrus over time, from its forma (more detail) 16 NA Homo sapiens

GOA IEI003666 Protein protein interactors of human gene DNAJC13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJC13 (SwissProt I (more detail) 16 17535438 Homo sapiens

I2D IEI012615 Protein protein interactors of human gene SMG5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMG5 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D MOX017778 Genes associated with Computational Drug Signature SULFALENE Genes associated with Computational Drug Signature SULFALENE, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB MOX002562 Genes associated with Computational Drug Signature Fluazinam Genes associated with Computational Drug Signature Fluazinam, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB MOX005136 Genes associated with Computational Drug Signature Ethene Genes associated with Computational Drug Signature Ethene, curated by the Drug Signature Database (D (more detail) 16 25990557 Homo sapiens

DSigDB MEX003832 Genes associated with Perturbagen Signature PF 00875133 00 Genes associated with Perturbagen Signature PF-00875133-00, curated by the Drug Signature Database ( (more detail) 16 25990557 Homo sapiens

DSigDB TAX000485 Genes annotated by the GO term GO:0045787. Any process that activates or increases the rate or extent of progression through the cell cycle. (more detail) 16 NA Homo sapiens

MSigDB WIG000660 Genes involved in Activation of BH3 only proteins (more detail) 16 NA Homo sapiens

MSigDB MEX001468 Genes associated with Kinase Inhibitor Kinome 1242 Genes associated with Kinase Inhibitor Kinome_1242, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB WIG001089 Genes involved in Platelet sensitization by LDL (more detail) 16 NA Homo sapiens

MSigDB FEX001894 Lung Chen07 16genes Table 1. Hazard Ratios for Death from Any Cause for the 125 Patients with NSCLC and Results of Valid (more detail) 16 17202451 Homo sapiens

GeneSigDB TAX000217 Genes annotated by the GO term GO:0007292. The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. (more detail) 16 NA Homo sapiens

MSigDB MOX005520 Genes associated with Computational Drug Signature 172889 27 9 Genes associated with Computational Drug Signature 172889-27-9, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB FEX001820 Lung Yuan04 16genes Table 1b. Alterations in Gene Expression in NCI-H522 Cells Treated by 5-Aza-dC: Genes upregulated by (more detail) 16 15256063 Homo sapiens

GeneSigDB PEX002109 KH 1: KH domain KH motifs bind RNA in vitro. Autoantibodies to Nova, a KH domain protein, cause paraneoplastic opsoc (more detail) 16 NA Homo sapiens

Pfam TAX014043 GO:0002070 biological process epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epit (more detail) 16 NA Homo sapiens

GOA TAX015326 GO:0004697 molecular function protein kinase C activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylgl (more detail) 16 NA Homo sapiens

GOA WAG001484 EPHA2 forward signaling (more detail) 16 NA Homo sapiens

NCI-Nature Curated WAG000034 Glypican 1 network (more detail) 16 NA Homo sapiens

NCI-Nature Curated MOX001423 Genes associated with Computational Drug Signature phthalic acid Genes associated with Computational Drug Signature phthalic acid, curated by the Drug Signature Data (more detail) 16 25990557 Homo sapiens

DSigDB MOX000280 Genes associated with Computational Drug Signature p Propenylanisole Genes associated with Computational Drug Signature p-Propenylanisole, curated by the Drug Signature (more detail) 16 25990557 Homo sapiens

DSigDB TAX029495 GO:0071481 biological process cellular response to X ray Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 11 NA Homo sapiens

GOA TAX028917 GO:0070411 molecular function I SMAD binding Interacting selectively and non-covalently with an inhibitory SMAD signaling protein. (more detail) 11 NA Homo sapiens

GOA TAX022009 GO:0033160 biological process positive regulation of protein import into nucleus, translocation Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into (more detail) 11 NA Homo sapiens

GOA TAX022048 GO:0033234 biological process negative regulation of protein sumoylation Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO g (more detail) 11 NA Homo sapiens

GOA TAX030321 GO:0090085 biological process regulation of protein deubiquitination Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiq (more detail) 11 NA Homo sapiens

GOA TAX024928 GO:0045073 biological process regulation of chemokine biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 11 NA Homo sapiens

GOA TAX025181 GO:0045628 biological process regulation of T helper 2 cell differentiation Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation. (more detail) 11 NA Homo sapiens

GOA TAX034254 GO:1990440 biological process positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress Any process that activates or increases the frequency, rate or extent of transcription from an RNA p (more detail) 11 NA Homo sapiens

GOA TAX032735 GO:1902992 biological process negative regulation of amyloid precursor protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor prote (more detail) 11 NA Homo sapiens

GOA IEI014439 Protein protein interactors of human gene TTF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTF1 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI014876 Protein protein interactors of human gene VGLL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VGLL4 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D TAX019028 GO:0016442 cellular component RISC complex A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfe (more detail) 11 NA Homo sapiens

GOA TAX021301 GO:0032041 molecular function NAD dependent histone deacetylase activity (H3 K14 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine ( (more detail) 11 NA Homo sapiens

GOA TAX027747 GO:0060218 biological process hematopoietic stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hematopoieti (more detail) 11 NA Homo sapiens

GOA TAX021471 GO:0032351 biological process negative regulation of hormone metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 11 NA Homo sapiens

GOA TAX029261 GO:0071027 biological process nuclear RNA surveillance The set of processes involved in identifying and degrading defective or aberrant RNAs within the nuc (more detail) 11 NA Homo sapiens

GOA TAX018178 GO:0010870 biological process positive regulation of receptor biosynthetic process Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is (more detail) 11 NA Homo sapiens

GOA TAX024460 GO:0043586 biological process tongue development The process whose specific outcome is the progression of the tongue over time, from its formation to (more detail) 11 NA Homo sapiens

GOA TAX021596 GO:0032494 biological process response to peptidoglycan Any process that results in a change in state or activity of an organism (in terms of movement, secr (more detail) 11 NA Homo sapiens

GOA TAX025365 GO:0045945 biological process positive regulation of transcription by RNA polymerase III Any process that activates or increases the frequency, rate or extent of transcription mediated by R (more detail) 11 NA Homo sapiens

GOA TAX027301 GO:0051974 biological process negative regulation of telomerase activity Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reac (more detail) 11 NA Homo sapiens

GOA TAX020932 GO:0031332 cellular component RNAi effector complex Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most kno (more detail) 11 NA Homo sapiens

GOA TAX032879 GO:1903299 biological process regulation of hexokinase activity Any process that modulates the frequency, rate or extent of hexokinase activity. (more detail) 11 NA Homo sapiens

GOA TAX035020 GO:2001034 biological process positive regulation of double strand break repair via nonhomologous end joining Any process that activates or increases the frequency, rate or extent of double-strand break repair (more detail) 11 NA Homo sapiens

GOA TAX032567 GO:1902572 biological process negative regulation of serine type peptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase a (more detail) 11 NA Homo sapiens

GOA TAX032014 GO:1901096 biological process regulation of autophagosome maturation Any process that modulates the frequency, rate or extent of autophagosome maturation. (more detail) 11 NA Homo sapiens

GOA IEI004861 Protein protein interactors of human gene FOXC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXC1 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI005576 Protein protein interactors of human gene GTF2A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2A2 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI005971 Protein protein interactors of human gene HOXB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXB1 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D TAX022759 GO:0035195 biological process gene silencing by miRNA Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleot (more detail) 11 NA Homo sapiens

GOA TAX031330 GO:0099149 biological process regulation of postsynaptic neurotransmitter receptor internalization Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor (more detail) 11 NA Homo sapiens

GOA TAX029282 GO:0071073 biological process positive regulation of phospholipid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 11 NA Homo sapiens

GOA TAX024380 GO:0043471 biological process regulation of cellular carbohydrate catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways res (more detail) 11 NA Homo sapiens

GOA TAX024592 GO:0044090 biological process positive regulation of vacuole organization Any process that activates or increases the frequency, rate or extent of a process involved in the f (more detail) 11 NA Homo sapiens

GOA TAX034367 GO:1990825 molecular function sequence specific mRNA binding Interacting selectively and non-covalently with messenger RNA (mRNA) of a specific nucleotide compos (more detail) 11 NA Homo sapiens

GOA TAX034391 GO:1990907 cellular component beta catenin TCF complex A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhanc (more detail) 11 NA Homo sapiens

GOA TAX033422 GO:1904385 biological process cellular response to angiotensin \ (more detail) 11 NA Homo sapiens

GOA TAX027877 GO:0060394 biological process negative regulation of pathway restricted SMAD protein phosphorylation Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphor (more detail) 11 NA Homo sapiens

GOA IEI015481 Protein protein interactors of human gene ZNF318 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF318 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI009536 Protein protein interactors of human gene PAX9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAX9 (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D IEI003603 Protein protein interactors of human gene DLX5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLX5 (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D IEI010281 Protein protein interactors of human gene POU3F2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POU3F2 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI000846 Protein protein interactors of human gene ARHGEF25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARHGEF25 (SwissProt (more detail) 11 17535438 Homo sapiens

I2D TAX027742 GO:0060213 biological process positive regulation of nuclear transcribed mRNA poly(A) tail shortening Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-tra (more detail) 11 NA Homo sapiens

GOA TAX018180 GO:0010872 biological process regulation of cholesterol esterification Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol (more detail) 11 NA Homo sapiens

GOA TAX024476 GO:0043619 biological process regulation of transcription from RNA polymerase II promoter in response to oxidative stress Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a (more detail) 11 NA Homo sapiens

GOA TAX025327 GO:0045899 biological process positive regulation of RNA polymerase II transcriptional preinitiation complex assembly Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcrip (more detail) 11 NA Homo sapiens

GOA TAX020794 GO:0031078 molecular function histone deacetylase activity (H3 K14 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine ( (more detail) 11 NA Homo sapiens

GOA TAX025236 GO:0045722 biological process positive regulation of gluconeogenesis Any process that activates or increases the frequency, rate or extent of gluconeogenesis. (more detail) 11 NA Homo sapiens

GOA TAX028135 GO:0060788 biological process ectodermal placode formation The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickenin (more detail) 11 NA Homo sapiens

GOA IEI005598 Protein protein interactors of human gene GTPBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTPBP1 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI005975 Protein protein interactors of human gene HOXB4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXB4 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI012617 Protein protein interactors of human gene SMG7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMG7 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI013771 Protein protein interactors of human gene TLX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLX1 (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D IEI007482 Protein protein interactors of human gene LSR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSR (SwissProt ID=Q8 (more detail) 11 17535438 Homo sapiens

I2D TAX034478 GO:2000105 biological process positive regulation of DNA dependent DNA replication Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replicati (more detail) 11 NA Homo sapiens

GOA TAX028665 GO:0062042 biological process regulation of cardiac epithelial to mesenchymal transition Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transi (more detail) 11 NA Homo sapiens

GOA IEI009526 Protein protein interactors of human gene PATZ1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PATZ1 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI005986 Protein protein interactors of human gene HOXC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXC6 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI014428 Protein protein interactors of human gene TTC37 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTC37 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI001628 Protein protein interactors of human gene C5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C5 (SwissProt ID=P01 (more detail) 11 17535438 Homo sapiens

I2D TAX027740 GO:0060211 biological process regulation of nuclear transcribed mRNA poly(A) tail shortening Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-tra (more detail) 11 NA Homo sapiens

GOA TAX022994 GO:0035631 cellular component CD40 receptor complex A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor (more detail) 11 NA Homo sapiens

GOA TAX023607 GO:0040015 biological process negative regulation of multicellular organism growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism (more detail) 11 NA Homo sapiens

GOA TAX020834 GO:0031125 biological process rRNA 3' end processing Any process involved in forming the mature 3' end of an rRNA molecule. (more detail) 11 NA Homo sapiens

GOA TAX031757 GO:1900004 biological process negative regulation of serine type endopeptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptida (more detail) 11 NA Homo sapiens

GOA TAX033826 GO:1905214 biological process regulation of RNA binding Any process that modulates the frequency, rate or extent of RNA binding. (more detail) 11 NA Homo sapiens

GOA IEI000215 Protein protein interactors of human gene ADAM12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADAM12 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI011334 Protein protein interactors of human gene RIPK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RIPK4 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI006489 Protein protein interactors of human gene IRF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IRF6 (SwissProt ID=O (more detail) 11 17535438 Homo sapiens

I2D TAX023882 GO:0042535 biological process positive regulation of tumor necrosis factor biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 11 NA Homo sapiens

GOA TAX022049 GO:0033235 biological process positive regulation of protein sumoylation Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups (more detail) 11 NA Homo sapiens

GOA TAX017810 GO:0009931 molecular function calcium dependent protein serine/threonine kinase activity Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a pro (more detail) 11 NA Homo sapiens

GOA TAX026312 GO:0048712 biological process negative regulation of astrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiat (more detail) 11 NA Homo sapiens

GOA TAX019637 GO:0019211 molecular function phosphatase activator activity Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate gro (more detail) 11 NA Homo sapiens

GOA TAX024627 GO:0044213 molecular function intronic transcription regulatory region DNA binding Interacting selectively and non-covalently with an intronic DNA region that regulates the transcript (more detail) 11 NA Homo sapiens

GOA TAX028798 GO:0070203 biological process regulation of establishment of protein localization to telomere Any process that modulates the frequency, rate or extent of the directed movement of a protein to a (more detail) 11 NA Homo sapiens

GOA IEI009703 Protein protein interactors of human gene PDLIM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDLIM2 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D WEX000100 TH9 Differentiation The genes related to th9 differentiation (adaptive immunity) in immune using next-generation sequenc (more detail) 11 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI006961 Protein protein interactors of human gene KLK9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLK9 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D TAX023880 GO:0042532 biological process negative regulation of tyrosine phosphorylation of STAT protein Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a (more detail) 11 NA Homo sapiens

GOA TAX021764 GO:0032769 biological process negative regulation of monooxygenase activity Any process that stops or reduces the activity of a monooxygenase. (more detail) 11 NA Homo sapiens

GOA TAX000504 Genes annotated by the GO term GO:0043410. Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. (more detail) 11 NA Homo sapiens

MSigDB MOX002281 Genes associated with Computational Drug Signature Eldecalcitol Genes associated with Computational Drug Signature Eldecalcitol, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens

DSigDB MOX017076 Genes associated with Computational Drug Signature 2,4 Dinitrofluorobenzene Genes associated with Computational Drug Signature 2,4-Dinitrofluorobenzene, curated by the Drug Sig (more detail) 11 25990557 Homo sapiens

DSigDB WIG001004 Genes involved in mTORC1 mediated signalling (more detail) 11 NA Homo sapiens

MSigDB TAX000634 Genes annotated by the GO term GO:0045072. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon gamma. (more detail) 11 NA Homo sapiens

MSigDB TAX016266 GO:0006346 biological process methylation dependent chromatin silencing Repression of transcription by methylation of DNA, leading to the formation of heterochromatin. (more detail) 11 NA Homo sapiens

GOA TAX000496 Genes annotated by the GO term GO:0051054. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA. (more detail) 11 NA Homo sapiens

MSigDB MOX001221 Genes associated with Computational Drug Signature Cadmium telluride Genes associated with Computational Drug Signature Cadmium telluride, curated by the Drug Signature (more detail) 11 25990557 Homo sapiens

DSigDB WIG000411 Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle Sonic Hedgehog (Shh) is a secreted protein identified genetically as an important developmental fact (more detail) 11 NA Homo sapiens

MSigDB WAG000850 mechanisms of transcriptional repression by dna methylation Tumorigenesis is known to be a multistep process in which defects in various cancer genes accumulate (more detail) 11 NA Homo sapiens

BioCarta TAX000095 Genes annotated by the GO term GO:0043624. The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups. (more detail) 11 NA Homo sapiens

MSigDB WIG000308 Map Kinase Inactivation of SMRT Corepressor Corepressors are coregulators that interact with transcriptional silencers in a variety of pathways (more detail) 11 NA Homo sapiens

MSigDB MAX002130 Genes within amplicon 7p15 identified in a copy number alterations study of 191 breast tumor samples. A single cancer cell contains large numbers of genetic alterations that in combination create the ma (more detail) 11 NA Homo sapiens

MSigDB WIG001757 Murine MSP STK Signaling Murine MSP-STK Signaling (more detail) 11 NA Homo sapiens

Protein Lounge MOX003071 Genes associated with Computational Drug Signature 5,6 Dichloro 1H benzimidazole Genes associated with Computational Drug Signature 5,6-Dichloro-1H-benzimidazole, curated by the Dru (more detail) 11 25990557 Homo sapiens

DSigDB TAX017918 GO:0010454 biological process negative regulation of cell fate commitment Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate (more detail) 11 NA Homo sapiens

GOA MOX014978 Genes associated with Computational Drug Signature Saracatinib Genes associated with Computational Drug Signature Saracatinib, curated by the Drug Signature Databa (more detail) 11 25990557 Homo sapiens

DSigDB WAG001439 Circadian rhythm Circadian rhythm is an interl biological clock, which ebles to sustain an approximately 24-hour rhyt (more detail) 11 NA Homo sapiens

KEGG WIG000737 Genes involved in CD28 dependent Vav1 pathway (more detail) 11 NA Homo sapiens

MSigDB TAX013642 GO:0001206 molecular function distal enhancer DNA binding transcription repressor activity, RNA polymerase II specific A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA (more detail) 11 NA Homo sapiens

GOA WIG000999 Genes involved in mRNA Decay by 3' to 5' Exoribonuclease (more detail) 11 NA Homo sapiens

MSigDB MOX003489 Genes associated with Computational Drug Signature WP1066 Genes associated with Computational Drug Signature WP1066, curated by the Drug Signature Database (D (more detail) 11 25990557 Homo sapiens

DSigDB MOX003038 Genes associated with Computational Drug Signature pd 158780 Genes associated with Computational Drug Signature pd 158780, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens

DSigDB TAX018425 GO:0014902 biological process myotube differentiation The process in which a relatively unspecialized cell acquires specialized features of a myotube cell (more detail) 11 NA Homo sapiens

GOA TAX013862 GO:0001823 biological process mesonephros development The process whose specific outcome is the progression of the mesonephros over time, from its formati (more detail) 11 NA Homo sapiens

GOA TAX013627 GO:0001161 molecular function intronic transcription regulatory region sequence specific DNA binding Interacting selectively and non-covalently with an intronic DNA sequence that regulates the transcri (more detail) 11 NA Homo sapiens

GOA TAX013347 GO:0000288 biological process nuclear transcribed mRNA catabolic process, deadenylation dependent decay A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordere (more detail) 11 NA Homo sapiens

GOA TAX018364 GO:0014745 biological process negative regulation of muscle adaptation Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. (more detail) 11 NA Homo sapiens

GOA TAX014637 GO:0003207 biological process cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac chamber from unspecified (more detail) 11 NA Homo sapiens

GOA WAG001040 transcription regulation by methyltransferase of carm1 Several forms of post-translatiol modification regulate protein activities. Recently, protein methy (more detail) 11 NA Homo sapiens

BioCarta TAX001135 Genes annotated by the GO term GO:0019213. Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. (more detail) 11 NA Homo sapiens

MSigDB WIG000283 Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway Map kinases transduce responses to extracellular signals by a variety of routes, and communicate wit (more detail) 11 NA Homo sapiens

MSigDB WIG000368 Reversal of Insulin Resistance by Leptin The insulin resistance of type II diabetes appears to be caused in part by the presence of high leve (more detail) 11 NA Homo sapiens

MSigDB TAX000623 Genes annotated by the GO term GO:0032583. Any process that modulates the DNA dependent transcription of a specific gene or genes. (more detail) 11 NA Homo sapiens

MSigDB MOX003005 Genes associated with Computational Drug Signature Perifosine Genes associated with Computational Drug Signature Perifosine, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens

DSigDB MOX009947 Genes associated with Computational Drug Signature CHEMBL380598 Genes associated with Computational Drug Signature CHEMBL380598, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens

DSigDB MOX012824 Genes associated with Computational Drug Signature Gefitinib Genes associated with Computational Drug Signature Gefitinib, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens

DSigDB TAX017216 GO:0008349 molecular function MAP kinase kinase kinase kinase activity Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kin (more detail) 11 NA Homo sapiens

GOA TAX018100 GO:0010759 biological process positive regulation of macrophage chemotaxis Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemot (more detail) 11 NA Homo sapiens

GOA TAX000285 Genes annotated by the GO term GO:0032623. The appearance of interleukin 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. (more detail) 11 NA Homo sapiens

MSigDB WIG000004 ALK2 signaling events (more detail) 11 NA Homo sapiens

MSigDB MOX002475 Genes associated with Computational Drug Signature (5 methyl 3 (morpholinomethyl) 2,3 dihydro [1,4]oxazino[2,3,4 hi]indol 6 yl)(naphthalen 1 yl)methanone Genes associated with Computational Drug Signature (5-methyl-3-(morpholinomethyl)-2,3-dihydro-[1,4]o (more detail) 11 25990557 Homo sapiens

DSigDB TAX014517 GO:0002921 biological process negative regulation of humoral immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune resp (more detail) 11 NA Homo sapiens

GOA TAX030335 GO:0090103 biological process cochlea morphogenesis The process in which the cochlea is generated and organized. (more detail) 24 NA Homo sapiens

GOA IEI006079 Protein protein interactors of human gene HSPB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSPB2 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI002316 Protein protein interactors of human gene CELF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CELF1 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI008458 Protein protein interactors of human gene MYLK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYLK (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D TAX025109 GO:0045445 biological process myoblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A (more detail) 24 NA Homo sapiens

GOA TAX033072 GO:1903671 biological process negative regulation of sprouting angiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis. (more detail) 24 NA Homo sapiens

GOA TAX027837 GO:0060343 biological process trabecula formation The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue e (more detail) 24 NA Homo sapiens

GOA TAX034922 GO:2000778 biological process positive regulation of interleukin 6 secretion Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion. (more detail) 24 NA Homo sapiens

GOA IEI015150 Protein protein interactors of human gene YEATS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YEATS2 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D IEI000339 Protein protein interactors of human gene AFF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AFF4 (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D IEI015173 Protein protein interactors of human gene YTHDF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YTHDF1 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D IEI009541 Protein protein interactors of human gene PBK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PBK (SwissProt ID=Q9 (more detail) 24 17535438 Homo sapiens

I2D IEI000777 Protein protein interactors of human gene ARAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARAP1 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D TAX023381 GO:0036442 molecular function proton exporting ATPase activity Enables the transfer of protons from one side of a membrane to the other according to the reaction: (more detail) 24 NA Homo sapiens

GOA IEI009715 Protein protein interactors of human gene PDS5B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDS5B (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI011731 Protein protein interactors of human gene RYR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RYR2 (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D IEI007330 Protein protein interactors of human gene LMNB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LMNB2 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D TAX021965 GO:0033081 biological process regulation of T cell differentiation in thymus Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus. (more detail) 24 NA Homo sapiens

GOA IEI015585 Protein protein interactors of human gene ZNF510 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF510 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D IEI003513 Protein protein interactors of human gene DGKZ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DGKZ (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D MEX002139 Genes associated with Kinase Inhibitor JAK Inhibitor I Genes associated with Kinase Inhibitor JAK Inhibitor I, curated by the Drug Signature Database (DSig (more detail) 24 25990557 Homo sapiens

DSigDB MOX017392 Genes associated with Computational Drug Signature ALENDRONATE SODIUM Genes associated with Computational Drug Signature ALENDRONATE SODIUM, curated by the Drug Signature (more detail) 24 25990557 Homo sapiens

DSigDB FEX000682 Breast Burga09 25genes Table 2. Selected genes and pathways that are differentially expressed between BRCA1-mutated and nor (more detail) 24 19190334 Homo sapiens

GeneSigDB WIG001555 IL 10 Pathway IL-10 Pathway (more detail) 24 NA Homo sapiens

Protein Lounge FEX001061 HeadandNeck Sok03 31genes Table 3d. Gene Descriptions of HNSCCA(head and neck squamous cell carcinomas)-related genes with P (more detail) 24 12874079 Homo sapiens

GeneSigDB MEX000154 Genes associated with Approved Drug haloprogin Genes associated with Approved Drug haloprogin, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB MOX017936 Genes associated with Computational Drug Signature Pazopanib hydrochloride Genes associated with Computational Drug Signature Pazopanib hydrochloride, curated by the Drug Sign (more detail) 24 25990557 Homo sapiens

DSigDB MOX013531 Genes associated with Computational Drug Signature LY 367,265 Genes associated with Computational Drug Signature LY-367,265, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens

DSigDB WIG000306 Erk and PI 3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia Activation of the MAPK kinase pathway has been identified as a mechanism that integrins use to regul (more detail) 24 NA Homo sapiens

MSigDB MOX001029 Genes associated with Computational Drug Signature Cryptolepine Genes associated with Computational Drug Signature Cryptolepine, curated by the Drug Signature Datab (more detail) 24 25990557 Homo sapiens

DSigDB MOX002177 Genes associated with Computational Drug Signature jasplakinolide Genes associated with Computational Drug Signature jasplakinolide, curated by the Drug Signature Dat (more detail) 24 25990557 Homo sapiens

DSigDB MOX007261 Genes associated with Computational Drug Signature beta Lapachone Genes associated with Computational Drug Signature beta-Lapachone, curated by the Drug Signature Dat (more detail) 24 25990557 Homo sapiens

DSigDB TAX001338 Genes annotated by the GO term GO:0004722. Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate. (more detail) 24 NA Homo sapiens

MSigDB MOX003346 Genes associated with Computational Drug Signature Tozasertib Genes associated with Computational Drug Signature Tozasertib, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens

DSigDB TAX023113 GO:0035850 biological process epithelial cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional (more detail) 18 NA Homo sapiens

GOA IEI014814 Protein protein interactors of human gene UTP18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UTP18 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI008581 Protein protein interactors of human gene NAT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NAT2 (SwissProt ID=P (more detail) 18 17535438 Homo sapiens

I2D TAX025203 GO:0045655 biological process regulation of monocyte differentiation Any process that modulates the frequency, rate or extent of monocyte differentiation. (more detail) 18 NA Homo sapiens

GOA TAX025686 GO:0046641 biological process positive regulation of alpha beta T cell proliferation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell prolifera (more detail) 18 NA Homo sapiens

GOA TAX022544 GO:0034587 biological process piRNA metabolic process The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nuc (more detail) 18 NA Homo sapiens

GOA TAX021334 GO:0032095 biological process regulation of response to food Any process that modulates the frequency, rate or extent of a response to a food stimulus. (more detail) 18 NA Homo sapiens

GOA TAX023193 GO:0035994 biological process response to muscle stretch Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 18 NA Homo sapiens

GOA TAX023266 GO:0036120 biological process cellular response to platelet derived growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 18 NA Homo sapiens

GOA TAX017356 GO:0008585 biological process female gonad development The process whose specific outcome is the progression of the female gonad over time, from its format (more detail) 18 NA Homo sapiens

GOA IEI014815 Protein protein interactors of human gene UTP20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UTP20 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI007310 Protein protein interactors of human gene LITAF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LITAF (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D TAX033979 GO:1905562 biological process regulation of vascular endothelial cell proliferation Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation. (more detail) 18 NA Homo sapiens

GOA TAX025002 GO:0045190 biological process isotype switching The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immuno (more detail) 18 NA Homo sapiens

GOA TAX034873 GO:2000696 biological process regulation of epithelial cell differentiation involved in kidney development Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved (more detail) 18 NA Homo sapiens

GOA TAX035035 GO:2001057 biological process reactive nitrogen species metabolic process The chemical reactions and pathways involving a reactive nitrogen species. (more detail) 18 NA Homo sapiens

GOA TAX033574 GO:1904706 biological process negative regulation of vascular smooth muscle cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle (more detail) 18 NA Homo sapiens

GOA TAX024918 GO:0045061 biological process thymic T cell selection The process of T cell selection that occurs in the thymus. (more detail) 18 NA Homo sapiens

GOA TAX024104 GO:0043011 biological process myeloid dendritic cell differentiation The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocomp (more detail) 18 NA Homo sapiens

GOA TAX026058 GO:0048103 biological process somatic stem cell division The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of t (more detail) 18 NA Homo sapiens

GOA IEI002730 Protein protein interactors of human gene CNOT10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNOT10 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI001067 Protein protein interactors of human gene ATP1B3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP1B3 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI003849 Protein protein interactors of human gene DUSP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP3 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D FEX000107 BoneMarrow Abraham05 20genes Table 5. Genes with significantly lower average gene expression in AL plasma cells than in MM cells (more detail) 18 15388584 Homo sapiens

GeneSigDB MOX002810 Genes associated with Computational Drug Signature 1,1,2,2,3,3 hexabromocyclododecane Genes associated with Computational Drug Signature 1,1,2,2,3,3-hexabromocyclododecane, curated by th (more detail) 18 25990557 Homo sapiens

DSigDB TAX000150 Genes annotated by the GO term GO:0050663. The regulated release of cytokines from a cell or group of cells. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. (more detail) 18 NA Homo sapiens

MSigDB WAG000230 egf signaling pathway The epidermal growth factor (EGF) peptide induces cellular proliferation through the EGF receptor, w (more detail) 18 NA Homo sapiens

BioCarta TAX014116 GO:0002208 biological process somatic diversification of immunoglobulins involved in immune response The somatic process that results in the generation of sequence diversity of immunoglobulins after in (more detail) 18 NA Homo sapiens

GOA TAX014115 GO:0002204 biological process somatic recombination of immunoglobulin genes involved in immune response The process in which immunoglobulin genes are formed through recombination of the germline genetic e (more detail) 18 NA Homo sapiens

GOA MOX007049 Genes associated with Computational Drug Signature apomorphine Genes associated with Computational Drug Signature apomorphine, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens

DSigDB TAX000789 Genes annotated by the GO term GO:0006383. The synthesis of RNA from a DNA template by RNA polymerase III (Pol III), originating at a Pol III specific promoter. (more detail) 18 NA Homo sapiens

MSigDB MAX001142 Genes distinguishing between breast cancer tumors bearing mutations in BRCA1 [GeneID=672] and those with mutated BRCA2 [GeneID=675]. Tumors arising in BRCA1 and BRCA2 mutation carriers appear to have specific pathological and gene ex (more detail) 18 NA Homo sapiens

MSigDB FEX003418 Viral Stoff Khalili06 19genes Table 3 Descriptive microarray results of apoptosis genes unique to human liver tissue slices that w (more detail) 18 16410819 Homo sapiens

GeneSigDB MOX002636 Genes associated with Computational Drug Signature Rubitecan Genes associated with Computational Drug Signature Rubitecan, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB MEX001999 Genes associated with Kinase Inhibitor Quizartinib Genes associated with Kinase Inhibitor Quizartinib, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB TAX016725 GO:0007004 biological process telomere maintenance via telomerase The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase. (more detail) 18 NA Homo sapiens

GOA MEX002297 Genes associated with Kinase Inhibitor ( ) Epigallocatechin gallate Genes associated with Kinase Inhibitor (-)-Epigallocatechin gallate, curated by the Drug Signature D (more detail) 18 25990557 Homo sapiens

DSigDB MOX006461 Genes associated with Computational Drug Signature A 443654 Genes associated with Computational Drug Signature A-443654, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB WAG001451 hypoxia and p53 in the cardiovascular system Hypoxic stress, like D damage, induces p53 protein accumulation and p53-dependent apoptosis in oncog (more detail) 18 NA Homo sapiens

BioCarta MOX015470 Genes associated with Computational Drug Signature teniposide Genes associated with Computational Drug Signature teniposide, curated by the Drug Signature Databas (more detail) 18 25990557 Homo sapiens

DSigDB WIG002041 Serotonin Receptor 4/6/7 and NR3C Signaling Serotonin Receptor 4/6/7 and NR3C Signaling (more detail) 18 NA Homo sapiens

WikiPathway MEX002234 Genes associated with Kinase Inhibitor czc 25146 Genes associated with Kinase Inhibitor czc-25146, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB WIG000433 Sprouty regulation of tyrosine kinase signals Four different members of the Sprouty protein family block the cellular proliferation and differenti (more detail) 18 NA Homo sapiens

MSigDB MAX003266 Genes in cluster 2: moderately up regulated in HFW cells (fibroblast) upon treatment with sodium arsenite [PubChem=26435] at all time points. Arsenic compounds are widely distributed and arsenic ingestion is associated with many human disease (more detail) 18 NA Homo sapiens

MSigDB WIG000274 Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy One of responses to increased blood pressure is cardiac hypertrophy through increased size of ventri (more detail) 18 NA Homo sapiens

MSigDB MAX001721 Top genes up regulated in the GIST (gastrointestinal stromal tumor) cell line sensitive to imatinib [PubChem=5291] after treatment with MP470, a protein kinase inhibitor. KIT or alpha-platelet-derived growth factor receptor (alpha-PDGFR) activating mutations are the path (more detail) 18 NA Homo sapiens

MSigDB FEX002205 Lymphoma Martinez03 23genes Table 2 Apoptosis-related genes deregulated in MCL (more detail) 18 14678979 Homo sapiens

GeneSigDB FEX002371 MesenchymalStemCells Rider08 21genes Table 1. Stem cell self-renewal and maintenance gene expression in bone marrow-derived mesenchymal s (more detail) 18 18356575 Homo sapiens

GeneSigDB MOX016605 Genes associated with Computational Drug Signature Crizotinib Genes associated with Computational Drug Signature Crizotinib, curated by the Drug Signature Databas (more detail) 22 25990557 Homo sapiens

DSigDB WAG000215 regulation of bad phosphorylation The function of the pro-apoptotic molecule BAD is regulated by phosphorylation of three sites (ser 1 (more detail) 22 NA Homo sapiens

BioCarta WIG000289 Apoptotic Signaling in Response to DNA Damage The cellular activation of the caspase cascade resulting in cell death is triggered by chemical dama (more detail) 22 NA Homo sapiens

MSigDB WAG001343 RNA Polymerase III Transcription Initiation From Type 3 Promoter (more detail) 22 NA Homo sapiens

Reactome FEX000054 Bone Ohali04 23genes Table 2. Selected down-regulated genes in the microarray-based poor prognosis signature ES patients (more detail) 22 15467746 Homo sapiens

GeneSigDB MOX017812 Genes associated with Computational Drug Signature gemfibrozil Genes associated with Computational Drug Signature gemfibrozil, curated by the Drug Signature Databa (more detail) 22 25990557 Homo sapiens

DSigDB TAX014160 GO:0002292 biological process T cell differentiation involved in immune response The process in which an antigenically naive T cell acquires the specialized features of an effector, (more detail) 22 NA Homo sapiens

GOA MOX015586 Genes associated with Computational Drug Signature Tozasertib Genes associated with Computational Drug Signature Tozasertib, curated by the Drug Signature Databas (more detail) 22 25990557 Homo sapiens

DSigDB MOX003646 Genes associated with Computational Drug Signature aldrin Genes associated with Computational Drug Signature aldrin, curated by the Drug Signature Database (D (more detail) 22 25990557 Homo sapiens

DSigDB MEX001972 Genes associated with Kinase Inhibitor 722544 51 6 Genes associated with Kinase Inhibitor 722544-51-6, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB TAX000669 Genes annotated by the GO term GO:0050708. Any process that modulates the frequency, rate or extent of the regulated release of a protein from a cell or group of cells. (more detail) 22 NA Homo sapiens

MSigDB WIG000841 Genes involved in FGFR ligand binding and activation (more detail) 22 NA Homo sapiens

MSigDB WIG000141 PDGFR alpha signaling pathway (more detail) 22 NA Homo sapiens

MSigDB WIG000354 IL 2 signaling pathway Interleukin 2 (IL-2) is a potent cytokine that can lead to cellular activation and proliferation. IL (more detail) 22 NA Homo sapiens

MSigDB WIG000888 Genes involved in GRB2 events in ERBB2 signaling (more detail) 22 NA Homo sapiens

MSigDB WAG001464 multi step regulation of transcription by pitx2 Many transcription factors play essential roles in normal development by determining the proliferati (more detail) 22 NA Homo sapiens

BioCarta MOX003995 Genes associated with Computational Drug Signature dimethoate Genes associated with Computational Drug Signature dimethoate, curated by the Drug Signature Databas (more detail) 22 25990557 Homo sapiens

DSigDB MOX013718 Genes associated with Computational Drug Signature mifepristone Genes associated with Computational Drug Signature mifepristone, curated by the Drug Signature Datab (more detail) 22 25990557 Homo sapiens

DSigDB IEI002428 Protein protein interactors of human gene CFH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CFH (SwissProt ID=P0 (more detail) 22 17535438 Homo sapiens

I2D TAX022322 GO:0034123 biological process positive regulation of toll like receptor signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor signali (more detail) 22 NA Homo sapiens

GOA IEI000358 Protein protein interactors of human gene AGK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AGK (SwissProt ID=Q5 (more detail) 22 17535438 Homo sapiens

I2D TAX029152 GO:0070861 biological process regulation of protein exit from endoplasmic reticulum Any process that modulates the frequency, rate or extent of the directed movement of proteins from t (more detail) 22 NA Homo sapiens

GOA IEI008069 Protein protein interactors of human gene MMP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MMP3 (SwissProt ID=P (more detail) 22 17535438 Homo sapiens

I2D IEI004705 Protein protein interactors of human gene FEM1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FEM1B (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI009751 Protein protein interactors of human gene PER1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PER1 (SwissProt ID=O (more detail) 22 17535438 Homo sapiens

I2D TAX031825 GO:1900120 biological process regulation of receptor binding Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a (more detail) 22 NA Homo sapiens

GOA TAX030284 GO:0090025 biological process regulation of monocyte chemotaxis Any process that modulates the frequency, rate, or extent of monocyte chemotaxis. (more detail) 22 NA Homo sapiens

GOA IEI004410 Protein protein interactors of human gene FABP5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FABP5 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI012162 Protein protein interactors of human gene SH3RF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH3RF1 (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D IEI010561 Protein protein interactors of human gene PRR20C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRR20C (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D TAX017736 GO:0009648 biological process photoperiodism Any process that results in a change in state or activity of an organism (in terms of movement, secr (more detail) 22 NA Homo sapiens

GOA IEI002740 Protein protein interactors of human gene CNP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNP (SwissProt ID=P0 (more detail) 22 17535438 Homo sapiens

I2D IEI009462 Protein protein interactors of human gene PAK6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAK6 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI006731 Protein protein interactors of human gene KCTD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KCTD1 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI015254 Protein protein interactors of human gene ZC3HC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZC3HC1 (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D IEI011339 Protein protein interactors of human gene RIT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RIT1 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D TAX022212 GO:0033688 biological process regulation of osteoblast proliferation Any process that modulates the frequency, rate or extent of osteoblast proliferation. (more detail) 22 NA Homo sapiens

GOA IEI007219 Protein protein interactors of human gene LEPR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LEPR (SwissProt ID=P (more detail) 22 17535438 Homo sapiens

I2D TAX027073 GO:0051580 biological process regulation of neurotransmitter uptake Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmit (more detail) 20 NA Homo sapiens

GOA IEI010190 Protein protein interactors of human gene POLB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLB (SwissProt ID=P (more detail) 20 17535438 Homo sapiens

I2D TAX021055 GO:0031572 biological process G2 DNA damage checkpoint A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the (more detail) 20 NA Homo sapiens

GOA TAX021492 GO:0032376 biological process positive regulation of cholesterol transport Any process that activates or increases the frequency, rate or extent of the directed movement of ch (more detail) 20 NA Homo sapiens

GOA IEI006293 Protein protein interactors of human gene IL12A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL12A (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI006133 Protein protein interactors of human gene IBTK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IBTK (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI004908 Protein protein interactors of human gene FRMD5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FRMD5 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI004212 Protein protein interactors of human gene EPHB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPHB1 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI003930 Protein protein interactors of human gene EDC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EDC3 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI008615 Protein protein interactors of human gene NCBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCBP2 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX016780 GO:0007095 biological process mitotic G2 DNA damage checkpoint A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M t (more detail) 20 NA Homo sapiens

GOA TAX021489 GO:0032373 biological process positive regulation of sterol transport Any process that activates or increases the frequency, rate or extent of the directed movement of st (more detail) 20 NA Homo sapiens

GOA IEI011473 Protein protein interactors of human gene ROR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ROR2 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI002246 Protein protein interactors of human gene CDK17 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK17 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX026018 GO:0048011 biological process neurotrophin TRK receptor signaling pathway A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surfac (more detail) 20 NA Homo sapiens

GOA IEI013530 Protein protein interactors of human gene TDRD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TDRD3 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI013036 Protein protein interactors of human gene SSX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SSX2 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI010780 Protein protein interactors of human gene PURB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PURB (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI004000 Protein protein interactors of human gene EGR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EGR2 (SwissProt ID=P (more detail) 20 17535438 Homo sapiens

I2D WEX000099 TH2 Differentiation The genes related to th2 differentiation (adaptive immunity) in immune using next-generation sequenc (more detail) 20 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas TAX032195 GO:1901623 biological process regulation of lymphocyte chemotaxis Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis. (more detail) 20 NA Homo sapiens

GOA IEI001248 Protein protein interactors of human gene BBS10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BBS10 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI015367 Protein protein interactors of human gene ZMYM4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZMYM4 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D MOX004670 Genes associated with Computational Drug Signature Sodium salicylate Genes associated with Computational Drug Signature Sodium salicylate, curated by the Drug Signature (more detail) 20 25990557 Homo sapiens

DSigDB WIG001359 Agents Acting on the Renin Angiotensin System Pathway, Pharmacodynamics Genes involved in the pharmacodynamics of the drugs that act on the renin-angiotensin-aldosterone sy (more detail) 20 NA Homo sapiens

PharmGKB TAX000518 Genes annotated by the GO term GO:0051047. Any process that activates or increases the frequency, rate or extent of the regulated release of a substance from a cell or group of cells. (more detail) 20 NA Homo sapiens

MSigDB WAG001453 agrin in postsynaptic differentiation The heparan sulphate proteoglycan agrin is well known as the key assembly factor of postsyptic diffe (more detail) 20 NA Homo sapiens

BioCarta TAX013507 GO:0000803 cellular component sex chromosome A chromosome involved in sex determination. (more detail) 20 NA Homo sapiens

GOA MOX002517 Genes associated with Computational Drug Signature Teriflunomide Genes associated with Computational Drug Signature Teriflunomide, curated by the Drug Signature Data (more detail) 20 25990557 Homo sapiens

DSigDB MOX004209 Genes associated with Computational Drug Signature HYPOCHLOROUS ACID Genes associated with Computational Drug Signature HYPOCHLOROUS ACID, curated by the Drug Signature (more detail) 20 25990557 Homo sapiens

DSigDB TAX016996 GO:0007617 biological process mating behavior The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resu (more detail) 20 NA Homo sapiens

GOA MOX003189 Genes associated with Computational Drug Signature 2,2',4,6,6' pentachlorobiphenyl Genes associated with Computational Drug Signature 2,2',4,6,6'-pentachlorobiphenyl, curated by the D (more detail) 20 25990557 Homo sapiens

DSigDB MAX000390 Genes up regulated in K562 cells (chronic myelogenous leukemia, CML) expressing TP53 and MYC [GeneID=7157;4609]. We have previously demonstrated that c-Myc impairs p53-mediated apoptosis in K562 human leukemia cel (more detail) 20 NA Homo sapiens

MSigDB FEX000509 Breast Korkola07 22genes OverlapGenes Additional File 5d-One excel file listing the gene sets derived from PAM SAM a correlation based t (more detail) 20 17428335 Homo sapiens

GeneSigDB WAG000012 cell cycle: g2/m checkpoint The G2/M D damage checkpoint prevents the cell from entering mitosis (M phase) if the genome is dama (more detail) 20 NA Homo sapiens

BioCarta WIG001405 ACE Inhibitor Pathway, Pharmacodynamics Model, non-tissue-specific cell displaying genes which may be involved in the ACE inhibitor pathway (more detail) 20 NA Homo sapiens

PharmGKB FEX000142 Brain Levy04 32genes Table 2 List of the significantly altered expressed genes in the plexiform neurofibromas relative to (more detail) 20 15173083 Homo sapiens

GeneSigDB TAX000059 Genes annotated by the GO term GO:0042113. The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. (more detail) 20 NA Homo sapiens

MSigDB TAX014204 GO:0002367 biological process cytokine production involved in immune response The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contribu (more detail) 20 NA Homo sapiens

GOA MEX002440 Genes associated with Perturbagen Signature 0198306 0000 Genes associated with Perturbagen Signature 0198306-0000, curated by the Drug Signature Database (DS (more detail) 20 25990557 Homo sapiens

DSigDB WIG001595 Notch Signaling Notch Signaling (more detail) 20 NA Homo sapiens

Protein Lounge MOX001566 Genes associated with Computational Drug Signature bifonazole Genes associated with Computational Drug Signature bifonazole, curated by the Drug Signature Databas (more detail) 20 25990557 Homo sapiens

DSigDB WAG001036 the igf 1 receptor and longevity A demonstrated means to increase lifespan in a wide range of organisms is through the restriction of (more detail) 13 NA Homo sapiens

BioCarta TAX000909 Genes annotated by the GO term GO:0030530. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II, that which is translated into protein) with protein, which is cell specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA. (more detail) 13 NA Homo sapiens

MSigDB MEX001688 Genes associated with Kinase Inhibitor GW575808A Genes associated with Kinase Inhibitor GW575808A, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MOX004155 Genes associated with Computational Drug Signature GOLD Genes associated with Computational Drug Signature GOLD, curated by the Drug Signature Database (DSi (more detail) 13 25990557 Homo sapiens

DSigDB TAX000628 Genes annotated by the GO term GO:0032844. Any process that modulates the frequency, rate, or extent of a homeostatic process. (more detail) 13 NA Homo sapiens

MSigDB MOX000126 Genes associated with Computational Drug Signature 2 Phenylphenol Genes associated with Computational Drug Signature 2-Phenylphenol, curated by the Drug Signature Dat (more detail) 13 25990557 Homo sapiens

DSigDB WIG000422 RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage Cell cycle checkpoint controls at the G1 to S transition and the G2 to M transition prevent the cell (more detail) 13 NA Homo sapiens

MSigDB WAG000241 telomeres telomerase cellular aging and immortality Telomeres, which define the ends of chromosomes, consist of short, tandemly repeated D sequences loo (more detail) 13 NA Homo sapiens

BioCarta TAX001395 Genes annotated by the GO term GO:0003707. Combining with a steroid hormone to initiate a change in cell activity. (more detail) 13 NA Homo sapiens

MSigDB TAX000532 Genes annotated by the GO term GO:0002440. The synthesis or release of any molecular mediator of the immune response following an immunological stimulus, resulting in an increase in its intracellular or extracellular levels. (more detail) 13 NA Homo sapiens

MSigDB TAX013487 GO:0000782 cellular component telomere cap complex A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes (more detail) 13 NA Homo sapiens

GOA TAX015966 GO:0005845 cellular component mRNA cap binding complex Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA. (more detail) 13 NA Homo sapiens

GOA WAG000426 calcium signaling by hbx of hepatitis b virus Hepatitis B is a small D virus that contains only 4 open reading frames in its genome. Three of the (more detail) 13 NA Homo sapiens

BioCarta FEX000337 Breast Man05 15genes ER Table 1. Comparison of gene expression frequencies between ER (-) and ER (+) cells (more detail) 13 15692763 Homo sapiens

GeneSigDB MOX001648 Genes associated with Computational Drug Signature Gadolinium trichloride Genes associated with Computational Drug Signature Gadolinium trichloride, curated by the Drug Signa (more detail) 13 25990557 Homo sapiens

DSigDB MOX003268 Genes associated with Computational Drug Signature Dehydroxymethylepoxyquinomicin Genes associated with Computational Drug Signature Dehydroxymethylepoxyquinomicin, curated by the Dr (more detail) 13 25990557 Homo sapiens

DSigDB TAX014644 GO:0003215 biological process cardiac right ventricle morphogenesis The process in which the right cardiac ventricle is generated and organized. (more detail) 13 NA Homo sapiens

GOA TAX000390 Genes annotated by the GO term GO:0008156. Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication. (more detail) 13 NA Homo sapiens

MSigDB WIG000832 Genes involved in Extrinsic Pathway for Apoptosis (more detail) 13 NA Homo sapiens

MSigDB MEX000727 Genes associated with Approved Drug bexarotene Genes associated with Approved Drug bexarotene, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MEX003842 Genes associated with Perturbagen Signature PHA 00851261E Genes associated with Perturbagen Signature PHA-00851261E, curated by the Drug Signature Database (D (more detail) 13 25990557 Homo sapiens

DSigDB WAG001278 Regulation of cytoplasmic and nuclear SMAD2/3 signaling (more detail) 13 NA Homo sapiens

NCI-Nature Curated MOX014367 Genes associated with Computational Drug Signature Pazopanib Genes associated with Computational Drug Signature Pazopanib, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens

DSigDB TAX000320 Genes annotated by the GO term GO:0032984. The disaggregation of a macromolecular complex into its constituent components. (more detail) 13 NA Homo sapiens

MSigDB TAX000221 Genes annotated by the GO term GO:0000080. Progression through G1 phase, one of two 'gap' phases in the mitotic cell cycle; G1 is the interval between the completion of mitosis and the beginning of DNA synthesis. (more detail) 13 NA Homo sapiens

MSigDB MOX000297 Genes associated with Computational Drug Signature 4 tert Butylphenol Genes associated with Computational Drug Signature 4-tert-Butylphenol, curated by the Drug Signature (more detail) 13 25990557 Homo sapiens

DSigDB TAX016606 GO:0006809 biological process nitric oxide biosynthetic process The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (N (more detail) 13 NA Homo sapiens

GOA TAX013294 GO:0000177 cellular component cytoplasmic exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity pr (more detail) 13 NA Homo sapiens

GOA WIG000258 Oxidative Stress Induced Gene Expression Via Nrf2 Reactive oxygen species (ROS) can damage biological macromolecules and are detrimental to cellular h (more detail) 13 NA Homo sapiens

MSigDB WIG000205 Expression of cyclins regulates progression through the cell cycle by activating cyclin dependent kinases. na (more detail) 13 NA Homo sapiens

MSigDB TAX000528 Genes annotated by the GO term GO:0042102. Any process that activates or increases the rate or extent of T cell proliferation. (more detail) 13 NA Homo sapiens

MSigDB WIG001134 Genes involved in Regulation of Complement cascade (more detail) 13 NA Homo sapiens

MSigDB WIG001947 Keap1 Nrf2 Pathway Keap1-Nrf2 Pathway (more detail) 13 NA Homo sapiens

WikiPathway MOX004873 Genes associated with Computational Drug Signature 3,3' DICHLOROBENZIDINE Genes associated with Computational Drug Signature 3,3'-DICHLOROBENZIDINE, curated by the Drug Signa (more detail) 13 25990557 Homo sapiens

DSigDB MEX001504 Genes associated with Kinase Inhibitor PKCbeta Inhibitor Genes associated with Kinase Inhibitor PKCbeta Inhibitor, curated by the Drug Signature Database (DS (more detail) 13 25990557 Homo sapiens

DSigDB MOX002537 Genes associated with Computational Drug Signature benzo[g][1]benzofuran 8,9 dione Genes associated with Computational Drug Signature benzo[g][1]benzofuran-8,9-dione, curated by the D (more detail) 13 25990557 Homo sapiens

DSigDB TAX013488 GO:0000783 cellular component nuclear telomere cap complex A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects (more detail) 13 NA Homo sapiens

GOA PEX002643 Death: Death domain (more detail) 13 NA Homo sapiens

Pfam IEI009745 Protein protein interactors of human gene PELI3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PELI3 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX033031 GO:1903587 biological process regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferat (more detail) 13 NA Homo sapiens

GOA IEI001298 Protein protein interactors of human gene BCORL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCORL1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D TAX025153 GO:0045591 biological process positive regulation of regulatory T cell differentiation Any process that activates or increases the frequency, rate or extent of differentiation of regulato (more detail) 13 NA Homo sapiens

GOA TAX031809 GO:1900103 biological process positive regulation of endoplasmic reticulum unfolded protein response Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfol (more detail) 13 NA Homo sapiens

GOA IEI003728 Protein protein interactors of human gene DOK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DOK3 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI012748 Protein protein interactors of human gene SOCS5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOCS5 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI007842 Protein protein interactors of human gene MED13L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED13L (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D TAX028026 GO:0060602 biological process branch elongation of an epithelium The growth process in which a branch increases in length from its base to its tip. (more detail) 13 NA Homo sapiens

GOA TAX023946 GO:0042635 biological process positive regulation of hair cycle Any process that activates or increases the frequency, rate or extent of the cyclical phases of grow (more detail) 13 NA Homo sapiens

GOA TAX020105 GO:0021895 biological process cerebral cortex neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron resid (more detail) 13 NA Homo sapiens

GOA IEI002572 Protein protein interactors of human gene CITED1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CITED1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI010345 Protein protein interactors of human gene PPP1R13L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R13L (SwissProt (more detail) 13 17535438 Homo sapiens

I2D IEI013646 Protein protein interactors of human gene TH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TH (SwissProt ID=P07 (more detail) 13 17535438 Homo sapiens

I2D IEI000135 Protein protein interactors of human gene ACKR4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACKR4 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX021108 GO:0031665 biological process negative regulation of lipopolysaccharide mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response (more detail) 13 NA Homo sapiens

GOA TAX023618 GO:0040034 biological process regulation of development, heterochronic Any process that modulates the consistent predetermined time point at which an integrated living uni (more detail) 13 NA Homo sapiens

GOA TAX022788 GO:0035259 molecular function glucocorticoid receptor binding Interacting selectively and non-covalently with a glucocorticoid receptor. (more detail) 13 NA Homo sapiens

GOA TAX029456 GO:0071425 biological process hematopoietic stem cell proliferation The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is (more detail) 13 NA Homo sapiens

GOA TAX020777 GO:0031054 biological process pre miRNA processing Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule. (more detail) 13 NA Homo sapiens

GOA IEI004296 Protein protein interactors of human gene ESCO2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ESCO2 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI011219 Protein protein interactors of human gene RFX3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RFX3 (SwissProt ID=P (more detail) 13 17535438 Homo sapiens

I2D IEI005982 Protein protein interactors of human gene HOXC11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXC11 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI014213 Protein protein interactors of human gene TRIB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIB2 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI014433 Protein protein interactors of human gene TTC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTC5 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D TAX031824 GO:1900119 biological process positive regulation of execution phase of apoptosis Any process that activates or increases the frequency, rate or extent of execution phase of apoptosi (more detail) 13 NA Homo sapiens

GOA IEI008766 Protein protein interactors of human gene NEUROD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEUROD1 (SwissProt I (more detail) 13 17535438 Homo sapiens

I2D IEI012666 Protein protein interactors of human gene SNAPC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNAPC1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D TAX023156 GO:0035925 molecular function mRNA 3' UTR AU rich region binding Interacting selectively and non-covalently with a region containing frequent adenine and uridine bas (more detail) 13 NA Homo sapiens

GOA TAX019450 GO:0018027 biological process peptidyl lysine dimethylation The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine. (more detail) 13 NA Homo sapiens

GOA TAX033598 GO:1904748 biological process regulation of apoptotic process involved in development Any process that modulates the frequency, rate or extent of apoptotic process involved in developmen (more detail) 13 NA Homo sapiens

GOA TAX032480 GO:1902337 biological process regulation of apoptotic process involved in morphogenesis Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogene (more detail) 13 NA Homo sapiens

GOA IEI003328 Protein protein interactors of human gene DCAF12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCAF12 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI004904 Protein protein interactors of human gene FRK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FRK (SwissProt ID=P4 (more detail) 13 17535438 Homo sapiens

I2D IEI001426 Protein protein interactors of human gene BRD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRD3 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D TAX024182 GO:0043142 molecular function single stranded DNA dependent ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of singl (more detail) 13 NA Homo sapiens

GOA IEI003472 Protein protein interactors of human gene DENND4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DENND4A (SwissProt I (more detail) 13 17535438 Homo sapiens

I2D IEI003982 Protein protein interactors of human gene EFNA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFNA5 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI001020 Protein protein interactors of human gene ATF6B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATF6B (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI001461 Protein protein interactors of human gene BTAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BTAF1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX021999 GO:0033147 biological process negative regulation of intracellular estrogen receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an int (more detail) 13 NA Homo sapiens

GOA TAX021722 GO:0032700 biological process negative regulation of interleukin 17 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any mem (more detail) 13 NA Homo sapiens

GOA TAX026083 GO:0048188 cellular component Set1C/COMPASS complex A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex c (more detail) 13 NA Homo sapiens

GOA TAX019937 GO:0021527 biological process spinal cord association neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or (more detail) 13 NA Homo sapiens

GOA TAX019106 GO:0016580 cellular component Sin3 complex A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor (more detail) 13 NA Homo sapiens

GOA TAX025143 GO:0045579 biological process positive regulation of B cell differentiation Any process that activates or increases the frequency, rate or extent of B cell differentiation. (more detail) 13 NA Homo sapiens

GOA TAX025171 GO:0045618 biological process positive regulation of keratinocyte differentiation Any process that activates or increases the frequency, rate or extent of keratinocyte differentiatio (more detail) 13 NA Homo sapiens

GOA IEI015354 Protein protein interactors of human gene ZKSCAN7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZKSCAN7 (SwissProt I (more detail) 13 17535438 Homo sapiens

I2D IEI003075 Protein protein interactors of human gene CSRP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSRP1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI010501 Protein protein interactors of human gene PRKX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRKX (SwissProt ID=P (more detail) 13 17535438 Homo sapiens

I2D IEI013635 Protein protein interactors of human gene TGFBRAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TGFBRAP1 (SwissProt (more detail) 13 17535438 Homo sapiens

I2D IEI000332 Protein protein interactors of human gene AFAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AFAP1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX022317 GO:0034116 biological process positive regulation of heterotypic cell cell adhesion Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhe (more detail) 13 NA Homo sapiens

GOA IEI004586 Protein protein interactors of human gene FASTK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FASTK (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX020400 GO:0030238 biological process male sex determination The specification of male sex of an individual organism. (more detail) 15 NA Homo sapiens

GOA TAX028114 GO:0060749 biological process mammary gland alveolus development The progression of the mammary gland alveolus over time, from its formation to its mature state. The (more detail) 15 NA Homo sapiens

GOA IEI008942 Protein protein interactors of human gene NOP10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOP10 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI007470 Protein protein interactors of human gene LSM14A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSM14A (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI001554 Protein protein interactors of human gene C1QB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C1QB (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D TAX022710 GO:0035050 biological process embryonic heart tube development The process whose specific outcome is the progression of the embryonic heart tube over time, from it (more detail) 15 NA Homo sapiens

GOA IEI008323 Protein protein interactors of human gene MTF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTF2 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D TAX028281 GO:0061053 biological process somite development The progression of a somite from its initial formation to the mature structure. Somites are mesoderm (more detail) 15 NA Homo sapiens

GOA TAX029584 GO:0071637 biological process regulation of monocyte chemotactic protein 1 production Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic prot (more detail) 15 NA Homo sapiens

GOA TAX027570 GO:0055089 biological process fatty acid homeostasis Any process involved in the maintenance of an internal steady state of fatty acid within an organism (more detail) 15 NA Homo sapiens

GOA IEI013634 Protein protein interactors of human gene TGFBR3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TGFBR3 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI007002 Protein protein interactors of human gene KRI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KRI1 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D TAX026182 GO:0048485 biological process sympathetic nervous system development The process whose specific outcome is the progression of the sympathetic nervous system over time, f (more detail) 15 NA Homo sapiens

GOA IEI012939 Protein protein interactors of human gene SPTBN4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPTBN4 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI001073 Protein protein interactors of human gene ATP2B2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP2B2 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D TAX033662 GO:1904874 biological process positive regulation of telomerase RNA localization to Cajal body Any process that activates or increases the frequency, rate or extent of telomerase RNA localization (more detail) 15 NA Homo sapiens

GOA IEI003316 Protein protein interactors of human gene DBF4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DBF4B (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI010241 Protein protein interactors of human gene POLRMT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLRMT (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D TAX027983 GO:0060547 biological process negative regulation of necrotic cell death Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death (more detail) 15 NA Homo sapiens

GOA IEI015072 Protein protein interactors of human gene WNT3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WNT3A (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI010276 Protein protein interactors of human gene POU2AF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POU2AF1 (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D TAX027734 GO:0060192 biological process negative regulation of lipase activity Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lip (more detail) 15 NA Homo sapiens

GOA TAX024413 GO:0043518 biological process negative regulation of DNA damage response, signal transduction by p53 class mediator Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of process (more detail) 15 NA Homo sapiens

GOA IEI006813 Protein protein interactors of human gene KIDINS220 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIDINS220 (SwissProt (more detail) 15 17535438 Homo sapiens

I2D IEI000993 Protein protein interactors of human gene ASPM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASPM (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI001312 Protein protein interactors of human gene BEND3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BEND3 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D TAX021746 GO:0032740 biological process positive regulation of interleukin 17 production Any process that activates or increases the frequency, rate, or extent of production of any member o (more detail) 15 NA Homo sapiens

GOA TAX022982 GO:0035613 molecular function RNA stem loop binding Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is (more detail) 15 NA Homo sapiens

GOA TAX022880 GO:0035458 biological process cellular response to interferon beta Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 15 NA Homo sapiens

GOA TAX026216 GO:0048546 biological process digestive tract morphogenesis The process in which the anatomical structures of the digestive tract are generated and organized. T (more detail) 15 NA Homo sapiens

GOA TAX035079 GO:2001185 biological process regulation of CD8 positive, alpha beta T cell activation Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activati (more detail) 15 NA Homo sapiens

GOA TAX032407 GO:1902187 biological process negative regulation of viral release from host cell Any process that stops, prevents or reduces the frequency, rate or extent of viral release from host (more detail) 15 NA Homo sapiens

GOA IEI003602 Protein protein interactors of human gene DLX4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLX4 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D TAX034966 GO:2000846 biological process regulation of corticosteroid hormone secretion Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion. (more detail) 15 NA Homo sapiens

GOA IEI015852 Protein protein interactors of human gene ZSCAN32 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZSCAN32 (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D IEI003117 Protein protein interactors of human gene CTLA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTLA4 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D TAX027980 GO:0060544 biological process regulation of necroptotic process Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell d (more detail) 15 NA Homo sapiens

GOA TAX023554 GO:0038201 cellular component TOR complex A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling c (more detail) 15 NA Homo sapiens

GOA TAX023118 GO:0035855 biological process megakaryocyte development The process whose specific outcome is the progression of a megakaryocyte cell over time, from its fo (more detail) 15 NA Homo sapiens

GOA IEI005282 Protein protein interactors of human gene GMEB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GMEB1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D WIG001189 Genes involved in SHC1 events in EGFR signaling (more detail) 15 NA Homo sapiens

MSigDB TAX017924 GO:0010463 biological process mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell popula (more detail) 15 NA Homo sapiens

GOA MOX012423 Genes associated with Computational Drug Signature Doramapimod Genes associated with Computational Drug Signature Doramapimod, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB WIG000342 Hypoxia Inducible Factor in the Cardiovascular System Hypoxia (or low O2 levels) affects various pathologies. First, tissue ischemia, a variation in O2 te (more detail) 15 NA Homo sapiens

MSigDB WIG001225 Genes involved in Signalling to p38 via RIT and RIN (more detail) 15 NA Homo sapiens

MSigDB MOX004004 Genes associated with Computational Drug Signature DIOSGENIN Genes associated with Computational Drug Signature DIOSGENIN, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX000069 Genes associated with Computational Drug Signature Cinobufagin Genes associated with Computational Drug Signature Cinobufagin, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB MEX001495 Genes associated with Kinase Inhibitor H 89 DIHYDROCHLORIDE Genes associated with Kinase Inhibitor H-89 DIHYDROCHLORIDE, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MEX001146 Genes associated with Approved Drug cytomel Genes associated with Approved Drug cytomel, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB MOX003332 Genes associated with Computational Drug Signature GW0742 Genes associated with Computational Drug Signature GW0742, curated by the Drug Signature Database (D (more detail) 15 25990557 Homo sapiens

DSigDB MOX014298 Genes associated with Computational Drug Signature oxindole i Genes associated with Computational Drug Signature oxindole i, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens

DSigDB WIG000202 Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. na (more detail) 15 NA Homo sapiens

MSigDB WIG001050 Genes involved in Oxygen dependent Proline Hydroxylation of Hypoxia inducible Factor Alpha (more detail) 15 NA Homo sapiens

MSigDB MOX004976 Genes associated with Computational Drug Signature Dimaprit Genes associated with Computational Drug Signature Dimaprit, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX002651 Genes associated with Computational Drug Signature Oroxylin A Genes associated with Computational Drug Signature Oroxylin A, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens

DSigDB TAX014459 GO:0002830 biological process positive regulation of type 2 immune response Any process that activates or increases the frequency, rate, or extent of a type 2 immune response. (more detail) 15 NA Homo sapiens

GOA TAX015636 GO:0005161 molecular function platelet derived growth factor receptor binding Interacting selectively and non-covalently with the platelet-derived growth factor receptor. (more detail) 15 NA Homo sapiens

GOA MOX007581 Genes associated with Computational Drug Signature Cgs 15943 Genes associated with Computational Drug Signature Cgs 15943, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX012826 Genes associated with Computational Drug Signature gemfibrozil Genes associated with Computational Drug Signature gemfibrozil, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB FOX000725 Genes in the cancer module 432 (more detail) 15 NA Homo sapiens

MSigDB TAX000220 Genes annotated by the GO term GO:0051318. Progression through G1 phase, one of two 'gap' phases in the cell cycle; G1 is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis. (more detail) 15 NA Homo sapiens

MSigDB MEX001966 Genes associated with Kinase Inhibitor CHEMBL1950303 Genes associated with Kinase Inhibitor CHEMBL1950303, curated by the Drug Signature Database (DSigDB (more detail) 15 25990557 Homo sapiens

DSigDB MEX002345 Genes associated with Kinase Inhibitor bisindolylmaleimide i Genes associated with Kinase Inhibitor bisindolylmaleimide i, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX000574 Genes associated with Computational Drug Signature MELAMINE Genes associated with Computational Drug Signature MELAMINE, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MEX001548 Genes associated with Kinase Inhibitor su6656 Genes associated with Kinase Inhibitor su6656, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB MOX003445 Genes associated with Computational Drug Signature pd 168393 Genes associated with Computational Drug Signature pd 168393, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB WAG001240 ctcf: first multivalent nuclear factor CTCF is central to sigling pathways in immature B cells elicited by cross-linking the Ig BCR and sti (more detail) 15 NA Homo sapiens

BioCarta FEX001389 Leukemia Chiaretti05 16genes Table 4. Kinase genes with high-level gene expression in samples without known molecular rearrangeme (more detail) 15 16243790 Homo sapiens

GeneSigDB WIG001131 Genes involved in Regulation of AMPK activity via LKB1 (more detail) 15 NA Homo sapiens

MSigDB WIG001986 Hedgehog Signaling Pathway Hedgehog Signaling Pathway (more detail) 15 NA Homo sapiens

WikiPathway MOX014862 Genes associated with Computational Drug Signature Rocaglamide Genes associated with Computational Drug Signature Rocaglamide, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB WAG000848 tgf beta signaling pathway TGF-beta regulates growth and proliferation of cells, blocking growth of many cell types. The TGF-be (more detail) 15 NA Homo sapiens

BioCarta WIG000253 Protein Kinase A at the Centrosome Protein kinase A regulatory subunit RIIalpha (PKA-RIIa) is tightly bound to centrosomal structures d (more detail) 15 NA Homo sapiens

MSigDB WIG000779 Genes involved in Cyclin A/B1 associated events during G2/M transition (more detail) 15 NA Homo sapiens

MSigDB MOX001709 Genes associated with Computational Drug Signature Tetrachlorodian Genes associated with Computational Drug Signature Tetrachlorodian, curated by the Drug Signature Da (more detail) 15 25990557 Homo sapiens

DSigDB MOX000863 Genes associated with Computational Drug Signature Carnosic acid Genes associated with Computational Drug Signature Carnosic acid, curated by the Drug Signature Data (more detail) 15 25990557 Homo sapiens

DSigDB MOX002792 Genes associated with Computational Drug Signature CHEMBL55802 Genes associated with Computational Drug Signature CHEMBL55802, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB IEI013579 Protein protein interactors of human gene TET3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TET3 (SwissProt ID=O (more detail) 21 17535438 Homo sapiens

I2D IEI005749 Protein protein interactors of human gene HDAC10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDAC10 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI006127 Protein protein interactors of human gene HYPK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HYPK (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI005023 Protein protein interactors of human gene GAK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GAK (SwissProt ID=O1 (more detail) 21 17535438 Homo sapiens

I2D TAX025111 GO:0045453 biological process bone resorption The process in which specialized cells known as osteoclasts degrade the organic and inorganic portio (more detail) 21 NA Homo sapiens

GOA IEI009046 Protein protein interactors of human gene NRBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NRBP1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D TAX025833 GO:0046961 molecular function proton transporting ATPase activity, rotational mechanism Enables the transfer of protons from one side of a membrane to the other according to the reaction: (more detail) 21 NA Homo sapiens

GOA IEI007215 Protein protein interactors of human gene LENG8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LENG8 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI003126 Protein protein interactors of human gene CTNND2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTNND2 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI007605 Protein protein interactors of human gene MAGI2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAGI2 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI005277 Protein protein interactors of human gene GLYR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLYR1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI001825 Protein protein interactors of human gene CASP8AP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASP8AP2 (SwissProt (more detail) 21 17535438 Homo sapiens

I2D IEI009025 Protein protein interactors of human gene NR1I3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR1I3 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI003591 Protein protein interactors of human gene DLGAP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLGAP3 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D TAX033602 GO:1904752 biological process regulation of vascular associated smooth muscle cell migration Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell m (more detail) 21 NA Homo sapiens

GOA IEI015821 Protein protein interactors of human gene ZNHIT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNHIT1 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI002586 Protein protein interactors of human gene CKS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CKS2 (SwissProt ID=P (more detail) 21 17535438 Homo sapiens

I2D IEI014558 Protein protein interactors of human gene UBASH3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBASH3A (SwissProt I (more detail) 21 17535438 Homo sapiens

I2D TAX024847 GO:0044788 biological process modulation by host of viral process A process in which a host organism modulates the frequency, rate or extent of any of a process being (more detail) 21 NA Homo sapiens

GOA IEI007135 Protein protein interactors of human gene LAMTOR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LAMTOR2 (SwissProt I (more detail) 21 17535438 Homo sapiens

I2D IEI013013 Protein protein interactors of human gene SSBP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SSBP3 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI009379 Protein protein interactors of human gene OTUD7B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OTUD7B (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D TAX031468 GO:0101031 cellular component chaperone complex A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or a (more detail) 21 NA Homo sapiens

GOA IEI000454 Protein protein interactors of human gene AKT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKT3 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI004679 Protein protein interactors of human gene FCGR2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FCGR2B (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI006297 Protein protein interactors of human gene IL13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL13 (SwissProt ID=P (more detail) 21 17535438 Homo sapiens

I2D FEX001761 Liver Chan09 22genes Table 2. Partial list of cancer-implicated genes aberrantly regulated by the HCCTR mutants (more detail) 21 19749797 Homo sapiens

GeneSigDB MOX004359 Genes associated with Computational Drug Signature metoprolol Genes associated with Computational Drug Signature metoprolol, curated by the Drug Signature Databas (more detail) 21 25990557 Homo sapiens

DSigDB MEX000659 Genes associated with Approved Drug paroxetine hydrochloride Genes associated with Approved Drug paroxetine hydrochloride, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens

DSigDB WIG000075 Signaling events mediated by the Hedgehog family (more detail) 21 NA Homo sapiens

MSigDB MAX002839 Genes modulated in HeLa cells (cervical carcinoma) by TNF [GeneID=7124] not via NFKB pathway. Tumor necrosis factor (TNF) is a pro-inflammatory cytokine that controls expression of inflammatory (more detail) 21 NA Homo sapiens

MSigDB MOX012587 Genes associated with Computational Drug Signature ethinyl estradiol Genes associated with Computational Drug Signature ethinyl estradiol, curated by the Drug Signature (more detail) 21 25990557 Homo sapiens

DSigDB MOX006598 Genes associated with Computational Drug Signature acetate Genes associated with Computational Drug Signature acetate, curated by the Drug Signature Database ( (more detail) 21 25990557 Homo sapiens

DSigDB MOX002203 Genes associated with Computational Drug Signature Polydatin Genes associated with Computational Drug Signature Polydatin, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens

DSigDB TAX000184 Genes annotated by the GO term GO:0006302. The repair of double strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. (more detail) 21 NA Homo sapiens

MSigDB WIG001716 TWEAK Pathway TWEAK Pathway (more detail) 21 NA Homo sapiens

Protein Lounge TAX000337 Genes annotated by the GO term GO:0007498. The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. (more detail) 21 NA Homo sapiens

MSigDB MAX000623 Genes up regulated in HT 29 cells (colon cancer) by the combination of trichostatin A (TSA) and sodium butyrate [PubChem=5562;5222465]. A wealth of evidence correlates the chemopreventive activity of a fiber-rich diet with the productio (more detail) 21 NA Homo sapiens

MSigDB GEX000507 coronary heart disease coronary heart disease associated genes. PAGER constructed this gene set by grouping all genes which (more detail) 21 NA Homo sapiens

GAD WAG000037 Signaling events mediated by the Hedgehog family (more detail) 21 NA Homo sapiens

NCI-Nature Curated MOX005081 Genes associated with Computational Drug Signature losartan Genes associated with Computational Drug Signature losartan, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens

DSigDB MOX000235 Genes associated with Computational Drug Signature CHLOROTHALONIL Genes associated with Computational Drug Signature CHLOROTHALONIL, curated by the Drug Signature Dat (more detail) 21 25990557 Homo sapiens

DSigDB MOX003712 Genes associated with Computational Drug Signature Azinphos methyl Genes associated with Computational Drug Signature Azinphos-methyl, curated by the Drug Signature Da (more detail) 21 25990557 Homo sapiens

DSigDB MEX002120 Genes associated with Kinase Inhibitor GW559768X Genes associated with Kinase Inhibitor GW559768X, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens

DSigDB TAX000527 Genes annotated by the GO term GO:0050870. Any process that activates or increases the frequency, rate or extent of T cell activation. (more detail) 21 NA Homo sapiens

MSigDB TAX001275 Genes annotated by the GO term GO:0008080. Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. (more detail) 21 NA Homo sapiens

MSigDB TAX000196 Genes annotated by the GO term GO:0007173. The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands. (more detail) 21 NA Homo sapiens

MSigDB MOX015660 Genes associated with Computational Drug Signature TTNPB Genes associated with Computational Drug Signature TTNPB, curated by the Drug Signature Database (DS (more detail) 21 25990557 Homo sapiens

DSigDB FEX000823 Colon DellaRagione01 21genes Table 1. Human genes induced by BuA and TSA (more detail) 21 11423116 Homo sapiens

GeneSigDB WIG000377 Role of Mitochondria in Apoptotic Signaling Mitochondria participate in apoptotic signaling pathways through the release of mitochondrial protei (more detail) 21 NA Homo sapiens

MSigDB TAX014023 GO:0002042 biological process cell migration involved in sprouting angiogenesis The orderly movement of endothelial cells into the extracellular matrix in order to form new blood v (more detail) 21 NA Homo sapiens

GOA IEI009453 Protein protein interactors of human gene PAIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAIP1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI008041 Protein protein interactors of human gene MLX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MLX (SwissProt ID=Q9 (more detail) 17 17535438 Homo sapiens

I2D IEI014175 Protein protein interactors of human gene TRAM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRAM1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI014818 Protein protein interactors of human gene UTP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UTP4 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D IEI004820 Protein protein interactors of human gene FLT4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FLT4 (SwissProt ID=P (more detail) 17 17535438 Homo sapiens

I2D IEI008966 Protein protein interactors of human gene NOXA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOXA1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI000115 Protein protein interactors of human gene ACAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACAP1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI006990 Protein protein interactors of human gene KPNA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KPNA5 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI000431 Protein protein interactors of human gene AKAP6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKAP6 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI001432 Protein protein interactors of human gene BRF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRF1 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D IEI008489 Protein protein interactors of human gene MYOCD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYOCD (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI010099 Protein protein interactors of human gene PLK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLK3 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D IEI010346 Protein protein interactors of human gene PPP1R14A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R14A (SwissProt (more detail) 17 17535438 Homo sapiens

I2D IEI006020 Protein protein interactors of human gene HRG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HRG (SwissProt ID=P0 (more detail) 17 17535438 Homo sapiens

I2D TAX023503 GO:0038111 biological process interleukin 7 mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-7 to a receptor on the surface (more detail) 17 NA Homo sapiens

GOA TAX032551 GO:1902547 biological process regulation of cellular response to vascular endothelial growth factor stimulus Any process that modulates the frequency, rate or extent of cellular response to vascular endothelia (more detail) 17 NA Homo sapiens

GOA IEI003448 Protein protein interactors of human gene DEF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DEF6 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D IEI011013 Protein protein interactors of human gene RASA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RASA4 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI004926 Protein protein interactors of human gene FST from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FST (SwissProt ID=P1 (more detail) 17 17535438 Homo sapiens

I2D IEI014442 Protein protein interactors of human gene TTI2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTI2 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D TAX022751 GO:0035173 molecular function histone kinase activity Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-so (more detail) 17 NA Homo sapiens

GOA TAX023476 GO:0038061 biological process NIK/NF kappaB signaling The process in which a signal is passed on to downstream components within the cell through the NIK- (more detail) 17 NA Homo sapiens

GOA IEI008793 Protein protein interactors of human gene NFIL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFIL3 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI010572 Protein protein interactors of human gene PRRC2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRRC2B (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D TAX021730 GO:0032717 biological process negative regulation of interleukin 8 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 product (more detail) 17 NA Homo sapiens

GOA IEI008920 Protein protein interactors of human gene NOC3L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOC3L (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI010593 Protein protein interactors of human gene PRTN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRTN3 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D WEX000023 EGFR Signaling The genes related to egfr signaling (signaling pathways) in tumor using next-generation sequencer (N (more detail) 17 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI012786 Protein protein interactors of human gene SOX6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOX6 (SwissProt ID=P (more detail) 17 17535438 Homo sapiens

I2D IEI000097 Protein protein interactors of human gene ABRAXAS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABRAXAS2 (SwissProt (more detail) 17 17535438 Homo sapiens

I2D IEI010068 Protein protein interactors of human gene PLEKHB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLEKHB1 (SwissProt I (more detail) 17 17535438 Homo sapiens

I2D WAG001456 growth hormone signaling pathway Growth hormone plays a major role in regulating growth during childhood and adolescence and also reg (more detail) 17 NA Homo sapiens

BioCarta WIG002007 ACE Inhibitor Pathway ACE Inhibitor Pathway (more detail) 17 NA Homo sapiens

WikiPathway WIG001455 Complement Pathway Complement Pathway (more detail) 17 NA Homo sapiens

Protein Lounge MEX001683 Genes associated with Kinase Inhibitor Kinome 452 Genes associated with Kinase Inhibitor Kinome_452, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB MOX000752 Genes associated with Computational Drug Signature estradiol valerate Genes associated with Computational Drug Signature estradiol valerate, curated by the Drug Signature (more detail) 17 25990557 Homo sapiens

DSigDB TAX014047 GO:0002076 biological process osteoblast development The process whose specific outcome is the progression of an osteoblast over time, from its formation (more detail) 17 NA Homo sapiens

GOA MAX003268 Genes in cluster 4: immediate down regulation in HFW cells (fibroblast) by sodium arsenite [PubChem=26435]. Arsenic compounds are widely distributed and arsenic ingestion is associated with many human disease (more detail) 17 NA Homo sapiens

MSigDB TAX000981 Genes annotated by the GO term GO:0055029. A protein complex, located in the nucleus, that possesses DNA directed RNA polymerase activity. (more detail) 17 NA Homo sapiens

MSigDB MEX001914 Genes associated with Kinase Inhibitor 929095 18 1 Genes associated with Kinase Inhibitor 929095-18-1, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB MOX003149 Genes associated with Computational Drug Signature Temsirolimus Genes associated with Computational Drug Signature Temsirolimus, curated by the Drug Signature Datab (more detail) 17 25990557 Homo sapiens

DSigDB TAX018148 GO:0010832 biological process negative regulation of myotube differentiation Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differe (more detail) 17 NA Homo sapiens

GOA WIG001193 Genes involved in SHC related events (more detail) 17 NA Homo sapiens

MSigDB TAX001027 Genes annotated by the GO term GO:0030880. Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits. (more detail) 17 NA Homo sapiens

MSigDB WIG001458 Activation of NF KappaB by PKR Activation of NF-KappaB by PKR (more detail) 17 NA Homo sapiens

Protein Lounge MOX006928 Genes associated with Computational Drug Signature alsterpaullone Genes associated with Computational Drug Signature alsterpaullone, curated by the Drug Signature Dat (more detail) 17 25990557 Homo sapiens

DSigDB WAG001280 S1P3 pathway (more detail) 17 NA Homo sapiens

NCI-Nature Curated GEX168106 Simon et al., 2012 04 01, Genes and Development, A key role for EZH2 and associated genes in mouse and human adult T cell acute leukemia T-cell leukemia (T-ALL) Mutation type(Somatic mutation) (more detail) 17 22431509 Homo sapiens

NGS Catalog WAG000414 tnfr1 signaling pathway TNFR1 (a.k.a. p55, CD120a) is the receptor for TNF(alpha) and also will bind TNF(beta). Upon binding (more detail) 17 NA Homo sapiens

BioCarta WAG001238 role of nicotinic acetylcholine receptors in the regulation of apoptosis Nicotinic acetylcholine receptors are essential for neuromuscular sigling and are also expressed in (more detail) 17 NA Homo sapiens

BioCarta WIG001344 Bisphosphonate Pathway, Pharmacodynamics Representation of genes involved in bisphosphonates' effects in osteoclasts. (more detail) 17 NA Homo sapiens

PharmGKB MEX001909 Genes associated with Kinase Inhibitor gw8510 Genes associated with Kinase Inhibitor gw8510, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB MOX002790 Genes associated with Computational Drug Signature bisindolylmaleimide iv Genes associated with Computational Drug Signature bisindolylmaleimide iv, curated by the Drug Signa (more detail) 17 25990557 Homo sapiens

DSigDB MOX013108 Genes associated with Computational Drug Signature Imatinib Genes associated with Computational Drug Signature Imatinib, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens

DSigDB TAX014390 GO:0002710 biological process negative regulation of T cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immun (more detail) 17 NA Homo sapiens

GOA FEX003018 StemCell Singer07 25genes Table 1a. Overexpressed genes in well-differentiated liposarcoma compared with normal fat (more detail) 17 17638873 Homo sapiens

GeneSigDB FEX003009 StemCell Tsai07 19genes Table 3. TGF-?/SMAD-associated genes induced by either SD or MF exposure in MCF7 SF539 or DU145 (more detail) 17 17440099 Homo sapiens

GeneSigDB TAX000881 Genes annotated by the GO term GO:0000428. A protein complex that possesses DNA directed RNA polymerase activity. (more detail) 17 NA Homo sapiens

MSigDB TAX023176 GO:0035967 biological process cellular response to topologically incorrect protein Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 19 NA Homo sapiens

GOA TAX020941 GO:0031342 biological process negative regulation of cell killing Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing. (more detail) 19 NA Homo sapiens

GOA IEI001005 Protein protein interactors of human gene ATAD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATAD2 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI013629 Protein protein interactors of human gene TGFB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TGFB2 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI011536 Protein protein interactors of human gene RPL37 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL37 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX028812 GO:0070233 biological process negative regulation of T cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apopto (more detail) 19 NA Homo sapiens

GOA IEI008523 Protein protein interactors of human gene NAA20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NAA20 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI000394 Protein protein interactors of human gene AHSG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AHSG (SwissProt ID=P (more detail) 19 17535438 Homo sapiens

I2D IEI005317 Protein protein interactors of human gene GNG12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GNG12 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX022337 GO:0034143 biological process regulation of toll like receptor 4 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway. (more detail) 19 NA Homo sapiens

GOA TAX032360 GO:1902074 biological process response to salt Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 19 NA Homo sapiens

GOA IEI008784 Protein protein interactors of human gene NFATC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFATC4 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI012739 Protein protein interactors of human gene SNX8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNX8 (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D IEI001075 Protein protein interactors of human gene ATP2B4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP2B4 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI010960 Protein protein interactors of human gene RAI14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAI14 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI015792 Protein protein interactors of human gene ZNF827 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF827 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D TAX029233 GO:0070987 biological process error free translesion synthesis The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after repl (more detail) 19 NA Homo sapiens

GOA MEX002011 Genes associated with Kinase Inhibitor SB 203580 Genes associated with Kinase Inhibitor SB 203580, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB MOX001820 Genes associated with Computational Drug Signature benazepril Genes associated with Computational Drug Signature benazepril, curated by the Drug Signature Databas (more detail) 19 25990557 Homo sapiens

DSigDB MOX005044 Genes associated with Computational Drug Signature 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE Genes associated with Computational Drug Signature 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE, cu (more detail) 19 25990557 Homo sapiens

DSigDB WAG001471 signaling pathway from g protein families G-aS-coupled receptors stimulate adenylyl cyclase (AC), which synthesizes cAMP from ATP. In contras (more detail) 19 NA Homo sapiens

BioCarta WIG000293 Complement Pathway The complement pathway consists of a series of over thirty proteins in plasma that are part of the i (more detail) 19 NA Homo sapiens

MSigDB MOX002092 Genes associated with Computational Drug Signature Manumycin A Genes associated with Computational Drug Signature Manumycin A, curated by the Drug Signature Databa (more detail) 19 25990557 Homo sapiens

DSigDB MOX016137 Genes associated with Computational Drug Signature 5 Methylcytosine Genes associated with Computational Drug Signature 5-Methylcytosine, curated by the Drug Signature D (more detail) 19 25990557 Homo sapiens

DSigDB FOX000587 Genes in the cancer module 262 (more detail) 19 NA Homo sapiens

MSigDB MAX001134 Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive B lineage ALL; here genes up regulated in the drug resistant samples. Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percen (more detail) 19 NA Homo sapiens

MSigDB WIG000375 Role of MEF2D in T cell Apoptosis Mef2 pathway. (more detail) 19 NA Homo sapiens

MSigDB MAX000513 Substrates of PRKDC [GeneID=5591]. Double-strand breaks (DSBs) arise endogenously during normal cellular processes and exogenously by g (more detail) 19 NA Homo sapiens

MSigDB WIG001996 Hypertrophy Model Hypertrophy Model (more detail) 19 NA Homo sapiens

WikiPathway PEX001175 WW: WW domain The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich pept (more detail) 19 NA Homo sapiens

Pfam GEX167149 LDL cholesterol Genetic variants influencing circulating lipid levels and risk of coronary artery disease. (more detail) 19 20864672 Homo sapiens

GWAS Catalog MOX003921 Genes associated with Computational Drug Signature p,p' DDD Genes associated with Computational Drug Signature p,p'-DDD, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB MOX001383 Genes associated with Computational Drug Signature 4 Aminodiphenylamine Genes associated with Computational Drug Signature 4-Aminodiphenylamine, curated by the Drug Signatu (more detail) 19 25990557 Homo sapiens

DSigDB MAX001135 Genes distinguishing vincristine [PubChem=5978] resistant and sensitive ALL (B and T lineage ALL); here genes down regulated in the drug resistant samples. Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percen (more detail) 19 NA Homo sapiens

MSigDB WIG000273 Effects of calcineurin in Keratinocyte Differentiation The differentiation of keratinocytes constantly replenishes the upper layers of human skin we lose e (more detail) 19 NA Homo sapiens

MSigDB MOX017528 Genes associated with Computational Drug Signature Picryl sulfonic acid Genes associated with Computational Drug Signature Picryl sulfonic acid, curated by the Drug Signatu (more detail) 19 25990557 Homo sapiens

DSigDB MOX003132 Genes associated with Computational Drug Signature alsterpaullone Genes associated with Computational Drug Signature alsterpaullone, curated by the Drug Signature Dat (more detail) 19 25990557 Homo sapiens

DSigDB MOX015899 Genes associated with Computational Drug Signature wortmannin Genes associated with Computational Drug Signature wortmannin, curated by the Drug Signature Databas (more detail) 19 25990557 Homo sapiens

DSigDB MEX000678 Genes associated with Approved Drug mefloquine hydrochloride Genes associated with Approved Drug mefloquine hydrochloride, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB FEX000156 Brain Hui04 33genes Table 1 SERM-responsible genes (more detail) 19 15604281 Homo sapiens

GeneSigDB MOX015246 Genes associated with Computational Drug Signature Sunitinib Genes associated with Computational Drug Signature Sunitinib, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB MEX000291 Genes associated with Approved Drug pyrimethamine Genes associated with Approved Drug pyrimethamine, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB WIG000654 Genes involved in Activated AMPK stimulates fatty acid oxidation in muscle (more detail) 19 NA Homo sapiens

MSigDB MEX000368 Genes associated with Approved Drug spironolactone Genes associated with Approved Drug spironolactone, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB IEI008506 Protein protein interactors of human gene MYT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYT1 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D TAX022329 GO:0034135 biological process regulation of toll like receptor 2 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway. (more detail) 10 NA Homo sapiens

GOA TAX027531 GO:0055015 biological process ventricular cardiac muscle cell development The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time (more detail) 10 NA Homo sapiens

GOA TAX026394 GO:0048935 biological process peripheral nervous system neuron development The process whose specific outcome is the progression of a neuron whose cell body is located in the (more detail) 10 NA Homo sapiens

GOA IEI014817 Protein protein interactors of human gene UTP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UTP3 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D TAX021451 GO:0032306 biological process regulation of prostaglandin secretion Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin (more detail) 10 NA Homo sapiens

GOA TAX029153 GO:0070862 biological process negative regulation of protein exit from endoplasmic reticulum Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement (more detail) 10 NA Homo sapiens

GOA TAX024077 GO:0042975 molecular function peroxisome proliferator activated receptor binding Interacting selectively and non-covalently with any of the peroxisome proliferator activated recepto (more detail) 10 NA Homo sapiens

GOA TAX027223 GO:0051864 molecular function histone demethylase activity (H3 K36 specific) Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = (more detail) 10 NA Homo sapiens

GOA TAX026138 GO:0048304 biological process positive regulation of isotype switching to IgG isotypes Any process that activates or increases the frequency, rate or extent of isotype switching to IgG is (more detail) 10 NA Homo sapiens

GOA TAX032128 GO:1901407 biological process regulation of phosphorylation of RNA polymerase II C terminal domain Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-t (more detail) 10 NA Homo sapiens

GOA TAX033394 GO:1904338 biological process regulation of dopaminergic neuron differentiation Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation. (more detail) 10 NA Homo sapiens

GOA TAX033050 GO:1903624 biological process regulation of DNA catabolic process Any process that modulates the frequency, rate or extent of DNA catabolic process. (more detail) 10 NA Homo sapiens

GOA IEI009664 Protein protein interactors of human gene PDE3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDE3B (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI010369 Protein protein interactors of human gene PPP1R3D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R3D (SwissProt I (more detail) 10 17535438 Homo sapiens

I2D IEI012057 Protein protein interactors of human gene SESN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SESN2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D TAX017306 GO:0008494 molecular function translation activator activity Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of (more detail) 10 NA Homo sapiens

GOA TAX030396 GO:0090193 biological process positive regulation of glomerulus development Any process that increases the rate, frequency or extent of glomerulus development, the progression (more detail) 10 NA Homo sapiens

GOA TAX025074 GO:0045346 biological process regulation of MHC class II biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 10 NA Homo sapiens

GOA TAX024272 GO:0043276 biological process anoikis Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of t (more detail) 10 NA Homo sapiens

GOA TAX032082 GO:1901298 biological process regulation of hydrogen peroxide mediated programmed cell death Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed ce (more detail) 10 NA Homo sapiens

GOA TAX034131 GO:1990001 biological process inhibition of cysteine type endopeptidase activity involved in apoptotic process Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an a (more detail) 10 NA Homo sapiens

GOA TAX032758 GO:1903025 biological process regulation of RNA polymerase II regulatory region sequence specific DNA binding Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequ (more detail) 10 NA Homo sapiens

GOA IEI003886 Protein protein interactors of human gene DZIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DZIP1 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI011992 Protein protein interactors of human gene SENP6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SENP6 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI005911 Protein protein interactors of human gene HMGN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMGN3 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D TAX021318 GO:0032070 biological process regulation of deoxyribonuclease activity Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolys (more detail) 10 NA Homo sapiens

GOA TAX024415 GO:0043522 molecular function leucine zipper domain binding Interacting selectively and non-covalently with a leucine zipper domain, a protein secondary structu (more detail) 10 NA Homo sapiens

GOA TAX021613 GO:0032525 biological process somite rostral/caudal axis specification The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the m (more detail) 10 NA Homo sapiens

GOA TAX034121 GO:1905941 biological process positive regulation of gonad development Any process that activates or increases the frequency, rate or extent of gonad development. (more detail) 10 NA Homo sapiens

GOA TAX034392 GO:1990909 cellular component Wnt signalosome A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein com (more detail) 10 NA Homo sapiens

GOA TAX027834 GO:0060340 biological process positive regulation of type I interferon mediated signaling pathway Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling p (more detail) 10 NA Homo sapiens

GOA TAX032698 GO:1902916 biological process positive regulation of protein polyubiquitination Any process that activates or increases the frequency, rate or extent of protein polyubiquitination. (more detail) 10 NA Homo sapiens

GOA IEI009457 Protein protein interactors of human gene PAK1IP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAK1IP1 (SwissProt I (more detail) 10 17535438 Homo sapiens

I2D TAX022000 GO:0033148 biological process positive regulation of intracellular estrogen receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the activity of an intracel (more detail) 10 NA Homo sapiens

GOA TAX023555 GO:0038202 biological process TORC1 signaling A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex (more detail) 10 NA Homo sapiens

GOA TAX018060 GO:0010713 biological process negative regulation of collagen metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 10 NA Homo sapiens

GOA TAX024686 GO:0044320 biological process cellular response to leptin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 10 NA Homo sapiens

GOA TAX021276 GO:0032000 biological process positive regulation of fatty acid beta oxidation Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation. (more detail) 10 NA Homo sapiens

GOA TAX027064 GO:0051567 biological process histone H3 K9 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of t (more detail) 10 NA Homo sapiens

GOA TAX033652 GO:1904851 biological process positive regulation of establishment of protein localization to telomere Any process that activates or increases the frequency, rate or extent of establishment of protein lo (more detail) 10 NA Homo sapiens

GOA TAX032269 GO:1901836 biological process regulation of transcription of nucleolar large rRNA by RNA polymerase I Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA medi (more detail) 10 NA Homo sapiens

GOA IEI004862 Protein protein interactors of human gene FOXC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXC2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI006394 Protein protein interactors of human gene INHBB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INHBB (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D TAX021473 GO:0032353 biological process negative regulation of hormone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 10 NA Homo sapiens

GOA TAX029840 GO:0072111 biological process cell proliferation involved in kidney development The multiplication or reproduction of cells, resulting in the expansion of the population in the kid (more detail) 10 NA Homo sapiens

GOA TAX028990 GO:0070544 biological process histone H3 K36 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the hi (more detail) 10 NA Homo sapiens

GOA TAX020899 GO:0031284 biological process positive regulation of guanylate cyclase activity Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity. (more detail) 10 NA Homo sapiens

GOA TAX025178 GO:0045625 biological process regulation of T helper 1 cell differentiation Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation. (more detail) 10 NA Homo sapiens

GOA TAX025250 GO:0045741 biological process positive regulation of epidermal growth factor activated receptor activity Any process that activates or increases the frequency, rate or extent of EGF-activated receptor acti (more detail) 10 NA Homo sapiens

GOA TAX033710 GO:1904953 biological process Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation Any Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation. (more detail) 10 NA Homo sapiens

GOA TAX031782 GO:1900044 biological process regulation of protein K63 linked ubiquitination Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination. (more detail) 10 NA Homo sapiens

GOA TAX035032 GO:2001054 biological process negative regulation of mesenchymal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apopto (more detail) 10 NA Homo sapiens

GOA TAX031882 GO:1900221 biological process regulation of amyloid beta clearance Any process that modulates the frequency, rate or extent of amyloid-beta clearance. (more detail) 10 NA Homo sapiens

GOA TAX034824 GO:2000628 biological process regulation of miRNA metabolic process Any process that modulates the frequency, rate or extent of miRNA metabolic process. (more detail) 10 NA Homo sapiens

GOA IEI002835 Protein protein interactors of human gene COMMD6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD6 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI010994 Protein protein interactors of human gene RAP2C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAP2C (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D TAX025790 GO:0046886 biological process positive regulation of hormone biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 10 NA Homo sapiens

GOA TAX021065 GO:0031588 cellular component nucleotide activated protein kinase complex A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be (more detail) 10 NA Homo sapiens

GOA TAX033238 GO:1903978 biological process regulation of microglial cell activation Any process that modulates the frequency, rate or extent of microglial cell activation. (more detail) 10 NA Homo sapiens

GOA TAX034927 GO:2000786 biological process positive regulation of autophagosome assembly Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly (more detail) 10 NA Homo sapiens

GOA WEX000073 NO Signaling The genes related to no signaling (signaling pathways) in tumor, immune using next-generation sequen (more detail) 10 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI004976 Protein protein interactors of human gene FZD7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FZD7 (SwissProt ID=O (more detail) 10 17535438 Homo sapiens

I2D IEI007758 Protein protein interactors of human gene MBD3L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MBD3L1 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D TAX028324 GO:0061140 biological process lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung secreto (more detail) 10 NA Homo sapiens

GOA TAX024444 GO:0043558 biological process regulation of translational initiation in response to stress Any process that modulates the frequency, rate or extent of translation initiation, as a result of a (more detail) 10 NA Homo sapiens

GOA TAX022185 GO:0033629 biological process negative regulation of cell adhesion mediated by integrin Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediate (more detail) 10 NA Homo sapiens

GOA TAX031753 GO:0150077 biological process regulation of neuroinflammatory response Any process that modulates the frequency, rate or extent of neuroinflammatory response. (more detail) 10 NA Homo sapiens

GOA TAX031909 GO:1900272 biological process negative regulation of long term synaptic potentiation Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic pote (more detail) 10 NA Homo sapiens

GOA TAX032336 GO:1902004 biological process positive regulation of amyloid beta formation Any process that activates or increases the frequency, rate or extent of amyloid-beta formation. (more detail) 10 NA Homo sapiens

GOA IEI008788 Protein protein interactors of human gene NFE2L3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFE2L3 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI015368 Protein protein interactors of human gene ZMYM5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZMYM5 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D TAX021985 GO:0033131 biological process regulation of glucokinase activity Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of t (more detail) 10 NA Homo sapiens

GOA TAX021452 GO:0032308 biological process positive regulation of prostaglandin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a (more detail) 10 NA Homo sapiens

GOA TAX022481 GO:0034427 biological process nuclear transcribed mRNA catabolic process, exonucleolytic, 3' 5' The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occu (more detail) 10 NA Homo sapiens

GOA TAX029148 GO:0070857 biological process regulation of bile acid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 10 NA Homo sapiens

GOA TAX022245 GO:0033860 biological process regulation of NAD(P)H oxidase activity Any process that modulates the activity of the enzyme NAD(P)H oxidase. (more detail) 10 NA Homo sapiens

GOA TAX023964 GO:0042693 biological process muscle cell fate commitment The process in which the cellular identity of muscle cells is acquired and determined. (more detail) 10 NA Homo sapiens

GOA TAX020998 GO:0031442 biological process positive regulation of mRNA 3' end processing Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing. (more detail) 10 NA Homo sapiens

GOA TAX025276 GO:0045792 biological process negative regulation of cell size Any process that reduces cell size. (more detail) 10 NA Homo sapiens

GOA TAX035139 GO:2001269 biological process positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase (more detail) 10 NA Homo sapiens

GOA TAX034493 GO:2000121 biological process regulation of removal of superoxide radicals Any process that modulates the frequency, rate or extent of removal of superoxide radicals. (more detail) 10 NA Homo sapiens

GOA IEI004610 Protein protein interactors of human gene FBRS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBRS (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI013367 Protein protein interactors of human gene TAL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAL2 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI001669 Protein protein interactors of human gene C9orf72 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C9orf72 (SwissProt I (more detail) 10 17535438 Homo sapiens

I2D WIG000431 SODD/TNFR1 Signaling Pathway The tumor necrosis factor (TNF) receptor superfamily contains several members with homologous cytopl (more detail) 10 NA Homo sapiens

MSigDB MOX001178 Genes associated with Computational Drug Signature DIHEXYL PHTHALATE Genes associated with Computational Drug Signature DIHEXYL PHTHALATE, curated by the Drug Signature (more detail) 10 25990557 Homo sapiens

DSigDB TAX000286 Genes annotated by the GO term GO:0042228. The chemical reactions and pathways resulting in the formation of interleukin 8. (more detail) 10 NA Homo sapiens

MSigDB TAX001396 Genes annotated by the GO term GO:0035258. Interacting selectively with a steroid hormone receptor. (more detail) 10 NA Homo sapiens

MSigDB WIG001149 Genes involved in Regulation of Rheb GTPase activity by AMPK (more detail) 10 NA Homo sapiens

MSigDB MOX000539 Genes associated with Computational Drug Signature Tetrac Genes associated with Computational Drug Signature Tetrac, curated by the Drug Signature Database (D (more detail) 10 25990557 Homo sapiens

DSigDB MOX003045 Genes associated with Computational Drug Signature Cyprodinil Genes associated with Computational Drug Signature Cyprodinil, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB MOX002387 Genes associated with Computational Drug Signature Malvidin Genes associated with Computational Drug Signature Malvidin, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB MOX007171 Genes associated with Computational Drug Signature balanol Genes associated with Computational Drug Signature balanol, curated by the Drug Signature Database ( (more detail) 10 25990557 Homo sapiens

DSigDB MOX013460 Genes associated with Computational Drug Signature Linifanib Genes associated with Computational Drug Signature Linifanib, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB WAG000847 protein kinase a at the centrosome Protein kise A regulatory subunit RIIalpha (PKA-RIIa) is tightly bound to centrosomal structures dur (more detail) 10 NA Homo sapiens

BioCarta MEX001222 Genes associated with Kinase Inhibitor GSK 3 Inhibitor XIII Genes associated with Kinase Inhibitor GSK-3 Inhibitor XIII, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB MEX001630 Genes associated with Kinase Inhibitor Kinome 2812 Genes associated with Kinase Inhibitor Kinome_2812, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB PEX001303 Cyclin N: Cyclin, N terminal domain Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a Uracil-DNA glycosylase that is r (more detail) 10 NA Homo sapiens

Pfam WAG001466 overview of telomerase protein component gene htert transcriptional regulation Telomerase is an enzyme which replicates the termil sequences of eukaryotic chromosomes, mely the te (more detail) 10 NA Homo sapiens

BioCarta TAX001324 Genes annotated by the GO term GO:0033558. Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate. (more detail) 10 NA Homo sapiens

MSigDB WIG000670 Genes involved in Activation of the AP 1 family of transcription factors (more detail) 10 NA Homo sapiens

MSigDB WAG000028 the prc2 complex sets long term gene silencing through modification of histone tails Packaging of D into chromatin allows the cell to store its genetic information efficiently and has a (more detail) 10 NA Homo sapiens

BioCarta MOX000496 Genes associated with Computational Drug Signature Aspidin Genes associated with Computational Drug Signature Aspidin, curated by the Drug Signature Database ( (more detail) 10 25990557 Homo sapiens

DSigDB TAX014597 GO:0003149 biological process membranous septum morphogenesis The process in which the membranous septum is generated and organized. The membranous septum is the (more detail) 10 NA Homo sapiens

GOA TAX014641 GO:0003211 biological process cardiac ventricle formation The developmental process pertaining to the initial formation of a cardiac ventricle from unspecifie (more detail) 10 NA Homo sapiens

GOA MOX014386 Genes associated with Computational Drug Signature PD 0183812 Genes associated with Computational Drug Signature PD-0183812, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB TAX000284 Genes annotated by the GO term GO:0050701. The regulated release of interleukin 1 from a cell or group of cells. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation by inducing interleukin 2 release and it is involved in the inflammatory response. (more detail) 10 NA Homo sapiens

MSigDB WIG001568 Inhibition of Ribosome Biogenesis by p19(ARF) Inhibition of Ribosome Biogenesis by p19(ARF) (more detail) 10 NA Homo sapiens

Protein Lounge MOX001874 Genes associated with Computational Drug Signature ropinirole Genes associated with Computational Drug Signature ropinirole, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB MOX002812 Genes associated with Computational Drug Signature 2,4 THIAZOLIDINEDIONE Genes associated with Computational Drug Signature 2,4-THIAZOLIDINEDIONE, curated by the Drug Signat (more detail) 10 25990557 Homo sapiens

DSigDB TAX015448 GO:0004865 molecular function protein serine/threonine phosphatase inhibitor activity Stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that ca (more detail) 10 NA Homo sapiens

GOA MOX014383 Genes associated with Computational Drug Signature PD 0173956 Genes associated with Computational Drug Signature PD-0173956, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB WAG000014 reversal of insulin resistance by leptin The insulin resistance of type II diabetes appears to be caused in part by the presence of high leve (more detail) 10 NA Homo sapiens

BioCarta MAX000416 List of the transcription factors up regulated 1 hr after wounding HDF cells (dermal fibroblasts). P27kip is a key inhibitory protein of the cell-cycle progression, which is rapidly downregulated in (more detail) 10 NA Homo sapiens

MSigDB WIG001702 TOB in Osteoblast Signaling TOB in Osteoblast Signaling (more detail) 10 NA Homo sapiens

Protein Lounge MOX002143 Genes associated with Computational Drug Signature Theaflavin Genes associated with Computational Drug Signature Theaflavin, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB TAX015577 GO:0005072 molecular function transforming growth factor beta receptor, cytoplasmic mediator activity Activity of any of the molecules that transmit the signal from a TGF-beta receptor through the cytop (more detail) 10 NA Homo sapiens

GOA MOX014394 Genes associated with Computational Drug Signature PD166326 Genes associated with Computational Drug Signature PD166326, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB MOX017941 Genes associated with Computational Drug Signature Afatinib Genes associated with Computational Drug Signature Afatinib, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB TAX000398 Genes annotated by the GO term GO:0045638. Any process that stops, prevents or reduces the frequency, rate or extent of myeloid cell differentiation. (more detail) 10 NA Homo sapiens

MSigDB MAX002908 Examples of transcription factors whose activities are regulated by MAPK14 [GeneID=1432] phosphorylation. The mitogen-activated protein kinases (MAPKs) are a family of serine/threonine kinases that play an (more detail) 10 NA Homo sapiens

MSigDB MEX001737 Genes associated with Kinase Inhibitor GW612286X Genes associated with Kinase Inhibitor GW612286X, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB TAX013621 GO:0001134 molecular function transcription regulator recruiting activity Interacting selectively and non-covalently with a specific transcription factor, which may be a sing (more detail) 10 NA Homo sapiens

GOA TAX014393 GO:0002713 biological process negative regulation of B cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immun (more detail) 10 NA Homo sapiens

GOA MOX002186 Genes associated with Computational Drug Signature Benzyl 4 hydroxybenzoate Genes associated with Computational Drug Signature Benzyl 4-hydroxybenzoate, curated by the Drug Sig (more detail) 10 25990557 Homo sapiens

DSigDB MOX006144 Genes associated with Computational Drug Signature 5' Guanidinonaltrindole Genes associated with Computational Drug Signature 5'-Guanidinonaltrindole, curated by the Drug Sign (more detail) 10 25990557 Homo sapiens

DSigDB MOX002895 Genes associated with Computational Drug Signature Atiprimod Genes associated with Computational Drug Signature Atiprimod, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB TAX014502 GO:0002890 biological process negative regulation of immunoglobulin mediated immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin med (more detail) 10 NA Homo sapiens

GOA PEX001755 Forkhead: Forkhead domain (more detail) 10 NA Homo sapiens

Pfam TAX013349 GO:0000290 biological process deadenylation dependent decapping of nuclear transcribed mRNA Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a mini (more detail) 10 NA Homo sapiens

GOA FEX002029 Lung not cancer DaSilva03 34genes Table 1. Differential gene expression detected by cDNA array analysis (more detail) 10 12782081 Homo sapiens

GeneSigDB TAX001413 Genes annotated by the GO term GO:0042162. Interacting selectively with telomere associated DNA, usually characterized by highly repetitive sequences. (more detail) 10 NA Homo sapiens

MSigDB TAX001420 Genes annotated by the GO term GO:0003711. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation. (more detail) 10 NA Homo sapiens

MSigDB MOX003319 Genes associated with Computational Drug Signature UNII W39547M0FP Genes associated with Computational Drug Signature UNII-W39547M0FP, curated by the Drug Signature Da (more detail) 10 25990557 Homo sapiens

DSigDB TAX001339 Genes annotated by the GO term GO:0004712. Catalysis of the reaction: ATP + a protein serine/threonine/tyrosine = ADP + protein serine/threonine/tyrosine phosphate. (more detail) 10 NA Homo sapiens

MSigDB TAX027766 GO:0060252 biological process positive regulation of glial cell proliferation Any process that activates or increases the rate or extent of glial cell proliferation. (more detail) 12 NA Homo sapiens

GOA IEI013651 Protein protein interactors of human gene THAP12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THAP12 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI004674 Protein protein interactors of human gene FCER2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FCER2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI005858 Protein protein interactors of human gene HIVEP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HIVEP2 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI012669 Protein protein interactors of human gene SNAPC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNAPC4 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D TAX025757 GO:0046831 biological process regulation of RNA export from nucleus Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nu (more detail) 12 NA Homo sapiens

GOA IEI001797 Protein protein interactors of human gene CARD8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CARD8 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI010449 Protein protein interactors of human gene PREB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PREB (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI010683 Protein protein interactors of human gene PTCD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTCD1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI004884 Protein protein interactors of human gene FOXP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXP1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX026835 GO:0051152 biological process positive regulation of smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of smooth muscle cell differen (more detail) 12 NA Homo sapiens

GOA IEI009784 Protein protein interactors of human gene PFKFB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PFKFB3 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI003710 Protein protein interactors of human gene DNTT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNTT (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI010566 Protein protein interactors of human gene PRR5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRR5 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI012174 Protein protein interactors of human gene SHC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SHC2 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI000632 Protein protein interactors of human gene ANKS1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANKS1B (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI001451 Protein protein interactors of human gene BRWD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRWD1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX026192 GO:0048505 biological process regulation of timing of cell differentiation The process controlling the activation and/or rate at which relatively unspecialized cells acquire s (more detail) 12 NA Homo sapiens

GOA TAX027199 GO:0051798 biological process positive regulation of hair follicle development Any process that activates or increases the frequency, rate or extent of hair follicle development. (more detail) 12 NA Homo sapiens

GOA IEI003718 Protein protein interactors of human gene DOCK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DOCK3 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI010663 Protein protein interactors of human gene PSME3IP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSME3IP1 (SwissProt (more detail) 12 17535438 Homo sapiens

I2D IEI004858 Protein protein interactors of human gene FOXA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXA2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX028887 GO:0070365 biological process hepatocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a hepatocy (more detail) 12 NA Homo sapiens

GOA TAX027627 GO:0060038 biological process cardiac muscle cell proliferation The expansion of a cardiac muscle cell population by cell division. (more detail) 12 NA Homo sapiens

GOA TAX019981 GO:0021602 biological process cranial nerve morphogenesis The process in which the anatomical structure of the cranial nerves are generated and organized. The (more detail) 12 NA Homo sapiens

GOA IEI005194 Protein protein interactors of human gene GIGYF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GIGYF1 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI006149 Protein protein interactors of human gene ID4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ID4 (SwissProt ID=P4 (more detail) 12 17535438 Homo sapiens

I2D TAX024361 GO:0043422 molecular function protein kinase B binding Interacting selectively and non-covalently with protein kinase B, an intracellular kinase that is im (more detail) 12 NA Homo sapiens

GOA TAX022220 GO:0033700 biological process phospholipid efflux The directed movement of a phospholipid out of a cell or organelle. (more detail) 12 NA Homo sapiens

GOA TAX027633 GO:0060044 biological process negative regulation of cardiac muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell pr (more detail) 12 NA Homo sapiens

GOA TAX031776 GO:1900037 biological process regulation of cellular response to hypoxia Any process that modulates the frequency, rate or extent of cellular response to hypoxia. (more detail) 12 NA Homo sapiens

GOA TAX027874 GO:0060391 biological process positive regulation of SMAD protein signal transduction Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathwa (more detail) 12 NA Homo sapiens

GOA IEI006568 Protein protein interactors of human gene ITPRID2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ITPRID2 (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI013766 Protein protein interactors of human gene TLR5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLR5 (SwissProt ID=O (more detail) 12 17535438 Homo sapiens

I2D TAX030192 GO:0080182 biological process histone H3 K4 trimethylation The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the his (more detail) 12 NA Homo sapiens

GOA TAX027676 GO:0060099 biological process regulation of phagocytosis, engulfment Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune (more detail) 12 NA Homo sapiens

GOA TAX034450 GO:2000052 biological process positive regulation of non canonical Wnt signaling pathway Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated (more detail) 12 NA Homo sapiens

GOA TAX027781 GO:0060272 biological process embryonic skeletal joint morphogenesis The process in which the anatomical structures of skeletal joints are generated and organized during (more detail) 12 NA Homo sapiens

GOA IEI002036 Protein protein interactors of human gene CCNB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNB2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI004320 Protein protein interactors of human gene ETHE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ETHE1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI006837 Protein protein interactors of human gene KIF26B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIF26B (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D TAX027612 GO:0060019 biological process radial glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, speci (more detail) 12 NA Homo sapiens

GOA TAX034527 GO:2000194 biological process regulation of female gonad development Any process that modulates the frequency, rate or extent of female gonad development. (more detail) 12 NA Homo sapiens

GOA IEI003119 Protein protein interactors of human gene CTNNA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTNNA2 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI012120 Protein protein interactors of human gene SGK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SGK3 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D TAX024132 GO:0043047 molecular function single stranded telomeric DNA binding Interacting selectively and non-covalently with single-stranded telomere-associated DNA. (more detail) 12 NA Homo sapiens

GOA WIG001057 Genes involved in p75NTR recruits signalling complexes (more detail) 12 NA Homo sapiens

MSigDB TAX000654 Genes annotated by the GO term GO:0043523. Any process that modulates the occurrence or rate of cell death by apoptosis in neurons. (more detail) 12 NA Homo sapiens

MSigDB MOX003652 Genes associated with Computational Drug Signature alprenolol Genes associated with Computational Drug Signature alprenolol, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB TAX014355 GO:0002674 biological process negative regulation of acute inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory (more detail) 12 NA Homo sapiens

GOA MOX015496 Genes associated with Computational Drug Signature Tetradecanoic acid Genes associated with Computational Drug Signature Tetradecanoic acid, curated by the Drug Signature (more detail) 12 25990557 Homo sapiens

DSigDB WAG000027 tnfr2 signaling pathway TNFR2 is the receptor for the 171 amino acid 19 kD TNF(beta) (a.k.a. lymphotoxin). TNF(beta) is prod (more detail) 12 NA Homo sapiens

BioCarta MOX000715 Genes associated with Computational Drug Signature 2 Aminobiphenyl Genes associated with Computational Drug Signature 2-Aminobiphenyl, curated by the Drug Signature Da (more detail) 12 25990557 Homo sapiens

DSigDB MOX007458 Genes associated with Computational Drug Signature calcitriol Genes associated with Computational Drug Signature calcitriol, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB TAX014694 GO:0003323 biological process type B pancreatic cell development The process whose specific outcome is the progression of a type B pancreatic cell over time, from it (more detail) 12 NA Homo sapiens

GOA TAX013953 GO:0001946 biological process lymphangiogenesis Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels. (more detail) 12 NA Homo sapiens

GOA TAX000879 Genes annotated by the GO term GO:0005665. RNA polymerase II, one of three nuclear DNA directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. (more detail) 12 NA Homo sapiens

MSigDB WIG001423 14 3 3 and Cell Cycle Regulation 14-3-3 and Cell Cycle Regulation (more detail) 12 NA Homo sapiens

Protein Lounge TAX018331 GO:0014067 biological process negative regulation of phosphatidylinositol 3 kinase signaling Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction me (more detail) 12 NA Homo sapiens

GOA TAX013813 GO:0001759 biological process organ induction The interaction of two or more cells or tissues that causes them to change their fates and specify t (more detail) 12 NA Homo sapiens

GOA WAG000627 melanocyte development and pigmentation pathway Studies with homozygous knockout mice have suggested that stem cell factor (SCF or KITLG), c-Kit, mi (more detail) 12 NA Homo sapiens

BioCarta WAG000421 multiple antiapoptotic pathways from igf 1r signaling lead to bad phosphorylation IGF-1R, the type 1 receptor for insulin-like growth factor, mediates cell survival and growth in res (more detail) 12 NA Homo sapiens

BioCarta FEX002443 Ovarian Bonome05 13genes Table 2B. Pathway genes unique to LMP ovarian tumors that inhibit tumor progression and metastasis ( (more detail) 12 16288054 Homo sapiens

GeneSigDB WIG000252 AKAP95 role in mitosis and chromosome dynamics The chromatin packaging of the genome is dynamic, changing with the cell cycle and with transcriptio (more detail) 12 NA Homo sapiens

MSigDB MEX001913 Genes associated with Kinase Inhibitor Purvalanol B Genes associated with Kinase Inhibitor Purvalanol B, curated by the Drug Signature Database (DSigDB) (more detail) 12 25990557 Homo sapiens

DSigDB MEX001992 Genes associated with Kinase Inhibitor bisindolylmaleimide i Genes associated with Kinase Inhibitor bisindolylmaleimide i, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB TAX015866 GO:0005675 cellular component holo TFIIH complex A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the lar (more detail) 12 NA Homo sapiens

GOA WAG000853 JNK signaling in the CD4+ TCR pathway (more detail) 12 NA Homo sapiens

NCI-Nature Curated FEX003161 StemCell Lambert09 12genes Table 1. Genes related to apoptosis or cell-cycle arrest whose expression is up- or downregulated by (more detail) 12 19946333 Homo sapiens

GeneSigDB WIG000826 Genes involved in ERKs are inactivated (more detail) 12 NA Homo sapiens

MSigDB MAX002388 A biomarker of plasma signaling proteins that predicts clinical Alzheimer's diagnosis. A molecular test for Alzheimer's disease could lead to better treatment and therapies. We found 18 s (more detail) 12 NA Homo sapiens

MSigDB MOX003662 Genes associated with Computational Drug Signature Aminolevulinic acid Genes associated with Computational Drug Signature Aminolevulinic acid, curated by the Drug Signatur (more detail) 12 25990557 Homo sapiens

DSigDB WIG000661 Genes involved in Activation of Chaperones by ATF6 alpha (more detail) 12 NA Homo sapiens

MSigDB WIG000685 Genes involved in AKT phosphorylates targets in the cytosol (more detail) 12 NA Homo sapiens

MSigDB PEX002387 FGF: Fibroblast growth factor Fibroblast growth factors are a family of proteins involved in growth and differentiation in a wide (more detail) 12 NA Homo sapiens

Pfam MEX001816 Genes associated with Kinase Inhibitor Kinome 490 Genes associated with Kinase Inhibitor Kinome_490, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB WAG001039 erythropoietin mediated neuroprotection through nf kb Erythropoietin (Epo) is most commonly known as the cytokine secreted by the kidneys that stimulates (more detail) 12 NA Homo sapiens

BioCarta TAX001382 Genes annotated by the GO term GO:0032182. Interacting selectively and non covalently with a small conjugating protein such as ubiquitin or a ubiquitin like protein. (more detail) 12 NA Homo sapiens

MSigDB MEX001323 Genes associated with Kinase Inhibitor Tyrphostin AG 1478 Genes associated with Kinase Inhibitor Tyrphostin AG 1478, curated by the Drug Signature Database (D (more detail) 12 25990557 Homo sapiens

DSigDB MEX002340 Genes associated with Kinase Inhibitor Kinome 10 Genes associated with Kinase Inhibitor Kinome_10, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX002367 Genes associated with Kinase Inhibitor Kinome 501 Genes associated with Kinase Inhibitor Kinome_501, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001775 Genes associated with Kinase Inhibitor Kinome 3513 Genes associated with Kinase Inhibitor Kinome_3513, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001209 Genes associated with Kinase Inhibitor 172889 26 8 Genes associated with Kinase Inhibitor 172889-26-8, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB TAX025716 GO:0046697 biological process decidualization The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the (more detail) 20 NA Homo sapiens

GOA TAX029726 GO:0071887 biological process leukocyte apoptotic process Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable (more detail) 20 NA Homo sapiens

GOA IEI007289 Protein protein interactors of human gene LIN9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LIN9 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI005732 Protein protein interactors of human gene HBS1L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HBS1L (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI004609 Protein protein interactors of human gene FBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBP2 (SwissProt ID=O (more detail) 20 17535438 Homo sapiens

I2D IEI002293 Protein protein interactors of human gene CDX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDX2 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI013434 Protein protein interactors of human gene TBCA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBCA (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI006638 Protein protein interactors of human gene KATNA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KATNA1 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI001091 Protein protein interactors of human gene ATP5ME from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP5ME (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI004654 Protein protein interactors of human gene FBXO44 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO44 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI004615 Protein protein interactors of human gene FBXL15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXL15 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI010384 Protein protein interactors of human gene PPP2R2C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP2R2C (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D IEI010204 Protein protein interactors of human gene POLI from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLI (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI002964 Protein protein interactors of human gene CRBN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CRBN (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI014977 Protein protein interactors of human gene WDCP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDCP (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI010973 Protein protein interactors of human gene RAMAC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAMAC (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX026727 GO:0051004 biological process regulation of lipoprotein lipase activity Any process that modulates the activity of the enzyme lipoprotein lipase. (more detail) 20 NA Homo sapiens

GOA TAX033466 GO:1904467 biological process regulation of tumor necrosis factor secretion Any process that modulates the frequency, rate or extent of tumor necrosis factor secretion. (more detail) 20 NA Homo sapiens

GOA IEI009834 Protein protein interactors of human gene PHC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHC3 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI008014 Protein protein interactors of human gene MKKS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MKKS (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI007602 Protein protein interactors of human gene MAGEH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAGEH1 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI014401 Protein protein interactors of human gene TSSK6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TSSK6 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX000736 Genes annotated by the GO term GO:0006405. The directed movement of RNA from the nucleus to the cytoplasm. (more detail) 20 NA Homo sapiens

MSigDB MOX016656 Genes associated with Computational Drug Signature REMIFENTANIL Genes associated with Computational Drug Signature REMIFENTANIL, curated by the Drug Signature Datab (more detail) 20 25990557 Homo sapiens

DSigDB GEX167261 C reactive protein Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for (more detail) 20 21300955 Homo sapiens

GWAS Catalog MOX000131 Genes associated with Computational Drug Signature aminoguanidine Genes associated with Computational Drug Signature aminoguanidine, curated by the Drug Signature Dat (more detail) 20 25990557 Homo sapiens

DSigDB MEX001882 Genes associated with Kinase Inhibitor 918505 84 7 Genes associated with Kinase Inhibitor 918505-84-7, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens

DSigDB FEX001811 Lung Carson04 31genes Table 3a. Response of p53-responsive genes to camptothecin (more detail) 20 15026349 Homo sapiens

GeneSigDB MOX016445 Genes associated with Computational Drug Signature Bosentan Genes associated with Computational Drug Signature Bosentan, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB WIG000194 Canonical Wnt signaling pathway (more detail) 20 NA Homo sapiens

MSigDB GEX000631 endometrial cancer endometrial cancer associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 20 NA Homo sapiens

GAD WIG001190 Genes involved in SHC1 events in ERBB4 signaling (more detail) 20 NA Homo sapiens

MSigDB WAG000420 segmentation clock In most animal species, the anteroposterior body axis is generated by the formation of repeated stru (more detail) 20 NA Homo sapiens

BioCarta MOX016843 Genes associated with Computational Drug Signature Thuringiensin Genes associated with Computational Drug Signature Thuringiensin, curated by the Drug Signature Data (more detail) 20 25990557 Homo sapiens

DSigDB MOX005065 Genes associated with Computational Drug Signature riluzole Genes associated with Computational Drug Signature riluzole, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB MOX000325 Genes associated with Computational Drug Signature DIETHYL PHTHALATE Genes associated with Computational Drug Signature DIETHYL PHTHALATE, curated by the Drug Signature (more detail) 20 25990557 Homo sapiens

DSigDB WIG000332 Corticosteroids and cardioprotection Myocardial infarction damages heart tissue both during the initial ischemia and the subsequent reper (more detail) 20 NA Homo sapiens

MSigDB TAX000414 Genes annotated by the GO term GO:0051051. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells. (more detail) 20 NA Homo sapiens

MSigDB TAX020271 GO:0030038 biological process contractile actin filament bundle assembly Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm (more detail) 14 NA Homo sapiens

GOA TAX034583 GO:2000291 biological process regulation of myoblast proliferation Any process that modulates the frequency, rate or extent of myoblast proliferation. (more detail) 14 NA Homo sapiens

GOA TAX028219 GO:0060973 biological process cell migration involved in heart development The orderly movement of a cell from one site to another that will contribute to the progression of t (more detail) 14 NA Homo sapiens

GOA IEI008782 Protein protein interactors of human gene NFATC2IP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFATC2IP (SwissProt (more detail) 14 17535438 Homo sapiens

I2D IEI015377 Protein protein interactors of human gene ZNF106 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF106 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI012133 Protein protein interactors of human gene SH2B1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH2B1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI001378 Protein protein interactors of human gene BMP6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BMP6 (SwissProt ID=P (more detail) 14 17535438 Homo sapiens

I2D TAX023323 GO:0036295 biological process cellular response to increased oxygen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 14 NA Homo sapiens

GOA TAX023054 GO:0035729 biological process cellular response to hepatocyte growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 14 NA Homo sapiens

GOA TAX023973 GO:0042711 biological process maternal behavior Female behaviors associated with the care and rearing of offspring. (more detail) 14 NA Homo sapiens

GOA TAX028112 GO:0060746 biological process parental behavior A reproductive behavior in which a parent cares for and rears offspring. (more detail) 14 NA Homo sapiens

GOA IEI004082 Protein protein interactors of human gene ELF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELF2 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI013012 Protein protein interactors of human gene SSBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SSBP2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI000372 Protein protein interactors of human gene AGR3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AGR3 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI013756 Protein protein interactors of human gene TLK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLK2 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI007892 Protein protein interactors of human gene MERTK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MERTK (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX024412 GO:0043517 biological process positive regulation of DNA damage response, signal transduction by p53 class mediator Any process that activates, maintains or increases the rate of the cascade of processes induced by t (more detail) 14 NA Homo sapiens

GOA TAX024319 GO:0043369 biological process CD4 positive or CD8 positive, alpha beta T cell lineage commitment The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive l (more detail) 14 NA Homo sapiens

GOA IEI011003 Protein protein interactors of human gene RAPSN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAPSN (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI012463 Protein protein interactors of human gene SLC39A7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC39A7 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI007094 Protein protein interactors of human gene KSR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KSR2 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D TAX023766 GO:0042308 biological process negative regulation of protein import into nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of protei (more detail) 14 NA Homo sapiens

GOA TAX022564 GO:0034620 biological process cellular response to unfolded protein Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 14 NA Homo sapiens

GOA TAX029431 GO:0071391 biological process cellular response to estrogen stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 14 NA Homo sapiens

GOA TAX026104 GO:0048246 biological process macrophage chemotaxis The movement of a macrophage in response to an external stimulus. (more detail) 14 NA Homo sapiens

GOA TAX021344 GO:0032105 biological process negative regulation of response to extracellular stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extra (more detail) 14 NA Homo sapiens

GOA TAX026016 GO:0048009 biological process insulin like growth factor receptor signaling pathway The series of molecular signals generated as a consequence of the insulin-like growth factor recepto (more detail) 14 NA Homo sapiens

GOA TAX025769 GO:0046851 biological process negative regulation of bone remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling. (more detail) 14 NA Homo sapiens

GOA TAX026531 GO:0050700 molecular function CARD domain binding Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a pr (more detail) 14 NA Homo sapiens

GOA TAX031886 GO:1900225 biological process regulation of NLRP3 inflammasome complex assembly Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly. (more detail) 14 NA Homo sapiens

GOA TAX032903 GO:1903351 biological process cellular response to dopamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 14 NA Homo sapiens

GOA IEI002688 Protein protein interactors of human gene CMA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CMA1 (SwissProt ID=P (more detail) 14 17535438 Homo sapiens

I2D IEI003941 Protein protein interactors of human gene EDNRA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EDNRA (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI001550 Protein protein interactors of human gene C1D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C1D (SwissProt ID=Q1 (more detail) 14 17535438 Homo sapiens

I2D IEI008538 Protein protein interactors of human gene NACA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NACA2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI013752 Protein protein interactors of human gene TLE4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLE4 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI014220 Protein protein interactors of human gene TRIM15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM15 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI008056 Protein protein interactors of human gene MMP13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MMP13 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI001437 Protein protein interactors of human gene BRINP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRINP1 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D TAX021347 GO:0032108 biological process negative regulation of response to nutrient levels Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient (more detail) 14 NA Homo sapiens

GOA TAX022836 GO:0035358 biological process regulation of peroxisome proliferator activated receptor signaling pathway Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated re (more detail) 14 NA Homo sapiens

GOA TAX024185 GO:0043149 biological process stress fiber assembly The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A s (more detail) 14 NA Homo sapiens

GOA TAX032902 GO:1903350 biological process response to dopamine Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 14 NA Homo sapiens

GOA IEI008833 Protein protein interactors of human gene NIN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NIN (SwissProt ID=Q8 (more detail) 14 17535438 Homo sapiens

I2D IEI009793 Protein protein interactors of human gene PGAM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PGAM2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI004648 Protein protein interactors of human gene FBXO38 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO38 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D TAX035098 GO:2001212 biological process regulation of vasculogenesis Any process that modulates the frequency, rate or extent of vasculogenesis. (more detail) 14 NA Homo sapiens

GOA TAX033521 GO:1904590 biological process negative regulation of protein import Any process that stops, prevents or reduces the frequency, rate or extent of protein import. (more detail) 14 NA Homo sapiens

GOA IEI005910 Protein protein interactors of human gene HMGN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMGN2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI010254 Protein protein interactors of human gene PON2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PON2 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI011326 Protein protein interactors of human gene RIOK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RIOK1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI011631 Protein protein interactors of human gene RREB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RREB1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI005984 Protein protein interactors of human gene HOXC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXC4 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D WAG001452 sumoylation by ranbp2 regulates transcriptional repression Current data indicates that nuclear pore complex (NPC) RanBP2 (SUMO E3 ligase) protein sumoylates Md (more detail) 14 NA Homo sapiens

BioCarta MOX014243 Genes associated with Computational Drug Signature oleic acid Genes associated with Computational Drug Signature oleic acid, curated by the Drug Signature Databas (more detail) 14 25990557 Homo sapiens

DSigDB FEX002194 Lymphoma Kaminski03 19genes Table 1. NFAT-dependent genes with differential expression in UCB versus AB CD4+ T cells (more detail) 14 12946996 Homo sapiens

GeneSigDB FOX000692 Genes in the cancer module 392 (more detail) 14 NA Homo sapiens

MSigDB MEX000892 Genes associated with Approved Drug dienestrol Genes associated with Approved Drug dienestrol, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB FOX000721 Genes in the cancer module 429 (more detail) 14 NA Homo sapiens

MSigDB TAX000200 Genes annotated by the GO term GO:0006984. Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation. (more detail) 14 NA Homo sapiens

MSigDB MEX002083 Genes associated with Kinase Inhibitor Go 6976 Genes associated with Kinase Inhibitor Go 6976, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX005137 Genes associated with Computational Drug Signature 11032 49 8 Genes associated with Computational Drug Signature 11032-49-8, curated by the Drug Signature Databas (more detail) 14 25990557 Homo sapiens

DSigDB TAX000785 Genes annotated by the GO term GO:0048729. The process by which the anatomical structures of a tissue are generated and organized. Morphogenesis pertains to the creation of form. (more detail) 14 NA Homo sapiens

MSigDB WIG000179 Ras signaling in the CD4+ TCR pathway (more detail) 14 NA Homo sapiens

MSigDB MEX002361 Genes associated with Kinase Inhibitor CHEMBL495696 Genes associated with Kinase Inhibitor CHEMBL495696, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens

DSigDB MEX000511 Genes associated with Approved Drug cladribine Genes associated with Approved Drug cladribine, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX003292 Genes associated with Computational Drug Signature 10'(Z),13'(E),15'(E) Heptadecatrienylhydroquinone Genes associated with Computational Drug Signature 10'(Z),13'(E),15'(E)-Heptadecatrienylhydroquinone (more detail) 14 25990557 Homo sapiens

DSigDB MOX016618 Genes associated with Computational Drug Signature bucladesine Genes associated with Computational Drug Signature bucladesine, curated by the Drug Signature Databa (more detail) 14 25990557 Homo sapiens

DSigDB WAG000449 p38 signaling mediated by MAPKAP kinases (more detail) 14 NA Homo sapiens

NCI-Nature Curated MEX000415 Genes associated with Approved Drug trifluridine Genes associated with Approved Drug trifluridine, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX001718 Genes associated with Kinase Inhibitor Kinome 450 Genes associated with Kinase Inhibitor Kinome_450, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002499 Genes associated with Perturbagen Signature 5224221 Genes associated with Perturbagen Signature 5224221, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens

DSigDB MOX003477 Genes associated with Computational Drug Signature Pazopanib Genes associated with Computational Drug Signature Pazopanib, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB WIG001235 Genes involved in SOS mediated signalling (more detail) 14 NA Homo sapiens

MSigDB WIG000096 IL5 mediated signaling events (more detail) 14 NA Homo sapiens

MSigDB MEX002269 Genes associated with Kinase Inhibitor 841290 80 0 Genes associated with Kinase Inhibitor 841290-80-0, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX000820 Genes associated with Computational Drug Signature 7614 21 3 Genes associated with Computational Drug Signature 7614-21-3, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB MOX002289 Genes associated with Computational Drug Signature Dibenzoylmethane Genes associated with Computational Drug Signature Dibenzoylmethane, curated by the Drug Signature D (more detail) 14 25990557 Homo sapiens

DSigDB MOX007338 Genes associated with Computational Drug Signature BMS 536924 Genes associated with Computational Drug Signature BMS-536924, curated by the Drug Signature Databas (more detail) 14 25990557 Homo sapiens

DSigDB MOX002952 Genes associated with Computational Drug Signature Perfluoroundecanoic acid Genes associated with Computational Drug Signature Perfluoroundecanoic acid, curated by the Drug Sig (more detail) 14 25990557 Homo sapiens

DSigDB TAX014623 GO:0003184 biological process pulmonary valve morphogenesis The process in which the structure of the pulmonary valve is generated and organized. (more detail) 14 NA Homo sapiens

GOA WAG001018 pten dependent cell cycle arrest and apoptosis PTEN is a tumor suppressor gene. Recombint PTEN is capable of dephosphorylating phosphatidylinositol (more detail) 14 NA Homo sapiens

BioCarta MEX002375 Genes associated with Kinase Inhibitor dorsomorphin Genes associated with Kinase Inhibitor dorsomorphin, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens

DSigDB WIG000418 Bone Remodelling Bone density and structure is maintained through a balance of bone resorption by osteoclasts and bon (more detail) 14 NA Homo sapiens

MSigDB IEI009929 Protein protein interactors of human gene PIK3CD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIK3CD (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI007969 Protein protein interactors of human gene MICAL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MICAL1 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D TAX019786 GO:0019724 biological process B cell mediated immunity Any process involved with the carrying out of an immune response by a B cell, through, for instance, (more detail) 18 NA Homo sapiens

GOA IEI001071 Protein protein interactors of human gene ATP2A3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP2A3 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI007150 Protein protein interactors of human gene LARP4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LARP4B (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI006890 Protein protein interactors of human gene KLF11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF11 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI010479 Protein protein interactors of human gene PRKAR1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRKAR1B (SwissProt I (more detail) 18 17535438 Homo sapiens

I2D IEI001697 Protein protein interactors of human gene CACNA1C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CACNA1C (SwissProt I (more detail) 18 17535438 Homo sapiens

I2D IEI002583 Protein protein interactors of human gene CKMT1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CKMT1A (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D TAX028389 GO:0061326 biological process renal tubule development The progression of the renal tubule over time from its formation to the mature form. A renal tubule (more detail) 18 NA Homo sapiens

GOA TAX026743 GO:0051023 biological process regulation of immunoglobulin secretion Any process that modulates the frequency, rate or extent of the regulated release of immunoglobulins (more detail) 18 NA Homo sapiens

GOA TAX022186 GO:0033630 biological process positive regulation of cell adhesion mediated by integrin Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by (more detail) 18 NA Homo sapiens

GOA TAX030673 GO:0097094 biological process craniofacial suture morphogenesis The process in which any suture between cranial and/or facial bones is generated and organized. (more detail) 18 NA Homo sapiens

GOA IEI000839 Protein protein interactors of human gene ARHGEF12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARHGEF12 (SwissProt (more detail) 18 17535438 Homo sapiens

I2D IEI013129 Protein protein interactors of human gene STK38L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STK38L (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI001151 Protein protein interactors of human gene ATXN7L3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATXN7L3 (SwissProt I (more detail) 18 17535438 Homo sapiens

I2D IEI002355 Protein protein interactors of human gene CEP131 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CEP131 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D TAX026639 GO:0050860 biological process negative regulation of T cell receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways ini (more detail) 18 NA Homo sapiens

GOA TAX021460 GO:0032331 biological process negative regulation of chondrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differenti (more detail) 18 NA Homo sapiens

GOA IEI001168 Protein protein interactors of human gene AVPR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AVPR2 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI003554 Protein protein interactors of human gene DIAPH3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIAPH3 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D TAX034555 GO:2000251 biological process positive regulation of actin cytoskeleton reorganization Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorgani (more detail) 18 NA Homo sapiens

GOA IEI006581 Protein protein interactors of human gene JAG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JAG1 (SwissProt ID=P (more detail) 18 17535438 Homo sapiens

I2D TAX019933 GO:0021522 biological process spinal cord motor neuron differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural (more detail) 18 NA Homo sapiens

GOA TAX032471 GO:1902307 biological process positive regulation of sodium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane tr (more detail) 18 NA Homo sapiens

GOA IEI002443 Protein protein interactors of human gene CGN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CGN (SwissProt ID=Q9 (more detail) 18 17535438 Homo sapiens

I2D IEI010216 Protein protein interactors of human gene POLR1H from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR1H (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D FEX003358 Uterine Lucerna06 18genes Table 1. Selected genes up-regulated or down-regulated by sustained EGR-1 expression as delineated f (more detail) 18 16818645 Homo sapiens

GeneSigDB TAX013998 GO:0002011 biological process morphogenesis of an epithelial sheet The process in which the anatomical structures of an epithelial sheet are generated and organized. A (more detail) 18 NA Homo sapiens

GOA WIG000280 Pertussis toxin insensitive CCR5 Signaling in Macrophage The chemokine receptors CCR5 and CXCR4 in macrophages are activated by their peptide ligands and als (more detail) 18 NA Homo sapiens

MSigDB TAX014404 GO:0002726 biological process positive regulation of T cell cytokine production Any process that activates or increases the frequency, rate, or extent of T cell cytokine production (more detail) 18 NA Homo sapiens

GOA MOX017591 Genes associated with Computational Drug Signature pyrimethamine Genes associated with Computational Drug Signature pyrimethamine, curated by the Drug Signature Data (more detail) 18 25990557 Homo sapiens

DSigDB MOX014695 Genes associated with Computational Drug Signature pyrimethamine Genes associated with Computational Drug Signature pyrimethamine, curated by the Drug Signature Data (more detail) 18 25990557 Homo sapiens

DSigDB MEX000802 Genes associated with Approved Drug lapatinib Genes associated with Approved Drug lapatinib, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB WAG000431 chrebp regulation by carbohydrates and camp (more detail) 18 NA Homo sapiens

BioCarta TAX001022 Genes annotated by the GO term GO:0005657. The Y shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. (more detail) 18 NA Homo sapiens

MSigDB MOX002617 Genes associated with Computational Drug Signature Seocalcitol Genes associated with Computational Drug Signature Seocalcitol, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens

DSigDB MOX003406 Genes associated with Computational Drug Signature Muraglitazar Genes associated with Computational Drug Signature Muraglitazar, curated by the Drug Signature Datab (more detail) 18 25990557 Homo sapiens

DSigDB FEX001227 Kidney Wu06 19genes TABLE 3. The top increased genes in the glomeruli of ORG patients compared with controls ( (more detail) 18 16210374 Homo sapiens

GeneSigDB WIG000455 uCalpain and friends in Cell spread The mammalian calpain gene family curently contains 13 distinct large subunit products most of which (more detail) 18 NA Homo sapiens

MSigDB MOX002671 Genes associated with Computational Drug Signature candesartan Genes associated with Computational Drug Signature candesartan, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens

DSigDB MOX001266 Genes associated with Computational Drug Signature Diphenylcyclopropenone Genes associated with Computational Drug Signature Diphenylcyclopropenone, curated by the Drug Signa (more detail) 18 25990557 Homo sapiens

DSigDB MOX001864 Genes associated with Computational Drug Signature Mollugin Genes associated with Computational Drug Signature Mollugin, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB MOX003450 Genes associated with Computational Drug Signature 5 Nitroso 8 quinolinol Genes associated with Computational Drug Signature 5-Nitroso-8-quinolinol, curated by the Drug Signa (more detail) 18 25990557 Homo sapiens

DSigDB MEX000105 Genes associated with Approved Drug valproic acid Genes associated with Approved Drug valproic acid, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB MEX000360 Genes associated with Approved Drug floxuridine Genes associated with Approved Drug floxuridine, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB IEI015869 Protein protein interactors of human gene ZXDC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZXDC (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI003479 Protein protein interactors of human gene DENR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DENR (SwissProt ID=O (more detail) 16 17535438 Homo sapiens

I2D TAX033961 GO:1905517 biological process macrophage migration The orderly movement of a macrophage from one site to another. (more detail) 16 NA Homo sapiens

GOA IEI015341 Protein protein interactors of human gene ZHX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZHX2 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI004015 Protein protein interactors of human gene EID2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EID2 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI010812 Protein protein interactors of human gene PYGO2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PYGO2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI005662 Protein protein interactors of human gene H2BC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2BC1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX031340 GO:0099170 biological process postsynaptic modulation of chemical synaptic transmission Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission. (more detail) 16 NA Homo sapiens

GOA TAX026359 GO:0048821 biological process erythrocyte development The process whose specific outcome is the progression of an erythrocyte over time, from its formatio (more detail) 16 NA Homo sapiens

GOA IEI002029 Protein protein interactors of human gene CCN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCN3 (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D IEI003090 Protein protein interactors of human gene CSTF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSTF1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI009853 Protein protein interactors of human gene PHF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHF7 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI009862 Protein protein interactors of human gene PHLDA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHLDA1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI011640 Protein protein interactors of human gene RRP15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRP15 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI007525 Protein protein interactors of human gene LYPD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LYPD3 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX023670 GO:0042107 biological process cytokine metabolic process The chemical reactions and pathways involving cytokines, any of a group of proteins or glycoproteins (more detail) 16 NA Homo sapiens

GOA TAX029644 GO:0071732 biological process cellular response to nitric oxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 16 NA Homo sapiens

GOA TAX017862 GO:0010155 biological process regulation of proton transport Any process that modulates the frequency, rate or extent of proton transport into, out of or within (more detail) 16 NA Homo sapiens

GOA TAX034379 GO:1990845 biological process adaptive thermogenesis The regulated production of heat in response to short term environmental changes, such as stress, di (more detail) 16 NA Homo sapiens

GOA IEI002462 Protein protein interactors of human gene CHD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD2 (SwissProt ID=O (more detail) 16 17535438 Homo sapiens

I2D IEI012216 Protein protein interactors of human gene SIK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIK1 (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D IEI007139 Protein protein interactors of human gene LANCL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LANCL1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI014005 Protein protein interactors of human gene TNFRSF11A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNFRSF11A (SwissProt (more detail) 16 17535438 Homo sapiens

I2D TAX021807 GO:0032816 biological process positive regulation of natural killer cell activation Any process that activates or increases the frequency, rate or extent of natural killer cell activat (more detail) 16 NA Homo sapiens

GOA TAX023053 GO:0035728 biological process response to hepatocyte growth factor Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 16 NA Homo sapiens

GOA TAX026164 GO:0048385 biological process regulation of retinoic acid receptor signaling pathway Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway (more detail) 16 NA Homo sapiens

GOA TAX034418 GO:2000001 biological process regulation of DNA damage checkpoint Any process that modulates the frequency, rate or extent of a DNA damage checkpoint. (more detail) 16 NA Homo sapiens

GOA IEI015018 Protein protein interactors of human gene WDR62 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR62 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI009974 Protein protein interactors of human gene PIWIL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIWIL1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI005817 Protein protein interactors of human gene HEY1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HEY1 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI013701 Protein protein interactors of human gene TIE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TIE1 (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D IEI000833 Protein protein interactors of human gene ARHGDIB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARHGDIB (SwissProt I (more detail) 16 17535438 Homo sapiens

I2D TAX029308 GO:0071168 biological process protein localization to chromatin Any process in which a protein is transported to, or maintained at, a part of a chromosome that is o (more detail) 16 NA Homo sapiens

GOA IEI009942 Protein protein interactors of human gene PIM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIM2 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI011653 Protein protein interactors of human gene RSF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RSF1 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D TAX021398 GO:0032225 biological process regulation of synaptic transmission, dopaminergic Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the (more detail) 16 NA Homo sapiens

GOA TAX019500 GO:0018216 biological process peptidyl arginine methylation The addition of a methyl group to an arginine residue in a protein. (more detail) 16 NA Homo sapiens

GOA TAX014649 GO:0003222 biological process ventricular trabecula myocardium morphogenesis The process in which the anatomical structures of the trabecular cardiac ventricle muscle are genera (more detail) 16 NA Homo sapiens

GOA MOX001651 Genes associated with Computational Drug Signature 1,3 Dimethylthiourea Genes associated with Computational Drug Signature 1,3-Dimethylthiourea, curated by the Drug Signatu (more detail) 16 25990557 Homo sapiens

DSigDB WAG000211 sprouty regulation of tyrosine kinase signals Four different members of the Sprouty protein family block the cellular proliferation and differenti (more detail) 16 NA Homo sapiens

BioCarta WIG000924 Genes involved in Inflammasomes (more detail) 16 NA Homo sapiens

MSigDB MOX007183 Genes associated with Computational Drug Signature bay 11 7082 Genes associated with Computational Drug Signature bay 11-7082, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB GEX167396 Dupuytren's disease Wnt signaling and Dupuytren's disease. (more detail) 16 21732829 Homo sapiens

GWAS Catalog GEX167637 Rheumatoid arthritis Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese populati (more detail) 16 22446963 Homo sapiens

GWAS Catalog FEX003231 Stomach Mahadevan07 20genes OverExpressed24HrTreatment Table 3a. Overexpressed genes in GIST-S and GIST-R cells after 24 h of treatment with MP470 at 1 m: (more detail) 16 17325667 Homo sapiens

GeneSigDB TAX000309 Genes annotated by the GO term GO:0055088. Any of the processes involved in the maintenance of an internal equilibrium of lipid within an organism or cell. (more detail) 16 NA Homo sapiens

MSigDB TAX000612 Genes annotated by the GO term GO:0050707. Any process that modulates the frequency, rate or extent of the regulated release of cytokines from a cell or group of cells. (more detail) 16 NA Homo sapiens

MSigDB MEX001349 Genes associated with Kinase Inhibitor CHEMBL1982466 Genes associated with Kinase Inhibitor CHEMBL1982466, curated by the Drug Signature Database (DSigDB (more detail) 16 25990557 Homo sapiens

DSigDB MEX001867 Genes associated with Kinase Inhibitor HG 9 91 01 Genes associated with Kinase Inhibitor HG-9-91-01, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB MOX017332 Genes associated with Computational Drug Signature MITHRAMYCIN Genes associated with Computational Drug Signature MITHRAMYCIN, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB FEX002432 Ovarian Horak05 31genes Table 1. Whole-Genome Gene Expression Study Using Affymetrix GeneChips HG-U133A and HG-U133B (more detail) 16 15972852 Homo sapiens

GeneSigDB FEX003430 Viral Keating06 28genes UpRegulated Table 1: Genes undergoing most striking up-regulation at 15 30 120 and 240 minutes post TGF-?1 exp (more detail) 16 16948840 Homo sapiens

GeneSigDB WAG000003 alk in cardiac myocytes Heart formation is cued by a combition of positive and negative sigls from surrounding tissues. Inh (more detail) 16 NA Homo sapiens

BioCarta WIG000246 Role of nicotinic acetylcholine receptors in the regulation of apoptosis Nicotinic acetylcholine receptors are essential for neuromuscular signaling and are also expressed i (more detail) 16 NA Homo sapiens

MSigDB MOX004802 Genes associated with Computational Drug Signature Trifluridine Genes associated with Computational Drug Signature Trifluridine, curated by the Drug Signature Datab (more detail) 16 25990557 Homo sapiens

DSigDB TAX013384 GO:0000380 biological process alternative mRNA splicing, via spliceosome The process of generating multiple mRNA molecules from a given set of exons by differential use of e (more detail) 16 NA Homo sapiens

GOA MOX004175 Genes associated with Computational Drug Signature HARMINE Genes associated with Computational Drug Signature HARMINE, curated by the Drug Signature Database ( (more detail) 16 25990557 Homo sapiens

DSigDB MOX007471 Genes associated with Computational Drug Signature Canertinib dihydrochloride Genes associated with Computational Drug Signature Canertinib dihydrochloride, curated by the Drug S (more detail) 16 25990557 Homo sapiens

DSigDB GEX001355 preterm delivery preterm delivery associated genes. PAGER constructed this gene set by grouping all genes which are a (more detail) 16 NA Homo sapiens

GAD WIG001926 IL 9 signaling pathway IL-9 signaling pathway (more detail) 16 NA Homo sapiens

WikiPathway TAX018325 GO:0014061 biological process regulation of norepinephrine secretion Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine. (more detail) 16 NA Homo sapiens

GOA FEX002417 Ovarian Donninger04 19genes Table 3. Genes up- or downregulated by 1.5-fold (P0.001) identified using PathwayAssist software to (more detail) 16 15361855 Homo sapiens

GeneSigDB WIG000312 Eukaryotic protein translation The scanning translation initiation model suggests that 40S ribosomal subunit preloaded with factors (more detail) 16 NA Homo sapiens

MSigDB WIG001144 Genes involved in Regulation of KIT signaling (more detail) 16 NA Homo sapiens

MSigDB MOX017362 Genes associated with Computational Drug Signature N Acetylmuramyl L alanyl D isoglutamine Genes associated with Computational Drug Signature N-Acetylmuramyl-L-alanyl-D-isoglutamine, curated (more detail) 16 25990557 Homo sapiens

DSigDB MAX003199 Genes changed in DU 145 cells (prostate cancer) in the absence but not presence of a dominant negative form of AKT1 [GeneID=207] upon exposure to HGF [GeneID=3082] for 6 h. The cytokine scatter factor (SF) (hepatocyte growth factor) transduces various biologic actions, inc (more detail) 16 NA Homo sapiens

MSigDB TAX013293 GO:0000176 cellular component nuclear exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuc (more detail) 16 NA Homo sapiens

GOA IEI002055 Protein protein interactors of human gene CCNO from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNO (SwissProt ID=P (more detail) 9 17535438 Homo sapiens

I2D IEI010267 Protein protein interactors of human gene POTEE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POTEE (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI005972 Protein protein interactors of human gene HOXB13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXB13 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI006174 Protein protein interactors of human gene IFI6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFI6 (SwissProt ID=P (more detail) 9 17535438 Homo sapiens

I2D IEI000334 Protein protein interactors of human gene AFAP1L2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AFAP1L2 (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D IEI013964 Protein protein interactors of human gene TMLHE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TMLHE (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D TAX022052 GO:0033240 biological process positive regulation of cellular amine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 9 NA Homo sapiens

GOA TAX030287 GO:0090030 biological process regulation of steroid hormone biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 9 NA Homo sapiens

GOA TAX022937 GO:0035562 biological process negative regulation of chromatin binding Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin bind (more detail) 9 NA Homo sapiens

GOA TAX018181 GO:0010873 biological process positive regulation of cholesterol esterification Any process that increases the frequency, rate or extent of cholesterol esterification. Cholesterol (more detail) 9 NA Homo sapiens

GOA TAX029842 GO:0072124 biological process regulation of glomerular mesangial cell proliferation Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation. (more detail) 9 NA Homo sapiens

GOA TAX021897 GO:0032966 biological process negative regulation of collagen biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 9 NA Homo sapiens

GOA TAX019419 GO:0017162 molecular function aryl hydrocarbon receptor binding Interacting selectively and non-covalently with an aryl hydrocarbon receptor. (more detail) 9 NA Homo sapiens

GOA TAX020997 GO:0031441 biological process negative regulation of mRNA 3' end processing Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing (more detail) 9 NA Homo sapiens

GOA TAX025516 GO:0046322 biological process negative regulation of fatty acid oxidation Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation. (more detail) 9 NA Homo sapiens

GOA TAX033939 GO:1905459 biological process regulation of vascular associated smooth muscle cell apoptotic process Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell a (more detail) 9 NA Homo sapiens

GOA TAX033403 GO:1904350 biological process regulation of protein catabolic process in the vacuole Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole (more detail) 9 NA Homo sapiens

GOA TAX033141 GO:1903800 biological process positive regulation of production of miRNAs involved in gene silencing by miRNA Any process that activates or increases the frequency, rate or extent of production of miRNAs involv (more detail) 9 NA Homo sapiens

GOA TAX034550 GO:2000234 biological process positive regulation of rRNA processing Any process that activates or increases the frequency, rate or extent of rRNA processing. (more detail) 9 NA Homo sapiens

GOA IEI015861 Protein protein interactors of human gene ZSWIM8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZSWIM8 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI003730 Protein protein interactors of human gene DOK5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DOK5 (SwissProt ID=Q (more detail) 9 17535438 Homo sapiens

I2D IEI000971 Protein protein interactors of human gene ASCL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASCL1 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D TAX028940 GO:0070449 cellular component elongin complex A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by (more detail) 9 NA Homo sapiens

GOA TAX022761 GO:0035197 molecular function siRNA binding Interacting selectively and non-covalently with a small interfering RNA, a 21-23 nucleotide RNA that (more detail) 9 NA Homo sapiens

GOA TAX030296 GO:0090043 biological process regulation of tubulin deacetylation Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetyla (more detail) 9 NA Homo sapiens

GOA TAX021235 GO:0031936 biological process negative regulation of chromatin silencing Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing. (more detail) 9 NA Homo sapiens

GOA TAX027639 GO:0060050 biological process positive regulation of protein glycosylation Any process that activates or increases the frequency, rate or extent of the glycosylation of one or (more detail) 9 NA Homo sapiens

GOA TAX026272 GO:0048664 biological process neuron fate determination The process in which a cell becomes capable of differentiating autonomously into a neuron regardless (more detail) 9 NA Homo sapiens

GOA TAX033308 GO:1904153 biological process negative regulation of retrograde protein transport, ER to cytosol Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein tran (more detail) 9 NA Homo sapiens

GOA TAX031993 GO:1901033 biological process positive regulation of response to reactive oxygen species Any process that activates or increases the frequency, rate or extent of response to reactive oxygen (more detail) 9 NA Homo sapiens

GOA TAX027850 GO:0060363 biological process cranial suture morphogenesis The process in which any suture between cranial bones is generated and organized. (more detail) 9 NA Homo sapiens

GOA IEI003840 Protein protein interactors of human gene DUSP16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP16 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI005839 Protein protein interactors of human gene HIF3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HIF3A (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI012784 Protein protein interactors of human gene SOX4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOX4 (SwissProt ID=Q (more detail) 9 17535438 Homo sapiens

I2D IEI000269 Protein protein interactors of human gene ADD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADD3 (SwissProt ID=Q (more detail) 9 17535438 Homo sapiens

I2D IEI007399 Protein protein interactors of human gene LRP1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRP1B (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI000862 Protein protein interactors of human gene ARID3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARID3B (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D TAX021808 GO:0032817 biological process regulation of natural killer cell proliferation Any process that modulates the frequency, rate or extent of natural killer cell proliferation. (more detail) 9 NA Homo sapiens

GOA TAX029193 GO:0070933 biological process histone H4 deacetylation The modification of histone H4 by the removal of one or more acetyl groups. (more detail) 9 NA Homo sapiens

GOA TAX030481 GO:0090308 biological process regulation of methylation dependent chromatin silencing Any process that modulates the rate, frequency, or extent of the repression of transcription by meth (more detail) 9 NA Homo sapiens

GOA TAX029080 GO:0070700 molecular function BMP receptor binding Interacting selectively and non-covalently with a BMP receptor. (more detail) 9 NA Homo sapiens

GOA TAX024083 GO:0042984 biological process regulation of amyloid precursor protein biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 9 NA Homo sapiens

GOA TAX024814 GO:0044666 cellular component MLL3/4 complex A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protei (more detail) 9 NA Homo sapiens

GOA TAX031751 GO:0150065 biological process regulation of deacetylase activity Any process that modulates the frequency, rate or extent of deacetylase activity. (more detail) 9 NA Homo sapiens

GOA TAX031817 GO:1900112 biological process regulation of histone H3 K9 trimethylation Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation. (more detail) 9 NA Homo sapiens

GOA TAX034215 GO:1990314 biological process cellular response to insulin like growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 9 NA Homo sapiens

GOA TAX032038 GO:1901201 biological process regulation of extracellular matrix assembly Any process that modulates the frequency, rate or extent of extracellular matrix assembly. (more detail) 9 NA Homo sapiens

GOA IEI001760 Protein protein interactors of human gene CAMSAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAMSAP2 (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D IEI010555 Protein protein interactors of human gene PRR14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRR14 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI012045 Protein protein interactors of human gene SERPINF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERPINF1 (SwissProt (more detail) 9 17535438 Homo sapiens

I2D IEI012052 Protein protein interactors of human gene SERTAD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERTAD2 (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D TAX028245 GO:0061004 biological process pattern specification involved in kidney development Any developmental process that results in the creation of defined areas or spaces within the kidney (more detail) 9 NA Homo sapiens

GOA TAX022662 GO:0034770 biological process histone H4 K20 methylation The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of (more detail) 9 NA Homo sapiens

GOA TAX022719 GO:0035068 cellular component micro ribonucleoprotein complex A complex containing both protein and micro-RNA (miRNA) molecules. miRNAs are approximately 22 nucle (more detail) 9 NA Homo sapiens

GOA TAX029814 GO:0072074 biological process kidney mesenchyme development The biological process whose specific outcome is the progression of a kidney mesenchyme from an init (more detail) 9 NA Homo sapiens

GOA TAX029262 GO:0071028 biological process nuclear mRNA surveillance The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nu (more detail) 9 NA Homo sapiens

GOA TAX024396 GO:0043497 biological process regulation of protein heterodimerization activity Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting (more detail) 9 NA Homo sapiens

GOA TAX021240 GO:0031943 biological process regulation of glucocorticoid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 9 NA Homo sapiens

GOA TAX027070 GO:0051573 biological process negative regulation of histone H3 K9 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition (more detail) 9 NA Homo sapiens

GOA TAX025229 GO:0045714 biological process regulation of low density lipoprotein particle receptor biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 9 NA Homo sapiens

GOA TAX032511 GO:1902430 biological process negative regulation of amyloid beta formation Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation. (more detail) 9 NA Homo sapiens

GOA TAX033100 GO:1903726 biological process negative regulation of phospholipid metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic (more detail) 9 NA Homo sapiens

GOA TAX034603 GO:2000317 biological process negative regulation of T helper 17 type immune response Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune (more detail) 9 NA Homo sapiens

GOA TAX028128 GO:0060768 biological process regulation of epithelial cell proliferation involved in prostate gland development Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contr (more detail) 9 NA Homo sapiens

GOA IEI015204 Protein protein interactors of human gene ZBTB20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB20 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI002647 Protein protein interactors of human gene CLIC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLIC5 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D TAX030279 GO:0090009 biological process primitive streak formation The developmental process pertaining to the initial formation of the primitive streak from unspecifi (more detail) 9 NA Homo sapiens

GOA TAX018221 GO:0010918 biological process positive regulation of mitochondrial membrane potential Any process that activates or increases the frequency, rate or extent of establishment or extent of (more detail) 9 NA Homo sapiens

GOA TAX021251 GO:0031958 biological process corticosteroid receptor signaling pathway Any series of molecular signals generated as a consequence of a corticosteroid binding to its recept (more detail) 9 NA Homo sapiens

GOA TAX027251 GO:0051901 biological process positive regulation of mitochondrial depolarization Any process that activates, maintains or increases the frequency, rate or extent of the change in th (more detail) 9 NA Homo sapiens

GOA TAX027071 GO:0051574 biological process positive regulation of histone H3 K9 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a (more detail) 9 NA Homo sapiens

GOA TAX033659 GO:1904869 biological process regulation of protein localization to Cajal body Any process that modulates the frequency, rate or extent of protein localization to Cajal body. (more detail) 9 NA Homo sapiens

GOA TAX032506 GO:1902415 biological process regulation of mRNA binding Any process that modulates the frequency, rate or extent of mRNA binding. (more detail) 9 NA Homo sapiens

GOA TAX033844 GO:1905245 biological process regulation of aspartic type peptidase activity Any process that modulates the frequency, rate or extent of aspartic-type peptidase activity. (more detail) 9 NA Homo sapiens

GOA TAX031902 GO:1900247 biological process regulation of cytoplasmic translational elongation Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation. (more detail) 9 NA Homo sapiens

GOA TAX035146 GO:2001279 biological process regulation of unsaturated fatty acid biosynthetic process Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic proc (more detail) 9 NA Homo sapiens

GOA TAX034836 GO:2000644 biological process regulation of receptor catabolic process Any process that modulates the frequency, rate or extent of receptor catabolic process. (more detail) 9 NA Homo sapiens

GOA TAX028137 GO:0060795 biological process cell fate commitment involved in formation of primary germ layer The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of g (more detail) 9 NA Homo sapiens

GOA IEI005644 Protein protein interactors of human gene H1 6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H1-6 (SwissProt ID=P (more detail) 9 17535438 Homo sapiens

I2D IEI006828 Protein protein interactors of human gene KIF20B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIF20B (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI013497 Protein protein interactors of human gene TCF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCF7 (SwissProt ID=P (more detail) 9 17535438 Homo sapiens

I2D TAX022022 GO:0033182 biological process regulation of histone ubiquitination Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a h (more detail) 9 NA Homo sapiens

GOA TAX026609 GO:0050812 biological process regulation of acyl CoA biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 9 NA Homo sapiens

GOA TAX031931 GO:1900402 biological process regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohyd (more detail) 9 NA Homo sapiens

GOA TAX028108 GO:0060742 biological process epithelial cell differentiation involved in prostate gland development The process in which a relatively unspecialized cell acquires specialized features of an epithelial (more detail) 9 NA Homo sapiens

GOA TAX032784 GO:1903069 biological process regulation of ER associated ubiquitin dependent protein catabolic process Any process that modulates the frequency, rate or extent of ER-associated ubiquitin-dependent protei (more detail) 9 NA Homo sapiens

GOA TAX034606 GO:2000320 biological process negative regulation of T helper 17 cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differ (more detail) 9 NA Homo sapiens

GOA IEI002347 Protein protein interactors of human gene CENPV from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CENPV (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI009677 Protein protein interactors of human gene PDE8A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDE8A (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI006903 Protein protein interactors of human gene KLF9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF9 (SwissProt ID=Q (more detail) 9 17535438 Homo sapiens

I2D IEI014020 Protein protein interactors of human gene TNFRSF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNFRSF8 (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D IEI000831 Protein protein interactors of human gene ARHGAP9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARHGAP9 (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D TAX022038 GO:0033210 biological process leptin mediated signaling pathway A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a c (more detail) 9 NA Homo sapiens

GOA TAX027989 GO:0060556 biological process regulation of vitamin D biosynthetic process Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin (more detail) 9 NA Homo sapiens

GOA TAX022427 GO:0034350 biological process regulation of glial cell apoptotic process Any process that modulates the frequency, rate, or extent of glial cell apoptotic process. (more detail) 9 NA Homo sapiens

GOA TAX030308 GO:0090070 biological process positive regulation of ribosome biogenesis Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis (more detail) 9 NA Homo sapiens

GOA TAX029878 GO:0072178 biological process nephric duct morphogenesis The process in which the anatomical structures of the nephric duct are generated and organized. A ne (more detail) 9 NA Homo sapiens

GOA TAX018050 GO:0010692 biological process regulation of alkaline phosphatase activity Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catal (more detail) 9 NA Homo sapiens

GOA TAX019410 GO:0017151 molecular function DEAD/H box RNA helicase binding Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase. (more detail) 9 NA Homo sapiens

GOA TAX020109 GO:0021904 biological process dorsal/ventral neural tube patterning The process in which the neural tube is regionalized in the dorsoventral axis. (more detail) 9 NA Homo sapiens

GOA TAX032271 GO:1901838 biological process positive regulation of transcription of nucleolar large rRNA by RNA polymerase I Any process that activates or increases the frequency, rate or extent of transcription of nuclear la (more detail) 9 NA Homo sapiens

GOA IEI002831 Protein protein interactors of human gene COMMD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD3 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI003008 Protein protein interactors of human gene CRTC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CRTC1 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI011553 Protein protein interactors of human gene RPLP0P6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPLP0P6 (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D TAX022630 GO:0034713 molecular function type I transforming growth factor beta receptor binding Interacting selectively and non-covalently with a type I transforming growth factor beta receptor. (more detail) 9 NA Homo sapiens

GOA TAX022692 GO:0035014 molecular function phosphatidylinositol 3 kinase regulator activity Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can (more detail) 9 NA Homo sapiens

GOA TAX023419 GO:0036500 biological process ATF6 mediated unfolded protein response A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (act (more detail) 9 NA Homo sapiens

GOA TAX019491 GO:0018202 biological process peptidyl histidine modification The modification of peptidyl-histidine. (more detail) 9 NA Homo sapiens

GOA TAX026063 GO:0048143 biological process astrocyte activation A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine (more detail) 9 NA Homo sapiens

GOA TAX033553 GO:1904667 biological process negative regulation of ubiquitin protein ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligas (more detail) 9 NA Homo sapiens

GOA TAX033660 GO:1904871 biological process positive regulation of protein localization to Cajal body Any process that activates or increases the frequency, rate or extent of protein localization to Caj (more detail) 9 NA Homo sapiens

GOA TAX034432 GO:2000018 biological process regulation of male gonad development Any process that modulates the frequency, rate or extent of male gonad development. (more detail) 9 NA Homo sapiens

GOA TAX027915 GO:0060442 biological process branching involved in prostate gland morphogenesis The process in which the branching structure of the prostate gland is generated and organized. A bra (more detail) 9 NA Homo sapiens

GOA TAX028506 GO:0061614 biological process pri miRNA transcription by RNA polymerase II The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polyme (more detail) 9 NA Homo sapiens

GOA IEI010368 Protein protein interactors of human gene PPP1R3C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R3C (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D IEI003992 Protein protein interactors of human gene EGFL7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EGFL7 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI004527 Protein protein interactors of human gene FAM53C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM53C (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI005964 Protein protein interactors of human gene HOXA13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXA13 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI006261 Protein protein interactors of human gene IGLC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGLC1 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D WAG001494 Activation of Pro Caspase 8 (more detail) 9 NA Homo sapiens

Reactome TAX015446 GO:0004862 molecular function cAMP dependent protein kinase inhibitor activity Stops, prevents or reduces the activity of a cAMP-dependent protein kinase. (more detail) 9 NA Homo sapiens

GOA MOX002403 Genes associated with Computational Drug Signature [7 methoxy 8 [2 methyl 3 (3 methylbut 2 enyl)oxiran 2 yl] 2 oxaspiro[2.5]octan 6 yl] N (2 chloroacetyl)carbamate Genes associated with Computational Drug Signature [7-methoxy-8-[2-methyl-3-(3-methylbut-2-enyl)oxir (more detail) 9 25990557 Homo sapiens

DSigDB TAX013638 GO:0001188 biological process RNA polymerase I transcriptional preinitiation complex assembly The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcript (more detail) 9 NA Homo sapiens

GOA TAX014590 GO:0003139 biological process secondary heart field specification The process that results in the delineation of a specific region of the lateral mesoderm into the ar (more detail) 9 NA Homo sapiens

GOA WAG000226 cd40l signaling pathway The CD40 receptor was first associated with expression in B cells and the role it plays through its (more detail) 9 NA Homo sapiens

BioCarta WAG000332 mRNA Processing (more detail) 9 NA Homo sapiens

Reactome MEX001901 Genes associated with Kinase Inhibitor Kinome 709 Genes associated with Kinase Inhibitor Kinome_709, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MOX001676 Genes associated with Computational Drug Signature AG G 31138 Genes associated with Computational Drug Signature AG-G-31138, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens

DSigDB MOX000289 Genes associated with Computational Drug Signature Benzo[ghi]perylene Genes associated with Computational Drug Signature Benzo[ghi]perylene, curated by the Drug Signature (more detail) 9 25990557 Homo sapiens

DSigDB MOX003648 Genes associated with Computational Drug Signature Alloxan Genes associated with Computational Drug Signature Alloxan, curated by the Drug Signature Database ( (more detail) 9 25990557 Homo sapiens

DSigDB MOX002275 Genes associated with Computational Drug Signature Baohuoside I Genes associated with Computational Drug Signature Baohuoside I, curated by the Drug Signature Datab (more detail) 9 25990557 Homo sapiens

DSigDB TAX013597 GO:0001054 molecular function RNA polymerase I activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA (more detail) 9 NA Homo sapiens

GOA TAX014006 GO:0002024 biological process diet induced thermogenesis The process that results in increased metabolic rate in tissues of an organism. It is triggered by t (more detail) 9 NA Homo sapiens

GOA TAX015867 GO:0005677 cellular component chromatin silencing complex Any protein complex that mediates changes in chromatin structure that result in transcriptional sile (more detail) 9 NA Homo sapiens

GOA WAG000658 nitric oxide signaling pathway Glutamatergic-mediated nitric oxide (NO) production occurs via the N-methyl-D-aspartic acid (NMDA) p (more detail) 9 NA Homo sapiens

BioCarta MEX002310 Genes associated with Kinase Inhibitor Tozasertib Genes associated with Kinase Inhibitor Tozasertib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MOX003402 Genes associated with Computational Drug Signature WAY 169916 Genes associated with Computational Drug Signature WAY-169916, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens

DSigDB MOX004738 Genes associated with Computational Drug Signature 2 Thenoyltrifluoroacetone Genes associated with Computational Drug Signature 2-Thenoyltrifluoroacetone, curated by the Drug Si (more detail) 9 25990557 Homo sapiens

DSigDB TAX018240 GO:0010944 biological process negative regulation of transcription by competitive promoter binding Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcri (more detail) 9 NA Homo sapiens

GOA WAG001258 regulation of splicing through sam68 While transcriptiol regulation is often viewed as the most prevalent way extracellular sigls to regu (more detail) 9 NA Homo sapiens

BioCarta WAG001044 carm1 and regulation of the estrogen receptor Several forms of post-translatiol modification regulate protein activities. Recently, protein methy (more detail) 9 NA Homo sapiens

BioCarta TAX001019 Genes annotated by the GO term GO:0008287. A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein. (more detail) 9 NA Homo sapiens

MSigDB MAX002047 Composition of the 2 MDa human PCAF complex. Transcription in eukaryotes is a tightly regulated, multistep process. Gene-specific transcriptional (more detail) 9 NA Homo sapiens

MSigDB TAX000735 Genes annotated by the GO term GO:0006354. The extension of an RNA molecule after transcription initiation by the addition of ribonucleotides catalyzed by an RNA polymerase. (more detail) 9 NA Homo sapiens

MSigDB MEX001049 Genes associated with Approved Drug sunitinib malate Genes associated with Approved Drug sunitinib malate, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens

DSigDB MEX001071 Genes associated with Approved Drug belinostat Genes associated with Approved Drug belinostat, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MOX001818 Genes associated with Computational Drug Signature deferiprone Genes associated with Computational Drug Signature deferiprone, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens

DSigDB MOX000974 Genes associated with Computational Drug Signature 2 Bromohexadecanoic acid Genes associated with Computational Drug Signature 2-Bromohexadecanoic acid, curated by the Drug Sig (more detail) 9 25990557 Homo sapiens

DSigDB MOX004598 Genes associated with Computational Drug Signature Pyocyanin Genes associated with Computational Drug Signature Pyocyanin, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens

DSigDB MOX013366 Genes associated with Computational Drug Signature L thiocitrulline Genes associated with Computational Drug Signature L-thiocitrulline, curated by the Drug Signature D (more detail) 9 25990557 Homo sapiens

DSigDB TAX014763 GO:0003691 molecular function double stranded telomeric DNA binding Interacting selectively and non-covalently with double-stranded telomere-associated DNA. (more detail) 9 NA Homo sapiens

GOA TAX014311 GO:0002579 biological process positive regulation of antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of antigen processing and pre (more detail) 9 NA Homo sapiens

GOA PEX002191 Kunitz BPTI: Kunitz/Bovine pancreatic trypsin inhibitor domain Indicative of a protease inhibitor, usually a serine protease inhibitor. Structure is a disulfide ri (more detail) 9 NA Homo sapiens

Pfam MOX014196 Genes associated with Computational Drug Signature nu6102 Genes associated with Computational Drug Signature nu6102, curated by the Drug Signature Database (D (more detail) 9 25990557 Homo sapiens

DSigDB MAX000144 Set 'Core 9': 'embryonic stem cell' transcription regulators that are preferentially and coordinately overexpressed in the high grade, ER negative breast cancer tumors. Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear, howev (more detail) 9 NA Homo sapiens

MSigDB TAX001241 Genes annotated by the GO term GO:0004709. Catalysis of the phosphorylation and activation of MAP kinase kinases; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases. (more detail) 9 NA Homo sapiens

MSigDB MOX001876 Genes associated with Computational Drug Signature 2,2' Azobis(2 amidinopropane) Genes associated with Computational Drug Signature 2,2'-Azobis(2-amidinopropane), curated by the Dru (more detail) 9 25990557 Homo sapiens

DSigDB WAG001557 p75NTR recruits signalling complexes (more detail) 9 NA Homo sapiens

Reactome WAG000297 NF kB is activated and signals survival (more detail) 9 NA Homo sapiens

Reactome FEX002518 Ovarian Kalloger10 9genes IHCpanel Table 1. A nine-marker immunohistochemical maker panel that can be used to objectively support clas (more detail) 9 21131918 Homo sapiens

GeneSigDB TAX000691 Genes annotated by the GO term GO:0042509. Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. (more detail) 9 NA Homo sapiens

MSigDB MEX001211 Genes associated with Kinase Inhibitor purvalanol A Genes associated with Kinase Inhibitor purvalanol A, curated by the Drug Signature Database (DSigDB) (more detail) 9 25990557 Homo sapiens

DSigDB TAX014757 GO:0003680 molecular function AT DNA binding Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA). (more detail) 9 NA Homo sapiens

GOA TAX014323 GO:0002604 biological process regulation of dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and p (more detail) 9 NA Homo sapiens

GOA MEX001289 Genes associated with Kinase Inhibitor SU11274 Genes associated with Kinase Inhibitor SU11274, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX002931 Genes associated with Perturbagen Signature corbadrine Genes associated with Perturbagen Signature corbadrine, curated by the Drug Signature Database (DSig (more detail) 9 25990557 Homo sapiens

DSigDB MEX001691 Genes associated with Kinase Inhibitor Kinome 413 Genes associated with Kinase Inhibitor Kinome_413, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MOX003381 Genes associated with Computational Drug Signature (19Z) Halichondramide Genes associated with Computational Drug Signature (19Z)-Halichondramide, curated by the Drug Signat (more detail) 9 25990557 Homo sapiens

DSigDB TAX013603 GO:0001075 molecular function transcription factor activity, RNA polymerase II core promoter sequence specific binding involved in preinitiation complex assembly Interacting selectively and non-covalently with a specific DNA sequence in an RNA polymerase II (Pol (more detail) 9 NA Homo sapiens

GOA PEX000235 HATPase c: Histidine kinase , DNA gyrase B , and HSP90 like ATPase This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and (more detail) 9 NA Homo sapiens

Pfam FEX001569 Leukemia Andreeff08 09genes Supplementary Table 6 Genes associated with overall survival. (more detail) 9 18668134 Homo sapiens

GeneSigDB WAG000844 akap95 role in mitosis and chromosome dynamics The chromatin packaging of the genome is dymic, changing with the cell cycle and with transcriptiol (more detail) 9 NA Homo sapiens

BioCarta MAX002595 The 'CLASS 11' set of pro and anti inflammatory cytokines whose expression identifies stage I lung adenocarcinoma patients with poor prognosis. BACKGROUND: A 17-cytokine gene expression signature in noncancerous hepatic tissue from patients wit (more detail) 9 NA Homo sapiens

MSigDB MOX001487 Genes associated with Computational Drug Signature Dipentyl phthalate Genes associated with Computational Drug Signature Dipentyl phthalate, curated by the Drug Signature (more detail) 9 25990557 Homo sapiens

DSigDB MOX000382 Genes associated with Computational Drug Signature METHYL ISOCYANATE Genes associated with Computational Drug Signature METHYL ISOCYANATE, curated by the Drug Signature (more detail) 9 25990557 Homo sapiens

DSigDB MOX002640 Genes associated with Computational Drug Signature Trovafloxacin Genes associated with Computational Drug Signature Trovafloxacin, curated by the Drug Signature Data (more detail) 9 25990557 Homo sapiens

DSigDB MOX013420 Genes associated with Computational Drug Signature leucettamine B Genes associated with Computational Drug Signature leucettamine B, curated by the Drug Signature Dat (more detail) 9 25990557 Homo sapiens

DSigDB TAX014061 GO:0002091 biological process negative regulation of receptor internalization Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalizati (more detail) 9 NA Homo sapiens

GOA TAX014585 GO:0003128 biological process heart field specification The process that results in the delineation of a specific region of the lateral mesoderm into the ar (more detail) 9 NA Homo sapiens

GOA MEX002231 Genes associated with Kinase Inhibitor 1 NM PP1 Genes associated with Kinase Inhibitor 1-NM-PP1, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB IEI015495 Protein protein interactors of human gene ZNF335 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF335 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI015263 Protein protein interactors of human gene ZCCHC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZCCHC3 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI011030 Protein protein interactors of human gene RASL10B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RASL10B (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D IEI005113 Protein protein interactors of human gene GCLC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GCLC (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D IEI006232 Protein protein interactors of human gene IGFBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGFBP1 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI000866 Protein protein interactors of human gene ARID5B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARID5B (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D TAX028819 GO:0070243 biological process regulation of thymocyte apoptotic process Any process that modulates the occurrence or rate of thymocyte death by apoptotic process. (more detail) 11 NA Homo sapiens

GOA TAX018923 GO:0016233 biological process telomere capping A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome (more detail) 11 NA Homo sapiens

GOA IEI015424 Protein protein interactors of human gene ZNF217 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF217 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI015782 Protein protein interactors of human gene ZNF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF8 (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D WEX000049 Inflammasomes The genes related to inflammasomes (innate immunity) in tumor using next-generation sequencer (NGS) (more detail) 11 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI012721 Protein protein interactors of human gene SNX19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNX19 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D TAX026315 GO:0048715 biological process negative regulation of oligodendrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differ (more detail) 11 NA Homo sapiens

GOA IEI008819 Protein protein interactors of human gene NHLH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NHLH1 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI004026 Protein protein interactors of human gene EIF2AK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF2AK3 (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D IEI011813 Protein protein interactors of human gene SBF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SBF1 (SwissProt ID=O (more detail) 11 17535438 Homo sapiens

I2D IEI014204 Protein protein interactors of human gene TRERF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRERF1 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI014460 Protein protein interactors of human gene TUB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TUB (SwissProt ID=P5 (more detail) 11 17535438 Homo sapiens

I2D IEI006469 Protein protein interactors of human gene IQGAP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IQGAP3 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI014017 Protein protein interactors of human gene TNFRSF25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNFRSF25 (SwissProt (more detail) 11 17535438 Homo sapiens

I2D IEI001331 Protein protein interactors of human gene BHLHE41 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BHLHE41 (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D IEI001353 Protein protein interactors of human gene BLID from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BLID (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D TAX017234 GO:0008385 cellular component IkappaB kinase complex A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is (more detail) 11 NA Homo sapiens

GOA IEI002504 Protein protein interactors of human gene CHPF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHPF (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI015516 Protein protein interactors of human gene ZNF384 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF384 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI003333 Protein protein interactors of human gene DCAF16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCAF16 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI009922 Protein protein interactors of human gene PIK3AP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIK3AP1 (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D IEI000126 Protein protein interactors of human gene ACE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACE (SwissProt ID=P1 (more detail) 11 17535438 Homo sapiens

I2D TAX029416 GO:0071372 biological process cellular response to follicle stimulating hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 11 NA Homo sapiens

GOA IEI015751 Protein protein interactors of human gene ZNF76 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF76 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI000563 Protein protein interactors of human gene ANG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANG (SwissProt ID=P0 (more detail) 11 17535438 Homo sapiens

I2D IEI014362 Protein protein interactors of human gene TSLP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TSLP (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI007759 Protein protein interactors of human gene MBD3L2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MBD3L2 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D TAX020684 GO:0030877 cellular component beta catenin destruction complex A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomato (more detail) 11 NA Homo sapiens

GOA IEI003839 Protein protein interactors of human gene DUSP15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP15 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI006204 Protein protein interactors of human gene IFRD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFRD1 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI000526 Protein protein interactors of human gene AMD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AMD1 (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D TAX030770 GO:0097242 biological process amyloid beta clearance The process in which amyloid-beta is removed from the brain via receptors. (more detail) 11 NA Homo sapiens

GOA TAX024446 GO:0043560 molecular function insulin receptor substrate binding Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins (more detail) 11 NA Homo sapiens

GOA TAX033322 GO:1904181 biological process positive regulation of membrane depolarization Any process that activates or increases the frequency, rate or extent of membrane depolarization. (more detail) 11 NA Homo sapiens

GOA TAX028223 GO:0060977 biological process coronary vasculature morphogenesis The process in which the anatomical structures of blood vessels of the heart are generated and organ (more detail) 11 NA Homo sapiens

GOA IEI003855 Protein protein interactors of human gene DUSP9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP9 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D TAX026238 GO:0048596 biological process embryonic camera type eye morphogenesis The process in which the anatomical structures of the eye are generated and organized during embryon (more detail) 11 NA Homo sapiens

GOA IEI002971 Protein protein interactors of human gene CREB3L3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CREB3L3 (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D TAX015893 GO:0005736 cellular component RNA polymerase I complex RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a mu (more detail) 11 NA Homo sapiens

GOA WIG001025 Genes involved in NF kB is activated and signals survival (more detail) 11 NA Homo sapiens

MSigDB WIG001447 ChREBP Regulation in Rattus norvegicus ChREBP Regulation in Rattus norvegicus (more detail) 11 NA Homo sapiens

Protein Lounge MEX001817 Genes associated with Kinase Inhibitor alsterpaullone Genes associated with Kinase Inhibitor alsterpaullone, curated by the Drug Signature Database (DSigD (more detail) 11 25990557 Homo sapiens

DSigDB MOX004368 Genes associated with Computational Drug Signature L mimosine Genes associated with Computational Drug Signature L-mimosine, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens

DSigDB MOX004688 Genes associated with Computational Drug Signature streptonigrin Genes associated with Computational Drug Signature streptonigrin, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens

DSigDB MOX012940 Genes associated with Computational Drug Signature GSK690693 Genes associated with Computational Drug Signature GSK690693, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens

DSigDB TAX017211 GO:0008340 biological process determination of adult lifespan The control of viability and duration in the adult phase of the life-cycle. (more detail) 11 NA Homo sapiens

GOA TAX014612 GO:0003170 biological process heart valve development The progression of a heart valve over time, from its formation to the mature structure. A heart valv (more detail) 11 NA Homo sapiens

GOA WAG001460 b cell survival pathway Physical interactions between intergrin alpha4beta1 heterodimer expressed on B cells and counter rec (more detail) 11 NA Homo sapiens

BioCarta WIG000396 Deregulation of CDK5 in Alzheimers Disease Cyclin-dependent kinase 5 (cdk5), a multi-functional kinase, and its neuron-specific activator p35 a (more detail) 11 NA Homo sapiens

MSigDB MEX001820 Genes associated with Kinase Inhibitor CHEMBL1970317 Genes associated with Kinase Inhibitor CHEMBL1970317, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens

DSigDB MOX004632 Genes associated with Computational Drug Signature RUTHENIUM Genes associated with Computational Drug Signature RUTHENIUM, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens

DSigDB MOX015826 Genes associated with Computational Drug Signature Vatalanib succinate Genes associated with Computational Drug Signature Vatalanib succinate, curated by the Drug Signatur (more detail) 11 25990557 Homo sapiens

DSigDB WAG000213 regulation of transcriptional activity by pml The PML nuclear bodies are ring-shaped nuclear substructures associated with the regulation of trans (more detail) 11 NA Homo sapiens

BioCarta FEX001481 Leukemia Li07 12genes Anti apoptosis Supplementary Table1a Genes over-expressed in the highest PKC-? expressing (quartile 4) DLBCL patien (more detail) 11 17313671 Homo sapiens

GeneSigDB WIG000434 Activation of Src by Protein tyrosine phosphatase alpha Progression through the cell cycle is accompanied by activation of the proto-oncogene c-Src, a prote (more detail) 11 NA Homo sapiens

MSigDB WIG000152 Sumoylation by RanBP2 regulates transcriptional repression (more detail) 11 NA Homo sapiens

MSigDB TAX000637 Genes annotated by the GO term GO:0046425. Any process that modulates the frequency, rate or extent of the JAK STAT signaling pathway. (more detail) 11 NA Homo sapiens

MSigDB MEX002233 Genes associated with Kinase Inhibitor CHEMBL1969102 Genes associated with Kinase Inhibitor CHEMBL1969102, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens

DSigDB MEX002305 Genes associated with Kinase Inhibitor Kinome 248 Genes associated with Kinase Inhibitor Kinome_248, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MOX000159 Genes associated with Computational Drug Signature 3,7,11 trimethyldodeca 2,6,10 trien 1 yl trihydrogen diphosphate Genes associated with Computational Drug Signature 3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydro (more detail) 11 25990557 Homo sapiens

DSigDB MOX000562 Genes associated with Computational Drug Signature Diethyl sulfate Genes associated with Computational Drug Signature Diethyl sulfate, curated by the Drug Signature Da (more detail) 11 25990557 Homo sapiens

DSigDB MOX000850 Genes associated with Computational Drug Signature 6401 97 4 Genes associated with Computational Drug Signature 6401-97-4, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens

DSigDB MOX003951 Genes associated with Computational Drug Signature Diatrizoic acid Genes associated with Computational Drug Signature Diatrizoic acid, curated by the Drug Signature Da (more detail) 11 25990557 Homo sapiens

DSigDB TAX014519 GO:0002923 biological process regulation of humoral immune response mediated by circulating immunoglobulin Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by c (more detail) 11 NA Homo sapiens

GOA TAX000178 Genes annotated by the GO term GO:0006304. The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. (more detail) 11 NA Homo sapiens

MSigDB WIG000314 Erythropoietin mediated neuroprotection through NF kB Erythropoietin (Epo) is most commonly known as the cytokine secreted by the kidneys that stimulates (more detail) 11 NA Homo sapiens

MSigDB TAX014178 GO:0002320 biological process lymphoid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a lymphoid progenito (more detail) 11 NA Homo sapiens

GOA FEX003432 Viral Llovet06 12genes Table 1. Genes Significantly Dysregulated in Early HCC Compared With Dysplatic Nodules; 5 genes were (more detail) 11 17087938 Homo sapiens

GeneSigDB TAX001264 Genes annotated by the GO term GO:0051059. Interacting selectively with NF kappaB, a transcription factor for eukaryotic RNA polymerase II promoters. (more detail) 11 NA Homo sapiens

MSigDB MOX001701 Genes associated with Computational Drug Signature butein Genes associated with Computational Drug Signature butein, curated by the Drug Signature Database (D (more detail) 11 25990557 Homo sapiens

DSigDB MOX003154 Genes associated with Computational Drug Signature Tipifarnib Genes associated with Computational Drug Signature Tipifarnib, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens

DSigDB PEX002167 HMG box: HMG (high mobility group) box (more detail) 11 NA Homo sapiens

Pfam WAG000849 phospholipase c epsilon pathway Proposed model for b2-AR- and prostanoid-receptor-mediated PLC and calcium siglling. Receptors coup (more detail) 11 NA Homo sapiens

BioCarta TAX001444 Genes annotated by the GO term GO:0043130. Interacting selectively and non covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. (more detail) 11 NA Homo sapiens

MSigDB TAX001300 Genes annotated by the GO term GO:0019212. Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. (more detail) 11 NA Homo sapiens

MSigDB MEX000894 Genes associated with Approved Drug tiotixene Genes associated with Approved Drug tiotixene, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MEX000620 Genes associated with Approved Drug adapalene Genes associated with Approved Drug adapalene, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MOX000409 Genes associated with Computational Drug Signature PIMARIC ACID Genes associated with Computational Drug Signature PIMARIC ACID, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens

DSigDB MOX005581 Genes associated with Computational Drug Signature 2,4 PYRIDINEDICARBOXYLIC ACID Genes associated with Computational Drug Signature 2,4-PYRIDINEDICARBOXYLIC ACID, curated by the Dru (more detail) 11 25990557 Homo sapiens

DSigDB WAG000861 Sumoylation by RanBP2 regulates transcriptional repression (more detail) 11 NA Homo sapiens

NCI-Nature Curated TAX000404 Genes annotated by the GO term GO:0048585. Any process that stops, prevents or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. (more detail) 11 NA Homo sapiens

MSigDB WIG001576 Alternative Complement Pathway Alternative Complement Pathway (more detail) 11 NA Homo sapiens

Protein Lounge MOX003741 Genes associated with Computational Drug Signature BETAMETHASONE VALERATE Genes associated with Computational Drug Signature BETAMETHASONE VALERATE, curated by the Drug Signa (more detail) 11 25990557 Homo sapiens

DSigDB MAX000055 Genes whose expression peaked at 20 min after stimulation of HeLa cells with EGF [GeneID=1950]. Signaling pathways invoke interplays between forward signaling and feedback to drive robust cellular (more detail) 11 NA Homo sapiens

MSigDB TAX000392 Genes annotated by the GO term GO:0051346. Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. (more detail) 11 NA Homo sapiens

MSigDB TAX000394 Genes annotated by the GO term GO:0032387. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. (more detail) 11 NA Homo sapiens

MSigDB MEX001203 Genes associated with Kinase Inhibitor Cdk2 Inhibitor IV, NU6140 Genes associated with Kinase Inhibitor Cdk2 Inhibitor IV, NU6140, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens

DSigDB MOX000124 Genes associated with Computational Drug Signature Alantolactone Genes associated with Computational Drug Signature Alantolactone, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens

DSigDB MOX000985 Genes associated with Computational Drug Signature Chromium (Iii) Chloride Genes associated with Computational Drug Signature Chromium (Iii) Chloride, curated by the Drug Sign (more detail) 11 25990557 Homo sapiens

DSigDB MOX000825 Genes associated with Computational Drug Signature Lead dinitrate Genes associated with Computational Drug Signature Lead dinitrate, curated by the Drug Signature Dat (more detail) 11 25990557 Homo sapiens

DSigDB IEI012244 Protein protein interactors of human gene SIX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIX1 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D IEI006539 Protein protein interactors of human gene ITGB1BP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ITGB1BP1 (SwissProt (more detail) 17 17535438 Homo sapiens

I2D IEI004216 Protein protein interactors of human gene EPHB6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPHB6 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI010921 Protein protein interactors of human gene RABIF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RABIF (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI013469 Protein protein interactors of human gene TCAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCAF1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI007716 Protein protein interactors of human gene MARCHF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MARCHF7 (SwissProt I (more detail) 17 17535438 Homo sapiens

I2D IEI007678 Protein protein interactors of human gene MAP7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP7 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D IEI008033 Protein protein interactors of human gene MLLT10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MLLT10 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI015384 Protein protein interactors of human gene ZNF131 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF131 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI002630 Protein protein interactors of human gene CLEC3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLEC3B (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI013490 Protein protein interactors of human gene TCF20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCF20 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI007898 Protein protein interactors of human gene METAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene METAP2 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D TAX023350 GO:0036342 biological process post anal tail morphogenesis The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular reg (more detail) 17 NA Homo sapiens

GOA TAX027284 GO:0051957 biological process positive regulation of amino acid transport Any process that activates, maintains or increases the frequency, rate or extent of the directed mov (more detail) 17 NA Homo sapiens

GOA TAX034833 GO:2000641 biological process regulation of early endosome to late endosome transport Any process that modulates the frequency, rate or extent of early endosome to late endosome transpor (more detail) 17 NA Homo sapiens

GOA IEI001425 Protein protein interactors of human gene BRD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRD2 (SwissProt ID=P (more detail) 17 17535438 Homo sapiens

I2D TAX020554 GO:0030539 biological process male genitalia development The process whose specific outcome is the progression of the male genitalia over time, from its form (more detail) 17 NA Homo sapiens

GOA TAX031821 GO:1900116 biological process extracellular negative regulation of signal transduction Any negative regulation of signal transduction that takes place in extracellular region. (more detail) 17 NA Homo sapiens

GOA IEI003287 Protein protein interactors of human gene DACH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DACH1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI005234 Protein protein interactors of human gene GKAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GKAP1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI005443 Protein protein interactors of human gene GPR37 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GPR37 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI013535 Protein protein interactors of human gene TEAD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TEAD1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI007923 Protein protein interactors of human gene MEX3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEX3B (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX025222 GO:0045683 biological process negative regulation of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development. (more detail) 17 NA Homo sapiens

GOA IEI008816 Protein protein interactors of human gene NGLY1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NGLY1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX028238 GO:0060997 biological process dendritic spine morphogenesis The process in which the anatomical structures of a dendritic spine are generated and organized. A d (more detail) 17 NA Homo sapiens

GOA TAX032926 GO:1903392 biological process negative regulation of adherens junction organization Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organ (more detail) 17 NA Homo sapiens

GOA IEI008876 Protein protein interactors of human gene NLRC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NLRC4 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI004638 Protein protein interactors of human gene FBXO24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO24 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI011906 Protein protein interactors of human gene SDF2L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SDF2L1 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI005583 Protein protein interactors of human gene GTF2H2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2H2 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D TAX029820 GO:0072080 biological process nephron tubule development The progression of a nephron tubule over time, from its initial formation to the mature structure. A (more detail) 17 NA Homo sapiens

GOA TAX031820 GO:1900115 biological process extracellular regulation of signal transduction Any regulation of signal transduction that takes place in the extracellular region. (more detail) 17 NA Homo sapiens

GOA IEI002065 Protein protein interactors of human gene CCR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCR2 (SwissProt ID=P (more detail) 17 17535438 Homo sapiens

I2D IEI008932 Protein protein interactors of human gene NOL6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOL6 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D IEI002720 Protein protein interactors of human gene CNKSR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNKSR2 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI010903 Protein protein interactors of human gene RAB6B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAB6B (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI005676 Protein protein interactors of human gene H2BU1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2BU1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX020267 GO:0030033 biological process microvillus assembly Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. (more detail) 17 NA Homo sapiens

GOA TAX033882 GO:1905331 biological process negative regulation of morphogenesis of an epithelium Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epi (more detail) 17 NA Homo sapiens

GOA IEI011085 Protein protein interactors of human gene RBM34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM34 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D MAX002312 Down regulated genes in MM1.S cells (multiple myeloma) treated with adaphostin [PubChem=387042], a tyrosine kinase inhibitor with anticancer properties. Here we show the antimyeloma cytotoxicity of adaphostin and carried out expression profiling of adap (more detail) 17 NA Homo sapiens

MSigDB MOX004892 Genes associated with Computational Drug Signature Phorbol 12,13 dibutyrate Genes associated with Computational Drug Signature Phorbol 12,13-dibutyrate, curated by the Drug Sig (more detail) 17 25990557 Homo sapiens

DSigDB MOX003740 Genes associated with Computational Drug Signature betamethasone Genes associated with Computational Drug Signature betamethasone, curated by the Drug Signature Data (more detail) 17 25990557 Homo sapiens

DSigDB WAG000427 corticosteroids and cardioprotection Myocardial infarction damages heart tissue both during the initial ischemia and the subsequent reper (more detail) 17 NA Homo sapiens

BioCarta TAX000188 Genes annotated by the GO term GO:0048598. The process by which anatomical structures are generated and organized during the embryonic phase. Morphogenesis pertains to the creation of form. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. (more detail) 17 NA Homo sapiens

MSigDB MEX002171 Genes associated with Kinase Inhibitor PF 03814735 Genes associated with Kinase Inhibitor PF-03814735, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB MEX003681 Genes associated with Perturbagen Signature naftifine Genes associated with Perturbagen Signature naftifine, curated by the Drug Signature Database (DSigD (more detail) 17 25990557 Homo sapiens

DSigDB FEX000452 Breast Nimeus Malmstrom06 20genes Table 3. A list of the top-10 unrestricted genes (a) and drug genes (b) were ranked using Pearson co (more detail) 17 17023159 Homo sapiens

GeneSigDB MAX001750 Cluster 7: genes up regulated in SW260 cells (colon cancer) by curcumin and sulindac [PubChem=969516;5352]. The short-chain fatty acid butyrate, produced by microbial fermentation of dietary fiber in the larg (more detail) 17 NA Homo sapiens

MSigDB MAX002623 Cluster 3: genes changed in primary keratinocytes by UVB irradiation. UV radiation is the most important environmental skin aggressor, causing cancer and other problems. (more detail) 17 NA Homo sapiens

MSigDB TAX014309 GO:0002577 biological process regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of antigen processing and presentation. (more detail) 17 NA Homo sapiens

GOA MOX012704 Genes associated with Computational Drug Signature floxuridine Genes associated with Computational Drug Signature floxuridine, curated by the Drug Signature Databa (more detail) 17 25990557 Homo sapiens

DSigDB TAX013374 GO:0000339 molecular function RNA cap binding Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative locate (more detail) 17 NA Homo sapiens

GOA GEX001542 stroke, ischemic stroke, ischemic associated genes. PAGER constructed this gene set by grouping all genes which are a (more detail) 17 NA Homo sapiens

GAD WAG000006 regulation of cell cycle progression by plk3 The focus of this pathway is to illustrate the role of Polo-like Kise 3 (Plk3 also known as Prk and (more detail) 17 NA Homo sapiens

BioCarta MAX001635 Genes up regulated in BEAS 2B cells (bronchial epithelium) stimulated with IL13 [GeneID=3596] on days 1 to 3 and then rested for the next 3 days (repeated stimulation or memory model) Our objective was to establish an experimental model of a self-sustained and bistable extracellular (more detail) 17 NA Homo sapiens

MSigDB WIG000204 PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. na (more detail) 17 NA Homo sapiens

MSigDB PEX002548 Helicase C: Helicase conserved C terminal domain The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide (more detail) 17 NA Homo sapiens

Pfam MOX002222 Genes associated with Computational Drug Signature calphostin C Genes associated with Computational Drug Signature calphostin C, curated by the Drug Signature Datab (more detail) 17 25990557 Homo sapiens

DSigDB FEX002869 StemCell Weber05 18genes Table 1 Genes identi?ed as hypermethylated in SW48 cancer cells (more detail) 17 16007088 Homo sapiens

GeneSigDB MOX005020 Genes associated with Computational Drug Signature leukotriene D4 Genes associated with Computational Drug Signature leukotriene D4, curated by the Drug Signature Dat (more detail) 17 25990557 Homo sapiens

DSigDB MAX001220 Genes whose promoters contain TP53 [GeneID=7157] response elements. Little is known about the mechanisms that regulate differential transactivation by p53. We developed (more detail) 17 NA Homo sapiens

MSigDB MAX003083 Genes identified as hypermethylated in SW48 cells (colon cancer). Cytosine methylation is required for mammalian development and is often perturbed in human cancer. T (more detail) 17 NA Homo sapiens

MSigDB MEX000435 Genes associated with Approved Drug methylergonovine Genes associated with Approved Drug methylergonovine, curated by the Drug Signature Database (DSigDB (more detail) 17 25990557 Homo sapiens

DSigDB MEX000872 Genes associated with Approved Drug melphalan Genes associated with Approved Drug melphalan, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB IEI004548 Protein protein interactors of human gene FAM83H from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM83H (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI012795 Protein protein interactors of human gene SP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SP2 (SwissProt ID=Q0 (more detail) 13 17535438 Homo sapiens

I2D IEI013609 Protein protein interactors of human gene TFDP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TFDP2 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI000205 Protein protein interactors of human gene ACY1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACY1 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI014421 Protein protein interactors of human gene TTC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTC3 (SwissProt ID=P (more detail) 13 17535438 Homo sapiens

I2D TAX021100 GO:0031650 biological process regulation of heat generation Any process that modulates the rate or extent of heat generation. (more detail) 13 NA Homo sapiens

GOA TAX034625 GO:2000345 biological process regulation of hepatocyte proliferation Any process that modulates the frequency, rate or extent of hepatocyte proliferation. (more detail) 13 NA Homo sapiens

GOA TAX030527 GO:0090399 biological process replicative senescence A cell aging process associated with the dismantling of a cell as a response to telomere shortening (more detail) 13 NA Homo sapiens

GOA TAX025114 GO:0045472 biological process response to ether Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 13 NA Homo sapiens

GOA TAX034843 GO:2000651 biological process positive regulation of sodium ion transmembrane transporter activity Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane tr (more detail) 13 NA Homo sapiens

GOA IEI001857 Protein protein interactors of human gene CBLL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CBLL1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI002053 Protein protein interactors of human gene CCNL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNL1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI012966 Protein protein interactors of human gene SRGAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRGAP1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI006959 Protein protein interactors of human gene KLK7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLK7 (SwissProt ID=P (more detail) 13 17535438 Homo sapiens

I2D TAX017790 GO:0009886 biological process post embryonic animal morphogenesis The process, occurring after animal embryonic development, by which anatomical structures are genera (more detail) 13 NA Homo sapiens

GOA TAX033102 GO:1903729 biological process regulation of plasma membrane organization Any process that modulates the frequency, rate or extent of plasma membrane organization. (more detail) 13 NA Homo sapiens

GOA IEI009380 Protein protein interactors of human gene OTULIN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OTULIN (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI009642 Protein protein interactors of human gene PDAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDAP1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI003540 Protein protein interactors of human gene DHX33 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHX33 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI010386 Protein protein interactors of human gene PPP2R3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP2R3A (SwissProt I (more detail) 13 17535438 Homo sapiens

I2D IEI006483 Protein protein interactors of human gene IRF2BP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IRF2BP1 (SwissProt I (more detail) 13 17535438 Homo sapiens

I2D IEI000035 Protein protein interactors of human gene ABCB11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABCB11 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI000589 Protein protein interactors of human gene ANKRA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANKRA2 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI006926 Protein protein interactors of human gene KLHL23 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHL23 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D TAX031571 GO:0106057 biological process negative regulation of calcineurin mediated signaling Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated si (more detail) 13 NA Homo sapiens

GOA TAX028258 GO:0061029 biological process eyelid development in camera type eye The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyeli (more detail) 13 NA Homo sapiens

GOA TAX021735 GO:0032725 biological process positive regulation of granulocyte macrophage colony stimulating factor production Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage col (more detail) 13 NA Homo sapiens

GOA TAX033800 GO:1905153 biological process regulation of membrane invagination Any process that modulates the frequency, rate or extent of membrane invagination. (more detail) 13 NA Homo sapiens

GOA IEI004078 Protein protein interactors of human gene ELAVL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELAVL2 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI011765 Protein protein interactors of human gene SACS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SACS (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI004607 Protein protein interactors of human gene FBN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBN3 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI011863 Protein protein interactors of human gene SCML2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCML2 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI010321 Protein protein interactors of human gene PPIP5K1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPIP5K1 (SwissProt I (more detail) 13 17535438 Homo sapiens

I2D TAX022169 GO:0033604 biological process negative regulation of catecholamine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release (more detail) 13 NA Homo sapiens

GOA TAX023654 GO:0042074 biological process cell migration involved in gastrulation The migration of individual cells within the blastocyst to help establish the multi-layered body pla (more detail) 13 NA Homo sapiens

GOA TAX018274 GO:0010988 biological process regulation of low density lipoprotein particle clearance Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearan (more detail) 13 NA Homo sapiens

GOA TAX029437 GO:0071397 biological process cellular response to cholesterol Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 13 NA Homo sapiens

GOA TAX024451 GO:0043568 biological process positive regulation of insulin like growth factor receptor signaling pathway Any process that increases the frequency, rate or extent of insulin-like growth factor receptor sign (more detail) 13 NA Homo sapiens

GOA TAX035026 GO:2001044 biological process regulation of integrin mediated signaling pathway Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway. (more detail) 13 NA Homo sapiens

GOA IEI003852 Protein protein interactors of human gene DUSP6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP6 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX029882 GO:0072182 biological process regulation of nephron tubule epithelial cell differentiation Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell different (more detail) 13 NA Homo sapiens

GOA TAX028859 GO:0070306 biological process lens fiber cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lens fiber c (more detail) 13 NA Homo sapiens

GOA TAX029164 GO:0070885 biological process negative regulation of calcineurin NFAT signaling cascade Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT s (more detail) 13 NA Homo sapiens

GOA TAX020077 GO:0021846 biological process cell proliferation in forebrain The creation of greater cell numbers in the forebrain due to cell division of progenitor cells. (more detail) 13 NA Homo sapiens

GOA TAX026262 GO:0048642 biological process negative regulation of skeletal muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue (more detail) 13 NA Homo sapiens

GOA TAX027880 GO:0060397 biological process JAK STAT cascade involved in growth hormone signaling pathway The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activate (more detail) 13 NA Homo sapiens

GOA IEI010429 Protein protein interactors of human gene PRCC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRCC (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI004298 Protein protein interactors of human gene ESF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ESF1 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI007868 Protein protein interactors of human gene MEF2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEF2B (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX018193 GO:0010885 biological process regulation of cholesterol storage Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the acc (more detail) 13 NA Homo sapiens

GOA IEI000968 Protein protein interactors of human gene ASCC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASCC1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX018087 GO:0010745 biological process negative regulation of macrophage derived foam cell differentiation Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentia (more detail) 13 NA Homo sapiens

GOA TAX025302 GO:0045838 biological process positive regulation of membrane potential Any process that activates or increases the frequency, rate or extent of establishment or extent of (more detail) 13 NA Homo sapiens

GOA IEI008622 Protein protein interactors of human gene NCF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCF4 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI002690 Protein protein interactors of human gene CMBL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CMBL (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI013125 Protein protein interactors of human gene STK33 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STK33 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI013394 Protein protein interactors of human gene TASOR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TASOR (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D MAX000819 Proteins identified by mass spectrometry in complexes containing ALKBH8 [GeneID=91801]. tRNA nucleosides are extensively modified to ensure their proper function in translation. However, m (more detail) 13 NA Homo sapiens

MSigDB WAG000641 bone remodeling Bone density and structure is maintained through a balance of bone resorption by osteoclasts and bon (more detail) 13 NA Homo sapiens

BioCarta MOX003368 Genes associated with Computational Drug Signature DMAT Genes associated with Computational Drug Signature DMAT, curated by the Drug Signature Database (DSi (more detail) 13 25990557 Homo sapiens

DSigDB MOX013132 Genes associated with Computational Drug Signature Indatraline hydrochloride Genes associated with Computational Drug Signature Indatraline hydrochloride, curated by the Drug Si (more detail) 13 25990557 Homo sapiens

DSigDB MOX012137 Genes associated with Computational Drug Signature Cytomel Genes associated with Computational Drug Signature Cytomel, curated by the Drug Signature Database ( (more detail) 13 25990557 Homo sapiens

DSigDB MEX000929 Genes associated with Approved Drug calcitriol Genes associated with Approved Drug calcitriol, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MEX000933 Genes associated with Approved Drug vitamin d3 Genes associated with Approved Drug vitamin d3, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MEX002319 Genes associated with Kinase Inhibitor Kinome 491 Genes associated with Kinase Inhibitor Kinome_491, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB PEX002042 Ldl recept a: Low density lipoprotein receptor domain class A (more detail) 13 NA Homo sapiens

Pfam GEX001550 suicide suicide associated genes. PAGER constructed this gene set by grouping all genes which are associated (more detail) 13 NA Homo sapiens

GAD WAG000262 Cellular roles of Anthrax toxin (more detail) 13 NA Homo sapiens

NCI-Nature Curated WAG001281 S1P2 pathway (more detail) 13 NA Homo sapiens

NCI-Nature Curated FEX000488 Breast Chanock07 16genes Table 1 Somatic alterations by region in breast cancer re-sequence analysis (more detail) 13 17224074 Homo sapiens

GeneSigDB TAX000112 Genes annotated by the GO term GO:0045165. The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one cell zygote) or within a developmental field. (more detail) 13 NA Homo sapiens

MSigDB MOX000927 Genes associated with Computational Drug Signature herbimycin a Genes associated with Computational Drug Signature herbimycin a, curated by the Drug Signature Datab (more detail) 13 25990557 Homo sapiens

DSigDB MOX015215 Genes associated with Computational Drug Signature SU11652 Genes associated with Computational Drug Signature SU11652, curated by the Drug Signature Database ( (more detail) 13 25990557 Homo sapiens

DSigDB FEX002159 Lymphoma Lam01 23genes SuppTable 5. Proliferation genes (more detail) 13 11597333 Homo sapiens

GeneSigDB TAX000018 Genes annotated by the GO term GO:0007568. The inherent decline over time, from the optimal fertility and viability of early maturity, that may precede death and may be preceded by other indications, such as sterility. (more detail) 13 NA Homo sapiens

MSigDB MEX002777 Genes associated with Perturbagen Signature carbamazepine Genes associated with Perturbagen Signature carbamazepine, curated by the Drug Signature Database (D (more detail) 13 25990557 Homo sapiens

DSigDB MEX001472 Genes associated with Kinase Inhibitor PI 103 Genes associated with Kinase Inhibitor PI-103, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MEX003018 Genes associated with Perturbagen Signature dienestrol Genes associated with Perturbagen Signature dienestrol, curated by the Drug Signature Database (DSig (more detail) 13 25990557 Homo sapiens

DSigDB MOX002768 Genes associated with Computational Drug Signature Penconazole Genes associated with Computational Drug Signature Penconazole, curated by the Drug Signature Databa (more detail) 13 25990557 Homo sapiens

DSigDB MOX017647 Genes associated with Computational Drug Signature methoxychlor Genes associated with Computational Drug Signature methoxychlor, curated by the Drug Signature Datab (more detail) 13 25990557 Homo sapiens

DSigDB MAX001067 Genes from selected recurrently amplified regions in soft tissue tumors with supernumerary ring chromosomes. Ring chromosomes and/or giant marker chromosomes have been observed in a variety of human tumor type (more detail) 13 NA Homo sapiens

MSigDB MAX002586 Genes up regulated in 293 cells (embryonic kidney) expressing polymorphic variants S427G (SNP ID=rs2070235) or I624M (SNP ID=rs11556379) of BMYB [GeneID=4605]. The B-MYB proto-oncogene is a transcription factor belonging to the MYB family that is frequently ov (more detail) 13 NA Homo sapiens

MSigDB MAX003117 Genes down regulated in NCI H2170 cells (lung cancer) upon induction of resistance to cisplatin [PubChem=2767]. In recent years, most cDNA microarray studies of chemotherapeutic drug resistance have not considere (more detail) 13 NA Homo sapiens

MSigDB MEX002003 Genes associated with Kinase Inhibitor Kinome 474 Genes associated with Kinase Inhibitor Kinome_474, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB TAX016701 GO:0006957 biological process complement activation, alternative pathway Any process involved in the activation of any of the steps of the alternative pathway of the complem (more detail) 13 NA Homo sapiens

GOA GEX166603 LDL cholesterol Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cho (more detail) 13 18193044 Homo sapiens

GWAS Catalog MEX002141 Genes associated with Kinase Inhibitor roscovitine Genes associated with Kinase Inhibitor roscovitine, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MOX000393 Genes associated with Computational Drug Signature N,N Dimethyl 4 nitrosoaniline Genes associated with Computational Drug Signature N,N-Dimethyl-4-nitrosoaniline, curated by the Dru (more detail) 13 25990557 Homo sapiens

DSigDB MOX002247 Genes associated with Computational Drug Signature DENSPM Genes associated with Computational Drug Signature DENSPM, curated by the Drug Signature Database (D (more detail) 13 25990557 Homo sapiens

DSigDB TAX018399 GO:0014855 biological process striated muscle cell proliferation The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell po (more detail) 13 NA Homo sapiens

GOA TAX013868 GO:0001829 biological process trophectodermal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a trophect (more detail) 13 NA Homo sapiens

GOA TAX014202 GO:0002363 biological process alpha beta T cell lineage commitment The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell. (more detail) 13 NA Homo sapiens

GOA WIG000278 CBL mediated ligand induced downregulation of EGF receptors As with many cell-surface receptors, activation of the EGF receptor can result in receptor internali (more detail) 13 NA Homo sapiens

MSigDB TAX001333 Genes annotated by the GO term GO:0008276. Catalysis of the transfer of a methyl group (CH3 ) to a protein. (more detail) 13 NA Homo sapiens

MSigDB FEX001575 Leukemia Sanchez Guijo08 14genes SuppTable2a Genes involved in proliferation/apoptosis (more detail) 13 18722011 Homo sapiens

GeneSigDB FEX002624 Prostate Floryk05 17genes SuppTable 3. Common down-regulated genes at 12 h of TB and MPA treatment (more detail) 13 16357169 Homo sapiens

GeneSigDB MOX001087 Genes associated with Computational Drug Signature Diacerein Genes associated with Computational Drug Signature Diacerein, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens

DSigDB MEX001844 Genes associated with Kinase Inhibitor CHEMBL1999931 Genes associated with Kinase Inhibitor CHEMBL1999931, curated by the Drug Signature Database (DSigDB (more detail) 13 25990557 Homo sapiens

DSigDB MOX003359 Genes associated with Computational Drug Signature XCT790 Genes associated with Computational Drug Signature XCT790, curated by the Drug Signature Database (D (more detail) 13 25990557 Homo sapiens

DSigDB MOX002878 Genes associated with Computational Drug Signature Ginsenoside Rg3 Genes associated with Computational Drug Signature Ginsenoside Rg3, curated by the Drug Signature Da (more detail) 13 25990557 Homo sapiens

DSigDB MOX002670 Genes associated with Computational Drug Signature 1,1,1 trifluorohenicosa 6,9,12,15 tetraen 2 one Genes associated with Computational Drug Signature 1,1,1-trifluorohenicosa-6,9,12,15-tetraen-2-one, (more detail) 13 25990557 Homo sapiens

DSigDB TAX018023 GO:0010642 biological process negative regulation of platelet derived growth factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived g (more detail) 13 NA Homo sapiens

GOA MOX016121 Genes associated with Computational Drug Signature 5,6 BENZOFLAVONE Genes associated with Computational Drug Signature 5,6-BENZOFLAVONE, curated by the Drug Signature D (more detail) 13 25990557 Homo sapiens

DSigDB MOX004869 Genes associated with Computational Drug Signature 2,2' BIPYRIDINE Genes associated with Computational Drug Signature 2,2'-BIPYRIDINE, curated by the Drug Signature Da (more detail) 13 25990557 Homo sapiens

DSigDB MOX000197 Genes associated with Computational Drug Signature naringin Genes associated with Computational Drug Signature naringin, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX013472 Genes associated with Computational Drug Signature LITHOCHOLIC ACID Genes associated with Computational Drug Signature LITHOCHOLIC ACID, curated by the Drug Signature D (more detail) 15 25990557 Homo sapiens

DSigDB TAX015862 GO:0005671 cellular component Ada2/Gcn5/Ada3 transcription activator complex A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of tra (more detail) 15 NA Homo sapiens

GOA MOX017640 Genes associated with Computational Drug Signature N Methyl N nitrosourea Genes associated with Computational Drug Signature N-Methyl-N-nitrosourea, curated by the Drug Signa (more detail) 15 25990557 Homo sapiens

DSigDB FEX003416 Viral Stoff Khalili06 15genes Common Table 1 Descriptive microarray results of apoptosis genes common to human and mouse liver tissue sli (more detail) 15 16410819 Homo sapiens

GeneSigDB FEX002383 Mouth Ruutu04 15genes Table V. Genes which increased expression (two-fold or more) detected in both UT-SCC cell lines (UT- (more detail) 15 15517866 Homo sapiens

GeneSigDB TAX013780 GO:0001702 biological process gastrulation with mouth forming second A gastrulation process in which the initial invagination becomes the anus and the mouth forms second (more detail) 15 NA Homo sapiens

GOA MAX000512 Proteins that regulate activity of PRKDC [GeneID=5591]. Double-strand breaks (DSBs) arise endogenously during normal cellular processes and exogenously by g (more detail) 15 NA Homo sapiens

MSigDB FEX002604 Prostate Haudenschild04 18genes Table 2. BMP signaling molecules affected by BMP-6 in prostate cancer (more detail) 15 15548695 Homo sapiens

GeneSigDB FEX000792 Breast Staaf10 15genes SuppTable 4. Genes implicated in breast cancer or immune response and present in the HDPP gene signa (more detail) 15 20231686 Homo sapiens

GeneSigDB WIG001467 DNA Damage Induced 14 3 3Sigma Signaling DNA Damage Induced 14-3-3Sigma Signaling (more detail) 15 NA Homo sapiens

Protein Lounge MEX004120 Genes associated with Perturbagen Signature semustine Genes associated with Perturbagen Signature semustine, curated by the Drug Signature Database (DSigD (more detail) 15 25990557 Homo sapiens

DSigDB MOX004769 Genes associated with Computational Drug Signature TITANIUM Genes associated with Computational Drug Signature TITANIUM, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB WIG000059 ErbB receptor signaling network (more detail) 15 NA Homo sapiens

MSigDB MOX013762 Genes associated with Computational Drug Signature MLS002320748 Genes associated with Computational Drug Signature MLS002320748, curated by the Drug Signature Datab (more detail) 15 25990557 Homo sapiens

DSigDB WIG000772 Genes involved in CREB phosphorylation through the activation of CaMKII (more detail) 15 NA Homo sapiens

MSigDB MOX003456 Genes associated with Computational Drug Signature PCI 24781 Genes associated with Computational Drug Signature PCI-24781, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX000896 Genes associated with Computational Drug Signature Ciprofibrate Genes associated with Computational Drug Signature Ciprofibrate, curated by the Drug Signature Datab (more detail) 15 25990557 Homo sapiens

DSigDB MOX017797 Genes associated with Computational Drug Signature Bexarotene Genes associated with Computational Drug Signature Bexarotene, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens

DSigDB MAX000735 Nearest neighbors of LYL1 [GeneID=4066], based on the close agreement of their expression profiles with that of LYL1 in pediatric T cell acute lymphoblastic leukemia (T ALL). Human T cell leukemias can arise from oncogenes activated by specific chromosomal translocations inv (more detail) 15 NA Homo sapiens

MSigDB WIG000778 Genes involved in Beta catenin phosphorylation cascade (more detail) 15 NA Homo sapiens

MSigDB WIG001192 Genes involved in SHC mediated signalling (more detail) 15 NA Homo sapiens

MSigDB MEX002159 Genes associated with Kinase Inhibitor Kinome 6 Genes associated with Kinase Inhibitor Kinome_6, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB MOX002767 Genes associated with Computational Drug Signature tazarotene Genes associated with Computational Drug Signature tazarotene, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens

DSigDB MOX002299 Genes associated with Computational Drug Signature Carboxyamidotriazole Genes associated with Computational Drug Signature Carboxyamidotriazole, curated by the Drug Signatu (more detail) 15 25990557 Homo sapiens

DSigDB WIG000438 TACI and BCMA stimulation of B cell immune responses. TACI and BCMA signal transduction pathway that enhances cell survival APRIL and BAFF (also called TA (more detail) 15 NA Homo sapiens

MSigDB WIG000355 IL 3 signaling pathway Interleukin-3 promotes the proliferation and differentiation of hematopoietic cells through binding (more detail) 15 NA Homo sapiens

MSigDB MOX004540 Genes associated with Computational Drug Signature pindolol Genes associated with Computational Drug Signature pindolol, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MAX001137 Genes distinguishing vincristine [PubChem=5978] resistant and sensitive B lineage ALL; here genes down regulated in the drug resistant samples. Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percen (more detail) 15 NA Homo sapiens

MSigDB MOX001364 Genes associated with Computational Drug Signature CHLOROBENZENE Genes associated with Computational Drug Signature CHLOROBENZENE, curated by the Drug Signature Data (more detail) 15 25990557 Homo sapiens

DSigDB MOX000415 Genes associated with Computational Drug Signature ZINEB Genes associated with Computational Drug Signature ZINEB, curated by the Drug Signature Database (DS (more detail) 15 25990557 Homo sapiens

DSigDB TAX013924 GO:0001911 biological process negative regulation of leukocyte mediated cytotoxicity Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity. (more detail) 15 NA Homo sapiens

GOA IEI011627 Protein protein interactors of human gene RRAGD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRAGD (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D TAX022349 GO:0034162 biological process toll like receptor 9 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 9. (more detail) 15 NA Homo sapiens

GOA TAX026723 GO:0050998 molecular function nitric oxide synthase binding Interacting selectively and non-covalently with the enzyme nitric-oxide synthase. (more detail) 15 NA Homo sapiens

GOA TAX033604 GO:1904754 biological process positive regulation of vascular associated smooth muscle cell migration Any process that activates or increases the frequency, rate or extent of vascular associated smooth (more detail) 15 NA Homo sapiens

GOA IEI005737 Protein protein interactors of human gene HCFC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HCFC2 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI007559 Protein protein interactors of human gene MACROH2A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MACROH2A2 (SwissProt (more detail) 15 17535438 Homo sapiens

I2D IEI014813 Protein protein interactors of human gene UTP15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UTP15 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI001385 Protein protein interactors of human gene BMS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BMS1 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI015065 Protein protein interactors of human gene WNT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WNT1 (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D IEI010021 Protein protein interactors of human gene PLAAT4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLAAT4 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI004117 Protein protein interactors of human gene ELP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELP4 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI011534 Protein protein interactors of human gene RPL36A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL36A (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI006957 Protein protein interactors of human gene KLK5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLK5 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI010088 Protein protein interactors of human gene PLEKHO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLEKHO1 (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D IEI011276 Protein protein interactors of human gene RHEBL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RHEBL1 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI011697 Protein protein interactors of human gene RUBCN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RUBCN (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI012870 Protein protein interactors of human gene SPHK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPHK1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D TAX027998 GO:0060571 biological process morphogenesis of an epithelial fold The morphogenetic process in which an epithelial sheet bends along a linear axis. (more detail) 15 NA Homo sapiens

GOA TAX030292 GO:0090036 biological process regulation of protein kinase C signaling Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the (more detail) 15 NA Homo sapiens

GOA TAX016794 GO:0007143 biological process female meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female (more detail) 15 NA Homo sapiens

GOA TAX030301 GO:0090051 biological process negative regulation of cell migration involved in sprouting angiogenesis Any process that decreases the frequency, rate or extent of cell migration involved in sprouting ang (more detail) 15 NA Homo sapiens

GOA IEI002698 Protein protein interactors of human gene CMSS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CMSS1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI006288 Protein protein interactors of human gene IL10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL10 (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D IEI006892 Protein protein interactors of human gene KLF13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF13 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI007382 Protein protein interactors of human gene LRBA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRBA (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D IEI014307 Protein protein interactors of human gene TRMT61A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRMT61A (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D IEI008130 Protein protein interactors of human gene MPHOSPH8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MPHOSPH8 (SwissProt (more detail) 15 17535438 Homo sapiens

I2D TAX027651 GO:0060065 biological process uterus development The reproductive developmental process whose specific outcome is the progression of the uterus over (more detail) 15 NA Homo sapiens

GOA IEI008971 Protein protein interactors of human gene NPAT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NPAT (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI003395 Protein protein interactors of human gene DDIT4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDIT4 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI000096 Protein protein interactors of human gene ABRAXAS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABRAXAS1 (SwissProt (more detail) 15 17535438 Homo sapiens

I2D IEI007565 Protein protein interactors of human gene MADD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MADD (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D TAX021686 GO:0032645 biological process regulation of granulocyte macrophage colony stimulating factor production Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulati (more detail) 15 NA Homo sapiens

GOA TAX023659 GO:0042089 biological process cytokine biosynthetic process The chemical reactions and pathways resulting in the formation of cytokines, any of a group of prote (more detail) 15 NA Homo sapiens

GOA IEI011000 Protein protein interactors of human gene RAPGEF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAPGEF6 (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D IEI004677 Protein protein interactors of human gene FCGR1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FCGR1A (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI012185 Protein protein interactors of human gene SHKBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SHKBP1 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI012140 Protein protein interactors of human gene SH2D3C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH2D3C (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI012160 Protein protein interactors of human gene SH3PXD2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH3PXD2A (SwissProt (more detail) 15 17535438 Homo sapiens

I2D IEI001618 Protein protein interactors of human gene C4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C4A (SwissProt ID=P0 (more detail) 15 17535438 Homo sapiens

I2D TAX022538 GO:0034518 cellular component RNA cap binding complex Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the (more detail) 15 NA Homo sapiens

GOA TAX018183 GO:0010875 biological process positive regulation of cholesterol efflux Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux i (more detail) 15 NA Homo sapiens

GOA TAX027840 GO:0060347 biological process heart trabecula formation The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a s (more detail) 15 NA Homo sapiens

GOA IEI005377 Protein protein interactors of human gene GP6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GP6 (SwissProt ID=Q9 (more detail) 15 17535438 Homo sapiens

I2D IEI006759 Protein protein interactors of human gene KDM3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM3A (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI006770 Protein protein interactors of human gene KDM6B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM6B (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI013599 Protein protein interactors of human gene TFAP2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TFAP2B (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D TAX031714 GO:0140131 biological process positive regulation of lymphocyte chemotaxis Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis. (more detail) 15 NA Homo sapiens

GOA IEI015240 Protein protein interactors of human gene ZC3H12A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZC3H12A (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D IEI010724 Protein protein interactors of human gene PTOV1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTOV1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D TAX029406 GO:0071354 biological process cellular response to interleukin 6 Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 15 NA Homo sapiens

GOA TAX029703 GO:0071850 biological process mitotic cell cycle arrest The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) (more detail) 15 NA Homo sapiens

GOA TAX022428 GO:0034351 biological process negative regulation of glial cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic (more detail) 8 NA Homo sapiens

GOA TAX024935 GO:0045080 biological process positive regulation of chemokine biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 8 NA Homo sapiens

GOA TAX029093 GO:0070734 biological process histone H3 K27 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of (more detail) 8 NA Homo sapiens

GOA TAX029907 GO:0072217 biological process negative regulation of metanephros development Any process that decreases the rate, frequency or extent of metanephros development. Metanephros dev (more detail) 8 NA Homo sapiens

GOA TAX021873 GO:0032927 biological process positive regulation of activin receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the activity of any activin (more detail) 8 NA Homo sapiens

GOA TAX026626 GO:0050847 biological process progesterone receptor signaling pathway Any series of molecular signals generated as a consequence of a progesterone binding to its receptor (more detail) 8 NA Homo sapiens

GOA TAX020094 GO:0021877 biological process forebrain neuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop i (more detail) 8 NA Homo sapiens

GOA TAX032516 GO:1902459 biological process positive regulation of stem cell population maintenance Any process that activates or increases the frequency, rate or extent of stem cell population mainte (more detail) 8 NA Homo sapiens

GOA TAX034608 GO:2000322 biological process regulation of glucocorticoid receptor signaling pathway Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathwa (more detail) 8 NA Homo sapiens

GOA IEI015344 Protein protein interactors of human gene ZIC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZIC2 (SwissProt ID=O (more detail) 8 17535438 Homo sapiens

I2D IEI002453 Protein protein interactors of human gene CHAT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHAT (SwissProt ID=P (more detail) 8 17535438 Homo sapiens

I2D IEI003674 Protein protein interactors of human gene DNAJC21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJC21 (SwissProt I (more detail) 8 17535438 Homo sapiens

I2D IEI004969 Protein protein interactors of human gene FZD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FZD1 (SwissProt ID=Q (more detail) 8 17535438 Homo sapiens

I2D IEI005992 Protein protein interactors of human gene HOXD12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXD12 (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D IEI008089 Protein protein interactors of human gene MOB3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MOB3A (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI008482 Protein protein interactors of human gene MYO5C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYO5C (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D TAX021833 GO:0032875 biological process regulation of DNA endoreduplication Any process that modulates the frequency, rate or extent of DNA endoreduplication. (more detail) 8 NA Homo sapiens

GOA TAX021857 GO:0032909 biological process regulation of transforming growth factor beta2 production Any process that modulates the frequency, rate, or extent of production of transforming growth facto (more detail) 8 NA Homo sapiens

GOA TAX021236 GO:0031937 biological process positive regulation of chromatin silencing Any process that activates or increases the frequency, rate or extent of chromatin silencing. (more detail) 8 NA Homo sapiens

GOA TAX021944 GO:0033034 biological process positive regulation of myeloid cell apoptotic process Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic pro (more detail) 8 NA Homo sapiens

GOA TAX034101 GO:1905906 biological process regulation of amyloid fibril formation Any process that modulates the frequency, rate or extent of amyloid fibril formation. (more detail) 8 NA Homo sapiens

GOA TAX033740 GO:1905005 biological process regulation of epithelial to mesenchymal transition involved in endocardial cushion formation Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition inv (more detail) 8 NA Homo sapiens

GOA TAX032129 GO:1901409 biological process positive regulation of phosphorylation of RNA polymerase II C terminal domain Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA poly (more detail) 8 NA Homo sapiens

GOA TAX034655 GO:2000381 biological process negative regulation of mesoderm development Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development. (more detail) 8 NA Homo sapiens

GOA TAX034705 GO:2000465 biological process regulation of glycogen (starch) synthase activity Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity. (more detail) 8 NA Homo sapiens

GOA TAX034717 GO:2000480 biological process negative regulation of cAMP dependent protein kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein (more detail) 8 NA Homo sapiens

GOA TAX033772 GO:1905064 biological process negative regulation of vascular smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle (more detail) 8 NA Homo sapiens

GOA TAX034915 GO:2000767 biological process positive regulation of cytoplasmic translation Any process that activates or increases the frequency, rate or extent of cytoplasmic translation. (more detail) 8 NA Homo sapiens

GOA IEI002444 Protein protein interactors of human gene CGNL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CGNL1 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI015402 Protein protein interactors of human gene ZNF174 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF174 (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D TAX021319 GO:0032071 biological process regulation of endodeoxyribonuclease activity Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydr (more detail) 8 NA Homo sapiens

GOA TAX029533 GO:0071550 biological process death inducing signaling complex assembly A process of protein complex assembly in which the arrangement and bonding together of the set of co (more detail) 8 NA Homo sapiens

GOA TAX025688 GO:0046643 biological process regulation of gamma delta T cell activation Any process that modulates the frequency, rate or extent of gamma-delta T cell activation. (more detail) 8 NA Homo sapiens

GOA TAX025184 GO:0045631 biological process regulation of mechanoreceptor differentiation Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation. (more detail) 8 NA Homo sapiens

GOA TAX031925 GO:1900376 biological process regulation of secondary metabolite biosynthetic process Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic proces (more detail) 8 NA Homo sapiens

GOA TAX034914 GO:2000766 biological process negative regulation of cytoplasmic translation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation (more detail) 8 NA Homo sapiens

GOA IEI015049 Protein protein interactors of human gene WFIKKN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WFIKKN1 (SwissProt I (more detail) 8 17535438 Homo sapiens

I2D IEI002834 Protein protein interactors of human gene COMMD5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD5 (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D IEI003746 Protein protein interactors of human gene DPF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DPF3 (SwissProt ID=Q (more detail) 8 17535438 Homo sapiens

I2D IEI004958 Protein protein interactors of human gene FXYD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FXYD1 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI011544 Protein protein interactors of human gene RPL41 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL41 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI011789 Protein protein interactors of human gene SAP30L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SAP30L (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D TAX028924 GO:0070424 biological process regulation of nucleotide binding oligomerization domain containing signaling pathway Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization do (more detail) 8 NA Homo sapiens

GOA TAX023150 GO:0035912 biological process dorsal aorta morphogenesis The process in which the anatomical structures of the dorsal aorta are generated and organized. The (more detail) 8 NA Homo sapiens

GOA TAX019114 GO:0016593 cellular component Cdc73/Paf1 complex A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcri (more detail) 8 NA Homo sapiens

GOA TAX026357 GO:0048819 biological process regulation of hair follicle maturation Any process that modulates the frequency, rate or extent of hair follicle maturation. (more detail) 8 NA Homo sapiens

GOA TAX026055 GO:0048096 biological process chromatin mediated maintenance of transcription Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once establis (more detail) 8 NA Homo sapiens

GOA TAX032146 GO:1901526 biological process positive regulation of mitophagy Any process that activates or increases the frequency, rate or extent of mitophagy. (more detail) 8 NA Homo sapiens

GOA TAX032916 GO:1903376 biological process regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsi (more detail) 8 NA Homo sapiens

GOA TAX027778 GO:0060267 biological process positive regulation of respiratory burst Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, d (more detail) 8 NA Homo sapiens

GOA TAX028296 GO:0061085 biological process regulation of histone H3 K27 methylation Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3- (more detail) 8 NA Homo sapiens

GOA TAX028733 GO:0070099 biological process regulation of chemokine mediated signaling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated (more detail) 8 NA Homo sapiens

GOA TAX022635 GO:0034720 biological process histone H3 K4 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the his (more detail) 8 NA Homo sapiens

GOA TAX017290 GO:0008469 molecular function histone arginine N methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine (more detail) 8 NA Homo sapiens

GOA TAX018150 GO:0010835 biological process regulation of protein ADP ribosylation Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ri (more detail) 8 NA Homo sapiens

GOA TAX029894 GO:0072201 biological process negative regulation of mesenchymal cell proliferation Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenc (more detail) 8 NA Homo sapiens

GOA TAX032535 GO:1902510 biological process regulation of apoptotic DNA fragmentation Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation. (more detail) 8 NA Homo sapiens

GOA TAX032709 GO:1902947 biological process regulation of tau protein kinase activity Any process that modulates the frequency, rate or extent of tau-protein kinase activity. (more detail) 8 NA Homo sapiens

GOA TAX032721 GO:1902959 biological process regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity inv (more detail) 8 NA Homo sapiens

GOA IEI008557 Protein protein interactors of human gene NANOG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NANOG (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI008659 Protein protein interactors of human gene NDRG2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NDRG2 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI004258 Protein protein interactors of human gene ERF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERF (SwissProt ID=P5 (more detail) 8 17535438 Homo sapiens

I2D IEI010879 Protein protein interactors of human gene RAB38 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAB38 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI004332 Protein protein interactors of human gene ETV7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ETV7 (SwissProt ID=Q (more detail) 8 17535438 Homo sapiens

I2D IEI004380 Protein protein interactors of human gene EZH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EZH1 (SwissProt ID=Q (more detail) 8 17535438 Homo sapiens

I2D IEI005983 Protein protein interactors of human gene HOXC13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXC13 (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D TAX034465 GO:2000074 biological process regulation of type B pancreatic cell development Any process that modulates the frequency, rate or extent of pancreatic B cell development. (more detail) 8 NA Homo sapiens

GOA TAX030048 GO:0072542 molecular function protein phosphatase activator activity Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosp (more detail) 8 NA Homo sapiens

GOA TAX030068 GO:0072577 biological process endothelial cell apoptotic process Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or l (more detail) 8 NA Homo sapiens

GOA TAX023356 GO:0036353 biological process histone H2A K119 monoubiquitination The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in (more detail) 8 NA Homo sapiens

GOA TAX030349 GO:0090130 biological process tissue migration The process in which the population of cells that make up a tissue undergo directed movement. (more detail) 8 NA Homo sapiens

GOA TAX031122 GO:0098779 biological process positive regulation of mitophagy in response to mitochondrial depolarization Any process that activates or increases the frequency, rate or extent of mitophagy in response to mi (more detail) 8 NA Homo sapiens

GOA TAX021562 GO:0032453 molecular function histone demethylase activity (H3 K4 specific) Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein. (more detail) 8 NA Homo sapiens

GOA TAX026246 GO:0048617 biological process embryonic foregut morphogenesis The process in which the anatomical structures of the foregut are generated and organized, during th (more detail) 8 NA Homo sapiens

GOA TAX032817 GO:1903147 biological process negative regulation of autophagy of mitochondrion Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradati (more detail) 8 NA Homo sapiens

GOA TAX034130 GO:1990000 biological process amyloid fibril formation The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet struct (more detail) 8 NA Homo sapiens

GOA TAX033407 GO:1904354 biological process negative regulation of telomere capping Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping. (more detail) 8 NA Homo sapiens

GOA TAX033140 GO:1903799 biological process negative regulation of production of miRNAs involved in gene silencing by miRNA Any process that stops, prevents or reduces the frequency, rate or extent of production of miRNAs in (more detail) 8 NA Homo sapiens

GOA TAX028666 GO:0062043 biological process positive regulation of cardiac epithelial to mesenchymal transition Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchy (more detail) 8 NA Homo sapiens

GOA TAX034593 GO:2000304 biological process positive regulation of ceramide biosynthetic process Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic proce (more detail) 8 NA Homo sapiens

GOA IEI001816 Protein protein interactors of human gene CASP12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASP12 (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D IEI009038 Protein protein interactors of human gene NR4A3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR4A3 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI011777 Protein protein interactors of human gene SAMD4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SAMD4B (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D IEI005586 Protein protein interactors of human gene GTF2H5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2H5 (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D IEI012470 Protein protein interactors of human gene SLC41A3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC41A3 (SwissProt I (more detail) 8 17535438 Homo sapiens

I2D IEI006142 Protein protein interactors of human gene ICE2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ICE2 (SwissProt ID=Q (more detail) 8 17535438 Homo sapiens

I2D IEI006614 Protein protein interactors of human gene JTB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JTB (SwissProt ID=O7 (more detail) 8 17535438 Homo sapiens

I2D IEI000928 Protein protein interactors of human gene ARRDC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARRDC4 (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D TAX022015 GO:0033170 molecular function protein DNA loading ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the assembly of a protein or protei (more detail) 8 NA Homo sapiens

GOA TAX034995 GO:2000980 biological process regulation of inner ear receptor cell differentiation Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation. (more detail) 8 NA Homo sapiens

GOA TAX022518 GO:0034475 biological process U4 snRNA 3' end processing Any process involved in forming the mature 3' end of a U4 snRNA molecule. (more detail) 8 NA Homo sapiens

GOA TAX025083 GO:0045357 biological process regulation of interferon beta biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 8 NA Homo sapiens

GOA TAX021983 GO:0033129 biological process positive regulation of histone phosphorylation Any process that activates or increases the frequency, rate or extent of the addition of one or more (more detail) 8 NA Homo sapiens

GOA TAX022366 GO:0034199 biological process activation of protein kinase A activity Any process that initiates the activity of the inactive enzyme protein kinase A. (more detail) 8 NA Homo sapiens

GOA TAX030293 GO:0090037 biological process positive regulation of protein kinase C signaling Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the (more detail) 8 NA Homo sapiens

GOA TAX030364 GO:0090154 biological process positive regulation of sphingolipid biosynthetic process Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid (more detail) 8 NA Homo sapiens

GOA TAX023139 GO:0035883 biological process enteroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or function (more detail) 8 NA Homo sapiens

GOA TAX018204 GO:0010898 biological process positive regulation of triglyceride catabolic process Any process that increases the frequency, rate, or extent of the chemical reactions and pathways res (more detail) 8 NA Homo sapiens

GOA TAX030411 GO:0090209 biological process negative regulation of triglyceride metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 8 NA Homo sapiens

GOA TAX018054 GO:0010700 biological process negative regulation of norepinephrine secretion Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. (more detail) 8 NA Homo sapiens

GOA TAX018073 GO:0010727 biological process negative regulation of hydrogen peroxide metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 8 NA Homo sapiens

GOA TAX024723 GO:0044387 biological process negative regulation of protein kinase activity by regulation of protein phosphorylation The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a (more detail) 8 NA Homo sapiens

GOA TAX025103 GO:0045416 biological process positive regulation of interleukin 8 biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 8 NA Homo sapiens

GOA TAX026761 GO:0051045 biological process negative regulation of membrane protein ectodomain proteolysis Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectod (more detail) 8 NA Homo sapiens

GOA TAX020667 GO:0030853 biological process negative regulation of granulocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differenti (more detail) 8 NA Homo sapiens

GOA TAX025166 GO:0045607 biological process regulation of inner ear auditory receptor cell differentiation Any process that modulates the frequency, rate or extent of auditory hair cell differentiation. (more detail) 8 NA Homo sapiens

GOA TAX020398 GO:0030235 molecular function nitric oxide synthase regulator activity Modulates the activity of nitric oxide synthase. (more detail) 8 NA Homo sapiens

GOA TAX031917 GO:1900364 biological process negative regulation of mRNA polyadenylation Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation. (more detail) 8 NA Homo sapiens

GOA TAX034931 GO:2000794 biological process regulation of epithelial cell proliferation involved in lung morphogenesis Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved i (more detail) 8 NA Homo sapiens

GOA IEI009818 Protein protein interactors of human gene PGM3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PGM3 (SwissProt ID=O (more detail) 8 17535438 Homo sapiens

I2D IEI015828 Protein protein interactors of human gene ZNRF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNRF3 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI010870 Protein protein interactors of human gene RAB30 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAB30 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI004385 Protein protein interactors of human gene F11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene F11 (SwissProt ID=P0 (more detail) 8 17535438 Homo sapiens

I2D IEI004730 Protein protein interactors of human gene FGD6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FGD6 (SwissProt ID=Q (more detail) 8 17535438 Homo sapiens

I2D IEI005600 Protein protein interactors of human gene GTPBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTPBP2 (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D IEI014219 Protein protein interactors of human gene TRIM14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM14 (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D IEI001566 Protein protein interactors of human gene C1R from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C1R (SwissProt ID=P0 (more detail) 8 17535438 Homo sapiens

I2D TAX035002 GO:2001012 biological process mesenchymal cell differentiation involved in renal system development The process in which relatively unspecialized cells acquire specialized structural and/or functional (more detail) 8 NA Homo sapiens

GOA TAX028280 GO:0061052 biological process negative regulation of cell growth involved in cardiac muscle cell development Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, wh (more detail) 8 NA Homo sapiens

GOA TAX029815 GO:0072075 biological process metanephric mesenchyme development The biological process whose specific outcome is the progression of a metanephric mesenchyme from an (more detail) 8 NA Homo sapiens

GOA TAX029862 GO:0072161 biological process mesenchymal cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional (more detail) 8 NA Homo sapiens

GOA TAX027613 GO:0060020 biological process Bergmann glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, spec (more detail) 8 NA Homo sapiens

GOA TAX033579 GO:1904714 biological process regulation of chaperone mediated autophagy Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy. (more detail) 8 NA Homo sapiens

GOA TAX034434 GO:2000020 biological process positive regulation of male gonad development Any process that activates or increases the frequency, rate or extent of male gonad development. (more detail) 8 NA Homo sapiens

GOA TAX033828 GO:1905216 biological process positive regulation of RNA binding Any process that activates or increases the frequency, rate or extent of RNA binding. (more detail) 8 NA Homo sapiens

GOA IEI009053 Protein protein interactors of human gene NRG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NRG1 (SwissProt ID=Q (more detail) 8 17535438 Homo sapiens

I2D IEI002836 Protein protein interactors of human gene COMMD7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD7 (SwissProt ID (more detail) 8 17535438 Homo sapiens

I2D IEI002933 Protein protein interactors of human gene CPOX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CPOX (SwissProt ID=P (more detail) 8 17535438 Homo sapiens

I2D IEI011649 Protein protein interactors of human gene RSAD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RSAD2 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI011770 Protein protein interactors of human gene SALL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SALL1 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI005132 Protein protein interactors of human gene GDF5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GDF5 (SwissProt ID=P (more detail) 8 17535438 Homo sapiens

I2D IEI005272 Protein protein interactors of human gene GLUD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLUD2 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI013377 Protein protein interactors of human gene TAOK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAOK3 (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D IEI008022 Protein protein interactors of human gene MKX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MKX (SwissProt ID=Q8 (more detail) 8 17535438 Homo sapiens

I2D IEI008479 Protein protein interactors of human gene MYO3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYO3B (SwissProt ID= (more detail) 8 17535438 Homo sapiens

I2D TAX030127 GO:0072710 biological process response to hydroxyurea Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 8 NA Homo sapiens

GOA MOX000986 Genes associated with Computational Drug Signature Echinocystic acid Genes associated with Computational Drug Signature Echinocystic acid, curated by the Drug Signature (more detail) 8 25990557 Homo sapiens

DSigDB MOX000603 Genes associated with Computational Drug Signature phytosphingosine Genes associated with Computational Drug Signature phytosphingosine, curated by the Drug Signature D (more detail) 8 25990557 Homo sapiens

DSigDB MOX004955 Genes associated with Computational Drug Signature trimetrexate Genes associated with Computational Drug Signature trimetrexate, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens

DSigDB TAX014761 GO:0003689 molecular function DNA clamp loader activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure o (more detail) 8 NA Homo sapiens

GOA GEX001581 thyroid cancer thyroid cancer associated genes. PAGER constructed this gene set by grouping all genes which are ass (more detail) 8 NA Homo sapiens

GAD MAX002910 Examples of transcription factors whose activities are regulated by MAPK7 [GeneID=5598] phosphorylation. The mitogen-activated protein kinases (MAPKs) are a family of serine/threonine kinases that play an (more detail) 8 NA Homo sapiens

MSigDB MEX000217 Genes associated with Approved Drug metoclopramide Genes associated with Approved Drug metoclopramide, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens

DSigDB MEX002316 Genes associated with Kinase Inhibitor GW693917A Genes associated with Kinase Inhibitor GW693917A, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens

DSigDB MOX004028 Genes associated with Computational Drug Signature Pentetic acid Genes associated with Computational Drug Signature Pentetic acid, curated by the Drug Signature Data (more detail) 8 25990557 Homo sapiens

DSigDB MOX003586 Genes associated with Computational Drug Signature 1,4 Pentadien 3 one, 1,5 bis(2,3 dimethoxyphenyl) , (1E,4E) Genes associated with Computational Drug Signature 1,4-Pentadien-3-one, 1,5-bis(2,3-dimethoxyphenyl) (more detail) 8 25990557 Homo sapiens

DSigDB MOX002811 Genes associated with Computational Drug Signature DIHEPTYL PHTHALATE Genes associated with Computational Drug Signature DIHEPTYL PHTHALATE, curated by the Drug Signature (more detail) 8 25990557 Homo sapiens

DSigDB GEX167730 Male pattern baldness Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association (more detail) 8 22693459 Homo sapiens

GWAS Catalog TAX013630 GO:0001164 molecular function RNA polymerase I CORE element sequence specific DNA binding Interacting selectively and non-covalently with the regulatory region composed of the transcription (more detail) 8 NA Homo sapiens

GOA PEX001907 ARID: ARID/BRIGHT DNA binding domain This domain is know as ARID for AT-Rich Interaction Domain 1, and also known as the BRIGHT domain 3. (more detail) 8 NA Homo sapiens

Pfam TAX013587 GO:0001013 molecular function RNA polymerase I regulatory region DNA binding Interacting selectively and non-covalently with a DNA region that controls the transcription of a re (more detail) 8 NA Homo sapiens

GOA TAX015578 GO:0005078 molecular function MAP kinase scaffold activity The binding activity of a molecule that functions as a physical support for the assembly of a multip (more detail) 8 NA Homo sapiens

GOA MOX014852 Genes associated with Computational Drug Signature ro 32 0432 Genes associated with Computational Drug Signature ro 32-0432, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens

DSigDB FEX003291 Testicular Duale07 9genes Table 3: List of apoptosis-related genes (n = 24). 15 up-regulated and 9 down-regulated genes in TGC (more detail) 8 17711579 Homo sapiens

GeneSigDB FAX000103 Targets of MicroRNA CGTCTTA,MIR 208 (more detail) 8 NA Homo sapiens

MSigDB FEX002605 Prostate Haudenschild04 9genes Table 3a. Cell cycle and Id proteins up-regulated by BMP-6 (more detail) 8 15548695 Homo sapiens

GeneSigDB MAX002911 Examples of transcription factors whose activities are regulated by MAPK8 and MAPK9 [GeneID=5599;5601]. The mitogen-activated protein kinases (MAPKs) are a family of serine/threonine kinases that play an (more detail) 8 NA Homo sapiens

MSigDB MEX001627 Genes associated with Kinase Inhibitor GW770249X Genes associated with Kinase Inhibitor GW770249X, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens

DSigDB MEX000177 Genes associated with Approved Drug isoproterenol Genes associated with Approved Drug isoproterenol, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens

DSigDB MOX002219 Genes associated with Computational Drug Signature Fosbretabulin Genes associated with Computational Drug Signature Fosbretabulin, curated by the Drug Signature Data (more detail) 8 25990557 Homo sapiens

DSigDB MOX002297 Genes associated with Computational Drug Signature Dexanabinol Genes associated with Computational Drug Signature Dexanabinol, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens

DSigDB TAX017020 GO:0008024 cellular component cyclin/CDK positive transcription elongation factor complex A transcription elongation factor complex that facilitates the transition from abortive to productiv (more detail) 8 NA Homo sapiens

GOA TAX013628 GO:0001162 molecular function RNA polymerase II intronic transcription regulatory region sequence specific DNA binding Interacting selectively and non-covalently with an RNA polymerase II intronic DNA sequence that regu (more detail) 8 NA Homo sapiens

GOA TAX013418 GO:0000439 cellular component core TFIIH complex The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or (more detail) 8 NA Homo sapiens

GOA WAG000016 rho selective guanine exchange factor akap13 mediates stress fiber formation The A-kise anchor protein 13 (AKAP13, also known as AKAP-LBC) is one of a group of structurally dive (more detail) 8 NA Homo sapiens

BioCarta MAX002292 Genes down regulated in Calu 6 cells (lung cancer) at 1 h time point after TNF [GeneID=7124] treatment. p38 mitogen-activated protein kinase (MAPK) is rapidly activated by stresses and is believed to play (more detail) 8 NA Homo sapiens

MSigDB MEX001547 Genes associated with Kinase Inhibitor 732983 37 8 Genes associated with Kinase Inhibitor 732983-37-8, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens

DSigDB MOX003609 Genes associated with Computational Drug Signature temephos Genes associated with Computational Drug Signature temephos, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens

DSigDB TAX016709 GO:0006975 biological process DNA damage induced protein phosphorylation The widespread phosphorylation of various molecules, triggering many downstream processes, that occu (more detail) 8 NA Homo sapiens

GOA TAX013668 GO:0001514 biological process selenocysteine incorporation The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codo (more detail) 8 NA Homo sapiens

GOA MOX011633 Genes associated with Computational Drug Signature CHEMBL608532 Genes associated with Computational Drug Signature CHEMBL608532, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens

DSigDB MAX000871 Genes down regulated in A549 cells (lung cancer) after treatment with AZD0530 [PubChem=10302451], a SRC [GeneID=6714] kinase inhibitor. Deregulated activation of the Src tyrosine kinase and heightened Id1 expression are independent medi (more detail) 8 NA Homo sapiens

MSigDB WIG001449 Circadian Clock in Mammals Circadian Clock in Mammals (more detail) 8 NA Homo sapiens

Protein Lounge MAX003296 Selected genes up regulated in DU145 and PC 3 cells (prostate cancer) after treatment with the NSAID (non steroid anti inflammatory drug) sulindac [PubChem=5352]. Numerous studies show that nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in chemopreve (more detail) 8 NA Homo sapiens

MSigDB MEX001406 Genes associated with Kinase Inhibitor CHEMBL1967720 Genes associated with Kinase Inhibitor CHEMBL1967720, curated by the Drug Signature Database (DSigDB (more detail) 8 25990557 Homo sapiens

DSigDB MEX001609 Genes associated with Kinase Inhibitor 2zv2 Genes associated with Kinase Inhibitor 2zv2, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens

DSigDB MOX004521 Genes associated with Computational Drug Signature phloroglucinol Genes associated with Computational Drug Signature phloroglucinol, curated by the Drug Signature Dat (more detail) 8 25990557 Homo sapiens

DSigDB MOX002859 Genes associated with Computational Drug Signature DETA NONOate Genes associated with Computational Drug Signature DETA NONOate, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens

DSigDB MOX002291 Genes associated with Computational Drug Signature Suillin Genes associated with Computational Drug Signature Suillin, curated by the Drug Signature Database ( (more detail) 8 25990557 Homo sapiens

DSigDB PEX002016 JmjN: jmjN domain (more detail) 8 NA Homo sapiens

Pfam PEX002086 zf CXXC: CXXC zinc finger domain This domain contains eight conserved cysteine residues that bind to two zinc ions. The CXXC domain (more detail) 8 NA Homo sapiens

Pfam WAG001284 AKT phosphorylates targets in the cytosol (more detail) 8 NA Homo sapiens

Reactome MAX001228 Prmary innate immune response genes induced in 293T cells (embryonic kidney) by overexpression of STING (TMEM173) [GeneID=340061]. The cellular innate immune system is essential for recognizing pathogen infection and for establishi (more detail) 8 NA Homo sapiens

MSigDB MAX002807 Genes significantly mutated in 91 glioblastoma samples. Human cancer cells typically harbour multiple chromosomal aberrations, nucleotide substitutions and (more detail) 8 NA Homo sapiens

MSigDB MEX001920 Genes associated with Kinase Inhibitor GW784307A Genes associated with Kinase Inhibitor GW784307A, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens

DSigDB MOX000475 Genes associated with Computational Drug Signature Trilostane Genes associated with Computational Drug Signature Trilostane, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens

DSigDB MOX003053 Genes associated with Computational Drug Signature Platycodin D Genes associated with Computational Drug Signature Platycodin D, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens

DSigDB MOX002372 Genes associated with Computational Drug Signature S Allylcysteine Genes associated with Computational Drug Signature S-Allylcysteine, curated by the Drug Signature Da (more detail) 8 25990557 Homo sapiens

DSigDB MOX009479 Genes associated with Computational Drug Signature CHEMBL292495 Genes associated with Computational Drug Signature CHEMBL292495, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens

DSigDB TAX016342 GO:0006449 biological process regulation of translational termination Any process that modulates the frequency, rate or extent of translational termination. (more detail) 8 NA Homo sapiens

GOA TAX017947 GO:0010511 biological process regulation of phosphatidylinositol biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 8 NA Homo sapiens

GOA TAX014705 GO:0003337 biological process mesenchymal to epithelial transition involved in metanephros morphogenesis A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular ad (more detail) 8 NA Homo sapiens

GOA PEX001018 MBT: mbt repeat The function of this repeat is unknown, but is found in a number of nuclear proteins such as drosoph (more detail) 8 NA Homo sapiens

Pfam MOX014671 Genes associated with Computational Drug Signature Purvalanol B Genes associated with Computational Drug Signature Purvalanol B, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens

DSigDB MAX002393 G1 to S phase regulators significantly changed in DanG cells (pancreatic cancer) treated with Ly294002 [PubChem=3973], a phosphoinositide 3 kinase (PI3K) inhibitor. The phosphoinositide-3-kinase (PI3K)/AKT signaling pathway controls fundamental processes of cancer (more detail) 8 NA Homo sapiens

MSigDB MEX001338 Genes associated with Kinase Inhibitor 5Z 7 Oxozeaenol Genes associated with Kinase Inhibitor 5Z-7-Oxozeaenol, curated by the Drug Signature Database (DSig (more detail) 8 25990557 Homo sapiens

DSigDB MOX001807 Genes associated with Computational Drug Signature Sappanchalcone Genes associated with Computational Drug Signature Sappanchalcone, curated by the Drug Signature Dat (more detail) 8 25990557 Homo sapiens

DSigDB MOX000685 Genes associated with Computational Drug Signature 2,3,7,8 TETRACHLORODIBENZOFURAN Genes associated with Computational Drug Signature 2,3,7,8-TETRACHLORODIBENZOFURAN, curated by the D (more detail) 8 25990557 Homo sapiens

DSigDB MOX013207 Genes associated with Computational Drug Signature isoproterenol Genes associated with Computational Drug Signature isoproterenol, curated by the Drug Signature Data (more detail) 8 25990557 Homo sapiens

DSigDB TAX016344 GO:0006451 biological process translational readthrough The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the (more detail) 8 NA Homo sapiens

GOA TAX017085 GO:0008140 molecular function cAMP response element binding protein binding Interacting selectively and non-covalently with a cAMP response element binding protein (a CREB prot (more detail) 8 NA Homo sapiens

GOA TAX017946 GO:0010510 biological process regulation of acetyl CoA biosynthetic process from pyruvate Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 8 NA Homo sapiens

GOA TAX013298 GO:0000183 biological process chromatin silencing at rDNA Repression of transcription of ribosomal DNA by altering the structure of chromatin. (more detail) 8 NA Homo sapiens

GOA MEX001241 Genes associated with Kinase Inhibitor Kinome 77 Genes associated with Kinase Inhibitor Kinome_77, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens

DSigDB MEX001462 Genes associated with Kinase Inhibitor SU9516 Genes associated with Kinase Inhibitor SU9516, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens

DSigDB MOX004673 Genes associated with Computational Drug Signature D Sorbitol Genes associated with Computational Drug Signature D-Sorbitol, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens

DSigDB TAX013629 GO:0001163 molecular function RNA polymerase I regulatory region sequence specific DNA binding Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulat (more detail) 8 NA Homo sapiens

GOA MOX015639 Genes associated with Computational Drug Signature Triphenylacrylonitrile Genes associated with Computational Drug Signature Triphenylacrylonitrile, curated by the Drug Signa (more detail) 8 25990557 Homo sapiens

DSigDB WAG000838 sodd/tnfr1 signaling pathway The tumor necrosis factor (TNF) receptor superfamily contains several members with homologous cytopl (more detail) 8 NA Homo sapiens

BioCarta MAX000308 Genes for which mutations result in developmental defects in the great vessels formation and valvulogenesis, a major class of congenital heart disease. Congenital heart disease is the leading cause of infant morbidity in the Western world, but only in (more detail) 8 NA Homo sapiens

MSigDB MEX002351 Genes associated with Kinase Inhibitor 406209 26 5 Genes associated with Kinase Inhibitor 406209-26-5, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens

DSigDB IEI001568 Protein protein interactors of human gene C1S from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C1S (SwissProt ID=P0 (more detail) 10 17535438 Homo sapiens

I2D IEI008134 Protein protein interactors of human gene MPL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MPL (SwissProt ID=P4 (more detail) 10 17535438 Homo sapiens

I2D IEI002159 Protein protein interactors of human gene CD83 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CD83 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI004489 Protein protein interactors of human gene FAM189A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM189A2 (SwissProt (more detail) 10 17535438 Homo sapiens

I2D IEI011841 Protein protein interactors of human gene SCD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCD (SwissProt ID=O0 (more detail) 10 17535438 Homo sapiens

I2D IEI006817 Protein protein interactors of human gene KIF13B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIF13B (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D TAX021476 GO:0032356 molecular function oxidized DNA binding Interacting selectively and non-covalently with oxidized residues in DNA. (more detail) 10 NA Homo sapiens

GOA TAX028906 GO:0070391 biological process response to lipoteichoic acid Any process that results in a change in state or activity of an organism (in terms of movement, secr (more detail) 10 NA Homo sapiens

GOA TAX023677 GO:0042118 biological process endothelial cell activation The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, (more detail) 10 NA Homo sapiens

GOA TAX028957 GO:0070486 biological process leukocyte aggregation The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules. (more detail) 10 NA Homo sapiens

GOA TAX028973 GO:0070513 molecular function death domain binding Interacting selectively and non-covalently with a death domain of a protein. The death domain (DD) i (more detail) 10 NA Homo sapiens

GOA TAX029329 GO:0071223 biological process cellular response to lipoteichoic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 10 NA Homo sapiens

GOA TAX024165 GO:0043121 molecular function neurotrophin binding Interacting selectively and non-covalently with a neurotrophin, any of a family of growth factors th (more detail) 10 NA Homo sapiens

GOA TAX018955 GO:0016281 cellular component eukaryotic translation initiation factor 4F complex The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is (more detail) 10 NA Homo sapiens

GOA TAX022333 GO:0034139 biological process regulation of toll like receptor 3 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway. (more detail) 10 NA Homo sapiens

GOA TAX027677 GO:0060100 biological process positive regulation of phagocytosis, engulfment Any process that activates or increases the frequency, rate or extent of the internalization of bact (more detail) 10 NA Homo sapiens

GOA TAX025195 GO:0045647 biological process negative regulation of erythrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differenti (more detail) 10 NA Homo sapiens

GOA TAX020558 GO:0030546 molecular function receptor activator activity The function of interacting (directly or indirectly) with receptors such that the proportion of rece (more detail) 10 NA Homo sapiens

GOA TAX028102 GO:0060736 biological process prostate gland growth The increase in size or mass of the prostate gland where the increase in size or mass has the specif (more detail) 10 NA Homo sapiens

GOA TAX023595 GO:0039706 molecular function co receptor binding Interacting selectively and non-covalently with a coreceptor. A coreceptor acts in cooperation with (more detail) 10 NA Homo sapiens

GOA TAX028879 GO:0070344 biological process regulation of fat cell proliferation Any process that modulates the frequency, rate or extent of fat cell proliferation. (more detail) 10 NA Homo sapiens

GOA TAX026325 GO:0048742 biological process regulation of skeletal muscle fiber development Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscl (more detail) 10 NA Homo sapiens

GOA TAX028444 GO:0061469 biological process regulation of type B pancreatic cell proliferation Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation. (more detail) 10 NA Homo sapiens

GOA TAX020737 GO:0030957 molecular function Tat protein binding Interacting selectively and non-covalently with Tat, a viral transactivating regulatory protein from (more detail) 10 NA Homo sapiens

GOA IEI009222 Protein protein interactors of human gene OAZ3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OAZ3 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI003418 Protein protein interactors of human gene DDX31 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX31 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI003744 Protein protein interactors of human gene DPF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DPF1 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI008574 Protein protein interactors of human gene NARF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NARF (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI002567 Protein protein interactors of human gene CISD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CISD1 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI004118 Protein protein interactors of human gene ELP5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELP5 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI004439 Protein protein interactors of human gene FAM117B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM117B (SwissProt I (more detail) 10 17535438 Homo sapiens

I2D IEI011896 Protein protein interactors of human gene SDAD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SDAD1 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI005859 Protein protein interactors of human gene HIVEP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HIVEP3 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI001280 Protein protein interactors of human gene BCL2L10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCL2L10 (SwissProt I (more detail) 10 17535438 Homo sapiens

I2D IEI001835 Protein protein interactors of human gene CASZ1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASZ1 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI002317 Protein protein interactors of human gene CELF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CELF2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI004377 Protein protein interactors of human gene EYA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EYA2 (SwissProt ID=O (more detail) 10 17535438 Homo sapiens

I2D IEI012965 Protein protein interactors of human gene SRFBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRFBP1 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI006630 Protein protein interactors of human gene KAT14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KAT14 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI000593 Protein protein interactors of human gene ANKRD12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANKRD12 (SwissProt I (more detail) 10 17535438 Homo sapiens

I2D IEI014424 Protein protein interactors of human gene TTC32 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTC32 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI008515 Protein protein interactors of human gene N4BP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene N4BP2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI010456 Protein protein interactors of human gene PREX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PREX1 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI004203 Protein protein interactors of human gene EPHA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPHA1 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI013578 Protein protein interactors of human gene TET2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TET2 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI014826 Protein protein interactors of human gene UVSSA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UVSSA (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI001629 Protein protein interactors of human gene C5AR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C5AR1 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D TAX017814 GO:0009950 biological process dorsal/ventral axis specification The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis i (more detail) 10 NA Homo sapiens

GOA TAX021590 GO:0032486 biological process Rap protein signal transduction A series of molecular signals within the cell that are mediated by a member of the Rap family of pro (more detail) 10 NA Homo sapiens

GOA TAX021291 GO:0032025 biological process response to cobalt ion Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 10 NA Homo sapiens

GOA TAX026371 GO:0048853 biological process forebrain morphogenesis The process in which the anatomical structures of the forebrain are generated and organized. The for (more detail) 10 NA Homo sapiens

GOA TAX033802 GO:1905155 biological process positive regulation of membrane invagination Any process that activates or increases the frequency, rate or extent of membrane invagination. (more detail) 10 NA Homo sapiens

GOA IEI008542 Protein protein interactors of human gene NACC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NACC2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI002838 Protein protein interactors of human gene COMMD9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD9 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI003578 Protein protein interactors of human gene DKK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DKK3 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI003835 Protein protein interactors of human gene DUSP11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP11 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D TAX021856 GO:0032908 biological process regulation of transforming growth factor beta1 production Any process that modulates the frequency, rate, or extent of production of transforming growth facto (more detail) 10 NA Homo sapiens

GOA TAX033133 GO:1903789 biological process regulation of amino acid transmembrane transport Any process that modulates the frequency, rate or extent of amino acid transmembrane transport. (more detail) 10 NA Homo sapiens

GOA IEI002035 Protein protein interactors of human gene CCNB1IP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNB1IP1 (SwissProt (more detail) 10 17535438 Homo sapiens

I2D IEI000518 Protein protein interactors of human gene ALS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ALS2 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI014226 Protein protein interactors of human gene TRIM22 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM22 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI011824 Protein protein interactors of human gene SCAF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCAF8 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI012230 Protein protein interactors of human gene SIPA1L3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIPA1L3 (SwissProt I (more detail) 10 17535438 Homo sapiens

I2D IEI006287 Protein protein interactors of human gene IKZF5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IKZF5 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI014212 Protein protein interactors of human gene TRIB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIB1 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI000884 Protein protein interactors of human gene ARL5A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARL5A (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D TAX022130 GO:0033523 biological process histone H2B ubiquitination The modification of histone H2B by addition of ubiquitin groups. (more detail) 10 NA Homo sapiens

GOA TAX031001 GO:0098505 molecular function G rich strand telomeric DNA binding Interacting selectively and non-covalently with G-rich, single-stranded, telomere-associated DNA. (more detail) 10 NA Homo sapiens

GOA IEI014504 Protein protein interactors of human gene TWIST2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TWIST2 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI014505 Protein protein interactors of human gene TWNK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TWNK (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI001338 Protein protein interactors of human gene BICRA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BICRA (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI001636 Protein protein interactors of human gene C6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C6 (SwissProt ID=P13 (more detail) 10 17535438 Homo sapiens

I2D TAX021872 GO:0032926 biological process negative regulation of activin receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any ac (more detail) 10 NA Homo sapiens

GOA TAX033186 GO:1903897 biological process regulation of PERK mediated unfolded protein response Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein respo (more detail) 10 NA Homo sapiens

GOA TAX034482 GO:2000109 biological process regulation of macrophage apoptotic process Any process that modulates the frequency, rate or extent of macrophage apoptotic process. (more detail) 10 NA Homo sapiens

GOA IEI002054 Protein protein interactors of human gene CCNL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNL2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI008592 Protein protein interactors of human gene NBEA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NBEA (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI006201 Protein protein interactors of human gene IFNL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFNL3 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI006635 Protein protein interactors of human gene KAT6B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KAT6B (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI013565 Protein protein interactors of human gene TEP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TEP1 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI015015 Protein protein interactors of human gene WDR5B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR5B (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI002469 Protein protein interactors of human gene CHD9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD9 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI002742 Protein protein interactors of human gene CNPY2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNPY2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI009511 Protein protein interactors of human gene PARP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PARP4 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI004196 Protein protein interactors of human gene EPB41L5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPB41L5 (SwissProt I (more detail) 10 17535438 Homo sapiens

I2D IEI004951 Protein protein interactors of human gene FUT7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FUT7 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI005763 Protein protein interactors of human gene HDGFL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDGFL2 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D TAX017991 GO:0010603 biological process regulation of cytoplasmic mRNA processing body assembly Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bondin (more detail) 10 NA Homo sapiens

GOA WIG000662 Genes involved in Activation of Chaperone Genes by ATF6 alpha (more detail) 10 NA Homo sapiens

MSigDB MOX003273 Genes associated with Computational Drug Signature nu2058 Genes associated with Computational Drug Signature nu2058, curated by the Drug Signature Database (D (more detail) 10 25990557 Homo sapiens

DSigDB MOX012803 Genes associated with Computational Drug Signature gamma Imino ATP Genes associated with Computational Drug Signature gamma-Imino-ATP, curated by the Drug Signature Da (more detail) 10 25990557 Homo sapiens

DSigDB TAX014153 GO:0002281 biological process macrophage activation involved in immune response A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine (more detail) 10 NA Homo sapiens

GOA MOX016606 Genes associated with Computational Drug Signature deferiprone Genes associated with Computational Drug Signature deferiprone, curated by the Drug Signature Databa (more detail) 10 25990557 Homo sapiens

DSigDB WIG001283 Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (more detail) 10 NA Homo sapiens

MSigDB MEX002075 Genes associated with Kinase Inhibitor 1 [4 (4 aminothieno[2,3 d]pyrimidin 5 yl)phenyl] 3 (3 methylphenyl)urea Genes associated with Kinase Inhibitor 1-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-(3-methylp (more detail) 10 25990557 Homo sapiens

DSigDB WIG000425 Double Stranded RNA Induced Gene Expression One defense against viral infection is provided by PKR, double-stranded RNA activated protein kinase (more detail) 10 NA Homo sapiens

MSigDB MOX001696 Genes associated with Computational Drug Signature TRIMETHYLTIN CHLORIDE Genes associated with Computational Drug Signature TRIMETHYLTIN CHLORIDE, curated by the Drug Signat (more detail) 10 25990557 Homo sapiens

DSigDB MOX000443 Genes associated with Computational Drug Signature 2,3,4,5 TETRACHLOROPHENOL Genes associated with Computational Drug Signature 2,3,4,5-TETRACHLOROPHENOL, curated by the Drug Si (more detail) 10 25990557 Homo sapiens

DSigDB MOX003328 Genes associated with Computational Drug Signature Procyanidin B2 Genes associated with Computational Drug Signature Procyanidin B2, curated by the Drug Signature Dat (more detail) 10 25990557 Homo sapiens

DSigDB TAX000228 Genes annotated by the GO term GO:0016458. Any mechanism, at the level of transcription or post transcription, causing long term gene inactivation. (more detail) 10 NA Homo sapiens

MSigDB TAX000608 Genes annotated by the GO term GO:0033044. Any process that modulates the frequency, rate or extent of the processes involved in the formation, arrangement of constituent parts, or disassembly of a chromosome. (more detail) 10 NA Homo sapiens

MSigDB WIG001959 Wnt Signaling Pathway Wnt Signaling Pathway (more detail) 10 NA Homo sapiens

WikiPathway GEX167639 Parkinson's disease Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. (more detail) 10 22451204 Homo sapiens

GWAS Catalog MOX012267 Genes associated with Computational Drug Signature Diacerein Genes associated with Computational Drug Signature Diacerein, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB MOX015423 Genes associated with Computational Drug Signature Tanespimycin Genes associated with Computational Drug Signature Tanespimycin, curated by the Drug Signature Datab (more detail) 10 25990557 Homo sapiens

DSigDB TAX014333 GO:0002638 biological process negative regulation of immunoglobulin production Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin produc (more detail) 10 NA Homo sapiens

GOA FEX002204 Lymphoma Martinez03 15genes BlastedVariant (B) Figure 3b Gene expression signature for mutated blasted variant (B) (more detail) 10 14678979 Homo sapiens

GeneSigDB GEX000015 acute coronary syndrome acute coronary syndrome associated genes. PAGER constructed this gene set by grouping all genes whic (more detail) 10 NA Homo sapiens

GAD TAX001209 Genes annotated by the GO term GO:0005159. Interacting selectively with the insulin like growth factor receptor. (more detail) 10 NA Homo sapiens

MSigDB TAX000199 Genes annotated by the GO term GO:0001837. A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. (more detail) 10 NA Homo sapiens

MSigDB WIG000134 Signaling mediated by p38 gamma and p38 delta (more detail) 10 NA Homo sapiens

MSigDB MEX002245 Genes associated with Kinase Inhibitor Kinome 192 Genes associated with Kinase Inhibitor Kinome_192, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MEX001679 Genes associated with Kinase Inhibitor Kinome 504 Genes associated with Kinase Inhibitor Kinome_504, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MEX002168 Genes associated with Kinase Inhibitor GW782612X Genes associated with Kinase Inhibitor GW782612X, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MOX008993 Genes associated with Computational Drug Signature CHEMBL230686 Genes associated with Computational Drug Signature CHEMBL230686, curated by the Drug Signature Datab (more detail) 10 25990557 Homo sapiens

DSigDB MOX000578 Genes associated with Computational Drug Signature Oridonin Genes associated with Computational Drug Signature Oridonin, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB TAX018417 GO:0014889 biological process muscle atrophy A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber di (more detail) 10 NA Homo sapiens

GOA TAX014568 GO:0003081 biological process regulation of systemic arterial blood pressure by renin angiotensin The process in which renin-angiotensin modulates the force with which blood passes through the circu (more detail) 10 NA Homo sapiens

GOA MOX017651 Genes associated with Computational Drug Signature Regorafenib Genes associated with Computational Drug Signature Regorafenib, curated by the Drug Signature Databa (more detail) 10 25990557 Homo sapiens

DSigDB WAG000665 Signaling mediated by p38 gamma and p38 delta (more detail) 10 NA Homo sapiens

NCI-Nature Curated TAX000219 Genes annotated by the GO term GO:0048041. Establishment and maturation of focal adhesions, complexes of intracellular signaling and structural proteins which provide a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity. (more detail) 10 NA Homo sapiens

MSigDB TAX001188 Genes annotated by the GO term GO:0042054. Catalysis of the transfer of a methyl group (CH3 ) to a histone. (more detail) 10 NA Homo sapiens

MSigDB WIG001063 Genes involved in PECAM1 interactions (more detail) 10 NA Homo sapiens

MSigDB MEX000741 Genes associated with Approved Drug fulvestrant Genes associated with Approved Drug fulvestrant, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MOX003628 Genes associated with Computational Drug Signature ACRYLONITRILE Genes associated with Computational Drug Signature ACRYLONITRILE, curated by the Drug Signature Data (more detail) 10 25990557 Homo sapiens

DSigDB TAX000776 Genes annotated by the GO term GO:0006801. The chemical reactions and pathways involving superoxide, the superoxide anion O2 (superoxide free radical), or any compound containing this species. (more detail) 10 NA Homo sapiens

MSigDB MAX003263 Transcription factors down regulated in LNCaP cells (prostate cancer) by expression of GR [GeneID=2908] off a lentiviral vector. Glucocorticoids are extensively used in combination chemotherapy of advanced prostate cancer (PC). L (more detail) 10 NA Homo sapiens

MSigDB MEX000759 Genes associated with Approved Drug imatinib mesylate Genes associated with Approved Drug imatinib mesylate, curated by the Drug Signature Database (DSigD (more detail) 10 25990557 Homo sapiens

DSigDB WAG000235 il 6 signaling pathway Interleukin-6 (IL-6) is a cytokine that provokes a broad range of cellular and physiological respons (more detail) 10 NA Homo sapiens

BioCarta WIG001122 Genes involved in RAF/MAP kinase cascade (more detail) 10 NA Homo sapiens

MSigDB MEX001588 Genes associated with Kinase Inhibitor AG F 35231 Genes associated with Kinase Inhibitor AG-F-35231, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MOX001096 Genes associated with Computational Drug Signature Azuprostat Genes associated with Computational Drug Signature Azuprostat, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB MOX005033 Genes associated with Computational Drug Signature Quinpirole dihydrochloride Genes associated with Computational Drug Signature Quinpirole dihydrochloride, curated by the Drug S (more detail) 10 25990557 Homo sapiens

DSigDB GEX167064 Vertical cup disc ratio A genome-wide association study of optic disc parameters. (more detail) 10 20548946 Homo sapiens

GWAS Catalog MOX012240 Genes associated with Computational Drug Signature Desloratadine Genes associated with Computational Drug Signature Desloratadine, curated by the Drug Signature Data (more detail) 10 25990557 Homo sapiens

DSigDB MOX004847 Genes associated with Computational Drug Signature Lutein Genes associated with Computational Drug Signature Lutein, curated by the Drug Signature Database (D (more detail) 10 25990557 Homo sapiens

DSigDB MOX002958 Genes associated with Computational Drug Signature nitroaspirin Genes associated with Computational Drug Signature nitroaspirin, curated by the Drug Signature Datab (more detail) 10 25990557 Homo sapiens

DSigDB GEX166917 Mean corpuscular volume Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. (more detail) 16 19862010 Homo sapiens

GWAS Catalog MEX000196 Genes associated with Approved Drug mebendazole Genes associated with Approved Drug mebendazole, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB GEX001080 mean corpuscular volume mean corpuscular volume associated genes. PAGER constructed this gene set by grouping all genes whic (more detail) 16 NA Homo sapiens

GAD MOX001341 Genes associated with Computational Drug Signature PYRENE Genes associated with Computational Drug Signature PYRENE, curated by the Drug Signature Database (D (more detail) 16 25990557 Homo sapiens

DSigDB MOX016311 Genes associated with Computational Drug Signature METHYL METHANESULFONATE Genes associated with Computational Drug Signature METHYL METHANESULFONATE, curated by the Drug Sign (more detail) 16 25990557 Homo sapiens

DSigDB MOX000210 Genes associated with Computational Drug Signature Palmatine Genes associated with Computational Drug Signature Palmatine, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB GEX167293 Primary biliary cirrhosis Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. (more detail) 16 21399635 Homo sapiens

GWAS Catalog MOX017645 Genes associated with Computational Drug Signature 1,3,5 TRINITROBENZENE Genes associated with Computational Drug Signature 1,3,5-TRINITROBENZENE, curated by the Drug Signat (more detail) 16 25990557 Homo sapiens

DSigDB FEX001521 Leukemia Hamamura07 17genes Table 1. Identification of genes affected by bortezomib treatment; (b) Downregulated genes whose exp (more detail) 16 17895889 Homo sapiens

GeneSigDB MAX002847 Genes down regulated in SK NEP 1 cells (Wilm's tumor ) stably expressing inactivated forms of STAT1 [GeneID=6772] under growth stress (hypoxia or nutritional deprivation). Wilms' tumor (WT), one of the most common pediatric solid cancers, arises in the developing kidney a (more detail) 16 NA Homo sapiens

MSigDB MOX003253 Genes associated with Computational Drug Signature Fenhexamid Genes associated with Computational Drug Signature Fenhexamid, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens

DSigDB MOX004259 Genes associated with Computational Drug Signature levamisole Genes associated with Computational Drug Signature levamisole, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens

DSigDB MOX000590 Genes associated with Computational Drug Signature Mevastatin Genes associated with Computational Drug Signature Mevastatin, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens

DSigDB MOX013343 Genes associated with Computational Drug Signature L 741,626 Genes associated with Computational Drug Signature L-741,626, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB FEX002338 Lymphoma Germinal07 18genes Table S10. Gene expression values of the main regulatory network distinguishing ABC and GCB (more detail) 16 19455257 Homo sapiens

GeneSigDB MAX000664 Genes down regulated in HeLa cells upon knockdown of ELAVL1 [GeneID=1994] by RNAi. A high expression level of the beta-actin protein is required for important biological mechanisms, s (more detail) 16 NA Homo sapiens

MSigDB MEX001336 Genes associated with Kinase Inhibitor Kinome 2010 Genes associated with Kinase Inhibitor Kinome_2010, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB MOX004352 Genes associated with Computational Drug Signature N Methyl N nitrosourea Genes associated with Computational Drug Signature N-Methyl-N-nitrosourea, curated by the Drug Signa (more detail) 16 25990557 Homo sapiens

DSigDB FEX002017 LungNotCaner Kent08 Table 2. Fold change comparison between array and Q-PCR geometric means for 18 genes (more detail) 16 18358739 Homo sapiens

GeneSigDB FEX003478 Viral Zekri08 28genes Table 5: Up regulated gene symbols and related pathway. (more detail) 16 18959789 Homo sapiens

GeneSigDB MAX000762 Genes in the green cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. Breast cancer is a heterogeneous disease made of various molecular subtypes with different prognosis (more detail) 16 NA Homo sapiens

MSigDB MEX003410 Genes associated with Perturbagen Signature isoconazole Genes associated with Perturbagen Signature isoconazole, curated by the Drug Signature Database (DSi (more detail) 16 25990557 Homo sapiens

DSigDB MAX001542 Fig.5, Supplementary Fig.2 Genes overexpressed in human hepatocellular carcinoma with hepatoblast property The variability in the prognosis of individuals with hepatocellular carcinoma (HCC) suggests that HC (more detail) 16 NA Homo sapiens

MSigDB MAX003181 Genes down regulated by expression of HBV X protein (HBVgp3) [GeneID=944566] in primary hepatocytes. Hepatitis B virus (HBV) is a major risk factor for the development of hepatocellular carcinoma (HCC) (more detail) 16 NA Homo sapiens

MSigDB MOX001892 Genes associated with Computational Drug Signature Isorhamnetin Genes associated with Computational Drug Signature Isorhamnetin, curated by the Drug Signature Datab (more detail) 16 25990557 Homo sapiens

DSigDB MOX002326 Genes associated with Computational Drug Signature KN 62 Genes associated with Computational Drug Signature KN-62, curated by the Drug Signature Database (DS (more detail) 16 25990557 Homo sapiens

DSigDB TAX017214 GO:0008347 biological process glial cell migration The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintai (more detail) 16 NA Homo sapiens

GOA TAX017849 GO:0010042 biological process response to manganese ion Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 16 NA Homo sapiens

GOA MAX002760 High level amplifications detected in oral squamous cell carcinoma (OSCC) lines by array CGH analysis. Array-based comparative genomic hybridization (array-CGH) has good potential for the high-throughput (more detail) 16 NA Homo sapiens

MSigDB MEX001440 Genes associated with Kinase Inhibitor Kinome 866 Genes associated with Kinase Inhibitor Kinome_866, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB MOX001610 Genes associated with Computational Drug Signature PK 11195 Genes associated with Computational Drug Signature PK 11195, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB MOX015798 Genes associated with Computational Drug Signature Ursolic acid Genes associated with Computational Drug Signature Ursolic acid, curated by the Drug Signature Datab (more detail) 16 25990557 Homo sapiens

DSigDB TAX000127 Genes annotated by the GO term GO:0031497. The assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. (more detail) 16 NA Homo sapiens

MSigDB FEX000855 Colon Koehler04 18genes Table 3. Up-regulated transcripts with statistical significance in the high-stage group compared wit (more detail) 16 15307139 Homo sapiens

GeneSigDB TAX022003 GO:0033151 biological process V(D)J recombination The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specifi (more detail) 16 NA Homo sapiens

GOA IEI007673 Protein protein interactors of human gene MAP4K2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP4K2 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI001843 Protein protein interactors of human gene CAV2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAV2 (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D IEI000330 Protein protein interactors of human gene AEBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AEBP2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX030501 GO:0090335 biological process regulation of brown fat cell differentiation Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown f (more detail) 16 NA Homo sapiens

GOA TAX022183 GO:0033627 biological process cell adhesion mediated by integrin The attachment of a cell, either to another cell or to an underlying substrate such as the extracell (more detail) 16 NA Homo sapiens

GOA IEI011299 Protein protein interactors of human gene RHPN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RHPN2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI012253 Protein protein interactors of human gene SKAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SKAP1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI013388 Protein protein interactors of human gene TARS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TARS2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI000039 Protein protein interactors of human gene ABCB7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABCB7 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI008742 Protein protein interactors of human gene NELFA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NELFA (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI013639 Protein protein interactors of human gene TGM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TGM1 (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D IEI008884 Protein protein interactors of human gene NLRP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NLRP3 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI000430 Protein protein interactors of human gene AKAP5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKAP5 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI014262 Protein protein interactors of human gene TRIM56 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM56 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX029341 GO:0071243 biological process cellular response to arsenic containing substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 16 NA Homo sapiens

GOA IEI002044 Protein protein interactors of human gene CCNE2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNE2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI002751 Protein protein interactors of human gene CNTFR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNTFR (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI006599 Protein protein interactors of human gene JMJD1C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JMJD1C (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI015085 Protein protein interactors of human gene WSB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WSB1 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI009719 Protein protein interactors of human gene PDXDC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDXDC1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI003410 Protein protein interactors of human gene DDX19A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX19A (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI003600 Protein protein interactors of human gene DLX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLX2 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI006347 Protein protein interactors of human gene IL32 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL32 (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D TAX023740 GO:0042268 biological process regulation of cytolysis Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the lo (more detail) 16 NA Homo sapiens

GOA IEI004885 Protein protein interactors of human gene FOXP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXP2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI005091 Protein protein interactors of human gene GBA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GBA (SwissProt ID=P0 (more detail) 16 17535438 Homo sapiens

I2D IEI007262 Protein protein interactors of human gene LIG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LIG1 (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D TAX020531 GO:0030502 biological process negative regulation of bone mineralization Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization. (more detail) 16 NA Homo sapiens

GOA TAX028806 GO:0070227 biological process lymphocyte apoptotic process Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has th (more detail) 16 NA Homo sapiens

GOA TAX021922 GO:0033002 biological process muscle cell proliferation The expansion of a muscle cell population by cell division. (more detail) 16 NA Homo sapiens

GOA IEI003711 Protein protein interactors of human gene DNTTIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNTTIP1 (SwissProt I (more detail) 16 17535438 Homo sapiens

I2D TAX027245 GO:0051895 biological process negative regulation of focal adhesion assembly Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembl (more detail) 16 NA Homo sapiens

GOA TAX027013 GO:0051447 biological process negative regulation of meiotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the meiotic ce (more detail) 16 NA Homo sapiens

GOA TAX020039 GO:0021772 biological process olfactory bulb development The progression of the olfactory bulb over time from its initial formation until its mature state. T (more detail) 16 NA Homo sapiens

GOA IEI002278 Protein protein interactors of human gene CDKN2D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDKN2D (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI002803 Protein protein interactors of human gene COL3A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COL3A1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX024210 GO:0043186 cellular component P granule A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of m (more detail) 16 NA Homo sapiens

GOA TAX028474 GO:0061548 biological process ganglion development The process whose specific outcome is the progression of a ganglion over time, from its formation to (more detail) 14 NA Homo sapiens

GOA IEI001736 Protein protein interactors of human gene CALML3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CALML3 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI009977 Protein protein interactors of human gene PIWIL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIWIL4 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI012486 Protein protein interactors of human gene SLC4A1AP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC4A1AP (SwissProt (more detail) 14 17535438 Homo sapiens

I2D IEI006762 Protein protein interactors of human gene KDM4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM4B (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI011837 Protein protein interactors of human gene SCARB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCARB2 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI006862 Protein protein interactors of human gene KIR2DL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIR2DL4 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI013574 Protein protein interactors of human gene TESK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TESK1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI007411 Protein protein interactors of human gene LRRC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRRC1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX027767 GO:0060253 biological process negative regulation of glial cell proliferation Any process that stops or decreases the rate or extent of glial cell proliferation. (more detail) 14 NA Homo sapiens

GOA TAX021714 GO:0032688 biological process negative regulation of interferon beta production Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta produ (more detail) 14 NA Homo sapiens

GOA TAX033981 GO:1905564 biological process positive regulation of vascular endothelial cell proliferation Any process that activates or increases the frequency, rate or extent of vascular endothelial cell p (more detail) 14 NA Homo sapiens

GOA IEI015320 Protein protein interactors of human gene ZFP91 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZFP91 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI002172 Protein protein interactors of human gene CDC14B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC14B (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI002646 Protein protein interactors of human gene CLIC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLIC4 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI011282 Protein protein interactors of human gene RHOBTB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RHOBTB2 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI005100 Protein protein interactors of human gene GC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GC (SwissProt ID=P02 (more detail) 14 17535438 Homo sapiens

I2D IEI012278 Protein protein interactors of human gene SLC12A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC12A2 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI012572 Protein protein interactors of human gene SLTM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLTM (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI013127 Protein protein interactors of human gene STK36 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STK36 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI006484 Protein protein interactors of human gene IRF2BP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IRF2BP2 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI002193 Protein protein interactors of human gene CDC42EP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC42EP4 (SwissProt (more detail) 14 17535438 Homo sapiens

I2D IEI009454 Protein protein interactors of human gene PAIP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAIP2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI003423 Protein protein interactors of human gene DDX4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX4 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI011397 Protein protein interactors of human gene RNF144A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF144A (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI005392 Protein protein interactors of human gene GPATCH8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GPATCH8 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI005584 Protein protein interactors of human gene GTF2H3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2H3 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI000427 Protein protein interactors of human gene AKAP17A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKAP17A (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI007785 Protein protein interactors of human gene MCF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCF2 (SwissProt ID=P (more detail) 14 17535438 Homo sapiens

I2D IEI013280 Protein protein interactors of human gene SYNJ2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SYNJ2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI013962 Protein protein interactors of human gene TMF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TMF1 (SwissProt ID=P (more detail) 14 17535438 Homo sapiens

I2D TAX024114 GO:0043024 molecular function ribosomal small subunit binding Interacting selectively and non-covalently with any part of the small ribosomal subunit. (more detail) 14 NA Homo sapiens

GOA TAX022293 GO:0034063 biological process stress granule assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress gra (more detail) 14 NA Homo sapiens

GOA IEI008740 Protein protein interactors of human gene NEK8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEK8 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI009873 Protein protein interactors of human gene PHPT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHPT1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX024871 GO:0044849 biological process estrous cycle A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is (more detail) 14 NA Homo sapiens

GOA TAX025519 GO:0046325 biological process negative regulation of glucose import Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexo (more detail) 14 NA Homo sapiens

GOA IEI012190 Protein protein interactors of human gene SHOC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SHOC2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI007125 Protein protein interactors of human gene LAMB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LAMB2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI013761 Protein protein interactors of human gene TLR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLR1 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI014221 Protein protein interactors of human gene TRIM16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM16 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI014616 Protein protein interactors of human gene UBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBP1 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI011994 Protein protein interactors of human gene SENP8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SENP8 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI006919 Protein protein interactors of human gene KLHL15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHL15 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI009506 Protein protein interactors of human gene PARP14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PARP14 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D MOX004942 Genes associated with Computational Drug Signature ILOPROST Genes associated with Computational Drug Signature ILOPROST, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB MOX014988 Genes associated with Computational Drug Signature SB 206553 Genes associated with Computational Drug Signature SB 206553, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB MOX017720 Genes associated with Computational Drug Signature LEVOSIMENDAN Genes associated with Computational Drug Signature LEVOSIMENDAN, curated by the Drug Signature Datab (more detail) 14 25990557 Homo sapiens

DSigDB TAX014369 GO:0002689 biological process negative regulation of leukocyte chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis. (more detail) 14 NA Homo sapiens

GOA MOX016497 Genes associated with Computational Drug Signature 4,5,6,7 tetrabromobenzotriazole Genes associated with Computational Drug Signature 4,5,6,7-tetrabromobenzotriazole, curated by the D (more detail) 14 25990557 Homo sapiens

DSigDB WAG000214 apoptotic signaling in response to dna damage The cellular activation of the caspase cascade resulting in cell death is triggered by chemical dama (more detail) 14 NA Homo sapiens

BioCarta WAG000002 hypoxia inducible factor in the cardivascular system Hypoxia (or low O2 levels) affects various pathologies. First, tissue ischemia, a variation in O2 te (more detail) 14 NA Homo sapiens

BioCarta FEX003387 Viral Zhu03 14genes Table 1. Genes Induced in HCV Subgenomic RNA Replicon Cell Line FCA1 Cells (more detail) 14 12717400 Homo sapiens

GeneSigDB MEX002848 Genes associated with Perturbagen Signature chlorpropamide Genes associated with Perturbagen Signature chlorpropamide, curated by the Drug Signature Database ( (more detail) 14 25990557 Homo sapiens

DSigDB GEX000966 kidney transplant kidney transplant associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 14 NA Homo sapiens

GAD TAX000782 Genes annotated by the GO term GO:0051320. Progression through S phase, the part of the cell cycle during which DNA synthesis takes place. (more detail) 14 NA Homo sapiens

MSigDB MEX000108 Genes associated with Approved Drug doxazosin Genes associated with Approved Drug doxazosin, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX016003 Genes associated with Computational Drug Signature 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE Genes associated with Computational Drug Signature 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE, cu (more detail) 14 25990557 Homo sapiens

DSigDB MOX015812 Genes associated with Computational Drug Signature Valstar Genes associated with Computational Drug Signature Valstar, curated by the Drug Signature Database ( (more detail) 14 25990557 Homo sapiens

DSigDB TAX014571 GO:0003085 biological process negative regulation of systemic arterial blood pressure The process that reduces the force with which blood travels through the systemic arterial circulator (more detail) 14 NA Homo sapiens

GOA GOX001573 Genes regulated by the microRNA hsa miR 487b 3p using target scan (more detail) 14 NA Homo sapiens

TargetScan WAG001000 Dentatorubropallidoluysian atrophy (DRPLA) (more detail) 14 NA Homo sapiens

KEGG MAX001172 Down regulated genes constituting the molecular signature of Burkitt 's lymphoma. BACKGROUND: The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is unclear. (more detail) 14 NA Homo sapiens

MSigDB TAX000673 Genes annotated by the GO term GO:0032101. Any process that modulates the frequency, rate or extent of a response to an external stimulus. (more detail) 14 NA Homo sapiens

MSigDB MEX000971 Genes associated with Approved Drug acitretin Genes associated with Approved Drug acitretin, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002015 Genes associated with Kinase Inhibitor BS 181 Genes associated with Kinase Inhibitor BS-181, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX003700 Genes associated with Computational Drug Signature aspartame Genes associated with Computational Drug Signature aspartame, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB WIG001444 Checkpoint Comparative Pathways Checkpoint Comparative Pathways (more detail) 14 NA Homo sapiens

Protein Lounge MEX000451 Genes associated with Approved Drug hydralazine hydrochloride Genes associated with Approved Drug hydralazine hydrochloride, curated by the Drug Signature Databas (more detail) 14 25990557 Homo sapiens

DSigDB MEX001207 Genes associated with Kinase Inhibitor Kinome 439 Genes associated with Kinase Inhibitor Kinome_439, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB TAX013609 GO:0001091 molecular function RNA polymerase II basal transcription factor binding Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, any (more detail) 14 NA Homo sapiens

GOA MEX000331 Genes associated with Approved Drug trazodone Genes associated with Approved Drug trazodone, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002204 Genes associated with Kinase Inhibitor curcumin Genes associated with Kinase Inhibitor curcumin, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX013471 Genes associated with Computational Drug Signature Lithocholate Genes associated with Computational Drug Signature Lithocholate, curated by the Drug Signature Datab (more detail) 14 25990557 Homo sapiens

DSigDB TAX013883 GO:0001846 molecular function opsonin binding Interacting selectively and non-covalently with an opsonin, such as a complement component or antibo (more detail) 14 NA Homo sapiens

GOA MOX018040 Genes associated with Computational Drug Signature VANADIUM Genes associated with Computational Drug Signature VANADIUM, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB MOX017774 Genes associated with Computational Drug Signature Sufentanil citrate Genes associated with Computational Drug Signature Sufentanil citrate, curated by the Drug Signature (more detail) 14 25990557 Homo sapiens

DSigDB PEX001097 Ank: Ankyrin repeat Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectr (more detail) 14 NA Homo sapiens

Pfam WAG000409 eukaryotic protein translation The scanning translation initiation model suggests that 40S ribosomal subunit preloaded with factors (more detail) 14 NA Homo sapiens

BioCarta WAG001077 Apoptotic cleavage of cellular proteins (more detail) 14 NA Homo sapiens

Reactome MEX002622 Genes associated with Perturbagen Signature apomorphine Genes associated with Perturbagen Signature apomorphine, curated by the Drug Signature Database (DSi (more detail) 14 25990557 Homo sapiens

DSigDB MOX003416 Genes associated with Computational Drug Signature Tesaglitazar Genes associated with Computational Drug Signature Tesaglitazar, curated by the Drug Signature Datab (more detail) 14 25990557 Homo sapiens

DSigDB MOX001245 Genes associated with Computational Drug Signature SODIUM CHROMATE Genes associated with Computational Drug Signature SODIUM CHROMATE, curated by the Drug Signature Da (more detail) 14 25990557 Homo sapiens

DSigDB MOX004677 Genes associated with Computational Drug Signature spermine Genes associated with Computational Drug Signature spermine, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB MOX003955 Genes associated with Computational Drug Signature diazoxide Genes associated with Computational Drug Signature diazoxide, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB MOX010752 Genes associated with Computational Drug Signature CHEMBL460515 Genes associated with Computational Drug Signature CHEMBL460515, curated by the Drug Signature Datab (more detail) 14 25990557 Homo sapiens

DSigDB FEX002264 Lymphoma Hummel06 24genes 5.3.2 Probesets showing a lower average expression level in mBL (more detail) 14 16760442 Homo sapiens

GeneSigDB FEX001254 Leukemia Li02 16genes Table 3. Partially Up-Regulated Genes in Patients with CML (more detail) 14 12041670 Homo sapiens

GeneSigDB MEX002824 Genes associated with Perturbagen Signature celecoxib Genes associated with Perturbagen Signature celecoxib, curated by the Drug Signature Database (DSigD (more detail) 14 25990557 Homo sapiens

DSigDB MOX003817 Genes associated with Computational Drug Signature cephalothin Genes associated with Computational Drug Signature cephalothin, curated by the Drug Signature Databa (more detail) 14 25990557 Homo sapiens

DSigDB TAX016952 GO:0007512 biological process adult heart development The process whose specific outcome is the progression of the adult heart over time, from its formati (more detail) 14 NA Homo sapiens

GOA TAX018107 GO:0010766 biological process negative regulation of sodium ion transport Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na (more detail) 14 NA Homo sapiens

GOA MOX016407 Genes associated with Computational Drug Signature Bromocresol green Genes associated with Computational Drug Signature Bromocresol green, curated by the Drug Signature (more detail) 14 25990557 Homo sapiens

DSigDB TAX027982 GO:0060546 biological process negative regulation of necroptotic process Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell d (more detail) 12 NA Homo sapiens

GOA IEI008425 Protein protein interactors of human gene MYDGF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYDGF (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX022032 GO:0033197 biological process response to vitamin E Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 12 NA Homo sapiens

GOA IEI003447 Protein protein interactors of human gene DEDD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DEDD2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX025271 GO:0045779 biological process negative regulation of bone resorption Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption. (more detail) 12 NA Homo sapiens

GOA IEI008943 Protein protein interactors of human gene NOP14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOP14 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI002952 Protein protein interactors of human gene CR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CR2 (SwissProt ID=P2 (more detail) 12 17535438 Homo sapiens

I2D IEI004492 Protein protein interactors of human gene FAM193B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM193B (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI005636 Protein protein interactors of human gene GZMM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GZMM (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI000378 Protein protein interactors of human gene AGTR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AGTR2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI005977 Protein protein interactors of human gene HOXB6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXB6 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI012647 Protein protein interactors of human gene SMTN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMTN (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI006266 Protein protein interactors of human gene IGSF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGSF1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI013536 Protein protein interactors of human gene TEAD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TEAD2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI000412 Protein protein interactors of human gene AK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AK1 (SwissProt ID=P0 (more detail) 12 17535438 Homo sapiens

I2D IEI000529 Protein protein interactors of human gene AMER1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AMER1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI014398 Protein protein interactors of human gene TSSK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TSSK2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX021488 GO:0032372 biological process negative regulation of sterol transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement (more detail) 12 NA Homo sapiens

GOA TAX022860 GO:0035404 biological process histone serine phosphorylation The modification of histones by addition of a phosphate group to a serine residue. (more detail) 12 NA Homo sapiens

GOA TAX022816 GO:0035325 molecular function Toll like receptor binding Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor (more detail) 12 NA Homo sapiens

GOA TAX024474 GO:0043616 biological process keratinocyte proliferation The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population (more detail) 12 NA Homo sapiens

GOA TAX026651 GO:0050872 biological process white fat cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a white adipoc (more detail) 12 NA Homo sapiens

GOA TAX020570 GO:0030575 biological process nuclear body organization A process that is carried out at the cellular level which results in the assembly, arrangement of co (more detail) 12 NA Homo sapiens

GOA IEI008891 Protein protein interactors of human gene NMD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NMD3 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI015417 Protein protein interactors of human gene ZNF205 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF205 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI001242 Protein protein interactors of human gene BAZ2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BAZ2B (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX021335 GO:0032096 biological process negative regulation of response to food Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food s (more detail) 12 NA Homo sapiens

GOA IEI003593 Protein protein interactors of human gene DLGAP5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLGAP5 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI010459 Protein protein interactors of human gene PRG2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRG2 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI005164 Protein protein interactors of human gene GFPT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GFPT2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI005395 Protein protein interactors of human gene GPC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GPC1 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI006937 Protein protein interactors of human gene KLHL35 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHL35 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI014194 Protein protein interactors of human gene TRAT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRAT1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI008128 Protein protein interactors of human gene MPHOSPH10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MPHOSPH10 (SwissProt (more detail) 12 17535438 Homo sapiens

I2D IEI003719 Protein protein interactors of human gene DOCK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DOCK4 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI004061 Protein protein interactors of human gene EIF4EBP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF4EBP3 (SwissProt (more detail) 12 17535438 Homo sapiens

I2D IEI005875 Protein protein interactors of human gene HLA DQA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HLA-DQA1 (SwissProt (more detail) 12 17535438 Homo sapiens

I2D IEI000209 Protein protein interactors of human gene ADA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADA (SwissProt ID=P0 (more detail) 12 17535438 Homo sapiens

I2D TAX021338 GO:0032099 biological process negative regulation of appetite Any process that reduces appetite. (more detail) 12 NA Homo sapiens

GOA TAX021232 GO:0031932 cellular component TORC2 complex A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive (more detail) 12 NA Homo sapiens

GOA TAX017338 GO:0008540 cellular component proteasome regulatory particle, base subcomplex The subcomplex of the proteasome regulatory particle that directly associates with the proteasome co (more detail) 12 NA Homo sapiens

GOA TAX026019 GO:0048012 biological process hepatocyte growth factor receptor signaling pathway The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor (more detail) 12 NA Homo sapiens

GOA TAX032470 GO:1902306 biological process negative regulation of sodium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembran (more detail) 12 NA Homo sapiens

GOA TAX028082 GO:0060707 biological process trophoblast giant cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a trophoblast (more detail) 12 NA Homo sapiens

GOA IEI009194 Protein protein interactors of human gene NVL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NVL (SwissProt ID=O1 (more detail) 12 17535438 Homo sapiens

I2D IEI009952 Protein protein interactors of human gene PIP4K2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIP4K2B (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI010437 Protein protein interactors of human gene PRDM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRDM2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI004643 Protein protein interactors of human gene FBXO30 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO30 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI006323 Protein protein interactors of human gene IL1RL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL1RL1 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI001620 Protein protein interactors of human gene C4BPA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C4BPA (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI012861 Protein protein interactors of human gene SPECC1L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPECC1L (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI000234 Protein protein interactors of human gene ADAMTS4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADAMTS4 (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI007030 Protein protein interactors of human gene KRT35 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KRT35 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI007404 Protein protein interactors of human gene LRP5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRP5 (SwissProt ID=O (more detail) 12 17535438 Homo sapiens

I2D TAX021491 GO:0032375 biological process negative regulation of cholesterol transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement (more detail) 12 NA Homo sapiens

GOA MOX002018 Genes associated with Computational Drug Signature 1,1 Bis(4 hydroxyphenyl) 2 phenylbut 1 ene Genes associated with Computational Drug Signature 1,1-Bis(4-hydroxyphenyl)-2-phenylbut-1-ene, curat (more detail) 12 25990557 Homo sapiens

DSigDB MEX001806 Genes associated with Kinase Inhibitor Vandetanib Genes associated with Kinase Inhibitor Vandetanib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MOX001153 Genes associated with Computational Drug Signature 64551 89 9 Genes associated with Computational Drug Signature 64551-89-9, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB MOX005134 Genes associated with Computational Drug Signature PERINDOPRIL Genes associated with Computational Drug Signature PERINDOPRIL, curated by the Drug Signature Databa (more detail) 12 25990557 Homo sapiens

DSigDB TAX013805 GO:0001741 cellular component XY body A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has beco (more detail) 12 NA Homo sapiens

GOA MEX002834 Genes associated with Perturbagen Signature chlorcyclizine Genes associated with Perturbagen Signature chlorcyclizine, curated by the Drug Signature Database ( (more detail) 12 25990557 Homo sapiens

DSigDB MOX002319 Genes associated with Computational Drug Signature mycophenolate mofetil Genes associated with Computational Drug Signature mycophenolate mofetil, curated by the Drug Signat (more detail) 12 25990557 Homo sapiens

DSigDB TAX015639 GO:0005165 molecular function neurotrophin receptor binding Interacting selectively and non-covalently with a neurotrophin receptor. (more detail) 12 NA Homo sapiens

GOA MOX018043 Genes associated with Computational Drug Signature Vatalanib succinate Genes associated with Computational Drug Signature Vatalanib succinate, curated by the Drug Signatur (more detail) 12 25990557 Homo sapiens

DSigDB MOX016571 Genes associated with Computational Drug Signature triazolam Genes associated with Computational Drug Signature triazolam, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB MOX015623 Genes associated with Computational Drug Signature Trifluridine Genes associated with Computational Drug Signature Trifluridine, curated by the Drug Signature Datab (more detail) 12 25990557 Homo sapiens

DSigDB WAG000450 S1P1 pathway (more detail) 12 NA Homo sapiens

NCI-Nature Curated WAG001032 rb tumor suppressor/checkpoint signaling in response to dna damage Cell cycle checkpoint controls at the G1 to S transition and the G2 to M transition prevent the cell (more detail) 12 NA Homo sapiens

BioCarta FEX001781 Lung Ye01 14genes Table 5. Biosynthesis and metabolism genes (more detail) 12 11678601 Homo sapiens

GeneSigDB FEX002748 Skin VanGele04 12genes Table 3a List of MCC and SCLC classifier genes (MCC specific genes) (more detail) 12 14755241 Homo sapiens

GeneSigDB MAX000646 The lung adenocarcinoma TSP (tumor sequencing project) genes with significantly higher frequencies of nonsense, splice site, and frame shift mutations. Determining the genetic basis of cancer requires comprehensive analyses of large collections of hist (more detail) 12 NA Homo sapiens

MSigDB WIG000203 Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. na (more detail) 12 NA Homo sapiens

MSigDB MEX003404 Genes associated with Perturbagen Signature ipratropium bromide Genes associated with Perturbagen Signature ipratropium bromide, curated by the Drug Signature Datab (more detail) 12 25990557 Homo sapiens

DSigDB MEX001644 Genes associated with Kinase Inhibitor 172889 27 9 Genes associated with Kinase Inhibitor 172889-27-9, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001510 Genes associated with Kinase Inhibitor go 6983 Genes associated with Kinase Inhibitor go 6983, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB FEX002177 Lymphoma Zhu02 12genes Table IV. Genes found to be differentially deregulated in common and blastoid variant MCL. (more detail) 12 12472567 Homo sapiens

GeneSigDB MEX002692 Genes associated with Perturbagen Signature bepridil Genes associated with Perturbagen Signature bepridil, curated by the Drug Signature Database (DSigDB (more detail) 12 25990557 Homo sapiens

DSigDB MOX003585 Genes associated with Computational Drug Signature Trametinib Genes associated with Computational Drug Signature Trametinib, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB TAX017221 GO:0008356 biological process asymmetric cell division The asymmetric division of cells to produce two daughter cells with different developmental potentia (more detail) 12 NA Homo sapiens

GOA MOX000257 Genes associated with Computational Drug Signature Propyl 4 hydroxybenzoate Genes associated with Computational Drug Signature Propyl 4-hydroxybenzoate, curated by the Drug Sig (more detail) 12 25990557 Homo sapiens

DSigDB MOX000332 Genes associated with Computational Drug Signature Triphenyltin hydroxide Genes associated with Computational Drug Signature Triphenyltin hydroxide, curated by the Drug Signa (more detail) 12 25990557 Homo sapiens

DSigDB MOX004952 Genes associated with Computational Drug Signature 38966 21 1 Genes associated with Computational Drug Signature 38966-21-1, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB MOX002058 Genes associated with Computational Drug Signature Triflumizole Genes associated with Computational Drug Signature Triflumizole, curated by the Drug Signature Datab (more detail) 12 25990557 Homo sapiens

DSigDB MOX012285 Genes associated with Computational Drug Signature dienestrol Genes associated with Computational Drug Signature dienestrol, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB MOX012907 Genes associated with Computational Drug Signature Go 6976 Genes associated with Computational Drug Signature Go 6976, curated by the Drug Signature Database ( (more detail) 12 25990557 Homo sapiens

DSigDB TAX014484 GO:0002864 biological process regulation of acute inflammatory response to antigenic stimulus Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an an (more detail) 12 NA Homo sapiens

GOA TAX014510 GO:0002903 biological process negative regulation of B cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic proc (more detail) 12 NA Homo sapiens

GOA MOX016452 Genes associated with Computational Drug Signature CEPHARANTHINE Genes associated with Computational Drug Signature CEPHARANTHINE, curated by the Drug Signature Data (more detail) 12 25990557 Homo sapiens

DSigDB PEX001246 UCH: Ubiquitin carboxyl terminal hydrolase (more detail) 12 NA Homo sapiens

Pfam WIG000454 Trka Receptor Signaling Pathway Nerve growth factor (NGF) is a neurotrophic factor that stimulates neuronal survival and growth thro (more detail) 12 NA Homo sapiens

MSigDB WIG000251 Rho Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation The A-kinase anchor protein 13 (AKAP13, also known as AKAP-LBC) is one of a group of structurally di (more detail) 12 NA Homo sapiens

MSigDB MOX001101 Genes associated with Computational Drug Signature 4 Methylhistamine Genes associated with Computational Drug Signature 4-Methylhistamine, curated by the Drug Signature (more detail) 12 25990557 Homo sapiens

DSigDB MEX003990 Genes associated with Perturbagen Signature promazine Genes associated with Perturbagen Signature promazine, curated by the Drug Signature Database (DSigD (more detail) 12 25990557 Homo sapiens

DSigDB TAX000172 Genes annotated by the GO term GO:0030330. A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. (more detail) 12 NA Homo sapiens

MSigDB TAX000515 Genes annotated by the GO term GO:0050714. Any process that activates or increases the frequency, rate or extent of the regulated release of a protein from a cell or group of cells. (more detail) 12 NA Homo sapiens

MSigDB MOX003109 Genes associated with Computational Drug Signature 1 BROMOPROPANE Genes associated with Computational Drug Signature 1-BROMOPROPANE, curated by the Drug Signature Dat (more detail) 12 25990557 Homo sapiens

DSigDB WIG000406 Phospholipase C epsilon pathway Proposed model for b2-AR- and prostanoid-receptor-mediated PLC and calcium signalling. Receptors cou (more detail) 12 NA Homo sapiens

MSigDB WIG000260 Antigen Dependent B Cell Activation A key part of the immune system is the production of immunoglobulins (antibodies) by B cells to bind (more detail) 12 NA Homo sapiens

MSigDB WIG000288 Cystic Fibrosis Transmembrane Conductance Regulator And Beta 2 Adrenergic Receptor Pathway The defects in cAMP-regulated chloride channel CTFR are believed to be the major cause for cystic fi (more detail) 12 NA Homo sapiens

MSigDB TAX001299 Genes annotated by the GO term GO:0019902. Interacting selectively with any phosphatase. (more detail) 12 NA Homo sapiens

MSigDB WIG000840 Genes involved in FGFR4 ligand binding and activation (more detail) 12 NA Homo sapiens

MSigDB MEX002294 Genes associated with Kinase Inhibitor PYRAZOLOPYRIDAZINE 1 Genes associated with Kinase Inhibitor PYRAZOLOPYRIDAZINE 1, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB MEX002002 Genes associated with Kinase Inhibitor Aurora Kinase/Cdk Inhibitor Genes associated with Kinase Inhibitor Aurora Kinase/Cdk Inhibitor, curated by the Drug Signature Da (more detail) 12 25990557 Homo sapiens

DSigDB MOX003802 Genes associated with Computational Drug Signature cccp Genes associated with Computational Drug Signature cccp, curated by the Drug Signature Database (DSi (more detail) 12 25990557 Homo sapiens

DSigDB MOX012000 Genes associated with Computational Drug Signature Cladribine Genes associated with Computational Drug Signature Cladribine, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB TAX016866 GO:0007252 biological process I kappaB phosphorylation The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosph (more detail) 12 NA Homo sapiens

GOA MOX016995 Genes associated with Computational Drug Signature Genipin Genes associated with Computational Drug Signature Genipin, curated by the Drug Signature Database ( (more detail) 12 25990557 Homo sapiens

DSigDB MOX017088 Genes associated with Computational Drug Signature Paricalcitol Genes associated with Computational Drug Signature Paricalcitol, curated by the Drug Signature Datab (more detail) 12 25990557 Homo sapiens

DSigDB MEX001931 Genes associated with Kinase Inhibitor GW305178X Genes associated with Kinase Inhibitor GW305178X, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MOX000823 Genes associated with Computational Drug Signature Enilconazole Genes associated with Computational Drug Signature Enilconazole, curated by the Drug Signature Datab (more detail) 12 25990557 Homo sapiens

DSigDB MOX004543 Genes associated with Computational Drug Signature PIPERONYL BUTOXIDE Genes associated with Computational Drug Signature PIPERONYL BUTOXIDE, curated by the Drug Signature (more detail) 12 25990557 Homo sapiens

DSigDB FEX001052 Glioblastoma Morandi08 22genes Table 1. List of Genes up-regulated following CPT treatment in both U87-MG and DBTRG-05 cells; first (more detail) 12 18694480 Homo sapiens

GeneSigDB FEX001636 Leukemia Stumpel09 20genes 2C Table S2. The top 20 of genes most significantly hypermethylated in each genetic subtype of infant A (more detail) 12 19855078 Homo sapiens

GeneSigDB TAX022682 GO:0034983 biological process peptidyl lysine deacetylation The removal of an acetyl group from an acetylated lysine residue in a peptide or protein. (more detail) 7 NA Homo sapiens

GOA TAX023326 GO:0036302 biological process atrioventricular canal development The progression of the atrioventricular canal over time, from its formation to the mature structure. (more detail) 7 NA Homo sapiens

GOA TAX016824 GO:0007183 biological process SMAD protein complex assembly The aggregation, arrangement and bonding together of a set of components to form a protein complex t (more detail) 7 NA Homo sapiens

GOA TAX030298 GO:0090045 biological process positive regulation of deacetylase activity Any process that activates or increases the frequency, rate or extent of deacetylase activity, the c (more detail) 7 NA Homo sapiens

GOA TAX029896 GO:0072203 biological process cell proliferation involved in metanephros development The multiplication or reproduction of cells, resulting in the expansion of the population in the met (more detail) 7 NA Homo sapiens

GOA TAX025072 GO:0045343 biological process regulation of MHC class I biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 7 NA Homo sapiens

GOA TAX021322 GO:0032075 biological process positive regulation of nuclease activity Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydr (more detail) 7 NA Homo sapiens

GOA TAX023051 GO:0035726 biological process common myeloid progenitor cell proliferation The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of (more detail) 7 NA Homo sapiens

GOA TAX030429 GO:0090240 biological process positive regulation of histone H4 acetylation Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modificatio (more detail) 7 NA Homo sapiens

GOA TAX030494 GO:0090324 biological process negative regulation of oxidative phosphorylation Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 7 NA Homo sapiens

GOA TAX017960 GO:0010533 biological process regulation of activation of Janus kinase activity Any process that modulates the frequency or rate of activation of JAK (Janus Activated Kinase) prote (more detail) 7 NA Homo sapiens

GOA TAX024930 GO:0045075 biological process regulation of interleukin 12 biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 7 NA Homo sapiens

GOA TAX024130 GO:0043045 biological process DNA methylation involved in embryo development The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regula (more detail) 7 NA Homo sapiens

GOA TAX019429 GO:0017182 biological process peptidyl diphthamide metabolic process The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue. (more detail) 7 NA Homo sapiens

GOA TAX025340 GO:0045916 biological process negative regulation of complement activation Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation. (more detail) 7 NA Homo sapiens

GOA TAX027526 GO:0055009 biological process atrial cardiac muscle tissue morphogenesis The process in which the anatomical structure of cardiac atrium muscle is generated and organized. (more detail) 7 NA Homo sapiens

GOA TAX033240 GO:1903980 biological process positive regulation of microglial cell activation Any process that activates or increases the frequency, rate or extent of microglial cell activation. (more detail) 7 NA Homo sapiens

GOA TAX019931 GO:0021520 biological process spinal cord motor neuron cell fate specification The process in which a cell becomes capable of differentiating autonomously into a motor neuron in a (more detail) 7 NA Homo sapiens

GOA TAX032151 GO:1901535 biological process regulation of DNA demethylation Any process that modulates the frequency, rate or extent of DNA demethylation. (more detail) 7 NA Homo sapiens

GOA TAX031828 GO:1900125 biological process regulation of hyaluronan biosynthetic process Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process. (more detail) 7 NA Homo sapiens

GOA TAX034530 GO:2000197 biological process regulation of ribonucleoprotein complex localization Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization. (more detail) 7 NA Homo sapiens

GOA IEI015314 Protein protein interactors of human gene ZFP42 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZFP42 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI002258 Protein protein interactors of human gene CDK5RAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK5RAP1 (SwissProt (more detail) 7 17535438 Homo sapiens

I2D IEI002427 Protein protein interactors of human gene CFDP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CFDP1 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI011337 Protein protein interactors of human gene RIPPLY1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RIPPLY1 (SwissProt I (more detail) 7 17535438 Homo sapiens

I2D TAX017362 GO:0008595 biological process anterior/posterior axis specification, embryo The specification of the anterior/posterior axis of the embryo by the products of genes expressed ma (more detail) 7 NA Homo sapiens

GOA TAX022904 GO:0035507 biological process regulation of myosin light chain phosphatase activity Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity. (more detail) 7 NA Homo sapiens

GOA TAX022248 GO:0033864 biological process positive regulation of NAD(P)H oxidase activity Any process that activates or increases the activity of the enzyme NAD(P)H oxidase. (more detail) 7 NA Homo sapiens

GOA TAX021593 GO:0032489 biological process regulation of Cdc42 protein signal transduction Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction. (more detail) 7 NA Homo sapiens

GOA TAX023954 GO:0042661 biological process regulation of mesodermal cell fate specification Any process that modulates the frequency, rate or extent of mesoderm cell fate specification. (more detail) 7 NA Homo sapiens

GOA TAX026179 GO:0048478 biological process replication fork protection Any process that prevents the collapse of stalled replication forks. (more detail) 7 NA Homo sapiens

GOA TAX026264 GO:0048644 biological process muscle organ morphogenesis The process in which the anatomical structures of muscle are generated and organized. (more detail) 7 NA Homo sapiens

GOA TAX025261 GO:0045762 biological process positive regulation of adenylate cyclase activity Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity. (more detail) 7 NA Homo sapiens

GOA TAX032507 GO:1902416 biological process positive regulation of mRNA binding Any process that activates or increases the frequency, rate or extent of mRNA binding. (more detail) 7 NA Homo sapiens

GOA TAX032697 GO:1902915 biological process negative regulation of protein polyubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitinat (more detail) 7 NA Homo sapiens

GOA IEI015050 Protein protein interactors of human gene WFIKKN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WFIKKN2 (SwissProt I (more detail) 7 17535438 Homo sapiens

I2D IEI002576 Protein protein interactors of human gene CKAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CKAP2 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI003323 Protein protein interactors of human gene DBR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DBR1 (SwissProt ID=Q (more detail) 7 17535438 Homo sapiens

I2D TAX019430 GO:0017183 biological process peptidyl diphthamide biosynthetic process from peptidyl histidine The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, (more detail) 7 NA Homo sapiens

GOA TAX022286 GO:0034046 molecular function poly(G) binding Interacting selectively and non-covalently with a sequence of guanine residues in an RNA molecule. (more detail) 7 NA Homo sapiens

GOA TAX026028 GO:0048021 biological process regulation of melanin biosynthetic process Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulti (more detail) 7 NA Homo sapiens

GOA TAX020440 GO:0030297 molecular function transmembrane receptor protein tyrosine kinase activator activity Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase. (more detail) 7 NA Homo sapiens

GOA TAX034047 GO:1905770 biological process regulation of mesodermal cell differentiation Any process that modulates the frequency, rate or extent of mesodermal cell differentiation. (more detail) 7 NA Homo sapiens

GOA TAX031754 GO:0150078 biological process positive regulation of neuroinflammatory response Any process that activates or increases the frequency, rate or extent of neuroinflammatory response. (more detail) 7 NA Homo sapiens

GOA TAX031887 GO:1900226 biological process negative regulation of NLRP3 inflammasome complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome comp (more detail) 7 NA Homo sapiens

GOA TAX034815 GO:2000617 biological process positive regulation of histone H3 K9 acetylation Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation. (more detail) 7 NA Homo sapiens

GOA TAX028066 GO:0060687 biological process regulation of branching involved in prostate gland morphogenesis Any process that modulates the rate, frequency, or extent of prostate gland branching, the process i (more detail) 7 NA Homo sapiens

GOA TAX032343 GO:1902031 biological process regulation of NADP metabolic process Any process that modulates the frequency, rate or extent of NADP metabolic process. (more detail) 7 NA Homo sapiens

GOA TAX032786 GO:1903071 biological process positive regulation of ER associated ubiquitin dependent protein catabolic process Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dep (more detail) 7 NA Homo sapiens

GOA TAX034510 GO:2000169 biological process regulation of peptidyl cysteine S nitrosylation Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. (more detail) 7 NA Homo sapiens

GOA IEI001756 Protein protein interactors of human gene CAMKV from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAMKV (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI015726 Protein protein interactors of human gene ZNF711 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF711 (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI003622 Protein protein interactors of human gene DMTF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DMTF1 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI005792 Protein protein interactors of human gene HELZ2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HELZ2 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI005994 Protein protein interactors of human gene HOXD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXD3 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI006340 Protein protein interactors of human gene IL27 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL27 (SwissProt ID=Q (more detail) 7 17535438 Homo sapiens

I2D IEI013126 Protein protein interactors of human gene STK35 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STK35 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI007341 Protein protein interactors of human gene LMX1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LMX1A (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D TAX030128 GO:0072711 biological process cellular response to hydroxyurea Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 7 NA Homo sapiens

GOA IEI011650 Protein protein interactors of human gene RSBN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RSBN1 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI011669 Protein protein interactors of human gene RSRP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RSRP1 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI011773 Protein protein interactors of human gene SALL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SALL4 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI011960 Protein protein interactors of human gene SELENON from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SELENON (SwissProt I (more detail) 7 17535438 Homo sapiens

I2D IEI012197 Protein protein interactors of human gene SHROOM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SHROOM2 (SwissProt I (more detail) 7 17535438 Homo sapiens

I2D IEI014898 Protein protein interactors of human gene VPS13A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VPS13A (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI002830 Protein protein interactors of human gene COMMD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD2 (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI004445 Protein protein interactors of human gene FAM120C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM120C (SwissProt I (more detail) 7 17535438 Homo sapiens

I2D IEI011121 Protein protein interactors of human gene RC3H1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RC3H1 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI012642 Protein protein interactors of human gene SMPD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMPD4 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI012903 Protein protein interactors of human gene SPOUT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPOUT1 (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI000754 Protein protein interactors of human gene APOL5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APOL5 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI007570 Protein protein interactors of human gene MAFA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAFA (SwissProt ID=Q (more detail) 7 17535438 Homo sapiens

I2D IEI001447 Protein protein interactors of human gene BRPF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRPF3 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D TAX021104 GO:0031658 biological process negative regulation of cyclin dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent prote (more detail) 7 NA Homo sapiens

GOA IEI015074 Protein protein interactors of human gene WNT5A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WNT5A (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI015217 Protein protein interactors of human gene ZBTB4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB4 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI015525 Protein protein interactors of human gene ZNF397 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF397 (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI009782 Protein protein interactors of human gene PFKFB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PFKFB1 (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI015846 Protein protein interactors of human gene ZSCAN22 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZSCAN22 (SwissProt I (more detail) 7 17535438 Homo sapiens

I2D IEI003200 Protein protein interactors of human gene CXXC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CXXC5 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI005891 Protein protein interactors of human gene HLX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HLX (SwissProt ID=Q1 (more detail) 7 17535438 Homo sapiens

I2D IEI012686 Protein protein interactors of human gene SNRNP35 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRNP35 (SwissProt I (more detail) 7 17535438 Homo sapiens

I2D IEI006855 Protein protein interactors of human gene KIFC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIFC1 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI014139 Protein protein interactors of human gene TPPP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TPPP (SwissProt ID=O (more detail) 7 17535438 Homo sapiens

I2D IEI001293 Protein protein interactors of human gene BCL9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCL9 (SwissProt ID=O (more detail) 7 17535438 Homo sapiens

I2D IEI010588 Protein protein interactors of human gene PRSS50 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRSS50 (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI007339 Protein protein interactors of human gene LMTK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LMTK2 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI001660 Protein protein interactors of human gene C9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C9 (SwissProt ID=P02 (more detail) 7 17535438 Homo sapiens

I2D TAX028002 GO:0060575 biological process intestinal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cub (more detail) 7 NA Homo sapiens

GOA TAX030587 GO:0090647 biological process modulation of age related behavioral decline Any process that modulates the processes that arise as an organism progresses toward the end of its (more detail) 7 NA Homo sapiens

GOA TAX028980 GO:0070531 cellular component BRCA1 A complex A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, (more detail) 7 NA Homo sapiens

GOA TAX024860 GO:0044806 biological process G quadruplex DNA unwinding The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure hel (more detail) 7 NA Homo sapiens

GOA TAX026726 GO:0051001 biological process negative regulation of nitric oxide synthase activity Any process that stops or reduces the activity of the enzyme nitric-oxide synthase. (more detail) 7 NA Homo sapiens

GOA TAX025183 GO:0045630 biological process positive regulation of T helper 2 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentia (more detail) 7 NA Homo sapiens

GOA TAX020045 GO:0021781 biological process glial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop i (more detail) 7 NA Homo sapiens

GOA TAX020087 GO:0021861 biological process forebrain radial glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, speci (more detail) 7 NA Homo sapiens

GOA TAX033706 GO:1904948 biological process midbrain dopaminergic neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a midbrain (more detail) 7 NA Homo sapiens

GOA TAX032515 GO:1902455 biological process negative regulation of stem cell population maintenance Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population ma (more detail) 7 NA Homo sapiens

GOA TAX032016 GO:1901098 biological process positive regulation of autophagosome maturation Any process that activates or increases the frequency, rate or extent of autophagosome maturation. (more detail) 7 NA Homo sapiens

GOA TAX034562 GO:2000258 biological process negative regulation of protein activation cascade Any process that stops, prevents or reduces the frequency, rate or extent of protein activation casc (more detail) 7 NA Homo sapiens

GOA TAX028307 GO:0061101 biological process neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or function (more detail) 7 NA Homo sapiens

GOA TAX028319 GO:0061133 molecular function endopeptidase activator activity Increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in (more detail) 7 NA Homo sapiens

GOA TAX017384 GO:0008635 biological process activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the co (more detail) 7 NA Homo sapiens

GOA TAX029473 GO:0071455 biological process cellular response to hyperoxia Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 7 NA Homo sapiens

GOA TAX029507 GO:0071499 biological process cellular response to laminar fluid shear stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 7 NA Homo sapiens

GOA TAX022773 GO:0035242 molecular function protein arginine omega N asymmetric methyltransferase activity Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is o (more detail) 7 NA Homo sapiens

GOA TAX023481 GO:0038066 biological process p38MAPK cascade An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cas (more detail) 7 NA Homo sapiens

GOA TAX031094 GO:0098722 biological process asymmetric stem cell division Division of a stem cell during which it retains its identity and buds off a daughter cell with a new (more detail) 7 NA Homo sapiens

GOA TAX024061 GO:0042921 biological process glucocorticoid receptor signaling pathway Any series of molecular signals generated as a consequence of a glucocorticoid binding to its recept (more detail) 7 NA Homo sapiens

GOA TAX025100 GO:0045410 biological process positive regulation of interleukin 6 biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 7 NA Homo sapiens

GOA TAX021892 GO:0032960 biological process regulation of inositol trisphosphate biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 7 NA Homo sapiens

GOA TAX021105 GO:0031659 biological process positive regulation of cyclin dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein se (more detail) 7 NA Homo sapiens

GOA TAX021321 GO:0032074 biological process negative regulation of nuclease activity Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages wi (more detail) 7 NA Homo sapiens

GOA TAX021431 GO:0032278 biological process positive regulation of gonadotropin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a (more detail) 7 NA Homo sapiens

GOA TAX021809 GO:0032819 biological process positive regulation of natural killer cell proliferation Any process that activates or increases the frequency, rate or extent of natural killer cell prolife (more detail) 7 NA Homo sapiens

GOA TAX028930 GO:0070431 biological process nucleotide binding oligomerization domain containing 2 signaling pathway Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomer (more detail) 7 NA Homo sapiens

GOA TAX017364 GO:0008603 molecular function cAMP dependent protein kinase regulator activity Modulation of the activity of the enzyme cAMP-dependent protein kinase. (more detail) 7 NA Homo sapiens

GOA TAX029297 GO:0071141 cellular component SMAD protein complex A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric (more detail) 7 NA Homo sapiens

GOA TAX029872 GO:0072172 biological process mesonephric tubule formation The developmental process pertaining to the initial formation of a mesonephric tubule from unspecifi (more detail) 7 NA Homo sapiens

GOA TAX030797 GO:0097322 molecular function 7SK snRNA binding Interacting selectively and non-covalently with a 7SK small nuclear RNA (7SK snRNA). (more detail) 7 NA Homo sapiens

GOA TAX020961 GO:0031392 biological process regulation of prostaglandin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 7 NA Homo sapiens

GOA TAX019884 GO:0019919 biological process peptidyl arginine methylation, to asymmetrical dimethyl arginine The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-argini (more detail) 7 NA Homo sapiens

GOA TAX031736 GO:0150011 biological process regulation of neuron projection arborization Any process that modulates the frequency, rate or extent of the process in which the anatomical stru (more detail) 7 NA Homo sapiens

GOA TAX033040 GO:1903608 biological process protein localization to cytoplasmic stress granule A process in which a protein is transported to, or maintained in, a location within a cytoplasmic st (more detail) 7 NA Homo sapiens

GOA IEI008730 Protein protein interactors of human gene NEIL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEIL2 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D TAX034627 GO:2000347 biological process positive regulation of hepatocyte proliferation Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation. (more detail) 7 NA Homo sapiens

GOA TAX027991 GO:0060558 biological process regulation of calcidiol 1 monooxygenase activity Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calc (more detail) 7 NA Homo sapiens

GOA TAX029804 GO:0072050 biological process S shaped body morphogenesis The process in which the S-shaped body is generated and organized. The S-shaped body is the successo (more detail) 7 NA Homo sapiens

GOA TAX029157 GO:0070874 biological process negative regulation of glycogen metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 7 NA Homo sapiens

GOA TAX028862 GO:0070314 biological process G1 to G0 transition A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a spec (more detail) 7 NA Homo sapiens

GOA TAX024489 GO:0043633 biological process polyadenylation dependent RNA catabolic process The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by init (more detail) 7 NA Homo sapiens

GOA TAX021877 GO:0032933 biological process SREBP signaling pathway A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequen (more detail) 7 NA Homo sapiens

GOA TAX021243 GO:0031946 biological process regulation of glucocorticoid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 7 NA Homo sapiens

GOA TAX018820 GO:0016015 molecular function morphogen activity Acts as a trigger for a pattern specification process when present at a specific concentration withi (more detail) 7 NA Homo sapiens

GOA TAX020054 GO:0021798 biological process forebrain dorsal/ventral pattern formation The formation of specific regional progenitor domains along the dorsal-ventral axis in the developin (more detail) 7 NA Homo sapiens

GOA TAX019878 GO:0019907 cellular component cyclin dependent protein kinase activating kinase holoenzyme complex A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases b (more detail) 7 NA Homo sapiens

GOA TAX033623 GO:1904796 biological process regulation of core promoter binding Any process that modulates the frequency, rate or extent of core promoter binding. (more detail) 7 NA Homo sapiens

GOA TAX034098 GO:1905902 biological process regulation of mesoderm formation Any process that modulates the frequency, rate or extent of mesoderm formation. (more detail) 7 NA Homo sapiens

GOA TAX033804 GO:1905165 biological process regulation of lysosomal protein catabolic process Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process. (more detail) 7 NA Homo sapiens

GOA TAX034216 GO:1990316 cellular component Atg1/ULK1 kinase complex A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along w (more detail) 7 NA Homo sapiens

GOA IEI013704 Protein protein interactors of human gene TIGAR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TIGAR (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D TAX022055 GO:0033256 cellular component I kappaB/NF kappaB complex A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of a (more detail) 7 NA Homo sapiens

GOA TAX022800 GO:0035280 biological process miRNA loading onto RISC involved in gene silencing by miRNA The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing (more detail) 7 NA Homo sapiens

GOA TAX019329 GO:0017002 molecular function activin activated receptor activity Combining with activin and transmitting the signal from one side of the membrane to the other to ini (more detail) 7 NA Homo sapiens

GOA TAX027240 GO:0051890 biological process regulation of cardioblast differentiation Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process (more detail) 7 NA Homo sapiens

GOA TAX025348 GO:0045924 biological process regulation of female receptivity Any process that modulates the frequency, rate or extent of the willingness or readiness of a female (more detail) 7 NA Homo sapiens

GOA TAX020682 GO:0030870 cellular component Mre11 complex Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DN (more detail) 7 NA Homo sapiens

GOA TAX020407 GO:0030249 molecular function guanylate cyclase regulator activity Modulates the activity of guanylate cyclase. (more detail) 7 NA Homo sapiens

GOA TAX033941 GO:1905461 biological process positive regulation of vascular associated smooth muscle cell apoptotic process Any process that activates or increases the frequency, rate or extent of vascular associated smooth (more detail) 7 NA Homo sapiens

GOA TAX035025 GO:2001040 biological process positive regulation of cellular response to drug Any process that activates or increases the frequency, rate or extent of cellular response to drug. (more detail) 7 NA Homo sapiens

GOA TAX033091 GO:1903715 biological process regulation of aerobic respiration Any process that modulates the frequency, rate or extent of aerobic respiration. (more detail) 7 NA Homo sapiens

GOA TAX028371 GO:0061298 biological process retina vasculature development in camera type eye The process whose specific outcome is the progression of the vasculature of the retina over time, fr (more detail) 7 NA Homo sapiens

GOA TAX032361 GO:1902075 biological process cellular response to salt Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 7 NA Homo sapiens

GOA IEI001986 Protein protein interactors of human gene CCDC9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCDC9 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI008770 Protein protein interactors of human gene NEUROG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEUROG1 (SwissProt I (more detail) 7 17535438 Homo sapiens

I2D IEI002294 Protein protein interactors of human gene CDX4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDX4 (SwissProt ID=O (more detail) 7 17535438 Homo sapiens

I2D IEI004149 Protein protein interactors of human gene EMX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EMX1 (SwissProt ID=Q (more detail) 7 17535438 Homo sapiens

I2D IEI005054 Protein protein interactors of human gene GAMT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GAMT (SwissProt ID=Q (more detail) 7 17535438 Homo sapiens

I2D IEI005811 Protein protein interactors of human gene HESX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HESX1 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI013464 Protein protein interactors of human gene TBX5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBX5 (SwissProt ID=Q (more detail) 7 17535438 Homo sapiens

I2D TAX027610 GO:0060017 biological process parathyroid gland development The process whose specific outcome is the progression of the parathyroid gland over time, from its f (more detail) 7 NA Homo sapiens

GOA TAX026131 GO:0048293 biological process regulation of isotype switching to IgE isotypes Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes. (more detail) 7 NA Homo sapiens

GOA TAX025198 GO:0045650 biological process negative regulation of macrophage differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentia (more detail) 7 NA Homo sapiens

GOA TAX020107 GO:0021902 biological process commitment of neuronal cell to specific neuron type in forebrain The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain. (more detail) 7 NA Homo sapiens

GOA TAX031724 GO:0140223 molecular function general transcription initiation factor activity An activity that contributes to transcription start site selection and transcription initiation. (more detail) 7 NA Homo sapiens

GOA TAX031737 GO:0150012 biological process positive regulation of neuron projection arborization Any process that activates or increases the frequency, rate or extent of the process in which the an (more detail) 7 NA Homo sapiens

GOA TAX032154 GO:1901538 biological process changes to DNA methylation involved in embryo development The addition or removal of methyl groups to DNA that contributes to the epigenetic regulation of emb (more detail) 7 NA Homo sapiens

GOA TAX034199 GO:1990253 biological process cellular response to leucine starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 7 NA Homo sapiens

GOA TAX032246 GO:1901725 biological process regulation of histone deacetylase activity Any process that modulates the frequency, rate or extent of histone deacetylase activity. (more detail) 7 NA Homo sapiens

GOA TAX032670 GO:1902866 biological process regulation of retina development in camera type eye Any process that modulates the frequency, rate or extent of retina development in camera-type eye. (more detail) 7 NA Homo sapiens

GOA IEI002465 Protein protein interactors of human gene CHD5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD5 (SwissProt ID=Q (more detail) 7 17535438 Homo sapiens

I2D IEI002662 Protein protein interactors of human gene CLN6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLN6 (SwissProt ID=Q (more detail) 7 17535438 Homo sapiens

I2D IEI003845 Protein protein interactors of human gene DUSP22 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP22 (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI010958 Protein protein interactors of human gene RAG2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAG2 (SwissProt ID=P (more detail) 7 17535438 Homo sapiens

I2D IEI011309 Protein protein interactors of human gene RILP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RILP (SwissProt ID=Q (more detail) 7 17535438 Homo sapiens

I2D IEI005509 Protein protein interactors of human gene GRIN3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRIN3A (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI000534 Protein protein interactors of human gene AMHR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AMHR2 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI008348 Protein protein interactors of human gene MTMR4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTMR4 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI009665 Protein protein interactors of human gene PDE4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDE4A (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI003001 Protein protein interactors of human gene CROCC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CROCC (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI003927 Protein protein interactors of human gene EDA2R from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EDA2R (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI004307 Protein protein interactors of human gene ESRRB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ESRRB (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D IEI004460 Protein protein interactors of human gene FAM13A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM13A (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI005764 Protein protein interactors of human gene HDGFL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDGFL3 (SwissProt ID (more detail) 7 17535438 Homo sapiens

I2D IEI000710 Protein protein interactors of human gene APBB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APBB2 (SwissProt ID= (more detail) 7 17535438 Homo sapiens

I2D MOX003485 Genes associated with Computational Drug Signature Monascin Genes associated with Computational Drug Signature Monascin, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MOX002175 Genes associated with Computational Drug Signature Isoxaben Genes associated with Computational Drug Signature Isoxaben, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MOX002184 Genes associated with Computational Drug Signature AC1O5QSE Genes associated with Computational Drug Signature AC1O5QSE, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MOX002497 Genes associated with Computational Drug Signature Bupirimate Genes associated with Computational Drug Signature Bupirimate, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens

DSigDB MOX001139 Genes associated with Computational Drug Signature 1143 70 0 Genes associated with Computational Drug Signature 1143-70-0, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MOX004533 Genes associated with Computational Drug Signature Phytic acid Genes associated with Computational Drug Signature Phytic acid, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens

DSigDB MOX002220 Genes associated with Computational Drug Signature N (2 Aminoethyl) 5 chloroisoquinoline 8 sulfonamide Genes associated with Computational Drug Signature N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonami (more detail) 7 25990557 Homo sapiens

DSigDB MOX011199 Genes associated with Computational Drug Signature CHEMBL538718 Genes associated with Computational Drug Signature CHEMBL538718, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens

DSigDB TAX016867 GO:0007253 biological process cytoplasmic sequestering of NF kappaB The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytop (more detail) 7 NA Homo sapiens

GOA TAX017916 GO:0010452 biological process histone H3 K36 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of (more detail) 7 NA Homo sapiens

GOA FEX001025 Endometrial Salvesen09 11genes PeakRegions Table S4a. List of peak regions of amplification deletion and non-overlapping LOH (more detail) 7 19261849 Homo sapiens

GeneSigDB FEX000210 Brain Katsel08 10genes Table 6. Expression analysis of the cell cycle genes in ACG. Tissue samples from the ACG of controls (more detail) 7 18322470 Homo sapiens

GeneSigDB WAG000725 TNF signaling (more detail) 7 NA Homo sapiens

Reactome MEX001614 Genes associated with Kinase Inhibitor Kinome 245 Genes associated with Kinase Inhibitor Kinome_245, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MEX001845 Genes associated with Kinase Inhibitor Lapatinib Genes associated with Kinase Inhibitor Lapatinib, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MEX003356 Genes associated with Perturbagen Signature hydrocortisone Genes associated with Perturbagen Signature hydrocortisone, curated by the Drug Signature Database ( (more detail) 7 25990557 Homo sapiens

DSigDB MOX006664 Genes associated with Computational Drug Signature AGN PC 001QK8 Genes associated with Computational Drug Signature AGN-PC-001QK8, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens

DSigDB MOX004458 Genes associated with Computational Drug Signature oxprenolol Genes associated with Computational Drug Signature oxprenolol, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens

DSigDB MOX004766 Genes associated with Computational Drug Signature timolol Genes associated with Computational Drug Signature timolol, curated by the Drug Signature Database ( (more detail) 7 25990557 Homo sapiens

DSigDB MOX005843 Genes associated with Computational Drug Signature 3 (4 Hydroxy phenyl) 2,3 diphenyl acrylonitrile Genes associated with Computational Drug Signature 3-(4-Hydroxy-phenyl)-2,3-diphenyl-acrylonitrile, (more detail) 7 25990557 Homo sapiens

DSigDB TAX016869 GO:0007256 biological process activation of JNKK activity The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are i (more detail) 7 NA Homo sapiens

GOA TAX014089 GO:0002151 molecular function G quadruplex RNA binding Interacting selectively and non-covalently with G-quadruplex RNA structures, in which groups of four (more detail) 7 NA Homo sapiens

GOA MOX009490 Genes associated with Computational Drug Signature CHEMBL294120 Genes associated with Computational Drug Signature CHEMBL294120, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens

DSigDB MOX013491 Genes associated with Computational Drug Signature lonidamine Genes associated with Computational Drug Signature lonidamine, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens

DSigDB TAX016267 GO:0006348 biological process chromatin silencing at telomere Repression of transcription of telomeric DNA by altering the structure of chromatin. (more detail) 7 NA Homo sapiens

GOA TAX013622 GO:0001135 molecular function RNA polymerase II transcription regulator recruiting activity The function of binding to an RNA polymerase II (RNAP II) transcription factor and recruiting it to (more detail) 7 NA Homo sapiens

GOA TAX014707 GO:0003339 biological process regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell (more detail) 7 NA Homo sapiens

GOA MOX011736 Genes associated with Computational Drug Signature CHEMBL73495 Genes associated with Computational Drug Signature CHEMBL73495, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens

DSigDB MOX001870 Genes associated with Computational Drug Signature Kahweol acetate Genes associated with Computational Drug Signature Kahweol acetate, curated by the Drug Signature Da (more detail) 7 25990557 Homo sapiens

DSigDB MOX000175 Genes associated with Computational Drug Signature 2 HYDROXYETHYL METHACRYLATE Genes associated with Computational Drug Signature 2-HYDROXYETHYL METHACRYLATE, curated by the Drug (more detail) 7 25990557 Homo sapiens

DSigDB MOX000495 Genes associated with Computational Drug Signature palytoxin Genes associated with Computational Drug Signature palytoxin, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MOX006666 Genes associated with Computational Drug Signature AGN PC 001QKE Genes associated with Computational Drug Signature AGN-PC-001QKE, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens

DSigDB MOX004559 Genes associated with Computational Drug Signature potassium iodide Genes associated with Computational Drug Signature potassium iodide, curated by the Drug Signature D (more detail) 7 25990557 Homo sapiens

DSigDB MOX003152 Genes associated with Computational Drug Signature Resiquimod Genes associated with Computational Drug Signature Resiquimod, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens

DSigDB TAX014622 GO:0003183 biological process mitral valve morphogenesis The process in which the structure of the mitral valve is generated and organized. (more detail) 7 NA Homo sapiens

GOA MOX011743 Genes associated with Computational Drug Signature CHEMBL74983 Genes associated with Computational Drug Signature CHEMBL74983, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens

DSigDB MOX014397 Genes associated with Computational Drug Signature PD173955 Genes associated with Computational Drug Signature PD173955, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB TAX014325 GO:0002606 biological process positive regulation of dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen pro (more detail) 7 NA Homo sapiens

GOA TAX015808 GO:0005579 cellular component membrane attack complex A protein complex produced by sequentially activated components of the complement cascade inserted i (more detail) 7 NA Homo sapiens

GOA MOX014577 Genes associated with Computational Drug Signature PONATINIB Genes associated with Computational Drug Signature PONATINIB, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MAX001885 Nuclear receptors whose expression correlated with that of aromatase (CYP19A1) [GeneID=1588] in a panel of breast cancer biopsies. Aromatase is a key enzyme in intratumoral estrogen production required for the production of estroge (more detail) 7 NA Homo sapiens

MSigDB MEX001660 Genes associated with Kinase Inhibitor GW827099X Genes associated with Kinase Inhibitor GW827099X, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MEX001916 Genes associated with Kinase Inhibitor (E) N Methyl 2 ((3 (2 (pyridin 2 yl)vinyl) 1H indazol 6 yl)thio)benzamide Genes associated with Kinase Inhibitor (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)th (more detail) 7 25990557 Homo sapiens

DSigDB MOX001932 Genes associated with Computational Drug Signature Crystal violet lactone Genes associated with Computational Drug Signature Crystal violet lactone, curated by the Drug Signa (more detail) 7 25990557 Homo sapiens

DSigDB MOX003296 Genes associated with Computational Drug Signature Bosutinib Genes associated with Computational Drug Signature Bosutinib, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MEX002258 Genes associated with Kinase Inhibitor GW795486X Genes associated with Kinase Inhibitor GW795486X, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MEX003295 Genes associated with Perturbagen Signature glycocholic acid Genes associated with Perturbagen Signature glycocholic acid, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB WAG001360 Toll Like Receptor 3 (TLR3) Cascade (more detail) 7 NA Homo sapiens

Reactome GEX000995 leukemia, myeloid, acute leukemia, myeloid, acute associated genes. PAGER constructed this gene set by grouping all genes whi (more detail) 7 NA Homo sapiens

GAD MAX000314 Genes down regulated in tumor adjacent liver tissue, which is asociated with intrahepatic metastasis of hepatocellular carcinoma Hepatocellular carcinoma (HCC) is an aggressive malignancy mainly due to metastases or postsurgical (more detail) 7 NA Homo sapiens

MSigDB FAX000029 Targets of MicroRNA ACGCACA,MIR 210 (more detail) 7 NA Homo sapiens

MSigDB MAX002825 Genes down regulated in hES cells (human embryonic stem cells) after treatment with the ALK [GeneID=238] inhibitor SB 431542 [PubChem=4521392]. The application of human embryonic stem (ES) cells in medicine and biology has an inherent reliance (more detail) 7 NA Homo sapiens

MSigDB GEX168118 Stransky et al., 2011 08 26, Science, The Mutational Landscape of Head and Neck Squamous Cell Carcinoma Head and neck squamous cell carcinoma (HNSCC) Mutation type(Somatic mutation) (more detail) 7 21798893 Homo sapiens

NGS Catalog MEX000954 Genes associated with Approved Drug etretinate Genes associated with Approved Drug etretinate, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MEX001877 Genes associated with Kinase Inhibitor CHEMBL508928 Genes associated with Kinase Inhibitor CHEMBL508928, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens

DSigDB MOX001923 Genes associated with Computational Drug Signature Mafosfamide Genes associated with Computational Drug Signature Mafosfamide, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens

DSigDB MOX003409 Genes associated with Computational Drug Signature gw8510 Genes associated with Computational Drug Signature gw8510, curated by the Drug Signature Database (D (more detail) 7 25990557 Homo sapiens

DSigDB MOX004045 Genes associated with Computational Drug Signature Ephedrine Genes associated with Computational Drug Signature Ephedrine, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MOX004594 Genes associated with Computational Drug Signature Prostacycline Genes associated with Computational Drug Signature Prostacycline, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens

DSigDB MOX013239 Genes associated with Computational Drug Signature JNJ 10198409 Genes associated with Computational Drug Signature JNJ-10198409, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens

DSigDB TAX014698 GO:0003330 biological process regulation of extracellular matrix constituent secretion Any process that modulates the rate, frequency, or extent of the controlled release of molecules tha (more detail) 7 NA Homo sapiens

GOA PEX000267 BIR: Inhibitor of Apoptosis domain BIR stands for Baculovirus Inhibitor of apoptosis protein Repeat. It is found repeated in inhibitor (more detail) 7 NA Homo sapiens

Pfam TAX017984 GO:0010587 biological process miRNA catabolic process The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single (more detail) 7 NA Homo sapiens

GOA TAX015598 GO:0005114 molecular function type II transforming growth factor beta receptor binding Interacting selectively and non-covalently with a type II transforming growth factor beta receptor. (more detail) 7 NA Homo sapiens

GOA PEX002507 RNase PH: 3' exoribonuclease family, domain 1 This family includes 3-5 exoribonucleases. Ribonuclease PH contains a single copy of this domain, a (more detail) 7 NA Homo sapiens

Pfam PEX001284 Hist deacetyl: Histone deacetylase domain Histones can be reversibly acetylated on several lysine residues. Regulation of transcription is cau (more detail) 7 NA Homo sapiens

Pfam PEX001438 14 3 3: 14 3 3 protein (more detail) 7 NA Homo sapiens

Pfam MOX011750 Genes associated with Computational Drug Signature CHEMBL76100 Genes associated with Computational Drug Signature CHEMBL76100, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens

DSigDB MOX014469 Genes associated with Computational Drug Signature Phenol, 4,4' (3 methyl 1 butenylidene)bis Genes associated with Computational Drug Signature Phenol, 4,4'-(3-methyl-1-butenylidene)bis-, curat (more detail) 7 25990557 Homo sapiens

DSigDB MOX014637 Genes associated with Computational Drug Signature Prostratin Genes associated with Computational Drug Signature Prostratin, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens

DSigDB TAX014689 GO:0003309 biological process type B pancreatic cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional (more detail) 7 NA Homo sapiens

GOA TAX014770 GO:0003708 molecular function retinoic acid receptor activity Combining with retinoic acid and transmitting the signal to the transcriptional machinery by interac (more detail) 7 NA Homo sapiens

GOA TAX015462 GO:0004887 molecular function thyroid hormone receptor activity Combining with thyroid hormone and transmitting the signal to the transcriptional machinery by inter (more detail) 7 NA Homo sapiens

GOA MOX015778 Genes associated with Computational Drug Signature UNII ZZ6VH5MZ17 Genes associated with Computational Drug Signature UNII-ZZ6VH5MZ17, curated by the Drug Signature Da (more detail) 7 25990557 Homo sapiens

DSigDB MOX017905 Genes associated with Computational Drug Signature Filimarisin Genes associated with Computational Drug Signature Filimarisin, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens

DSigDB GEX001122 migraine disorders migraine disorders associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 7 NA Homo sapiens

GAD FEX001027 Endometrial Salvesen09 11genes Correlations Table S5. Correlations between amplifications and recurrence-free survival (more detail) 7 19261849 Homo sapiens

GeneSigDB WAG000136 Viral dsRNA:TLR3:TRIF Complex Activates RIP1 (more detail) 7 NA Homo sapiens

Reactome GEX001435 restenosis restenosis associated genes. PAGER constructed this gene set by grouping all genes which are associa (more detail) 7 NA Homo sapiens

GAD WAG000477 Cyclin D associated events in G1 (more detail) 7 NA Homo sapiens

Reactome MEX001379 Genes associated with Kinase Inhibitor Kinome 683 Genes associated with Kinase Inhibitor Kinome_683, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MEX001619 Genes associated with Kinase Inhibitor GW410563A Genes associated with Kinase Inhibitor GW410563A, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MEX001824 Genes associated with Kinase Inhibitor Kinome 575 Genes associated with Kinase Inhibitor Kinome_575, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MOX002150 Genes associated with Computational Drug Signature IMIQUIMOD Genes associated with Computational Drug Signature IMIQUIMOD, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MOX006051 Genes associated with Computational Drug Signature 4 cycloheptyliden(4 hydroxyphenyl)methylphenol Genes associated with Computational Drug Signature 4-cycloheptyliden(4-hydroxyphenyl)methylphenol, c (more detail) 7 25990557 Homo sapiens

DSigDB MOX009327 Genes associated with Computational Drug Signature CHEMBL268258 Genes associated with Computational Drug Signature CHEMBL268258, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens

DSigDB MOX012111 Genes associated with Computational Drug Signature Cyclofenil diphenol Genes associated with Computational Drug Signature Cyclofenil diphenol, curated by the Drug Signatur (more detail) 7 25990557 Homo sapiens

DSigDB GEX000830 heroin abuse heroin abuse associated genes. PAGER constructed this gene set by grouping all genes which are assoc (more detail) 7 NA Homo sapiens

GAD WAG000435 tsp 1 induced apoptosis in microvascular endothelial cell As tissues grow they require angiogenesis to occur if they are to be supplied with blood vessels and (more detail) 7 NA Homo sapiens

BioCarta WAG001292 Cholesterol biosynthesis (more detail) 7 NA Homo sapiens

Reactome FEX001361 Leukemia Bal05 07genes Table 4 Expression NF-jB subunits and activating factors in acutely HTLV-1 transformed cells (more detail) 7 15896717 Homo sapiens

GeneSigDB WAG000121 Terminal pathway of complement (more detail) 7 NA Homo sapiens

Reactome MOX001058 Genes associated with Computational Drug Signature Dimethyl phthalate Genes associated with Computational Drug Signature Dimethyl phthalate, curated by the Drug Signature (more detail) 7 25990557 Homo sapiens

DSigDB MEX002065 Genes associated with Kinase Inhibitor Kinome 1078 Genes associated with Kinase Inhibitor Kinome_1078, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MOX000935 Genes associated with Computational Drug Signature TRIETHYLENE GLYCOL DIMETHACRYLATE Genes associated with Computational Drug Signature TRIETHYLENE GLYCOL DIMETHACRYLATE, curated by the (more detail) 7 25990557 Homo sapiens

DSigDB MOX000969 Genes associated with Computational Drug Signature Xanthatin Genes associated with Computational Drug Signature Xanthatin, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MOX006665 Genes associated with Computational Drug Signature AGN PC 001QKA Genes associated with Computational Drug Signature AGN-PC-001QKA, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens

DSigDB WAG001296 Activation of the mRNA upon binding of the cap binding complex and eIFs, and subsequent binding to 43S (more detail) 7 NA Homo sapiens

Reactome GEX001563 tardive dyskinesia tardive dyskinesia associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 7 NA Homo sapiens

GAD MAX000334 Genes up regulated in LNCaP cells (prostate cancer) after knockdown of SAM68 [GeneID=10657] by RNAi. The tyrosine kinase Src is frequently activated in advanced human prostate carcinomas and its activa (more detail) 7 NA Homo sapiens

MSigDB MEX001693 Genes associated with Kinase Inhibitor Kinome 421 Genes associated with Kinase Inhibitor Kinome_421, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MEX002185 Genes associated with Kinase Inhibitor Kinome 507 Genes associated with Kinase Inhibitor Kinome_507, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens

DSigDB MOX001447 Genes associated with Computational Drug Signature Heptafluorobutyric acid Genes associated with Computational Drug Signature Heptafluorobutyric acid, curated by the Drug Sign (more detail) 7 25990557 Homo sapiens

DSigDB MOX000584 Genes associated with Computational Drug Signature DIISONONYL PHTHALATE Genes associated with Computational Drug Signature DIISONONYL PHTHALATE, curated by the Drug Signatu (more detail) 7 25990557 Homo sapiens

DSigDB MOX012970 Genes associated with Computational Drug Signature gw8510 Genes associated with Computational Drug Signature gw8510, curated by the Drug Signature Database (D (more detail) 7 25990557 Homo sapiens

DSigDB TAX013948 GO:0001940 cellular component male pronucleus The pronucleus originating from the spermatozoa that was involved in fertilization. (more detail) 7 NA Homo sapiens

GOA TAX015316 GO:0004679 molecular function AMP activated protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the pres (more detail) 7 NA Homo sapiens

GOA MOX016680 Genes associated with Computational Drug Signature Trilostane Genes associated with Computational Drug Signature Trilostane, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens

DSigDB WIG001944 NLR proteins NLR proteins (more detail) 7 NA Homo sapiens

WikiPathway MEX000448 Genes associated with Approved Drug cysteamine hydrochloride Genes associated with Approved Drug cysteamine hydrochloride, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens

DSigDB MEX001607 Genes associated with Kinase Inhibitor Kinome 41 Genes associated with Kinase Inhibitor Kinome_41, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens