PAGER3: A Pathways, Annotated-lists and Gene signatures Electronic Repository Version 3

Query: biological_process nitrogen compound metabolic process

Result Filters

Size of PAGs

Min

Max

Species

Data Source

PAGs related to the disease: 9259 PAGs

PAG ID	PAG Type	PAG Name	Size	Pubmed Reference	Organism	Data source	cohension

The M-type PAG-PAG relationships

Network Visualization

PAG_A	PAG_A_SIZE	PAG_B	PAG_B_SIZE	Overlap	Similarity score	LOGCDF

The R-type PAG-PAG relationships

Network Visualization

PAG_A	PAG_B	Total	PAG_A_OUT	PAG_B_IN	A regulate B	LOGCDF

Y-U (more detail) 439 NA Homo sapiens

GOA TAX001140 Genes annotated by the GO term GO:0003677. Interacting selectively with DNA (deoxyribonucleic acid). (more detail) 589 NA Homo sapiens

MSigDB TAX013576 GO:0000987 molecular function proximal promoter sequence specific DNA binding Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcr (more detail) 488 NA Homo sapiens

GOA TAX016300 GO:0006397 biological process mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) (more detail) 434 NA Homo sapiens

GOA TAX030822 GO:0097367 molecular function carbohydrate derivative binding Interacting selectively and non-covalently with a carbohydrate derivative. (more detail) 2148 NA Homo sapiens

GOA TAX019726 GO:0019439 biological process aromatic compound catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance (more detail) 454 NA Homo sapiens

GOA TAX019769 GO:0019637 biological process organophosphate metabolic process The chemical reactions and pathways involving organophosphates, any phosphate-containing organic com (more detail) 922 NA Homo sapiens

GOA TAX025717 GO:0046700 biological process heterocycle catabolic process The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with (more detail) 438 NA Homo sapiens

GOA TAX021421 GO:0032268 biological process regulation of cellular protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 2479 NA Homo sapiens

GOA TAX015312 GO:0004674 molecular function protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein (more detail) 453 NA Homo sapiens

GOA FEX000742 Breast Speers09 780genes Supplementary table 1- All kinases used in expression profiling (more detail) 745 19808870 Homo sapiens

GeneSigDB FEX012387 The genes express in medium or high level in at least 95% samples in head and neck cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 3176 28818916 Homo sapiens

HPA-PathologyAtlas TAX013570 GO:0000978 molecular function RNA polymerase II proximal promoter sequence specific DNA binding Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcr (more detail) 468 NA Homo sapiens

GOA TAX032109 GO:1901361 biological process organic cyclic compound catabolic process The chemical reactions and pathways resulting in the breakdown of organic cyclic compound. (more detail) 485 NA Homo sapiens

GOA TAX013651 GO:0001228 molecular function DNA binding transcription activator activity, RNA polymerase II specific A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA (more detail) 411 NA Homo sapiens

GOA MOX004950 Genes associated with Computational Drug Signature cyclosporin A Genes associated with Computational Drug Signature cyclosporin A, curated by the Drug Signature Data (more detail) 4551 25990557 Homo sapiens

DSigDB FEX012390 The genes express in medium or high level in at least 95% samples in thyroid cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 3907 28818916 Homo sapiens

HPA-PathologyAtlas TAX021630 GO:0032553 molecular function ribonucleotide binding Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribon (more detail) 1860 NA Homo sapiens

GOA TAX023000 GO:0035639 molecular function purine ribonucleoside triphosphate binding Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound con (more detail) 1788 NA Homo sapiens

GOA TAX026374 GO:0048856 biological process anatomical structure development The biological process whose specific outcome is the progression of an anatomical structure from an (more detail) 3198 NA Homo sapiens

GOA TAX024195 GO:0043168 molecular function anion binding Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net (more detail) 2688 NA Homo sapiens

GOA TAX026384 GO:0048869 biological process cellular developmental process A biological process whose specific outcome is the progression of a cell over time from an initial c (more detail) 2623 NA Homo sapiens

GOA TAX021632 GO:0032555 molecular function purine ribonucleotide binding Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of (more detail) 1845 NA Homo sapiens

GOA TAX019366 GO:0017076 molecular function purine nucleotide binding Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a pur (more detail) 1856 NA Homo sapiens

GOA TAX026231 GO:0048583 biological process regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to st (more detail) 4003 NA Homo sapiens

GOA TAX022590 GO:0034655 biological process nucleobase containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleoti (more detail) 394 NA Homo sapiens

GOA FEX000990 EmbryonicStemCell Thomas08 839genes Supplementary Table 5. Genes annotated as involved in transcription regulation common to both hNCC a (more detail) 768 18689800 Homo sapiens

GeneSigDB TAX000656 Genes annotated by the GO term GO:0019219. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. (more detail) 607 NA Homo sapiens

MSigDB TAX030032 GO:0072521 biological process purine containing compound metabolic process The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that c (more detail) 388 NA Homo sapiens

GOA TAX016256 GO:0006325 biological process chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of (more detail) 607 NA Homo sapiens

GOA FEX012447 The normalized gene expressions no less than 30 in the tissue of skeletal muscle. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 3023 25613900 Homo sapiens

HPA-RNAcon FEX002230 Lymphoma Melendez05 4229genes SuppTable 1. This file contains row genomic and expression data for each gene. Each gene is identifi (more detail) 2478 15656903 Homo sapiens

GeneSigDB TAX034390 GO:1990904 cellular component ribonucleoprotein complex A macromolecular complex containing both protein and RNA molecules. (more detail) 812 NA Homo sapiens

GOA MOX004342 Genes associated with Computational Drug Signature METHYL METHANESULFONATE Genes associated with Computational Drug Signature METHYL METHANESULFONATE, curated by the Drug Sign (more detail) 3627 25990557 Homo sapiens

DSigDB MOX000853 Genes associated with Computational Drug Signature 7646 79 9 Genes associated with Computational Drug Signature 7646-79-9, curated by the Drug Signature Database (more detail) 2952 25990557 Homo sapiens

DSigDB TAX032021 GO:1901137 biological process carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative. (more detail) 443 NA Homo sapiens

GOA FEX003014 StemCell Nilsson07 3742genes Table S1. Genes sorted as up-regulated and down-regulated in normal CD34+CD38?Thy-1+ stem cells com (more detail) 3280 17616640 Homo sapiens

GeneSigDB TAX029699 GO:0071840 biological process cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of c (more detail) 4929 NA Homo sapiens

GOA IEI014105 Protein protein interactors of human gene TP53 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TP53 (SwissProt ID=P (more detail) 950 17535438 Homo sapiens

I2D TAX000646 Genes annotated by the GO term GO:0019222. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. (more detail) 785 NA Homo sapiens

MSigDB TAX000682 Genes annotated by the GO term GO:0045449. Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. (more detail) 556 NA Homo sapiens

MSigDB TAX017231 GO:0008380 biological process RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in th (more detail) 369 NA Homo sapiens

GOA TAX017080 GO:0008134 molecular function transcription factor binding Interacting selectively and non-covalently with a transcription factor, any protein required to init (more detail) 596 NA Homo sapiens

GOA TAX000530 Genes annotated by the GO term GO:0043687. The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome. (more detail) 462 NA Homo sapiens

MSigDB TAX020341 GO:0030163 biological process protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of th (more detail) 368 NA Homo sapiens

GOA MAX002337 Genes constituting the BRCA1 PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient, PCC >= 0.4) with that of BRCA1 [GeneID=672] across a compendium of normal tissues. Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms (more detail) 1554 NA Homo sapiens

MSigDB FEX002890 StemCell Bhattacharya05 2843genes Supplementary Table 1Sa. Overexpression of genes ( (more detail) 2352 16207381 Homo sapiens

GeneSigDB TAX018835 GO:0016043 biological process cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellul (more detail) 4875 NA Homo sapiens

GOA TAX000596 Genes annotated by the GO term GO:0031323. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. (more detail) 773 NA Homo sapiens

MSigDB TAX000790 Genes annotated by the GO term GO:0006366. The synthesis of RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). (more detail) 444 NA Homo sapiens

MSigDB TAX013574 GO:0000982 molecular function transcription factor activity, RNA polymerase II proximal promoter sequence specific DNA binding Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively (more detail) 402 NA Homo sapiens

GOA TAX019779 GO:0019693 biological process ribose phosphate metabolic process The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar. (more detail) 368 NA Homo sapiens

GOA TAX016117 GO:0006082 biological process organic acid metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon i (more detail) 940 NA Homo sapiens

GOA TAX024504 GO:0043687 biological process post translational protein modification The process of covalently altering one or more amino acids in a protein after the protein has been c (more detail) 362 NA Homo sapiens

GOA TAX019095 GO:0016569 biological process covalent chromatin modification The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups (more detail) 362 NA Homo sapiens

GOA TAX014771 GO:0003712 molecular function transcription coregulator activity A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound D (more detail) 544 NA Homo sapiens

GOA FEX002708 Manning02 624genes ProteinKinases protein kinases : The protein kinase complement of the human genome (more detail) 363 12471243 Homo sapiens

GeneSigDB TAX016160 GO:0006163 biological process purine nucleotide metabolic process The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleosi (more detail) 354 NA Homo sapiens

GOA TAX023723 GO:0042221 biological process response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 2510 NA Homo sapiens

GOA TAX019096 GO:0016570 biological process histone modification The covalent alteration of one or more amino acid residues within a histone protein. (more detail) 352 NA Homo sapiens

GOA TAX024369 GO:0043436 biological process oxoacid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains o (more detail) 924 NA Homo sapiens

GOA TAX017636 GO:0009259 biological process ribonucleotide metabolic process The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleos (more detail) 351 NA Homo sapiens

GOA TAX020333 GO:0030154 biological process cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire s (more detail) 1791 NA Homo sapiens

GOA TAX000621 Genes annotated by the GO term GO:0010468. Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. (more detail) 659 NA Homo sapiens

MSigDB FEX012451 The normalized gene expressions no less than 30 in the tissue of thymus. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1790 25613900 Homo sapiens

HPA-RNAcon FEX012585 The normalized gene expressions no less than 30 in the tissue of thymus from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1790 25613900 Homo sapiens

HPA-FANTOM5 TAX016387 GO:0006518 biological process peptide metabolic process The chemical reactions and pathways involving peptides, compounds of two or more amino acids where t (more detail) 345 NA Homo sapiens

GOA TAX031706 GO:0140098 molecular function catalytic activity, acting on RNA Catalytic activity that acts to modify RNA. (more detail) 361 NA Homo sapiens

GOA FEX000341 Breast Reyal05 3373genesSuppTable2SuppTable2 Table 2: Complete list of genes for which the TC score is above the threshold for the transcription (more detail) 2855 15735024 Homo sapiens

GeneSigDB TAX019124 GO:0016604 cellular component nuclear body Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies (more detail) 728 NA Homo sapiens

GOA TAX017548 GO:0009150 biological process purine ribonucleotide metabolic process The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribo (more detail) 336 NA Homo sapiens

GOA TAX000677 Genes annotated by the GO term GO:0051252. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. (more detail) 463 NA Homo sapiens

MSigDB TAX022513 GO:0034470 biological process ncRNA processing Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts (more detail) 335 NA Homo sapiens

GOA FEX000791 Breast Walker10 3588genes SuppTable 1. List of genes and their associated significance levels from three different analyses. (more detail) 2815 20174566 Homo sapiens

GeneSigDB TAX024743 GO:0044427 cellular component chromosomal part Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associ (more detail) 795 NA Homo sapiens

GOA TAX000683 Genes annotated by the GO term GO:0006355. Any process that modulates the frequency, rate or extent of DNA dependent transcription. (more detail) 453 NA Homo sapiens

MSigDB IEI006058 Protein protein interactors of human gene HSP90AA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSP90AA1 (SwissProt (more detail) 831 17535438 Homo sapiens

I2D FAX000286 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif GGGCGGR which matches annotation for SP1: Sp1 transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif GGGCGGR (more detail) 2720 NA Homo sapiens

MSigDB FEX012428 The normalized gene expressions no less than 30 in the tissue of liver. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 2824 25613900 Homo sapiens

HPA-RNAcon IEI006060 Protein protein interactors of human gene HSP90AB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSP90AB1 (SwissProt (more detail) 703 17535438 Homo sapiens

I2D TAX024468 GO:0043604 biological process amide biosynthetic process The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxo (more detail) 328 NA Homo sapiens

GOA TAX030184 GO:0080134 biological process regulation of response to stress Any process that modulates the frequency, rate or extent of a response to stress. Response to stress (more detail) 1361 NA Homo sapiens

GOA FEX012491 The normalized gene expressions no less than 30 in the tissue of bone marrow from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1850 25613900 Homo sapiens

HPA-normRNA FEX012434 The normalized gene expressions no less than 30 in the tissue of bone marrow. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1850 25613900 Homo sapiens

HPA-RNAcon MOX004120 Genes associated with Computational Drug Signature formaldehyde Genes associated with Computational Drug Signature formaldehyde, curated by the Drug Signature Datab (more detail) 3006 25990557 Homo sapiens

DSigDB TAX027163 GO:0051726 biological process regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle. (more detail) 1114 NA Homo sapiens

GOA TAX026894 GO:0051247 biological process positive regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 1570 NA Homo sapiens

GOA TAX020229 GO:0023014 biological process signal transduction by protein phosphorylation A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to (more detail) 319 NA Homo sapiens

GOA MOX004785 Genes associated with Computational Drug Signature Retinoic acid Genes associated with Computational Drug Signature Retinoic acid, curated by the Drug Signature Data (more detail) 4092 25990557 Homo sapiens

DSigDB TAX026858 GO:0051186 biological process cofactor metabolic process The chemical reactions and pathways involving a cofactor, a substance that is required for the activ (more detail) 476 NA Homo sapiens

GOA FEX012386 The genes express in medium or high level in at least 95% samples in colorectal cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 3023 28818916 Homo sapiens

HPA-PathologyAtlas FEX002891 StemCell Bhattacharya05 2471genes Supplementary Table 1Sb. Over expression of genes ( (more detail) 1986 16207381 Homo sapiens

GeneSigDB IEI013212 Protein protein interactors of human gene SUMO3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUMO3 (SwissProt ID= (more detail) 864 17535438 Homo sapiens

I2D WIG000868 Genes involved in Generic Transcription Pathway (more detail) 336 NA Homo sapiens

MSigDB TAX020967 GO:0031399 biological process regulation of protein modification process Any process that modulates the frequency, rate or extent of the covalent alteration of one or more a (more detail) 1744 NA Homo sapiens

GOA TAX026232 GO:0048584 biological process positive regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to a stimulus. Response to (more detail) 2173 NA Homo sapiens

GOA TAX017841 GO:0010033 biological process response to organic substance Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 2019 NA Homo sapiens

GOA TAX014758 GO:0003682 molecular function chromatin binding Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, an (more detail) 482 NA Homo sapiens

GOA IEI004187 Protein protein interactors of human gene EP300 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EP300 (SwissProt ID= (more detail) 548 17535438 Homo sapiens

I2D FEX012538 The normalized gene expressions no less than 30 in the tissue of skeletal muscle from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 2206 25613900 Homo sapiens

HPA-GTEx MOX004729 Genes associated with Computational Drug Signature Tetradioxin Genes associated with Computational Drug Signature Tetradioxin, curated by the Drug Signature Databa (more detail) 3601 25990557 Homo sapiens

DSigDB IEI005748 Protein protein interactors of human gene HDAC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDAC1 (SwissProt ID= (more detail) 591 17535438 Homo sapiens

I2D TAX024237 GO:0043228 cellular component non membrane bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. (more detail) 2397 NA Homo sapiens

GOA IEI013209 Protein protein interactors of human gene SUMO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUMO1 (SwissProt ID= (more detail) 1010 17535438 Homo sapiens

I2D TAX024241 GO:0043232 cellular component intracellular non membrane bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane (more detail) 2386 NA Homo sapiens

GOA TAX021423 GO:0032270 biological process positive regulation of cellular protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 1481 NA Homo sapiens

GOA TAX026890 GO:0051239 biological process regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of a multicellular organismal process, the (more detail) 2813 NA Homo sapiens

GOA FEX003015 StemCell Nilsson07 3153genes Table S3. Genes ranked by differential expression in 5q- CD34+CD38?Thy-1+ stem cells compared to no (more detail) 2745 17616640 Homo sapiens

GeneSigDB MOX003614 Genes associated with Computational Drug Signature acetaminophen Genes associated with Computational Drug Signature acetaminophen, curated by the Drug Signature Data (more detail) 3910 25990557 Homo sapiens

DSigDB TAX026595 GO:0050793 biological process regulation of developmental process Any process that modulates the frequency, rate or extent of development, the biological process whos (more detail) 2368 NA Homo sapiens

GOA MOX004199 Genes associated with Computational Drug Signature hydrogen peroxide Genes associated with Computational Drug Signature hydrogen peroxide, curated by the Drug Signature (more detail) 2527 25990557 Homo sapiens

DSigDB MEX002069 Genes associated with Kinase Inhibitor staurosporine Genes associated with Kinase Inhibitor staurosporine, curated by the Drug Signature Database (DSigDB (more detail) 313 25990557 Homo sapiens

DSigDB TAX013286 GO:0000165 biological process MAPK cascade An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade (more detail) 294 NA Homo sapiens

GOA TAX001431 Genes annotated by the GO term GO:0016772. Catalysis of the transfer of a phosphorus containing group from one compound (donor) to another (acceptor). (more detail) 419 NA Homo sapiens

MSigDB TAX030478 GO:0090305 biological process nucleic acid phosphodiester bond hydrolysis The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved (more detail) 292 NA Homo sapiens

GOA MEX003310 Genes associated with Perturbagen Signature H 7 Genes associated with Perturbagen Signature H-7, curated by the Drug Signature Database (DSigDB). (more detail) 1620 25990557 Homo sapiens

DSigDB TAX016598 GO:0006790 biological process sulfur compound metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that conta (more detail) 352 NA Homo sapiens

GOA TAX025806 GO:0046914 molecular function transition metal ion binding Interacting selectively and non-covalently with a transition metal ions; a transition metal is an el (more detail) 1053 NA Homo sapiens

GOA TAX018238 GO:0010941 biological process regulation of cell death Any process that modulates the rate or frequency of cell death. Cell death is the specific activatio (more detail) 1606 NA Homo sapiens

GOA MEX002765 Genes associated with Perturbagen Signature camptothecin Genes associated with Perturbagen Signature camptothecin, curated by the Drug Signature Database (DS (more detail) 1839 25990557 Homo sapiens

DSigDB TAX016388 GO:0006520 biological process cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more a (more detail) 288 NA Homo sapiens

GOA TAX019404 GO:0017144 biological process drug metabolic process The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment o (more detail) 538 NA Homo sapiens

GOA TAX019796 GO:0019752 biological process carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or m (more detail) 838 NA Homo sapiens

GOA TAX029047 GO:0070646 biological process protein modification by small protein removal A protein modification process in which one or more covalently attached groups of a small protein, s (more detail) 285 NA Homo sapiens

GOA TAX019871 GO:0019899 molecular function enzyme binding Interacting selectively and non-covalently with any enzyme. (more detail) 2186 NA Homo sapiens

GOA TAX015890 GO:0005730 cellular component nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich (more detail) 830 NA Homo sapiens

GOA TAX017144 GO:0008236 molecular function serine type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that in (more detail) 281 NA Homo sapiens

GOA FEX012389 The genes express in medium or high level in at least 95% samples in testis cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1892 28818916 Homo sapiens

HPA-PathologyAtlas TAX024765 GO:0044454 cellular component nuclear chromosome part Any constituent part of a nuclear chromosome, a chromosome that encodes the nuclear genome and is fo (more detail) 472 NA Homo sapiens

GOA TAX017939 GO:0010498 biological process proteasomal protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 279 NA Homo sapiens

GOA MOX004611 Genes associated with Computational Drug Signature quercetin Genes associated with Computational Drug Signature quercetin, curated by the Drug Signature Database (more detail) 3000 25990557 Homo sapiens

DSigDB FEX012582 The normalized gene expressions no less than 30 in the tissue of skeletal muscle from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1988 25613900 Homo sapiens

HPA-FANTOM5 IEI004302 Protein protein interactors of human gene ESR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ESR1 (SwissProt ID=P (more detail) 743 17535438 Homo sapiens

I2D FEX012567 The normalized gene expressions no less than 30 in the tissue of liver from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 2338 25613900 Homo sapiens

HPA-FANTOM5 MOX004058 Genes associated with Computational Drug Signature estradiol Genes associated with Computational Drug Signature estradiol, curated by the Drug Signature Database (more detail) 4154 25990557 Homo sapiens

DSigDB TAX019423 GO:0017171 molecular function serine hydrolase activity Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad (more detail) 286 NA Homo sapiens

GOA TAX001421 Genes annotated by the GO term GO:0003700. The function of binding to a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. (more detail) 349 NA Homo sapiens

MSigDB MAX000642 Genes up regulated in CD34+ [GeneID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients, compared to those from normal donors. In this study, we provide a molecular signature of highly enriched CD34+ cells from bone marrow of u (more detail) 1314 NA Homo sapiens

MSigDB TAX024140 GO:0043067 biological process regulation of programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death, cell death result (more detail) 1492 NA Homo sapiens

GOA TAX019218 GO:0016788 molecular function hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond. (more detail) 752 NA Homo sapiens

GOA TAX000988 Genes annotated by the GO term GO:0044428. Any constituent part of the nucleus, a membrane bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. (more detail) 555 NA Homo sapiens

MSigDB TAX022935 GO:0035556 biological process intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become ac (more detail) 1481 NA Homo sapiens

GOA TAX013604 GO:0001077 molecular function proximal promoter DNA binding transcription activator activity, RNA polymerase II specific A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA (more detail) 272 NA Homo sapiens

GOA MOX003727 Genes associated with Computational Drug Signature benzo[a]pyrene Genes associated with Computational Drug Signature benzo[a]pyrene, curated by the Drug Signature Dat (more detail) 4201 25990557 Homo sapiens

DSigDB MAX002336 Genes constituting the ATM PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient, PCC >= 0.4) with that of ATM [GeneID=472] across a compendium of normal tissues. Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms (more detail) 1376 NA Homo sapiens

MSigDB TAX019105 GO:0016579 biological process protein deubiquitination The removal of one or more ubiquitin groups from a protein. (more detail) 269 NA Homo sapiens

GOA TAX023681 GO:0042127 biological process regulation of cell proliferation Any process that modulates the frequency, rate or extent of cell proliferation. (more detail) 1570 NA Homo sapiens

GOA MEX003090 Genes associated with Perturbagen Signature doxorubicin Genes associated with Perturbagen Signature doxorubicin, curated by the Drug Signature Database (DSi (more detail) 1289 25990557 Homo sapiens

DSigDB TAX024081 GO:0042981 biological process regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process. (more detail) 1475 NA Homo sapiens

GOA TAX017162 GO:0008270 molecular function zinc ion binding Interacting selectively and non-covalently with zinc (Zn) ions. (more detail) 801 NA Homo sapiens

GOA TAX032078 GO:1901293 biological process nucleoside phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside phosphate. (more detail) 264 NA Homo sapiens

GOA IEI003159 Protein protein interactors of human gene CUL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUL3 (SwissProt ID=Q (more detail) 1145 17535438 Homo sapiens

I2D TAX017562 GO:0009165 biological process nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that i (more detail) 262 NA Homo sapiens

GOA MEX002576 Genes associated with Perturbagen Signature alsterpaullone Genes associated with Perturbagen Signature alsterpaullone, curated by the Drug Signature Database ( (more detail) 1676 25990557 Homo sapiens

DSigDB MEX003308 Genes associated with Perturbagen Signature GW 8510 Genes associated with Perturbagen Signature GW-8510, curated by the Drug Signature Database (DSigDB) (more detail) 1607 25990557 Homo sapiens

DSigDB TAX015859 GO:0005667 cellular component transcription factor complex A protein complex that is capable of associating with DNA by direct binding, or via other DNA-bindin (more detail) 327 NA Homo sapiens

GOA TAX030531 GO:0090407 biological process organophosphate biosynthetic process The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phos (more detail) 546 NA Homo sapiens

GOA TAX024191 GO:0043161 biological process proteasome mediated ubiquitin dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 257 NA Homo sapiens

GOA TAX019492 GO:0018205 biological process peptidyl lysine modification The modification of peptidyl-lysine. (more detail) 256 NA Homo sapiens

GOA TAX029166 GO:0070887 biological process cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 1531 NA Homo sapiens

GOA IEI002974 Protein protein interactors of human gene CREBBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CREBBP (SwissProt ID (more detail) 373 17535438 Homo sapiens

I2D TAX025154 GO:0045595 biological process regulation of cell differentiation Any process that modulates the frequency, rate or extent of cell differentiation, the process in whi (more detail) 1647 NA Homo sapiens

GOA TAX013381 GO:0000375 biological process RNA splicing, via transesterification reactions Splicing of RNA via a series of two transesterification reactions. (more detail) 253 NA Homo sapiens

GOA FEX012384 The genes express in medium or high level in at least 95% samples in breast cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 2190 28818916 Homo sapiens

HPA-PathologyAtlas MEX002974 Genes associated with Perturbagen Signature daunorubicin Genes associated with Perturbagen Signature daunorubicin, curated by the Drug Signature Database (DS (more detail) 1454 25990557 Homo sapiens

DSigDB MAX000198 Genes up regulated in brain from patients with Alzheimer's disease. The pathogenesis of incipient Alzheimer's disease (AD) has been resistant to analysis because of the (more detail) 1606 NA Homo sapiens

MSigDB MEX002285 Genes associated with Kinase Inhibitor Lestaurtinib Genes associated with Kinase Inhibitor Lestaurtinib, curated by the Drug Signature Database (DSigDB) (more detail) 270 25990557 Homo sapiens

DSigDB TAX015037 GO:0004252 molecular function serine type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic m (more detail) 251 NA Homo sapiens

GOA FEX012498 The normalized gene expressions no less than 30 in the tissue of skeletal muscle from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 2201 25613900 Homo sapiens

HPA-normRNA TAX017820 GO:0009966 biological process regulation of signal transduction Any process that modulates the frequency, rate or extent of signal transduction. (more detail) 3036 NA Homo sapiens

GOA TAX034435 GO:2000026 biological process regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of multicellular organismal development. (more detail) 1833 NA Homo sapiens

GOA TAX001221 Genes annotated by the GO term GO:0016301. Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. (more detail) 364 NA Homo sapiens

MSigDB TAX013393 GO:0000398 biological process mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the e (more detail) 248 NA Homo sapiens

GOA TAX013382 GO:0000377 biological process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue fr (more detail) 248 NA Homo sapiens

GOA FEX001762 Liver Tzur09 1908genes Table S5. Differentially-expressed genes throughout development; Multiple genes were significantly ( (more detail) 1410 19841744 Homo sapiens

GeneSigDB MEX000996 Genes associated with Approved Drug sunitinib Genes associated with Approved Drug sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 256 25990557 Homo sapiens

DSigDB FEX012442 The normalized gene expressions no less than 30 in the tissue of ovary. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1511 25613900 Homo sapiens

HPA-RNAcon TAX025851 GO:0046983 molecular function protein dimerization activity The formation of a protein dimer, a macromolecular structure consists of two noncovalently associate (more detail) 1188 NA Homo sapiens

GOA FEX012489 The normalized gene expressions no less than 30 in the tissue of liver from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1997 25613900 Homo sapiens

HPA-normRNA FEX000992 EmbryonicStemCell Thomas08 1088genes Supplementary Table 7. hNCC and hES commonly expressed genes involved in cell proliferation; hNCC tp (more detail) 998 18689800 Homo sapiens

GeneSigDB IEI008723 Protein protein interactors of human gene NEDD8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEDD8 (SwissProt ID= (more detail) 1043 17535438 Homo sapiens

I2D MEX002888 Genes associated with Perturbagen Signature clindamycin Genes associated with Perturbagen Signature clindamycin, curated by the Drug Signature Database (DSi (more detail) 1553 25990557 Homo sapiens

DSigDB TAX026195 GO:0048513 biological process animal organ development Development of a tissue or tissues that work together to perform a specific function or functions. D (more detail) 1185 NA Homo sapiens

GOA TAX024027 GO:0042802 molecular function identical protein binding Interacting selectively and non-covalently with an identical protein or proteins. (more detail) 1636 NA Homo sapiens

GOA MOX004073 Genes associated with Computational Drug Signature ETHYL METHANESULFONATE Genes associated with Computational Drug Signature ETHYL METHANESULFONATE, curated by the Drug Signa (more detail) 2191 25990557 Homo sapiens

DSigDB IEI002853 Protein protein interactors of human gene COPS5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COPS5 (SwissProt ID= (more detail) 781 17535438 Homo sapiens

I2D TAX018027 GO:0010646 biological process regulation of cell communication Any process that modulates the frequency, rate or extent of cell communication. Cell communication i (more detail) 3375 NA Homo sapiens

GOA MEX001673 Genes associated with Kinase Inhibitor SureCN1564574 Genes associated with Kinase Inhibitor SureCN1564574, curated by the Drug Signature Database (DSigDB (more detail) 254 25990557 Homo sapiens

DSigDB TAX020240 GO:0023051 biological process regulation of signaling Any process that modulates the frequency, rate or extent of a signaling process. (more detail) 3402 NA Homo sapiens

GOA TAX028676 GO:0065009 biological process regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biolo (more detail) 3093 NA Homo sapiens

GOA TAX013278 GO:0000151 cellular component ubiquitin ligase complex A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase acti (more detail) 304 NA Homo sapiens

GOA TAX001329 Genes annotated by the GO term GO:0004672. Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. (more detail) 281 NA Homo sapiens

MSigDB TAX013304 GO:0000209 biological process protein polyubiquitination Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. (more detail) 237 NA Homo sapiens

GOA TAX016304 GO:0006401 biological process RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the (more detail) 237 NA Homo sapiens

GOA TAX024242 GO:0043233 cellular component organelle lumen The internal volume enclosed by the membranes of a particular organelle; includes the volume enclose (more detail) 1199 NA Homo sapiens

GOA TAX021260 GO:0031974 cellular component membrane enclosed lumen The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume (more detail) 1199 NA Homo sapiens

GOA TAX028687 GO:0070013 cellular component intracellular organelle lumen An organelle lumen that is part of an intracellular organelle. (more detail) 1199 NA Homo sapiens

GOA TAX028530 GO:0061659 molecular function ubiquitin like protein ligase activity Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction (more detail) 236 NA Homo sapiens

GOA MAX000568 Genes whose promoters are bound by MYC [GeneID=4609], according to MYC Target Gene Database. We report a database of genes responsive to the Myc oncogenic transcription factor. The database Myc (more detail) 1023 NA Homo sapiens

MSigDB MOX000847 Genes associated with Computational Drug Signature Arsenenous acid Genes associated with Computational Drug Signature Arsenenous acid, curated by the Drug Signature Da (more detail) 1244 25990557 Homo sapiens

DSigDB MEX004322 Genes associated with Perturbagen Signature trichostatin A Genes associated with Perturbagen Signature trichostatin A, curated by the Drug Signature Database ( (more detail) 1486 25990557 Homo sapiens

DSigDB TAX016365 GO:0006486 biological process protein glycosylation A protein modification process that results in the addition of a carbohydrate or carbohydrate deriva (more detail) 233 NA Homo sapiens

GOA TAX024355 GO:0043413 biological process macromolecule glycosylation The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polyn (more detail) 233 NA Homo sapiens

GOA TAX028675 GO:0065008 biological process regulation of biological quality Any process that modulates a qualitative or quantitative trait of a biological quality. A biological (more detail) 3367 NA Homo sapiens

GOA MOX003704 Genes associated with Computational Drug Signature atrazine Genes associated with Computational Drug Signature atrazine, curated by the Drug Signature Database (more detail) 2827 25990557 Homo sapiens

DSigDB TAX028518 GO:0061630 molecular function ubiquitin protein ligase activity Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X (more detail) 231 NA Homo sapiens

GOA IEI005751 Protein protein interactors of human gene HDAC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDAC2 (SwissProt ID= (more detail) 404 17535438 Homo sapiens

I2D MOX002245 Genes associated with Computational Drug Signature resveratrol Genes associated with Computational Drug Signature resveratrol, curated by the Drug Signature Databa (more detail) 1552 25990557 Homo sapiens

DSigDB TAX026849 GO:0051174 biological process regulation of phosphorus metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 1662 NA Homo sapiens

GOA TAX001003 Genes annotated by the GO term GO:0043233. The volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear membrane lumen. (more detail) 437 NA Homo sapiens

MSigDB TAX000945 Genes annotated by the GO term GO:0031974. The enclosed volume within a sealed membrane or between two sealed membranes. (more detail) 437 NA Homo sapiens

MSigDB FEX012385 The genes express in medium or high level in at least 95% samples in carcinoid. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 2147 28818916 Homo sapiens

HPA-PathologyAtlas TAX026951 GO:0051338 biological process regulation of transferase activity Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of t (more detail) 943 NA Homo sapiens

GOA IEI008418 Protein protein interactors of human gene MYC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYC (SwissProt ID=P0 (more detail) 993 17535438 Homo sapiens

I2D TAX019645 GO:0019220 biological process regulation of phosphate metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 1660 NA Homo sapiens

GOA FAX000285 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif GGGAGGRR which matches annotation for MAZ: MYC associated zinc finger protein (purine binding transcription factor) Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif GGGAGGRR (more detail) 2120 NA Homo sapiens

MSigDB FEX012535 The normalized gene expressions no less than 30 in the tissue of liver from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 1763 25613900 Homo sapiens

HPA-GTEx TAX024356 GO:0043414 biological process macromolecule methylation The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynuc (more detail) 226 NA Homo sapiens

GOA FEX012463 The normalized gene expressions no less than 30 in the tissue of cerebellum. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1805 25613900 Homo sapiens

HPA-RNAcon FEX012379 The genes express in medium or high level in at least 95% samples in ovarian cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1721 28818916 Homo sapiens

HPA-PathologyAtlas TAX001422 Genes annotated by the GO term GO:0008134. Interacting selectively with a transcription factor, any protein required to initiate or regulate transcription. (more detail) 304 NA Homo sapiens

MSigDB FEX000116 BoneMarrow Zhan07 2181genes Table S1. Genes significantly differentially expressed between NPC and MGUS (more detail) 1533 17023574 Homo sapiens

GeneSigDB FEX012394 The genes express in medium or high level in at least 95% samples in melanoma. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1663 28818916 Homo sapiens

HPA-PathologyAtlas TAX028722 GO:0070085 biological process glycosylation The covalent attachment and further modification of carbohydrate residues to a substrate molecule. (more detail) 244 NA Homo sapiens

GOA MEX002615 Genes associated with Perturbagen Signature anisomycin Genes associated with Perturbagen Signature anisomycin, curated by the Drug Signature Database (DSig (more detail) 1653 25990557 Homo sapiens

DSigDB TAX015196 GO:0004518 molecular function nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids. (more detail) 221 NA Homo sapiens

GOA TAX001314 Genes annotated by the GO term GO:0016773. Catalysis of the transfer of a phosphorus containing group from one compound (donor) to an alcohol group (acceptor). (more detail) 329 NA Homo sapiens

MSigDB MAX002343 Genes constituting the CHEK2 PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient, PCC >= 0.4) with that of CHEK2 [GeneID=11200]. Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms (more detail) 737 NA Homo sapiens

MSigDB FEX003128 StemCell Majeti09 3024genes Dataset (ST3). 3 005 differentially expressed genes with 1 451 genes being up-regulated and 1 554 ge (more detail) 2552 19218430 Homo sapiens

GeneSigDB FEX000354 Breast Farmer05 3198genes basal apocrine luminal most discriminant genes by Wilcoxon test for each pairwise comparison in our data (luminal vs basal (more detail) 2895 15897907 Homo sapiens

GeneSigDB FEX000523 Breast Larsson07 3085genes Supplementary table 2. Translationally regulated genes. (more detail) 1977 17638893 Homo sapiens

GeneSigDB FEX001461 Leukemia Yukinawa06 2000genes SuppTable1. Contains all gene expression data. (more detail) 1421 16872506 Homo sapiens

GeneSigDB TAX016559 GO:0006732 biological process coenzyme metabolic process The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors (more detail) 303 NA Homo sapiens

GOA FEX003154 StemCell Hassan09 1544genes Supplementary Table 3. Gene list mapped to the Affymetrix Human Genome U133A focusing on gene sets (more detail) 1040 19808871 Homo sapiens

GeneSigDB MEX003462 Genes associated with Perturbagen Signature latamoxef Genes associated with Perturbagen Signature latamoxef, curated by the Drug Signature Database (DSigD (more detail) 1497 25990557 Homo sapiens

DSigDB TAX018851 GO:0016072 biological process rRNA metabolic process The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribos (more detail) 217 NA Homo sapiens

GOA TAX024128 GO:0043043 biological process peptide biosynthetic process The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more ( (more detail) 217 NA Homo sapiens

GOA MEX001467 Genes associated with Kinase Inhibitor OTSSP167 Genes associated with Kinase Inhibitor OTSSP167, curated by the Drug Signature Database (DSigDB). (more detail) 234 25990557 Homo sapiens

DSigDB MEX003408 Genes associated with Perturbagen Signature irinotecan Genes associated with Perturbagen Signature irinotecan, curated by the Drug Signature Database (DSig (more detail) 1466 25990557 Homo sapiens

DSigDB TAX000925 Genes annotated by the GO term GO:0044446. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane. (more detail) 1141 NA Homo sapiens

MSigDB MEX003494 Genes associated with Perturbagen Signature lobeline Genes associated with Perturbagen Signature lobeline, curated by the Drug Signature Database (DSigDB (more detail) 1442 25990557 Homo sapiens

DSigDB IEI003157 Protein protein interactors of human gene CUL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUL1 (SwissProt ID=Q (more detail) 629 17535438 Homo sapiens

I2D FEX012536 The normalized gene expressions no less than 30 in the tissue of ovary from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 1019 25613900 Homo sapiens

HPA-GTEx TAX023777 GO:0042325 biological process regulation of phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into a mole (more detail) 1465 NA Homo sapiens

GOA TAX001006 Genes annotated by the GO term GO:0044422. Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane. (more detail) 1146 NA Homo sapiens

MSigDB IEI004077 Protein protein interactors of human gene ELAVL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELAVL1 (SwissProt ID (more detail) 1804 17535438 Homo sapiens

I2D TAX000984 Genes annotated by the GO term GO:0031981. The volume enclosed by the nuclear inner membrane. (more detail) 370 NA Homo sapiens

MSigDB TAX020969 GO:0031401 biological process positive regulation of protein modification process Any process that activates or increases the frequency, rate or extent of the covalent alteration of (more detail) 1136 NA Homo sapiens

GOA IEI001421 Protein protein interactors of human gene BRCA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRCA1 (SwissProt ID= (more detail) 538 17535438 Homo sapiens

I2D TAX000685 Genes annotated by the GO term GO:0006357. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. (more detail) 281 NA Homo sapiens

MSigDB FEX012404 The genes express in the subcellular location of nucleoplasm. Subcellular location of proteins based on immunofluorescently stained cells. The tab-separated file (more detail) 2962 28495876 Homo sapiens

HPA-CellAtlas MOX001817 Genes associated with Computational Drug Signature 2 Methylcholine Genes associated with Computational Drug Signature 2-Methylcholine, curated by the Drug Signature Da (more detail) 1608 25990557 Homo sapiens

DSigDB TAX024663 GO:0044283 biological process small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of small molecules, any low molecular (more detail) 567 NA Homo sapiens

GOA TAX029378 GO:0071310 biological process cellular response to organic substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 1251 NA Homo sapiens

GOA MOX004844 Genes associated with Computational Drug Signature VITAMIN E Genes associated with Computational Drug Signature VITAMIN E, curated by the Drug Signature Database (more detail) 1448 25990557 Homo sapiens

DSigDB TAX016305 GO:0006402 biological process mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is resp (more detail) 207 NA Homo sapiens

GOA TAX017798 GO:0009894 biological process regulation of catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways res (more detail) 844 NA Homo sapiens

GOA TAX014362 GO:0002682 biological process regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune system process. (more detail) 1475 NA Homo sapiens

GOA TAX032180 GO:1901605 biological process alpha amino acid metabolic process The chemical reactions and pathways involving an alpha-amino acid. (more detail) 206 NA Homo sapiens

GOA FOX000857 Genes in the cancer module 98 (more detail) 377 NA Homo sapiens

MSigDB TAX021416 GO:0032259 biological process methylation The process in which a methyl group is covalently attached to a molecule. (more detail) 286 NA Homo sapiens

GOA TAX027095 GO:0051604 biological process protein maturation Any process leading to the attainment of the full functional capacity of a protein. (more detail) 204 NA Homo sapiens

GOA FEX001146 Immune Kong10 2491genes ImmPort CD40LandAnti IgMvsControl ImmPort genelist of B Cell Stimulation: CD40L and Anti-IgM vs. Control (more detail) 1515 20460173 Homo sapiens

GeneSigDB MEX004114 Genes associated with Perturbagen Signature scriptaid Genes associated with Perturbagen Signature scriptaid, curated by the Drug Signature Database (DSigD (more detail) 984 25990557 Homo sapiens

DSigDB IEI001764 Protein protein interactors of human gene CAND1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAND1 (SwissProt ID= (more detail) 638 17535438 Homo sapiens

I2D TAX016353 GO:0006470 biological process protein dephosphorylation The process of removing one or more phosphoric residues from a protein. (more detail) 203 NA Homo sapiens

GOA MOX001842 Genes associated with Computational Drug Signature ( ) Epigallocatechin gallate Genes associated with Computational Drug Signature (-)-Epigallocatechin gallate, curated by the Drug (more detail) 2014 25990557 Homo sapiens

DSigDB TAX014772 GO:0003713 molecular function transcription coactivator activity A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound D (more detail) 304 NA Homo sapiens

GOA TAX026768 GO:0051052 biological process regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 377 NA Homo sapiens

GOA FEX012376 The genes express in medium or high level in at least 95% samples in cervical cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1272 28818916 Homo sapiens

HPA-PathologyAtlas FEX012443 The normalized gene expressions no less than 30 in the tissue of pancreas. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1796 25613900 Homo sapiens

HPA-RNAcon TAX000469 Genes annotated by the GO term GO:0016310. The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. (more detail) 303 NA Homo sapiens

MSigDB TAX000177 Genes annotated by the GO term GO:0006259. The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. (more detail) 254 NA Homo sapiens

MSigDB FEX012441 The normalized gene expressions no less than 30 in the tissue of lymph node. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1512 25613900 Homo sapiens

HPA-RNAcon MOX004648 Genes associated with Computational Drug Signature SELENIUM Genes associated with Computational Drug Signature SELENIUM, curated by the Drug Signature Database (more detail) 1491 25990557 Homo sapiens

DSigDB FEX012454 The normalized gene expressions no less than 30 in the tissue of tonsil. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1457 25613900 Homo sapiens

HPA-RNAcon FEX012520 The normalized gene expressions no less than 30 in the tissue of ovary from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1107 25613900 Homo sapiens

HPA-normRNA TAX021603 GO:0032501 biological process multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its functio (more detail) 3323 NA Homo sapiens

GOA IEI007823 Protein protein interactors of human gene MDM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MDM2 (SwissProt ID=Q (more detail) 765 17535438 Homo sapiens

I2D TAX030185 GO:0080135 biological process regulation of cellular response to stress Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular (more detail) 618 NA Homo sapiens

GOA FEX012393 The genes express in medium or high level in at least 95% samples in urothelial cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1370 28818916 Homo sapiens

HPA-PathologyAtlas MEX003284 Genes associated with Perturbagen Signature glibenclamide Genes associated with Perturbagen Signature glibenclamide, curated by the Drug Signature Database (D (more detail) 1269 25990557 Homo sapiens

DSigDB MOX000607 Genes associated with Computational Drug Signature trichostatin A Genes associated with Computational Drug Signature trichostatin A, curated by the Drug Signature Dat (more detail) 3377 25990557 Homo sapiens

DSigDB MAX000661 Genes down regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. Polymorphisms in nitrosamine metabolism, DNA repair, and immune response genes have been associated (more detail) 1219 NA Homo sapiens

MSigDB FEX012382 The genes express in medium or high level in at least 95% samples in skin cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1134 28818916 Homo sapiens

HPA-PathologyAtlas TAX025737 GO:0046777 biological process protein autophosphorylation The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylat (more detail) 198 NA Homo sapiens

GOA MEX001224 Genes associated with Kinase Inhibitor NVP TAE684 Genes associated with Kinase Inhibitor NVP-TAE684, curated by the Drug Signature Database (DSigDB). (more detail) 203 25990557 Homo sapiens

DSigDB TAX001337 Genes annotated by the GO term GO:0004674. Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate. (more detail) 202 NA Homo sapiens

MSigDB IEI003945 Protein protein interactors of human gene EED from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EED (SwissProt ID=O7 (more detail) 465 17535438 Homo sapiens

I2D FEX012592 The normalized gene expressions no less than 30 in the tissue of cerebellum from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1225 25613900 Homo sapiens

HPA-FANTOM5 MEX001791 Genes associated with Kinase Inhibitor NVP TAE684 Genes associated with Kinase Inhibitor NVP-TAE684, curated by the Drug Signature Database (DSigDB). (more detail) 210 25990557 Homo sapiens

DSigDB TAX013490 GO:0000785 cellular component chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. (more detail) 345 NA Homo sapiens

GOA TAX013940 GO:0001932 biological process regulation of protein phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into an ami (more detail) 1366 NA Homo sapiens

GOA FEX010165 hsa miR 92a 3p HITS-CLIP, Functional MTI (Weak) (more detail) 1256 NA Homo sapiens

mirTARbase MEX001653 Genes associated with Kinase Inhibitor staurosporine Genes associated with Kinase Inhibitor staurosporine, curated by the Drug Signature Database (DSigDB (more detail) 195 25990557 Homo sapiens

DSigDB TAX016441 GO:0006575 biological process cellular modified amino acid metabolic process The chemical reactions and pathways involving compounds derived from amino acids, organic acids cont (more detail) 195 NA Homo sapiens

GOA TAX000540 Genes annotated by the GO term GO:0006468. The process of introducing a phosphate group on to a protein. (more detail) 270 NA Homo sapiens

MSigDB TAX027984 GO:0060548 biological process negative regulation of cell death Any process that decreases the rate or frequency of cell death. Cell death is the specific activatio (more detail) 935 NA Homo sapiens

GOA TAX016281 GO:0006364 biological process rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more (more detail) 194 NA Homo sapiens

GOA TAX019495 GO:0018209 biological process peptidyl serine modification The modification of peptidyl-serine. (more detail) 194 NA Homo sapiens

GOA MEX000995 Genes associated with Approved Drug bosutinib Genes associated with Approved Drug bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 199 25990557 Homo sapiens

DSigDB TAX026233 GO:0048585 biological process negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimul (more detail) 1456 NA Homo sapiens

GOA TAX017740 GO:0009653 biological process anatomical structure morphogenesis The process in which anatomical structures are generated and organized. Morphogenesis pertains to th (more detail) 1319 NA Homo sapiens

GOA TAX019498 GO:0018212 biological process peptidyl tyrosine modification The modification of peptidyl-tyrosine. (more detail) 193 NA Homo sapiens

GOA TAX016313 GO:0006412 biological process translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or (more detail) 193 NA Homo sapiens

GOA IEI014578 Protein protein interactors of human gene UBE2I from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2I (SwissProt ID= (more detail) 443 17535438 Homo sapiens

I2D FEX012572 The normalized gene expressions no less than 30 in the tissue of cerebral cortex from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 2294 25613900 Homo sapiens

HPA-FANTOM5 FEX000906 Colon Grade07 1950genes SuppTable2. Genes with differential expression (P (more detail) 1460 17210682 Homo sapiens

GeneSigDB TAX030033 GO:0072522 biological process purine containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. (more detail) 192 NA Homo sapiens

GOA TAX013553 GO:0000956 biological process nuclear transcribed mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukar (more detail) 191 NA Homo sapiens

GOA IEI011423 Protein protein interactors of human gene RNF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF2 (SwissProt ID=Q (more detail) 705 17535438 Homo sapiens

I2D FEX003056 StemCell Matushansky08 1453genes Supplemental Table 7 (pathways represented by genes overexpressed in dedifferentiated liposarcomas v (more detail) 1176 18310505 Homo sapiens

GeneSigDB TAX031705 GO:0140097 molecular function catalytic activity, acting on DNA Catalytic activity that acts to modify DNA. (more detail) 195 NA Homo sapiens

GOA TAX019463 GO:0018108 biological process peptidyl tyrosine phosphorylation The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine. (more detail) 190 NA Homo sapiens

GOA MOX003893 Genes associated with Computational Drug Signature COUMESTROL Genes associated with Computational Drug Signature COUMESTROL, curated by the Drug Signature Databas (more detail) 1709 25990557 Homo sapiens

DSigDB TAX032238 GO:1901700 biological process response to oxygen containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 1276 NA Homo sapiens

GOA TAX026814 GO:0051128 biological process regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arr (more detail) 2353 NA Homo sapiens

GOA MEX001635 Genes associated with Kinase Inhibitor BX 912 Genes associated with Kinase Inhibitor BX-912, curated by the Drug Signature Database (DSigDB). (more detail) 203 25990557 Homo sapiens

DSigDB TAX026891 GO:0051240 biological process positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of an organismal process, any (more detail) 1604 NA Homo sapiens

GOA TAX020340 GO:0030162 biological process regulation of proteolysis Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bond (more detail) 790 NA Homo sapiens

GOA TAX016251 GO:0006310 biological process DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combination (more detail) 189 NA Homo sapiens

GOA MEX001777 Genes associated with Kinase Inhibitor HG 14 10 04 Genes associated with Kinase Inhibitor HG-14-10-04, curated by the Drug Signature Database (DSigDB). (more detail) 202 25990557 Homo sapiens

DSigDB TAX025550 GO:0046390 biological process ribose phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylat (more detail) 193 NA Homo sapiens

GOA TAX017637 GO:0009260 biological process ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consi (more detail) 188 NA Homo sapiens

GOA MAX001392 Genes up regulated in TC71 and EWS502 cells (Ewing's sarcoma) by EWSR1 FLI1 [GeneID=2130;2314] as inferred from RNAi knockdown of this fusion protein. A number of solid tumors, such as alveolar rhabdomyosarcoma, synovial sarcoma, and myxoid liposarcom (more detail) 1149 NA Homo sapiens

MSigDB FEX012500 The normalized gene expressions no less than 30 in the tissue of tonsil from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1003 25613900 Homo sapiens

HPA-normRNA MAX001341 Genes involved in DNA repair, compiled manually by the authors. We have identified a gene-profile signature for human primary malignant melanoma associated with met (more detail) 223 NA Homo sapiens

MSigDB MEX002970 Genes associated with Perturbagen Signature danazol Genes associated with Perturbagen Signature danazol, curated by the Drug Signature Database (DSigDB) (more detail) 1173 25990557 Homo sapiens

DSigDB MEX001522 Genes associated with Kinase Inhibitor 841290 80 0 Genes associated with Kinase Inhibitor 841290-80-0, curated by the Drug Signature Database (DSigDB). (more detail) 201 25990557 Homo sapiens

DSigDB TAX015343 GO:0004721 molecular function phosphoprotein phosphatase activity Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kin (more detail) 187 NA Homo sapiens

GOA TAX017142 GO:0008234 molecular function cysteine type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulf (more detail) 200 NA Homo sapiens

GOA IEI012710 Protein protein interactors of human gene SNW1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNW1 (SwissProt ID=Q (more detail) 636 17535438 Homo sapiens

I2D TAX017145 GO:0008237 molecular function metallopeptidase activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, on (more detail) 185 NA Homo sapiens

GOA TAX016270 GO:0006352 biological process DNA templated transcription, initiation Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core p (more detail) 185 NA Homo sapiens

GOA FEX012427 The normalized gene expressions no less than 30 in the tissue of breast. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1609 25613900 Homo sapiens

HPA-RNAcon TAX019126 GO:0016607 cellular component nuclear speck A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to (more detail) 378 NA Homo sapiens

GOA TAX013650 GO:0001227 molecular function DNA binding transcription repressor activity, RNA polymerase II specific A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA (more detail) 228 NA Homo sapiens

GOA MEX002024 Genes associated with Kinase Inhibitor 841290 80 0 Genes associated with Kinase Inhibitor 841290-80-0, curated by the Drug Signature Database (DSigDB). (more detail) 192 25990557 Homo sapiens

DSigDB WIG000698 Genes involved in Antigen processing: Ubiquitination & Proteasome degradation (more detail) 199 NA Homo sapiens

MSigDB TAX017821 GO:0009967 biological process positive regulation of signal transduction Any process that activates or increases the frequency, rate or extent of signal transduction. (more detail) 1503 NA Homo sapiens

GOA IEI000775 Protein protein interactors of human gene AR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AR (SwissProt ID=P10 (more detail) 347 17535438 Homo sapiens

I2D TAX024142 GO:0043069 biological process negative regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, (more detail) 861 NA Homo sapiens

GOA FEX012381 The genes express in medium or high level in at least 95% samples in prostate cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 2113 28818916 Homo sapiens

HPA-PathologyAtlas TAX025274 GO:0045786 biological process negative regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle (more detail) 508 NA Homo sapiens

GOA FEX009821 hsa miR 16 5p HITS-CLIP, Functional MTI (Weak) (more detail) 1440 NA Homo sapiens

mirTARbase MEX002397 Genes associated with Kinase Inhibitor Sunitinib Genes associated with Kinase Inhibitor Sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 185 25990557 Homo sapiens

DSigDB TAX029987 GO:0072376 biological process protein activation cascade A response to a stimulus that consists of a sequential series of modifications to a set of proteins (more detail) 180 NA Homo sapiens

GOA TAX020929 GO:0031329 biological process regulation of cellular catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 744 NA Homo sapiens

GOA FEX012391 The genes express in medium or high level in at least 95% samples in glioma. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1119 28818916 Homo sapiens

HPA-PathologyAtlas TAX020242 GO:0023056 biological process positive regulation of signaling Any process that activates, maintains or increases the frequency, rate or extent of a signaling proc (more detail) 1644 NA Homo sapiens

GOA TAX016161 GO:0006164 biological process purine nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound co (more detail) 179 NA Homo sapiens

GOA TAX018028 GO:0010647 biological process positive regulation of cell communication Any process that increases the frequency, rate or extent of cell communication. Cell communication i (more detail) 1637 NA Homo sapiens

GOA MEX002276 Genes associated with Kinase Inhibitor Sunitinib Genes associated with Kinase Inhibitor Sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 183 25990557 Homo sapiens

DSigDB TAX030717 GO:0097164 biological process ammonium ion metabolic process The chemical reactions and pathways involving the ammonium ion. (more detail) 178 NA Homo sapiens

GOA TAX020180 GO:0022414 biological process reproductive process A biological process that directly contributes to the process of producing new individuals by one or (more detail) 1333 NA Homo sapiens

GOA TAX016906 GO:0007346 biological process regulation of mitotic cell cycle Any process that modulates the rate or extent of progress through the mitotic cell cycle. (more detail) 605 NA Homo sapiens

GOA TAX026791 GO:0051094 biological process positive regulation of developmental process Any process that activates or increases the rate or extent of development, the biological process wh (more detail) 1279 NA Homo sapiens

GOA TAX032546 GO:1902531 biological process regulation of intracellular signal transduction Any process that modulates the frequency, rate or extent of intracellular signal transduction. (more detail) 1788 NA Homo sapiens

GOA IEI011167 Protein protein interactors of human gene RELA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RELA (SwissProt ID=Q (more detail) 393 17535438 Homo sapiens

I2D TAX021951 GO:0033044 biological process regulation of chromosome organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arr (more detail) 309 NA Homo sapiens

GOA TAX017521 GO:0009123 biological process nucleoside monophosphate metabolic process The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a (more detail) 177 NA Homo sapiens

GOA MEX002854 Genes associated with Perturbagen Signature chlorzoxazone Genes associated with Perturbagen Signature chlorzoxazone, curated by the Drug Signature Database (D (more detail) 1224 25990557 Homo sapiens

DSigDB TAX024139 GO:0043066 biological process negative regulation of apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptoti (more detail) 845 NA Homo sapiens

GOA TAX026593 GO:0050790 biological process regulation of catalytic activity Any process that modulates the activity of an enzyme. (more detail) 2233 NA Homo sapiens

GOA MOX004855 Genes associated with Computational Drug Signature ZINC Genes associated with Computational Drug Signature ZINC, curated by the Drug Signature Database (DSi (more detail) 1573 25990557 Homo sapiens

DSigDB TAX024595 GO:0044093 biological process positive regulation of molecular function Any process that activates or increases the rate or extent of a molecular function, an elemental bio (more detail) 1688 NA Homo sapiens

GOA FEX012444 The normalized gene expressions no less than 30 in the tissue of pituitary gland. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1275 25613900 Homo sapiens

HPA-RNAcon TAX026960 GO:0051347 biological process positive regulation of transferase activity Any process that activates or increases the frequency, rate or extent of transferase activity, the c (more detail) 617 NA Homo sapiens

GOA TAX016809 GO:0007165 biological process signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a (more detail) 4709 NA Homo sapiens

GOA TAX019460 GO:0018105 biological process peptidyl serine phosphorylation The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine. (more detail) 175 NA Homo sapiens

GOA TAX017550 GO:0009152 biological process purine ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compoun (more detail) 175 NA Homo sapiens

GOA FAX000365 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif TTGTTT which matches annotation for MLLT7: myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila); translocated to, 7 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTGTTT w (more detail) 1894 NA Homo sapiens

MSigDB FEX000559 Breast Kreike07 3712genes Basal mets Table S5 Results of the supervised analysis using SAM software of 71 triple-negative tumors comparin (more detail) 2302 17910759 Homo sapiens

GeneSigDB FEX012435 The normalized gene expressions no less than 30 in the tissue of cerebral cortex. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 2679 25613900 Homo sapiens

HPA-RNAcon TAX001418 Genes annotated by the GO term GO:0003712. The function that links a sequence specific transcription factor to the core RNA polymerase II complex but does not bind DNA itself. (more detail) 225 NA Homo sapiens

MSigDB TAX020170 GO:0022402 biological process cell cycle process The cellular process that ensures successive accurate and complete genome replication and chromosome (more detail) 892 NA Homo sapiens

GOA TAX017972 GO:0010564 biological process regulation of cell cycle process Any process that modulates a cellular process that is involved in the progression of biochemical and (more detail) 667 NA Homo sapiens

GOA IEI012241 Protein protein interactors of human gene SIRT7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIRT7 (SwissProt ID= (more detail) 659 17535438 Homo sapiens

I2D TAX017726 GO:0009628 biological process response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 999 NA Homo sapiens

GOA FAX000325 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif SCGGAAGY which matches annotation for ELK1: ELK1, member of ETS oncogene family Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif SCGGAAGY (more detail) 1089 NA Homo sapiens

MSigDB TAX024438 GO:0043549 biological process regulation of kinase activity Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the tr (more detail) 840 NA Homo sapiens

GOA MEX001215 Genes associated with Kinase Inhibitor KW 2449 Genes associated with Kinase Inhibitor KW-2449, curated by the Drug Signature Database (DSigDB). (more detail) 182 25990557 Homo sapiens

DSigDB FEX012383 The genes express in medium or high level in at least 95% samples in stomach cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1495 28818916 Homo sapiens

HPA-PathologyAtlas FEX003033 StemCell Nuytten08 2072genes Table S2 List of all genes with a significantly changed expression level after the knockdown of EZH2 (more detail) 1664 17724462 Homo sapiens

GeneSigDB TAX000995 Genes annotated by the GO term GO:0005654. That part of the nuclear content other than the chromosomes or the nucleolus. (more detail) 269 NA Homo sapiens

MSigDB TAX024739 GO:0044421 cellular component extracellular region part Any constituent part of the extracellular region, the space external to the outermost structure of a (more detail) 3267 NA Homo sapiens

GOA FEX012439 The normalized gene expressions no less than 30 in the tissue of heart muscle. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 2033 25613900 Homo sapiens

HPA-RNAcon TAX016494 GO:0006643 biological process membrane lipid metabolic process The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with (more detail) 190 NA Homo sapiens

GOA IEI011482 Protein protein interactors of human gene RPA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPA1 (SwissProt ID=P (more detail) 466 17535438 Homo sapiens

I2D FEX012432 The normalized gene expressions no less than 30 in the tissue of adrenal gland. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1455 25613900 Homo sapiens

HPA-RNAcon IEI009227 Protein protein interactors of human gene OBSL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OBSL1 (SwissProt ID= (more detail) 584 17535438 Homo sapiens

I2D IEI010468 Protein protein interactors of human gene PRKAA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRKAA1 (SwissProt ID (more detail) 496 17535438 Homo sapiens

I2D FEX012380 The genes express in medium or high level in at least 95% samples in pancreatic cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1556 28818916 Homo sapiens

HPA-PathologyAtlas MEX002852 Genes associated with Perturbagen Signature chlortetracycline Genes associated with Perturbagen Signature chlortetracycline, curated by the Drug Signature Databas (more detail) 1083 25990557 Homo sapiens

DSigDB MEX003511 Genes associated with Perturbagen Signature lycorine Genes associated with Perturbagen Signature lycorine, curated by the Drug Signature Database (DSigDB (more detail) 1075 25990557 Homo sapiens

DSigDB TAX000573 Genes annotated by the GO term GO:0006508. The hydrolysis of a peptide bond or bonds within a protein. (more detail) 184 NA Homo sapiens

MSigDB TAX027145 GO:0051704 biological process multi organism process A biological process which involves another organism of the same or different species. (more detail) 1356 NA Homo sapiens

GOA TAX024432 GO:0043543 biological process protein acylation The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to (more detail) 166 NA Homo sapiens

GOA TAX024656 GO:0044272 biological process sulfur compound biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, suc (more detail) 175 NA Homo sapiens

GOA FEX002501 Ovarian Li09 2322genes cisplatinresistance Supplementary Table 3- Differentially expressed genes in isogenic cisplatin-resistant (Round5) vs. c (more detail) 1691 19505326 Homo sapiens

GeneSigDB PEX001788 Pkinase: Protein kinase domain (more detail) 165 NA Homo sapiens

Pfam TAX000868 Genes annotated by the GO term GO:0005737. All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. (more detail) 2023 NA Homo sapiens

MSigDB FEX000640 Breast Creighton08 2154genes Supplementary Data File 1 (more detail) 1610 18757322 Homo sapiens

GeneSigDB TAX001296 Genes annotated by the GO term GO:0008233. Catalysis of the hydrolysis of peptide bonds. (more detail) 169 NA Homo sapiens

MSigDB TAX017539 GO:0009141 biological process nucleoside triphosphate metabolic process The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a (more detail) 164 NA Homo sapiens

GOA FEX012452 The normalized gene expressions no less than 30 in the tissue of thyroid gland. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1564 25613900 Homo sapiens

HPA-RNAcon TAX020946 GO:0031347 biological process regulation of defense response Any process that modulates the frequency, rate or extent of a defense response. (more detail) 737 NA Homo sapiens

GOA MOX003885 Genes associated with Computational Drug Signature COPPER Genes associated with Computational Drug Signature COPPER, curated by the Drug Signature Database (D (more detail) 1609 25990557 Homo sapiens

DSigDB TAX014773 GO:0003714 molecular function transcription corepressor activity AA protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound (more detail) 222 NA Homo sapiens

GOA TAX000940 Genes annotated by the GO term GO:0032991. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. (more detail) 918 NA Homo sapiens

MSigDB FEX012496 The normalized gene expressions no less than 30 in the tissue of lymph node from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 862 25613900 Homo sapiens

HPA-normRNA TAX025312 GO:0045859 biological process regulation of protein kinase activity Any process that modulates the frequency, rate or extent of protein kinase activity. (more detail) 778 NA Homo sapiens

GOA FEX012504 The normalized gene expressions no less than 30 in the tissue of parathyroid gland from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1353 25613900 Homo sapiens

HPA-normRNA FEX012461 The normalized gene expressions no less than 30 in the tissue of parathyroid gland. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1353 25613900 Homo sapiens

HPA-RNAcon FAX000238 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif CACGTG which matches annotation for MYC: v myc myelocytomatosis viral oncogene homolog (avian) Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif CACGTG w (more detail) 945 NA Homo sapiens

MSigDB TAX026895 GO:0051248 biological process negative regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and (more detail) 1070 NA Homo sapiens

GOA FEX012591 The normalized gene expressions no less than 30 in the tissue of pancreas from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1490 25613900 Homo sapiens

HPA-FANTOM5 FEX002243 Lymphoma Tome05 1333genes SuppTable 4. Proliferation signature file (more detail) 627 16081686 Homo sapiens

GeneSigDB FEX002505 Breast Nagaraja10 3054genes Supplementary Table: down in clear cell (1709) (more detail) 2170 20081105 Homo sapiens

GeneSigDB TAX017748 GO:0009719 biological process response to endogenous stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 981 NA Homo sapiens

GOA IEI009617 Protein protein interactors of human gene PCNA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCNA (SwissProt ID=P (more detail) 298 17535438 Homo sapiens

I2D GOX001377 Genes regulated by the microRNA hsa miR 181c 5p using target scan (more detail) 1304 NA Homo sapiens

TargetScan GOX001462 Genes regulated by the microRNA hsa miR 4262 using target scan (more detail) 1304 NA Homo sapiens

TargetScan GOX001425 Genes regulated by the microRNA hsa miR 181b 5p using target scan (more detail) 1304 NA Homo sapiens

TargetScan GOX001490 Genes regulated by the microRNA hsa miR 181a 5p using target scan (more detail) 1304 NA Homo sapiens

TargetScan GOX001362 Genes regulated by the microRNA hsa miR 181d 5p using target scan (more detail) 1304 NA Homo sapiens

TargetScan FEX012377 The genes express in medium or high level in at least 95% samples in endometrial cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1523 28818916 Homo sapiens

HPA-PathologyAtlas FEX000652 Breast Liu08 1878genes Supplemental Table 1. Pathways and associated genes analyzed in the study. (more detail) 1093 18786252 Homo sapiens

GeneSigDB IEI010217 Protein protein interactors of human gene POLR2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2A (SwissProt ID (more detail) 257 17535438 Homo sapiens

I2D TAX016078 GO:0006022 biological process aminoglycan metabolic process The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that (more detail) 160 NA Homo sapiens

GOA FOX000528 Genes in the cancer module 198 (more detail) 294 NA Homo sapiens

MSigDB FEX012509 The normalized gene expressions no less than 30 in the tissue of dendritic cells from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1427 25613900 Homo sapiens

HPA-normRNA FEX012474 The normalized gene expressions no less than 30 in the tissue of dendritic cells. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1427 25613900 Homo sapiens

HPA-RNAcon MEX003113 Genes associated with Perturbagen Signature emetine Genes associated with Perturbagen Signature emetine, curated by the Drug Signature Database (DSigDB) (more detail) 1395 25990557 Homo sapiens

DSigDB FEX012445 The normalized gene expressions no less than 30 in the tissue of placenta. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1833 25613900 Homo sapiens

HPA-RNAcon FEX012484 The normalized gene expressions no less than 30 in the tissue of vagina. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1283 25613900 Homo sapiens

HPA-RNAcon MOX001175 Genes associated with Computational Drug Signature POTASSIUM CHROMATE Genes associated with Computational Drug Signature POTASSIUM CHROMATE, curated by the Drug Signature (more detail) 1795 25990557 Homo sapiens

DSigDB TAX001362 Genes annotated by the GO term GO:0003702. Functions to initiate or regulate RNA polymerase II transcription. (more detail) 180 NA Homo sapiens

MSigDB TAX016302 GO:0006399 biological process tRNA metabolic process The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA mo (more detail) 159 NA Homo sapiens

GOA TAX014364 GO:0002684 biological process positive regulation of immune system process Any process that activates or increases the frequency, rate, or extent of an immune system process. (more detail) 991 NA Homo sapiens

GOA FEX012438 The normalized gene expressions no less than 30 in the tissue of esophagus. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1675 25613900 Homo sapiens

HPA-RNAcon FEX012480 The normalized gene expressions no less than 30 in the tissue of endometrium. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1201 25613900 Homo sapiens

HPA-RNAcon FEX012578 The normalized gene expressions no less than 30 in the tissue of ovary from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 978 25613900 Homo sapiens

HPA-FANTOM5 IEI002249 Protein protein interactors of human gene CDK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK2 (SwissProt ID=P (more detail) 595 17535438 Homo sapiens

I2D TAX017558 GO:0009161 biological process ribonucleoside monophosphate metabolic process The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting (more detail) 158 NA Homo sapiens

GOA MOX003144 Genes associated with Computational Drug Signature Bortezomib Genes associated with Computational Drug Signature Bortezomib, curated by the Drug Signature Databas (more detail) 850 25990557 Homo sapiens

DSigDB IEI015181 Protein protein interactors of human gene YWHAZ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YWHAZ (SwissProt ID= (more detail) 748 17535438 Homo sapiens

I2D FEX012602 The normalized gene expressions no less than 30 in the tissue of vagina from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1023 25613900 Homo sapiens

HPA-FANTOM5 TAX016283 GO:0006367 biological process transcription initiation from RNA polymerase II promoter Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA (more detail) 157 NA Homo sapiens

GOA IEI000760 Protein protein interactors of human gene APP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APP (SwissProt ID=P0 (more detail) 2008 17535438 Homo sapiens

I2D FEX012579 The normalized gene expressions no less than 30 in the tissue of pituitary gland from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1048 25613900 Homo sapiens

HPA-FANTOM5 FEX012532 The normalized gene expressions no less than 30 in the tissue of adrenal gland from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 1239 25613900 Homo sapiens

HPA-GTEx TAX017174 GO:0008284 biological process positive regulation of cell proliferation Any process that activates or increases the rate or extent of cell proliferation. (more detail) 871 NA Homo sapiens

GOA TAX016810 GO:0007166 biological process cell surface receptor signaling pathway A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pa (more detail) 2199 NA Homo sapiens

GOA TAX000372 Genes annotated by the GO term GO:0048519. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. (more detail) 658 NA Homo sapiens

MSigDB IEI003162 Protein protein interactors of human gene CUL5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUL5 (SwissProt ID=Q (more detail) 386 17535438 Homo sapiens

I2D FEX012446 The normalized gene expressions no less than 30 in the tissue of seminal vesicle. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1437 25613900 Homo sapiens

HPA-RNAcon TAX026860 GO:0051188 biological process cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is re (more detail) 222 NA Homo sapiens

GOA TAX016700 GO:0006956 biological process complement activation Any process involved in the activation of any of the steps of the complement cascade, which allows f (more detail) 155 NA Homo sapiens

GOA FEX012433 The normalized gene expressions no less than 30 in the tissue of basal ganglia. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1903 25613900 Homo sapiens

HPA-RNAcon FEX012455 The normalized gene expressions no less than 30 in the tissue of urinary bladder. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1286 25613900 Homo sapiens

HPA-RNAcon TAX017716 GO:0009605 biological process response to external stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 1451 NA Homo sapiens

GOA FAX000225 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif AACTTT. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif AACTTT. Moti (more detail) 1744 NA Homo sapiens

MSigDB TAX024646 GO:0044255 biological process cellular lipid metabolic process The chemical reactions and pathways involving lipids, as carried out by individual cells. (more detail) 938 NA Homo sapiens

GOA TAX000996 Genes annotated by the GO term GO:0044451. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus. (more detail) 204 NA Homo sapiens

MSigDB TAX016243 GO:0006302 biological process double strand break repair The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a co (more detail) 154 NA Homo sapiens

GOA TAX030549 GO:0090501 biological process RNA phosphodiester bond hydrolysis The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by h (more detail) 154 NA Homo sapiens

GOA GOX001614 Genes regulated by the microRNA hsa miR 27a 3p using target scan (more detail) 1321 NA Homo sapiens

TargetScan GOX001431 Genes regulated by the microRNA hsa miR 27b 3p using target scan (more detail) 1321 NA Homo sapiens

TargetScan MEX002826 Genes associated with Perturbagen Signature cephaeline Genes associated with Perturbagen Signature cephaeline, curated by the Drug Signature Database (DSig (more detail) 1297 25990557 Homo sapiens

DSigDB TAX026892 GO:0051241 biological process negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, (more detail) 1105 NA Homo sapiens

GOA FEX012581 The normalized gene expressions no less than 30 in the tissue of seminal vesicle from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1122 25613900 Homo sapiens

HPA-FANTOM5 FEX012580 The normalized gene expressions no less than 30 in the tissue of placenta from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1640 25613900 Homo sapiens

HPA-FANTOM5 TAX000477 Genes annotated by the GO term GO:0048518. Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. (more detail) 700 NA Homo sapiens

MSigDB TAX032236 GO:1901698 biological process response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 827 NA Homo sapiens

GOA TAX021009 GO:0031461 cellular component cullin RING ubiquitin ligase complex Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family a (more detail) 176 NA Homo sapiens

GOA TAX032020 GO:1901136 biological process carbohydrate derivative catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative. (more detail) 176 NA Homo sapiens

GOA FEX012430 The normalized gene expressions no less than 30 in the tissue of salivary gland. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1566 25613900 Homo sapiens

HPA-RNAcon TAX017822 GO:0009968 biological process negative regulation of signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. (more detail) 1136 NA Homo sapiens

GOA MAX000556 Genes down regulated in fibroblasts expressing mutant forms of ERCC3 [GeneID=2071] after UV irradiation. Xeroderma pigmentosum (XP) and trichothiodystrophy (TTD) syndromes are characterized by deficiency i (more detail) 811 NA Homo sapiens

MSigDB IEI004834 Protein protein interactors of human gene FN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FN1 (SwissProt ID=P0 (more detail) 760 17535438 Homo sapiens

I2D FEX012440 The normalized gene expressions no less than 30 in the tissue of kidney. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1774 25613900 Homo sapiens

HPA-RNAcon TAX020371 GO:0030203 biological process glycosaminoglycan metabolic process The chemical reactions and pathways involving glycosaminoglycans, any one of a group of polysacchari (more detail) 151 NA Homo sapiens

GOA IEI011483 Protein protein interactors of human gene RPA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPA2 (SwissProt ID=P (more detail) 428 17535438 Homo sapiens

I2D MOX005113 Genes associated with Computational Drug Signature TERT BUTYL HYDROPEROXIDE Genes associated with Computational Drug Signature TERT-BUTYL HYDROPEROXIDE, curated by the Drug Sig (more detail) 1290 25990557 Homo sapiens

DSigDB TAX026583 GO:0050776 biological process regulation of immune response Any process that modulates the frequency, rate or extent of the immune response, the immunological r (more detail) 994 NA Homo sapiens

GOA IEI005928 Protein protein interactors of human gene HNRNPA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPA1 (SwissProt I (more detail) 349 17535438 Homo sapiens

I2D TAX015338 GO:0004713 molecular function protein tyrosine kinase activity Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. (more detail) 181 NA Homo sapiens

GOA FEX002298 Lymphoma Lam08 1502genes Table S5. Fig4a ABC STAT3diffgenes (more detail) 863 18160665 Homo sapiens

GeneSigDB FEX012566 The normalized gene expressions no less than 30 in the tissue of breast from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1295 25613900 Homo sapiens

HPA-FANTOM5 TAX026585 GO:0050778 biological process positive regulation of immune response Any process that activates or increases the frequency, rate or extent of the immune response, the im (more detail) 699 NA Homo sapiens

GOA FAX000265 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif CTTTGT which matches annotation for LEF1: lymphoid enhancer binding factor 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif CTTTGT w (more detail) 1810 NA Homo sapiens

MSigDB MOX004109 Genes associated with Computational Drug Signature 5 Fluorouracil Genes associated with Computational Drug Signature 5-Fluorouracil, curated by the Drug Signature Dat (more detail) 1167 25990557 Homo sapiens

DSigDB FEX012060 hsa miR 26b 5p HITS-CLIP, Functional MTI (Weak) (more detail) 1740 NA Homo sapiens

mirTARbase MEX002417 Genes associated with Kinase Inhibitor Nintedanib Genes associated with Kinase Inhibitor Nintedanib, curated by the Drug Signature Database (DSigDB). (more detail) 158 25990557 Homo sapiens

DSigDB MEX002280 Genes associated with Kinase Inhibitor Vargatef Genes associated with Kinase Inhibitor Vargatef, curated by the Drug Signature Database (DSigDB). (more detail) 158 25990557 Homo sapiens

DSigDB TAX015869 GO:0005681 cellular component spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleopro (more detail) 189 NA Homo sapiens

GOA WIG000975 Genes involved in Metabolism of amino acids and derivatives (more detail) 192 NA Homo sapiens

MSigDB TAX017881 GO:0010243 biological process response to organonitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 767 NA Homo sapiens

GOA MOX004024 Genes associated with Computational Drug Signature doxorubicin Genes associated with Computational Drug Signature doxorubicin, curated by the Drug Signature Databa (more detail) 736 25990557 Homo sapiens

DSigDB IEI003163 Protein protein interactors of human gene CUL7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUL7 (SwissProt ID=Q (more detail) 619 17535438 Homo sapiens

I2D TAX000482 Genes annotated by the GO term GO:0048522. Any process that activates or increases the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. (more detail) 660 NA Homo sapiens

MSigDB TAX014137 GO:0002253 biological process activation of immune response Any process that initiates an immune response. (more detail) 509 NA Homo sapiens

GOA IEI009196 Protein protein interactors of human gene NXF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NXF1 (SwissProt ID=Q (more detail) 1113 17535438 Homo sapiens

I2D TAX022473 GO:0034404 biological process nucleobase containing small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleobase-containing small mole (more detail) 148 NA Homo sapiens

GOA TAX016211 GO:0006260 biological process DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replicat (more detail) 148 NA Homo sapiens

GOA MOX004956 Genes associated with Computational Drug Signature AFLATOXIN B1 Genes associated with Computational Drug Signature AFLATOXIN B1, curated by the Drug Signature Datab (more detail) 2934 25990557 Homo sapiens

DSigDB FEX001143 Immune Kong10 1790genes ImmPort Anti IgMvsControl ImmPort genelist of B Cell Stimulation: Anti-IgM vs. Control (more detail) 1095 20460173 Homo sapiens

GeneSigDB TAX021422 GO:0032269 biological process negative regulation of cellular protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 1010 NA Homo sapiens

GOA FEX012533 The normalized gene expressions no less than 30 in the tissue of esophagus from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 1248 25613900 Homo sapiens

HPA-GTEx TAX000399 Genes annotated by the GO term GO:0045934. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. (more detail) 208 NA Homo sapiens

MSigDB MEX001293 Genes associated with Kinase Inhibitor AST 487 Genes associated with Kinase Inhibitor AST 487, curated by the Drug Signature Database (DSigDB). (more detail) 147 25990557 Homo sapiens

DSigDB TAX019047 GO:0016485 biological process protein processing Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. (more detail) 147 NA Homo sapiens

GOA TAX019188 GO:0016741 molecular function transferase activity, transferring one carbon groups Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor). (more detail) 224 NA Homo sapiens

GOA FEX012462 The normalized gene expressions no less than 30 in the tissue of testis. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 2092 25613900 Homo sapiens

HPA-RNAcon TAX019198 GO:0016757 molecular function transferase activity, transferring glycosyl groups Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). (more detail) 286 NA Homo sapiens

GOA TAX024239 GO:0043230 cellular component extracellular organelle Organized structure of distinctive morphology and function, occurring outside the cell. Includes, fo (more detail) 2042 NA Homo sapiens

GOA TAX032239 GO:1901701 biological process cellular response to oxygen containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 751 NA Homo sapiens

GOA IEI005837 Protein protein interactors of human gene HIF1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HIF1A (SwissProt ID= (more detail) 366 17535438 Homo sapiens

I2D TAX033013 GO:1903561 cellular component extracellular vesicle Any vesicle that is part of the extracellular region. (more detail) 2041 NA Homo sapiens

GOA TAX000378 Genes annotated by the GO term GO:0048523. Any process that stops, prevents or reduces the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. (more detail) 627 NA Homo sapiens

MSigDB TAX017542 GO:0009144 biological process purine nucleoside triphosphate metabolic process The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting (more detail) 146 NA Homo sapiens

GOA FAX000352 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif TGGAAA which matches annotation for NFAT
NFATC Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TGGAAA w (more detail) 1740 NA Homo sapiens

MSigDB FEX012571 The normalized gene expressions no less than 30 in the tissue of basal ganglia from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1686 25613900 Homo sapiens

HPA-FANTOM5 IEI003065 Protein protein interactors of human gene CSNK2A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSNK2A1 (SwissProt I (more detail) 448 17535438 Homo sapiens

I2D TAX028707 GO:0070062 cellular component extracellular exosome A vesicle that is released into the extracellular region by fusion of the limiting endosomal membran (more detail) 2021 NA Homo sapiens

GOA MEX001768 Genes associated with Kinase Inhibitor HG 9 91 01 Genes associated with Kinase Inhibitor HG-9-91-01, curated by the Drug Signature Database (DSigDB). (more detail) 150 25990557 Homo sapiens

DSigDB TAX000738 Genes annotated by the GO term GO:0006396. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. (more detail) 169 NA Homo sapiens

MSigDB TAX017524 GO:0009126 biological process purine nucleoside monophosphate metabolic process The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting (more detail) 145 NA Homo sapiens

GOA TAX017591 GO:0009199 biological process ribonucleoside triphosphate metabolic process The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting o (more detail) 145 NA Homo sapiens

GOA TAX000408 Genes annotated by the GO term GO:0016481. Any process that stops, prevents or reduces the frequency, rate or extent of transcription. (more detail) 185 NA Homo sapiens

MSigDB FEX012431 The normalized gene expressions no less than 30 in the tissue of adipose tissue. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1544 25613900 Homo sapiens

HPA-RNAcon MEX003455 Genes associated with Perturbagen Signature lanatoside C Genes associated with Perturbagen Signature lanatoside C, curated by the Drug Signature Database (DS (more detail) 759 25990557 Homo sapiens

DSigDB FEX010349 hsa let 7b 5p HITS-CLIP, Functional MTI (Weak) (more detail) 1129 NA Homo sapiens

mirTARbase TAX017970 GO:0010562 biological process positive regulation of phosphorus metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 1046 NA Homo sapiens

GOA TAX025359 GO:0045937 biological process positive regulation of phosphate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 1046 NA Homo sapiens

GOA MEX002517 Genes associated with Perturbagen Signature 8 azaguanine Genes associated with Perturbagen Signature 8-azaguanine, curated by the Drug Signature Database (DS (more detail) 980 25990557 Homo sapiens

DSigDB MEX002012 Genes associated with Kinase Inhibitor Foretinib Genes associated with Kinase Inhibitor Foretinib, curated by the Drug Signature Database (DSigDB). (more detail) 149 25990557 Homo sapiens

DSigDB TAX017564 GO:0009167 biological process purine ribonucleoside monophosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consis (more detail) 144 NA Homo sapiens

GOA TAX016511 GO:0006665 biological process sphingolipid metabolic process The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the (more detail) 144 NA Homo sapiens

GOA MAX000147 Set 'Myc targets2': targets of c Myc [GeneID=4609] and Max [GeneID=4149] identified by ChIP on chip in a Burkitt's lymphoma cell line; overlap set. Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear, howev (more detail) 714 NA Homo sapiens

MSigDB IEI009502 Protein protein interactors of human gene PARP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PARP1 (SwissProt ID= (more detail) 266 17535438 Homo sapiens

I2D FEX012449 The normalized gene expressions no less than 30 in the tissue of spleen. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1522 25613900 Homo sapiens

HPA-RNAcon TAX023779 GO:0042327 biological process positive regulation of phosphorylation Any process that activates or increases the frequency, rate or extent of addition of phosphate group (more detail) 977 NA Homo sapiens

GOA TAX000054 Genes annotated by the GO term GO:0009058. The energy requiring part of metabolism in which simpler substances are transformed into more complex ones, as in growth and other biosynthetic processes. (more detail) 453 NA Homo sapiens

MSigDB FEX012483 The normalized gene expressions no less than 30 in the tissue of smooth muscle. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1353 25613900 Homo sapiens

HPA-RNAcon MAX000149 Set 'Nanog targets': genes upregulated and identified by ChIP on chip as Nanog [GeneID=79923] transcription factor targets in human embryonic stem cells. Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear, howev (more detail) 892 NA Homo sapiens

MSigDB TAX013494 GO:0000790 cellular component nuclear chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in t (more detail) 209 NA Homo sapiens

GOA TAX024028 GO:0042803 molecular function protein homodimerization activity Interacting selectively and non-covalently with an identical protein to form a homodimer. (more detail) 803 NA Homo sapiens

GOA IEI002198 Protein protein interactors of human gene CDC5L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC5L (SwissProt ID= (more detail) 622 17535438 Homo sapiens

I2D MEX003031 Genes associated with Perturbagen Signature digoxin Genes associated with Perturbagen Signature digoxin, curated by the Drug Signature Database (DSigDB) (more detail) 661 25990557 Homo sapiens

DSigDB TAX032548 GO:1902533 biological process positive regulation of intracellular signal transduction Any process that activates or increases the frequency, rate or extent of intracellular signal transd (more detail) 993 NA Homo sapiens

GOA IEI003122 Protein protein interactors of human gene CTNNB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTNNB1 (SwissProt ID (more detail) 454 17535438 Homo sapiens

I2D TAX026916 GO:0051276 biological process chromosome organization A process that is carried out at the cellular level that results in the assembly, arrangement of con (more detail) 328 NA Homo sapiens

GOA FEX012392 The genes express in medium or high level in at least 95% samples in lymphoma. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 751 28818916 Homo sapiens

HPA-PathologyAtlas TAX017705 GO:0009451 biological process RNA modification The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule (more detail) 142 NA Homo sapiens

GOA FEX012544 The normalized gene expressions no less than 30 in the tissue of cerebellum from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 1341 25613900 Homo sapiens

HPA-GTEx MEX001115 Genes associated with Approved Drug crizotinib Genes associated with Approved Drug crizotinib, curated by the Drug Signature Database (DSigDB). (more detail) 146 25990557 Homo sapiens

DSigDB FEX012590 The normalized gene expressions no less than 30 in the tissue of lymph node from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1229 25613900 Homo sapiens

HPA-FANTOM5 TAX018843 GO:0016053 biological process organic acid biosynthetic process The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound (more detail) 313 NA Homo sapiens

GOA TAX016484 GO:0006629 biological process lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but no (more detail) 1183 NA Homo sapiens

GOA WIG000921 Genes involved in Immune System (more detail) 893 NA Homo sapiens

MSigDB IEI011048 Protein protein interactors of human gene RB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RB1 (SwissProt ID=P0 (more detail) 262 17535438 Homo sapiens

I2D TAX017409 GO:0008757 molecular function S adenosylmethionine dependent methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate. (more detail) 157 NA Homo sapiens

GOA TAX026790 GO:0051093 biological process negative regulation of developmental process Any process that stops, prevents or reduces the rate or extent of development, the biological proces (more detail) 880 NA Homo sapiens

GOA FEX008665 hsa miR 93 5p HITS-CLIP, Functional MTI (Weak) (more detail) 1119 NA Homo sapiens

mirTARbase MOX002182 Genes associated with Computational Drug Signature troglitazone Genes associated with Computational Drug Signature troglitazone, curated by the Drug Signature Datab (more detail) 627 25990557 Homo sapiens

DSigDB TAX016702 GO:0006958 biological process complement activation, classical pathway Any process involved in the activation of any of the steps of the classical pathway of the complemen (more detail) 140 NA Homo sapiens

GOA TAX025552 GO:0046394 biological process carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid (more detail) 312 NA Homo sapiens

GOA TAX018029 GO:0010648 biological process negative regulation of cell communication Any process that decreases the frequency, rate or extent of cell communication. Cell communication i (more detail) 1232 NA Homo sapiens

GOA GOX001521 Genes regulated by the microRNA hsa miR 124 3p.1 using target scan (more detail) 1722 NA Homo sapiens

TargetScan TAX020243 GO:0023057 biological process negative regulation of signaling Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. (more detail) 1236 NA Homo sapiens

GOA TAX000396 Genes annotated by the GO term GO:0009892. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. (more detail) 258 NA Homo sapiens

MSigDB TAX017597 GO:0009205 biological process purine ribonucleoside triphosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consist (more detail) 139 NA Homo sapiens

GOA FAX000270 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif GATTGGY. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif GATTGGY. Mot (more detail) 1050 NA Homo sapiens

MSigDB FEX012589 The normalized gene expressions no less than 30 in the tissue of urinary bladder from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1091 25613900 Homo sapiens

HPA-FANTOM5 TAX024855 GO:0044798 cellular component nuclear transcription factor complex A protein complex, located in the nucleus, that is capable of associating with DNA by direct binding (more detail) 169 NA Homo sapiens

GOA FEX012586 The normalized gene expressions no less than 30 in the tissue of thyroid gland from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1233 25613900 Homo sapiens

HPA-FANTOM5 TAX024539 GO:0043933 biological process protein containing complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the forma (more detail) 1686 NA Homo sapiens

GOA TAX015197 GO:0004519 molecular function endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. (more detail) 138 NA Homo sapiens

GOA WIG000763 Genes involved in Class I MHC mediated antigen processing & presentation (more detail) 237 NA Homo sapiens

MSigDB MEX001450 Genes associated with Kinase Inhibitor 602306 29 6 Genes associated with Kinase Inhibitor 602306-29-6, curated by the Drug Signature Database (DSigDB). (more detail) 154 25990557 Homo sapiens

DSigDB MOX000610 Genes associated with Computational Drug Signature curcumin Genes associated with Computational Drug Signature curcumin, curated by the Drug Signature Database (more detail) 517 25990557 Homo sapiens

DSigDB FEX008650 hsa miR 615 3p HITS-CLIP, Functional MTI (Weak) (more detail) 843 NA Homo sapiens

mirTARbase IEI006615 Protein protein interactors of human gene JUN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JUN (SwissProt ID=P0 (more detail) 375 17535438 Homo sapiens

I2D MEX001676 Genes associated with Kinase Inhibitor 627908 92 3 Genes associated with Kinase Inhibitor 627908-92-3, curated by the Drug Signature Database (DSigDB). (more detail) 146 25990557 Homo sapiens

DSigDB TAX022199 GO:0033674 biological process positive regulation of kinase activity Any process that activates or increases the frequency, rate or extent of kinase activity, the cataly (more detail) 545 NA Homo sapiens

GOA TAX017098 GO:0008168 molecular function methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule. (more detail) 213 NA Homo sapiens

GOA IEI004991 Protein protein interactors of human gene GABARAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GABARAP (SwissProt I (more detail) 622 17535438 Homo sapiens

I2D GOX001516 Genes regulated by the microRNA hsa miR 101 3p.2 using target scan (more detail) 1070 NA Homo sapiens

TargetScan TAX026787 GO:0051090 biological process regulation of DNA binding transcription factor activity Any process that modulates the frequency, rate or extent of the activity of a transcription factor, (more detail) 395 NA Homo sapiens

GOA MEX004394 Genes associated with Perturbagen Signature vorinostat Genes associated with Perturbagen Signature vorinostat, curated by the Drug Signature Database (DSig (more detail) 942 25990557 Homo sapiens

DSigDB TAX000377 Genes annotated by the GO term GO:0031324. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. (more detail) 255 NA Homo sapiens

MSigDB TAX013942 GO:0001934 biological process positive regulation of protein phosphorylation Any process that activates or increases the frequency, rate or extent of addition of phosphate group (more detail) 933 NA Homo sapiens

GOA FEX012378 The genes express in medium or high level in at least 95% samples in lung cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 964 28818916 Homo sapiens

HPA-PathologyAtlas MOX005023 Genes associated with Computational Drug Signature Disodium selenite Genes associated with Computational Drug Signature Disodium selenite, curated by the Drug Signature (more detail) 1304 25990557 Homo sapiens

DSigDB MEX001712 Genes associated with Kinase Inhibitor HG6 64 1 Genes associated with Kinase Inhibitor HG6-64-1, curated by the Drug Signature Database (DSigDB). (more detail) 145 25990557 Homo sapiens

DSigDB MEX003027 Genes associated with Perturbagen Signature digitoxigenin Genes associated with Perturbagen Signature digitoxigenin, curated by the Drug Signature Database (D (more detail) 857 25990557 Homo sapiens

DSigDB FEX012588 The normalized gene expressions no less than 30 in the tissue of tonsil from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1116 25613900 Homo sapiens

HPA-FANTOM5 IEI014566 Protein protein interactors of human gene UBE2D1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2D1 (SwissProt ID (more detail) 247 17535438 Homo sapiens

I2D IEI014169 Protein protein interactors of human gene TRAF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRAF6 (SwissProt ID= (more detail) 530 17535438 Homo sapiens

I2D IEI005946 Protein protein interactors of human gene HNRNPM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPM (SwissProt ID (more detail) 300 17535438 Homo sapiens

I2D MEX002396 Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 140 25990557 Homo sapiens

DSigDB TAX024662 GO:0044282 biological process small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular (more detail) 391 NA Homo sapiens

GOA MEX003028 Genes associated with Perturbagen Signature digitoxigenin Genes associated with Perturbagen Signature digitoxigenin, curated by the Drug Signature Database (D (more detail) 1263 25990557 Homo sapiens

DSigDB FEX000964 Futreal04 427genes ConsensusCancerGenes tumor suppressors : Tumor suppressors: both alleles of these genes need to be mutated for oncogenesi (more detail) 353 14993899 Homo sapiens

GeneSigDB TAX025156 GO:0045597 biological process positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of cell differentiation. (more detail) 907 NA Homo sapiens

GOA IEI005752 Protein protein interactors of human gene HDAC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDAC3 (SwissProt ID= (more detail) 276 17535438 Homo sapiens

I2D IEI008120 Protein protein interactors of human gene MOV10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MOV10 (SwissProt ID= (more detail) 978 17535438 Homo sapiens

I2D IEI012579 Protein protein interactors of human gene SMAD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMAD3 (SwissProt ID= (more detail) 390 17535438 Homo sapiens

I2D FAX000241 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif CAGGTG which matches annotation for TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif CAGGTG w (more detail) 2302 NA Homo sapiens

MSigDB FEX000689 Breast Parker09 1918genes IntrinsicGenes Compilation Supplementary Table 5. Compilation of Microarray Intrinsic Genes and PCR Genes (more detail) 1586 19204204 Homo sapiens

GeneSigDB FEX012437 The normalized gene expressions no less than 30 in the tissue of epididymis. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1520 25613900 Homo sapiens

HPA-RNAcon TAX018334 GO:0014070 biological process response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 724 NA Homo sapiens

GOA MEX002616 Genes associated with Perturbagen Signature anisomycin Genes associated with Perturbagen Signature anisomycin, curated by the Drug Signature Database (DSig (more detail) 1372 25990557 Homo sapiens

DSigDB FEX010573 hsa miR 17 5p HITS-CLIP, Functional MTI (Weak) (more detail) 1083 NA Homo sapiens

mirTARbase TAX001416 Genes annotated by the GO term GO:0016563. Any transcription regulator activity required for initiation or upregulation of transcription. (more detail) 172 NA Homo sapiens

MSigDB IEI003158 Protein protein interactors of human gene CUL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUL2 (SwissProt ID=Q (more detail) 414 17535438 Homo sapiens

I2D FEX000625 Breast Yau08 1518genes OxidativeStress Additional File 3. list of genes responsive to each of the eight different MCF7 treatment conditions (more detail) 1062 18631401 Homo sapiens

GeneSigDB MEX002774 Genes associated with Perturbagen Signature captopril Genes associated with Perturbagen Signature captopril, curated by the Drug Signature Database (DSigD (more detail) 945 25990557 Homo sapiens

DSigDB MOX000691 Genes associated with Computational Drug Signature Decitabine Genes associated with Computational Drug Signature Decitabine, curated by the Drug Signature Databas (more detail) 1740 25990557 Homo sapiens

DSigDB TAX018972 GO:0016311 biological process dephosphorylation The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. (more detail) 296 NA Homo sapiens

GOA TAX032213 GO:1901657 biological process glycosyl compound metabolic process The chemical reactions and pathways involving glycosyl compound. (more detail) 145 NA Homo sapiens

GOA GOX001618 Genes regulated by the microRNA hsa miR 302d 3p using target scan (more detail) 967 NA Homo sapiens

TargetScan GOX001598 Genes regulated by the microRNA hsa miR 302a 3p using target scan (more detail) 967 NA Homo sapiens

TargetScan GOX001712 Genes regulated by the microRNA hsa miR 372 3p using target scan (more detail) 967 NA Homo sapiens

TargetScan GOX001382 Genes regulated by the microRNA hsa miR 302b 3p using target scan (more detail) 967 NA Homo sapiens

TargetScan GOX001594 Genes regulated by the microRNA hsa miR 520e using target scan (more detail) 968 NA Homo sapiens

TargetScan FEX000186 Brain Lu06 1128genes Supplemental Table 1. List of known genes affected by radiation as detected by microarray analysis (more detail) 973 16424041 Homo sapiens

GeneSigDB FEX012476 The normalized gene expressions no less than 30 in the tissue of t cells. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1383 25613900 Homo sapiens

HPA-RNAcon FEX012512 The normalized gene expressions no less than 30 in the tissue of t cells from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1383 25613900 Homo sapiens

HPA-normRNA GOX001561 Genes regulated by the microRNA hsa miR 373 3p using target scan (more detail) 966 NA Homo sapiens

TargetScan GOX001549 Genes regulated by the microRNA hsa miR 302c 3p.1 using target scan (more detail) 966 NA Homo sapiens

TargetScan GOX001709 Genes regulated by the microRNA hsa miR 302e using target scan (more detail) 966 NA Homo sapiens

TargetScan GOX001742 Genes regulated by the microRNA hsa miR 520d 3p using target scan (more detail) 966 NA Homo sapiens

TargetScan MEX000921 Genes associated with Approved Drug dasatinib Genes associated with Approved Drug dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 144 25990557 Homo sapiens

DSigDB GOX001364 Genes regulated by the microRNA hsa miR 520b using target scan (more detail) 967 NA Homo sapiens

TargetScan GOX001539 Genes regulated by the microRNA hsa miR 520c 3p using target scan (more detail) 967 NA Homo sapiens

TargetScan GOX001738 Genes regulated by the microRNA hsa miR 520a 3p using target scan (more detail) 967 NA Homo sapiens

TargetScan FEX012576 The normalized gene expressions no less than 30 in the tissue of heart muscle from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1494 25613900 Homo sapiens

HPA-FANTOM5 TAX019811 GO:0019783 molecular function ubiquitin like protein specific protease activity Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin o (more detail) 131 NA Homo sapiens

GOA MAX000362 Genes up regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). Hepatoblastoma, the most common pediatric liver cancer, is tightly linked to excessive Wnt/beta-cate (more detail) 557 NA Homo sapiens

MSigDB IEI005948 Protein protein interactors of human gene HNRNPU from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPU (SwissProt ID (more detail) 369 17535438 Homo sapiens

I2D IEI010495 Protein protein interactors of human gene PRKDC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRKDC (SwissProt ID= (more detail) 309 17535438 Homo sapiens

I2D TAX017660 GO:0009314 biological process response to radiation Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 417 NA Homo sapiens

GOA FEX012502 The normalized gene expressions no less than 30 in the tissue of monocytes from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1425 25613900 Homo sapiens

HPA-normRNA FEX012458 The normalized gene expressions no less than 30 in the tissue of monocytes. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1425 25613900 Homo sapiens

HPA-RNAcon IEI001369 Protein protein interactors of human gene BMI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BMI1 (SwissProt ID=P (more detail) 368 17535438 Homo sapiens

I2D FEX012477 The normalized gene expressions no less than 30 in the tissue of appendix. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 996 25613900 Homo sapiens

HPA-RNAcon MEX003528 Genes associated with Perturbagen Signature meclofenoxate Genes associated with Perturbagen Signature meclofenoxate, curated by the Drug Signature Database (D (more detail) 681 25990557 Homo sapiens

DSigDB TAX001423 Genes annotated by the GO term GO:0016564. Any transcription regulator activity that prevents or downregulates transcription. (more detail) 150 NA Homo sapiens

MSigDB FEX012587 The normalized gene expressions no less than 30 in the tissue of tongue from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1336 25613900 Homo sapiens

HPA-FANTOM5 FEX012453 The normalized gene expressions no less than 30 in the tissue of tongue. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1336 25613900 Homo sapiens

HPA-RNAcon IEI005754 Protein protein interactors of human gene HDAC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDAC5 (SwissProt ID= (more detail) 340 17535438 Homo sapiens

I2D FEX012551 The normalized gene expressions no less than 30 in the tissue of adipose tissue from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 955 25613900 Homo sapiens

HPA-GTEx IEI010140 Protein protein interactors of human gene PML from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PML (SwissProt ID=P2 (more detail) 202 17535438 Homo sapiens

I2D TAX029737 GO:0071900 biological process regulation of protein serine/threonine kinase activity Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activit (more detail) 488 NA Homo sapiens

GOA MEX002010 Genes associated with Kinase Inhibitor MLS006011171 Genes associated with Kinase Inhibitor MLS006011171, curated by the Drug Signature Database (DSigDB) (more detail) 142 25990557 Homo sapiens

DSigDB MAX000336 Genes up regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress. Photodynamic therapy (PDT) is an anticancer approach utilizing a light-absorbing molecule and visibl (more detail) 764 NA Homo sapiens

MSigDB FEX012501 The normalized gene expressions no less than 30 in the tissue of granulocytes from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1926 25613900 Homo sapiens

HPA-normRNA FEX012456 The normalized gene expressions no less than 30 in the tissue of granulocytes. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1926 25613900 Homo sapiens

HPA-RNAcon TAX016355 GO:0006473 biological process protein acetylation The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from ace (more detail) 129 NA Homo sapiens

GOA TAX017800 GO:0009896 biological process positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 391 NA Homo sapiens

GOA IEI014853 Protein protein interactors of human gene VCAM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VCAM1 (SwissProt ID= (more detail) 641 17535438 Homo sapiens

I2D TAX014136 GO:0002252 biological process immune effector process Any process of the immune system that can potentially contribute to an immune response. (more detail) 1002 NA Homo sapiens

GOA WIG001288 Genes involved in Transcription (more detail) 137 NA Homo sapiens

MSigDB MEX002403 Genes associated with Kinase Inhibitor Crizotinib Genes associated with Kinase Inhibitor Crizotinib, curated by the Drug Signature Database (DSigDB). (more detail) 137 25990557 Homo sapiens

DSigDB FEX000038 Bladder Buytaert08 832genes Supplementary Table 1. PDT-induced up-regulated genes Significantly (p (more detail) 762 17952126 Homo sapiens

GeneSigDB TAX018241 GO:0010948 biological process negative regulation of cell cycle process Any process that decreases the rate, frequency or extent of a cellular process that is involved in t (more detail) 266 NA Homo sapiens

GOA IEI003383 Protein protein interactors of human gene DDA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDA1 (SwissProt ID=Q (more detail) 623 17535438 Homo sapiens

I2D TAX025313 GO:0045860 biological process positive regulation of protein kinase activity Any process that activates or increases the frequency, rate or extent of protein kinase activity. (more detail) 509 NA Homo sapiens

GOA TAX000360 Genes annotated by the GO term GO:0007275. The biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). (more detail) 1015 NA Homo sapiens

MSigDB IEI005683 Protein protein interactors of human gene H4C1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H4C1 (SwissProt ID=P (more detail) 292 17535438 Homo sapiens

I2D FEX002347 Lymphoma Gentles09 780genes Table S6. Genes that are repressed in nave memory cord blood cells relative to centroblasts and ce (more detail) 540 19636063 Homo sapiens

GeneSigDB TAX017173 GO:0008283 biological process cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population. (more detail) 649 NA Homo sapiens

GOA FEX000597 Breast Mutarelli08 1488genes Additional File 2-Selected gene list corresponding to the cluster analysis shown in Figure 2 and 3. (more detail) 1101 18387200 Homo sapiens

GeneSigDB IEI008993 Protein protein interactors of human gene NPM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NPM1 (SwissProt ID=P (more detail) 471 17535438 Homo sapiens

I2D MEX003766 Genes associated with Perturbagen Signature ouabain Genes associated with Perturbagen Signature ouabain, curated by the Drug Signature Database (DSigDB) (more detail) 663 25990557 Homo sapiens

DSigDB IEI006651 Protein protein interactors of human gene KBTBD7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KBTBD7 (SwissProt ID (more detail) 530 17535438 Homo sapiens

I2D GOX001662 Genes regulated by the microRNA hsa miR 30b 5p using target scan (more detail) 1481 NA Homo sapiens

TargetScan GOX001407 Genes regulated by the microRNA hsa miR 30c 5p using target scan (more detail) 1481 NA Homo sapiens

TargetScan GOX001419 Genes regulated by the microRNA hsa miR 30d 5p using target scan (more detail) 1481 NA Homo sapiens

TargetScan GOX001540 Genes regulated by the microRNA hsa miR 30e 5p using target scan (more detail) 1481 NA Homo sapiens

TargetScan GOX001368 Genes regulated by the microRNA hsa miR 30a 5p using target scan (more detail) 1481 NA Homo sapiens

TargetScan MEX001421 Genes associated with Kinase Inhibitor Crizotinib Genes associated with Kinase Inhibitor Crizotinib, curated by the Drug Signature Database (DSigDB). (more detail) 135 25990557 Homo sapiens

DSigDB TAX014538 GO:0003006 biological process developmental process involved in reproduction A developmental process in which a progressive change in the state of some part of an organism speci (more detail) 587 NA Homo sapiens

GOA MEX001551 Genes associated with Kinase Inhibitor AZD4547 Genes associated with Kinase Inhibitor AZD4547, curated by the Drug Signature Database (DSigDB). (more detail) 126 25990557 Homo sapiens

DSigDB FEX001153 Immune Kong10 5640genes ImmPort ComprehensiveListofImmune RelatedGenes ImmPort Comprehensive List of Immune-Related Genes (more detail) 4375 20460173 Homo sapiens

GeneSigDB FEX012605 The normalized gene expressions no less than 30 in the tissue of appendix from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 799 25613900 Homo sapiens

HPA-FANTOM5 TAX023711 GO:0042176 biological process regulation of protein catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 362 NA Homo sapiens

GOA FEX003496 Viral Cairo08 982genes Table S7. List of 824 genes (982 probe sets) differentially expressed between rC1 and rC2 subclasse (more detail) 754 19061838 Homo sapiens

GeneSigDB MAX001992 Genes constituting the PluriNet protein protein network shared by the pluripotent cells (embryonic stem cells, embryonical carcinomas and induced pluripotent cells). Stem cells are defined as self-renewing cell populations that can differentiate into multiple distin (more detail) 294 NA Homo sapiens

MSigDB TAX001358 Genes annotated by the GO term GO:0003723. Interacting selectively with an RNA molecule or a portion thereof. (more detail) 249 NA Homo sapiens

MSigDB IEI005679 Protein protein interactors of human gene H3 4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H3-4 (SwissProt ID=Q (more detail) 230 17535438 Homo sapiens

I2D IEI009710 Protein protein interactors of human gene PDPK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDPK1 (SwissProt ID= (more detail) 400 17535438 Homo sapiens

I2D MEX001881 Genes associated with Kinase Inhibitor K 252a, Nocardiopsis sp. Genes associated with Kinase Inhibitor K-252a, Nocardiopsis sp., curated by the Drug Signature Datab (more detail) 125 25990557 Homo sapiens

DSigDB TAX015895 GO:0005739 cellular component mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in th (more detail) 1146 NA Homo sapiens

GOA MAX000743 Genes down regulated in intestinal crypt cells upon deletion of CTNNB1 [GeneID=1499]. The Wnt signaling pathway is deregulated in over 90% of human colorectal cancers. beta-Catenin, the (more detail) 516 NA Homo sapiens

MSigDB MAX001296 Genes down regulated upon overexpression of PARVB [GeneID=29780] in MDA MB 231 cells (breast cancer) cultured in 3D Matrigel only. Parvin-beta is a focal adhesion protein downregulated in human breast cancer cells. Loss of Parvin-b (more detail) 818 NA Homo sapiens

MSigDB GOX001477 Genes regulated by the microRNA hsa miR 9 5p using target scan (more detail) 1294 NA Homo sapiens

TargetScan MOX000717 Genes associated with Computational Drug Signature arsenite Genes associated with Computational Drug Signature arsenite, curated by the Drug Signature Database (more detail) 1259 25990557 Homo sapiens

DSigDB TAX023871 GO:0042493 biological process response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 731 NA Homo sapiens

GOA TAX029504 GO:0071495 biological process cellular response to endogenous stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 686 NA Homo sapiens

GOA FEX012556 The normalized gene expressions no less than 30 in the tissue of endometrium from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 968 25613900 Homo sapiens

HPA-GTEx MOX005138 Genes associated with Computational Drug Signature menadione Genes associated with Computational Drug Signature menadione, curated by the Drug Signature Database (more detail) 1060 25990557 Homo sapiens

DSigDB TAX025275 GO:0045787 biological process positive regulation of cell cycle Any process that activates or increases the rate or extent of progression through the cell cycle. (more detail) 362 NA Homo sapiens

GOA TAX022249 GO:0033865 biological process nucleoside bisphosphate metabolic process The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a (more detail) 124 NA Homo sapiens

GOA TAX022276 GO:0034032 biological process purine nucleoside bisphosphate metabolic process The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consistin (more detail) 124 NA Homo sapiens

GOA TAX022255 GO:0033875 biological process ribonucleoside bisphosphate metabolic process The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting o (more detail) 124 NA Homo sapiens

GOA IEI011484 Protein protein interactors of human gene RPA3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPA3 (SwissProt ID=P (more detail) 380 17535438 Homo sapiens

I2D MOX000293 Genes associated with Computational Drug Signature Bisphenol A Genes associated with Computational Drug Signature Bisphenol A, curated by the Drug Signature Databa (more detail) 1209 25990557 Homo sapiens

DSigDB TAX024725 GO:0044389 molecular function ubiquitin like protein ligase binding Interacting selectively and non-covalently with a ubiquitin-like protein ligase, such as ubiquitin-l (more detail) 322 NA Homo sapiens

GOA MAX000984 Genes from common genomic gains observed in a meta analyis of copy number alterations across a panel of different cancer cell lines and tumor samples. Tumor-derived cell lines are used as in vitro cancer models, but their ability to accurately reflect (more detail) 311 NA Homo sapiens

MSigDB MEX001285 Genes associated with Kinase Inhibitor WH 4 023 Genes associated with Kinase Inhibitor WH-4-023, curated by the Drug Signature Database (DSigDB). (more detail) 136 25990557 Homo sapiens

DSigDB TAX024737 GO:0044419 biological process interspecies interaction between organisms Any process in which an organism has an effect on an organism of a different species. (more detail) 681 NA Homo sapiens

GOA MEX001848 Genes associated with Kinase Inhibitor Tg 101348 Genes associated with Kinase Inhibitor Tg-101348, curated by the Drug Signature Database (DSigDB). (more detail) 132 25990557 Homo sapiens

DSigDB IEI006117 Protein protein interactors of human gene HUWE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HUWE1 (SwissProt ID= (more detail) 411 17535438 Homo sapiens

I2D TAX031464 GO:0101005 molecular function ubiquitinyl hydrolase activity Catalysis of the hydrolysis of ubiquitin from proteins and other molecules. (more detail) 123 NA Homo sapiens

GOA TAX017133 GO:0008213 biological process protein alkylation The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an (more detail) 123 NA Homo sapiens

GOA TAX016361 GO:0006479 biological process protein methylation The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by th (more detail) 123 NA Homo sapiens

GOA GOX001547 Genes regulated by the microRNA hsa miR 144 3p using target scan (more detail) 988 NA Homo sapiens

TargetScan FEX012608 The normalized gene expressions no less than 30 in the tissue of testis from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1733 25613900 Homo sapiens

HPA-FANTOM5 IEI013239 Protein protein interactors of human gene SUZ12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUZ12 (SwissProt ID= (more detail) 354 17535438 Homo sapiens

I2D MOX005094 Genes associated with Computational Drug Signature genistein Genes associated with Computational Drug Signature genistein, curated by the Drug Signature Database (more detail) 1185 25990557 Homo sapiens

DSigDB FEX012529 The normalized gene expressions no less than 30 in the tissue of endometrium from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 667 25613900 Homo sapiens

HPA-normRNA FEX003043 StemCell Amundson08 990genes SuppTable 1. Genes responding to 8 Gy gamma-rays in at least 10% of cell lines (more detail) 908 18199535 Homo sapiens

GeneSigDB IEI012235 Protein protein interactors of human gene SIRT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIRT1 (SwissProt ID= (more detail) 314 17535438 Homo sapiens

I2D FEX009600 hsa miR 484 HITS-CLIP, Functional MTI (Weak) (more detail) 826 NA Homo sapiens

mirTARbase MAX000154 Set 'Sox2 targets': genes upregulated and identified by ChIP on chip as SOX2 [GeneID=6657] transcription factor targets in human embryonic stem cells. Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear, howev (more detail) 661 NA Homo sapiens

MSigDB TAX023391 GO:0036459 molecular function thiol dependent ubiquitinyl hydrolase activity Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bon (more detail) 122 NA Homo sapiens

GOA FEX012584 The normalized gene expressions no less than 30 in the tissue of spleen from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1180 25613900 Homo sapiens

HPA-FANTOM5 FEX003032 StemCell Nuytten08 1622genes Table S1. List of all genes with a significantly changed expression level after the knockdown of NIP (more detail) 1318 17724462 Homo sapiens

GeneSigDB TAX000427 Genes annotated by the GO term GO:0006807. The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium. (more detail) 148 NA Homo sapiens

MSigDB MEX004011 Genes associated with Perturbagen Signature puromycin Genes associated with Perturbagen Signature puromycin, curated by the Drug Signature Database (DSigD (more detail) 795 25990557 Homo sapiens

DSigDB TAX014210 GO:0002376 biological process immune system process Any process involved in the development or functioning of the immune system, an organismal system fo (more detail) 2289 NA Homo sapiens

GOA IEI014567 Protein protein interactors of human gene UBE2D2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2D2 (SwissProt ID (more detail) 211 17535438 Homo sapiens

I2D FEX012448 The normalized gene expressions no less than 30 in the tissue of small intestine. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1712 25613900 Homo sapiens

HPA-RNAcon FEX012469 The normalized gene expressions no less than 30 in the tissue of ductus deferens. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1024 25613900 Homo sapiens

HPA-RNAcon FEX012594 The normalized gene expressions no less than 30 in the tissue of ductus deferens from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1024 25613900 Homo sapiens

HPA-FANTOM5 TAX030571 GO:0090575 cellular component RNA polymerase II transcription factor complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymer (more detail) 141 NA Homo sapiens

GOA WIG000638 Ubiquitin mediated proteolysis Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions (more detail) 130 NA Homo sapiens

MSigDB FEX011570 hsa miR 193b 3p HITS-CLIP, Functional MTI (Weak) (more detail) 791 NA Homo sapiens

mirTARbase FEX012607 The normalized gene expressions no less than 30 in the tissue of smooth muscle from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1125 25613900 Homo sapiens

HPA-FANTOM5 MOX003964 Genes associated with Computational Drug Signature diclofenac Genes associated with Computational Drug Signature diclofenac, curated by the Drug Signature Databas (more detail) 422 25990557 Homo sapiens

DSigDB TAX017517 GO:0009116 biological process nucleoside metabolic process The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-rib (more detail) 121 NA Homo sapiens

GOA TAX000321 Genes annotated by the GO term GO:0009059. The chemical reactions and pathways resulting in the formation of macromolecules, large molecules including proteins, nucleic acids and carbohydrates. (more detail) 308 NA Homo sapiens

MSigDB IEI005943 Protein protein interactors of human gene HNRNPK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPK (SwissProt ID (more detail) 314 17535438 Homo sapiens

I2D FEX012561 The normalized gene expressions no less than 30 in the tissue of fallopian tube from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 606 25613900 Homo sapiens

HPA-GTEx FEX012436 The normalized gene expressions no less than 30 in the tissue of cervix, uterine. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1186 25613900 Homo sapiens

HPA-RNAcon IEI003386 Protein protein interactors of human gene DDB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDB1 (SwissProt ID=Q (more detail) 277 17535438 Homo sapiens

I2D TAX025155 GO:0045596 biological process negative regulation of cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. (more detail) 658 NA Homo sapiens

GOA FOX000578 Genes in the cancer module 252 (more detail) 229 NA Homo sapiens

MSigDB IEI013385 Protein protein interactors of human gene TARDBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TARDBP (SwissProt ID (more detail) 311 17535438 Homo sapiens

I2D MEX003639 Genes associated with Perturbagen Signature mitoxantrone Genes associated with Perturbagen Signature mitoxantrone, curated by the Drug Signature Database (DS (more detail) 657 25990557 Homo sapiens

DSigDB FEX012465 The normalized gene expressions no less than 30 in the tissue of midbrain. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1417 25613900 Homo sapiens

HPA-RNAcon WIG001841 Autophagy Autophagy, or Ãƒâ€šÃ¢â‚¬Å“self eatingÃƒâ€šÃ¢â‚¬Â¿, is the process by wh (more detail) 304 NA Homo sapiens

Spike IEI004945 Protein protein interactors of human gene FUS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FUS (SwissProt ID=P3 (more detail) 384 17535438 Homo sapiens

I2D FEX012468 The normalized gene expressions no less than 30 in the tissue of substantia nigra. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1418 25613900 Homo sapiens

HPA-RNAcon TAX016811 GO:0007167 biological process enzyme linked receptor protein signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on (more detail) 658 NA Homo sapiens

GOA FEX010053 hsa miR 20a 5p HITS-CLIP, Functional MTI (Weak) (more detail) 972 NA Homo sapiens

mirTARbase FEX012499 The normalized gene expressions no less than 30 in the tissue of thyroid gland from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 982 25613900 Homo sapiens

HPA-normRNA FAX000317 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif RTAAACA which matches annotation for FOXF2: forkhead box F2 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif RTAAACA (more detail) 853 NA Homo sapiens

MSigDB MEX003332 Genes associated with Perturbagen Signature helveticoside Genes associated with Perturbagen Signature helveticoside, curated by the Drug Signature Database (D (more detail) 612 25990557 Homo sapiens

DSigDB TAX021340 GO:0032101 biological process regulation of response to external stimulus Any process that modulates the frequency, rate or extent of a response to an external stimulus. (more detail) 790 NA Homo sapiens

GOA MEX004004 Genes associated with Perturbagen Signature proscillaridin Genes associated with Perturbagen Signature proscillaridin, curated by the Drug Signature Database ( (more detail) 499 25990557 Homo sapiens

DSigDB FAX000308 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif RCGCANGCGY which matches annotation for NRF1: nuclear respiratory factor 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif RCGCANGC (more detail) 823 NA Homo sapiens

MSigDB FEX012310 The genes express in high level in the celltype glandular cells in the rectum normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1416 25613900 Homo sapiens

HPA-normProtein FEX012470 The normalized gene expressions no less than 30 in the tissue of skin. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1188 25613900 Homo sapiens

HPA-RNAcon IEI014562 Protein protein interactors of human gene UBD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBD (SwissProt ID=O1 (more detail) 651 17535438 Homo sapiens

I2D FEX012466 The normalized gene expressions no less than 30 in the tissue of prostate. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1057 25613900 Homo sapiens

HPA-RNAcon FEX012303 The genes express in high level in the celltype glandular cells in the duodenum normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1481 25613900 Homo sapiens

HPA-normProtein FEX001245 Kidney Sallustio10 2134genes DiscriminatedARPCsFromRPTEC/MSC Supplemental Table 1. Gene expression values of 2134 gene probe sets corresponding to 1742 genes tha (more detail) 1598 19843711 Homo sapiens

GeneSigDB FEX012513 The normalized gene expressions no less than 30 in the tissue of adipose tissue from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1075 25613900 Homo sapiens

HPA-normRNA IEI006367 Protein protein interactors of human gene ILF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ILF3 (SwissProt ID=Q (more detail) 372 17535438 Homo sapiens

I2D FEX012304 The genes express in high level in the celltype glandular cells in the gallbladder normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1487 25613900 Homo sapiens

HPA-normProtein MAX001672 Genes up regulated in HeLa cells (cervical cancer) after simultaneus knockdown of all three MBD (methyl CpG binding domain) proteins MeCP2, MBD1 and MBD2 [GeneID=4204;4152;8932] by RNAi. Methyl-cytosine-phosphate-guanine (CpG)-binding domain (MBD) proteins are bound to hypermethylated p (more detail) 898 NA Homo sapiens

MSigDB FEX012497 The normalized gene expressions no less than 30 in the tissue of pancreas from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1024 25613900 Homo sapiens

HPA-normRNA FEX008709 hsa miR 106b 5p HITS-CLIP, Functional MTI (Weak) (more detail) 995 NA Homo sapiens

mirTARbase IEI003995 Protein protein interactors of human gene EGFR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EGFR (SwissProt ID=P (more detail) 1022 17535438 Homo sapiens

I2D TAX000072 Genes annotated by the GO term GO:0009056. The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. (more detail) 221 NA Homo sapiens

MSigDB MEX002438 Genes associated with Perturbagen Signature 0179445 0000 Genes associated with Perturbagen Signature 0179445-0000, curated by the Drug Signature Database (DS (more detail) 880 25990557 Homo sapiens

DSigDB MOX004507 Genes associated with Computational Drug Signature phenobarbital Genes associated with Computational Drug Signature phenobarbital, curated by the Drug Signature Data (more detail) 1094 25990557 Homo sapiens

DSigDB FEX012467 The normalized gene expressions no less than 30 in the tissue of spinal cord. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1384 25613900 Homo sapiens

HPA-RNAcon TAX013299 GO:0000184 biological process nuclear transcribed mRNA catabolic process, nonsense mediated decay The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-a (more detail) 117 NA Homo sapiens

GOA TAX015213 GO:0004540 molecular function ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. (more detail) 117 NA Homo sapiens

GOA MOX004712 Genes associated with Computational Drug Signature tamoxifen Genes associated with Computational Drug Signature tamoxifen, curated by the Drug Signature Database (more detail) 787 25990557 Homo sapiens

DSigDB FEX009020 hsa miR 155 5p HITS-CLIP, Functional MTI (Weak) (more detail) 839 NA Homo sapiens

mirTARbase MEX004171 Genes associated with Perturbagen Signature strophanthidin Genes associated with Perturbagen Signature strophanthidin, curated by the Drug Signature Database ( (more detail) 616 25990557 Homo sapiens

DSigDB TAX024351 GO:0043408 biological process regulation of MAPK cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP (more detail) 709 NA Homo sapiens

GOA FEX012552 The normalized gene expressions no less than 30 in the tissue of breast from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 709 25613900 Homo sapiens

HPA-GTEx TAX015911 GO:0005759 cellular component mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of (more detail) 352 NA Homo sapiens

GOA IEI003394 Protein protein interactors of human gene DDIT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDIT3 (SwissProt ID= (more detail) 380 17535438 Homo sapiens

I2D TAX023908 GO:0042578 molecular function phosphoric ester hydrolase activity Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosph (more detail) 370 NA Homo sapiens

GOA FEX001246 Kidney Sallustio10 2134genes CompleteListAnalysis Supplemental Table 2. Complete list of the analyzed genes branched for cluster. Six gene clusters ha (more detail) 1584 19843711 Homo sapiens

GeneSigDB IEI006070 Protein protein interactors of human gene HSPA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSPA4 (SwissProt ID= (more detail) 331 17535438 Homo sapiens

I2D GOX001504 Genes regulated by the microRNA hsa miR 429 using target scan (more detail) 1125 NA Homo sapiens

TargetScan GOX001656 Genes regulated by the microRNA hsa miR 200b 3p using target scan (more detail) 1125 NA Homo sapiens

TargetScan GOX001384 Genes regulated by the microRNA hsa miR 200c 3p using target scan (more detail) 1125 NA Homo sapiens

TargetScan FEX012495 The normalized gene expressions no less than 30 in the tissue of kidney from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1205 25613900 Homo sapiens

HPA-normRNA TAX017505 GO:0009100 biological process glycoprotein metabolic process The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bo (more detail) 116 NA Homo sapiens

GOA MEX001667 Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 116 25990557 Homo sapiens

DSigDB TAX019220 GO:0016791 molecular function phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. (more detail) 278 NA Homo sapiens

GOA GOX001557 Genes regulated by the microRNA hsa miR 424 5p using target scan (more detail) 1427 NA Homo sapiens

TargetScan TAX021950 GO:0033043 biological process regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arr (more detail) 1188 NA Homo sapiens

GOA GOX001747 Genes regulated by the microRNA hsa miR 101 3p.1 using target scan (more detail) 889 NA Homo sapiens

TargetScan TAX016044 GO:0005975 biological process carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds bas (more detail) 455 NA Homo sapiens

GOA GOX001581 Genes regulated by the microRNA hsa miR 6838 5p using target scan (more detail) 1425 NA Homo sapiens

TargetScan GOX001752 Genes regulated by the microRNA hsa miR 195 5p using target scan (more detail) 1425 NA Homo sapiens

TargetScan GOX001592 Genes regulated by the microRNA hsa miR 16 5p using target scan (more detail) 1425 NA Homo sapiens

TargetScan TAX000703 Genes annotated by the GO term GO:0006974. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. (more detail) 157 NA Homo sapiens

MSigDB TAX024146 GO:0043085 biological process positive regulation of catalytic activity Any process that activates or increases the activity of an enzyme. (more detail) 1361 NA Homo sapiens

GOA TAX015109 GO:0004386 molecular function helicase activity Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix (more detail) 154 NA Homo sapiens

GOA IEI003430 Protein protein interactors of human gene DDX5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX5 (SwissProt ID=P (more detail) 271 17535438 Homo sapiens

I2D TAX032892 GO:1903320 biological process regulation of protein modification by small protein conjugation or removal Any process that modulates the frequency, rate or extent of protein modification by small protein co (more detail) 214 NA Homo sapiens

GOA FEX002504 Breast Nagaraja10 1345genes Supplementary Table: up in clear cell (1345) (more detail) 962 20081105 Homo sapiens

GeneSigDB MAX000952 Up regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples. To characterize patterns of global transcriptional deregulation in primary colon carcinomas, we did (more detail) 781 NA Homo sapiens

MSigDB GOX001554 Genes regulated by the microRNA hsa miR 15a 5p using target scan (more detail) 1426 NA Homo sapiens

TargetScan GOX001569 Genes regulated by the microRNA hsa miR 497 5p using target scan (more detail) 1426 NA Homo sapiens

TargetScan GOX001568 Genes regulated by the microRNA hsa miR 15b 5p using target scan (more detail) 1426 NA Homo sapiens

TargetScan FEX012388 The genes express in medium or high level in at least 95% samples in liver cancer. Staining profiles for proteins in human tumor tissue based on immunohistochemisty using tissue micro (more detail) 1152 28818916 Homo sapiens

HPA-PathologyAtlas IEI004303 Protein protein interactors of human gene ESR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ESR2 (SwissProt ID=Q (more detail) 496 17535438 Homo sapiens

I2D FEX012539 The normalized gene expressions no less than 30 in the tissue of spleen from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 1095 25613900 Homo sapiens

HPA-GTEx TAX000720 Genes annotated by the GO term GO:0006950. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). (more detail) 494 NA Homo sapiens

MSigDB TAX021080 GO:0031625 molecular function ubiquitin protein ligase binding Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 pro (more detail) 309 NA Homo sapiens

GOA TAX030035 GO:0072524 biological process pyridine containing compound metabolic process The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that (more detail) 115 NA Homo sapiens

GOA TAX032324 GO:1901987 biological process regulation of cell cycle phase transition Any process that modulates the frequency, rate or extent of cell cycle phase transition. (more detail) 376 NA Homo sapiens

GOA FEX012577 The normalized gene expressions no less than 30 in the tissue of kidney from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1389 25613900 Homo sapiens

HPA-FANTOM5 IEI012951 Protein protein interactors of human gene SQSTM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SQSTM1 (SwissProt ID (more detail) 562 17535438 Homo sapiens

I2D TAX024594 GO:0044092 biological process negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biologica (more detail) 1089 NA Homo sapiens

GOA TAX014427 GO:0002764 biological process immune response regulating signaling pathway The cascade of processes by which a signal interacts with a receptor, causing a change in the level (more detail) 482 NA Homo sapiens

GOA WAG000376 Purine metabolism (more detail) 144 NA Homo sapiens

KEGG TAX017175 GO:0008285 biological process negative regulation of cell proliferation Any process that stops, prevents or reduces the rate or extent of cell proliferation. (more detail) 654 NA Homo sapiens

GOA TAX026770 GO:0051054 biological process positive regulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 208 NA Homo sapiens

GOA IEI012781 Protein protein interactors of human gene SOX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOX2 (SwissProt ID=P (more detail) 337 17535438 Homo sapiens

I2D WIG001821 ATM Signaling Network Ataxia telangiectasia mutated (ATM) is a serine/threonine-specific protein kinase that is recruited (more detail) 198 NA Homo sapiens

Spike FEX012537 The normalized gene expressions no less than 30 in the tissue of pancreas from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 975 25613900 Homo sapiens

HPA-GTEx TAX014420 GO:0002757 biological process immune response activating signal transduction The cascade of processes by which a signal interacts with a receptor, causing a change in the level (more detail) 449 NA Homo sapiens

GOA GOX001675 Genes regulated by the microRNA hsa miR 519d 3p using target scan (more detail) 1315 NA Homo sapiens

TargetScan FEX012486 The normalized gene expressions no less than 30 in the tissue of fallopian tube. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1000 25613900 Homo sapiens

HPA-RNAcon TAX026816 GO:0051130 biological process positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of a process involved in the f (more detail) 1151 NA Homo sapiens

GOA TAX017479 GO:0009063 biological process cellular amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids contain (more detail) 114 NA Homo sapiens

GOA GOX001426 Genes regulated by the microRNA hsa miR 3681 3p using target scan (more detail) 1149 NA Homo sapiens

TargetScan GOX001512 Genes regulated by the microRNA hsa miR 216a 3p using target scan (more detail) 1149 NA Homo sapiens

TargetScan GOX001699 Genes regulated by the microRNA hsa miR 128 3p using target scan (more detail) 1149 NA Homo sapiens

TargetScan TAX020548 GO:0030522 biological process intracellular receptor signaling pathway Any series of molecular signals initiated by a ligand binding to an receptor located within a cell. (more detail) 169 NA Homo sapiens

GOA MOX003792 Genes associated with Computational Drug Signature carbamazepine Genes associated with Computational Drug Signature carbamazepine, curated by the Drug Signature Data (more detail) 431 25990557 Homo sapiens

DSigDB TAX020931 GO:0031331 biological process positive regulation of cellular catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 338 NA Homo sapiens

GOA GOX001428 Genes regulated by the microRNA hsa miR 526b 3p using target scan (more detail) 1314 NA Homo sapiens

TargetScan MEX002644 Genes associated with Perturbagen Signature azacitidine Genes associated with Perturbagen Signature azacitidine, curated by the Drug Signature Database (DSi (more detail) 802 25990557 Homo sapiens

DSigDB MEX004012 Genes associated with Perturbagen Signature puromycin Genes associated with Perturbagen Signature puromycin, curated by the Drug Signature Database (DSigD (more detail) 919 25990557 Homo sapiens

DSigDB GOX001360 Genes regulated by the microRNA hsa miR 106b 5p using target scan (more detail) 1312 NA Homo sapiens

TargetScan GOX001472 Genes regulated by the microRNA hsa miR 17 5p using target scan (more detail) 1312 NA Homo sapiens

TargetScan GOX001517 Genes regulated by the microRNA hsa miR 106a 5p using target scan (more detail) 1312 NA Homo sapiens

TargetScan GOX001375 Genes regulated by the microRNA hsa miR 93 5p using target scan (more detail) 1312 NA Homo sapiens

TargetScan GOX001673 Genes regulated by the microRNA hsa miR 20a 5p using target scan (more detail) 1312 NA Homo sapiens

TargetScan GOX001424 Genes regulated by the microRNA hsa miR 20b 5p using target scan (more detail) 1312 NA Homo sapiens

TargetScan IEI011614 Protein protein interactors of human gene RPS8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS8 (SwissProt ID=P (more detail) 221 17535438 Homo sapiens

I2D MEX002317 Genes associated with Kinase Inhibitor CGP74514A Genes associated with Kinase Inhibitor CGP74514A, curated by the Drug Signature Database (DSigDB). (more detail) 122 25990557 Homo sapiens

DSigDB FEX012331 The genes express in high level in the celltype neuronal cells in the cerebral cortex normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 893 25613900 Homo sapiens

HPA-normProtein IEI003946 Protein protein interactors of human gene EEF1A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EEF1A1 (SwissProt ID (more detail) 407 17535438 Homo sapiens

I2D TAX017510 GO:0009108 biological process coenzyme biosynthetic process The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprote (more detail) 171 NA Homo sapiens

GOA MEX002864 Genes associated with Perturbagen Signature cimetidine Genes associated with Perturbagen Signature cimetidine, curated by the Drug Signature Database (DSig (more detail) 896 25990557 Homo sapiens

DSigDB TAX015036 GO:0004222 molecular function metalloendopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism i (more detail) 113 NA Homo sapiens

GOA TAX016357 GO:0006475 biological process internal protein amino acid acetylation The addition of an acetyl group to a non-terminal amino acid in a protein. (more detail) 113 NA Homo sapiens

GOA TAX000032 Genes annotated by the GO term GO:0048856. The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. (more detail) 981 NA Homo sapiens

MSigDB TAX033086 GO:1903706 biological process regulation of hemopoiesis Any process that modulates the frequency, rate or extent of hemopoiesis. (more detail) 379 NA Homo sapiens

GOA TAX018239 GO:0010942 biological process positive regulation of cell death Any process that increases the rate or frequency of cell death. Cell death is the specific activatio (more detail) 640 NA Homo sapiens

GOA IEI009034 Protein protein interactors of human gene NR3C1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR3C1 (SwissProt ID= (more detail) 227 17535438 Homo sapiens

I2D MEX002327 Genes associated with Kinase Inhibitor Midostaurin Genes associated with Kinase Inhibitor Midostaurin, curated by the Drug Signature Database (DSigDB). (more detail) 125 25990557 Homo sapiens

DSigDB FEX012300 The genes express in high level in the celltype glandular cells in the colon normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1333 25613900 Homo sapiens

HPA-normProtein FEX000907 Colon Grade07 1102genes SuppTable3. Differentially expressed genes between 30 colon tumors and matched mucosa samples (P (more detail) 781 17210682 Homo sapiens

GeneSigDB TAX000079 Genes annotated by the GO term GO:0044248. The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. (more detail) 208 NA Homo sapiens

MSigDB FEX012527 The normalized gene expressions no less than 30 in the tissue of breast from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 723 25613900 Homo sapiens

HPA-normRNA WAG000988 Ubiquitin mediated proteolysis Protein ubiquitition plays an important role in eukaryotic cellular processes. It mainly functions a (more detail) 121 NA Homo sapiens

KEGG IEI007683 Protein protein interactors of human gene MAPK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPK1 (SwissProt ID= (more detail) 299 17535438 Homo sapiens

I2D IEI012590 Protein protein interactors of human gene SMARCA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCA4 (SwissProt I (more detail) 222 17535438 Homo sapiens

I2D IEI014856 Protein protein interactors of human gene VCP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VCP (SwissProt ID=P5 (more detail) 558 17535438 Homo sapiens

I2D FEX012570 The normalized gene expressions no less than 30 in the tissue of adipose tissue from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1164 25613900 Homo sapiens

HPA-FANTOM5 FEX000978 Embryo Heim07 2325genes Supplementary Table 2 (more detail) 1476 17880687 Homo sapiens

GeneSigDB IEI015146 Protein protein interactors of human gene YBX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YBX1 (SwissProt ID=P (more detail) 382 17535438 Homo sapiens

I2D IEI007639 Protein protein interactors of human gene MAP1LC3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP1LC3A (SwissProt (more detail) 521 17535438 Homo sapiens

I2D TAX019272 GO:0016874 molecular function ligase activity Catalysis of the joining of two substances, or two groups within a single molecule, with the concomi (more detail) 141 NA Homo sapiens

GOA TAX001198 Genes annotated by the GO term GO:0016788. Catalysis of the hydrolysis of any ester bond. (more detail) 262 NA Homo sapiens

MSigDB TAX028670 GO:0065003 biological process protein containing complex assembly The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-conta (more detail) 1429 NA Homo sapiens

GOA TAX032455 GO:1902275 biological process regulation of chromatin organization Any process that modulates the frequency, rate or extent of chromatin organization. (more detail) 161 NA Homo sapiens

GOA TAX025315 GO:0045862 biological process positive regulation of proteolysis Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide (more detail) 335 NA Homo sapiens

GOA IEI014568 Protein protein interactors of human gene UBE2D3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2D3 (SwissProt ID (more detail) 202 17535438 Homo sapiens

I2D FEX012481 The normalized gene expressions no less than 30 in the tissue of gallbladder. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1109 25613900 Homo sapiens

HPA-RNAcon TAX000022 Genes annotated by the GO term GO:0009308. The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. (more detail) 134 NA Homo sapiens

MSigDB FEX012490 The normalized gene expressions no less than 30 in the tissue of adrenal gland from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1045 25613900 Homo sapiens

HPA-normRNA FEX012494 The normalized gene expressions no less than 30 in the tissue of heart muscle from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1420 25613900 Homo sapiens

HPA-normRNA MOX000780 Genes associated with Computational Drug Signature 4 Hydroxytamoxifen Genes associated with Computational Drug Signature 4-Hydroxytamoxifen, curated by the Drug Signature (more detail) 569 25990557 Homo sapiens

DSigDB WEX000059 MAPK Signaling The genes related to mapk signaling (signaling pathways) in tumor, immune, stroma using next-generat (more detail) 261 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas TAX017023 GO:0008033 biological process tRNA processing The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an ami (more detail) 111 NA Homo sapiens

GOA TAX017146 GO:0008238 molecular function exopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus (more detail) 111 NA Homo sapiens

GOA WIG000603 Purine metabolism (more detail) 149 NA Homo sapiens

MSigDB MAX000140 Genes showing cell cycle stage specific expression [PMID=12058064]. Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear, howev (more detail) 599 NA Homo sapiens

MSigDB IEI005681 Protein protein interactors of human gene H3C1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H3C1 (SwissProt ID=P (more detail) 213 17535438 Homo sapiens

I2D TAX000181 Genes annotated by the GO term GO:0006281. The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double strand break repair pathway, and mismatch repair pathway. (more detail) 123 NA Homo sapiens

MSigDB TAX020669 GO:0030855 biological process epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial (more detail) 307 NA Homo sapiens

GOA TAX025583 GO:0046467 biological process membrane lipid biosynthetic process The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found i (more detail) 119 NA Homo sapiens

GOA MEX001279 Genes associated with Kinase Inhibitor AGN PC 04XSRZ Genes associated with Kinase Inhibitor AGN-PC-04XSRZ, curated by the Drug Signature Database (DSigDB (more detail) 119 25990557 Homo sapiens

DSigDB FEX012583 The normalized gene expressions no less than 30 in the tissue of small intestine from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1535 25613900 Homo sapiens

HPA-FANTOM5 IEI013159 Protein protein interactors of human gene STUB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STUB1 (SwissProt ID= (more detail) 273 17535438 Homo sapiens

I2D MAX003095 Genes whose promoters contain E box motifs and whose expression changed in MYCN 3 cells (neuroblastoma) upon induction of MYCN [GeneID=4613]. Loss of 1p36 heterozygosity commonly occurs with MYCN amplification in neuroblastoma tumors, and bot (more detail) 714 NA Homo sapiens

MSigDB FEX002682 Prostate John Aryankalayil09 2212genes Table S3 Differentially expressed genes showing (more detail) 1452 19139136 Homo sapiens

GeneSigDB IEI004054 Protein protein interactors of human gene EIF4A3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF4A3 (SwissProt ID (more detail) 275 17535438 Homo sapiens

I2D MOX004840 Genes associated with Computational Drug Signature vincristine Genes associated with Computational Drug Signature vincristine, curated by the Drug Signature Databa (more detail) 1191 25990557 Homo sapiens

DSigDB TAX019531 GO:0018394 biological process peptidyl lysine acetylation The acetylation of peptidyl-lysine. (more detail) 110 NA Homo sapiens

GOA IEI008630 Protein protein interactors of human gene NCL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCL (SwissProt ID=P1 (more detail) 298 17535438 Homo sapiens

I2D IEI002183 Protein protein interactors of human gene CDC37 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC37 (SwissProt ID= (more detail) 279 17535438 Homo sapiens

I2D TAX019231 GO:0016810 molecular function hydrolase activity, acting on carbon nitrogen (but not peptide) bonds Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. (more detail) 145 NA Homo sapiens

GOA FEX012479 The normalized gene expressions no less than 30 in the tissue of colon. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1516 25613900 Homo sapiens

HPA-RNAcon FEX012534 The normalized gene expressions no less than 30 in the tissue of heart muscle from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 1235 25613900 Homo sapiens

HPA-GTEx IEI015132 Protein protein interactors of human gene XRCC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XRCC5 (SwissProt ID= (more detail) 255 17535438 Homo sapiens

I2D TAX023613 GO:0040029 biological process regulation of gene expression, epigenetic Any process that modulates the frequency, rate or extent of gene expression; the process is mitotica (more detail) 159 NA Homo sapiens

GOA TAX017996 GO:0010608 biological process posttranscriptional regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression after the production of (more detail) 421 NA Homo sapiens

GOA TAX001152 Genes annotated by the GO term GO:0004175. Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides, and comprising any enzyme of sub subclasses EC:3.4.21 99. They are classfied according to the presence of essential catalytic residues or ions at their active sites. (more detail) 114 NA Homo sapiens

MSigDB MEX002025 Genes associated with Kinase Inhibitor PD173955 Genes associated with Kinase Inhibitor PD173955, curated by the Drug Signature Database (DSigDB). (more detail) 114 25990557 Homo sapiens

DSigDB MOX003072 Genes associated with Computational Drug Signature Vorinostat Genes associated with Computational Drug Signature Vorinostat, curated by the Drug Signature Databas (more detail) 417 25990557 Homo sapiens

DSigDB GOX001655 Genes regulated by the microRNA hsa miR 203a 3p.1 using target scan (more detail) 1033 NA Homo sapiens

TargetScan FEX012610 The normalized gene expressions no less than 30 in the tissue of prostate from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 765 25613900 Homo sapiens

HPA-FANTOM5 TAX017750 GO:0009725 biological process response to hormone Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 638 NA Homo sapiens

GOA WIG001819 Response to DSBs DNA double-strand breaks (DSBs) arise in cells from and exogenous and endogenous attacks on the DNA (more detail) 164 NA Homo sapiens

Spike IEI012790 Protein protein interactors of human gene SP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SP1 (SwissProt ID=P0 (more detail) 297 17535438 Homo sapiens

I2D TAX017522 GO:0009124 biological process nucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a comp (more detail) 109 NA Homo sapiens

GOA MEX003029 Genes associated with Perturbagen Signature digoxigenin Genes associated with Perturbagen Signature digoxigenin, curated by the Drug Signature Database (DSi (more detail) 475 25990557 Homo sapiens

DSigDB IEI012224 Protein protein interactors of human gene SIN3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIN3A (SwissProt ID= (more detail) 199 17535438 Homo sapiens

I2D MEX001869 Genes associated with Kinase Inhibitor Dabrafenib Genes associated with Kinase Inhibitor Dabrafenib, curated by the Drug Signature Database (DSigDB). (more detail) 121 25990557 Homo sapiens

DSigDB MEX002416 Genes associated with Kinase Inhibitor Dabrafenib Genes associated with Kinase Inhibitor Dabrafenib, curated by the Drug Signature Database (DSigDB). (more detail) 121 25990557 Homo sapiens

DSigDB TAX020968 GO:0031400 biological process negative regulation of protein modification process Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteratio (more detail) 586 NA Homo sapiens

GOA MEX003030 Genes associated with Perturbagen Signature digoxigenin Genes associated with Perturbagen Signature digoxigenin, curated by the Drug Signature Database (DSi (more detail) 761 25990557 Homo sapiens

DSigDB FEX012507 The normalized gene expressions no less than 30 in the tissue of skin from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 902 25613900 Homo sapiens

HPA-normRNA FEX012492 The normalized gene expressions no less than 30 in the tissue of epididymis from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1162 25613900 Homo sapiens

HPA-normRNA IEI003161 Protein protein interactors of human gene CUL4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUL4B (SwissProt ID= (more detail) 310 17535438 Homo sapiens

I2D TAX025404 GO:0046034 biological process ATP metabolic process The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important c (more detail) 108 NA Homo sapiens

GOA TAX025603 GO:0046496 biological process nicotinamide nucleotide metabolic process The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains (more detail) 108 NA Homo sapiens

GOA TAX019691 GO:0019362 biological process pyridine nucleotide metabolic process The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a (more detail) 108 NA Homo sapiens

GOA MEX001267 Genes associated with Kinase Inhibitor OTSSP167 Genes associated with Kinase Inhibitor OTSSP167, curated by the Drug Signature Database (DSigDB). (more detail) 108 25990557 Homo sapiens

DSigDB TAX021263 GO:0031982 cellular component vesicle Any small, fluid-filled, spherical organelle enclosed by membrane. (more detail) 3043 NA Homo sapiens

GOA MEX003532 Genes associated with Perturbagen Signature medrysone Genes associated with Perturbagen Signature medrysone, curated by the Drug Signature Database (DSigD (more detail) 720 25990557 Homo sapiens

DSigDB FEX012560 The normalized gene expressions no less than 30 in the tissue of thyroid gland from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 697 25613900 Homo sapiens

HPA-GTEx MAX001769 Genes down regulated in NB4 cells (acute promyelocytic leukemia, APL) in response to tretinoin [PubChem=444795]; based on Chip seq data. Many different molecular mechanisms have been associated with PML-RARalpha-dependent transformation (more detail) 739 NA Homo sapiens

MSigDB FEX012575 The normalized gene expressions no less than 30 in the tissue of esophagus from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1192 25613900 Homo sapiens

HPA-FANTOM5 FEX012595 The normalized gene expressions no less than 30 in the tissue of midbrain from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 975 25613900 Homo sapiens

HPA-FANTOM5 IEI004993 Protein protein interactors of human gene GABARAPL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GABARAPL2 (SwissProt (more detail) 588 17535438 Homo sapiens

I2D IEI004381 Protein protein interactors of human gene EZH2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EZH2 (SwissProt ID=Q (more detail) 267 17535438 Homo sapiens

I2D IEI014232 Protein protein interactors of human gene TRIM28 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM28 (SwissProt ID (more detail) 269 17535438 Homo sapiens

I2D TAX020832 GO:0031123 biological process RNA 3' end processing Any process involved in forming the mature 3' end of an RNA molecule. (more detail) 107 NA Homo sapiens

GOA TAX019530 GO:0018393 biological process internal peptidyl lysine acetylation The addition of an acetyl group to a non-terminal lysine residue in a protein. (more detail) 107 NA Homo sapiens

GOA TAX032979 GO:1903510 biological process mucopolysaccharide metabolic process The chemical reactions and pathways involving mucopolysaccharide. (more detail) 107 NA Homo sapiens

GOA TAX032077 GO:1901292 biological process nucleoside phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate. (more detail) 107 NA Homo sapiens

GOA IEI013090 Protein protein interactors of human gene STAT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAT3 (SwissProt ID= (more detail) 296 17535438 Homo sapiens

I2D FEX012457 The normalized gene expressions no less than 30 in the tissue of lung. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1199 25613900 Homo sapiens

HPA-RNAcon IEI011715 Protein protein interactors of human gene RUVBL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RUVBL2 (SwissProt ID (more detail) 260 17535438 Homo sapiens

I2D MEX002608 Genes associated with Perturbagen Signature ampyrone Genes associated with Perturbagen Signature ampyrone, curated by the Drug Signature Database (DSigDB (more detail) 734 25990557 Homo sapiens

DSigDB FEX012599 The normalized gene expressions no less than 30 in the tissue of endometrium from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 836 25613900 Homo sapiens

HPA-FANTOM5 TAX017792 GO:0009888 biological process tissue development The process whose specific outcome is the progression of a tissue over time, from its formation to t (more detail) 576 NA Homo sapiens

GOA FEX012569 The normalized gene expressions no less than 30 in the tissue of salivary gland from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1162 25613900 Homo sapiens

HPA-FANTOM5 MEX000804 Genes associated with Approved Drug sorafenib Genes associated with Approved Drug sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 115 25990557 Homo sapiens

DSigDB FOX000572 Genes in the cancer module 244 (more detail) 179 NA Homo sapiens

MSigDB FEX012517 The normalized gene expressions no less than 30 in the tissue of b cells from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 968 25613900 Homo sapiens

HPA-normRNA FEX012478 The normalized gene expressions no less than 30 in the tissue of b cells. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 968 25613900 Homo sapiens

HPA-RNAcon GOX001652 Genes regulated by the microRNA hsa miR 340 5p using target scan (more detail) 1321 NA Homo sapiens

TargetScan TAX026795 GO:0051098 biological process regulation of binding Any process that modulates the frequency, rate or extent of binding, the selective interaction of a (more detail) 352 NA Homo sapiens

GOA TAX032773 GO:1903047 biological process mitotic cell cycle process A process that is part of the mitotic cell cycle. (more detail) 568 NA Homo sapiens

GOA TAX018828 GO:0016032 biological process viral process A multi-organism process in which a virus is a participant. The other participant is the host. Inclu (more detail) 493 NA Homo sapiens

GOA TAX024729 GO:0044403 biological process symbiont process A process carried out by symbiont gene products that enables a symbiotic interaction with a host org (more detail) 493 NA Homo sapiens

GOA TAX016676 GO:0006915 biological process apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or e (more detail) 629 NA Homo sapiens

GOA IEI003550 Protein protein interactors of human gene DHX9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHX9 (SwissProt ID=Q (more detail) 301 17535438 Homo sapiens

I2D TAX026193 GO:0048511 biological process rhythmic process Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism. (more detail) 248 NA Homo sapiens

GOA IEI008795 Protein protein interactors of human gene NFKB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFKB1 (SwissProt ID= (more detail) 315 17535438 Homo sapiens

I2D GOX001441 Genes regulated by the microRNA hsa miR 130a 3p using target scan (more detail) 980 NA Homo sapiens

TargetScan GOX001398 Genes regulated by the microRNA hsa miR 454 3p using target scan (more detail) 980 NA Homo sapiens

TargetScan GOX001572 Genes regulated by the microRNA hsa miR 301a 3p using target scan (more detail) 980 NA Homo sapiens

TargetScan GOX001433 Genes regulated by the microRNA hsa miR 4295 using target scan (more detail) 980 NA Homo sapiens

TargetScan GOX001363 Genes regulated by the microRNA hsa miR 301b 3p using target scan (more detail) 980 NA Homo sapiens

TargetScan GOX001754 Genes regulated by the microRNA hsa miR 130b 3p using target scan (more detail) 980 NA Homo sapiens

TargetScan GOX001582 Genes regulated by the microRNA hsa miR 3666 using target scan (more detail) 980 NA Homo sapiens

TargetScan TAX026319 GO:0048732 biological process gland development The process whose specific outcome is the progression of a gland over time, from its formation to th (more detail) 241 NA Homo sapiens

GOA FEX002467 Ovarian Baranova06 907genes SertoliLeydig Supplementary Table 1. list of 907 genes representing Sertoli Leydig ovarian tumor signature (more detail) 815 17177833 Homo sapiens

GeneSigDB MEX000922 Genes associated with Approved Drug vandetanib Genes associated with Approved Drug vandetanib, curated by the Drug Signature Database (DSigDB). (more detail) 114 25990557 Homo sapiens

DSigDB FEX000421 Breast Bertucci06 2537genes Suppl. Table 2: List of probe sets included in the 14 gene clusters shown in Figure 1 (more detail) 1538 16651414 Homo sapiens

GeneSigDB IEI001229 Protein protein interactors of human gene BARD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BARD1 (SwissProt ID= (more detail) 256 17535438 Homo sapiens

I2D FEX012284 The genes express in high level in the celltype trophoblastic cells in the placenta normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1128 25613900 Homo sapiens

HPA-normProtein TAX013605 GO:0001078 molecular function proximal promoter DNA binding transcription repressor activity, RNA polymerase II specific A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA (more detail) 134 NA Homo sapiens

GOA FEX012564 The normalized gene expressions no less than 30 in the tissue of skin from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 903 25613900 Homo sapiens

HPA-GTEx IEI011598 Protein protein interactors of human gene RPS4X from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS4X (SwissProt ID= (more detail) 236 17535438 Homo sapiens

I2D FEX000030 Bladder Osman06 1054genes SupplementTable1. List of DEGs without high correlation to age and gender (1 054) from supervised Wi (more detail) 727 16740760 Homo sapiens

GeneSigDB IEI006072 Protein protein interactors of human gene HSPA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSPA5 (SwissProt ID= (more detail) 377 17535438 Homo sapiens

I2D IEI011004 Protein protein interactors of human gene RARA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RARA (SwissProt ID=P (more detail) 169 17535438 Homo sapiens

I2D TAX019192 GO:0016746 molecular function transferase activity, transferring acyl groups Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). (more detail) 246 NA Homo sapiens

GOA FEX009542 hsa miR 186 5p HITS-CLIP, Functional MTI (Weak) (more detail) 693 NA Homo sapiens

mirTARbase FEX012542 The normalized gene expressions no less than 30 in the tissue of urinary bladder from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 707 25613900 Homo sapiens

HPA-GTEx TAX024141 GO:0043068 biological process positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death, cell (more detail) 590 NA Homo sapiens

GOA MAX001444 Genes down regulated in HL 60 cells (acute promyelocytic leukemia, APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR 2797) [PubChem=15547703] for 24 h. CHR-2797 is a novel metalloenzyme inhibitor that is converted into a pharmacologically active acid p (more detail) 896 NA Homo sapiens

MSigDB MOX003781 Genes associated with Computational Drug Signature calcitriol Genes associated with Computational Drug Signature calcitriol, curated by the Drug Signature Databas (more detail) 1872 25990557 Homo sapiens

DSigDB MEX001047 Genes associated with Approved Drug axitinib Genes associated with Approved Drug axitinib, curated by the Drug Signature Database (DSigDB). (more detail) 104 25990557 Homo sapiens

DSigDB FOX000454 Genes in the cancer module 123 (more detail) 239 NA Homo sapiens

MSigDB WIG000620 Spliceosome After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. (more detail) 123 NA Homo sapiens

MSigDB TAX014783 GO:0003735 molecular function structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome. (more detail) 163 NA Homo sapiens

GOA WIG000882 Genes involved in Glycosaminoglycan metabolism (more detail) 108 NA Homo sapiens

MSigDB FAX000263 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif CTTTAAR. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif CTTTAAR. Mot (more detail) 888 NA Homo sapiens

MSigDB IEI000451 Protein protein interactors of human gene AKT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKT1 (SwissProt ID=P (more detail) 352 17535438 Homo sapiens

I2D IEI003957 Protein protein interactors of human gene EEF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EEF2 (SwissProt ID=P (more detail) 216 17535438 Homo sapiens

I2D IEI015133 Protein protein interactors of human gene XRCC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XRCC6 (SwissProt ID= (more detail) 320 17535438 Homo sapiens

I2D IEI010644 Protein protein interactors of human gene PSMC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMC5 (SwissProt ID= (more detail) 178 17535438 Homo sapiens

I2D FEX012510 The normalized gene expressions no less than 30 in the tissue of salivary gland from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1004 25613900 Homo sapiens

HPA-normRNA TAX026644 GO:0050865 biological process regulation of cell activation Any process that modulates the frequency, rate or extent of cell activation, the change in the morph (more detail) 558 NA Homo sapiens

GOA TAX000508 Genes annotated by the GO term GO:0045935. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. (more detail) 152 NA Homo sapiens

MSigDB MEX003112 Genes associated with Perturbagen Signature ellipticine Genes associated with Perturbagen Signature ellipticine, curated by the Drug Signature Database (DSi (more detail) 759 25990557 Homo sapiens

DSigDB TAX026555 GO:0050727 biological process regulation of inflammatory response Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate (more detail) 402 NA Homo sapiens

GOA FEX012554 The normalized gene expressions no less than 30 in the tissue of cervix, uterine from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 631 25613900 Homo sapiens

HPA-GTEx IEI013449 Protein protein interactors of human gene TBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBP (SwissProt ID=P2 (more detail) 165 17535438 Homo sapiens

I2D TAX022270 GO:0033993 biological process response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 717 NA Homo sapiens

GOA IEI011602 Protein protein interactors of human gene RPS6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS6 (SwissProt ID=P (more detail) 220 17535438 Homo sapiens

I2D FEX012473 The normalized gene expressions no less than 30 in the tissue of amygdala. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1289 25613900 Homo sapiens

HPA-RNAcon TAX032885 GO:1903311 biological process regulation of mRNA metabolic process Any process that modulates the frequency, rate or extent of mRNA metabolic process. (more detail) 242 NA Homo sapiens

GOA FEX012460 The normalized gene expressions no less than 30 in the tissue of total pbmc. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1093 25613900 Homo sapiens

HPA-RNAcon MAX000554 Common down regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [GeneID=2071], after UVC irradiation. Xeroderma pigmentosum (XP) and trichothiodystrophy (TTD) syndromes are characterized by deficiency i (more detail) 460 NA Homo sapiens

MSigDB TAX000506 Genes annotated by the GO term GO:0009893. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. (more detail) 233 NA Homo sapiens

MSigDB IEI008844 Protein protein interactors of human gene NIPSNAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NIPSNAP2 (SwissProt (more detail) 575 17535438 Homo sapiens

I2D MOX001273 Genes associated with Computational Drug Signature Enterolactone Genes associated with Computational Drug Signature Enterolactone, curated by the Drug Signature Data (more detail) 927 25990557 Homo sapiens

DSigDB MAX002152 Genes down regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [GeneID=2146] by RNAi. EZH2 is a Polycomb group (PcG) protein that promotes the late-stage development of cancer by silenci (more detail) 915 NA Homo sapiens

MSigDB FEX000991 EmbryonicStemCell Thomas08 113genes Supplementary Table 6. Common transcription factors to hNCC and hES3/4; hNCC tpm with hNCC count in (more detail) 111 18689800 Homo sapiens

GeneSigDB TAX035007 GO:2001020 biological process regulation of response to DNA damage stimulus Any process that modulates the frequency, rate or extent of response to DNA damage stimulus. (more detail) 189 NA Homo sapiens

GOA TAX015346 GO:0004725 molecular function protein tyrosine phosphatase activity Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. (more detail) 102 NA Homo sapiens

GOA TAX029734 GO:0071897 biological process DNA biosynthetic process The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of (more detail) 102 NA Homo sapiens

GOA TAX022824 GO:0035335 biological process peptidyl tyrosine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine. (more detail) 102 NA Homo sapiens

GOA TAX019099 GO:0016573 biological process histone acetylation The modification of a histone by the addition of an acetyl group. (more detail) 102 NA Homo sapiens

GOA TAX016234 GO:0006289 biological process nucleotide excision repair A DNA repair process in which a small region of the strand surrounding the damage is removed from th (more detail) 102 NA Homo sapiens

GOA TAX016079 GO:0006023 biological process aminoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containi (more detail) 102 NA Homo sapiens

GOA TAX017138 GO:0008219 biological process cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell (more detail) 810 NA Homo sapiens

GOA FEX000295 Breast Dairkee04 681genes SuppTable 2. Table S2: SAM identification of 681 differentially expressed genes in group 1 comprised (more detail) 479 15260889 Homo sapiens

GeneSigDB IEI009083 Protein protein interactors of human gene NSMAF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NSMAF (SwissProt ID= (more detail) 375 17535438 Homo sapiens

I2D IEI006366 Protein protein interactors of human gene ILF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ILF2 (SwissProt ID=Q (more detail) 281 17535438 Homo sapiens

I2D TAX025562 GO:0046434 biological process organophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-co (more detail) 153 NA Homo sapiens

GOA TAX000705 Genes annotated by the GO term GO:0009719. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endogenous stimulus. (more detail) 193 NA Homo sapiens

MSigDB IEI011583 Protein protein interactors of human gene RPS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS2 (SwissProt ID=P (more detail) 236 17535438 Homo sapiens

I2D TAX000409 Genes annotated by the GO term GO:0045892. Any process that stops, prevents or reduces the frequency, rate or extent of DNA dependent transcription. (more detail) 127 NA Homo sapiens

MSigDB FEX012563 The normalized gene expressions no less than 30 in the tissue of prostate from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 542 25613900 Homo sapiens

HPA-GTEx MAX002338 Genes constituting the BRCA2 PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient, PCC >= 0.4) with that of BRCA2 [GeneID=675] across a compendium of normal tissues. Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms (more detail) 403 NA Homo sapiens

MSigDB FEX012514 The normalized gene expressions no less than 30 in the tissue of appendix from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 594 25613900 Homo sapiens

HPA-normRNA FEX012296 The genes express in high level in the celltype glandular cells in the adrenal gland normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1167 25613900 Homo sapiens

HPA-normProtein TAX017563 GO:0009166 biological process nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that i (more detail) 101 NA Homo sapiens

GOA TAX016080 GO:0006024 biological process glycosaminoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group (more detail) 101 NA Homo sapiens

GOA MEX001932 Genes associated with Kinase Inhibitor Crizotinib Genes associated with Kinase Inhibitor Crizotinib, curated by the Drug Signature Database (DSigDB). (more detail) 101 25990557 Homo sapiens

DSigDB TAX001018 Genes annotated by the GO term GO:0043234. Any protein group composed of two or more subunits, which may or may not be identical. Protein complexes may have other associated non protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups. (more detail) 791 NA Homo sapiens

MSigDB IEI014548 Protein protein interactors of human gene UBA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBA5 (SwissProt ID=Q (more detail) 536 17535438 Homo sapiens

I2D GOX001427 Genes regulated by the microRNA hsa let 7a 5p using target scan (more detail) 1122 NA Homo sapiens

TargetScan GOX001670 Genes regulated by the microRNA hsa let 7g 5p using target scan (more detail) 1122 NA Homo sapiens

TargetScan GOX001508 Genes regulated by the microRNA hsa let 7d 5p using target scan (more detail) 1122 NA Homo sapiens

TargetScan GOX001408 Genes regulated by the microRNA hsa miR 98 5p using target scan (more detail) 1122 NA Homo sapiens

TargetScan GOX001756 Genes regulated by the microRNA hsa let 7c 5p using target scan (more detail) 1122 NA Homo sapiens

TargetScan GOX001458 Genes regulated by the microRNA hsa let 7i 5p using target scan (more detail) 1122 NA Homo sapiens

TargetScan GOX001402 Genes regulated by the microRNA hsa let 7e 5p using target scan (more detail) 1122 NA Homo sapiens

TargetScan GOX001562 Genes regulated by the microRNA hsa let 7b 5p using target scan (more detail) 1122 NA Homo sapiens

TargetScan GOX001603 Genes regulated by the microRNA hsa miR 4500 using target scan (more detail) 1122 NA Homo sapiens

TargetScan GOX001643 Genes regulated by the microRNA hsa miR 4458 using target scan (more detail) 1122 NA Homo sapiens

TargetScan GOX001391 Genes regulated by the microRNA hsa let 7f 5p using target scan (more detail) 1122 NA Homo sapiens

TargetScan TAX017791 GO:0009887 biological process animal organ morphogenesis Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work togeth (more detail) 438 NA Homo sapiens

GOA TAX026266 GO:0048646 biological process anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of an anatomical structure from unspec (more detail) 676 NA Homo sapiens

GOA TAX000481 Genes annotated by the GO term GO:0031325. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. (more detail) 226 NA Homo sapiens

MSigDB WIG001002 Genes involved in mRNA Splicing (more detail) 105 NA Homo sapiens

MSigDB FEX012603 The normalized gene expressions no less than 30 in the tissue of gallbladder from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 990 25613900 Homo sapiens

HPA-FANTOM5 TAX024138 GO:0043065 biological process positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of cell death by apoptotic pro (more detail) 584 NA Homo sapiens

GOA WIG001825 DNA damage response and chromatin remodeling The packaging of eukaryotic chromosomal DNA into nucleosomes impedes the access of the DNA repair ma (more detail) 157 NA Homo sapiens

Spike IEI011546 Protein protein interactors of human gene RPL6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL6 (SwissProt ID=Q (more detail) 217 17535438 Homo sapiens

I2D TAX021363 GO:0032147 biological process activation of protein kinase activity Any process that initiates the activity of an inactive protein kinase. (more detail) 304 NA Homo sapiens

GOA TAX024348 GO:0043405 biological process regulation of MAP kinase activity Any process that modulates the frequency, rate or extent of MAP kinase activity. (more detail) 338 NA Homo sapiens

GOA TAX000405 Genes annotated by the GO term GO:0051253. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. (more detail) 129 NA Homo sapiens

MSigDB WIG001820 Nucleotide excision repair Nucleotide excision repair (NER) is a particularly important mechanism by which the cell can prevent (more detail) 132 NA Homo sapiens

Spike TAX023600 GO:0040008 biological process regulation of growth Any process that modulates the frequency, rate or extent of the growth of all or part of an organism (more detail) 644 NA Homo sapiens

GOA TAX022817 GO:0035326 molecular function enhancer binding Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that (more detail) 116 NA Homo sapiens

GOA TAX032774 GO:1903050 biological process regulation of proteolysis involved in cellular protein catabolic process Any process that modulates the frequency, rate or extent of proteolysis involved in cellular protein (more detail) 210 NA Homo sapiens

GOA TAX015880 GO:0005694 cellular component chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that car (more detail) 196 NA Homo sapiens

GOA TAX017554 GO:0009156 biological process ribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a (more detail) 100 NA Homo sapiens

GOA MEX001715 Genes associated with Kinase Inhibitor PHA 767491 Genes associated with Kinase Inhibitor PHA-767491, curated by the Drug Signature Database (DSigDB). (more detail) 100 25990557 Homo sapiens

DSigDB TAX016371 GO:0006493 biological process protein O linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to (more detail) 100 NA Homo sapiens

GOA MEX002187 Genes associated with Kinase Inhibitor Antibiotic K 252a Genes associated with Kinase Inhibitor Antibiotic K 252a, curated by the Drug Signature Database (DS (more detail) 100 25990557 Homo sapiens

DSigDB FEX012493 The normalized gene expressions no less than 30 in the tissue of esophagus from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 984 25613900 Homo sapiens

HPA-normRNA FEX012596 The normalized gene expressions no less than 30 in the tissue of thalamus from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 837 25613900 Homo sapiens

HPA-FANTOM5 FEX012471 The normalized gene expressions no less than 30 in the tissue of thalamus. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 837 25613900 Homo sapiens

HPA-RNAcon TAX019199 GO:0016758 molecular function transferase activity, transferring hexosyl groups Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). (more detail) 207 NA Homo sapiens

GOA IEI011596 Protein protein interactors of human gene RPS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS3 (SwissProt ID=P (more detail) 270 17535438 Homo sapiens

I2D IEI002264 Protein protein interactors of human gene CDK9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK9 (SwissProt ID=P (more detail) 193 17535438 Homo sapiens

I2D FEX012568 The normalized gene expressions no less than 30 in the tissue of pons and medulla from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 1376 25613900 Homo sapiens

HPA-FANTOM5 FEX012573 The normalized gene expressions no less than 30 in the tissue of cervix, uterine from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 899 25613900 Homo sapiens

HPA-FANTOM5 IEI005482 Protein protein interactors of human gene GRB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRB2 (SwissProt ID=P (more detail) 1023 17535438 Homo sapiens

I2D FOX000527 Genes in the cancer module 197 (more detail) 171 NA Homo sapiens

MSigDB MAX002438 Genes up regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue. Information on gene alterations associated to poorly differentiated (PDTC) and anaplastic thyroid ca (more detail) 658 NA Homo sapiens

MSigDB FEX012429 The normalized gene expressions no less than 30 in the tissue of pons and medulla. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1375 25613900 Homo sapiens

HPA-RNAcon MOX004547 Genes associated with Computational Drug Signature piroxicam Genes associated with Computational Drug Signature piroxicam, curated by the Drug Signature Database (more detail) 535 25990557 Homo sapiens

DSigDB TAX032327 GO:1901990 biological process regulation of mitotic cell cycle phase transition Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition. (more detail) 344 NA Homo sapiens

GOA FEX012562 The normalized gene expressions no less than 30 in the tissue of pituitary gland from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 689 25613900 Homo sapiens

HPA-GTEx TAX019872 GO:0019900 molecular function kinase binding Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of (more detail) 675 NA Homo sapiens

GOA IEI003889 Protein protein interactors of human gene E2F1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene E2F1 (SwissProt ID=Q (more detail) 168 17535438 Homo sapiens

I2D IEI001025 Protein protein interactors of human gene ATG101 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATG101 (SwissProt ID (more detail) 558 17535438 Homo sapiens

I2D IEI011543 Protein protein interactors of human gene RPL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL4 (SwissProt ID=P (more detail) 215 17535438 Homo sapiens

I2D IEI012080 Protein protein interactors of human gene SF3A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SF3A2 (SwissProt ID= (more detail) 136 17535438 Homo sapiens

I2D FEX012342 The genes express in high level in the celltype glandular cells in the thyroid gland normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 926 25613900 Homo sapiens

HPA-normProtein IEI011578 Protein protein interactors of human gene RPS16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS16 (SwissProt ID= (more detail) 217 17535438 Homo sapiens

I2D WIG001974 mRNA processing mRNA processing (more detail) 127 NA Homo sapiens

WikiPathway MEX001316 Genes associated with Kinase Inhibitor 405169 16 6 Genes associated with Kinase Inhibitor 405169-16-6, curated by the Drug Signature Database (DSigDB). (more detail) 103 25990557 Homo sapiens

DSigDB TAX020964 GO:0031396 biological process regulation of protein ubiquitination Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a pr (more detail) 187 NA Homo sapiens

GOA MAX000195 Genes down regulated in brain from patients with Alzheimer's disease. The pathogenesis of incipient Alzheimer's disease (AD) has been resistant to analysis because of the (more detail) 1158 NA Homo sapiens

MSigDB TAX018284 GO:0012501 biological process programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of (more detail) 769 NA Homo sapiens

GOA TAX016703 GO:0006959 biological process humoral immune response An immune response mediated through a body fluid. (more detail) 295 NA Homo sapiens

GOA FEX008755 hsa miR 15a 5p HITS-CLIP, Functional MTI (Weak) (more detail) 651 NA Homo sapiens

mirTARbase IEI002270 Protein protein interactors of human gene CDKN1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDKN1A (SwissProt ID (more detail) 297 17535438 Homo sapiens

I2D TAX022679 GO:0034976 biological process response to endoplasmic reticulum stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 232 NA Homo sapiens

GOA GOX001502 Genes regulated by the microRNA hsa miR 23c using target scan (more detail) 1251 NA Homo sapiens

TargetScan GOX001511 Genes regulated by the microRNA hsa miR 23a 3p using target scan (more detail) 1251 NA Homo sapiens

TargetScan GOX001725 Genes regulated by the microRNA hsa miR 23b 3p using target scan (more detail) 1251 NA Homo sapiens

TargetScan GOX001371 Genes regulated by the microRNA hsa miR 130a 5p using target scan (more detail) 1251 NA Homo sapiens

TargetScan GOX001621 Genes regulated by the microRNA hsa miR 1 3p using target scan (more detail) 837 NA Homo sapiens

TargetScan GOX001758 Genes regulated by the microRNA hsa miR 206 using target scan (more detail) 837 NA Homo sapiens

TargetScan FEX012523 The normalized gene expressions no less than 30 in the tissue of placenta from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 950 25613900 Homo sapiens

HPA-normRNA FEX012526 The normalized gene expressions no less than 30 in the tissue of rectum from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 859 25613900 Homo sapiens

HPA-normRNA FEX012485 The normalized gene expressions no less than 30 in the tissue of rectum. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 859 25613900 Homo sapiens

HPA-RNAcon GOX001387 Genes regulated by the microRNA hsa miR 381 3p using target scan (more detail) 784 NA Homo sapiens

TargetScan GOX001541 Genes regulated by the microRNA hsa miR 300 using target scan (more detail) 784 NA Homo sapiens

TargetScan TAX028695 GO:0070035 molecular function purine NTP dependent helicase activity Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DN (more detail) 98 NA Homo sapiens

GOA TAX017021 GO:0008026 molecular function ATP dependent helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix (more detail) 98 NA Homo sapiens

GOA TAX014768 GO:0003705 molecular function transcription factor activity, RNA polymerase II distal enhancer sequence specific binding Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer regio (more detail) 98 NA Homo sapiens

GOA TAX020187 GO:0022607 biological process cellular component assembly The aggregation, arrangement and bonding together of a cellular component. (more detail) 2202 NA Homo sapiens

GOA MEX004161 Genes associated with Perturbagen Signature staurosporine Genes associated with Perturbagen Signature staurosporine, curated by the Drug Signature Database (D (more detail) 631 25990557 Homo sapiens

DSigDB FEX012450 The normalized gene expressions no less than 30 in the tissue of stomach. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 916 25613900 Homo sapiens

HPA-RNAcon TAX026896 GO:0051249 biological process regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of lymphocyte activation. (more detail) 447 NA Homo sapiens

GOA MEX002097 Genes associated with Kinase Inhibitor 1092351 67 1 Genes associated with Kinase Inhibitor 1092351-67-1, curated by the Drug Signature Database (DSigDB) (more detail) 120 25990557 Homo sapiens

DSigDB GOX001661 Genes regulated by the microRNA hsa miR 613 using target scan (more detail) 838 NA Homo sapiens

TargetScan FAX000303 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif MGGAAGTG which matches annotation for GABPA: GA binding protein transcription factor, alpha subunit 60kDa
GABPB2: GA binding protein transcription factor, beta subunit 2 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif MGGAAGTG (more detail) 704 NA Homo sapiens

MSigDB TAX013486 GO:0000781 cellular component chromosome, telomeric region The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated pr (more detail) 132 NA Homo sapiens

GOA FEX012530 The normalized gene expressions no less than 30 in the tissue of fallopian tube from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 831 25613900 Homo sapiens

HPA-normRNA MOX002008 Genes associated with Computational Drug Signature Irinotecan hydrochloride Genes associated with Computational Drug Signature Irinotecan hydrochloride, curated by the Drug Sig (more detail) 547 25990557 Homo sapiens

DSigDB IEI006075 Protein protein interactors of human gene HSPA8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSPA8 (SwissProt ID= (more detail) 411 17535438 Homo sapiens

I2D WIG001822 Repair of Interstrand Crosslinks Multiple pathways of DNA repair participate in the repair of DNA interstrand cross-links (ICLs). The (more detail) 102 NA Homo sapiens

Spike IEI012990 Protein protein interactors of human gene SRRM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRRM2 (SwissProt ID= (more detail) 211 17535438 Homo sapiens

I2D TAX027788 GO:0060284 biological process regulation of cell development Any process that modulates the rate, frequency or extent of the progression of the cell over time, f (more detail) 852 NA Homo sapiens

GOA TAX022392 GO:0034248 biological process regulation of cellular amide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 376 NA Homo sapiens

GOA MEX003202 Genes associated with Perturbagen Signature fisetin Genes associated with Perturbagen Signature fisetin, curated by the Drug Signature Database (DSigDB) (more detail) 519 25990557 Homo sapiens

DSigDB TAX028544 GO:0061695 cellular component transferase complex, transferring phosphorus containing groups A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one (more detail) 190 NA Homo sapiens

GOA TAX017519 GO:0009119 biological process ribonucleoside metabolic process The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or py (more detail) 97 NA Homo sapiens

GOA TAX032181 GO:1901606 biological process alpha amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid. (more detail) 97 NA Homo sapiens

GOA IEI011517 Protein protein interactors of human gene RPL23 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL23 (SwissProt ID= (more detail) 206 17535438 Homo sapiens

I2D TAX032907 GO:1903362 biological process regulation of cellular protein catabolic process Any process that modulates the frequency, rate or extent of cellular protein catabolic process. (more detail) 241 NA Homo sapiens

GOA FEX010718 hsa miR 124 3p HITS-CLIP, Functional MTI (Weak) (more detail) 1347 NA Homo sapiens

mirTARbase IEI004658 Protein protein interactors of human gene FBXO6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO6 (SwissProt ID= (more detail) 592 17535438 Homo sapiens

I2D TAX001417 Genes annotated by the GO term GO:0003713. The function of a transcription cofactor that activates transcription from a RNA polymerase II promoter; does not bind DNA itself. (more detail) 122 NA Homo sapiens

MSigDB IEI012578 Protein protein interactors of human gene SMAD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMAD2 (SwissProt ID= (more detail) 385 17535438 Homo sapiens

I2D TAX014374 GO:0002694 biological process regulation of leukocyte activation Any process that modulates the frequency, rate, or extent of leukocyte activation. (more detail) 522 NA Homo sapiens

GOA FEX012559 The normalized gene expressions no less than 30 in the tissue of salivary gland from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 747 25613900 Homo sapiens

HPA-GTEx TAX000520 Genes annotated by the GO term GO:0045941. Any process that activates or increases the frequency, rate or extent of transcription. (more detail) 142 NA Homo sapiens

MSigDB IEI012955 Protein protein interactors of human gene SRC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRC (SwissProt ID=P1 (more detail) 476 17535438 Homo sapiens

I2D FAX000264 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif CTTTGA which matches annotation for LEF1: lymphoid enhancer binding factor 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif CTTTGA w (more detail) 1124 NA Homo sapiens

MSigDB WIG001733 MAPK Signaling MAPK Signaling (more detail) 342 NA Homo sapiens

Protein Lounge GOX001392 Genes regulated by the microRNA hsa miR 25 3p using target scan (more detail) 973 NA Homo sapiens

TargetScan GOX001695 Genes regulated by the microRNA hsa miR 363 3p using target scan (more detail) 973 NA Homo sapiens

TargetScan GOX001509 Genes regulated by the microRNA hsa miR 92a 3p using target scan (more detail) 973 NA Homo sapiens

TargetScan GOX001727 Genes regulated by the microRNA hsa miR 367 3p using target scan (more detail) 973 NA Homo sapiens

TargetScan GOX001574 Genes regulated by the microRNA hsa miR 92b 3p using target scan (more detail) 973 NA Homo sapiens

TargetScan GOX001515 Genes regulated by the microRNA hsa miR 32 5p using target scan (more detail) 973 NA Homo sapiens

TargetScan IEI008639 Protein protein interactors of human gene NCOR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCOR1 (SwissProt ID= (more detail) 165 17535438 Homo sapiens

I2D IEI002854 Protein protein interactors of human gene COPS6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COPS6 (SwissProt ID= (more detail) 292 17535438 Homo sapiens

I2D MEX003456 Genes associated with Perturbagen Signature lanatoside C Genes associated with Perturbagen Signature lanatoside C, curated by the Drug Signature Database (DS (more detail) 934 25990557 Homo sapiens

DSigDB FEX000240 Breast van 2460 probesets. Genes that co-regulate with the ER- alpha gene (/ESR1)/. (more detail) 1807 11823860 Homo sapiens

GeneSigDB TAX000322 Genes annotated by the GO term GO:0009057. The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates. (more detail) 133 NA Homo sapiens

MSigDB MAX002719 Genes down regulated in lymphoblastoid cells from the European population compared to those from the Asian population. Variation in DNA sequence contributes to individual differences in quantitative traits, but in human (more detail) 562 NA Homo sapiens

MSigDB WIG000557 MAPK signaling pathway The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in (more detail) 265 NA Homo sapiens

MSigDB GOX001702 Genes regulated by the microRNA hsa miR 137 using target scan (more detail) 1234 NA Homo sapiens

TargetScan IEI006632 Protein protein interactors of human gene KAT2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KAT2B (SwissProt ID= (more detail) 186 17535438 Homo sapiens

I2D TAX001024 Genes annotated by the GO term GO:0030529. A macromolecular complex containing both protein and RNA molecules. (more detail) 141 NA Homo sapiens

MSigDB TAX000780 Genes annotated by the GO term GO:0048731. The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. (more detail) 832 NA Homo sapiens

MSigDB FEX012518 The normalized gene expressions no less than 30 in the tissue of cervix, uterine from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 784 25613900 Homo sapiens

HPA-normRNA MOX000264 Genes associated with Computational Drug Signature Pirinixic acid Genes associated with Computational Drug Signature Pirinixic acid, curated by the Drug Signature Dat (more detail) 1353 25990557 Homo sapiens

DSigDB TAX025352 GO:0045930 biological process negative regulation of mitotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the mitotic ce (more detail) 241 NA Homo sapiens

GOA MEX001872 Genes associated with Kinase Inhibitor Cdk1/2 Inhibitor III Genes associated with Kinase Inhibitor Cdk1/2 Inhibitor III, curated by the Drug Signature Database (more detail) 95 25990557 Homo sapiens

DSigDB FEX012557 The normalized gene expressions no less than 30 in the tissue of vagina from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 718 25613900 Homo sapiens

HPA-GTEx IEI011577 Protein protein interactors of human gene RPS15A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS15A (SwissProt ID (more detail) 208 17535438 Homo sapiens

I2D TAX017368 GO:0008610 biological process lipid biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an or (more detail) 562 NA Homo sapiens

GOA FEX012553 The normalized gene expressions no less than 30 in the tissue of kidney from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 817 25613900 Homo sapiens

HPA-GTEx TAX000451 Genes annotated by the GO term GO:0048513. Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. (more detail) 553 NA Homo sapiens

MSigDB FEX003081 StemCell Kumamoto08 2005genes Supplementary Table. S1 Up-regulated genes by nutlin-3a-induced p53 (more detail) 1279 18451145 Homo sapiens

GeneSigDB IEI011597 Protein protein interactors of human gene RPS3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS3A (SwissProt ID= (more detail) 201 17535438 Homo sapiens

I2D TAX027001 GO:0051427 molecular function hormone receptor binding Interacting selectively and non-covalently with a receptor for hormones. (more detail) 173 NA Homo sapiens

GOA IEI015058 Protein protein interactors of human gene WIPI2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WIPI2 (SwissProt ID= (more detail) 551 17535438 Homo sapiens

I2D MEX002223 Genes associated with Kinase Inhibitor CHEMBL1908395 Genes associated with Kinase Inhibitor CHEMBL1908395, curated by the Drug Signature Database (DSigDB (more detail) 99 25990557 Homo sapiens

DSigDB TAX020779 GO:0031056 biological process regulation of histone modification Any process that modulates the frequency, rate or extent of the covalent alteration of a histone. (more detail) 134 NA Homo sapiens

GOA TAX024748 GO:0044432 cellular component endoplasmic reticulum part Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible (more detail) 1289 NA Homo sapiens

GOA IEI011572 Protein protein interactors of human gene RPS11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS11 (SwissProt ID= (more detail) 155 17535438 Homo sapiens

I2D TAX030038 GO:0072527 biological process pyrimidine containing compound metabolic process The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound th (more detail) 94 NA Homo sapiens

GOA TAX014377 GO:0002697 biological process regulation of immune effector process Any process that modulates the frequency, rate, or extent of an immune effector process. (more detail) 413 NA Homo sapiens

GOA WIG000678 Genes involved in Adaptive Immune System (more detail) 512 NA Homo sapiens

MSigDB FEX012283 The genes express in high level in the celltype respiratory epithelial cells in the nasopharynx normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1003 25613900 Homo sapiens

HPA-normProtein FEX012606 The normalized gene expressions no less than 30 in the tissue of lung from the Function Annotation of the Mammalian Genome project. Transcript expression levels summarized per gene in 60 tissues based on CAGE data. The tab-separated (more detail) 988 25613900 Homo sapiens

HPA-FANTOM5 FEX012546 The normalized gene expressions no less than 30 in the tissue of spinal cord from the Gene Tissue Expression project. Transcript expression levels summarized per gene in 36 tissues based on RNA-seq. The tab-separated f (more detail) 1143 25613900 Homo sapiens

HPA-GTEx IEI004992 Protein protein interactors of human gene GABARAPL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GABARAPL1 (SwissProt (more detail) 585 17535438 Homo sapiens

I2D FEX012315 The genes express in high level in the celltype glandular cells in the stomach 2 normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1218 25613900 Homo sapiens

HPA-normProtein IEI011051 Protein protein interactors of human gene RBBP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBBP4 (SwissProt ID= (more detail) 202 17535438 Homo sapiens

I2D FEX012317 The genes express in high level in the celltype cells in seminiferous ducts in the testis normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 946 25613900 Homo sapiens

HPA-normProtein FEX012314 The genes express in high level in the celltype glandular cells in the stomach 1 normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1239 25613900 Homo sapiens

HPA-normProtein TAX035126 GO:2001252 biological process positive regulation of chromosome organization Any process that activates or increases the frequency, rate or extent of chromosome organization. (more detail) 157 NA Homo sapiens

GOA TAX029255 GO:0071013 cellular component catalytic step 2 spliceosome A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in (more detail) 98 NA Homo sapiens

GOA WAG000395 Pyrimidine metabolism (more detail) 98 NA Homo sapiens

KEGG MOX004733 Genes associated with Computational Drug Signature Phorbol 12 myristate 13 acetate Genes associated with Computational Drug Signature Phorbol 12-myristate 13-acetate, curated by the D (more detail) 477 25990557 Homo sapiens

DSigDB TAX026174 GO:0048468 biological process cell development The process whose specific outcome is the progression of the cell over time, from its formation to t (more detail) 618 NA Homo sapiens

GOA TAX022786 GO:0035257 molecular function nuclear hormone receptor binding Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent recep (more detail) 149 NA Homo sapiens

GOA FAX000293 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif GTGACGY which matches annotation for E4F1: E4F transcription factor 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif GTGACGY (more detail) 600 NA Homo sapiens

MSigDB IEI011087 Protein protein interactors of human gene RBM39 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM39 (SwissProt ID= (more detail) 164 17535438 Homo sapiens

I2D WIG000744 Genes involved in Cell Cycle Checkpoints (more detail) 112 NA Homo sapiens

MSigDB WIG001963 MAPK signaling pathway MAPK signaling pathway (more detail) 159 NA Homo sapiens

WikiPathway IEI012651 Protein protein interactors of human gene SMURF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMURF1 (SwissProt ID (more detail) 312 17535438 Homo sapiens

I2D MEX003162 Genes associated with Perturbagen Signature etifenin Genes associated with Perturbagen Signature etifenin, curated by the Drug Signature Database (DSigDB (more detail) 591 25990557 Homo sapiens

DSigDB WIG000977 Genes involved in Metabolism of lipids and lipoproteins (more detail) 458 NA Homo sapiens

MSigDB WAG001564 mRNA Splicing Major Pathway (more detail) 93 NA Homo sapiens

Reactome TAX032325 GO:1901988 biological process negative regulation of cell cycle phase transition Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transi (more detail) 171 NA Homo sapiens

GOA TAX013346 GO:0000287 molecular function magnesium ion binding Interacting selectively and non-covalently with magnesium (Mg) ions. (more detail) 201 NA Homo sapiens

GOA FEX016542 The diagnosis of Solid carcinoma, NOS (stage ia) in Upper lobe, lung (TCGA 69 8255 FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 335 25613900 Homo sapiens

HPA-TCGA TAX024727 GO:0044391 cellular component ribosomal subunit Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit (more detail) 194 NA Homo sapiens

GOA WIG000978 Genes involved in Metabolism of mRNA (more detail) 269 NA Homo sapiens

MSigDB FEX012508 The normalized gene expressions no less than 30 in the tissue of duodenum from the Human Protein Atlas. Transcript expression levels summarized per gene in 37 tissues based on RNA-seq. The tab-separated f (more detail) 1010 25613900 Homo sapiens

HPA-normRNA FEX012472 The normalized gene expressions no less than 30 in the tissue of duodenum. Consensus transcript expression levels summarized per gene in 62 tissues based on transcriptomics da (more detail) 1010 25613900 Homo sapiens

HPA-RNAcon TAX019193 GO:0016747 molecular function transferase activity, transferring acyl groups other than amino acyl groups Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to anot (more detail) 216 NA Homo sapiens

GOA TAX022304 GO:0034097 biological process response to cytokine Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 515 NA Homo sapiens

GOA IEI014877 Protein protein interactors of human gene VHL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VHL (SwissProt ID=P4 (more detail) 414 17535438 Homo sapiens

I2D MEX001763 Genes associated with Kinase Inhibitor PKR Inhibitor Genes associated with Kinase Inhibitor PKR Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 92 25990557 Homo sapiens

DSigDB TAX017540 GO:0009142 biological process nucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compo (more detail) 92 NA Homo sapiens

GOA IEI011503 Protein protein interactors of human gene RPL11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL11 (SwissProt ID= (more detail) 222 17535438 Homo sapiens

I2D WAG000604 Glycan structures biosynthesis 1 (more detail) 104 NA Homo sapiens

KEGG MEX002384 Genes associated with Kinase Inhibitor A 443654 Genes associated with Kinase Inhibitor A-443654, curated by the Drug Signature Database (DSigDB). (more detail) 104 25990557 Homo sapiens

DSigDB MEX001460 Genes associated with Kinase Inhibitor CP 466722 Genes associated with Kinase Inhibitor CP-466722, curated by the Drug Signature Database (DSigDB). (more detail) 117 25990557 Homo sapiens

DSigDB IEI015180 Protein protein interactors of human gene YWHAQ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YWHAQ (SwissProt ID= (more detail) 467 17535438 Homo sapiens

I2D IEI012261 Protein protein interactors of human gene SKP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SKP1 (SwissProt ID=P (more detail) 193 17535438 Homo sapiens

I2D IEI011511 Protein protein interactors of human gene RPL18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL18 (SwissProt ID= (more detail) 193 17535438 Homo sapiens

I2D IEI004599 Protein protein interactors of human gene FBL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBL (SwissProt ID=P2 (more detail) 155 17535438 Homo sapiens

I2D IEI012580 Protein protein interactors of human gene SMAD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMAD4 (SwissProt ID= (more detail) 276 17535438 Homo sapiens

I2D FOX000634 Genes in the cancer module 32 (more detail) 228 NA Homo sapiens

MSigDB IEI009923 Protein protein interactors of human gene PIK3C2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIK3C2A (SwissProt I (more detail) 385 17535438 Homo sapiens

I2D WIG001261 Genes involved in S Phase (more detail) 107 NA Homo sapiens

MSigDB IEI015182 Protein protein interactors of human gene YY1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YY1 (SwissProt ID=P2 (more detail) 147 17535438 Homo sapiens

I2D IEI013112 Protein protein interactors of human gene STK11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STK11 (SwissProt ID= (more detail) 381 17535438 Homo sapiens

I2D IEI010471 Protein protein interactors of human gene PRKAB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRKAB2 (SwissProt ID (more detail) 542 17535438 Homo sapiens

I2D IEI011714 Protein protein interactors of human gene RUVBL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RUVBL1 (SwissProt ID (more detail) 238 17535438 Homo sapiens

I2D TAX019210 GO:0016779 molecular function nucleotidyltransferase activity Catalysis of the transfer of a nucleotidyl group to a reactant. (more detail) 136 NA Homo sapiens

GOA WIG001832 Apoptosis In The Ear Cell death in inner ear tissues is an important mechanism leading to hearing impairment. Members of (more detail) 225 NA Homo sapiens

Spike WIG001095 Genes involved in Post translational protein modification (more detail) 178 NA Homo sapiens

MSigDB TAX023077 GO:0035770 cellular component ribonucleoprotein granule A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA (more detail) 203 NA Homo sapiens

GOA WIG000993 Genes involved in Mitotic G1 G1/S phases (more detail) 133 NA Homo sapiens

MSigDB MAX000854 Genes down regulated in Daudi cells (B lymphocytes) stably expressing CD5 [GeneID=921] off a plasmid vector. Chronic lymphocytic leukemia (CLL) results in the accumulation of B cells, presumably reflecting the (more detail) 410 NA Homo sapiens

MSigDB TAX017100 GO:0008170 molecular function N methyltransferase activity Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. (more detail) 95 NA Homo sapiens

GOA IEI012082 Protein protein interactors of human gene SF3B1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SF3B1 (SwissProt ID= (more detail) 161 17535438 Homo sapiens

I2D TAX000753 Genes annotated by the GO term GO:0007165. The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell. (more detail) 1595 NA Homo sapiens

MSigDB FEX001594 Leukemia Pellegrini08 2692genes Supplementary Table 1. genes most significantly bound by CREB and differentially expressed in our kn (more detail) 1989 18801183 Homo sapiens

GeneSigDB TAX016757 GO:0007049 biological process cell cycle The progression of biochemical and morphological phases and events that occur in a cell during succe (more detail) 426 NA Homo sapiens

GOA FEX000296 Breast Dairkee04 479genes Table S2a. SAM identification of 681 differentially expressed genes in group 1 comprised of immortal (more detail) 345 15260889 Homo sapiens

GeneSigDB IEI011724 Protein protein interactors of human gene RXRA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RXRA (SwissProt ID=P (more detail) 135 17535438 Homo sapiens

I2D TAX029739 GO:0071902 biological process positive regulation of protein serine/threonine kinase activity Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activit (more detail) 337 NA Homo sapiens

GOA WIG000800 Genes involved in DNA Repair (more detail) 102 NA Homo sapiens

MSigDB TAX013625 GO:0001158 molecular function enhancer sequence specific DNA binding Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhanc (more detail) 102 NA Homo sapiens

GOA TAX017168 GO:0008276 molecular function protein methyltransferase activity Catalysis of the transfer of a methyl group (CH3-) to a protein. (more detail) 90 NA Homo sapiens

GOA TAX022852 GO:0035383 biological process thioester metabolic process The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' i (more detail) 90 NA Homo sapiens

GOA MEX002413 Genes associated with Kinase Inhibitor Ponatinib Genes associated with Kinase Inhibitor Ponatinib, curated by the Drug Signature Database (DSigDB). (more detail) 90 25990557 Homo sapiens

DSigDB TAX016489 GO:0006637 biological process acyl CoA metabolic process The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the su (more detail) 90 NA Homo sapiens

GOA TAX031077 GO:0098687 cellular component chromosomal region Any subdivision of a chromosome along its length. (more detail) 202 NA Homo sapiens

GOA TAX029693 GO:0071826 biological process ribonucleoprotein complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the forma (more detail) 228 NA Homo sapiens

GOA WIG000586 Pathways in cancer (more detail) 321 NA Homo sapiens

MSigDB TAX014430 GO:0002768 biological process immune response regulating cell surface receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on t (more detail) 384 NA Homo sapiens

GOA WIG000984 Genes involved in Metabolism of RNA (more detail) 313 NA Homo sapiens

MSigDB WIG001470 DNA Repair Mechanism DNA Repair Mechanism (more detail) 105 NA Homo sapiens

Protein Lounge WIG001171 Genes involved in RNA Polymerase II Transcription (more detail) 94 NA Homo sapiens

MSigDB WIG001823 Base excision and single strand break repair Base excision repair (BER) is primarily responsible for removing small, non-helix distorting base le (more detail) 94 NA Homo sapiens

Spike IEI011547 Protein protein interactors of human gene RPL7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL7 (SwissProt ID=P (more detail) 167 17535438 Homo sapiens

I2D IEI005930 Protein protein interactors of human gene HNRNPA2B1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPA2B1 (SwissProt (more detail) 240 17535438 Homo sapiens

I2D FEX012312 The genes express in high level in the celltype glandular cells in the small intestine normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1455 25613900 Homo sapiens

HPA-normProtein TAX025850 GO:0046982 molecular function protein heterodimerization activity Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. (more detail) 419 NA Homo sapiens

GOA TAX020195 GO:0022618 biological process ribonucleoprotein complex assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleo (more detail) 214 NA Homo sapiens

GOA WAG000796 MAPK signaling pathway The mitogen-activated protein kise (MAPK) cascade is a highly conserved module that is involved in v (more detail) 233 NA Homo sapiens

KEGG TAX031707 GO:0140101 molecular function catalytic activity, acting on a tRNA Catalytic activity that acts to modify a tRNA. (more detail) 104 NA Homo sapiens

GOA IEI011574 Protein protein interactors of human gene RPS13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS13 (SwissProt ID= (more detail) 198 17535438 Homo sapiens

I2D TAX014230 GO:0002429 biological process immune response activating cell surface receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on t (more detail) 352 NA Homo sapiens

GOA IEI012592 Protein protein interactors of human gene SMARCAD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCAD1 (SwissProt (more detail) 125 17535438 Homo sapiens

I2D TAX016696 GO:0006952 biological process defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, w (more detail) 1139 NA Homo sapiens

GOA TAX000517 Genes annotated by the GO term GO:0051254. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. (more detail) 119 NA Homo sapiens

MSigDB FAX000289 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif GGGTGGRR which matches annotation for PAX4: paired box gene 4 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif GGGTGGRR (more detail) 1212 NA Homo sapiens

MSigDB TAX035108 GO:2001233 biological process regulation of apoptotic signaling pathway Any process that modulates the frequency, rate or extent of apoptotic signaling pathway. (more detail) 376 NA Homo sapiens

GOA IEI011518 Protein protein interactors of human gene RPL23A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL23A (SwissProt ID (more detail) 204 17535438 Homo sapiens

I2D IEI003408 Protein protein interactors of human gene DDX17 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX17 (SwissProt ID= (more detail) 177 17535438 Homo sapiens

I2D IEI010498 Protein protein interactors of human gene PRKN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRKN (SwissProt ID=O (more detail) 389 17535438 Homo sapiens

I2D GOX001483 Genes regulated by the microRNA hsa miR 124 3p.2 using target scan (more detail) 1244 NA Homo sapiens

TargetScan GOX001492 Genes regulated by the microRNA hsa miR 506 3p using target scan (more detail) 1244 NA Homo sapiens

TargetScan IEI011120 Protein protein interactors of human gene RBX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBX1 (SwissProt ID=P (more detail) 148 17535438 Homo sapiens

I2D MAX002340 Genes constituting the LIT Int network of proteins interacting with breast cancer reference proteins BRCA1, BRCA2, ATM, and CHEK2 [GeneID=672;675;472;11200]; the interactions were manually curated from the literature. Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms (more detail) 96 NA Homo sapiens

MSigDB TAX020811 GO:0031098 biological process stress activated protein kinase signaling cascade A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one o (more detail) 103 NA Homo sapiens

GOA MEX001740 Genes associated with Kinase Inhibitor A 770041 Genes associated with Kinase Inhibitor A-770041, curated by the Drug Signature Database (DSigDB). (more detail) 92 25990557 Homo sapiens

DSigDB FEX002495 Ovarian Crijns09 2394Genes 17PathwayPredictor Table S4.Genes from 17 pathways to be related to survival in 157 advanced stage serous ovarian cance (more detail) 1552 19192944 Homo sapiens

GeneSigDB FEX012739 The diagnosis of Hepatocellular carcinoma, NOS (stage ii) in Liver (TCGA 5C A9VG FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 356 25613900 Homo sapiens

HPA-TCGA FEX014978 The diagnosis of Hepatocellular carcinoma, NOS (stage ii) in Liver (TCGA 2Y A9GY FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 414 25613900 Homo sapiens

HPA-TCGA TAX023920 GO:0042592 biological process homeostatic process Any biological process involved in the maintenance of an internal steady state. (more detail) 1381 NA Homo sapiens

GOA GOX001632 Genes regulated by the microRNA hsa miR 19a 3p using target scan (more detail) 1257 NA Homo sapiens

TargetScan GOX001501 Genes regulated by the microRNA hsa miR 19b 3p using target scan (more detail) 1257 NA Homo sapiens

TargetScan TAX030306 GO:0090068 biological process positive regulation of cell cycle process Any process that increases the rate, frequency or extent of a cellular process that is involved in t (more detail) 264 NA Homo sapiens

GOA TAX024756 GO:0044445 cellular component cytosolic part Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or part (more detail) 270 NA Homo sapiens

GOA TAX014766 GO:0003697 molecular function single stranded DNA binding Interacting selectively and non-covalently with single-stranded DNA. (more detail) 109 NA Homo sapiens

GOA IEI014803 Protein protein interactors of human gene USP7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP7 (SwissProt ID=Q (more detail) 216 17535438 Homo sapiens

I2D MAX000199 Selected genes down regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [GeneID=3265]. Deregulation of Ras pathways results in complex abnormalities of multiple signaling cascades that co (more detail) 329 NA Homo sapiens

MSigDB MAX001163 Housekeeping genes identified as expressed across 19 normal tissues. This study creates a compendium of gene expression in normal human tissues suitable as a reference f (more detail) 369 NA Homo sapiens

MSigDB IEI001046 Protein protein interactors of human gene ATM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATM (SwissProt ID=Q1 (more detail) 157 17535438 Homo sapiens

I2D TAX031124 GO:0098781 biological process ncRNA transcription The transcription of non (protein) coding RNA from a DNA template. (more detail) 87 NA Homo sapiens

GOA TAX018852 GO:0016073 biological process snRNA metabolic process The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular (more detail) 87 NA Homo sapiens

GOA MAX001342 Genes involved in DNA replication, compiled manually by the authors. We have identified a gene-profile signature for human primary malignant melanoma associated with met (more detail) 142 NA Homo sapiens

MSigDB FEX012306 The genes express in high level in the celltype cells in tubules in the kidney normal tissue. Expression profiles for proteins in human tissues based on immunohistochemisty using tissue micro ar (more detail) 1303 25613900 Homo sapiens

HPA-normProtein IEI014682 Protein protein interactors of human gene ULK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ULK2 (SwissProt ID=Q (more detail) 313 17535438 Homo sapiens

I2D WIG000604 Pyrimidine metabolism (more detail) 95 NA Homo sapiens

MSigDB GOX001663 Genes regulated by the microRNA hsa miR 182 5p using target scan (more detail) 1236 NA Homo sapiens

TargetScan IEI015010 Protein protein interactors of human gene WDR5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR5 (SwissProt ID=P (more detail) 154 17535438 Homo sapiens

I2D FEX012859 The diagnosis of Hepatocellular carcinoma, NOS (stage ii) in Liver (TCGA DD AAVU FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 442 25613900 Homo sapiens

HPA-TCGA TAX000521 Genes annotated by the GO term GO:0045893. Any process that activates or increases the frequency, rate or extent of DNA dependent transcription. (more detail) 117 NA Homo sapiens

MSigDB WIG000854 Genes involved in G1/S Transition (more detail) 108 NA Homo sapiens

MSigDB IEI011508 Protein protein interactors of human gene RPL14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL14 (SwissProt ID= (more detail) 193 17535438 Homo sapiens

I2D TAX000107 Genes annotated by the GO term GO:0007049. The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. (more detail) 308 NA Homo sapiens

MSigDB TAX026788 GO:0051091 biological process positive regulation of DNA binding transcription factor activity Any process that activates or increases the frequency, rate or extent of activity of a transcription (more detail) 248 NA Homo sapiens

GOA IEI014541 Protein protein interactors of human gene U2AF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene U2AF2 (SwissProt ID= (more detail) 170 17535438 Homo sapiens

I2D TAX019496 GO:0018210 biological process peptidyl threonine modification The modification of peptidyl-threonine. (more detail) 86 NA Homo sapiens

GOA TAX017565 GO:0009168 biological process purine ribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphat (more detail) 86 NA Homo sapiens

GOA TAX017525 GO:0009127 biological process purine nucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a (more detail) 86 NA Homo sapiens

GOA MEX001604 Genes associated with Kinase Inhibitor BRD K29385665 001 01 1 Genes associated with Kinase Inhibitor BRD-K29385665-001-01-1, curated by the Drug Signature Databas (more detail) 86 25990557 Homo sapiens

DSigDB IEI011509 Protein protein interactors of human gene RPL15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL15 (SwissProt ID= (more detail) 179 17535438 Homo sapiens

I2D TAX028322 GO:0061136 biological process regulation of proteasomal protein catabolic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways res (more detail) 179 NA Homo sapiens

GOA IEI011548 Protein protein interactors of human gene RPL7A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL7A (SwissProt ID= (more detail) 199 17535438 Homo sapiens

I2D IEI010293 Protein protein interactors of human gene PPARG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPARG (SwissProt ID= (more detail) 165 17535438 Homo sapiens

I2D IEI011575 Protein protein interactors of human gene RPS14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS14 (SwissProt ID= (more detail) 183 17535438 Homo sapiens

I2D IEI008640 Protein protein interactors of human gene NCOR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCOR2 (SwissProt ID= (more detail) 116 17535438 Homo sapiens

I2D TAX000051 Genes annotated by the GO term GO:0043285. The chemical reactions and pathways resulting in the breakdown of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. (more detail) 113 NA Homo sapiens

MSigDB IEI011592 Protein protein interactors of human gene RPS27A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS27A (SwissProt ID (more detail) 176 17535438 Homo sapiens

I2D FEX012397 The genes express in the subcellular location of cytosol. Subcellular location of proteins based on immunofluorescently stained cells. The tab-separated file (more detail) 2373 28495876 Homo sapiens

HPA-CellAtlas FEX014964 The diagnosis of Hepatocellular carcinoma, NOS (stage iiib) in Liver (TCGA G3 A7M9 FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 386 25613900 Homo sapiens

HPA-TCGA TAX016510 GO:0006664 biological process glycolipid metabolic process The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined (more detail) 100 NA Homo sapiens

GOA IEI014086 Protein protein interactors of human gene TOP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TOP1 (SwissProt ID=P (more detail) 159 17535438 Homo sapiens

I2D IEI007691 Protein protein interactors of human gene MAPK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPK3 (SwissProt ID= (more detail) 217 17535438 Homo sapiens

I2D IEI014585 Protein protein interactors of human gene UBE2N from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2N (SwissProt ID= (more detail) 191 17535438 Homo sapiens

I2D WAG000382 Aminoacyl tRNA biosynthesis (more detail) 89 NA Homo sapiens

KEGG TAX000552 Genes annotated by the GO term GO:0007243. A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. (more detail) 286 NA Homo sapiens

MSigDB IEI005059 Protein protein interactors of human gene GAPDH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GAPDH (SwissProt ID= (more detail) 284 17535438 Homo sapiens

I2D IEI011613 Protein protein interactors of human gene RPS7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS7 (SwissProt ID=P (more detail) 168 17535438 Homo sapiens

I2D FEX001138 Immune Allen10 2900genes SuppTable 1. LCH CD207 vs Control Skin CD207 - Expression Array Results (LCH CD207/Skin CD207). Lang (more detail) 1704 20220088 Homo sapiens

GeneSigDB FEX017157 The diagnosis of Papillary transitional cell carcinoma (stage iii) in Bladder, NOS (TCGA XF A9ST FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 411 25613900 Homo sapiens

HPA-TCGA IEI005940 Protein protein interactors of human gene HNRNPH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPH1 (SwissProt I (more detail) 227 17535438 Homo sapiens

I2D IEI011552 Protein protein interactors of human gene RPLP0 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPLP0 (SwissProt ID= (more detail) 210 17535438 Homo sapiens

I2D IEI005659 Protein protein interactors of human gene H2AX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AX (SwissProt ID=P (more detail) 231 17535438 Homo sapiens

I2D FEX013210 The diagnosis of Carcinoma, NOS (stage ii) in Bladder, NOS (TCGA ZF AA4N FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 368 25613900 Homo sapiens

HPA-TCGA IEI007607 Protein protein interactors of human gene MAGOH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAGOH (SwissProt ID= (more detail) 199 17535438 Homo sapiens

I2D TAX019097 GO:0016571 biological process histone methylation The modification of histones by addition of methyl groups. (more detail) 84 NA Homo sapiens

GOA TAX020329 GO:0030148 biological process sphingolipid biosynthetic process The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of l (more detail) 84 NA Homo sapiens

GOA FEX012735 The diagnosis of Hepatocellular carcinoma, NOS (not reported) in Liver (TCGA MI A75H FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 427 25613900 Homo sapiens

HPA-TCGA TAX026240 GO:0048598 biological process embryonic morphogenesis The process in which anatomical structures are generated and organized during the embryonic phase. T (more detail) 392 NA Homo sapiens

GOA IEI008956 Protein protein interactors of human gene NOTCH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOTCH1 (SwissProt ID (more detail) 201 17535438 Homo sapiens

I2D TAX023394 GO:0036464 cellular component cytoplasmic ribonucleoprotein granule A ribonucleoprotein granule located in the cytoplasm. (more detail) 192 NA Homo sapiens

GOA TAX016712 GO:0006979 biological process response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 341 NA Homo sapiens

GOA IEI005937 Protein protein interactors of human gene HNRNPD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPD (SwissProt ID (more detail) 257 17535438 Homo sapiens

I2D FEX016527 The diagnosis of Hepatocellular carcinoma, NOS (stage ii) in Liver (TCGA DD A1EL FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 406 25613900 Homo sapiens

HPA-TCGA IEI014571 Protein protein interactors of human gene UBE2E1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2E1 (SwissProt ID (more detail) 125 17535438 Homo sapiens

I2D TAX001426 Genes annotated by the GO term GO:0016757. Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). (more detail) 111 NA Homo sapiens

MSigDB IEI013096 Protein protein interactors of human gene STAU1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAU1 (SwissProt ID= (more detail) 302 17535438 Homo sapiens

I2D TAX016495 GO:0006644 biological process phospholipid metabolic process The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as (more detail) 402 NA Homo sapiens

GOA IEI011513 Protein protein interactors of human gene RPL19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL19 (SwissProt ID= (more detail) 169 17535438 Homo sapiens

I2D MOX005046 Genes associated with Computational Drug Signature staurosporine Genes associated with Computational Drug Signature staurosporine, curated by the Drug Signature Data (more detail) 169 25990557 Homo sapiens

DSigDB IEI004881 Protein protein interactors of human gene FOXO3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXO3 (SwissProt ID= (more detail) 300 17535438 Homo sapiens

I2D IEI011528 Protein protein interactors of human gene RPL31 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL31 (SwissProt ID= (more detail) 178 17535438 Homo sapiens

I2D IEI009945 Protein protein interactors of human gene PIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIN1 (SwissProt ID=Q (more detail) 242 17535438 Homo sapiens

I2D IEI012989 Protein protein interactors of human gene SRRM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRRM1 (SwissProt ID= (more detail) 135 17535438 Homo sapiens

I2D MEX001840 Genes associated with Kinase Inhibitor SB 218078 Genes associated with Kinase Inhibitor SB 218078, curated by the Drug Signature Database (DSigDB). (more detail) 83 25990557 Homo sapiens

DSigDB TAX021379 GO:0032200 biological process telomere organization A process that is carried out at the cellular level which results in the assembly, arrangement of co (more detail) 83 NA Homo sapiens

GOA IEI011587 Protein protein interactors of human gene RPS24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS24 (SwissProt ID= (more detail) 221 17535438 Homo sapiens

I2D FEX018425 The diagnosis of Hepatocellular carcinoma, NOS (stage i) in Liver (TCGA FV A4ZQ FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 353 25613900 Homo sapiens

HPA-TCGA TAX000076 Genes annotated by the GO term GO:0044249. The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. (more detail) 305 NA Homo sapiens

MSigDB TAX032978 GO:1903509 biological process liposaccharide metabolic process The chemical reactions and pathways involving liposaccharide. (more detail) 101 NA Homo sapiens

GOA FAX000272 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif GCCATNTTG which matches annotation for YY1: YY1 transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif GCCATNTT (more detail) 399 NA Homo sapiens

MSigDB MAX003154 The 'core ESC like gene module': genes coordinately up regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC like module. Self-renewal is a hallmark of stem cells and cancer, but existence of a shared stemness program rema (more detail) 324 NA Homo sapiens

MSigDB IEI012092 Protein protein interactors of human gene SFPQ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SFPQ (SwissProt ID=P (more detail) 197 17535438 Homo sapiens

I2D FEX012798 The diagnosis of Hepatocellular carcinoma, NOS (stage i) in Liver (TCGA DD AACW FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 335 25613900 Homo sapiens

HPA-TCGA IEI003068 Protein protein interactors of human gene CSNK2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSNK2B (SwissProt ID (more detail) 259 17535438 Homo sapiens

I2D TAX032328 GO:1901991 biological process negative regulation of mitotic cell cycle phase transition Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phas (more detail) 156 NA Homo sapiens

GOA IEI008797 Protein protein interactors of human gene NFKBIA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFKBIA (SwissProt ID (more detail) 163 17535438 Homo sapiens

I2D TAX015204 GO:0004527 molecular function exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues f (more detail) 82 NA Homo sapiens

GOA MEX002344 Genes associated with Kinase Inhibitor staurosporine Genes associated with Kinase Inhibitor staurosporine, curated by the Drug Signature Database (DSigDB (more detail) 82 25990557 Homo sapiens

DSigDB TAX013464 GO:0000723 biological process telomere maintenance Any process that contributes to the maintenance of proper telomeric length and structure by affectin (more detail) 82 NA Homo sapiens

GOA TAX016245 GO:0006304 biological process DNA modification The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its propert (more detail) 82 NA Homo sapiens

GOA IEI010930 Protein protein interactors of human gene RACK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RACK1 (SwissProt ID= (more detail) 224 17535438 Homo sapiens

I2D IEI008410 Protein protein interactors of human gene MYBBP1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYBBP1A (SwissProt I (more detail) 126 17535438 Homo sapiens

I2D IEI010533 Protein protein interactors of human gene PRPF19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRPF19 (SwissProt ID (more detail) 146 17535438 Homo sapiens

I2D IEI012084 Protein protein interactors of human gene SF3B3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SF3B3 (SwissProt ID= (more detail) 183 17535438 Homo sapiens

I2D TAX034561 GO:2000257 biological process regulation of protein activation cascade Any process that modulates the frequency, rate or extent of protein activation cascade. (more detail) 112 NA Homo sapiens

GOA IEI011545 Protein protein interactors of human gene RPL5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL5 (SwissProt ID=P (more detail) 215 17535438 Homo sapiens

I2D IEI002237 Protein protein interactors of human gene CDK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK1 (SwissProt ID=P (more detail) 252 17535438 Homo sapiens

I2D IEI000924 Protein protein interactors of human gene ARRB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARRB2 (SwissProt ID= (more detail) 343 17535438 Homo sapiens

I2D TAX024943 GO:0045088 biological process regulation of innate immune response Any process that modulates the frequency, rate or extent of the innate immune response, the organism (more detail) 356 NA Homo sapiens

GOA IEI011504 Protein protein interactors of human gene RPL12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL12 (SwissProt ID= (more detail) 171 17535438 Homo sapiens

I2D TAX016560 GO:0006733 biological process oxidoreduction coenzyme metabolic process The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme (more detail) 125 NA Homo sapiens

GOA TAX017391 GO:0008652 biological process cellular amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids contain (more detail) 81 NA Homo sapiens

GOA TAX017593 GO:0009201 biological process ribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a c (more detail) 81 NA Homo sapiens

GOA TAX017530 GO:0009132 biological process nucleoside diphosphate metabolic process The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a n (more detail) 81 NA Homo sapiens

GOA MEX002399 Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 81 25990557 Homo sapiens

DSigDB MEX002053 Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 81 25990557 Homo sapiens

DSigDB TAX013466 GO:0000725 biological process recombinational repair A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material be (more detail) 81 NA Homo sapiens

GOA MOX001340 Genes associated with Computational Drug Signature CUPRIC OXIDE Genes associated with Computational Drug Signature CUPRIC OXIDE, curated by the Drug Signature Datab (more detail) 380 25990557 Homo sapiens

DSigDB IEI011459 Protein protein interactors of human gene RNPS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNPS1 (SwissProt ID= (more detail) 164 17535438 Homo sapiens

I2D TAX001069 Genes annotated by the GO term GO:0030554. Interacting selectively with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate. (more detail) 164 NA Homo sapiens

MSigDB TAX017689 GO:0009416 biological process response to light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 283 NA Homo sapiens

GOA WIG001988 Cytoplasmic Ribosomal Proteins Cytoplasmic Ribosomal Proteins (more detail) 89 NA Homo sapiens

WikiPathway TAX028655 GO:0062012 biological process regulation of small molecule metabolic process Any process that modulates the rate, frequency or extent of a small molecule metabolic process. (more detail) 331 NA Homo sapiens

GOA TAX020517 GO:0030449 biological process regulation of complement activation Any process that modulates the frequency, rate or extent of complement activation. (more detail) 111 NA Homo sapiens

GOA WIG001001 Genes involved in mRNA Processing (more detail) 152 NA Homo sapiens

MSigDB IEI007688 Protein protein interactors of human gene MAPK14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPK14 (SwissProt ID (more detail) 228 17535438 Homo sapiens

I2D TAX030550 GO:0090502 biological process RNA phosphodiester bond hydrolysis, endonucleolytic The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds (more detail) 80 NA Homo sapiens

GOA TAX013465 GO:0000724 biological process double strand break repair via homologous recombination The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired u (more detail) 80 NA Homo sapiens

GOA MEX001415 Genes associated with Kinase Inhibitor Kinome 3629 Genes associated with Kinase Inhibitor Kinome_3629, curated by the Drug Signature Database (DSigDB). (more detail) 80 25990557 Homo sapiens

DSigDB TAX017686 GO:0009411 biological process response to UV Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 134 NA Homo sapiens

GOA FAX000470 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif TTTSSCGC which matches annotation for E2F1: E2F transcription factor 1
TFDP2: transcription factor Dp 2 (E2F dimerization partner 2) Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTSSCGC (more detail) 215 NA Homo sapiens

MSigDB FAX000480 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif TTTSGCGC. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif TTTSGCGC. Mo (more detail) 215 NA Homo sapiens

MSigDB FAX000469 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F1: E2F transcription factor 1
TFDP1: transcription factor Dp 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTCSCGC (more detail) 215 NA Homo sapiens

MSigDB FAX000478 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F4: E2F transcription factor 4, p107/p130 binding
TFDP2: transcription factor Dp 2 (E2F dimerization partner 2) Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTCSCGC (more detail) 215 NA Homo sapiens

MSigDB WIG000612 Ribosome (more detail) 88 NA Homo sapiens

MSigDB TAX001043 Genes annotated by the GO term GO:0005667. Any complex, distinct from RNA polymerase, including one or more polypeptides capable of binding DNA at promoters or at cis acting regulatory sequences, and regulating transcription. (more detail) 88 NA Homo sapiens

MSigDB MEX000761 Genes associated with Approved Drug gefitinib Genes associated with Approved Drug gefitinib, curated by the Drug Signature Database (DSigDB). (more detail) 88 25990557 Homo sapiens

DSigDB TAX001070 Genes annotated by the GO term GO:0032559. Interacting selectively with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. (more detail) 158 NA Homo sapiens

MSigDB TAX019641 GO:0019216 biological process regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 367 NA Homo sapiens

GOA TAX016720 GO:0006996 biological process organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of co (more detail) 2140 NA Homo sapiens

GOA IEI012993 Protein protein interactors of human gene SRSF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF1 (SwissProt ID= (more detail) 178 17535438 Homo sapiens

I2D WIG000976 Genes involved in Metabolism of carbohydrates (more detail) 235 NA Homo sapiens

MSigDB IEI014608 Protein protein interactors of human gene UBL4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBL4A (SwissProt ID= (more detail) 271 17535438 Homo sapiens

I2D TAX017875 GO:0010212 biological process response to ionizing radiation Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 148 NA Homo sapiens

GOA WIG001247 Genes involved in Synthesis of DNA (more detail) 91 NA Homo sapiens

MSigDB TAX000739 Genes annotated by the GO term GO:0008380. The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. (more detail) 91 NA Homo sapiens

MSigDB IEI009420 Protein protein interactors of human gene PABPC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PABPC1 (SwissProt ID (more detail) 239 17535438 Homo sapiens

I2D TAX016317 GO:0006417 biological process regulation of translation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 325 NA Homo sapiens

GOA TAX029031 GO:0070613 biological process regulation of protein processing Any process that modulates the frequency, rate or extent of protein processing, any protein maturati (more detail) 173 NA Homo sapiens

GOA IEI002306 Protein protein interactors of human gene CEBPB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CEBPB (SwissProt ID= (more detail) 138 17535438 Homo sapiens

I2D IEI001819 Protein protein interactors of human gene CASP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASP3 (SwissProt ID= (more detail) 197 17535438 Homo sapiens

I2D TAX015433 GO:0004843 molecular function thiol dependent ubiquitin specific protease activity Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ub (more detail) 79 NA Homo sapiens

GOA MOX013004 Genes associated with Computational Drug Signature hesperadin Genes associated with Computational Drug Signature hesperadin, curated by the Drug Signature Databas (more detail) 79 25990557 Homo sapiens

DSigDB TAX019462 GO:0018107 biological process peptidyl threonine phosphorylation The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. (more detail) 79 NA Homo sapiens

GOA TAX019445 GO:0018022 biological process peptidyl lysine methylation The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative. (more detail) 79 NA Homo sapiens

GOA TAX000024 Genes annotated by the GO term GO:0006519. The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids. (more detail) 94 NA Homo sapiens

MSigDB TAX016498 GO:0006650 biological process glycerophospholipid metabolic process The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophospha (more detail) 332 NA Homo sapiens

GOA MEX002312 Genes associated with Kinase Inhibitor Tozasertib Genes associated with Kinase Inhibitor Tozasertib, curated by the Drug Signature Database (DSigDB). (more detail) 87 25990557 Homo sapiens

DSigDB TAX032889 GO:1903317 biological process regulation of protein maturation Any process that modulates the frequency, rate or extent of protein maturation. (more detail) 175 NA Homo sapiens

GOA FEX018427 The diagnosis of Hepatocellular carcinoma, NOS (stage iiia) in Liver (TCGA CC A7IE FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 311 25613900 Homo sapiens

HPA-TCGA TAX026898 GO:0051251 biological process positive regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of lymphocyte activation. (more detail) 309 NA Homo sapiens

GOA TAX024040 GO:0042826 molecular function histone deacetylase binding Interacting selectively and non-covalently with the enzyme histone deacetylase. (more detail) 106 NA Homo sapiens

GOA IEI011586 Protein protein interactors of human gene RPS23 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS23 (SwissProt ID= (more detail) 188 17535438 Homo sapiens

I2D MAX000433 Genes up regulated 9 h after induction of HoxA5 [GeneID=3205] expression in a breast cancer cell line. The homeobox gene HOXA5 encodes a transcription factor that has been shown to play important roles i (more detail) 203 NA Homo sapiens

MSigDB WAG000290 Eukaryotic Translation Termination (more detail) 83 NA Homo sapiens

Reactome TAX000182 Genes annotated by the GO term GO:0006260. The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. (more detail) 100 NA Homo sapiens

MSigDB IEI007836 Protein protein interactors of human gene MED1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED1 (SwissProt ID=Q (more detail) 100 17535438 Homo sapiens

I2D IEI007855 Protein protein interactors of human gene MED26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED26 (SwissProt ID= (more detail) 100 17535438 Homo sapiens

I2D TAX016227 GO:0006282 biological process regulation of DNA repair Any process that modulates the frequency, rate or extent of DNA repair. (more detail) 103 NA Homo sapiens

GOA FOX000135 Neighborhood of FBL Neighborhood of FBL fibrillarin in the GNF2 expression compendium (more detail) 140 NA Homo sapiens

MSigDB MAX003401 Genes transiently induced only by the first pulse of EGF [GeneID=1950] in 184A1 cells (mammary epithelium). Normal cells require continuous exposure to growth factors in order to cross a restriction point and (more detail) 1605 NA Homo sapiens

MSigDB IEI003160 Protein protein interactors of human gene CUL4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUL4A (SwissProt ID= (more detail) 250 17535438 Homo sapiens

I2D WIG000743 Genes involved in Cell Cycle (more detail) 352 NA Homo sapiens

MSigDB TAX025244 GO:0045732 biological process positive regulation of protein catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 209 NA Homo sapiens

GOA TAX034455 GO:2000058 biological process regulation of ubiquitin dependent protein catabolic process Any process that modulates the frequency, rate or extent of ubiquitin-dependent protein catabolic pr (more detail) 154 NA Homo sapiens

GOA IEI000361 Protein protein interactors of human gene AGO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AGO1 (SwissProt ID=Q (more detail) 211 17535438 Homo sapiens

I2D WEX000020 DNA Damage Repair The genes related to dna damage repair (cell function) in tumor using next-generation sequencer (NGS (more detail) 90 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas FEX015036 The diagnosis of Hepatocellular carcinoma, NOS (stage i) in Liver (TCGA DD AACA FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 348 25613900 Homo sapiens

HPA-TCGA TAX016918 GO:0007389 biological process pattern specification process Any developmental process that results in the creation of defined areas or spaces within an organism (more detail) 348 NA Homo sapiens

GOA TAX026518 GO:0050684 biological process regulation of mRNA processing Any process that modulates the frequency, rate or extent of mRNA processing, those processes involve (more detail) 114 NA Homo sapiens

GOA IEI005549 Protein protein interactors of human gene GSK3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GSK3B (SwissProt ID= (more detail) 342 17535438 Homo sapiens

I2D IEI014881 Protein protein interactors of human gene VIM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VIM (SwissProt ID=P0 (more detail) 306 17535438 Homo sapiens

I2D IEI008721 Protein protein interactors of human gene NEDD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEDD4 (SwissProt ID= (more detail) 277 17535438 Homo sapiens

I2D TAX016272 GO:0006354 biological process DNA templated transcription, elongation The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-depe (more detail) 78 NA Homo sapiens

GOA TAX022627 GO:0034708 cellular component methyltransferase complex A protein complex that possesses methyltransferase activity. (more detail) 93 NA Homo sapiens

GOA IEI008948 Protein protein interactors of human gene NOP58 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOP58 (SwissProt ID= (more detail) 93 17535438 Homo sapiens

I2D TAX017058 GO:0008094 molecular function DNA dependent ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of singl (more detail) 86 NA Homo sapiens

GOA WIG000372 MAPKinase Signaling Pathway The ever evolving mitogen-activated protein kinase (MAP kinase) pathways consist of four major group (more detail) 86 NA Homo sapiens

MSigDB TAX001090 Genes annotated by the GO term GO:0005524. Interacting selectively with ATP, adenosine 5' triphosphate, a universally important coenzyme and enzyme regulator. (more detail) 151 NA Homo sapiens

MSigDB TAX014354 GO:0002673 biological process regulation of acute inflammatory response Any process that modulates the frequency, rate, or extent of an acute inflammatory response. (more detail) 151 NA Homo sapiens

GOA TAX024349 GO:0043406 biological process positive regulation of MAP kinase activity Any process that activates or increases the frequency, rate or extent of MAP kinase activity. (more detail) 263 NA Homo sapiens

GOA MAX000145 Breast cancer compendium: 100 transcription regulators showing most correlated expression with the 9 'embryonic stem cell' transcription factors that are preferentially and coordinately overexpressed in the high grade, ER negative breast cancer tumors. Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear, howev (more detail) 99 NA Homo sapiens

MSigDB IEI011537 Protein protein interactors of human gene RPL37A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL37A (SwissProt ID (more detail) 129 17535438 Homo sapiens

I2D IEI013495 Protein protein interactors of human gene TCF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCF3 (SwissProt ID=P (more detail) 160 17535438 Homo sapiens

I2D FAX000475 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif TTTSGCGS which matches annotation for E2F1: E2F transcription factor 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTSGCGS (more detail) 212 NA Homo sapiens

MSigDB TAX023026 GO:0035690 biological process cellular response to drug Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 286 NA Homo sapiens

GOA WIG001834 The GJB2 Interactions in the Ear GJB2, encoding connexin 26 protein, is involved in up to 50% of non-syndromic hearing loss in many w (more detail) 141 NA Homo sapiens

Spike TAX023491 GO:0038095 biological process Fc epsilon receptor signaling pathway A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) t (more detail) 121 NA Homo sapiens

GOA IEI011514 Protein protein interactors of human gene RPL21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL21 (SwissProt ID= (more detail) 171 17535438 Homo sapiens

I2D TAX026769 GO:0051053 biological process negative regulation of DNA metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 131 NA Homo sapiens

GOA FEX012923 The diagnosis of Hepatocellular carcinoma, NOS (stage i) in Liver (TCGA EP A2KB FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 335 25613900 Homo sapiens

HPA-TCGA FEX020471 The diagnosis of Adenocarcinoma, NOS (stage iiib) in Body of stomach (TCGA BR 7723 FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 297 25613900 Homo sapiens

HPA-TCGA TAX018844 GO:0016054 biological process organic acid catabolic process The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound (more detail) 236 NA Homo sapiens

GOA TAX025553 GO:0046395 biological process carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid (more detail) 236 NA Homo sapiens

GOA TAX023422 GO:0036503 biological process ERAD pathway The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degrada (more detail) 77 NA Homo sapiens

GOA WIG001717 Ubiquitin Proteasome Dependent Proteolysis Ubiquitin-Proteasome Dependent Proteolysis (more detail) 77 NA Homo sapiens

Protein Lounge MOX003622 Genes associated with Computational Drug Signature N Acetyl L cysteine Genes associated with Computational Drug Signature N-Acetyl-L-cysteine, curated by the Drug Signatur (more detail) 312 25990557 Homo sapiens

DSigDB IEI004853 Protein protein interactors of human gene FOS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOS (SwissProt ID=P0 (more detail) 209 17535438 Homo sapiens

I2D TAX032046 GO:1901214 biological process regulation of neuron death Any process that modulates the frequency, rate or extent of neuron death. (more detail) 285 NA Homo sapiens

GOA TAX032257 GO:1901796 biological process regulation of signal transduction by p53 class mediator Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediato (more detail) 128 NA Homo sapiens

GOA MAX002265 Genes down regulated in BJAB cells (B lymphoma) after glutamine [PubChem=738] deprivation. RAFT1/FRAP/mTOR is a key regulator of cell growth and division and the mammalian target of rapamycin (more detail) 325 NA Homo sapiens

MSigDB TAX021837 GO:0032879 biological process regulation of localization Any process that modulates the frequency, rate or extent of any process in which a cell, a substance (more detail) 2579 NA Homo sapiens

GOA WAG001152 Viral mRNA Translation (more detail) 81 NA Homo sapiens

Reactome FEX015110 The diagnosis of Seminoma, NOS (is) in Testis, NOS (TCGA XE A8H5 FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 323 25613900 Homo sapiens

HPA-TCGA FAX000477 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F4: E2F transcription factor 4, p107/p130 binding
TFDP1: transcription factor Dp 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTSGCGC (more detail) 217 NA Homo sapiens

MSigDB FOX000841 Genes in the cancer module 83 (more detail) 302 NA Homo sapiens

MSigDB WIG000836 Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism (more detail) 163 NA Homo sapiens

MSigDB IEI012695 Protein protein interactors of human gene SNRPD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRPD1 (SwissProt ID (more detail) 185 17535438 Homo sapiens

I2D TAX014781 GO:0003729 molecular function mRNA binding Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule betwe (more detail) 202 NA Homo sapiens

GOA IEI011550 Protein protein interactors of human gene RPL8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL8 (SwissProt ID=P (more detail) 174 17535438 Homo sapiens

I2D TAX024385 GO:0043484 biological process regulation of RNA splicing Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing se (more detail) 117 NA Homo sapiens

GOA IEI006280 Protein protein interactors of human gene IKBKB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IKBKB (SwissProt ID= (more detail) 189 17535438 Homo sapiens

I2D IEI014681 Protein protein interactors of human gene ULK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ULK1 (SwissProt ID=O (more detail) 337 17535438 Homo sapiens

I2D TAX017543 GO:0009145 biological process purine nucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a (more detail) 76 NA Homo sapiens

GOA TAX016518 GO:0006672 biological process ceramide metabolic process The chemical reactions and pathways involving ceramides, any N-acylated sphingoid. (more detail) 76 NA Homo sapiens

GOA TAX016372 GO:0006497 biological process protein lipidation The covalent attachment of lipid groups to an amino acid in a protein. (more detail) 76 NA Homo sapiens

GOA PEX002586 Pkinase Tyr: Protein tyrosine kinase (more detail) 76 NA Homo sapiens

Pfam TAX016303 GO:0006400 biological process tRNA modification The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule (more detail) 76 NA Homo sapiens

GOA IEI003413 Protein protein interactors of human gene DDX21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX21 (SwissProt ID= (more detail) 167 17535438 Homo sapiens

I2D WIG001611 p53 Signaling p53 Signaling (more detail) 84 NA Homo sapiens

Protein Lounge TAX000088 Genes annotated by the GO term GO:0044265. The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells. (more detail) 100 NA Homo sapiens

MSigDB TAX019004 GO:0016410 molecular function N acyltransferase activity Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule. (more detail) 97 NA Homo sapiens

GOA IEI003989 Protein protein interactors of human gene EFTUD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFTUD2 (SwissProt ID (more detail) 153 17535438 Homo sapiens

I2D TAX024345 GO:0043401 biological process steroid hormone mediated signaling pathway A series of molecular signals mediated by a steroid hormone binding to a receptor. (more detail) 129 NA Homo sapiens

GOA TAX019232 GO:0016811 molecular function hydrolase activity, acting on carbon nitrogen (but not peptide) bonds, in linear amides Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide. (more detail) 87 NA Homo sapiens

GOA TAX015034 GO:0004197 molecular function cysteine type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism i (more detail) 87 NA Homo sapiens

GOA IEI011512 Protein protein interactors of human gene RPL18A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL18A (SwissProt ID (more detail) 148 17535438 Homo sapiens

I2D TAX023811 GO:0042393 molecular function histone binding Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins (more detail) 175 NA Homo sapiens

GOA IEI005939 Protein protein interactors of human gene HNRNPF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPF (SwissProt ID (more detail) 211 17535438 Homo sapiens

I2D IEI012577 Protein protein interactors of human gene SMAD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMAD1 (SwissProt ID= (more detail) 211 17535438 Homo sapiens

I2D WEX000026 Epigenetic Modification The genes related to epigenetic modification (cell function) in tumor using next-generation sequence (more detail) 166 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI014539 Protein protein interactors of human gene U2AF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene U2AF1 (SwissProt ID= (more detail) 121 17535438 Homo sapiens

I2D IEI011527 Protein protein interactors of human gene RPL30 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL30 (SwissProt ID= (more detail) 143 17535438 Homo sapiens

I2D IEI011601 Protein protein interactors of human gene RPS5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS5 (SwissProt ID=P (more detail) 150 17535438 Homo sapiens

I2D TAX013241 GO:0000075 biological process cell cycle checkpoint A cell cycle process that controls cell cycle progression by monitoring the integrity of specific ce (more detail) 126 NA Homo sapiens

GOA TAX017598 GO:0009206 biological process purine ribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate (more detail) 75 NA Homo sapiens

GOA TAX020833 GO:0031124 biological process mRNA 3' end processing Any process involved in forming the mature 3' end of an mRNA molecule. (more detail) 75 NA Homo sapiens

GOA TAX016284 GO:0006368 biological process transcription elongation from RNA polymerase II promoter The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA pol (more detail) 75 NA Homo sapiens

GOA WAG000504 Peptide chain elongation (more detail) 83 NA Homo sapiens

Reactome MEX002400 Genes associated with Kinase Inhibitor Palbociclib Genes associated with Kinase Inhibitor Palbociclib, curated by the Drug Signature Database (DSigDB). (more detail) 83 25990557 Homo sapiens

DSigDB MEX001819 Genes associated with Kinase Inhibitor Palbociclib Genes associated with Kinase Inhibitor Palbociclib, curated by the Drug Signature Database (DSigDB). (more detail) 83 25990557 Homo sapiens

DSigDB IEI010639 Protein protein interactors of human gene PSMC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMC1 (SwissProt ID= (more detail) 113 17535438 Homo sapiens

I2D IEI013569 Protein protein interactors of human gene TERF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TERF2 (SwissProt ID= (more detail) 251 17535438 Homo sapiens

I2D IEI006905 Protein protein interactors of human gene KLHDC10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHDC10 (SwissProt I (more detail) 249 17535438 Homo sapiens

I2D IEI003421 Protein protein interactors of human gene DDX3X from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX3X (SwissProt ID= (more detail) 239 17535438 Homo sapiens

I2D IEI011584 Protein protein interactors of human gene RPS20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS20 (SwissProt ID= (more detail) 181 17535438 Homo sapiens

I2D IEI002305 Protein protein interactors of human gene CEBPA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CEBPA (SwissProt ID= (more detail) 123 17535438 Homo sapiens

I2D TAX015591 GO:0005102 molecular function signaling receptor binding Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a (more detail) 1572 NA Homo sapiens

GOA TAX001216 Genes annotated by the GO term GO:0043167. Interacting selectively with ions, charged atoms or groups of atoms. (more detail) 266 NA Homo sapiens

MSigDB FEX020398 The diagnosis of Hepatocellular carcinoma, NOS (stage iiia) in Liver (TCGA ED A8O5 FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 323 25613900 Homo sapiens

HPA-TCGA IEI008947 Protein protein interactors of human gene NOP56 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOP56 (SwissProt ID= (more detail) 149 17535438 Homo sapiens

I2D TAX014516 GO:0002920 biological process regulation of humoral immune response Any process that modulates the frequency, rate, or extent of a humoral immune response. (more detail) 130 NA Homo sapiens

GOA IEI012683 Protein protein interactors of human gene SNRNP200 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRNP200 (SwissProt (more detail) 158 17535438 Homo sapiens

I2D FOX000344 Neighborhood of NPM1 Neighborhood of NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) in the MORF expression (more detail) 158 NA Homo sapiens

MSigDB TAX001419 Genes annotated by the GO term GO:0003714. The function of a transcription cofactor that represses transcription from a RNA polymerase II promoter; does not bind DNA itself. (more detail) 92 NA Homo sapiens

MSigDB MOX002511 Genes associated with Computational Drug Signature MG 132 Genes associated with Computational Drug Signature MG-132, curated by the Drug Signature Database (D (more detail) 169 25990557 Homo sapiens

DSigDB TAX013572 GO:0000980 molecular function RNA polymerase II distal enhancer sequence specific DNA binding Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mam (more detail) 82 NA Homo sapiens

GOA MEX001742 Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 78 25990557 Homo sapiens

DSigDB FOX000436 Genes in the cancer module 107 (more detail) 78 NA Homo sapiens

MSigDB IEI011519 Protein protein interactors of human gene RPL24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL24 (SwissProt ID= (more detail) 186 17535438 Homo sapiens

I2D IEI009888 Protein protein interactors of human gene PIAS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIAS1 (SwissProt ID= (more detail) 122 17535438 Homo sapiens

I2D FEX000773 Breast Wood10 416genes Supplementary Table 3B: All significantly altered genes related to cell cycle (by ontology analysis) (more detail) 290 20103679 Homo sapiens

GeneSigDB IEI010654 Protein protein interactors of human gene PSMD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD4 (SwissProt ID= (more detail) 146 17535438 Homo sapiens

I2D IEI005933 Protein protein interactors of human gene HNRNPC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPC (SwissProt ID (more detail) 223 17535438 Homo sapiens

I2D IEI012633 Protein protein interactors of human gene SMN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMN1 (SwissProt ID=Q (more detail) 225 17535438 Homo sapiens

I2D MOX001184 Genes associated with Computational Drug Signature 2 Nonenal, 4 hydroxy , (2E,4R) Genes associated with Computational Drug Signature 2-Nonenal, 4-hydroxy-, (2E,4R)-, curated by the D (more detail) 270 25990557 Homo sapiens

DSigDB IEI005670 Protein protein interactors of human gene H2BC21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2BC21 (SwissProt ID (more detail) 159 17535438 Homo sapiens

I2D IEI011616 Protein protein interactors of human gene RPSA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPSA (SwissProt ID=P (more detail) 170 17535438 Homo sapiens

I2D TAX031098 GO:0098732 biological process macromolecule deacylation The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, fro (more detail) 73 NA Homo sapiens

GOA TAX016228 GO:0006283 biological process transcription coupled nucleotide excision repair The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the ac (more detail) 73 NA Homo sapiens

GOA TAX030036 GO:0072525 biological process pyridine containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i. (more detail) 73 NA Homo sapiens

GOA IEI010219 Protein protein interactors of human gene POLR2C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2C (SwissProt ID (more detail) 97 17535438 Homo sapiens

I2D FEX020407 The diagnosis of Papillary serous cystadenocarcinoma (not reported) in Ovary (TCGA 5X AA5U FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 258 25613900 Homo sapiens

HPA-TCGA IEI007800 Protein protein interactors of human gene MCM7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCM7 (SwissProt ID=P (more detail) 254 17535438 Homo sapiens

I2D FAX000484 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F
TFDP1: transcription factor Dp 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTSGCGS (more detail) 214 NA Homo sapiens

MSigDB IEI011526 Protein protein interactors of human gene RPL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL3 (SwissProt ID=P (more detail) 189 17535438 Homo sapiens

I2D IEI005947 Protein protein interactors of human gene HNRNPR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPR (SwissProt ID (more detail) 220 17535438 Homo sapiens

I2D FAX000471 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif NKTSSCGC which matches annotation for E2F1: E2F transcription factor 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif NKTSSCGC (more detail) 224 NA Homo sapiens

MSigDB FEX018974 The diagnosis of Squamous cell carcinoma, NOS (stage iii) in Lower lobe, lung (TCGA O2 A52S FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 300 25613900 Homo sapiens

HPA-TCGA TAX026498 GO:0050662 molecular function coenzyme binding Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofact (more detail) 275 NA Homo sapiens

GOA MAX000601 Genes down regulated in NHEK cells (normal keratinocytes) by UV B irradiation. To gain insight into the transformation of epidermal cells into squamous carcinoma cells (SCC), we c (more detail) 296 NA Homo sapiens

MSigDB TAX000357 Genes annotated by the GO term GO:0016071. The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. (more detail) 84 NA Homo sapiens

MSigDB TAX001227 Genes annotated by the GO term GO:0016874. Catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. (more detail) 84 NA Homo sapiens

MSigDB TAX027764 GO:0060249 biological process anatomical structure homeostasis A homeostatic process involved in the maintenance of an internal steady state within a defined anato (more detail) 267 NA Homo sapiens

GOA MOX003226 Genes associated with Computational Drug Signature 1,9 Pyrazoloanthrone Genes associated with Computational Drug Signature 1,9-Pyrazoloanthrone, curated by the Drug Signatu (more detail) 180 25990557 Homo sapiens

DSigDB IEI005735 Protein protein interactors of human gene HCFC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HCFC1 (SwissProt ID= (more detail) 102 17535438 Homo sapiens

I2D TAX022770 GO:0035239 biological process tube morphogenesis The process in which the anatomical structures of a tube are generated and organized. Epithelial and (more detail) 261 NA Homo sapiens

GOA MOX003789 Genes associated with Computational Drug Signature Capsaicin Genes associated with Computational Drug Signature Capsaicin, curated by the Drug Signature Database (more detail) 205 25990557 Homo sapiens

DSigDB IEI012079 Protein protein interactors of human gene SF3A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SF3A1 (SwissProt ID= (more detail) 142 17535438 Homo sapiens

I2D IEI001489 Protein protein interactors of human gene BTRC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BTRC (SwissProt ID=Q (more detail) 186 17535438 Homo sapiens

I2D IEI007667 Protein protein interactors of human gene MAP3K7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP3K7 (SwissProt ID (more detail) 151 17535438 Homo sapiens

I2D IEI012689 Protein protein interactors of human gene SNRNP70 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRNP70 (SwissProt I (more detail) 151 17535438 Homo sapiens

I2D TAX026990 GO:0051403 biological process stress activated MAPK cascade A series of molecular signals in which a stress-activated MAP kinase cascade relays one or more of t (more detail) 72 NA Homo sapiens

GOA TAX023750 GO:0042278 biological process purine nucleoside metabolic process The chemical reactions and pathways involving one of a family of organic molecules consisting of a p (more detail) 72 NA Homo sapiens

GOA TAX022970 GO:0035601 biological process protein deacylation The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, fro (more detail) 72 NA Homo sapiens

GOA TAX001400 Genes annotated by the GO term GO:0003735. The action of a molecule that contributes to the structural integrity of the ribosome. (more detail) 80 NA Homo sapiens

MSigDB MEX001982 Genes associated with Kinase Inhibitor Aurora A Inhibitor I Genes associated with Kinase Inhibitor Aurora A Inhibitor I, curated by the Drug Signature Database (more detail) 80 25990557 Homo sapiens

DSigDB TAX014537 GO:0003002 biological process regionalization The pattern specification process that results in the subdivision of an axis or axes in space to def (more detail) 221 NA Homo sapiens

GOA IEI010652 Protein protein interactors of human gene PSMD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD2 (SwissProt ID= (more detail) 223 17535438 Homo sapiens

I2D FEX016927 The diagnosis of Seminoma, NOS (stage iib) in Testis, NOS (TCGA 2G AAFH FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 297 25613900 Homo sapiens

HPA-TCGA IEI004344 Protein protein interactors of human gene EWSR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EWSR1 (SwissProt ID= (more detail) 300 17535438 Homo sapiens

I2D MOX002469 Genes associated with Computational Drug Signature Fulvestrant Genes associated with Computational Drug Signature Fulvestrant, curated by the Drug Signature Databa (more detail) 300 25990557 Homo sapiens

DSigDB IEI003535 Protein protein interactors of human gene DHX15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHX15 (SwissProt ID= (more detail) 183 17535438 Homo sapiens

I2D FAX000468 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F1: E2F transcription factor 1
TFDP1: transcription factor Dp 1
RB1: retinoblastoma 1 (including osteosarcoma) Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTSGCGC (more detail) 212 NA Homo sapiens

MSigDB IEI011588 Protein protein interactors of human gene RPS25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS25 (SwissProt ID= (more detail) 150 17535438 Homo sapiens

I2D IEI008941 Protein protein interactors of human gene NONO from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NONO (SwissProt ID=Q (more detail) 187 17535438 Homo sapiens

I2D IEI002263 Protein protein interactors of human gene CDK8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK8 (SwissProt ID=P (more detail) 95 17535438 Homo sapiens

I2D IEI011585 Protein protein interactors of human gene RPS21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS21 (SwissProt ID= (more detail) 124 17535438 Homo sapiens

I2D IEI006631 Protein protein interactors of human gene KAT2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KAT2A (SwissProt ID= (more detail) 124 17535438 Homo sapiens

I2D IEI015005 Protein protein interactors of human gene WDR45 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR45 (SwissProt ID= (more detail) 288 17535438 Homo sapiens

I2D WIG001145 Genes involved in Regulation of mitotic cell cycle (more detail) 79 NA Homo sapiens

MSigDB TAX015344 GO:0004722 molecular function protein serine/threonine phosphatase activity Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein (more detail) 71 NA Homo sapiens

GOA TAX013666 GO:0001510 biological process RNA methylation Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonu (more detail) 71 NA Homo sapiens

GOA TAX024763 GO:0044452 cellular component nucleolar part Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nuc (more detail) 176 NA Homo sapiens

GOA MEX001238 Genes associated with Kinase Inhibitor A 674563 Genes associated with Kinase Inhibitor A-674563, curated by the Drug Signature Database (DSigDB). (more detail) 75 25990557 Homo sapiens

DSigDB FEX016799 The diagnosis of Seminoma, NOS (stage ib) in Testis, NOS (TCGA S6 A8JX FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 276 25613900 Homo sapiens

HPA-TCGA FOX000132 Neighborhood of EIF3S6 Neighborhood of EIF3S6 eukaryotic translation initiation factor 3, subunit 6 48kDa in the GNF2 expr (more detail) 116 NA Homo sapiens

MSigDB IEI007848 Protein protein interactors of human gene MED19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED19 (SwissProt ID= (more detail) 121 17535438 Homo sapiens

I2D IEI008634 Protein protein interactors of human gene NCOA3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCOA3 (SwissProt ID= (more detail) 121 17535438 Homo sapiens

I2D WIG001204 Genes involved in Signaling by FGFR in disease (more detail) 121 NA Homo sapiens

MSigDB WEX000012 Cell Cycle The genes related to cell cycle (cell function) in tumor using next-generation sequencer (NGS) reado (more detail) 167 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas FAX000485 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif TTTSGCGS. Mo (more detail) 215 NA Homo sapiens

MSigDB IEI013681 Protein protein interactors of human gene THRAP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THRAP3 (SwissProt ID (more detail) 100 17535438 Homo sapiens

I2D TAX013489 GO:0000784 cellular component nuclear chromosome, telomeric region The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and assoc (more detail) 100 NA Homo sapiens

GOA IEI011551 Protein protein interactors of human gene RPL9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL9 (SwissProt ID=P (more detail) 169 17535438 Homo sapiens

I2D IEI005480 Protein protein interactors of human gene GRB10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRB10 (SwissProt ID= (more detail) 188 17535438 Homo sapiens

I2D MAX000950 Up regulated genes in both rectal and colon carcinoma compared to normal mucosa samples. To characterize patterns of global transcriptional deregulation in primary colon carcinomas, we did (more detail) 264 NA Homo sapiens

MSigDB IEI011800 Protein protein interactors of human gene SART1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SART1 (SwissProt ID= (more detail) 97 17535438 Homo sapiens

I2D TAX025702 GO:0046677 biological process response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 285 NA Homo sapiens

GOA WIG001579 JAK/STAT Pathway JAK/STAT Pathway (more detail) 285 NA Homo sapiens

Protein Lounge IEI010648 Protein protein interactors of human gene PSMD11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD11 (SwissProt ID (more detail) 113 17535438 Homo sapiens

I2D TAX035125 GO:2001251 biological process negative regulation of chromosome organization Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization (more detail) 113 NA Homo sapiens

GOA MEX003659 Genes associated with Perturbagen Signature MS 275 Genes associated with Perturbagen Signature MS-275, curated by the Drug Signature Database (DSigDB). (more detail) 283 25990557 Homo sapiens

DSigDB TAX023687 GO:0042133 biological process neurotransmitter metabolic process The chemical reactions and pathways involving neurotransmitters, any of a group of substances that a (more detail) 88 NA Homo sapiens

GOA TAX001309 Genes annotated by the GO term GO:0004721. Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity. (more detail) 78 NA Homo sapiens

MSigDB TAX017649 GO:0009301 biological process snRNA transcription The synthesis of small nuclear RNA (snRNA) from a DNA template. (more detail) 70 NA Homo sapiens

GOA TAX024022 GO:0042795 biological process snRNA transcription by RNA polymerase II The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), origin (more detail) 70 NA Homo sapiens

GOA IEI014487 Protein protein interactors of human gene TUFM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TUFM (SwissProt ID=P (more detail) 200 17535438 Homo sapiens

I2D MAX000614 Genes up regulated in HEK293 cells (embryonic kidney) at 6 h, 12 h or 24 h after infection with reovirus strain T3A (known as a strong inducer of apoptosis). Reoviruses are a leading model for understanding cellular mechanisms of virus-induced apoptosis. Reo (more detail) 292 NA Homo sapiens

MSigDB TAX028955 GO:0070482 biological process response to oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 290 NA Homo sapiens

GOA FAX000487 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif TTTSGCGS. Mo (more detail) 212 NA Homo sapiens

MSigDB MAX000151 Set 'Oct4 targets': genes upregulated and identified by ChIP on chip as OCT4 [GeneID=5460] transcription factor targets in human embryonic stem cells. Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear, howev (more detail) 269 NA Homo sapiens

MSigDB MOX002750 Genes associated with Computational Drug Signature LY 294002 Genes associated with Computational Drug Signature LY 294002, curated by the Drug Signature Database (more detail) 226 25990557 Homo sapiens

DSigDB MOX015198 Genes associated with Computational Drug Signature staurosporine Genes associated with Computational Drug Signature staurosporine, curated by the Drug Signature Data (more detail) 120 25990557 Homo sapiens

DSigDB IEI004189 Protein protein interactors of human gene EPAS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPAS1 (SwissProt ID= (more detail) 115 17535438 Homo sapiens

I2D TAX017049 GO:0008080 molecular function N acetyltransferase activity Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. (more detail) 81 NA Homo sapiens

GOA IEI005785 Protein protein interactors of human gene HECW2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HECW2 (SwissProt ID= (more detail) 282 17535438 Homo sapiens

I2D TAX030060 GO:0072562 cellular component blood microparticle A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood (more detail) 191 NA Homo sapiens

GOA IEI011505 Protein protein interactors of human gene RPL13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL13 (SwissProt ID= (more detail) 174 17535438 Homo sapiens

I2D IEI010544 Protein protein interactors of human gene PRPF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRPF8 (SwissProt ID= (more detail) 143 17535438 Homo sapiens

I2D IEI005753 Protein protein interactors of human gene HDAC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDAC4 (SwissProt ID= (more detail) 207 17535438 Homo sapiens

I2D IEI000362 Protein protein interactors of human gene AGO2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AGO2 (SwissProt ID=Q (more detail) 233 17535438 Homo sapiens

I2D IEI002967 Protein protein interactors of human gene CREB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CREB1 (SwissProt ID= (more detail) 227 17535438 Homo sapiens

I2D TAX025189 GO:0045637 biological process regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of myeloid cell differentiation. (more detail) 215 NA Homo sapiens

GOA IEI001028 Protein protein interactors of human gene ATG14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATG14 (SwissProt ID= (more detail) 221 17535438 Homo sapiens

I2D TAX025464 GO:0046128 biological process purine ribonucleoside metabolic process The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base (more detail) 69 NA Homo sapiens

GOA TAX025585 GO:0046470 biological process phosphatidylcholine metabolic process The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospho (more detail) 69 NA Homo sapiens

GOA TAX019692 GO:0019363 biological process pyridine nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotid (more detail) 69 NA Homo sapiens

GOA TAX019690 GO:0019359 biological process nicotinamide nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucl (more detail) 69 NA Homo sapiens

GOA IEI003101 Protein protein interactors of human gene CTBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTBP1 (SwissProt ID= (more detail) 124 17535438 Homo sapiens

I2D IEI014582 Protein protein interactors of human gene UBE2L3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2L3 (SwissProt ID (more detail) 114 17535438 Homo sapiens

I2D FEX002192 Lymphoma Jenner03 279genes Fig. 8.Detail of the proliferation signature. This gene expression signature is enriched for genes i (more detail) 149 12925741 Homo sapiens

GeneSigDB FOX000420 Neighborhood of UBE2I Neighborhood of UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) in the MORF expression (more detail) 232 NA Homo sapiens

MSigDB IEI006633 Protein protein interactors of human gene KAT5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KAT5 (SwissProt ID=Q (more detail) 218 17535438 Homo sapiens

I2D MAX001731 Genes down regulated in response to both hypoxia and overexpression of an active form of HIF1A [GeneID=3091]. Hypoxia-inducible factor 1 (HIF-1) activates transcription of genes encoding angiogenic growth facto (more detail) 263 NA Homo sapiens

MSigDB TAX032529 GO:1902493 cellular component acetyltransferase complex A protein complex which is capable of acetyltransferase activity. (more detail) 89 NA Homo sapiens

GOA TAX020874 GO:0031248 cellular component protein acetyltransferase complex A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule. (more detail) 89 NA Homo sapiens

GOA IEI005901 Protein protein interactors of human gene HMGB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMGB1 (SwissProt ID= (more detail) 108 17535438 Homo sapiens

I2D TAX017480 GO:0009064 biological process glutamine family amino acid metabolic process The chemical reactions and pathways involving amino acids of the glutamine family, comprising argini (more detail) 68 NA Homo sapiens

GOA TAX019773 GO:0019674 biological process NAD metabolic process The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme pr (more detail) 68 NA Homo sapiens

GOA TAX017111 GO:0008186 molecular function RNA dependent ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, (more detail) 68 NA Homo sapiens

GOA TAX014777 GO:0003724 molecular function RNA helicase activity Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a RNA helix. (more detail) 68 NA Homo sapiens

GOA TAX016081 GO:0006026 biological process aminoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containi (more detail) 68 NA Homo sapiens

GOA TAX016271 GO:0006353 biological process DNA templated transcription, termination The cellular process that completes DNA-templated transcription; the formation of phosphodiester bon (more detail) 68 NA Homo sapiens

GOA TAX013608 GO:0001085 molecular function RNA polymerase II transcription factor binding Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any prote (more detail) 118 NA Homo sapiens

GOA TAX017815 GO:0009952 biological process anterior/posterior pattern specification The regionalization process in which specific areas of cell differentiation are determined along the (more detail) 137 NA Homo sapiens

GOA FOX000280 Neighborhood of DEK Neighborhood of DEK DEK oncogene (DNA binding) in the MORF expression compendium (more detail) 249 NA Homo sapiens

MSigDB IEI014560 Protein protein interactors of human gene UBB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBB (SwissProt ID=P0 (more detail) 168 17535438 Homo sapiens

I2D IEI008272 Protein protein interactors of human gene MSH2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MSH2 (SwissProt ID=P (more detail) 130 17535438 Homo sapiens

I2D TAX026643 GO:0050864 biological process regulation of B cell activation Any process that modulates the frequency, rate or extent of B cell activation. (more detail) 170 NA Homo sapiens

GOA TAX032649 GO:1902806 biological process regulation of cell cycle G1/S phase transition Any process that modulates the frequency, rate or extent of cell cycle G1/S phase transition. (more detail) 157 NA Homo sapiens

GOA IEI015094 Protein protein interactors of human gene WWOX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WWOX (SwissProt ID=Q (more detail) 241 17535438 Homo sapiens

I2D IEI011589 Protein protein interactors of human gene RPS26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS26 (SwissProt ID= (more detail) 132 17535438 Homo sapiens

I2D WIG001008 Genes involved in M/G1 Transition (more detail) 79 NA Homo sapiens

MSigDB TAX026242 GO:0048608 biological process reproductive structure development The reproductive developmental process whose specific outcome is the progression of structures that (more detail) 262 NA Homo sapiens

GOA FAX000474 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F
TFDP1: transcription factor Dp 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTSGCGS (more detail) 209 NA Homo sapiens

MSigDB FAX000476 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif NTTTCGCGCS which matches annotation for E2F1: E2F transcription factor 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif NTTTCGCG (more detail) 221 NA Homo sapiens

MSigDB IEI003376 Protein protein interactors of human gene DCUN1D1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCUN1D1 (SwissProt I (more detail) 219 17535438 Homo sapiens

I2D IEI015121 Protein protein interactors of human gene XPO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XPO1 (SwissProt ID=O (more detail) 213 17535438 Homo sapiens

I2D WIG001835 TLR Signaling Toll-like receptors (TLRs) are important sensors of foreign microbial components as well as products (more detail) 161 NA Homo sapiens

Spike WIG000808 Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) (more detail) 94 NA Homo sapiens

MSigDB IEI011515 Protein protein interactors of human gene RPL22 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL22 (SwissProt ID= (more detail) 141 17535438 Homo sapiens

I2D IEI013088 Protein protein interactors of human gene STAT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAT1 (SwissProt ID= (more detail) 254 17535438 Homo sapiens

I2D TAX019035 GO:0016458 biological process gene silencing Any process carried out at the cellular level that results in either long-term transcriptional repre (more detail) 91 NA Homo sapiens

GOA TAX033852 GO:1905269 biological process positive regulation of chromatin organization Any process that activates or increases the frequency, rate or extent of chromatin organization. (more detail) 91 NA Homo sapiens

GOA IEI011569 Protein protein interactors of human gene RPS10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS10 (SwissProt ID= (more detail) 154 17535438 Homo sapiens

I2D IEI012595 Protein protein interactors of human gene SMARCC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCC1 (SwissProt I (more detail) 112 17535438 Homo sapiens

I2D MOX016167 Genes associated with Computational Drug Signature 2 Butanone Genes associated with Computational Drug Signature 2-Butanone, curated by the Drug Signature Databas (more detail) 194 25990557 Homo sapiens

DSigDB IEI007695 Protein protein interactors of human gene MAPK8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPK8 (SwissProt ID= (more detail) 194 17535438 Homo sapiens

I2D TAX014910 GO:0004004 molecular function ATP dependent RNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA (more detail) 67 NA Homo sapiens

GOA TAX032776 GO:1903052 biological process positive regulation of proteolysis involved in cellular protein catabolic process Any process that activates or increases the frequency, rate or extent of proteolysis involved in cel (more detail) 124 NA Homo sapiens

GOA WIG001528 GPCR Pathway GPCR Pathway (more detail) 214 NA Homo sapiens

Protein Lounge IEI008632 Protein protein interactors of human gene NCOA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCOA1 (SwissProt ID= (more detail) 93 17535438 Homo sapiens

I2D IEI011615 Protein protein interactors of human gene RPS9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS9 (SwissProt ID=P (more detail) 181 17535438 Homo sapiens

I2D WEX000077 Oxidative Stress The genes related to oxidative stress (cell function) in tumor, immune, stroma using next-generation (more detail) 151 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI011501 Protein protein interactors of human gene RPL10A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL10A (SwissProt ID (more detail) 142 17535438 Homo sapiens

I2D IEI011070 Protein protein interactors of human gene RBM14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM14 (SwissProt ID= (more detail) 142 17535438 Homo sapiens

I2D IEI008796 Protein protein interactors of human gene NFKB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFKB2 (SwissProt ID= (more detail) 185 17535438 Homo sapiens

I2D TAX000411 Genes annotated by the GO term GO:0000122. Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. (more detail) 81 NA Homo sapiens

MSigDB WIG001842 p53 Signaling Network This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target (more detail) 168 NA Homo sapiens

Spike IEI004105 Protein protein interactors of human gene ELOC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELOC (SwissProt ID=Q (more detail) 116 17535438 Homo sapiens

I2D IEI012596 Protein protein interactors of human gene SMARCC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCC2 (SwissProt I (more detail) 116 17535438 Homo sapiens

I2D IEI011581 Protein protein interactors of human gene RPS19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS19 (SwissProt ID= (more detail) 155 17535438 Homo sapiens

I2D TAX032376 GO:1902105 biological process regulation of leukocyte differentiation Any process that modulates the frequency, rate or extent of leukocyte differentiation. (more detail) 258 NA Homo sapiens

GOA IEI012980 Protein protein interactors of human gene SRPK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRPK1 (SwissProt ID= (more detail) 256 17535438 Homo sapiens

I2D TAX001272 Genes annotated by the GO term GO:0000166. Interacting selectively with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose moiety. (more detail) 217 NA Homo sapiens

MSigDB IEI006993 Protein protein interactors of human gene KPNB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KPNB1 (SwissProt ID= (more detail) 207 17535438 Homo sapiens

I2D IEI007837 Protein protein interactors of human gene MED10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED10 (SwissProt ID= (more detail) 74 17535438 Homo sapiens

I2D TAX021507 GO:0032392 biological process DNA geometric change The process in which a transformation is induced in the geometry of a DNA double helix, resulting in (more detail) 66 NA Homo sapiens

GOA TAX015199 GO:0004521 molecular function endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. (more detail) 66 NA Homo sapiens

GOA WAG000600 Ribosome (more detail) 66 NA Homo sapiens

KEGG TAX022372 GO:0034212 molecular function peptide N acetyltransferase activity Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reac (more detail) 66 NA Homo sapiens

GOA TAX000067 Genes annotated by the GO term GO:0005975. The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. (more detail) 176 NA Homo sapiens

MSigDB TAX031681 GO:0140030 molecular function modification dependent protein binding Interacting selectively and non-covalently with a protein upon post-translation modification of the (more detail) 132 NA Homo sapiens

GOA WIG001104 Genes involved in Processing of Capped Intron Containing Pre mRNA (more detail) 132 NA Homo sapiens

MSigDB TAX021053 GO:0031570 biological process DNA integrity checkpoint A cell cycle process that controls cell cycle progression in response to changes in DNA structure by (more detail) 77 NA Homo sapiens

GOA IEI005762 Protein protein interactors of human gene HDGF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDGF (SwissProt ID=P (more detail) 184 17535438 Homo sapiens

I2D FEX016122 The diagnosis of Seminoma, NOS (stage ib) in Testis, NOS (TCGA YU A90Q FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 261 25613900 Homo sapiens

HPA-TCGA IEI010680 Protein protein interactors of human gene PTBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTBP1 (SwissProt ID= (more detail) 141 17535438 Homo sapiens

I2D TAX016970 GO:0007568 biological process aging A developmental process that is a deterioration and loss of function over time. Aging includes loss (more detail) 228 NA Homo sapiens

GOA TAX034444 GO:2000045 biological process regulation of G1/S transition of mitotic cell cycle Any cell cycle regulatory process that controls the commitment of a cell from G1 to S phase of the m (more detail) 143 NA Homo sapiens

GOA IEI006076 Protein protein interactors of human gene HSPA9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSPA9 (SwissProt ID= (more detail) 247 17535438 Homo sapiens

I2D TAX000358 Genes annotated by the GO term GO:0006397. Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. (more detail) 73 NA Homo sapiens

MSigDB TAX016366 GO:0006487 biological process protein N linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to (more detail) 65 NA Homo sapiens

GOA TAX001228 Genes annotated by the GO term GO:0016879. Catalysis of the ligation of two substances via a carbon nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. (more detail) 65 NA Homo sapiens

MSigDB MEX001550 Genes associated with Kinase Inhibitor Cyt387 Genes associated with Kinase Inhibitor Cyt387, curated by the Drug Signature Database (DSigDB). (more detail) 65 25990557 Homo sapiens

DSigDB TAX022673 GO:0034968 biological process histone lysine methylation The modification of a histone by addition of one or more methyl groups to a lysine residue. (more detail) 65 NA Homo sapiens

GOA TAX014759 GO:0003684 molecular function damaged DNA binding Interacting selectively and non-covalently with damaged DNA. (more detail) 65 NA Homo sapiens

GOA TAX031096 GO:0098727 biological process maintenance of cell number Any process by which the numbers of cells of a particular type or in a tissue are maintained. (more detail) 124 NA Homo sapiens

GOA WIG000493 Cell cycle Mitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replic (more detail) 124 NA Homo sapiens

MSigDB IEI006087 Protein protein interactors of human gene HSPD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSPD1 (SwissProt ID= (more detail) 256 17535438 Homo sapiens

I2D TAX017761 GO:0009755 biological process hormone mediated signaling pathway A series of molecular signals mediated by the detection of a hormone. (more detail) 168 NA Homo sapiens

GOA IEI005329 Protein protein interactors of human gene GNL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GNL3 (SwissProt ID=Q (more detail) 88 17535438 Homo sapiens

I2D IEI009418 Protein protein interactors of human gene PA2G4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PA2G4 (SwissProt ID= (more detail) 114 17535438 Homo sapiens

I2D MEX001926 Genes associated with Kinase Inhibitor AGN PC 045KSD Genes associated with Kinase Inhibitor AGN-PC-045KSD, curated by the Drug Signature Database (DSigDB (more detail) 85 25990557 Homo sapiens

DSigDB TAX017118 GO:0008194 molecular function UDP glycosyltransferase activity Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule. (more detail) 144 NA Homo sapiens

GOA IEI007890 Protein protein interactors of human gene MEPCE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEPCE (SwissProt ID= (more detail) 174 17535438 Homo sapiens

I2D IEI009553 Protein protein interactors of human gene PCBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCBP2 (SwissProt ID= (more detail) 121 17535438 Homo sapiens

I2D TAX019831 GO:0019827 biological process stem cell population maintenance The process by which an organism or tissue maintains a population of stem cells of a single type. T (more detail) 121 NA Homo sapiens

GOA IEI012583 Protein protein interactors of human gene SMAD7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMAD7 (SwissProt ID= (more detail) 96 17535438 Homo sapiens

I2D IEI002039 Protein protein interactors of human gene CCND1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCND1 (SwissProt ID= (more detail) 128 17535438 Homo sapiens

I2D IEI003646 Protein protein interactors of human gene DNAJA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJA1 (SwissProt ID (more detail) 182 17535438 Homo sapiens

I2D TAX000028 Genes annotated by the GO term GO:0006520. The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents. (more detail) 72 NA Homo sapiens

MSigDB IEI011102 Protein protein interactors of human gene RBMX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBMX (SwissProt ID=P (more detail) 116 17535438 Homo sapiens

I2D IEI014863 Protein protein interactors of human gene VDR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VDR (SwissProt ID=P1 (more detail) 116 17535438 Homo sapiens

I2D TAX021097 GO:0031647 biological process regulation of protein stability Any process that affects the structure and integrity of a protein, altering the likelihood of its de (more detail) 251 NA Homo sapiens

GOA TAX026208 GO:0048534 biological process hematopoietic or lymphoid organ development The process whose specific outcome is the progression of any organ involved in hematopoiesis (also k (more detail) 163 NA Homo sapiens

GOA TAX032894 GO:1903322 biological process positive regulation of protein modification by small protein conjugation or removal Any process that activates or increases the frequency, rate or extent of protein modification by sma (more detail) 123 NA Homo sapiens

GOA TAX016575 GO:0006754 biological process ATP biosynthetic process The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a (more detail) 64 NA Homo sapiens

GOA FOX000515 Genes in the cancer module 183 (more detail) 64 NA Homo sapiens

MSigDB IEI014545 Protein protein interactors of human gene UBA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBA1 (SwissProt ID=P (more detail) 202 17535438 Homo sapiens

I2D TAX001343 Genes annotated by the GO term GO:0017076. Interacting selectively with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate. (more detail) 204 NA Homo sapiens

MSigDB MAX000766 Genes required for proliferation of DLD 1 cell (colon cancer with APC [GeneID=324] deletions), based on shRNA screen. Aberrant activation of the canonical WNT/beta-catenin pathway occurs in almost all colorectal cancer (more detail) 165 NA Homo sapiens

MSigDB WIG000980 Genes involved in Metabolism of nucleotides (more detail) 68 NA Homo sapiens

MSigDB IEI007657 Protein protein interactors of human gene MAP3K14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP3K14 (SwissProt I (more detail) 141 17535438 Homo sapiens

I2D TAX019001 GO:0016407 molecular function acetyltransferase activity Catalysis of the transfer of an acetyl group to an acceptor molecule. (more detail) 98 NA Homo sapiens

GOA IEI010543 Protein protein interactors of human gene PRPF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRPF6 (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D TAX032261 GO:1901800 biological process positive regulation of proteasomal protein catabolic process Any process that activates or increases the frequency, rate or extent of proteasomal protein catabol (more detail) 108 NA Homo sapiens

GOA TAX020781 GO:0031058 biological process positive regulation of histone modification Any process that activates or increases the frequency, rate or extent of the covalent alteration of (more detail) 84 NA Homo sapiens

GOA FAX000481 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif TTTSGCGCGMNR. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif TTTSGCGCGMNR (more detail) 227 NA Homo sapiens

MSigDB TAX021547 GO:0032434 biological process regulation of proteasomal ubiquitin dependent protein catabolic process Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by (more detail) 127 NA Homo sapiens

GOA TAX024492 GO:0043648 biological process dicarboxylic acid metabolic process The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two ca (more detail) 95 NA Homo sapiens

GOA FOX000503 Genes in the cancer module 172 (more detail) 95 NA Homo sapiens

MSigDB FOX000237 Neighborhood of ACTG1 Neighborhood of ACTG1 actin, gamma 1 in the MORF expression compendium (more detail) 136 NA Homo sapiens

MSigDB IEI002273 Protein protein interactors of human gene CDKN2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDKN2A (SwissProt ID (more detail) 185 17535438 Homo sapiens

I2D TAX019243 GO:0016829 molecular function lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxid (more detail) 187 NA Homo sapiens

GOA WIG001961 TGF beta Signaling Pathway TGF beta Signaling Pathway (more detail) 115 NA Homo sapiens

WikiPathway IEI013269 Protein protein interactors of human gene SYNCRIP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SYNCRIP (SwissProt I (more detail) 209 17535438 Homo sapiens

I2D TAX021011 GO:0031463 cellular component Cul3 RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form (more detail) 71 NA Homo sapiens

GOA WIG001828 Hearing related SIX1 Interaction The PAX, EYA, SIX and DACH gene families are important in otic development. The SIX1 network shows t (more detail) 164 NA Homo sapiens

Spike IEI010645 Protein protein interactors of human gene PSMC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMC6 (SwissProt ID= (more detail) 122 17535438 Homo sapiens

I2D IEI008276 Protein protein interactors of human gene MSH6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MSH6 (SwissProt ID=P (more detail) 92 17535438 Homo sapiens

I2D IEI000717 Protein protein interactors of human gene APEX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APEX1 (SwissProt ID= (more detail) 105 17535438 Homo sapiens

I2D TAX026594 GO:0050792 biological process regulation of viral process Any process that modulates the rate or extent of the viral life cycle, the set of processes by which (more detail) 168 NA Homo sapiens

GOA IEI011554 Protein protein interactors of human gene RPLP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPLP1 (SwissProt ID= (more detail) 168 17535438 Homo sapiens

I2D TAX017579 GO:0009185 biological process ribonucleoside diphosphate metabolic process The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of (more detail) 63 NA Homo sapiens

GOA TAX020516 GO:0030433 biological process ubiquitin dependent ERAD pathway The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation (more detail) 63 NA Homo sapiens

GOA TAX016571 GO:0006749 biological process glutathione metabolic process The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, (more detail) 63 NA Homo sapiens

GOA MEX002414 Genes associated with Kinase Inhibitor Ruzolitinib Genes associated with Kinase Inhibitor Ruzolitinib, curated by the Drug Signature Database (DSigDB). (more detail) 63 25990557 Homo sapiens

DSigDB TAX032182 GO:1901607 biological process alpha amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of an alpha-amino acid. (more detail) 63 NA Homo sapiens

GOA TAX024983 GO:0045165 biological process cell fate commitment The commitment of cells to specific cell fates and their capacity to differentiate into particular k (more detail) 140 NA Homo sapiens

GOA TAX019675 GO:0019318 biological process hexose metabolic process The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbo (more detail) 153 NA Homo sapiens

GOA TAX000157 Genes annotated by the GO term GO:0016311. The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. (more detail) 67 NA Homo sapiens

MSigDB FOX000126 Neighborhood of DAP3 Neighborhood of DAP3 death associated protein 3 in the GNF2 expression compendium (more detail) 112 NA Homo sapiens

MSigDB TAX029286 GO:0071103 biological process DNA conformation change A cellular process that results in a change in the spatial configuration of a DNA molecule. A confor (more detail) 107 NA Homo sapiens

GOA TAX032909 GO:1903364 biological process positive regulation of cellular protein catabolic process Any process that activates or increases the frequency, rate or extent of cellular protein catabolic (more detail) 144 NA Homo sapiens

GOA FAX000486 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif NCSCGCSAAAN which matches annotation for E2F
TFDP1: transcription factor Dp 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif NCSCGCSA (more detail) 216 NA Homo sapiens

MSigDB IEI014707 Protein protein interactors of human gene UPF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UPF1 (SwissProt ID=Q (more detail) 126 17535438 Homo sapiens

I2D IEI007814 Protein protein interactors of human gene MDC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MDC1 (SwissProt ID=Q (more detail) 184 17535438 Homo sapiens

I2D TAX014119 GO:0002218 biological process activation of innate immune response Any process that initiates an innate immune response. Innate immune responses are defense responses (more detail) 186 NA Homo sapiens

GOA IEI012376 Protein protein interactors of human gene SLC25A5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC25A5 (SwissProt I (more detail) 212 17535438 Homo sapiens

I2D WIG000904 Genes involved in HIV Infection (more detail) 188 NA Homo sapiens

MSigDB TAX016581 GO:0006767 biological process water soluble vitamin metabolic process The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in (more detail) 80 NA Homo sapiens

GOA TAX001344 Genes annotated by the GO term GO:0032555. Interacting selectively with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. (more detail) 198 NA Homo sapiens

MSigDB TAX029492 GO:0071478 biological process cellular response to radiation Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 148 NA Homo sapiens

GOA TAX001311 Genes annotated by the GO term GO:0042578. Catalysis of the reaction: RPO R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3. (more detail) 148 NA Homo sapiens

MSigDB IEI005587 Protein protein interactors of human gene GTF2I from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2I (SwissProt ID= (more detail) 121 17535438 Homo sapiens

I2D TAX024909 GO:0045047 biological process protein targeting to ER The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained wit (more detail) 99 NA Homo sapiens

GOA FOX000057 Neighborhood of NPM1 Neighborhood of NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) in the GCM expression c (more detail) 109 NA Homo sapiens

MSigDB IEI010624 Protein protein interactors of human gene PSMA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMA4 (SwissProt ID= (more detail) 91 17535438 Homo sapiens

I2D IEI011706 Protein protein interactors of human gene RUNX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RUNX1 (SwissProt ID= (more detail) 91 17535438 Homo sapiens

I2D IEI013333 Protein protein interactors of human gene TADA2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TADA2A (SwissProt ID (more detail) 139 17535438 Homo sapiens

I2D MAX000570 Genes up regulated by MYC [GeneID=4609] and whose promoters are bound by MYC, according to MYC Target Gene Database. We report a database of genes responsive to the Myc oncogenic transcription factor. The database Myc (more detail) 139 NA Homo sapiens

MSigDB IEI015108 Protein protein interactors of human gene XIAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XIAP (SwissProt ID=P (more detail) 130 17535438 Homo sapiens

I2D IEI005756 Protein protein interactors of human gene HDAC7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDAC7 (SwissProt ID= (more detail) 123 17535438 Homo sapiens

I2D WIG001836 MAPK signaling The transmission of extracellular signals into their intracellular targets is mediated by a network (more detail) 141 NA Homo sapiens

Spike MOX004038 Genes associated with Computational Drug Signature ellagic acid Genes associated with Computational Drug Signature ellagic acid, curated by the Drug Signature Datab (more detail) 141 25990557 Homo sapiens

DSigDB TAX018954 GO:0016279 molecular function protein lysine N methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group (more detail) 62 NA Homo sapiens

GOA TAX016358 GO:0006476 biological process protein deacetylation The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from ac (more detail) 62 NA Homo sapiens

GOA TAX015212 GO:0004536 molecular function deoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. (more detail) 62 NA Homo sapiens

GOA IEI005899 Protein protein interactors of human gene HMGA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMGA1 (SwissProt ID= (more detail) 88 17535438 Homo sapiens

I2D IEI007795 Protein protein interactors of human gene MCM3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCM3 (SwissProt ID=P (more detail) 143 17535438 Homo sapiens

I2D TAX024009 GO:0042770 biological process signal transduction in response to DNA damage A cascade of processes induced by the detection of DNA damage within a cell. (more detail) 101 NA Homo sapiens

GOA TAX015806 GO:0005576 cellular component extracellular region The space external to the outermost structure of a cell. For cells without external protective or ex (more detail) 1840 NA Homo sapiens

GOA TAX024529 GO:0043903 biological process regulation of symbiosis, encompassing mutualism through parasitism Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two or (more detail) 195 NA Homo sapiens

GOA IEI010512 Protein protein interactors of human gene PRMT5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRMT5 (SwissProt ID= (more detail) 160 17535438 Homo sapiens

I2D IEI006063 Protein protein interactors of human gene HSP90B1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSP90B1 (SwissProt I (more detail) 145 17535438 Homo sapiens

I2D TAX013265 GO:0000123 cellular component histone acetyltransferase complex A protein complex that possesses histone acetyltransferase activity. (more detail) 79 NA Homo sapiens

GOA IEI008163 Protein protein interactors of human gene MRE11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRE11 (SwissProt ID= (more detail) 93 17535438 Homo sapiens

I2D TAX017001 GO:0007623 biological process circadian rhythm Any biological process in an organism that recurs with a regularity of approximately 24 hours. (more detail) 136 NA Homo sapiens

GOA IEI011054 Protein protein interactors of human gene RBBP7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBBP7 (SwissProt ID= (more detail) 127 17535438 Homo sapiens

I2D IEI010934 Protein protein interactors of human gene RAD21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD21 (SwissProt ID= (more detail) 228 17535438 Homo sapiens

I2D IEI010622 Protein protein interactors of human gene PSMA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMA2 (SwissProt ID= (more detail) 120 17535438 Homo sapiens

I2D IEI002463 Protein protein interactors of human gene CHD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD3 (SwissProt ID=Q (more detail) 149 17535438 Homo sapiens

I2D WEX000019 Differentiation The genes related to differentiation (cell function) in tumor using next-generation sequencer (NGS) (more detail) 224 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas WIG001200 Genes involved in Signaling by FGFR (more detail) 108 NA Homo sapiens

MSigDB TAX019125 GO:0016605 cellular component PML body A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cel (more detail) 98 NA Homo sapiens

GOA MOX017879 Genes associated with Computational Drug Signature resveratrol Genes associated with Computational Drug Signature resveratrol, curated by the Drug Signature Databa (more detail) 222 25990557 Homo sapiens

DSigDB IEI011573 Protein protein interactors of human gene RPS12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS12 (SwissProt ID= (more detail) 103 17535438 Homo sapiens

I2D IEI014573 Protein protein interactors of human gene UBE2E3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2E3 (SwissProt ID (more detail) 103 17535438 Homo sapiens

I2D FAX000326 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif SGCGSSAAA which matches annotation for E2F1: E2F transcription factor 1
TFDP1: transcription factor Dp 1
RB1: retinoblastoma 1 (including osteosarcoma) Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif SGCGSSAA (more detail) 153 NA Homo sapiens

MSigDB IEI009552 Protein protein interactors of human gene PCBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCBP1 (SwissProt ID= (more detail) 153 17535438 Homo sapiens

I2D FAX000483 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif TTTCGCGC. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif TTTCGCGC. Mo (more detail) 206 NA Homo sapiens

MSigDB IEI001824 Protein protein interactors of human gene CASP8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASP8 (SwissProt ID= (more detail) 204 17535438 Homo sapiens

I2D IEI008308 Protein protein interactors of human gene MTA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTA2 (SwissProt ID=O (more detail) 110 17535438 Homo sapiens

I2D TAX017573 GO:0009179 biological process purine ribonucleoside diphosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisti (more detail) 61 NA Homo sapiens

GOA TAX017103 GO:0008173 molecular function RNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule. (more detail) 61 NA Homo sapiens

GOA TAX017533 GO:0009135 biological process purine nucleoside diphosphate metabolic process The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting o (more detail) 61 NA Homo sapiens

GOA TAX017654 GO:0009308 biological process amine metabolic process The chemical reactions and pathways involving any organic compound that is weakly basic in character (more detail) 61 NA Homo sapiens

GOA TAX016082 GO:0006027 biological process glycosaminoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a g (more detail) 61 NA Homo sapiens

GOA MEX001543 Genes associated with Kinase Inhibitor Ruxolitinib Genes associated with Kinase Inhibitor Ruxolitinib, curated by the Drug Signature Database (DSigDB). (more detail) 61 25990557 Homo sapiens

DSigDB IEI011580 Protein protein interactors of human gene RPS18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS18 (SwissProt ID= (more detail) 159 17535438 Homo sapiens

I2D FOX000417 Neighborhood of TPT1 Neighborhood of TPT1 tumor protein, translationally-controlled 1 in the MORF expression compendium (more detail) 100 NA Homo sapiens

MSigDB TAX000542 Genes annotated by the GO term GO:0030163. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. (more detail) 65 NA Homo sapiens

MSigDB IEI014336 Protein protein interactors of human gene TRRAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRRAP (SwissProt ID= (more detail) 84 17535438 Homo sapiens

I2D FOX000284 Neighborhood of EIF3S2 Neighborhood of EIF3S2 eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa in the MOR (more detail) 227 NA Homo sapiens

MSigDB IEI011970 Protein protein interactors of human gene SEM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SEM1 (SwissProt ID=P (more detail) 135 17535438 Homo sapiens

I2D IEI010640 Protein protein interactors of human gene PSMC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMC2 (SwissProt ID= (more detail) 126 17535438 Homo sapiens

I2D WAG000681 Formation of a pool of free 40S subunits (more detail) 92 NA Homo sapiens

Reactome TAX000132 Genes annotated by the GO term GO:0051276. A process that is carried out at the cellular level that results in the formation, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. (more detail) 119 NA Homo sapiens

MSigDB IEI010626 Protein protein interactors of human gene PSMA6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMA6 (SwissProt ID= (more detail) 137 17535438 Homo sapiens

I2D TAX016262 GO:0006338 biological process chromatin remodeling Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. The (more detail) 150 NA Homo sapiens

GOA TAX016473 GO:0006614 biological process SRP dependent cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation and is dependent upon two key (more detail) 89 NA Homo sapiens

GOA FOX000238 Neighborhood of ANP32B Neighborhood of ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B in the MORF (more detail) 187 NA Homo sapiens

MSigDB IEI007839 Protein protein interactors of human gene MED12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED12 (SwissProt ID= (more detail) 68 17535438 Homo sapiens

I2D TAX013243 GO:0000077 biological process DNA damage checkpoint A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. (more detail) 68 NA Homo sapiens

GOA IEI002254 Protein protein interactors of human gene CDK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK4 (SwissProt ID=P (more detail) 158 17535438 Homo sapiens

I2D IEI012594 Protein protein interactors of human gene SMARCB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCB1 (SwissProt I (more detail) 123 17535438 Homo sapiens

I2D WIG001221 Genes involved in Signaling by the B Cell Receptor (BCR) (more detail) 123 NA Homo sapiens

MSigDB IEI011523 Protein protein interactors of human gene RPL27A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL27A (SwissProt ID (more detail) 94 17535438 Homo sapiens

I2D FAX000473 Genes with promoter regions [ 2kb,2kb] around transcription start site containing the motif NTTSGCGG which matches annotation for E2F1: E2F transcription factor 1 Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif NTTSGCGG (more detail) 226 NA Homo sapiens

MSigDB TAX026650 GO:0050871 biological process positive regulation of B cell activation Any process that activates or increases the frequency, rate or extent of B cell activation. (more detail) 132 NA Homo sapiens

GOA TAX024870 GO:0044843 biological process cell cycle G1/S phase transition The cell cycle process by which a cell in G1 phase commits to S phase. (more detail) 99 NA Homo sapiens

GOA TAX019101 GO:0016575 biological process histone deacetylation The modification of histones by removal of acetyl groups. (more detail) 60 NA Homo sapiens

GOA TAX018946 GO:0016266 biological process O glycan processing The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-l (more detail) 60 NA Homo sapiens

GOA TAX017143 GO:0008235 molecular function metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus (more detail) 60 NA Homo sapiens

GOA TAX024826 GO:0044728 biological process DNA methylation or demethylation The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule (more detail) 60 NA Homo sapiens

GOA TAX016195 GO:0006220 biological process pyrimidine nucleotide metabolic process The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucl (more detail) 60 NA Homo sapiens

GOA TAX016383 GO:0006513 biological process protein monoubiquitination Addition of a single ubiquitin group to a protein. (more detail) 60 NA Homo sapiens

GOA MEX001346 Genes associated with Kinase Inhibitor WZ4002 Genes associated with Kinase Inhibitor WZ4002, curated by the Drug Signature Database (DSigDB). (more detail) 64 25990557 Homo sapiens

DSigDB IEI011555 Protein protein interactors of human gene RPLP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPLP2 (SwissProt ID= (more detail) 147 17535438 Homo sapiens

I2D FEX016802 The diagnosis of Seminoma, NOS (stage i) in Testis, NOS (TCGA XE AAOL FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 214 25613900 Homo sapiens

HPA-TCGA IEI011510 Protein protein interactors of human gene RPL17 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL17 (SwissProt ID= (more detail) 111 17535438 Homo sapiens

I2D IEI004104 Protein protein interactors of human gene ELOB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELOB (SwissProt ID=Q (more detail) 91 17535438 Homo sapiens

I2D FEX001584 Leukemia Sanchez Guijo08 77genes SuppTable2j Genes related to transcription (more detail) 74 18722011 Homo sapiens

GeneSigDB IEI008945 Protein protein interactors of human gene NOP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOP2 (SwissProt ID=P (more detail) 96 17535438 Homo sapiens

I2D IEI010221 Protein protein interactors of human gene POLR2E from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2E (SwissProt ID (more detail) 96 17535438 Homo sapiens

I2D TAX034457 GO:2000060 biological process positive regulation of ubiquitin dependent protein catabolic process Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein (more detail) 101 NA Homo sapiens

GOA IEI002464 Protein protein interactors of human gene CHD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD4 (SwissProt ID=Q (more detail) 120 17535438 Homo sapiens

I2D IEI005682 Protein protein interactors of human gene H3C15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H3C15 (SwissProt ID= (more detail) 113 17535438 Homo sapiens

I2D IEI012707 Protein protein interactors of human gene SNU13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNU13 (SwissProt ID= (more detail) 113 17535438 Homo sapiens

I2D TAX022787 GO:0035258 molecular function steroid hormone receptor binding Interacting selectively and non-covalently with a steroid hormone receptor. (more detail) 88 NA Homo sapiens

GOA WIG000702 Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins (more detail) 67 NA Homo sapiens

MSigDB IEI004667 Protein protein interactors of human gene FBXW7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXW7 (SwissProt ID= (more detail) 122 17535438 Homo sapiens

I2D IEI010627 Protein protein interactors of human gene PSMA7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMA7 (SwissProt ID= (more detail) 122 17535438 Homo sapiens

I2D TAX026798 GO:0051101 biological process regulation of DNA binding Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process (more detail) 115 NA Homo sapiens

GOA IEI012591 Protein protein interactors of human gene SMARCA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCA5 (SwissProt I (more detail) 103 17535438 Homo sapiens

I2D TAX013245 GO:0000082 biological process G1/S transition of mitotic cell cycle The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with (more detail) 98 NA Homo sapiens

GOA TAX000108 Genes annotated by the GO term GO:0022403. A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. (more detail) 167 NA Homo sapiens

MSigDB TAX023646 GO:0042054 molecular function histone methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-hi (more detail) 59 NA Homo sapiens

GOA MEX002406 Genes associated with Kinase Inhibitor Sorafenib Genes associated with Kinase Inhibitor Sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 59 25990557 Homo sapiens

DSigDB WAG000672 Cdc20:Phospho APC/C mediated degradation of Cyclin A (more detail) 59 NA Homo sapiens

Reactome WIG001146 Genes involved in Regulation of mRNA Stability by Proteins that Bind AU rich Elements (more detail) 82 NA Homo sapiens

MSigDB TAX000601 Genes annotated by the GO term GO:0051726. Any process that modulates the rate or extent of progression through the cell cycle. (more detail) 179 NA Homo sapiens

MSigDB TAX024416 GO:0043523 biological process regulation of neuron apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons. (more detail) 195 NA Homo sapiens

GOA TAX018953 GO:0016278 molecular function lysine N methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group (more detail) 63 NA Homo sapiens

GOA MEX002376 Genes associated with Kinase Inhibitor PHA 665752 Genes associated with Kinase Inhibitor PHA-665752, curated by the Drug Signature Database (DSigDB). (more detail) 63 25990557 Homo sapiens

DSigDB IEI005924 Protein protein interactors of human gene HNF4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNF4A (SwissProt ID= (more detail) 90 17535438 Homo sapiens

I2D IEI011593 Protein protein interactors of human gene RPS27L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS27L (SwissProt ID (more detail) 73 17535438 Homo sapiens

I2D IEI001212 Protein protein interactors of human gene BAG2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BAG2 (SwissProt ID=O (more detail) 152 17535438 Homo sapiens

I2D TAX029301 GO:0071156 biological process regulation of cell cycle arrest Any process that modulates the rate, frequency, or extent of cell cycle arrest, the process in which (more detail) 105 NA Homo sapiens

GOA IEI010938 Protein protein interactors of human gene RAD50 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD50 (SwissProt ID= (more detail) 76 17535438 Homo sapiens

I2D MAX002344 Genes constituting the XPRSS Int network: intersection of genes whose expression correlates with BRCA1, BRCA2, ATM, and CHEK2 [GeneID=672;675;472;11200] in a compendium of normal tissues. Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms (more detail) 160 NA Homo sapiens

MSigDB IEI010641 Protein protein interactors of human gene PSMC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMC3 (SwissProt ID= (more detail) 121 17535438 Homo sapiens

I2D TAX001312 Genes annotated by the GO term GO:0016791. Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. (more detail) 107 NA Homo sapiens

MSigDB IEI013000 Protein protein interactors of human gene SRSF5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF5 (SwissProt ID= (more detail) 114 17535438 Homo sapiens

I2D IEI007858 Protein protein interactors of human gene MED29 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED29 (SwissProt ID= (more detail) 92 17535438 Homo sapiens

I2D WIG000703 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (more detail) 66 NA Homo sapiens

MSigDB WAG000085 L13a mediated translational silencing of Ceruloplasmin expression (more detail) 102 NA Homo sapiens

Reactome IEI010509 Protein protein interactors of human gene PRMT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRMT1 (SwissProt ID= (more detail) 172 17535438 Homo sapiens

I2D IEI012262 Protein protein interactors of human gene SKP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SKP2 (SwissProt ID=Q (more detail) 123 17535438 Homo sapiens

I2D MOX016166 Genes associated with Computational Drug Signature water Genes associated with Computational Drug Signature water, curated by the Drug Signature Database (DS (more detail) 194 25990557 Homo sapiens

DSigDB IEI010936 Protein protein interactors of human gene RAD23A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD23A (SwissProt ID (more detail) 151 17535438 Homo sapiens

I2D TAX025820 GO:0046939 biological process nucleotide phosphorylation The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylate (more detail) 58 NA Homo sapiens

GOA TAX028564 GO:0061733 molecular function peptide lysine N acetyltransferase activity Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide. (more detail) 58 NA Homo sapiens

GOA TAX027224 GO:0051865 biological process protein autoubiquitination The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an ide (more detail) 58 NA Homo sapiens

GOA TAX016529 GO:0006687 biological process glycosphingolipid metabolic process The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphi (more detail) 58 NA Homo sapiens

GOA WIG000599 Prostate cancer The identification of key molecular alterations in prostate-cancer cells implicates carcinogen defen (more detail) 89 NA Homo sapiens

MSigDB WAG001218 Glycan structures biosynthesis 2 (more detail) 62 NA Homo sapiens

KEGG IEI001135 Protein protein interactors of human gene ATR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATR (SwissProt ID=Q1 (more detail) 99 17535438 Homo sapiens

I2D IEI001555 Protein protein interactors of human gene C1QBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C1QBP (SwissProt ID= (more detail) 209 17535438 Homo sapiens

I2D IEI001288 Protein protein interactors of human gene BCL6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCL6 (SwissProt ID=P (more detail) 161 17535438 Homo sapiens

I2D IEI010646 Protein protein interactors of human gene PSMD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD1 (SwissProt ID= (more detail) 129 17535438 Homo sapiens

I2D IEI003704 Protein protein interactors of human gene DNMT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNMT1 (SwissProt ID= (more detail) 86 17535438 Homo sapiens

I2D TAX032209 GO:1901653 biological process cellular response to peptide Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 201 NA Homo sapiens

GOA MAX002339 Genes constituting the BRCA centered network (BCN). Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms (more detail) 113 NA Homo sapiens

MSigDB TAX014421 GO:0002758 biological process innate immune response activating signal transduction The cascade of processes by which a signal interacts with a receptor, causing a change in the level (more detail) 169 NA Homo sapiens

GOA TAX022553 GO:0034599 biological process cellular response to oxidative stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 189 NA Homo sapiens

GOA IEI002543 Protein protein interactors of human gene CHUK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHUK (SwissProt ID=O (more detail) 177 17535438 Homo sapiens

I2D TAX016778 GO:0007093 biological process mitotic cell cycle checkpoint A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing p (more detail) 96 NA Homo sapiens

GOA TAX035009 GO:2001022 biological process positive regulation of response to DNA damage stimulus Any process that activates or increases the frequency, rate or extent of response to DNA damage stim (more detail) 83 NA Homo sapiens

GOA WIG001026 Genes involved in NGF signalling via TRKA from the plasma membrane (more detail) 133 NA Homo sapiens

MSigDB FOX000145 Neighborhood of HDAC1 Neighborhood of HDAC1 histone deacetylase 1 in the GNF2 expression compendium (more detail) 108 NA Homo sapiens

MSigDB FEX009446 hsa miR 335 5p HITS-CLIP, Functional MTI (Weak) (more detail) 2439 NA Homo sapiens

mirTARbase IEI007770 Protein protein interactors of human gene MBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MBP (SwissProt ID=P0 (more detail) 80 17535438 Homo sapiens

I2D TAX001428 Genes annotated by the GO term GO:0016758. Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). (more detail) 80 NA Homo sapiens

MSigDB TAX033898 GO:1905368 cellular component peptidase complex A protein complex which is capable of peptidase activity. (more detail) 88 NA Homo sapiens

GOA TAX030084 GO:0072599 biological process establishment of protein localization to endoplasmic reticulum The directed movement of a protein to a specific location in the endoplasmic reticulum. (more detail) 103 NA Homo sapiens

GOA WAG000874 APC/C:Cdc20 mediated degradation of Securin (more detail) 57 NA Homo sapiens

Reactome TAX022277 GO:0034033 biological process purine nucleoside bisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, (more detail) 57 NA Homo sapiens

GOA TAX022250 GO:0033866 biological process nucleoside bisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compo (more detail) 57 NA Homo sapiens

GOA TAX021607 GO:0032508 biological process DNA duplex unwinding The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', ge (more detail) 57 NA Homo sapiens

GOA TAX019472 GO:0018149 biological process peptide cross linking The formation of a covalent cross-link between or within protein chains. (more detail) 57 NA Homo sapiens

GOA TAX022274 GO:0034030 biological process ribonucleoside bisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a c (more detail) 57 NA Homo sapiens

GOA TAX000536 Genes annotated by the GO term GO:0006470. The process of removing one or more phosphoric residues from a protein. (more detail) 61 NA Homo sapiens

MSigDB IEI008787 Protein protein interactors of human gene NFE2L2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFE2L2 (SwissProt ID (more detail) 71 17535438 Homo sapiens

I2D TAX025353 GO:0045931 biological process positive regulation of mitotic cell cycle Any process that activates or increases the rate or extent of progression through the mitotic cell c (more detail) 141 NA Homo sapiens

GOA FEX005590 GSE2405 0H VS 9H A PHAGOCYTOPHILUM STIM NEUTROPHIL DN Gene sets that represent cell states and perturbations within the immune system for GSE2405_0H_VS_9H (more detail) 186 26795250 Homo sapiens

MSigDB TAX029691 GO:0071824 biological process protein DNA complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the forma (more detail) 186 NA Homo sapiens

GOA FOX000366 Neighborhood of PRKDC Neighborhood of PRKDC protein kinase, DNA-activated, catalytic polypeptide in the MORF expression c (more detail) 176 NA Homo sapiens

MSigDB TAX027185 GO:0051783 biological process regulation of nuclear division Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of th (more detail) 184 NA Homo sapiens

GOA MOX017572 Genes associated with Computational Drug Signature Velcade(Bortezomib) Genes associated with Computational Drug Signature Velcade(Bortezomib), curated by the Drug Signatur (more detail) 178 25990557 Homo sapiens

DSigDB IEI005927 Protein protein interactors of human gene HNRNPA0 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPA0 (SwissProt I (more detail) 147 17535438 Homo sapiens

I2D FOX000342 Neighborhood of NME2 Neighborhood of NME2 non-metastatic cells 2, protein (NM23B) expressed in in the MORF expression co (more detail) 147 NA Homo sapiens

MSigDB IEI010651 Protein protein interactors of human gene PSMD14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD14 (SwissProt ID (more detail) 90 17535438 Homo sapiens

I2D IEI006972 Protein protein interactors of human gene KMT2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KMT2A (SwissProt ID= (more detail) 95 17535438 Homo sapiens

I2D WIG000169 Regulation of nuclear SMAD2/3 signaling (more detail) 82 NA Homo sapiens

MSigDB MEX002134 Genes associated with Kinase Inhibitor BRD K83972459 001 01 9 Genes associated with Kinase Inhibitor BRD-K83972459-001-01-9, curated by the Drug Signature Databas (more detail) 64 25990557 Homo sapiens

DSigDB IEI013002 Protein protein interactors of human gene SRSF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF7 (SwissProt ID= (more detail) 136 17535438 Homo sapiens

I2D IEI010704 Protein protein interactors of human gene PTGES3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTGES3 (SwissProt ID (more detail) 102 17535438 Homo sapiens

I2D WAG000273 Cap dependent Translation Initiation (more detail) 102 NA Homo sapiens

Reactome TAX021549 GO:0032436 biological process positive regulation of proteasomal ubiquitin dependent protein catabolic process Any process that activates or increases the frequency, rate or extent of the breakdown of a protein (more detail) 87 NA Homo sapiens

GOA IEI014784 Protein protein interactors of human gene USP39 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP39 (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D TAX029959 GO:0072330 biological process monocarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic (more detail) 197 NA Homo sapiens

GOA TAX022730 GO:0035097 cellular component histone methyltransferase complex A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins. (more detail) 67 NA Homo sapiens

GOA IEI010294 Protein protein interactors of human gene PPARGC1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPARGC1A (SwissProt (more detail) 67 17535438 Homo sapiens

I2D IEI014475 Protein protein interactors of human gene TUBB4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TUBB4B (SwissProt ID (more detail) 189 17535438 Homo sapiens

I2D TAX023489 GO:0038093 biological process Fc receptor signaling pathway A series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an (more detail) 187 NA Homo sapiens

GOA MAX003008 DNA repair genes whose promoters contain putative ZNF143 [GeneID=7702] binding sites. Zinc-finger protein 143 (ZNF143) is a human homolog of Xenopus transcriptional activator staf that i (more detail) 56 NA Homo sapiens

MSigDB MEX001357 Genes associated with Kinase Inhibitor BX 795 Genes associated with Kinase Inhibitor BX-795, curated by the Drug Signature Database (DSigDB). (more detail) 56 25990557 Homo sapiens

DSigDB WAG000275 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (more detail) 56 NA Homo sapiens

Reactome TAX001065 Genes annotated by the GO term GO:0016881. Catalysis of the ligation of an acid to an amino acid via a carbon nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. (more detail) 56 NA Homo sapiens

MSigDB WAG001078 Autodegradation of Cdh1 by Cdh1:APC/C (more detail) 56 NA Homo sapiens

Reactome TAX015116 GO:0004402 molecular function histone acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone. (more detail) 56 NA Homo sapiens

GOA TAX016162 GO:0006165 biological process nucleoside diphosphate phosphorylation The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside t (more detail) 56 NA Homo sapiens

GOA IEI002261 Protein protein interactors of human gene CDK6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK6 (SwissProt ID=Q (more detail) 118 17535438 Homo sapiens

I2D TAX015872 GO:0005684 cellular component U2 type spliceosomal complex Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to exc (more detail) 70 NA Homo sapiens

GOA TAX026789 GO:0051092 biological process positive regulation of NF kappaB transcription factor activity Any process that activates or increases the frequency, rate or extent of activity of the transcripti (more detail) 144 NA Homo sapiens

GOA IEI013993 Protein protein interactors of human gene TNF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNF (SwissProt ID=P0 (more detail) 111 17535438 Homo sapiens

I2D IEI013358 Protein protein interactors of human gene TAF9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF9 (SwissProt ID=Q (more detail) 94 17535438 Homo sapiens

I2D IEI014117 Protein protein interactors of human gene TP73 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TP73 (SwissProt ID=O (more detail) 122 17535438 Homo sapiens

I2D IEI010643 Protein protein interactors of human gene PSMC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMC4 (SwissProt ID= (more detail) 122 17535438 Homo sapiens

I2D TAX020966 GO:0031398 biological process positive regulation of protein ubiquitination Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin g (more detail) 106 NA Homo sapiens

GOA IEI010657 Protein protein interactors of human gene PSMD7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD7 (SwissProt ID= (more detail) 81 17535438 Homo sapiens

I2D TAX000880 Genes annotated by the GO term GO:0016591. Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre mRNA. (more detail) 63 NA Homo sapiens

MSigDB TAX020294 GO:0030099 biological process myeloid cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized feat (more detail) 160 NA Homo sapiens

GOA WIG001588 NFAT and Cardiac Hypertrophy NFAT and Cardiac Hypertrophy (more detail) 115 NA Homo sapiens

Protein Lounge IEI010540 Protein protein interactors of human gene PRPF40A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRPF40A (SwissProt I (more detail) 162 17535438 Homo sapiens

I2D WIG001072 Genes involved in Phospholipid metabolism (more detail) 186 NA Homo sapiens

MSigDB IEI008081 Protein protein interactors of human gene MNDA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MNDA (SwissProt ID=P (more detail) 166 17535438 Homo sapiens

I2D WAG000187 Prostate cancer Prostate cancer constitutes a major health problem in Western countries. It is the most frequently d (more detail) 78 NA Homo sapiens

KEGG IEI012589 Protein protein interactors of human gene SMARCA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCA2 (SwissProt I (more detail) 108 17535438 Homo sapiens

I2D IEI005577 Protein protein interactors of human gene GTF2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2B (SwissProt ID= (more detail) 86 17535438 Homo sapiens

I2D IEI010625 Protein protein interactors of human gene PSMA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMA5 (SwissProt ID= (more detail) 126 17535438 Homo sapiens

I2D WIG000809 Genes involved in Downstream signaling of activated FGFR (more detail) 96 NA Homo sapiens

MSigDB IEI009075 Protein protein interactors of human gene NSD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NSD2 (SwissProt ID=O (more detail) 141 17535438 Homo sapiens

I2D IEI007645 Protein protein interactors of human gene MAP2K1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP2K1 (SwissProt ID (more detail) 91 17535438 Homo sapiens

I2D TAX028215 GO:0060968 biological process regulation of gene silencing Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or (more detail) 75 NA Homo sapiens

GOA WIG001047 Genes involved in Orc1 removal from chromatin (more detail) 66 NA Homo sapiens

MSigDB TAX020197 GO:0022625 cellular component cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol. (more detail) 66 NA Homo sapiens

GOA TAX024657 GO:0044273 biological process sulfur compound catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, suc (more detail) 55 NA Homo sapiens

GOA TAX019494 GO:0018208 biological process peptidyl proline modification The modification of peptidyl-proline. (more detail) 55 NA Homo sapiens

GOA MEX001456 Genes associated with Kinase Inhibitor Vandetanib Genes associated with Kinase Inhibitor Vandetanib, curated by the Drug Signature Database (DSigDB). (more detail) 55 25990557 Homo sapiens

DSigDB MEX002395 Genes associated with Kinase Inhibitor Vandetanib Genes associated with Kinase Inhibitor Vandetanib, curated by the Drug Signature Database (DSigDB). (more detail) 55 25990557 Homo sapiens

DSigDB WAG000741 Viral Messenger RNA Synthesis (more detail) 55 NA Homo sapiens

Reactome MEX002061 Genes associated with Kinase Inhibitor 878739 06 1 Genes associated with Kinase Inhibitor 878739-06-1, curated by the Drug Signature Database (DSigDB). (more detail) 55 25990557 Homo sapiens

DSigDB MEX002358 Genes associated with Kinase Inhibitor JAK3 Inhibitor VI Genes associated with Kinase Inhibitor JAK3 Inhibitor VI, curated by the Drug Signature Database (DS (more detail) 55 25990557 Homo sapiens

DSigDB MEX001371 Genes associated with Kinase Inhibitor Sorafenib Genes associated with Kinase Inhibitor Sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 55 25990557 Homo sapiens

DSigDB WAG000684 GTP hydrolysis and joining of the 60S ribosomal subunit (more detail) 103 NA Homo sapiens

Reactome IEI002262 Protein protein interactors of human gene CDK7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK7 (SwissProt ID=P (more detail) 72 17535438 Homo sapiens

I2D IEI001355 Protein protein interactors of human gene BLM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BLM (SwissProt ID=P5 (more detail) 72 17535438 Homo sapiens

I2D TAX023902 GO:0042571 cellular component immunoglobulin complex, circulating An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or ot (more detail) 59 NA Homo sapiens

GOA IEI002471 Protein protein interactors of human gene CHEK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHEK1 (SwissProt ID= (more detail) 83 17535438 Homo sapiens

I2D FOX000235 Neighborhood of AATF Neighborhood of AATF apoptosis antagonizing transcription factor in the MORF expression compendium (more detail) 197 NA Homo sapiens

MSigDB IEI013092 Protein protein interactors of human gene STAT5A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAT5A (SwissProt ID (more detail) 112 17535438 Homo sapiens

I2D TAX000242 Genes annotated by the GO term GO:0009100. The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues other than as a moiety of nucleic acid; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. (more detail) 88 NA Homo sapiens

MSigDB IEI011500 Protein protein interactors of human gene RPL10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL10 (SwissProt ID= (more detail) 93 17535438 Homo sapiens

I2D IEI001346 Protein protein interactors of human gene BIRC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BIRC3 (SwissProt ID= (more detail) 93 17535438 Homo sapiens

I2D IEI003066 Protein protein interactors of human gene CSNK2A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSNK2A2 (SwissProt I (more detail) 189 17535438 Homo sapiens

I2D IEI014088 Protein protein interactors of human gene TOP2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TOP2A (SwissProt ID= (more detail) 80 17535438 Homo sapiens

I2D TAX018795 GO:0015934 cellular component large ribosomal subunit The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved (more detail) 123 NA Homo sapiens

GOA IEI011502 Protein protein interactors of human gene RPL10L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL10L (SwissProt ID (more detail) 100 17535438 Homo sapiens

I2D WIG001208 Genes involved in Signaling by Interleukins (more detail) 107 NA Homo sapiens

MSigDB MEX001850 Genes associated with Kinase Inhibitor AGN PC 0D0DBW Genes associated with Kinase Inhibitor AGN-PC-0D0DBW, curated by the Drug Signature Database (DSigDB (more detail) 62 25990557 Homo sapiens

DSigDB IEI010218 Protein protein interactors of human gene POLR2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2B (SwissProt ID (more detail) 90 17535438 Homo sapiens

I2D IEI010937 Protein protein interactors of human gene RAD23B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD23B (SwissProt ID (more detail) 90 17535438 Homo sapiens

I2D TAX022174 GO:0033613 molecular function activating transcription factor binding Interacting selectively and non-covalently with an activating transcription factor, any protein whos (more detail) 65 NA Homo sapiens

GOA WIG000074 Signaling events mediated by HDAC Class I (more detail) 65 NA Homo sapiens

MSigDB TAX013302 GO:0000187 biological process activation of MAPK activity The initiation of the activity of the inactive enzyme MAP kinase (MAPK). (more detail) 148 NA Homo sapiens

GOA TAX017482 GO:0009066 biological process aspartate family amino acid metabolic process The chemical reactions and pathways involving amino acids of the aspartate family, comprising aspara (more detail) 54 NA Homo sapiens

GOA TAX030039 GO:0072528 biological process pyrimidine containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, (more detail) 54 NA Homo sapiens

GOA TAX021931 GO:0033013 biological process tetrapyrrole metabolic process The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrol (more detail) 54 NA Homo sapiens

GOA MEX002381 Genes associated with Kinase Inhibitor Neratinib Genes associated with Kinase Inhibitor Neratinib, curated by the Drug Signature Database (DSigDB). (more detail) 54 25990557 Homo sapiens

DSigDB TAX000093 Genes annotated by the GO term GO:0044257. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. (more detail) 54 NA Homo sapiens

MSigDB MEX001204 Genes associated with Kinase Inhibitor Ro 31 8220 mesylate Genes associated with Kinase Inhibitor Ro 31-8220 mesylate, curated by the Drug Signature Database ( (more detail) 54 25990557 Homo sapiens

DSigDB TAX001268 Genes annotated by the GO term GO:0004518. Catalysis of the hydrolysis of ester linkages within nucleic acids. (more detail) 54 NA Homo sapiens

MSigDB MEX002129 Genes associated with Kinase Inhibitor Flavopiridol Genes associated with Kinase Inhibitor Flavopiridol, curated by the Drug Signature Database (DSigDB) (more detail) 58 25990557 Homo sapiens

DSigDB TAX016224 GO:0006275 biological process regulation of DNA replication Any process that modulates the frequency, rate or extent of DNA replication. (more detail) 97 NA Homo sapiens

GOA IEI002078 Protein protein interactors of human gene CCT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCT3 (SwissProt ID=P (more detail) 188 17535438 Homo sapiens

I2D IEI007794 Protein protein interactors of human gene MCM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCM2 (SwissProt ID=P (more detail) 111 17535438 Homo sapiens

I2D MAX003120 Genes periodically expressed in synchronized HeLa cells (cervical carcinoma), with peak during the G1/S phase of cell cycle. The genome-wide program of gene expression during the cell division cycle in a human cancer cell lin (more detail) 133 NA Homo sapiens

MSigDB MOX004683 Genes associated with Computational Drug Signature 17 Hydroxyandrostan 3 one Genes associated with Computational Drug Signature 17-Hydroxyandrostan-3-one, curated by the Drug Si (more detail) 182 25990557 Homo sapiens

DSigDB IEI008637 Protein protein interactors of human gene NCOA6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCOA6 (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D IEI003405 Protein protein interactors of human gene DDX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX1 (SwissProt ID=Q (more detail) 164 17535438 Homo sapiens

I2D FAX001243 Genes up regulated in comparison of polysome bound (translated) mRNA versus total mRNA 4 h after LPS (TLR4 agonist) stimulation. Dendritic cells (DCs) are the sentinels of the mammalian immune system and they undergo a complex ma (more detail) 176 NA Homo sapiens

MSigDB FEX003731 GSE14000 TRANSLATED RNA VS MRNA 4H LPS DC UP Gene sets that represent cell states and perturbations within the immune system for GSE14000_TRANSLA (more detail) 174 26795250 Homo sapiens

MSigDB IEI014107 Protein protein interactors of human gene TP53BP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TP53BP1 (SwissProt I (more detail) 135 17535438 Homo sapiens

I2D IEI000522 Protein protein interactors of human gene ALYREF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ALYREF (SwissProt ID (more detail) 135 17535438 Homo sapiens

I2D FEX002814 StemCell Manalo05 108genes Table 2. Selected genes repressed by both hypoxia and AdCA5 (more detail) 79 15374877 Homo sapiens

GeneSigDB IEI005483 Protein protein interactors of human gene GRB7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRB7 (SwissProt ID=Q (more detail) 139 17535438 Homo sapiens

I2D MOX017758 Genes associated with Computational Drug Signature Dasatinib Genes associated with Computational Drug Signature Dasatinib, curated by the Drug Signature Database (more detail) 106 25990557 Homo sapiens

DSigDB FOX000007 Neighborhood of ACTG1 Neighborhood of ACTG1 actin, gamma 1 in the GCM expression compendium (more detail) 115 NA Homo sapiens

MSigDB IEI011203 Protein protein interactors of human gene RFC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RFC4 (SwissProt ID=P (more detail) 84 17535438 Homo sapiens

I2D TAX016472 GO:0006613 biological process cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation. The transport of most secret (more detail) 94 NA Homo sapiens

GOA IEI014237 Protein protein interactors of human gene TRIM33 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM33 (SwissProt ID (more detail) 76 17535438 Homo sapiens

I2D IEI008409 Protein protein interactors of human gene MYB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYB (SwissProt ID=P1 (more detail) 89 17535438 Homo sapiens

I2D IEI011708 Protein protein interactors of human gene RUNX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RUNX2 (SwissProt ID= (more detail) 64 17535438 Homo sapiens

I2D TAX000523 Genes annotated by the GO term GO:0045944. Any process that activates or increases the frequency, rate or extent of transcription from the RNA polymerase II promoter. (more detail) 64 NA Homo sapiens

MSigDB WIG000713 Genes involved in Assembly of the pre replicative complex (more detail) 64 NA Homo sapiens

MSigDB IEI010971 Protein protein interactors of human gene RALY from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RALY (SwissProt ID=Q (more detail) 70 17535438 Homo sapiens

I2D TAX029220 GO:0070972 biological process protein localization to endoplasmic reticulum A process in which a protein is transported to, or maintained in, a location within the endoplasmic (more detail) 110 NA Homo sapiens

GOA WIG001211 Genes involved in Signaling by NOTCH (more detail) 96 NA Homo sapiens

MSigDB MEX001227 Genes associated with Kinase Inhibitor 718630 59 2 Genes associated with Kinase Inhibitor 718630-59-2, curated by the Drug Signature Database (DSigDB). (more detail) 53 25990557 Homo sapiens

DSigDB TAX016242 GO:0006301 biological process postreplication repair The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after repl (more detail) 53 NA Homo sapiens

GOA IEI012083 Protein protein interactors of human gene SF3B2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SF3B2 (SwissProt ID= (more detail) 103 17535438 Homo sapiens

I2D TAX021370 GO:0032182 molecular function ubiquitin like protein binding Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a u (more detail) 86 NA Homo sapiens

GOA TAX019562 GO:0018958 biological process phenol containing compound metabolic process The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl (more detail) 78 NA Homo sapiens

GOA WIG001818 DNA damage induced G1 S checkpointÃƒâ€šÃ‚Â DNA damage activates Ataxia telangiectasia mutated (ATM) and/or ATM and Rad3-related (ATR) signaling (more detail) 78 NA Homo sapiens

Spike IEI011594 Protein protein interactors of human gene RPS28 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS28 (SwissProt ID= (more detail) 114 17535438 Homo sapiens

I2D IEI002181 Protein protein interactors of human gene CDC27 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC27 (SwissProt ID= (more detail) 88 17535438 Homo sapiens

I2D TAX034573 GO:2000278 biological process regulation of DNA biosynthetic process Any process that modulates the frequency, rate or extent of DNA biosynthetic process. (more detail) 107 NA Homo sapiens

GOA TAX029234 GO:0070988 biological process demethylation The process of removing one or more methyl groups from a molecule. (more detail) 60 NA Homo sapiens

GOA MOX017249 Genes associated with Computational Drug Signature ellagic acid Genes associated with Computational Drug Signature ellagic acid, curated by the Drug Signature Datab (more detail) 180 25990557 Homo sapiens

DSigDB IEI009991 Protein protein interactors of human gene PKM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PKM (SwissProt ID=P1 (more detail) 176 17535438 Homo sapiens

I2D IEI001080 Protein protein interactors of human gene ATP5F1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP5F1A (SwissProt I (more detail) 168 17535438 Homo sapiens

I2D IEI002472 Protein protein interactors of human gene CHEK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHEK2 (SwissProt ID= (more detail) 95 17535438 Homo sapiens

I2D WIG000667 Genes involved in Activation of NF kappaB in B Cells (more detail) 63 NA Homo sapiens

MSigDB WIG000780 Genes involved in Cyclin E associated events during G1/S transition (more detail) 63 NA Homo sapiens

MSigDB TAX022684 GO:0034987 molecular function immunoglobulin receptor binding Interacting selectively and non-covalently with one or more specific sites on an immunoglobulin rece (more detail) 63 NA Homo sapiens

GOA PEX001513 RRM 1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) The RRM motif is probably diagnostic of an RNA binding protein. RRMs are found in a variety of RNA b (more detail) 102 NA Homo sapiens

Pfam TAX019352 GO:0017053 cellular component transcriptional repressor complex A protein complex that possesses activity that prevents or downregulates transcription. (more detail) 85 NA Homo sapiens

GOA IEI005931 Protein protein interactors of human gene HNRNPA3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPA3 (SwissProt I (more detail) 122 17535438 Homo sapiens

I2D TAX019276 GO:0016879 molecular function ligase activity, forming carbon nitrogen bonds Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitr (more detail) 52 NA Homo sapiens

GOA TAX024598 GO:0044106 biological process cellular amine metabolic process The chemical reactions and pathways involving any organic compound that is weakly basic in character (more detail) 52 NA Homo sapiens

GOA TAX017690 GO:0009435 biological process NAD biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, (more detail) 52 NA Homo sapiens

GOA MEX002048 Genes associated with Kinase Inhibitor 1,9 Pyrazoloanthrone Genes associated with Kinase Inhibitor 1,9-Pyrazoloanthrone, curated by the Drug Signature Database (more detail) 52 25990557 Homo sapiens

DSigDB WIG001824 Mismatch repair (MMR) Mismatch repair (MMR) is a system for recognizing and repairing erroneous insertions/deletions loops (more detail) 52 NA Homo sapiens

Spike IEI007852 Protein protein interactors of human gene MED23 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED23 (SwissProt ID= (more detail) 56 17535438 Homo sapiens

I2D IEI007853 Protein protein interactors of human gene MED24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED24 (SwissProt ID= (more detail) 56 17535438 Homo sapiens

I2D WIG001198 Genes involved in Signaling by ERBB2 (more detail) 97 NA Homo sapiens

MSigDB IEI005949 Protein protein interactors of human gene HNRNPUL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPUL1 (SwissProt (more detail) 177 17535438 Homo sapiens

I2D WIG000658 Genes involved in Activated TLR4 signalling (more detail) 92 NA Homo sapiens

MSigDB IEI002850 Protein protein interactors of human gene COPS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COPS2 (SwissProt ID= (more detail) 92 17535438 Homo sapiens

I2D TAX023987 GO:0042737 biological process drug catabolic process The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the di (more detail) 115 NA Homo sapiens

GOA TAX000449 Genes annotated by the GO term GO:0006082. The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. (more detail) 173 NA Homo sapiens

MSigDB TAX026796 GO:0051099 biological process positive regulation of binding Any process that activates or increases the rate or extent of binding, the selective interaction of (more detail) 169 NA Homo sapiens

GOA IEI002084 Protein protein interactors of human gene CCT8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCT8 (SwissProt ID=P (more detail) 167 17535438 Homo sapiens

I2D IEI002033 Protein protein interactors of human gene CCNA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNA2 (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D IEI010939 Protein protein interactors of human gene RAD51 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD51 (SwissProt ID= (more detail) 99 17535438 Homo sapiens

I2D IEI007846 Protein protein interactors of human gene MED17 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED17 (SwissProt ID= (more detail) 59 17535438 Homo sapiens

I2D MOX003562 Genes associated with Computational Drug Signature PONATINIB Genes associated with Computational Drug Signature PONATINIB, curated by the Drug Signature Database (more detail) 59 25990557 Homo sapiens

DSigDB WIG001174 Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription (more detail) 59 NA Homo sapiens

MSigDB TAX001238 Genes annotated by the GO term GO:0000287. Interacting selectively with magnesium (Mg) ions. (more detail) 59 NA Homo sapiens

MSigDB IEI011057 Protein protein interactors of human gene RBCK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBCK1 (SwissProt ID= (more detail) 71 17535438 Homo sapiens

I2D MOX012883 Genes associated with Computational Drug Signature GNF Pf 2272 Genes associated with Computational Drug Signature GNF-Pf-2272, curated by the Drug Signature Databa (more detail) 94 25990557 Homo sapiens

DSigDB TAX031660 GO:0120114 cellular component Sm like protein family complex A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm p (more detail) 79 NA Homo sapiens

GOA TAX019827 GO:0019814 cellular component immunoglobulin complex A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chain (more detail) 62 NA Homo sapiens

GOA IEI012601 Protein protein interactors of human gene SMC1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMC1A (SwissProt ID= (more detail) 110 17535438 Homo sapiens

I2D IEI007196 Protein protein interactors of human gene LDHA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LDHA (SwissProt ID=P (more detail) 110 17535438 Homo sapiens

I2D TAX026632 GO:0050853 biological process B cell receptor signaling pathway A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell. (more detail) 89 NA Homo sapiens

GOA WAG000696 Orc1 removal from chromatin (more detail) 55 NA Homo sapiens

Reactome TAX030034 GO:0072523 biological process purine containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. (more detail) 51 NA Homo sapiens

GOA TAX017249 GO:0008408 molecular function 3' 5' exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues f (more detail) 51 NA Homo sapiens

GOA TAX015340 GO:0004715 molecular function non membrane spanning protein tyrosine kinase activity Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-me (more detail) 51 NA Homo sapiens

GOA TAX013467 GO:0000726 biological process non recombinational repair A DNA repair process in which that does not require the exchange of genetic material between the bro (more detail) 51 NA Homo sapiens

GOA WIG001446 Chks in Checkpoint Regulation Chks in Checkpoint Regulation (more detail) 51 NA Homo sapiens

Protein Lounge TAX016244 GO:0006303 biological process double strand break repair via nonhomologous end joining The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or (more detail) 51 NA Homo sapiens

GOA TAX001387 Genes annotated by the GO term GO:0008639. Catalysis of the covalent attachment of small proteins, such as ubiquitin or ubiquitin like proteins, to lysine residues on a target protein. This function may be performed alone or in conjunction with an E3, ubiquitin like protein ligase. (more detail) 51 NA Homo sapiens

MSigDB TAX016442 GO:0006576 biological process cellular biogenic amine metabolic process The chemical reactions and pathways occurring at the level of individual cells involving any of a gr (more detail) 51 NA Homo sapiens

GOA TAX001402 Genes annotated by the GO term GO:0043566. Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. (more detail) 51 NA Homo sapiens

MSigDB TAX016083 GO:0006029 biological process proteoglycan metabolic process The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydr (more detail) 51 NA Homo sapiens

GOA WIG001280 Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (more detail) 76 NA Homo sapiens

MSigDB TAX024366 GO:0043433 biological process negative regulation of DNA binding transcription factor activity Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a tran (more detail) 152 NA Homo sapiens

GOA IEI012060 Protein protein interactors of human gene SET from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SET (SwissProt ID=Q0 (more detail) 152 17535438 Homo sapiens

I2D IEI008952 Protein protein interactors of human gene NOS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOS2 (SwissProt ID=P (more detail) 168 17535438 Homo sapiens

I2D IEI002081 Protein protein interactors of human gene CCT6A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCT6A (SwissProt ID= (more detail) 156 17535438 Homo sapiens

I2D TAX016775 GO:0007088 biological process regulation of mitotic nuclear division Any process that modulates the frequency, rate or extent of mitosis. (more detail) 162 NA Homo sapiens

GOA IEI010534 Protein protein interactors of human gene PRPF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRPF3 (SwissProt ID= (more detail) 81 17535438 Homo sapiens

I2D IEI010984 Protein protein interactors of human gene RANBP9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RANBP9 (SwissProt ID (more detail) 116 17535438 Homo sapiens

I2D IEI007865 Protein protein interactors of human gene MED9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED9 (SwissProt ID=Q (more detail) 73 17535438 Homo sapiens

I2D WIG001306 Genes involved in TRIF mediated TLR3 signaling (more detail) 73 NA Homo sapiens

MSigDB WIG000716 Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C (more detail) 58 NA Homo sapiens

MSigDB TAX018841 GO:0016051 biological process carbohydrate biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of o (more detail) 120 NA Homo sapiens

GOA IEI011099 Protein protein interactors of human gene RBM8A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM8A (SwissProt ID= (more detail) 78 17535438 Homo sapiens

I2D IEI010649 Protein protein interactors of human gene PSMD12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD12 (SwissProt ID (more detail) 88 17535438 Homo sapiens

I2D FOX000541 Genes in the cancer module 209 (more detail) 88 NA Homo sapiens

MSigDB WIG000181 Regulation of Telomerase (more detail) 67 NA Homo sapiens

MSigDB TAX013357 GO:0000302 biological process response to reactive oxygen species Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 173 NA Homo sapiens

GOA TAX000069 Genes annotated by the GO term GO:0019752. The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO ). (more detail) 171 NA Homo sapiens

MSigDB IEI010653 Protein protein interactors of human gene PSMD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD3 (SwissProt ID= (more detail) 111 17535438 Homo sapiens

I2D IEI011522 Protein protein interactors of human gene RPL27 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL27 (SwissProt ID= (more detail) 102 17535438 Homo sapiens

I2D WIG001097 Genes involved in PPARA Activates Gene Expression (more detail) 102 NA Homo sapiens

MSigDB TAX013815 GO:0001763 biological process morphogenesis of a branching structure The process in which the anatomical structures of branches are generated and organized. A branch is (more detail) 149 NA Homo sapiens

GOA TAX019259 GO:0016853 molecular function isomerase activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic na (more detail) 151 NA Homo sapiens

GOA IEI001345 Protein protein interactors of human gene BIRC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BIRC2 (SwissProt ID= (more detail) 124 17535438 Homo sapiens

I2D IEI011063 Protein protein interactors of human gene RBL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBL1 (SwissProt ID=P (more detail) 95 17535438 Homo sapiens

I2D WIG001490 Estrogen Pathway Estrogen Pathway (more detail) 113 NA Homo sapiens

Protein Lounge IEI009821 Protein protein interactors of human gene PGR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PGR (SwissProt ID=P0 (more detail) 75 17535438 Homo sapiens

I2D TAX026852 GO:0051179 biological process localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organel (more detail) 4590 NA Homo sapiens

GOA TAX024547 GO:0043967 biological process histone H4 acetylation The modification of histone H4 by the addition of an acetyl group. (more detail) 50 NA Homo sapiens

GOA TAX014756 GO:0003678 molecular function DNA helicase activity Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix. (more detail) 50 NA Homo sapiens

GOA TAX019223 GO:0016796 molecular function exonuclease activity, active with either ribo or deoxyribonucleic acids and producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues f (more detail) 50 NA Homo sapiens

GOA TAX001129 Genes annotated by the GO term GO:0008234. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides; a cysteine residue is at the active center. (more detail) 50 NA Homo sapiens

MSigDB MEX002421 Genes associated with Kinase Inhibitor Cabozantinib Genes associated with Kinase Inhibitor Cabozantinib, curated by the Drug Signature Database (DSigDB) (more detail) 50 25990557 Homo sapiens

DSigDB TAX013471 GO:0000731 biological process DNA synthesis involved in DNA repair Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous inta (more detail) 50 NA Homo sapiens

GOA TAX001383 Genes annotated by the GO term GO:0019787. Catalysis of ATP dependent isopeptide bond formation between the carboxy terminal residues of a small conjugating protein such as ubiquitin or a ubiquitin like protein, and a substrate lysine residue. (more detail) 50 NA Homo sapiens

MSigDB IEI011376 Protein protein interactors of human gene RNF11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF11 (SwissProt ID= (more detail) 104 17535438 Homo sapiens

I2D IEI010308 Protein protein interactors of human gene PPIA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPIA (SwissProt ID=P (more detail) 128 17535438 Homo sapiens

I2D IEI005651 Protein protein interactors of human gene H2AC20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AC20 (SwissProt ID (more detail) 90 17535438 Homo sapiens

I2D IEI013680 Protein protein interactors of human gene THRA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THRA (SwissProt ID=P (more detail) 90 17535438 Homo sapiens

I2D IEI009855 Protein protein interactors of human gene PHGDH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHGDH (SwissProt ID= (more detail) 130 17535438 Homo sapiens

I2D IEI008490 Protein protein interactors of human gene MYOD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYOD1 (SwissProt ID= (more detail) 80 17535438 Homo sapiens

I2D TAX021917 GO:0032993 cellular component protein DNA complex A macromolecular complex containing both protein and DNA molecules. (more detail) 85 NA Homo sapiens

GOA WIG000597 Progesterone mediated oocyte maturation Xenopus oocytes are naturally arrested at G2 of meiosis I. Exposure to either insulin/IGF-1 or the s (more detail) 85 NA Homo sapiens

MSigDB TAX020622 GO:0030684 cellular component preribosome Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogene (more detail) 72 NA Homo sapiens

GOA IEI010277 Protein protein interactors of human gene POU2F1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POU2F1 (SwissProt ID (more detail) 72 17535438 Homo sapiens

I2D IEI008563 Protein protein interactors of human gene NAP1L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NAP1L1 (SwissProt ID (more detail) 138 17535438 Homo sapiens

I2D IEI005942 Protein protein interactors of human gene HNRNPH3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPH3 (SwissProt I (more detail) 138 17535438 Homo sapiens

I2D TAX032693 GO:1902911 cellular component protein kinase complex A protein complex which is capable of protein kinase activity. (more detail) 99 NA Homo sapiens

GOA IEI014225 Protein protein interactors of human gene TRIM21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM21 (SwissProt ID (more detail) 119 17535438 Homo sapiens

I2D TAX017628 GO:0009247 biological process glycolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-ac (more detail) 57 NA Homo sapiens

GOA WAG001143 Removal of licensing factors from origins (more detail) 57 NA Homo sapiens

Reactome TAX020551 GO:0030532 cellular component small nuclear ribonucleoprotein complex A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus o (more detail) 69 NA Homo sapiens

GOA TAX020545 GO:0030518 biological process intracellular steroid hormone receptor signaling pathway A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor (more detail) 77 NA Homo sapiens

GOA MAX000150 Set 'NOS targets': genes upregulated and identified by ChIP on chip as targets of the transcription factors NANOG , OCT4, and Sox2 [GeneID=79923;5460;6657] (NOS) in human embryonic stem cells. Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear, howev (more detail) 164 NA Homo sapiens

MSigDB WIG001840 Apoptosis Anti Apoptosis Network Apoptosis is a mode of cell death that plays an important role in both pathological and physiologica (more detail) 156 NA Homo sapiens

Spike IEI012604 Protein protein interactors of human gene SMC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMC3 (SwissProt ID=Q (more detail) 110 17535438 Homo sapiens

I2D WIG001006 Genes involved in MyD88:Mal cascade initiated on plasma membrane (more detail) 82 NA Homo sapiens

MSigDB WIG001638 Prolactin Signaling Prolactin Signaling (more detail) 66 NA Homo sapiens

Protein Lounge FOX000455 Genes in the cancer module 124 (more detail) 94 NA Homo sapiens

MSigDB IEI003102 Protein protein interactors of human gene CTBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTBP2 (SwissProt ID= (more detail) 94 17535438 Homo sapiens

I2D IEI010656 Protein protein interactors of human gene PSMD6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD6 (SwissProt ID= (more detail) 94 17535438 Homo sapiens

I2D TAX029960 GO:0072331 biological process signal transduction by p53 class mediator An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or (more detail) 125 NA Homo sapiens

GOA TAX034923 GO:2000779 biological process regulation of double strand break repair Any process that modulates the frequency, rate or extent of double-strand break repair. (more detail) 63 NA Homo sapiens

GOA IEI011168 Protein protein interactors of human gene RELB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RELB (SwissProt ID=Q (more detail) 112 17535438 Homo sapiens

I2D FOX000296 Neighborhood of FBL Neighborhood of FBL fibrillarin in the MORF expression compendium (more detail) 131 NA Homo sapiens

MSigDB PEX000656 Trypsin: Trypsin (more detail) 53 NA Homo sapiens

Pfam MEX001333 Genes associated with Kinase Inhibitor Staurosporine, N Benzoyl Genes associated with Kinase Inhibitor Staurosporine, N-Benzoyl, curated by the Drug Signature Datab (more detail) 49 25990557 Homo sapiens

DSigDB MEX002248 Genes associated with Kinase Inhibitor Go 6976 Genes associated with Kinase Inhibitor Go 6976, curated by the Drug Signature Database (DSigDB). (more detail) 49 25990557 Homo sapiens

DSigDB MAX003161 Genes that comprise the proteasome gene module A major goal of cancer research is to match specific therapies to molecular targets in cancer. Genom (more detail) 49 NA Homo sapiens

MSigDB TAX016191 GO:0006213 biological process pyrimidine nucleoside metabolic process The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic (more detail) 49 NA Homo sapiens

GOA TAX024840 GO:0044774 biological process mitotic DNA integrity checkpoint A mitotic cell cycle process that controls cell cycle progression in response to changes in DNA stru (more detail) 49 NA Homo sapiens

GOA TAX032215 GO:1901659 biological process glycosyl compound biosynthetic process The chemical reactions and pathways resulting in the formation of glycosyl compound. (more detail) 49 NA Homo sapiens

GOA TAX031996 GO:1901068 biological process guanosine containing compound metabolic process The chemical reactions and pathways involving guanosine-containing compounds (guanosines). (more detail) 49 NA Homo sapiens

GOA TAX023482 GO:0038083 biological process peptidyl tyrosine autophosphorylation The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosi (more detail) 49 NA Homo sapiens

GOA TAX000994 Genes annotated by the GO term GO:0005730. A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. (more detail) 116 NA Homo sapiens

MSigDB IEI007748 Protein protein interactors of human gene MATR3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MATR3 (SwissProt ID= (more detail) 135 17535438 Homo sapiens

I2D MOX004144 Genes associated with Computational Drug Signature glutathione Genes associated with Computational Drug Signature glutathione, curated by the Drug Signature Databa (more detail) 135 25990557 Homo sapiens

DSigDB WIG000705 Genes involved in Apoptosis (more detail) 137 NA Homo sapiens

MSigDB IEI001823 Protein protein interactors of human gene CASP7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASP7 (SwissProt ID= (more detail) 98 17535438 Homo sapiens

I2D IEI014569 Protein protein interactors of human gene UBE2D4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2D4 (SwissProt ID (more detail) 98 17535438 Homo sapiens

I2D TAX018994 GO:0016363 cellular component nuclear matrix The dense fibrillar network lying on the inner side of the nuclear membrane. (more detail) 107 NA Homo sapiens

GOA IEI012691 Protein protein interactors of human gene SNRPA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRPA1 (SwissProt ID (more detail) 107 17535438 Homo sapiens

I2D FOX000010 Neighborhood of APEX1 Neighborhood of APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 in the GCM expression com (more detail) 107 NA Homo sapiens

MSigDB IEI010443 Protein protein interactors of human gene PRDX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRDX1 (SwissProt ID= (more detail) 161 17535438 Homo sapiens

I2D TAX000078 Genes annotated by the GO term GO:0044262. The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. (more detail) 122 NA Homo sapiens

MSigDB TAX017019 GO:0008023 cellular component transcription elongation factor complex Any protein complex that interacts with RNA polymerase II to increase (positive transcription elonga (more detail) 56 NA Homo sapiens

GOA IEI014625 Protein protein interactors of human gene UBR5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBR5 (SwissProt ID=O (more detail) 93 17535438 Homo sapiens

I2D TAX024221 GO:0043202 cellular component lysosomal lumen The volume enclosed within the lysosomal membrane. (more detail) 93 NA Homo sapiens

GOA TAX033087 GO:1903707 biological process negative regulation of hemopoiesis Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. (more detail) 130 NA Homo sapiens

GOA TAX019840 GO:0019842 molecular function vitamin binding Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic subs (more detail) 134 NA Homo sapiens

GOA IEI005932 Protein protein interactors of human gene HNRNPAB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPAB (SwissProt I (more detail) 134 17535438 Homo sapiens

I2D IEI005944 Protein protein interactors of human gene HNRNPL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPL (SwissProt ID (more detail) 134 17535438 Homo sapiens

I2D MAX002711 Genes consistently up regulated in HMEC cells (primary mammary epithelium) upon expression of TERT [GeneID=7015] off a retroviral vector. Most somatic cells do not express sufficient amounts of telomerase to maintain a constant telomere l (more detail) 138 NA Homo sapiens

MSigDB WIG001051 Genes involved in O linked glycosylation of mucins (more detail) 52 NA Homo sapiens

MSigDB TAX001342 Genes annotated by the GO term GO:0004725. Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. (more detail) 52 NA Homo sapiens

MSigDB WIG000902 Genes involved in Heparan sulfate/heparin (HS GAG) metabolism (more detail) 52 NA Homo sapiens

MSigDB WIG001170 Genes involved in RNA Polymerase II Pre transcription Events (more detail) 52 NA Homo sapiens

MSigDB TAX028119 GO:0060759 biological process regulation of response to cytokine stimulus Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus. (more detail) 160 NA Homo sapiens

GOA IEI008444 Protein protein interactors of human gene MYH9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYH9 (SwissProt ID=P (more detail) 160 17535438 Homo sapiens

I2D IEI012697 Protein protein interactors of human gene SNRPD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRPD3 (SwissProt ID (more detail) 160 17535438 Homo sapiens

I2D TAX019631 GO:0019205 molecular function nucleobase containing compound kinase activity Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside (more detail) 48 NA Homo sapiens

GOA TAX029196 GO:0070936 biological process protein K48 linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine (more detail) 48 NA Homo sapiens

GOA TAX022591 GO:0034656 biological process nucleobase containing small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small mole (more detail) 48 NA Homo sapiens

GOA TAX001445 Genes annotated by the GO term GO:0004842. Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N ubiquityllysine. (more detail) 48 NA Homo sapiens

MSigDB WIG001147 Genes involved in Regulation of ornithine decarboxylase (ODC) (more detail) 48 NA Homo sapiens

MSigDB IEI012692 Protein protein interactors of human gene SNRPB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRPB (SwissProt ID= (more detail) 148 17535438 Homo sapiens

I2D TAX013910 GO:0001889 biological process liver development The process whose specific outcome is the progression of the liver over time, from its formation to (more detail) 106 NA Homo sapiens

GOA TAX032650 GO:1902807 biological process negative regulation of cell cycle G1/S phase transition Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle G1/S phase t (more detail) 97 NA Homo sapiens

GOA MOX001678 Genes associated with Computational Drug Signature myricetin Genes associated with Computational Drug Signature myricetin, curated by the Drug Signature Database (more detail) 99 25990557 Homo sapiens

DSigDB IEI012676 Protein protein interactors of human gene SND1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SND1 (SwissProt ID=Q (more detail) 85 17535438 Homo sapiens

I2D IEI005638 Protein protein interactors of human gene H1 1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H1-1 (SwissProt ID=Q (more detail) 75 17535438 Homo sapiens

I2D TAX000203 Genes annotated by the GO term GO:0006325. The specification, formation and maintenance of the physical structure of eukaryotic chromatin. (more detail) 75 NA Homo sapiens

MSigDB IEI010629 Protein protein interactors of human gene PSMB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMB1 (SwissProt ID= (more detail) 125 17535438 Homo sapiens

I2D WIG000577 Oocyte meiosis During meiosis, a single round of DNA replication is followed by two rounds of chromosome segregatio (more detail) 110 NA Homo sapiens

MSigDB TAX029303 GO:0071158 biological process positive regulation of cell cycle arrest Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which (more detail) 80 NA Homo sapiens

GOA WEX000092 Senescence The genes related to senescence (cell function) in tumor using next-generation sequencer (NGS) reado (more detail) 127 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas TAX016069 GO:0006006 biological process glucose metabolic process The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dex (more detail) 112 NA Homo sapiens

GOA TAX019639 GO:0019213 molecular function deacetylase activity Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. (more detail) 58 NA Homo sapiens

GOA TAX001368 Genes annotated by the GO term GO:0043565. Interacting selectively with DNA of a specific nucleotide composition, e.g. GC rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. (more detail) 58 NA Homo sapiens

MSigDB IEI012087 Protein protein interactors of human gene SF3B6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SF3B6 (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D IEI009039 Protein protein interactors of human gene NR5A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR5A1 (SwissProt ID= (more detail) 61 17535438 Homo sapiens

I2D TAX034495 GO:2000134 biological process negative regulation of G1/S transition of mitotic cell cycle Any cell cycle regulatory process that prevents the commitment of a cell from G1 to S phase of the m (more detail) 94 NA Homo sapiens

GOA TAX020812 GO:0031099 biological process regeneration The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur vi (more detail) 137 NA Homo sapiens

GOA MOX003882 Genes associated with Computational Drug Signature colchicine Genes associated with Computational Drug Signature colchicine, curated by the Drug Signature Databas (more detail) 137 25990557 Homo sapiens

DSigDB IEI012998 Protein protein interactors of human gene SRSF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF3 (SwissProt ID= (more detail) 139 17535438 Homo sapiens

I2D TAX025172 GO:0045619 biological process regulation of lymphocyte differentiation Any process that modulates the frequency, rate or extent of lymphocyte differentiation. (more detail) 159 NA Homo sapiens

GOA TAX000686 Genes annotated by the GO term GO:0051338. Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. (more detail) 155 NA Homo sapiens

MSigDB IEI011538 Protein protein interactors of human gene RPL38 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL38 (SwissProt ID= (more detail) 153 17535438 Homo sapiens

I2D TAX026223 GO:0048562 biological process embryonic organ morphogenesis Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a sp (more detail) 116 NA Homo sapiens

GOA TAX019627 GO:0019199 molecular function transmembrane receptor protein kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to in (more detail) 77 NA Homo sapiens

GOA TAX026031 GO:0048024 biological process regulation of mRNA splicing, via spliceosome Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechani (more detail) 77 NA Homo sapiens

GOA WEX000068 Myeloid Inflammation The genes related to myeloid inflammation (innate immunity) in immune using next-generation sequence (more detail) 96 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI013603 Protein protein interactors of human gene TFAP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TFAP4 (SwissProt ID= (more detail) 89 17535438 Homo sapiens

I2D TAX001038 Genes annotated by the GO term GO:0005681. A ribonucleoprotein complex, containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron. (more detail) 51 NA Homo sapiens

MSigDB TAX001182 Genes annotated by the GO term GO:0004386. Catalysis of the unwinding of a DNA or RNA duplex. (more detail) 51 NA Homo sapiens

MSigDB FEX001656 Leukemia Tavolaro10 56genes Table 3. PK genes highly and specifically expressed in CLL. (more detail) 51 20036005 Homo sapiens

GeneSigDB IEI004767 Protein protein interactors of human gene FHL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FHL2 (SwissProt ID=Q (more detail) 120 17535438 Homo sapiens

I2D MEX001248 Genes associated with Kinase Inhibitor Ro 3306 Genes associated with Kinase Inhibitor Ro-3306, curated by the Drug Signature Database (DSigDB). (more detail) 47 25990557 Homo sapiens

DSigDB TAX014114 GO:0002200 biological process somatic diversification of immune receptors The somatic process allowing for the production of immune receptors whose specificity is not encoded (more detail) 47 NA Homo sapiens

GOA MEX001345 Genes associated with Kinase Inhibitor GSK690693 Genes associated with Kinase Inhibitor GSK690693, curated by the Drug Signature Database (DSigDB). (more detail) 47 25990557 Homo sapiens

DSigDB WIG001036 Genes involved in Nuclear Receptor transcription pathway (more detail) 47 NA Homo sapiens

MSigDB WAG000922 Switching of origins to a post replicative state (more detail) 47 NA Homo sapiens

Reactome WIG000754 Genes involved in Chondroitin sulfate/dermatan sulfate metabolism (more detail) 47 NA Homo sapiens

MSigDB TAX025401 GO:0046031 biological process ADP metabolic process The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate. (more detail) 47 NA Homo sapiens

GOA TAX017560 GO:0009163 biological process nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any one of a family of organic mol (more detail) 47 NA Homo sapiens

GOA TAX016868 GO:0007254 biological process JNK cascade An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a J (more detail) 47 NA Homo sapiens

GOA TAX023325 GO:0036297 biological process interstrand cross link repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of th (more detail) 47 NA Homo sapiens

GOA TAX019447 GO:0018024 molecular function histone lysine N methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + (more detail) 47 NA Homo sapiens

GOA IEI013682 Protein protein interactors of human gene THRB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THRB (SwissProt ID=P (more detail) 69 17535438 Homo sapiens

I2D IEI004228 Protein protein interactors of human gene EPRS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPRS1 (SwissProt ID= (more detail) 124 17535438 Homo sapiens

I2D TAX015964 GO:0005840 cellular component ribosome An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site o (more detail) 109 NA Homo sapiens

GOA IEI005941 Protein protein interactors of human gene HNRNPH2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPH2 (SwissProt I (more detail) 109 17535438 Homo sapiens

I2D IEI000532 Protein protein interactors of human gene AMFR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AMFR (SwissProt ID=Q (more detail) 109 17535438 Homo sapiens

I2D TAX032282 GO:1901861 biological process regulation of muscle tissue development Any process that modulates the frequency, rate or extent of muscle tissue development. (more detail) 126 NA Homo sapiens

GOA TAX021995 GO:0033143 biological process regulation of intracellular steroid hormone receptor signaling pathway Any process that modulates the frequency, rate or extent of the activity of any intracellular steroi (more detail) 74 NA Homo sapiens

GOA IEI014756 Protein protein interactors of human gene USP15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP15 (SwissProt ID= (more detail) 128 17535438 Homo sapiens

I2D TAX026255 GO:0048634 biological process regulation of muscle organ development Any process that modulates the frequency, rate or extent of muscle development. (more detail) 128 NA Homo sapiens

GOA TAX020468 GO:0030330 biological process DNA damage response, signal transduction by p53 class mediator A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent prot (more detail) 79 NA Homo sapiens

GOA IEI008361 Protein protein interactors of human gene MTREX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTREX (SwissProt ID= (more detail) 66 17535438 Homo sapiens

I2D WAG000195 Cell cycle Mitotic cell cycle progression is accomplished through a reproducible sequence of events, D replicat (more detail) 100 NA Homo sapiens

KEGG WIG001930 Adipogenesis Adipogenesis (more detail) 132 NA Homo sapiens

WikiPathway TAX027247 GO:0051897 biological process positive regulation of protein kinase B signaling Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, (more detail) 156 NA Homo sapiens

GOA TAX028323 GO:0061138 biological process morphogenesis of a branching epithelium The process in which the anatomical structures of a branched epithelium are generated and organized. (more detail) 140 NA Homo sapiens

GOA WIG001929 TNF alpha Signaling Pathway TNF alpha Signaling Pathway (more detail) 86 NA Homo sapiens

WikiPathway IEI005678 Protein protein interactors of human gene H3 3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H3-3A (SwissProt ID= (more detail) 115 17535438 Homo sapiens

I2D IEI013353 Protein protein interactors of human gene TAF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF6 (SwissProt ID=P (more detail) 57 17535438 Homo sapiens

I2D IEI011200 Protein protein interactors of human gene RFC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RFC1 (SwissProt ID=P (more detail) 60 17535438 Homo sapiens

I2D MAX001344 DNA repair and replication genes up regulated in melanoma patients who will relapse vs patients who will not. We have identified a gene-profile signature for human primary malignant melanoma associated with met (more detail) 60 NA Homo sapiens

MSigDB IEI002851 Protein protein interactors of human gene COPS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COPS3 (SwissProt ID= (more detail) 71 17535438 Homo sapiens

I2D TAX030000 GO:0072395 biological process signal transduction involved in cell cycle checkpoint A signal transduction process that contributes to a cell cycle checkpoint. (more detail) 71 NA Homo sapiens

GOA IEI011529 Protein protein interactors of human gene RPL32 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL32 (SwissProt ID= (more detail) 71 17535438 Homo sapiens

I2D TAX016672 GO:0006910 biological process phagocytosis, recognition The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particul (more detail) 71 NA Homo sapiens

GOA WIG001290 Genes involved in Transcriptional Regulation of White Adipocyte Differentiation (more detail) 71 NA Homo sapiens

MSigDB WIG001486 ErbB2 ErbB3 Heterodimers ErbB2-ErbB3 Heterodimers (more detail) 71 NA Homo sapiens

Protein Lounge IEI003038 Protein protein interactors of human gene CSE1L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSE1L (SwissProt ID= (more detail) 117 17535438 Homo sapiens

I2D TAX013214 GO:0000018 biological process regulation of DNA recombination Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic proce (more detail) 81 NA Homo sapiens

GOA TAX013547 GO:0000932 cellular component P body A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Pr (more detail) 81 NA Homo sapiens

GOA IEI010633 Protein protein interactors of human gene PSMB4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMB4 (SwissProt ID= (more detail) 76 17535438 Homo sapiens

I2D IEI014597 Protein protein interactors of human gene UBE2W from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2W (SwissProt ID= (more detail) 76 17535438 Homo sapiens

I2D WIG001199 Genes involved in Signaling by ERBB4 (more detail) 88 NA Homo sapiens

MSigDB WEX000005 Apoptosis The genes related to apoptosis (cell function) in tumor using next-generation sequencer (NGS) readou (more detail) 121 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas WIG001182 Genes involved in SCF beta TrCP mediated degradation of Emi1 (more detail) 50 NA Homo sapiens

MSigDB IEI011576 Protein protein interactors of human gene RPS15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS15 (SwissProt ID= (more detail) 97 17535438 Homo sapiens

I2D IEI015025 Protein protein interactors of human gene WDR77 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR77 (SwissProt ID= (more detail) 97 17535438 Homo sapiens

I2D MEX002045 Genes associated with Kinase Inhibitor Cediranib Genes associated with Kinase Inhibitor Cediranib, curated by the Drug Signature Database (DSigDB). (more detail) 46 25990557 Homo sapiens

DSigDB TAX001369 Genes annotated by the GO term GO:0017171. Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). (more detail) 46 NA Homo sapiens

MSigDB TAX022138 GO:0033558 molecular function protein deacetylase activity Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate. (more detail) 46 NA Homo sapiens

GOA TAX015029 GO:0004177 molecular function aminopeptidase activity Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain. (more detail) 46 NA Homo sapiens

GOA TAX029167 GO:0070888 molecular function E box binding Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CA (more detail) 46 NA Homo sapiens

GOA TAX017941 GO:0010501 biological process RNA secondary structure unwinding The process in which a secondary structure of RNA are broken or 'melted'. (more detail) 46 NA Homo sapiens

GOA FEX019206 The diagnosis of Adenocarcinoma, NOS (stage iib) in Head of pancreas (TCGA F2 6880 FPKM>=100) Transcript expression levels summarized per gene in 7932 samples from 17 different cancer types. The (more detail) 129 25613900 Homo sapiens

HPA-TCGA IEI013237 Protein protein interactors of human gene SUV39H1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUV39H1 (SwissProt I (more detail) 153 17535438 Homo sapiens

I2D MOX000463 Genes associated with Computational Drug Signature wortmannin Genes associated with Computational Drug Signature wortmannin, curated by the Drug Signature Databas (more detail) 145 25990557 Homo sapiens

DSigDB MEX003327 Genes associated with Perturbagen Signature HC toxin Genes associated with Perturbagen Signature HC toxin, curated by the Drug Signature Database (DSigDB (more detail) 145 25990557 Homo sapiens

DSigDB TAX020740 GO:0030968 biological process endoplasmic reticulum unfolded protein response The series of molecular signals generated as a consequence of the presence of unfolded proteins in t (more detail) 101 NA Homo sapiens

GOA FOX000026 Neighborhood of CSNK2B Neighborhood of CSNK2B casein kinase 2, beta polypeptide in the GCM expression compendium (more detail) 92 NA Homo sapiens

MSigDB WEX000085 Prostate Cancer The genes related to prostate cancer (physiology & disease) in tumor using next-generation sequencer (more detail) 92 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI007699 Protein protein interactors of human gene MAPK9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPK9 (SwissProt ID= (more detail) 114 17535438 Homo sapiens

I2D FOX000092 Neighborhood of APEX1 Neighborhood of APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 in the GNF2 expression co (more detail) 85 NA Homo sapiens

MSigDB IEI002290 Protein protein interactors of human gene CDT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDT1 (SwissProt ID=Q (more detail) 53 17535438 Homo sapiens

I2D WIG001055 Genes involved in p53 Dependent G1 DNA Damage Response (more detail) 53 NA Homo sapiens

MSigDB TAX030903 GO:0097525 cellular component spliceosomal snRNP complex A ribonucleoprotein complex involved in formation of the spliceosome and composed of one or more snR (more detail) 62 NA Homo sapiens

GOA TAX030002 GO:0072401 biological process signal transduction involved in DNA integrity checkpoint A signal transduction process that contributes to a DNA integrity checkpoint. (more detail) 70 NA Homo sapiens

GOA TAX030006 GO:0072422 biological process signal transduction involved in DNA damage checkpoint A signal transduction process that contributes to a DNA damage checkpoint. (more detail) 70 NA Homo sapiens

GOA IEI000980 Protein protein interactors of human gene ASH2L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASH2L (SwissProt ID= (more detail) 75 17535438 Homo sapiens

I2D IEI012997 Protein protein interactors of human gene SRSF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF2 (SwissProt ID= (more detail) 105 17535438 Homo sapiens

I2D TAX017804 GO:0009913 biological process epidermal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epidermal c (more detail) 87 NA Homo sapiens

GOA IEI004259 Protein protein interactors of human gene ERG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERG (SwissProt ID=P1 (more detail) 87 17535438 Homo sapiens

I2D IEI012696 Protein protein interactors of human gene SNRPD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRPD2 (SwissProt ID (more detail) 122 17535438 Homo sapiens

I2D TAX018909 GO:0016202 biological process regulation of striated muscle tissue development Any process that modulates the frequency, rate or extent of striated muscle development. (more detail) 124 NA Homo sapiens

GOA TAX021584 GO:0032479 biological process regulation of type I interferon production Any process that modulates the frequency, rate, or extent of interferon type I production. Type I in (more detail) 107 NA Homo sapiens

GOA MOX016260 Genes associated with Computational Drug Signature trichostatin A Genes associated with Computational Drug Signature trichostatin A, curated by the Drug Signature Dat (more detail) 128 25990557 Homo sapiens

DSigDB IEI002057 Protein protein interactors of human gene CCNT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNT1 (SwissProt ID= (more detail) 67 17535438 Homo sapiens

I2D IEI007843 Protein protein interactors of human gene MED14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED14 (SwissProt ID= (more detail) 67 17535438 Homo sapiens

I2D IEI005580 Protein protein interactors of human gene GTF2F1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2F1 (SwissProt ID (more detail) 67 17535438 Homo sapiens

I2D IEI008307 Protein protein interactors of human gene MTA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTA1 (SwissProt ID=Q (more detail) 82 17535438 Homo sapiens

I2D TAX001433 Genes annotated by the GO term GO:0046914. Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. (more detail) 109 NA Homo sapiens

MSigDB WIG001039 Genes involved in Nucleotide Excision Repair (more detail) 49 NA Homo sapiens

MSigDB WIG001056 Genes involved in p53 Independent G1/S DNA damage checkpoint (more detail) 49 NA Homo sapiens

MSigDB WIG000969 Genes involved in MAP kinase activation in TLR cascade (more detail) 49 NA Homo sapiens

MSigDB MEX001876 Genes associated with Kinase Inhibitor AZD 9291 Genes associated with Kinase Inhibitor AZD-9291, curated by the Drug Signature Database (DSigDB). (more detail) 49 25990557 Homo sapiens

DSigDB IEI007862 Protein protein interactors of human gene MED6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED6 (SwissProt ID=O (more detail) 49 17535438 Homo sapiens

I2D WIG001649 Ras Pathway Ras Pathway (more detail) 146 NA Homo sapiens

Protein Lounge WEX000024 EMT The genes related to emt (cell function) in tumor, stroma using next-generation sequencer (NGS) read (more detail) 98 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas MOX015584 Genes associated with Computational Drug Signature Toxoflavin Genes associated with Computational Drug Signature Toxoflavin, curated by the Drug Signature Databas (more detail) 98 25990557 Homo sapiens

DSigDB TAX020525 GO:0030490 biological process maturation of SSU rRNA Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molec (more detail) 45 NA Homo sapiens

GOA TAX017083 GO:0008138 molecular function protein tyrosine/serine/threonine phosphatase activity Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine pho (more detail) 45 NA Homo sapiens

GOA MEX002029 Genes associated with Kinase Inhibitor SU11652 Genes associated with Kinase Inhibitor SU11652, curated by the Drug Signature Database (DSigDB). (more detail) 45 25990557 Homo sapiens

DSigDB TAX016247 GO:0006306 biological process DNA methylation The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. (more detail) 45 NA Homo sapiens

GOA TAX016246 GO:0006305 biological process DNA alkylation The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also (more detail) 45 NA Homo sapiens

GOA TAX001372 Genes annotated by the GO term GO:0008236. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). (more detail) 45 NA Homo sapiens

MSigDB IEI010631 Protein protein interactors of human gene PSMB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMB2 (SwissProt ID= (more detail) 77 17535438 Homo sapiens

I2D IEI005852 Protein protein interactors of human gene HIPK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HIPK2 (SwissProt ID= (more detail) 64 17535438 Homo sapiens

I2D TAX020805 GO:0031090 cellular component organelle membrane A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane (more detail) 2659 NA Homo sapiens

GOA TAX026873 GO:0051213 molecular function dioxygenase activity Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule (more detail) 91 NA Homo sapiens

GOA MOX003786 Genes associated with Computational Drug Signature camptothecin Genes associated with Computational Drug Signature camptothecin, curated by the Drug Signature Datab (more detail) 115 25990557 Homo sapiens

DSigDB WIG001278 Genes involved in Toll Receptor Cascades (more detail) 115 NA Homo sapiens

MSigDB IEI007857 Protein protein interactors of human gene MED28 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED28 (SwissProt ID= (more detail) 84 17535438 Homo sapiens

I2D WIG001639 Protein Acetylation and Deacetylation Protein Acetylation and Deacetylation (more detail) 52 NA Homo sapiens

Protein Lounge IEI009018 Protein protein interactors of human gene NR0B2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR0B2 (SwissProt ID= (more detail) 61 17535438 Homo sapiens

I2D IEI001016 Protein protein interactors of human gene ATF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATF3 (SwissProt ID=P (more detail) 61 17535438 Homo sapiens

I2D TAX013261 GO:0000118 cellular component histone deacetylase complex A protein complex that possesses histone deacetylase activity. (more detail) 61 NA Homo sapiens

GOA WAG000663 Regulation of Telomerase (more detail) 61 NA Homo sapiens

NCI-Nature Curated WEX000054 Leukemia The genes related to leukemia (physiology & disease) in tumor using next-generation sequencer (NGS) (more detail) 93 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI007757 Protein protein interactors of human gene MBD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MBD3 (SwissProt ID=O (more detail) 79 17535438 Homo sapiens

I2D IEI010405 Protein protein interactors of human gene PPP5C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP5C (SwissProt ID= (more detail) 121 17535438 Homo sapiens

I2D WAG001048 Regulation of nuclear SMAD2/3 signaling (more detail) 69 NA Homo sapiens

NCI-Nature Curated TAX025285 GO:0045814 biological process negative regulation of gene expression, epigenetic Any epigenetic process that stops, prevents or reduces the rate of gene expression. (more detail) 58 NA Homo sapiens

GOA WIG000740 Genes involved in CDT1 association with the CDC6:ORC:origin complex (more detail) 55 NA Homo sapiens

MSigDB IEI004025 Protein protein interactors of human gene EIF2AK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF2AK2 (SwissProt I (more detail) 106 17535438 Homo sapiens

I2D TAX016471 GO:0006612 biological process protein targeting to membrane The process of directing proteins towards a membrane, usually using signals contained within the pro (more detail) 129 NA Homo sapiens

GOA IEI013223 Protein protein interactors of human gene SUPT5H from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUPT5H (SwissProt ID (more detail) 95 17535438 Homo sapiens

I2D IEI000180 Protein protein interactors of human gene ACTL6A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACTL6A (SwissProt ID (more detail) 88 17535438 Homo sapiens

I2D IEI008936 Protein protein interactors of human gene NOLC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOLC1 (SwissProt ID= (more detail) 76 17535438 Homo sapiens

I2D TAX021020 GO:0031490 molecular function chromatin DNA binding Interacting selectively and non-covalently with DNA that is assembled into chromatin. (more detail) 76 NA Homo sapiens

GOA TAX001245 Genes annotated by the GO term GO:0008237. (more detail) 48 NA Homo sapiens

MSigDB WIG001314 Genes involved in Vif mediated degradation of APOBEC3G (more detail) 48 NA Homo sapiens

MSigDB IEI001422 Protein protein interactors of human gene BRCA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRCA2 (SwissProt ID= (more detail) 71 17535438 Homo sapiens

I2D TAX019213 GO:0016782 molecular function transferase activity, transferring sulfur containing groups Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (accepto (more detail) 71 NA Homo sapiens

GOA WIG001024 Genes involved in NFkB and MAP kinases activation mediated by TLR4 signaling repertoire (more detail) 71 NA Homo sapiens

MSigDB IEI007665 Protein protein interactors of human gene MAP3K5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP3K5 (SwissProt ID (more detail) 99 17535438 Homo sapiens

I2D TAX019289 GO:0016893 molecular function endonuclease activity, active with either ribo or deoxyribonucleic acids and producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yi (more detail) 44 NA Homo sapiens

GOA IEI007854 Protein protein interactors of human gene MED25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED25 (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D TAX029253 GO:0071011 cellular component precatalytic spliceosome A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP t (more detail) 44 NA Homo sapiens

GOA TAX023813 GO:0042398 biological process cellular modified amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of compounds derived from amino acids (more detail) 44 NA Homo sapiens

GOA TAX015030 GO:0004180 molecular function carboxypeptidase activity Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a p (more detail) 44 NA Homo sapiens

GOA TAX016196 GO:0006221 biological process pyrimidine nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compoun (more detail) 44 NA Homo sapiens

GOA WAG000326 SCF beta TrCP mediated degradation of Emi1 (more detail) 44 NA Homo sapiens

Reactome WAG001321 Elongation of Intron Containing Transcripts and co transcriptional mRNA splicing (more detail) 44 NA Homo sapiens

Reactome MEX002205 Genes associated with Kinase Inhibitor PKR Inhibitor Genes associated with Kinase Inhibitor PKR Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 44 25990557 Homo sapiens

DSigDB WIG000573 Nucleotide excision repair Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by c (more detail) 44 NA Homo sapiens

MSigDB TAX015117 GO:0004407 molecular function histone deacetylase activity Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This react (more detail) 44 NA Homo sapiens

GOA TAX016181 GO:0006195 biological process purine nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound co (more detail) 44 NA Homo sapiens

GOA IEI010634 Protein protein interactors of human gene PSMB5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMB5 (SwissProt ID= (more detail) 101 17535438 Homo sapiens

I2D IEI013110 Protein protein interactors of human gene STIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STIP1 (SwissProt ID= (more detail) 118 17535438 Homo sapiens

I2D IEI014393 Protein protein interactors of human gene TSR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TSR1 (SwissProt ID=Q (more detail) 92 17535438 Homo sapiens

I2D IEI002034 Protein protein interactors of human gene CCNB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNB1 (SwissProt ID= (more detail) 103 17535438 Homo sapiens

I2D IEI005938 Protein protein interactors of human gene HNRNPDL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPDL (SwissProt I (more detail) 124 17535438 Homo sapiens

I2D TAX032893 GO:1903321 biological process negative regulation of protein modification by small protein conjugation or removal Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by (more detail) 78 NA Homo sapiens

GOA TAX017227 GO:0008375 molecular function acetylglucosaminyltransferase activity Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a suga (more detail) 51 NA Homo sapiens

GOA TAX020328 GO:0030145 molecular function manganese ion binding Interacting selectively and non-covalently with manganese (Mn) ions. (more detail) 51 NA Homo sapiens

GOA WIG000793 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) (more detail) 51 NA Homo sapiens

MSigDB WIG000757 Genes involved in Circadian Clock (more detail) 51 NA Homo sapiens

MSigDB WIG001607 P2Y Receptor Signaling P2Y Receptor Signaling (more detail) 126 NA Homo sapiens

Protein Lounge WIG001212 Genes involved in Signaling by NOTCH1 (more detail) 68 NA Homo sapiens

MSigDB TAX032553 GO:1902554 cellular component serine/threonine protein kinase complex A protein complex which is capable of protein serine/threonine kinase activity. (more detail) 85 NA Homo sapiens

GOA IEI010491 Protein protein interactors of human gene PRKCZ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRKCZ (SwissProt ID= (more detail) 144 17535438 Homo sapiens

I2D IEI003307 Protein protein interactors of human gene DAXX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DAXX (SwissProt ID=Q (more detail) 144 17535438 Homo sapiens

I2D IEI006766 Protein protein interactors of human gene KDM5B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM5B (SwissProt ID= (more detail) 73 17535438 Homo sapiens

I2D IEI006278 Protein protein interactors of human gene IK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IK (SwissProt ID=Q13 (more detail) 73 17535438 Homo sapiens

I2D IEI003948 Protein protein interactors of human gene EEF1A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EEF1A2 (SwissProt ID (more detail) 132 17535438 Homo sapiens

I2D IEI014599 Protein protein interactors of human gene UBE3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE3A (SwissProt ID= (more detail) 132 17535438 Homo sapiens

I2D MAX003097 Down regulated by induction of exogenous BRCA1 in EcR 293 cells Loss of function of BRCA1 caused by inherited mutation and tissue-specific somatic mutation leads to (more detail) 134 NA Homo sapiens

MSigDB IEI007005 Protein protein interactors of human gene KRT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KRT1 (SwissProt ID=P (more detail) 136 17535438 Homo sapiens

I2D MOX004830 Genes associated with Computational Drug Signature ursodiol Genes associated with Computational Drug Signature ursodiol, curated by the Drug Signature Database (more detail) 136 25990557 Homo sapiens

DSigDB TAX019200 GO:0016763 molecular function transferase activity, transferring pentosyl groups Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). (more detail) 57 NA Homo sapiens

GOA TAX020782 GO:0031060 biological process regulation of histone methylation Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups t (more detail) 57 NA Homo sapiens

GOA WIG001181 Genes involved in SCF(Skp2) mediated degradation of p27/p21 (more detail) 54 NA Homo sapiens

MSigDB MEX001851 Genes associated with Kinase Inhibitor GW305074X Genes associated with Kinase Inhibitor GW305074X, curated by the Drug Signature Database (DSigDB). (more detail) 54 25990557 Homo sapiens

DSigDB TAX000129 Genes annotated by the GO term GO:0016568. The alteration of DNA or protein in chromatin, which may result in changing the chromatin structure. (more detail) 54 NA Homo sapiens

MSigDB IEI012085 Protein protein interactors of human gene SF3B4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SF3B4 (SwissProt ID= (more detail) 109 17535438 Homo sapiens

I2D IEI012236 Protein protein interactors of human gene SIRT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIRT2 (SwissProt ID= (more detail) 109 17535438 Homo sapiens

I2D TAX023996 GO:0042752 biological process regulation of circadian rhythm Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm i (more detail) 96 NA Homo sapiens

GOA IEI014572 Protein protein interactors of human gene UBE2E2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2E2 (SwissProt ID (more detail) 80 17535438 Homo sapiens

I2D IEI000404 Protein protein interactors of human gene AIM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AIM2 (SwissProt ID=O (more detail) 111 17535438 Homo sapiens

I2D WIG001558 IL 2 Pathway IL-2 Pathway (more detail) 65 NA Homo sapiens

Protein Lounge FOX000084 Neighborhood of TPT1 Neighborhood of TPT1 tumor protein, translationally-controlled 1 in the GCM expression compendium (more detail) 65 NA Homo sapiens

MSigDB IEI010650 Protein protein interactors of human gene PSMD13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD13 (SwissProt ID (more detail) 89 17535438 Homo sapiens

I2D WIG000717 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 (more detail) 47 NA Homo sapiens

MSigDB TAX001274 Genes annotated by the GO term GO:0016779. Catalysis of the transfer of a nucleotidyl group to a reactant. (more detail) 47 NA Homo sapiens

MSigDB WIG000739 Genes involved in CDK mediated phosphorylation and removal of Cdc6 (more detail) 47 NA Homo sapiens

MSigDB TAX000335 Genes annotated by the GO term GO:0006643. The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane. (more detail) 100 NA Homo sapiens

MSigDB IEI007850 Protein protein interactors of human gene MED21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED21 (SwissProt ID= (more detail) 62 17535438 Homo sapiens

I2D TAX024839 GO:0044773 biological process mitotic DNA damage checkpoint A mitotic cell cycle checkpoint that detects and negatively regulates progression through the cell c (more detail) 43 NA Homo sapiens

GOA TAX017506 GO:0009101 biological process glycoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that co (more detail) 43 NA Homo sapiens

GOA TAX017581 GO:0009187 biological process cyclic nucleotide metabolic process The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phospha (more detail) 43 NA Homo sapiens

GOA TAX024546 GO:0043966 biological process histone H3 acetylation The modification of histone H3 by the addition of an acetyl group. (more detail) 43 NA Homo sapiens

GOA TAX017746 GO:0009712 biological process catechol containing compound metabolic process The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) (more detail) 43 NA Homo sapiens

GOA WAG000730 Regulation of ornithine decarboxylase (ODC) (more detail) 43 NA Homo sapiens

Reactome TAX014103 GO:0002181 biological process cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This i (more detail) 43 NA Homo sapiens

GOA MEX001367 Genes associated with Kinase Inhibitor Linifanib Genes associated with Kinase Inhibitor Linifanib, curated by the Drug Signature Database (DSigDB). (more detail) 43 25990557 Homo sapiens

DSigDB TAX016450 GO:0006584 biological process catecholamine metabolic process The chemical reactions and pathways involving any of a group of physiologically important biogenic a (more detail) 43 NA Homo sapiens

GOA WAG001081 CDK mediated phosphorylation and removal of Cdc6 (more detail) 43 NA Homo sapiens

Reactome WAG000936 Vif mediated degradation of APOBEC3G (more detail) 43 NA Homo sapiens

Reactome WAG000925 Ubiquitin dependent degradation of Cyclin D1 (more detail) 43 NA Homo sapiens

Reactome IEI004979 Protein protein interactors of human gene FZR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FZR1 (SwissProt ID=Q (more detail) 102 17535438 Homo sapiens

I2D IEI007799 Protein protein interactors of human gene MCM6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCM6 (SwissProt ID=Q (more detail) 102 17535438 Homo sapiens

I2D IEI001873 Protein protein interactors of human gene CBX3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CBX3 (SwissProt ID=Q (more detail) 125 17535438 Homo sapiens

I2D IEI004585 Protein protein interactors of human gene FASN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FASN (SwissProt ID=P (more detail) 127 17535438 Homo sapiens

I2D TAX033189 GO:1903900 biological process regulation of viral life cycle Any process that modulates the frequency, rate or extent of viral life cycle. (more detail) 131 NA Homo sapiens

GOA FOX000286 Neighborhood of EIF4A2 Neighborhood of EIF4A2 eukaryotic translation initiation factor 4A, isoform 2 in the MORF expressio (more detail) 131 NA Homo sapiens

MSigDB TAX013744 GO:0001650 cellular component fibrillar center A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by t (more detail) 131 NA Homo sapiens

GOA IEI014752 Protein protein interactors of human gene USP11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP11 (SwissProt ID= (more detail) 133 17535438 Homo sapiens

I2D WEX000101 TLR Signaling The genes related to tlr signaling (innate immunity) in tumor using next-generation sequencer (NGS) (more detail) 133 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas TAX021383 GO:0032204 biological process regulation of telomere maintenance Any process that modulates the frequency, rate or extent of a process that affects and monitors the (more detail) 77 NA Homo sapiens

GOA IEI011533 Protein protein interactors of human gene RPL36 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL36 (SwissProt ID= (more detail) 104 17535438 Homo sapiens

I2D IEI012960 Protein protein interactors of human gene SREBF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SREBF1 (SwissProt ID (more detail) 59 17535438 Homo sapiens

I2D IEI007210 Protein protein interactors of human gene LEF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LEF1 (SwissProt ID=Q (more detail) 59 17535438 Homo sapiens

I2D WIG001802 BRCA1 Pathway BRCA1 Pathway (more detail) 59 NA Homo sapiens

Protein Lounge IEI012962 Protein protein interactors of human gene SREK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SREK1 (SwissProt ID= (more detail) 67 17535438 Homo sapiens

I2D WIG001981 G1 to S cell cycle control G1 to S cell cycle control (more detail) 67 NA Homo sapiens

WikiPathway TAX016123 GO:0006090 biological process pyruvate metabolic process The chemical reactions and pathways involving pyruvate, 2-oxopropanoate. (more detail) 67 NA Homo sapiens

GOA IEI013218 Protein protein interactors of human gene SUPT16H from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUPT16H (SwissProt I (more detail) 106 17535438 Homo sapiens

I2D IEI000561 Protein protein interactors of human gene ANAPC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC5 (SwissProt ID (more detail) 50 17535438 Homo sapiens

I2D TAX031009 GO:0098531 molecular function transcription factor activity, direct ligand regulated sequence specific DNA binding A DNA-binding transcription factor activity that is directly regulated by binding of a ligand to the (more detail) 50 NA Homo sapiens

GOA WAG000056 CDT1 association with the CDC6:ORC:origin complex (more detail) 50 NA Homo sapiens

Reactome TAX015458 GO:0004879 molecular function nuclear receptor activity Combining with a signal and transmitting the signal to the transcriptional machinery by interacting (more detail) 50 NA Homo sapiens

GOA TAX000174 Genes annotated by the GO term GO:0006261. The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA dependent DNA polymerases that synthesize the new strands. (more detail) 56 NA Homo sapiens

MSigDB IEI003108 Protein protein interactors of human gene CTDP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTDP1 (SwissProt ID= (more detail) 53 17535438 Homo sapiens

I2D TAX025248 GO:0045739 biological process positive regulation of DNA repair Any process that activates or increases the frequency, rate or extent of DNA repair. (more detail) 53 NA Homo sapiens

GOA IEI013471 Protein protein interactors of human gene TCEA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCEA1 (SwissProt ID= (more detail) 53 17535438 Homo sapiens

I2D WIG000512 ErbB signaling pathway The ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor l (more detail) 86 NA Homo sapiens

MSigDB MOX001726 Genes associated with Computational Drug Signature IN1152 Genes associated with Computational Drug Signature IN1152, curated by the Drug Signature Database (D (more detail) 86 25990557 Homo sapiens

DSigDB TAX033899 GO:1905369 cellular component endopeptidase complex A protein complex which is capable of endopeptidase activity. (more detail) 64 NA Homo sapiens

GOA TAX016580 GO:0006766 biological process vitamin metabolic process The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of un (more detail) 116 NA Homo sapiens

GOA WEX000074 Notch Signaling The genes related to notch signaling (signaling pathways) in tumor using next-generation sequencer ( (more detail) 74 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas MOX005153 Genes associated with Computational Drug Signature luteolin Genes associated with Computational Drug Signature luteolin, curated by the Drug Signature Database (more detail) 118 25990557 Homo sapiens

DSigDB TAX024173 GO:0043130 molecular function ubiquitin binding Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to o (more detail) 69 NA Homo sapiens

GOA IEI003412 Protein protein interactors of human gene DDX20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX20 (SwissProt ID= (more detail) 69 17535438 Homo sapiens

I2D TAX032320 GO:1901983 biological process regulation of protein acetylation Any process that modulates the frequency, rate or extent of protein acetylation. (more detail) 69 NA Homo sapiens

GOA FOX000159 Neighborhood of KPNB1 Neighborhood of KPNB1 karyopherin (importin) beta 1 in the GNF2 expression compendium (more detail) 69 NA Homo sapiens

MSigDB IEI009370 Protein protein interactors of human gene OTUB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OTUB1 (SwissProt ID= (more detail) 81 17535438 Homo sapiens

I2D IEI014474 Protein protein interactors of human gene TUBB4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TUBB4A (SwissProt ID (more detail) 122 17535438 Homo sapiens

I2D WIG001586 NF KappaB Family Pathway NF-KappaB Family Pathway (more detail) 122 NA Homo sapiens

Protein Lounge TAX024388 GO:0043487 biological process regulation of RNA stability Any process that modulates the propensity of RNA molecules to degradation. Includes processes that b (more detail) 126 NA Homo sapiens

GOA IEI007798 Protein protein interactors of human gene MCM5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCM5 (SwissProt ID=P (more detail) 101 17535438 Homo sapiens

I2D IEI014155 Protein protein interactors of human gene TRA2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRA2B (SwissProt ID= (more detail) 101 17535438 Homo sapiens

I2D IEI006783 Protein protein interactors of human gene KHSRP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KHSRP (SwissProt ID= (more detail) 132 17535438 Homo sapiens

I2D WAG001504 Degradation of beta catenin by the destruction complex (more detail) 46 NA Homo sapiens

Reactome IEI011079 Protein protein interactors of human gene RBM25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM25 (SwissProt ID= (more detail) 61 17535438 Homo sapiens

I2D IEI013319 Protein protein interactors of human gene TAB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAB2 (SwissProt ID=Q (more detail) 103 17535438 Homo sapiens

I2D TAX022581 GO:0034644 biological process cellular response to UV Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 76 NA Homo sapiens

GOA WIG001921 Prolactin Signaling Pathway Prolactin Signaling Pathway (more detail) 76 NA Homo sapiens

WikiPathway TAX022853 GO:0035384 biological process thioester biosynthetic process The chemical reactions and pathways resulting in the formation of a thioester, a compound of general (more detail) 42 NA Homo sapiens

GOA TAX029570 GO:0071616 biological process acyl CoA biosynthetic process The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzy (more detail) 42 NA Homo sapiens

GOA TAX024050 GO:0042866 biological process pyruvate biosynthetic process The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate. (more detail) 42 NA Homo sapiens

GOA TAX022291 GO:0034061 molecular function DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synth (more detail) 42 NA Homo sapiens

GOA TAX015337 GO:0004712 molecular function protein serine/threonine/tyrosine kinase activity Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein (more detail) 42 NA Homo sapiens

GOA WIG000764 Genes involved in Cleavage of Growing Transcript in the Termination Region (more detail) 42 NA Homo sapiens

MSigDB WAG001550 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (more detail) 42 NA Homo sapiens

Reactome MEX002372 Genes associated with Kinase Inhibitor Sorafenib Genes associated with Kinase Inhibitor Sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 42 25990557 Homo sapiens

DSigDB WAG001344 Regulation of activated PAK 2p34 by proteasome mediated degradation (more detail) 42 NA Homo sapiens

Reactome MEX001977 Genes associated with Kinase Inhibitor MLN8054 Genes associated with Kinase Inhibitor MLN8054, curated by the Drug Signature Database (DSigDB). (more detail) 42 25990557 Homo sapiens

DSigDB TAX026204 GO:0048524 biological process positive regulation of viral process Any process that activates or increases the frequency, rate or extent of a multi-organism process in (more detail) 83 NA Homo sapiens

GOA IEI004798 Protein protein interactors of human gene FKBP8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FKBP8 (SwissProt ID= (more detail) 92 17535438 Homo sapiens

I2D IEI009889 Protein protein interactors of human gene PIAS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIAS2 (SwissProt ID= (more detail) 92 17535438 Homo sapiens

I2D IEI012693 Protein protein interactors of human gene SNRPB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRPB2 (SwissProt ID (more detail) 66 17535438 Homo sapiens

I2D TAX029028 GO:0070603 cellular component SWI/SNF superfamily type complex A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the cata (more detail) 71 NA Homo sapiens

GOA WIG000637 T cell receptor signaling pathway Activation of T lymphocytes is a key event for an efficient response of the immune system. It requir (more detail) 107 NA Homo sapiens

MSigDB IEI010813 Protein protein interactors of human gene PYHIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PYHIN1 (SwissProt ID (more detail) 107 17535438 Homo sapiens

I2D TAX022560 GO:0034614 biological process cellular response to reactive oxygen species Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 107 NA Homo sapiens

GOA IEI010635 Protein protein interactors of human gene PSMB6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMB6 (SwissProt ID= (more detail) 58 17535438 Homo sapiens

I2D IEI004566 Protein protein interactors of human gene FANCC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FANCC (SwissProt ID= (more detail) 58 17535438 Homo sapiens

I2D MEX002401 Genes associated with Kinase Inhibitor Pazopanib Genes associated with Kinase Inhibitor Pazopanib, curated by the Drug Signature Database (DSigDB). (more detail) 49 25990557 Homo sapiens

DSigDB MEX001534 Genes associated with Kinase Inhibitor Pazopanib Genes associated with Kinase Inhibitor Pazopanib, curated by the Drug Signature Database (DSigDB). (more detail) 49 25990557 Homo sapiens

DSigDB IEI011748 Protein protein interactors of human gene S100A9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene S100A9 (SwissProt ID (more detail) 111 17535438 Homo sapiens

I2D WIG000091 IL2 mediated signaling events (more detail) 55 NA Homo sapiens

MSigDB WIG001533 Growth Hormone Signaling Growth Hormone Signaling (more detail) 55 NA Homo sapiens

Protein Lounge IEI006434 Protein protein interactors of human gene INTS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS3 (SwissProt ID= (more detail) 55 17535438 Homo sapiens

I2D TAX020687 GO:0030880 cellular component RNA polymerase complex Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one (more detail) 55 NA Homo sapiens

GOA IEI011641 Protein protein interactors of human gene RRP1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRP1B (SwissProt ID= (more detail) 55 17535438 Homo sapiens

I2D FEX001267 Leukemia Durig03 88genes Table 4. Ribosomal cluster identified by hierarchical cluster analysis (more detail) 78 12456497 Homo sapiens

GeneSigDB IEI011441 Protein protein interactors of human gene RNF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF4 (SwissProt ID=P (more detail) 52 17535438 Homo sapiens

I2D WIG000016 Regulation of Androgen receptor activity (more detail) 52 NA Homo sapiens

MSigDB IEI011556 Protein protein interactors of human gene RPN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPN1 (SwissProt ID=P (more detail) 96 17535438 Homo sapiens

I2D IEI010692 Protein protein interactors of human gene PTEN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTEN (SwissProt ID=P (more detail) 115 17535438 Homo sapiens

I2D IEI014581 Protein protein interactors of human gene UBE2K from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2K (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D TAX013446 GO:0000502 cellular component proteasome complex A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and s (more detail) 63 NA Homo sapiens

GOA WIG001222 Genes involved in Signaling by Wnt (more detail) 63 NA Homo sapiens

MSigDB IEI001295 Protein protein interactors of human gene BCLAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCLAF1 (SwissProt ID (more detail) 63 17535438 Homo sapiens

I2D MOX016619 Genes associated with Computational Drug Signature cycloheximide Genes associated with Computational Drug Signature cycloheximide, curated by the Drug Signature Data (more detail) 121 25990557 Homo sapiens

DSigDB TAX018796 GO:0015935 cellular component small ribosomal subunit The smaller of the two subunits of a ribosome. (more detail) 73 NA Homo sapiens

GOA TAX000240 Genes annotated by the GO term GO:0009101. The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues other than as a moiety of nucleic acid; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. (more detail) 73 NA Homo sapiens

MSigDB WIG000566 Neurotrophin signaling pathway Neurotrophins are a family of trophic factors involved in differentiation and survival of neural cel (more detail) 125 NA Homo sapiens

MSigDB IEI014805 Protein protein interactors of human gene USP9X from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP9X (SwissProt ID= (more detail) 127 17535438 Homo sapiens

I2D IEI000659 Protein protein interactors of human gene ANXA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANXA2 (SwissProt ID= (more detail) 127 17535438 Homo sapiens

I2D TAX026227 GO:0048568 biological process embryonic organ development Development, taking place during the embryonic phase, of a tissue or tissues that work together to p (more detail) 127 NA Homo sapiens

GOA IEI010814 Protein protein interactors of human gene PYM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PYM1 (SwissProt ID=Q (more detail) 60 17535438 Homo sapiens

I2D WIG001031 Genes involved in NOTCH1 Intracellular Domain Regulates Transcription (more detail) 45 NA Homo sapiens

MSigDB WAG001555 SCF(Skp2) mediated degradation of p27/p21 (more detail) 45 NA Homo sapiens

Reactome WIG001677 SMAD Signaling Network SMAD Signaling Network (more detail) 91 NA Homo sapiens

Protein Lounge WAG001226 ErbB signaling pathway The ErbB family of receptor tyrosine kises (RTKs) couples binding of extracellular growth factor lig (more detail) 75 NA Homo sapiens

KEGG IEI013336 Protein protein interactors of human gene TAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF1 (SwissProt ID=P (more detail) 82 17535438 Homo sapiens

I2D IEI012964 Protein protein interactors of human gene SRF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRF (SwissProt ID=P1 (more detail) 82 17535438 Homo sapiens

I2D IEI001061 Protein protein interactors of human gene ATP1A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP1A1 (SwissProt ID (more detail) 106 17535438 Homo sapiens

I2D IEI007751 Protein protein interactors of human gene MAX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAX (SwissProt ID=P6 (more detail) 108 17535438 Homo sapiens

I2D IEI012995 Protein protein interactors of human gene SRSF11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF11 (SwissProt ID (more detail) 70 17535438 Homo sapiens

I2D IEI012757 Protein protein interactors of human gene SON from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SON (SwissProt ID=P1 (more detail) 70 17535438 Homo sapiens

I2D WIG001928 B Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway (more detail) 93 NA Homo sapiens

WikiPathway TAX025614 GO:0046513 biological process ceramide biosynthetic process The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoi (more detail) 41 NA Homo sapiens

GOA TAX022292 GO:0034062 molecular function 5' 3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis (more detail) 41 NA Homo sapiens

GOA TAX030991 GO:0097747 molecular function RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis (more detail) 41 NA Homo sapiens

GOA TAX017514 GO:0009112 biological process nucleobase metabolic process The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent (more detail) 41 NA Homo sapiens

GOA TAX019908 GO:0019985 biological process translesion synthesis The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DN (more detail) 41 NA Homo sapiens

GOA TAX034228 GO:1990391 cellular component DNA repair complex A protein complex involved in DNA repair processes including direct reversal, base excision repair, (more detail) 41 NA Homo sapiens

GOA WAG001229 Glutamate metabolism (more detail) 41 NA Homo sapiens

KEGG WAG000708 Regulation of activated PAK 2p34 by proteasome mediated degradation (more detail) 41 NA Homo sapiens

Reactome WAG000099 Host Interactions of HIV factors (more detail) 41 NA Homo sapiens

Reactome TAX001370 Genes annotated by the GO term GO:0004252. Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). (more detail) 41 NA Homo sapiens

MSigDB WAG001001 Nucleotide excision repair Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky D damage caused by com (more detail) 41 NA Homo sapiens

KEGG MEX002058 Genes associated with Kinase Inhibitor indirubin deriv. 7a Genes associated with Kinase Inhibitor indirubin deriv. 7a, curated by the Drug Signature Database ( (more detail) 41 25990557 Homo sapiens

DSigDB MEX001533 Genes associated with Kinase Inhibitor SureCN3470757 Genes associated with Kinase Inhibitor SureCN3470757, curated by the Drug Signature Database (DSigDB (more detail) 41 25990557 Homo sapiens

DSigDB WIG001710 Transcription of mRNA Transcription of mRNA (more detail) 41 NA Homo sapiens

Protein Lounge TAX015198 GO:0004520 molecular function endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal brea (more detail) 41 NA Homo sapiens

GOA MEX002347 Genes associated with Kinase Inhibitor 918505 84 7 Genes associated with Kinase Inhibitor 918505-84-7, curated by the Drug Signature Database (DSigDB). (more detail) 41 25990557 Homo sapiens

DSigDB WIG000063 Fanconi anemia pathway (more detail) 41 NA Homo sapiens

MSigDB IEI011448 Protein protein interactors of human gene RNF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF7 (SwissProt ID=Q (more detail) 57 17535438 Homo sapiens

I2D IEI008808 Protein protein interactors of human gene NFYA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFYA (SwissProt ID=P (more detail) 57 17535438 Homo sapiens

I2D MOX003291 Genes associated with Computational Drug Signature Sorafenib Genes associated with Computational Drug Signature Sorafenib, curated by the Drug Signature Database (more detail) 112 25990557 Homo sapiens

DSigDB FEX002791 StemCell Young03 142genes Table 2. Selected genes regulated by E2F1 and/or E2Fdb (more detail) 114 14562049 Homo sapiens

GeneSigDB TAX000854 Genes annotated by the GO term GO:0005694. A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. (more detail) 116 NA Homo sapiens

MSigDB IEI002199 Protein protein interactors of human gene CDC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC6 (SwissProt ID=Q (more detail) 48 17535438 Homo sapiens

I2D TAX000561 Genes annotated by the GO term GO:0016485. The posttranslational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations. (more detail) 48 NA Homo sapiens

MSigDB WIG001492 Estrogen mediated S Phase Entry Estrogen-mediated S-Phase Entry (more detail) 48 NA Homo sapiens

Protein Lounge IEI013366 Protein protein interactors of human gene TAL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAL1 (SwissProt ID=P (more detail) 54 17535438 Homo sapiens

I2D TAX027008 GO:0051438 biological process regulation of ubiquitin protein transferase activity Any process that modulates the frequency, rate or extent of ubiquitin transferase activity. (more detail) 54 NA Homo sapiens

GOA TAX032638 GO:1902750 biological process negative regulation of cell cycle G2/M phase transition Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle G2/M phase t (more detail) 54 NA Homo sapiens

GOA TAX023712 GO:0042177 biological process negative regulation of protein catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 120 NA Homo sapiens

GOA WIG000476 Arginine and proline metabolism (more detail) 51 NA Homo sapiens

MSigDB IEI001017 Protein protein interactors of human gene ATF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATF4 (SwissProt ID=P (more detail) 86 17535438 Homo sapiens

I2D IEI005592 Protein protein interactors of human gene GTF3C1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF3C1 (SwissProt ID (more detail) 72 17535438 Homo sapiens

I2D TAX020383 GO:0030216 biological process keratinocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte (more detail) 72 NA Homo sapiens

GOA FOX000218 Neighborhood of ST13 Neighborhood of ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) (more detail) 62 NA Homo sapiens

MSigDB WIG001237 Genes involved in Sphingolipid metabolism (more detail) 62 NA Homo sapiens

MSigDB FEX003489 Viral Cairo08 88genes Table S16. GSEA: Rank-Ordered Gene List for C1 versus C2 Using 88 Genes Upregulated by Myc as Descri (more detail) 79 19061838 Homo sapiens

GeneSigDB FOX000064 Neighborhood of PSME1 Neighborhood of PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) in the GCM e (more detail) 79 NA Homo sapiens

MSigDB IEI011065 Protein protein interactors of human gene RBM10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM10 (SwissProt ID= (more detail) 67 17535438 Homo sapiens

I2D IEI014229 Protein protein interactors of human gene TRIM25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM25 (SwissProt ID (more detail) 67 17535438 Homo sapiens

I2D WIG001197 Genes involved in Signaling by EGFR in Cancer (more detail) 105 NA Homo sapiens

MSigDB IEI014785 Protein protein interactors of human gene USP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP4 (SwissProt ID=Q (more detail) 81 17535438 Homo sapiens

I2D IEI008596 Protein protein interactors of human gene NBN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NBN (SwissProt ID=O6 (more detail) 81 17535438 Homo sapiens

I2D IEI013312 Protein protein interactors of human gene SYVN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SYVN1 (SwissProt ID= (more detail) 74 17535438 Homo sapiens

I2D TAX025526 GO:0046332 molecular function SMAD binding Interacting selectively and non-covalently with a SMAD signaling protein. (more detail) 74 NA Homo sapiens

GOA WAG001375 Vpu mediated degradation of CD4 (more detail) 44 NA Homo sapiens

Reactome WIG001397 Tacrolimus/Cyclosporine Pathway, Pharmacodynamics Stylized cell depicting the mechanism of action of tacrolimus and cyclosporine, as well as the candi (more detail) 44 NA Homo sapiens

PharmGKB WIG001291 Genes involved in Transcription coupled NER (TC NER) (more detail) 44 NA Homo sapiens

MSigDB MEX001577 Genes associated with Kinase Inhibitor 331771 20 1 Genes associated with Kinase Inhibitor 331771-20-1, curated by the Drug Signature Database (DSigDB). (more detail) 44 25990557 Homo sapiens

DSigDB WIG000037 C MYB transcription factor network (more detail) 83 NA Homo sapiens

MSigDB IEI014947 Protein protein interactors of human gene VTN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VTN (SwissProt ID=P0 (more detail) 94 17535438 Homo sapiens

I2D IEI015195 Protein protein interactors of human gene ZBTB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB1 (SwissProt ID= (more detail) 94 17535438 Homo sapiens

I2D IEI014630 Protein protein interactors of human gene UBXN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBXN1 (SwissProt ID= (more detail) 117 17535438 Homo sapiens

I2D IEI014742 Protein protein interactors of human gene USF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USF1 (SwissProt ID=P (more detail) 56 17535438 Homo sapiens

I2D IEI014089 Protein protein interactors of human gene TOP2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TOP2B (SwissProt ID= (more detail) 56 17535438 Homo sapiens

I2D IEI012679 Protein protein interactors of human gene SNIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNIP1 (SwissProt ID= (more detail) 56 17535438 Homo sapiens

I2D IEI000057 Protein protein interactors of human gene ABCF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABCF1 (SwissProt ID= (more detail) 56 17535438 Homo sapiens

I2D WIG000138 p53 pathway (more detail) 56 NA Homo sapiens

MSigDB WIG001816 G1 S Phase of the Cell Cycle The core engines that drive the progression through the eukaryotic cell cycle are complexes of cycli (more detail) 56 NA Homo sapiens

Spike WIG000614 RNA degradation The correct processing, quality control and turnover of cellular RNA molecules are critical to many (more detail) 56 NA Homo sapiens

MSigDB IEI007006 Protein protein interactors of human gene KRT10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KRT10 (SwissProt ID= (more detail) 121 17535438 Homo sapiens

I2D IEI006585 Protein protein interactors of human gene JAK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JAK2 (SwissProt ID=O (more detail) 123 17535438 Homo sapiens

I2D TAX019224 GO:0016798 molecular function hydrolase activity, acting on glycosyl bonds Catalysis of the hydrolysis of any glycosyl bond. (more detail) 123 NA Homo sapiens

GOA WIG001219 Genes involved in Signaling by SCF KIT (more detail) 76 NA Homo sapiens

MSigDB TAX020372 GO:0030204 biological process chondroitin sulfate metabolic process The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kD (more detail) 40 NA Homo sapiens

GOA TAX019100 GO:0016574 biological process histone ubiquitination The modification of histones by addition of ubiquitin groups. (more detail) 40 NA Homo sapiens

GOA TAX023850 GO:0042455 biological process ribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside i (more detail) 40 NA Homo sapiens

GOA TAX014787 GO:0003755 molecular function peptidyl prolyl cis trans isomerase activity Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). (more detail) 40 NA Homo sapiens

GOA PEX000271 Hormone recep: Ligand binding domain of nuclear hormone receptor This all helical domain is involved in binding the hormone in these receptors. (more detail) 40 NA Homo sapiens

Pfam TAX013403 GO:0000413 biological process protein peptidyl prolyl isomerization The modification of a protein by cis-trans isomerization of a proline residue. (more detail) 40 NA Homo sapiens

GOA WIG000934 Genes involved in Insulin receptor signalling cascade (more detail) 85 NA Homo sapiens

MSigDB IEI007845 Protein protein interactors of human gene MED16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED16 (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D TAX019167 GO:0016706 molecular function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2 oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduc (more detail) 47 NA Homo sapiens

GOA TAX000811 Genes annotated by the GO term GO:0006512. The cyclical process by which one or more ubiquitin moieties are added to (ubiquitination) and removed from (deubiquitination) a protein. (more detail) 47 NA Homo sapiens

MSigDB TAX013410 GO:0000428 cellular component DNA directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity. (more detail) 53 NA Homo sapiens

GOA IEI007708 Protein protein interactors of human gene MAPT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPT (SwissProt ID=P (more detail) 98 17535438 Homo sapiens

I2D TAX024477 GO:0043620 biological process regulation of DNA templated transcription in response to stress Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a st (more detail) 71 NA Homo sapiens

GOA IEI013337 Protein protein interactors of human gene TAF10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF10 (SwissProt ID= (more detail) 71 17535438 Homo sapiens

I2D MOX012175 Genes associated with Computational Drug Signature Dasatinib Genes associated with Computational Drug Signature Dasatinib, curated by the Drug Signature Database (more detail) 50 25990557 Homo sapiens

DSigDB TAX030618 GO:0090734 cellular component site of DNA damage A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins (more detail) 50 NA Homo sapiens

GOA TAX019572 GO:0019005 cellular component SCF ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form (more detail) 50 NA Homo sapiens

GOA IEI001263 Protein protein interactors of human gene BCAS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCAS2 (SwissProt ID= (more detail) 61 17535438 Homo sapiens

I2D IEI009891 Protein protein interactors of human gene PIAS4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIAS4 (SwissProt ID= (more detail) 102 17535438 Homo sapiens

I2D MOX000961 Genes associated with Computational Drug Signature Tanshinone I Genes associated with Computational Drug Signature Tanshinone I, curated by the Drug Signature Datab (more detail) 106 25990557 Homo sapiens

DSigDB IEI011088 Protein protein interactors of human gene RBM4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM4 (SwissProt ID=Q (more detail) 73 17535438 Homo sapiens

I2D WIG000495 Chronic myeloid leukemia Chronic myelogenous leukaemia (CML) is a biphasic disease, initiated by expression of the BCR/ABL fu (more detail) 73 NA Homo sapiens

MSigDB IEI013341 Protein protein interactors of human gene TAF15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF15 (SwissProt ID= (more detail) 110 17535438 Homo sapiens

I2D WIG001583 NF KappaB (p50/p65) Pathway NF-KappaB (p50/p65) Pathway (more detail) 91 NA Homo sapiens

Protein Lounge IEI008614 Protein protein interactors of human gene NCBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCBP1 (SwissProt ID= (more detail) 91 17535438 Homo sapiens

I2D IEI004324 Protein protein interactors of human gene ETS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ETS1 (SwissProt ID=P (more detail) 112 17535438 Homo sapiens

I2D IEI010632 Protein protein interactors of human gene PSMB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMB3 (SwissProt ID= (more detail) 82 17535438 Homo sapiens

I2D IEI014141 Protein protein interactors of human gene TPR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TPR (SwissProt ID=P1 (more detail) 82 17535438 Homo sapiens

I2D IEI009890 Protein protein interactors of human gene PIAS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIAS3 (SwissProt ID= (more detail) 63 17535438 Homo sapiens

I2D WIG001485 ErbB Family Pathway ErbB Family Pathway (more detail) 63 NA Homo sapiens

Protein Lounge TAX034376 GO:1990841 molecular function promoter specific chromatin binding Interacting selectively and non-covalently with a section of chromatin that is associated with gene (more detail) 43 NA Homo sapiens

GOA MEX002405 Genes associated with Kinase Inhibitor Vemurafenib Genes associated with Kinase Inhibitor Vemurafenib, curated by the Drug Signature Database (DSigDB). (more detail) 43 25990557 Homo sapiens

DSigDB MEX002155 Genes associated with Kinase Inhibitor AGN PC 04XSIT Genes associated with Kinase Inhibitor AGN-PC-04XSIT, curated by the Drug Signature Database (DSigDB (more detail) 43 25990557 Homo sapiens

DSigDB IEI004564 Protein protein interactors of human gene FANCA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FANCA (SwissProt ID= (more detail) 75 17535438 Homo sapiens

I2D IEI001204 Protein protein interactors of human gene BABAM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BABAM1 (SwissProt ID (more detail) 84 17535438 Homo sapiens

I2D MOX000732 Genes associated with Computational Drug Signature Spectrum 001666 Genes associated with Computational Drug Signature Spectrum_001666, curated by the Drug Signature Da (more detail) 84 25990557 Homo sapiens

DSigDB WAG001112 HIV 1 Transcription Initiation (more detail) 39 NA Homo sapiens

Reactome WAG000706 RNA Polymerase II Transcription Initiation And Promoter Clearance (more detail) 39 NA Homo sapiens

Reactome TAX017488 GO:0009072 biological process aromatic amino acid family metabolic process The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic (more detail) 39 NA Homo sapiens

GOA MEX002404 Genes associated with Kinase Inhibitor Axitinib Genes associated with Kinase Inhibitor Axitinib, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens

DSigDB WAG000124 Transcription of the HIV genome (more detail) 39 NA Homo sapiens

Reactome TAX013281 GO:0000154 biological process rRNA modification The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecu (more detail) 39 NA Homo sapiens

GOA WAG001123 RNA Polymerase II HIV 1 Promoter Escape (more detail) 39 NA Homo sapiens

Reactome MEX002035 Genes associated with Kinase Inhibitor GSK1838705A Genes associated with Kinase Inhibitor GSK1838705A, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens

DSigDB MEX002356 Genes associated with Kinase Inhibitor Dinaciclib Genes associated with Kinase Inhibitor Dinaciclib, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens

DSigDB TAX023120 GO:0035861 cellular component site of double strand break A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and r (more detail) 39 NA Homo sapiens

GOA WAG000279 Formation and Maturation of mRNA Transcript (more detail) 39 NA Homo sapiens

Reactome TAX013249 GO:0000096 biological process sulfur amino acid metabolic process The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, ho (more detail) 39 NA Homo sapiens

GOA TAX019485 GO:0018196 biological process peptidyl asparagine modification The modification of peptidyl-asparagine. (more detail) 39 NA Homo sapiens

GOA WAG001340 RNA Polymerase II Transcription Pre Initiation (more detail) 39 NA Homo sapiens

Reactome WAG000105 RNA Polymerase II Promoter Escape (more detail) 39 NA Homo sapiens

Reactome TAX016577 GO:0006757 biological process ATP generation from ADP The process of introducing a phosphate group into ADP, adenosine diphosphate, to produce ATP. (more detail) 39 NA Homo sapiens

GOA MEX001839 Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens

DSigDB MEX001834 Genes associated with Kinase Inhibitor 722544 51 6 Genes associated with Kinase Inhibitor 722544-51-6, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens

DSigDB TAX022207 GO:0033683 biological process nucleotide excision repair, DNA incision A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision oc (more detail) 39 NA Homo sapiens

GOA WAG001124 RNA Polymerase II Transcription Initiation (more detail) 39 NA Homo sapiens

Reactome MEX001905 Genes associated with Kinase Inhibitor Axitinib Genes associated with Kinase Inhibitor Axitinib, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens

DSigDB TAX017485 GO:0009069 biological process serine family amino acid metabolic process The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, (more detail) 39 NA Homo sapiens

GOA TAX022826 GO:0035337 biological process fatty acyl CoA metabolic process The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in whic (more detail) 39 NA Homo sapiens

GOA WAG000907 RNA Polymerase II Transcription (more detail) 39 NA Homo sapiens

Reactome WAG000905 HIV 1 Transcription Pre Initiation (more detail) 39 NA Homo sapiens

Reactome TAX017089 GO:0008146 molecular function sulfotransferase activity Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydro (more detail) 52 NA Homo sapiens

GOA IEI000908 Protein protein interactors of human gene ARNT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARNT (SwissProt ID=P (more detail) 52 17535438 Homo sapiens

I2D TAX027542 GO:0055029 cellular component nuclear DNA directed RNA polymerase complex A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity. (more detail) 52 NA Homo sapiens

GOA IEI003420 Protein protein interactors of human gene DDX39B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX39B (SwissProt ID (more detail) 86 17535438 Homo sapiens

I2D TAX000180 Genes annotated by the GO term GO:0006310. The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F duction. (more detail) 46 NA Homo sapiens

MSigDB FEX001679 Leukemia Messina10 53genes Table 3. PK Genes Distinctive of Each ALL Subgroup (more detail) 46 20564080 Homo sapiens

GeneSigDB TAX034906 GO:2000756 biological process regulation of peptidyl lysine acetylation Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation. (more detail) 60 NA Homo sapiens

GOA WIG000154 Regulation of retinoblastoma protein (more detail) 65 NA Homo sapiens

MSigDB TAX024475 GO:0043618 biological process regulation of transcription from RNA polymerase II promoter in response to stress Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II (more detail) 65 NA Homo sapiens

GOA TAX001454 Genes annotated by the GO term GO:0008270. Interacting selectively with zinc (Zn) ions. (more detail) 88 NA Homo sapiens

MSigDB TAX018842 GO:0016052 biological process carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of o (more detail) 107 NA Homo sapiens

GOA WIG001729 Yersinia Infection Yersinia Infection (more detail) 79 NA Homo sapiens

Protein Lounge MOX005152 Genes associated with Computational Drug Signature apigenin Genes associated with Computational Drug Signature apigenin, curated by the Drug Signature Database (more detail) 109 25990557 Homo sapiens

DSigDB IEI012257 Protein protein interactors of human gene SKIL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SKIL (SwissProt ID=P (more detail) 109 17535438 Homo sapiens

I2D WIG000810 Genes involved in Downstream signal transduction (more detail) 90 NA Homo sapiens

MSigDB IEI007522 Protein protein interactors of human gene LYAR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LYAR (SwissProt ID=Q (more detail) 115 17535438 Homo sapiens

I2D IEI011785 Protein protein interactors of human gene SAP18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SAP18 (SwissProt ID= (more detail) 115 17535438 Homo sapiens

I2D IEI009149 Protein protein interactors of human gene NUDT21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUDT21 (SwissProt ID (more detail) 119 17535438 Homo sapiens

I2D TAX026332 GO:0048754 biological process branching morphogenesis of an epithelial tube The process in which the anatomical structures of branches in an epithelial tube are generated and o (more detail) 121 NA Homo sapiens

GOA IEI002499 Protein protein interactors of human gene CHN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHN2 (SwissProt ID=P (more detail) 92 17535438 Homo sapiens

I2D IEI006617 Protein protein interactors of human gene JUND from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JUND (SwissProt ID=P (more detail) 57 17535438 Homo sapiens

I2D IEI011646 Protein protein interactors of human gene RRS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRS1 (SwissProt ID=Q (more detail) 57 17535438 Homo sapiens

I2D FOX000562 Genes in the cancer module 235 (more detail) 81 NA Homo sapiens

MSigDB TAX032326 GO:1901989 biological process positive regulation of cell cycle phase transition Any process that activates or increases the frequency, rate or extent of cell cycle phase transition (more detail) 81 NA Homo sapiens

GOA WEX000050 Insulin Signaling The genes related to insulin signaling (signaling pathways) in tumor using next-generation sequencer (more detail) 81 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas WAG000610 Chronic myeloid leukemia Chronic myelogenous leukemia (CML) origites in a pluripotent hematopoetic stem cell of the bone marr (more detail) 67 NA Homo sapiens

KEGG WIG001354 EGFR Inhibitor Pathway, Pharmacodynamics Model non-tissue specific cancer cell displaying genes that may be involved in the treatment using e (more detail) 67 NA Homo sapiens

PharmGKB IEI011064 Protein protein interactors of human gene RBL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBL2 (SwissProt ID=Q (more detail) 74 17535438 Homo sapiens

I2D IEI008633 Protein protein interactors of human gene NCOA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCOA2 (SwissProt ID= (more detail) 83 17535438 Homo sapiens

I2D TAX019263 GO:0016859 molecular function cis trans isomerase activity Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or (more detail) 42 NA Homo sapiens

GOA IEI007841 Protein protein interactors of human gene MED13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED13 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D TAX000556 Genes annotated by the GO term GO:0032446. A process by which one or more moieties of a small protein, such as ubiquitin or a ubiquitin like protein, are covalently attached to a target protein. (more detail) 42 NA Homo sapiens

MSigDB WIG001971 Eukaryotic Transcription Initiation Eukaryotic Transcription Initiation (more detail) 42 NA Homo sapiens

WikiPathway TAX013596 GO:0001047 molecular function core promoter binding Interacting selectively and non-covalently with the regulatory region composed of the transcription (more detail) 42 NA Homo sapiens

GOA IEI002665 Protein protein interactors of human gene CLNS1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLNS1A (SwissProt ID (more detail) 85 17535438 Homo sapiens

I2D IEI011531 Protein protein interactors of human gene RPL35 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL35 (SwissProt ID= (more detail) 85 17535438 Homo sapiens

I2D IEI014637 Protein protein interactors of human gene UBXN7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBXN7 (SwissProt ID= (more detail) 76 17535438 Homo sapiens

I2D WIG000499 Complement and coagulation cascades Blood coagulation is a series of coordinated and calcium-dependent proenzyme-to-serine protease conv (more detail) 69 NA Homo sapiens

MSigDB FEX000730 Breast Lin09 128genes Additional file 2. Probe sets on the pathways. The probe identifiers for the genes listed in the fiv (more detail) 69 19695104 Homo sapiens

GeneSigDB TAX019510 GO:0018279 biological process protein N linked glycosylation via asparagine The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine (more detail) 38 NA Homo sapiens

GOA TAX014838 GO:0003899 molecular function DNA directed 5' 3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA (more detail) 38 NA Homo sapiens

GOA TAX019306 GO:0016925 biological process protein sumoylation The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target pro (more detail) 38 NA Homo sapiens

GOA TAX030551 GO:0090503 biological process RNA phosphodiester bond hydrolysis, exonucleolytic The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds (more detail) 38 NA Homo sapiens

GOA TAX028981 GO:0070534 biological process protein K63 linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine (more detail) 38 NA Homo sapiens

GOA MEX002420 Genes associated with Kinase Inhibitor Nilotinib Genes associated with Kinase Inhibitor Nilotinib, curated by the Drug Signature Database (DSigDB). (more detail) 38 25990557 Homo sapiens

DSigDB MEX001769 Genes associated with Kinase Inhibitor GSK2606414 Genes associated with Kinase Inhibitor GSK2606414, curated by the Drug Signature Database (DSigDB). (more detail) 38 25990557 Homo sapiens

DSigDB WAG001300 Formation of RNA Pol II elongation complex (more detail) 38 NA Homo sapiens

Reactome MEX001100 Genes associated with Approved Drug afatinib Genes associated with Approved Drug afatinib, curated by the Drug Signature Database (DSigDB). (more detail) 38 25990557 Homo sapiens

DSigDB TAX016126 GO:0006096 biological process glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with (more detail) 38 NA Homo sapiens

GOA WAG001339 RNA Polymerase II Transcription Elongation (more detail) 38 NA Homo sapiens

Reactome TAX030766 GO:0097237 biological process cellular response to toxic substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 104 NA Homo sapiens

GOA MEX000848 Genes associated with Approved Drug doxorubicin hydrochloride Genes associated with Approved Drug doxorubicin hydrochloride, curated by the Drug Signature Databas (more detail) 104 25990557 Homo sapiens

DSigDB WIG001487 ErbB4 Pathway ErbB4 Pathway (more detail) 51 NA Homo sapiens

Protein Lounge IEI014277 Protein protein interactors of human gene TRIM8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM8 (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D IEI013749 Protein protein interactors of human gene TLE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLE1 (SwissProt ID=Q (more detail) 106 17535438 Homo sapiens

I2D IEI004012 Protein protein interactors of human gene EHMT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EHMT2 (SwissProt ID= (more detail) 106 17535438 Homo sapiens

I2D MOX000207 Genes associated with Computational Drug Signature 9,10 Phenanthrenequinone Genes associated with Computational Drug Signature 9,10-Phenanthrenequinone, curated by the Drug Sig (more detail) 106 25990557 Homo sapiens

DSigDB IEI014577 Protein protein interactors of human gene UBE2H from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2H (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D IEI002580 Protein protein interactors of human gene CKB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CKB (SwissProt ID=P1 (more detail) 87 17535438 Homo sapiens

I2D IEI010655 Protein protein interactors of human gene PSMD5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD5 (SwissProt ID= (more detail) 45 17535438 Homo sapiens

I2D TAX001195 Genes annotated by the GO term GO:0016810. Catalysis of the hydrolysis of any carbon nitrogen bond, C N, with the exception of peptide bonds. (more detail) 45 NA Homo sapiens

MSigDB MOX016641 Genes associated with Computational Drug Signature thymidine Genes associated with Computational Drug Signature thymidine, curated by the Drug Signature Database (more detail) 108 25990557 Homo sapiens

DSigDB IEI000562 Protein protein interactors of human gene ANAPC7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC7 (SwissProt ID (more detail) 48 17535438 Homo sapiens

I2D WAG001051 Signaling events mediated by HDAC Class I (more detail) 48 NA Homo sapiens

NCI-Nature Curated MEX001296 Genes associated with Kinase Inhibitor Ruboxistaurin Genes associated with Kinase Inhibitor Ruboxistaurin, curated by the Drug Signature Database (DSigDB (more detail) 48 25990557 Homo sapiens

DSigDB IEI008992 Protein protein interactors of human gene NPLOC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NPLOC4 (SwissProt ID (more detail) 78 17535438 Homo sapiens

I2D FOX000348 Neighborhood of PCNA Neighborhood of PCNA proliferating cell nuclear antigen in the MORF expression compendium (more detail) 78 NA Homo sapiens

MSigDB IEI010636 Protein protein interactors of human gene PSMB7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMB7 (SwissProt ID= (more detail) 71 17535438 Homo sapiens

I2D WIG000560 Melanoma Five distinct stages have been proposed in the evolution of melanoma on the basis of histological cr (more detail) 71 NA Homo sapiens

MSigDB WIG000156 Glucocorticoid receptor regulatory network (more detail) 80 NA Homo sapiens

MSigDB TAX029496 GO:0071482 biological process cellular response to light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 93 NA Homo sapiens

GOA FOX000809 Genes in the cancer module 57 (more detail) 56 NA Homo sapiens

MSigDB IEI014766 Protein protein interactors of human gene USP21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP21 (SwissProt ID= (more detail) 73 17535438 Homo sapiens

I2D IEI014629 Protein protein interactors of human gene UBTF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBTF (SwissProt ID=P (more detail) 61 17535438 Homo sapiens

I2D TAX015339 GO:0004714 molecular function transmembrane receptor protein tyrosine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to in (more detail) 61 NA Homo sapiens

GOA WIG000015 Coregulation of Androgen receptor activity (more detail) 61 NA Homo sapiens

MSigDB IEI011591 Protein protein interactors of human gene RPS27 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS27 (SwissProt ID= (more detail) 97 17535438 Homo sapiens

I2D IEI015252 Protein protein interactors of human gene ZC3HAV1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZC3HAV1 (SwissProt I (more detail) 53 17535438 Homo sapiens

I2D TAX027701 GO:0060147 biological process regulation of posttranscriptional gene silencing Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a (more detail) 53 NA Homo sapiens

GOA IEI010224 Protein protein interactors of human gene POLR2H from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2H (SwissProt ID (more detail) 53 17535438 Homo sapiens

I2D TAX028213 GO:0060966 biological process regulation of gene silencing by RNA Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing b (more detail) 53 NA Homo sapiens

GOA IEI014228 Protein protein interactors of human gene TRIM24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM24 (SwissProt ID (more detail) 53 17535438 Homo sapiens

I2D TAX032214 GO:1901658 biological process glycosyl compound catabolic process The chemical reactions and pathways resulting in the breakdown of glycosyl compound. (more detail) 41 NA Homo sapiens

GOA IEI014287 Protein protein interactors of human gene TRIP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIP4 (SwissProt ID= (more detail) 41 17535438 Homo sapiens

I2D MEX001356 Genes associated with Kinase Inhibitor Vemurafenib Genes associated with Kinase Inhibitor Vemurafenib, curated by the Drug Signature Database (DSigDB). (more detail) 41 25990557 Homo sapiens

DSigDB WIG000855 Genes involved in G2/M Checkpoints (more detail) 41 NA Homo sapiens

MSigDB WIG001003 Genes involved in mRNA Splicing Minor Pathway (more detail) 41 NA Homo sapiens

MSigDB TAX020965 GO:0031397 biological process negative regulation of protein ubiquitination Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiqui (more detail) 68 NA Homo sapiens

GOA MOX001084 Genes associated with Computational Drug Signature 1,10 phenanthroline Genes associated with Computational Drug Signature 1,10-phenanthroline, curated by the Drug Signatur (more detail) 107 25990557 Homo sapiens

DSigDB TAX023888 GO:0042542 biological process response to hydrogen peroxide Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 107 NA Homo sapiens

GOA IEI013011 Protein protein interactors of human gene SSBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SSBP1 (SwissProt ID= (more detail) 107 17535438 Homo sapiens

I2D TAX029338 GO:0071236 biological process cellular response to antibiotic Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 107 NA Homo sapiens

GOA MOX004142 Genes associated with Computational Drug Signature chitosamine Genes associated with Computational Drug Signature chitosamine, curated by the Drug Signature Databa (more detail) 86 25990557 Homo sapiens

DSigDB WAG000603 GnRH signaling pathway Godotropin-releasing hormone (GnRH) secretion from the hypothalamus acts upon its receptor in the an (more detail) 86 NA Homo sapiens

KEGG TAX014121 GO:0002221 biological process pattern recognition receptor signaling pathway Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) b (more detail) 113 NA Homo sapiens

GOA MAX001409 Genes up regulated in MEWO cells (melanoma) after 96 h of methionine [PubChem=876] deprivation. Methionine deprivation stress (MDS) eliminates mitotic activity in melanoma cells regardless of stag (more detail) 113 NA Homo sapiens

MSigDB IEI009137 Protein protein interactors of human gene NUDCD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUDCD3 (SwissProt ID (more detail) 115 17535438 Homo sapiens

I2D IEI012078 Protein protein interactors of human gene SF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SF1 (SwissProt ID=Q1 (more detail) 115 17535438 Homo sapiens

I2D FEX000357 Breast Martens05 117genes SuppTable 1. List of analyzed genes. The microarrays included 499 CpG sites from 117 genes. (more detail) 115 15899800 Homo sapiens

GeneSigDB IEI014069 Protein protein interactors of human gene TOB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TOB1 (SwissProt ID=P (more detail) 50 17535438 Homo sapiens

I2D TAX001341 Genes annotated by the GO term GO:0004713. Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. (more detail) 63 NA Homo sapiens

MSigDB WIG000053 Validated nuclear estrogen receptor alpha network (more detail) 63 NA Homo sapiens

MSigDB IEI007543 Protein protein interactors of human gene LZTR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LZTR1 (SwissProt ID= (more detail) 58 17535438 Homo sapiens

I2D MAX000377 Potential targets of MIR302A [GeneID=407028]. Oct4 and Sox2 are transcription factors required for pluripotency during early embryogenesis and for (more detail) 77 NA Homo sapiens

MSigDB WAG000068 Formation of HIV 1 elongation complex containing HIV 1 Tat (more detail) 37 NA Homo sapiens

Reactome WIG001739 Assembly of RNA Polymerase II Initiation Complex Assembly of RNA Polymerase-II Initiation Complex (more detail) 37 NA Homo sapiens

Protein Lounge TAX001128 Genes annotated by the GO term GO:0004197. Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; a cysteine residue is at the active center. (more detail) 37 NA Homo sapiens

MSigDB TAX016291 GO:0006383 biological process transcription by RNA polymerase III The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter. (more detail) 37 NA Homo sapiens

GOA TAX015209 GO:0004532 molecular function exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA mole (more detail) 37 NA Homo sapiens

GOA MEX001320 Genes associated with Kinase Inhibitor IKK Inhibitor VII Genes associated with Kinase Inhibitor IKK Inhibitor VII, curated by the Drug Signature Database (DS (more detail) 37 25990557 Homo sapiens

DSigDB TAX016239 GO:0006296 biological process nucleotide excision repair, DNA incision, 5' to lesion The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occ (more detail) 37 NA Homo sapiens

GOA MEX001785 Genes associated with Kinase Inhibitor Kinome 1194 Genes associated with Kinase Inhibitor Kinome_1194, curated by the Drug Signature Database (DSigDB). (more detail) 37 25990557 Homo sapiens

DSigDB MEX002186 Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 37 25990557 Homo sapiens

DSigDB MEX002100 Genes associated with Kinase Inhibitor Nilotinib Genes associated with Kinase Inhibitor Nilotinib, curated by the Drug Signature Database (DSigDB). (more detail) 37 25990557 Homo sapiens

DSigDB TAX022177 GO:0033619 biological process membrane protein proteolysis The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or e (more detail) 37 NA Homo sapiens

GOA IEI015118 Protein protein interactors of human gene XPC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XPC (SwissProt ID=Q0 (more detail) 44 17535438 Homo sapiens

I2D IEI006234 Protein protein interactors of human gene IGFBP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGFBP3 (SwissProt ID (more detail) 44 17535438 Homo sapiens

I2D TAX013614 GO:0001098 molecular function basal transcription machinery binding Interacting selectively and non-covalently with the basal transcription machinery which is composed (more detail) 44 NA Homo sapiens

GOA TAX013615 GO:0001099 molecular function basal RNA polymerase II transcription machinery binding Interacting selectively and non-covalently with the basal transcription machinery for RNA polymerase (more detail) 44 NA Homo sapiens

GOA IEI012865 Protein protein interactors of human gene SPEN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPEN (SwissProt ID=Q (more detail) 47 17535438 Homo sapiens

I2D IEI008831 Protein protein interactors of human gene NIFK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NIFK (SwissProt ID=Q (more detail) 47 17535438 Homo sapiens

I2D IEI012255 Protein protein interactors of human gene SKI from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SKI (SwissProt ID=P1 (more detail) 47 17535438 Homo sapiens

I2D IEI014772 Protein protein interactors of human gene USP28 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP28 (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D IEI007797 Protein protein interactors of human gene MCM4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCM4 (SwissProt ID=P (more detail) 90 17535438 Homo sapiens

I2D WEX000061 Melanoma The genes related to melanoma (physiology & disease) in tumor using next-generation sequencer (NGS) (more detail) 70 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI013149 Protein protein interactors of human gene STRAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STRAP (SwissProt ID= (more detail) 79 17535438 Homo sapiens

I2D WEX000032 FoxO Signaling The genes related to foxo signaling (signaling pathways) in tumor, immune using next-generation sequ (more detail) 79 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas MOX001488 Genes associated with Computational Drug Signature ellipticine Genes associated with Computational Drug Signature ellipticine, curated by the Drug Signature Databa (more detail) 92 25990557 Homo sapiens

DSigDB IEI014708 Protein protein interactors of human gene UPF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UPF2 (SwissProt ID=Q (more detail) 94 17535438 Homo sapiens

I2D IEI012581 Protein protein interactors of human gene SMAD5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMAD5 (SwissProt ID= (more detail) 65 17535438 Homo sapiens

I2D WAG001431 Melanoma Melanoma is a form of skin cancer that has a poor prognosis and which is on the rise in Western popu (more detail) 65 NA Homo sapiens

KEGG IEI011990 Protein protein interactors of human gene SENP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SENP3 (SwissProt ID= (more detail) 55 17535438 Homo sapiens

I2D TAX021869 GO:0032922 biological process circadian regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression such that an expression (more detail) 55 NA Homo sapiens

GOA IEI002855 Protein protein interactors of human gene COPS7A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COPS7A (SwissProt ID (more detail) 55 17535438 Homo sapiens

I2D IEI014676 Protein protein interactors of human gene UHRF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UHRF2 (SwissProt ID= (more detail) 55 17535438 Homo sapiens

I2D WEX000102 TNF Signaling The genes related to tnf signaling (immune response) in tumor, immune using next-generation sequence (more detail) 96 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI010658 Protein protein interactors of human gene PSMD8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD8 (SwissProt ID= (more detail) 72 17535438 Homo sapiens

I2D MOX000283 Genes associated with Computational Drug Signature baicalein Genes associated with Computational Drug Signature baicalein, curated by the Drug Signature Database (more detail) 72 25990557 Homo sapiens

DSigDB IEI012690 Protein protein interactors of human gene SNRPA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRPA (SwissProt ID= (more detail) 98 17535438 Homo sapiens

I2D FAX000298 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif KCCGNSWTTT. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif KCCGNSWTTT. (more detail) 98 NA Homo sapiens

MSigDB IEI003892 Protein protein interactors of human gene E2F4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene E2F4 (SwissProt ID=Q (more detail) 60 17535438 Homo sapiens

I2D IEI009831 Protein protein interactors of human gene PHB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHB2 (SwissProt ID=Q (more detail) 100 17535438 Homo sapiens

I2D IEI000708 Protein protein interactors of human gene APBB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APBB1 (SwissProt ID= (more detail) 83 17535438 Homo sapiens

I2D IEI008331 Protein protein interactors of human gene MTHFD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTHFD1 (SwissProt ID (more detail) 102 17535438 Homo sapiens

I2D TAX027209 GO:0051817 biological process modification of morphology or physiology of other organism involved in symbiotic interaction The process in which an organism effects a change in the structure or processes of a second organism (more detail) 104 NA Homo sapiens

GOA IEI005758 Protein protein interactors of human gene HDAC9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDAC9 (SwissProt ID= (more detail) 104 17535438 Homo sapiens

I2D TAX016854 GO:0007219 biological process Notch signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to the receptor No (more detail) 104 NA Homo sapiens

GOA IEI004417 Protein protein interactors of human gene FAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAF1 (SwissProt ID=Q (more detail) 104 17535438 Homo sapiens

I2D MOX000279 Genes associated with Computational Drug Signature kaempferol Genes associated with Computational Drug Signature kaempferol, curated by the Drug Signature Databas (more detail) 104 25990557 Homo sapiens

DSigDB FEX002656 Prostate Chandran07 154genes Table 4 GO and pathway annotation of genes and pathways altered in metastatic prostate cancer (more detail) 106 17430594 Homo sapiens

GeneSigDB MOX017620 Genes associated with Computational Drug Signature daunorubicin Genes associated with Computational Drug Signature daunorubicin, curated by the Drug Signature Datab (more detail) 106 25990557 Homo sapiens

DSigDB FOX000282 Neighborhood of DNMT1 Neighborhood of DNMT1 DNA (cytosine-5-)-methyltransferase 1 in the MORF expression compendium (more detail) 108 NA Homo sapiens

MSigDB MEX000156 Genes associated with Approved Drug hexachlorophene Genes associated with Approved Drug hexachlorophene, curated by the Drug Signature Database (DSigDB) (more detail) 110 25990557 Homo sapiens

DSigDB IEI012012 Protein protein interactors of human gene SERBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERBP1 (SwissProt ID (more detail) 112 17535438 Homo sapiens

I2D IEI003705 Protein protein interactors of human gene DNMT3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNMT3A (SwissProt ID (more detail) 52 17535438 Homo sapiens

I2D WAG000614 Folate biosynthesis (more detail) 52 NA Homo sapiens

KEGG IEI009058 Protein protein interactors of human gene NRIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NRIP1 (SwissProt ID= (more detail) 67 17535438 Homo sapiens

I2D IEI002655 Protein protein interactors of human gene CLK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLK2 (SwissProt ID=P (more detail) 67 17535438 Homo sapiens

I2D WIG001172 Genes involved in RNA Polymerase II Transcription Pre Initiation And Promoter Opening (more detail) 40 NA Homo sapiens

MSigDB IEI000131 Protein protein interactors of human gene ACIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACIN1 (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D IEI013485 Protein protein interactors of human gene TCERG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCERG1 (SwissProt ID (more detail) 76 17535438 Homo sapiens

I2D IEI011520 Protein protein interactors of human gene RPL26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL26 (SwissProt ID= (more detail) 76 17535438 Homo sapiens

I2D TAX020813 GO:0031100 biological process animal organ regeneration The regrowth of a lost or destroyed animal organ. (more detail) 76 NA Homo sapiens

GOA IEI000324 Protein protein interactors of human gene ADRM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADRM1 (SwissProt ID= (more detail) 62 17535438 Homo sapiens

I2D IEI011201 Protein protein interactors of human gene RFC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RFC2 (SwissProt ID=P (more detail) 57 17535438 Homo sapiens

I2D WIG001132 Genes involved in Regulation of Apoptosis (more detail) 57 NA Homo sapiens

MSigDB WIG000462 Acute myeloid leukemia Two major types of genetic events are crucial for the molecular pathogenesis of acute myeloid leukem (more detail) 57 NA Homo sapiens

MSigDB MOX000557 Genes associated with Computational Drug Signature 7,8 Benzoflavone Genes associated with Computational Drug Signature 7,8-Benzoflavone, curated by the Drug Signature D (more detail) 89 25990557 Homo sapiens

DSigDB TAX000436 Genes annotated by the GO term GO:0055086. The chemical reactions and pathways involving nucleobases, nucleosides and nucleotides. (more detail) 49 NA Homo sapiens

MSigDB FEX002545 pancreas Miyake06 52genes Table 1 Fifty-two genes were examined using customized cDNA array (more detail) 49 16699793 Homo sapiens

GeneSigDB IEI011595 Protein protein interactors of human gene RPS29 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS29 (SwissProt ID= (more detail) 69 17535438 Homo sapiens

I2D FOX000233 Neighborhood of XRCC5 Neighborhood of XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double (more detail) 69 NA Homo sapiens

MSigDB WIG001925 Neural Crest Differentiation Neural Crest Differentiation (more detail) 91 NA Homo sapiens

WikiPathway IEI000136 Protein protein interactors of human gene ACLY from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACLY (SwissProt ID=P (more detail) 91 17535438 Homo sapiens

I2D TAX026515 GO:0050681 molecular function androgen receptor binding Interacting selectively and non-covalently with an androgen receptor. (more detail) 43 NA Homo sapiens

GOA IEI010115 Protein protein interactors of human gene PLRG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLRG1 (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D WAG000387 Thiamine metabolism (more detail) 43 NA Homo sapiens

KEGG TAX024647 GO:0044257 biological process cellular protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. (more detail) 36 NA Homo sapiens

GOA TAX024887 GO:0045005 biological process DNA dependent DNA replication maintenance of fidelity A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately (more detail) 36 NA Homo sapiens

GOA TAX019287 GO:0016891 molecular function endoribonuclease activity, producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks t (more detail) 36 NA Homo sapiens

GOA TAX014909 GO:0004003 molecular function ATP dependent DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DN (more detail) 36 NA Homo sapiens

GOA TAX020842 GO:0031145 biological process anaphase promoting complex dependent catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 36 NA Homo sapiens

GOA TAX019113 GO:0016592 cellular component mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA poly (more detail) 36 NA Homo sapiens

GOA WAG000333 mRNA Splicing Minor Pathway (more detail) 36 NA Homo sapiens

Reactome WIG000504 DNA replication A complex network of interacting proteins and enzymes is required for DNA replication. Generally, DN (more detail) 36 NA Homo sapiens

MSigDB MEX001454 Genes associated with Kinase Inhibitor Quercetagetin Genes associated with Kinase Inhibitor Quercetagetin, curated by the Drug Signature Database (DSigDB (more detail) 36 25990557 Homo sapiens

DSigDB FOX000850 Genes in the cancer module 91 (more detail) 36 NA Homo sapiens

MSigDB MEX001590 Genes associated with Kinase Inhibitor BMS 387032 Genes associated with Kinase Inhibitor BMS-387032, curated by the Drug Signature Database (DSigDB). (more detail) 36 25990557 Homo sapiens

DSigDB MEX001723 Genes associated with Kinase Inhibitor SureCN10127740 Genes associated with Kinase Inhibitor SureCN10127740, curated by the Drug Signature Database (DSigD (more detail) 36 25990557 Homo sapiens

DSigDB WIG000850 Genes involved in FRS2 mediated cascade (more detail) 36 NA Homo sapiens

MSigDB WIG000619 Sphingolipid metabolism (more detail) 36 NA Homo sapiens

MSigDB WIG000120 Validated targets of C MYC transcriptional activation (more detail) 78 NA Homo sapiens

MSigDB IEI013349 Protein protein interactors of human gene TAF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF4 (SwissProt ID=O (more detail) 46 17535438 Homo sapiens

I2D WIG000364 Keratinocyte Differentiation The epidermis, which provides a protective barrier that undergoes a constant renewal, is a multi-lay (more detail) 46 NA Homo sapiens

MSigDB TAX020199 GO:0022627 cellular component cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol. (more detail) 46 NA Homo sapiens

GOA WIG001778 B Cell Receptor Complex B-Cell Receptor Complex (more detail) 93 NA Homo sapiens

Protein Lounge MOX004271 Genes associated with Computational Drug Signature lovastatin Genes associated with Computational Drug Signature lovastatin, curated by the Drug Signature Databas (more detail) 95 25990557 Homo sapiens

DSigDB WIG000712 Genes involved in Asparagine N linked glycosylation (more detail) 80 NA Homo sapiens

MSigDB TAX033707 GO:1904949 cellular component ATPase complex A protein complex which is capable of ATPase activity. (more detail) 97 NA Homo sapiens

GOA IEI001885 Protein protein interactors of human gene CCAR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCAR2 (SwissProt ID= (more detail) 97 17535438 Homo sapiens

I2D TAX027304 GO:0051983 biological process regulation of chromosome segregation Any process that modulates the frequency, rate or extent of chromosome segregation, the process in w (more detail) 97 NA Homo sapiens

GOA TAX024378 GO:0043467 biological process regulation of generation of precursor metabolites and energy Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 97 NA Homo sapiens

GOA WIG001628 PI3K Signaling in B Lymphocyte PI3K Signaling in B-Lymphocyte (more detail) 97 NA Homo sapiens

Protein Lounge IEI011060 Protein protein interactors of human gene RBFOX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBFOX2 (SwissProt ID (more detail) 64 17535438 Homo sapiens

I2D MOX004134 Genes associated with Computational Drug Signature Gallic acid Genes associated with Computational Drug Signature Gallic acid, curated by the Drug Signature Databa (more detail) 64 25990557 Homo sapiens

DSigDB WIG001080 Genes involved in PI 3K cascade (more detail) 54 NA Homo sapiens

MSigDB WEX000001 Amino Acid Synthesis & Transport The genes related to amino acid synthesis & transport (metabolism) in tumor, immune, stroma using ne (more detail) 54 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI001287 Protein protein interactors of human gene BCL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCL3 (SwissProt ID=P (more detail) 54 17535438 Homo sapiens

I2D TAX022716 GO:0035065 biological process regulation of histone acetylation Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a his (more detail) 54 NA Homo sapiens

GOA WIG000537 GnRH signaling pathway Gonadotropin-releasing hormone (GnRH) secretion from the hypothalamus acts upon its receptor in the (more detail) 101 NA Homo sapiens

MSigDB TAX032048 GO:1901216 biological process positive regulation of neuron death Any process that activates or increases the frequency, rate or extent of neuron death. (more detail) 82 NA Homo sapiens

GOA IEI013969 Protein protein interactors of human gene TMPO from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TMPO (SwissProt ID=P (more detail) 82 17535438 Homo sapiens

I2D IEI013010 Protein protein interactors of human gene SSB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SSB (SwissProt ID=P0 (more detail) 109 17535438 Homo sapiens

I2D WEX000095 TCR Signaling The genes related to tcr signaling (adaptive immunity) in immune using next-generation sequencer (NG (more detail) 109 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas MOX000787 Genes associated with Computational Drug Signature sulforaphane Genes associated with Computational Drug Signature sulforaphane, curated by the Drug Signature Datab (more detail) 109 25990557 Homo sapiens

DSigDB TAX000367 Genes annotated by the GO term GO:0000279. Progression through M phase, the part of the cell cycle comprising nuclear division. (more detail) 111 NA Homo sapiens

MSigDB IEI004362 Protein protein interactors of human gene EXOSC10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXOSC10 (SwissProt I (more detail) 73 17535438 Homo sapiens

I2D IEI011052 Protein protein interactors of human gene RBBP5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBBP5 (SwissProt ID= (more detail) 66 17535438 Homo sapiens

I2D IEI007750 Protein protein interactors of human gene MAVS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAVS (SwissProt ID=Q (more detail) 86 17535438 Homo sapiens

I2D IEI014988 Protein protein interactors of human gene WDR18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR18 (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D IEI014094 Protein protein interactors of human gene TOPORS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TOPORS (SwissProt ID (more detail) 51 17535438 Homo sapiens

I2D TAX020489 GO:0030374 molecular function nuclear receptor transcription coactivator activity The function of a transcription cofactor that activates transcription in conjuction with a ligand-de (more detail) 51 NA Homo sapiens

GOA FEX000743 Breast Speers09 52genes OverExpressedNegativeCancer Supplementary Table 2: Kinases overexpressed in ER?negative breast cancer (more detail) 51 19808870 Homo sapiens

GeneSigDB IEI004250 Protein protein interactors of human gene ERCC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERCC3 (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D IEI012873 Protein protein interactors of human gene SPI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPI1 (SwissProt ID=P (more detail) 75 17535438 Homo sapiens

I2D TAX021952 GO:0033045 biological process regulation of sister chromatid segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation. (more detail) 75 NA Homo sapiens

GOA TAX020292 GO:0030097 biological process hemopoiesis The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tiss (more detail) 88 NA Homo sapiens

GOA TAX021560 GO:0032451 molecular function demethylase activity Catalysis of the removal of a methyl group from a substrate. (more detail) 39 NA Homo sapiens

GOA FEX000672 Breast Reyal08 41genes Additional file 6 An Excel file containing a figure showing the log-rank test P value on the Chin?Lo (more detail) 39 19014521 Homo sapiens

GeneSigDB TAX000570 Genes annotated by the GO term GO:0016567. The process by which one or more ubiquitin moieties are added to a protein. (more detail) 39 NA Homo sapiens

MSigDB FOX000438 Genes in the cancer module 109 (more detail) 39 NA Homo sapiens

MSigDB TAX028648 GO:0061982 biological process meiosis I cell cycle process A process that contributes to the first meiotic division. The first meiotic division is the reductiv (more detail) 61 NA Homo sapiens

GOA WIG002013 Notch Signaling Pathway Notch Signaling Pathway (more detail) 61 NA Homo sapiens

WikiPathway WIG001918 Leptin signaling pathway Leptin signaling pathway (more detail) 61 NA Homo sapiens

WikiPathway IEI002271 Protein protein interactors of human gene CDKN1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDKN1B (SwissProt ID (more detail) 90 17535438 Homo sapiens

I2D MOX004185 Genes associated with Computational Drug Signature hexachlorophene Genes associated with Computational Drug Signature hexachlorophene, curated by the Drug Signature Da (more detail) 90 25990557 Homo sapiens

DSigDB IEI002248 Protein protein interactors of human gene CDK19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK19 (SwissProt ID= (more detail) 56 17535438 Homo sapiens

I2D TAX026379 GO:0048863 biological process stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A (more detail) 56 NA Homo sapiens

GOA IEI006616 Protein protein interactors of human gene JUNB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JUNB (SwissProt ID=P (more detail) 56 17535438 Homo sapiens

I2D IEI002710 Protein protein interactors of human gene CNBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNBP (SwissProt ID=P (more detail) 68 17535438 Homo sapiens

I2D TAX025818 GO:0046934 molecular function phosphatidylinositol 4,5 bisphosphate 3 kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl- (more detail) 68 NA Homo sapiens

GOA TAX013230 GO:0000049 molecular function tRNA binding Interacting selectively and non-covalently with transfer RNA. (more detail) 48 NA Homo sapiens

GOA TAX000545 Genes annotated by the GO term GO:0065004. The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein DNA complex. (more detail) 48 NA Homo sapiens

MSigDB TAX016152 GO:0006140 biological process regulation of nucleotide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 92 NA Homo sapiens

GOA MOX016819 Genes associated with Computational Drug Signature Erlotinib Genes associated with Computational Drug Signature Erlotinib, curated by the Drug Signature Database (more detail) 94 25990557 Homo sapiens

DSigDB MOX017157 Genes associated with Computational Drug Signature Gefitinib Genes associated with Computational Drug Signature Gefitinib, curated by the Drug Signature Database (more detail) 94 25990557 Homo sapiens

DSigDB IEI011603 Protein protein interactors of human gene RPS6KA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS6KA1 (SwissProt I (more detail) 94 17535438 Homo sapiens

I2D WIG001990 IL 2 Signaling pathway IL-2 Signaling pathway (more detail) 42 NA Homo sapiens

WikiPathway WIG001587 AlzheimerÃ‚Â¿s Disease Pathway AlzheimerÃ‚Â¿s Disease Pathway (more detail) 42 NA Homo sapiens

Protein Lounge IEI012687 Protein protein interactors of human gene SNRNP40 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRNP40 (SwissProt I (more detail) 45 17535438 Homo sapiens

I2D MEX001976 Genes associated with Kinase Inhibitor SureCN186278 Genes associated with Kinase Inhibitor SureCN186278, curated by the Drug Signature Database (DSigDB) (more detail) 45 25990557 Homo sapiens

DSigDB TAX022690 GO:0035004 molecular function phosphatidylinositol 3 kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. (more detail) 79 NA Homo sapiens

GOA IEI011655 Protein protein interactors of human gene RSL1D1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RSL1D1 (SwissProt ID (more detail) 79 17535438 Homo sapiens

I2D WIG000659 Genes involved in Activation of ATR in response to replication stress (more detail) 35 NA Homo sapiens

MSigDB TAX016588 GO:0006778 biological process porphyrin containing compound metabolic process The chemical reactions and pathways involving any member of a large group of derivatives or analogs (more detail) 35 NA Homo sapiens

GOA MEX002385 Genes associated with Kinase Inhibitor R547 Genes associated with Kinase Inhibitor R547, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens

DSigDB MEX001512 Genes associated with Kinase Inhibitor Doramapimod Genes associated with Kinase Inhibitor Doramapimod, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens

DSigDB MEX001696 Genes associated with Kinase Inhibitor Ki20227 Genes associated with Kinase Inhibitor Ki20227, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens

DSigDB TAX019030 GO:0016445 biological process somatic diversification of immunoglobulins The somatic process that results in the generation of sequence diversity of immunoglobulins. (more detail) 35 NA Homo sapiens

GOA TAX021088 GO:0031638 biological process zymogen activation The proteolytic processing of an inactive enzyme to an active form. (more detail) 35 NA Homo sapiens

GOA MEX002126 Genes associated with Kinase Inhibitor 841290 80 0 Genes associated with Kinase Inhibitor 841290-80-0, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens

DSigDB TAX013350 GO:0000291 biological process nuclear transcribed mRNA catabolic process, exonucleolytic The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-t (more detail) 35 NA Homo sapiens

GOA TAX023894 GO:0042558 biological process pteridine containing compound metabolic process The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyri (more detail) 35 NA Homo sapiens

GOA TAX024150 GO:0043094 biological process cellular metabolic compound salvage Any process which produces a useful metabolic compound from derivatives of it without de novo synthe (more detail) 35 NA Homo sapiens

GOA MEX001485 Genes associated with Kinase Inhibitor Syk Inhibitor Genes associated with Kinase Inhibitor Syk Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 35 25990557 Homo sapiens

DSigDB TAX013556 GO:0000959 biological process mitochondrial RNA metabolic process The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occu (more detail) 35 NA Homo sapiens

GOA TAX019029 GO:0016444 biological process somatic cell DNA recombination Recombination occurring within or between DNA molecules in somatic cells. (more detail) 35 NA Homo sapiens

GOA TAX014303 GO:0002562 biological process somatic diversification of immune receptors via germline recombination within a single locus The process in which immune receptor genes are diversified through recombination of the germline gen (more detail) 35 NA Homo sapiens

GOA TAX001390 Genes annotated by the GO term GO:0003704. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II. (more detail) 35 NA Homo sapiens

MSigDB WAG000527 Tat mediated elongation of the HIV 1 transcript (more detail) 35 NA Homo sapiens

Reactome TAX016561 GO:0006734 biological process NADH metabolic process The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a co (more detail) 35 NA Homo sapiens

GOA WAG000718 Processing of Capped Intron Containing Pre mRNA (more detail) 35 NA Homo sapiens

Reactome IEI008658 Protein protein interactors of human gene NDRG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NDRG1 (SwissProt ID= (more detail) 100 17535438 Homo sapiens

I2D TAX020384 GO:0030217 biological process T cell differentiation The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cel (more detail) 100 NA Homo sapiens

GOA IEI011525 Protein protein interactors of human gene RPL29 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL29 (SwissProt ID= (more detail) 70 17535438 Homo sapiens

I2D IEI015009 Protein protein interactors of human gene WDR48 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR48 (SwissProt ID= (more detail) 70 17535438 Homo sapiens

I2D IEI010539 Protein protein interactors of human gene PRPF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRPF4 (SwissProt ID= (more detail) 70 17535438 Homo sapiens

I2D IEI003706 Protein protein interactors of human gene DNMT3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNMT3B (SwissProt ID (more detail) 70 17535438 Homo sapiens

I2D IEI004596 Protein protein interactors of human gene FAU from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAU (SwissProt ID=P3 (more detail) 70 17535438 Homo sapiens

I2D IEI002941 Protein protein interactors of human gene CPSF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CPSF6 (SwissProt ID= (more detail) 104 17535438 Homo sapiens

I2D TAX026306 GO:0048705 biological process skeletal system morphogenesis The process in which the anatomical structures of the skeleton are generated and organized. (more detail) 104 NA Homo sapiens

GOA IEI011010 Protein protein interactors of human gene RASA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RASA1 (SwissProt ID= (more detail) 106 17535438 Homo sapiens

I2D FOX000410 Neighborhood of TERF2IP Neighborhood of TERF2IP telomeric repeat binding factor 2, interacting protein in the MORF expressi (more detail) 108 NA Homo sapiens

MSigDB WIG001505 FLT3 Signaling FLT3 Signaling (more detail) 53 NA Homo sapiens

Protein Lounge TAX022693 GO:0035019 biological process somatic stem cell population maintenance Any process by which an organism retains a population of somatic stem cells, undifferentiated cells (more detail) 53 NA Homo sapiens

GOA TAX028708 GO:0070063 molecular function RNA polymerase binding Interacting selectively and non-covalently with an RNA polymerase molecule or complex. (more detail) 53 NA Homo sapiens

GOA IEI007648 Protein protein interactors of human gene MAP2K4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP2K4 (SwissProt ID (more detail) 58 17535438 Homo sapiens

I2D FOX000334 Neighborhood of MSH2 Neighborhood of MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) in the MORF expres (more detail) 58 NA Homo sapiens

MSigDB TAX016673 GO:0006911 biological process phagocytosis, engulfment The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic ce (more detail) 85 NA Homo sapiens

GOA WAG001620 Complement and coagulation cascades The complement system is a proteolytic cascade in blood plasma and a mediator of inte immunity, a no (more detail) 65 NA Homo sapiens

KEGG IEI000479 Protein protein interactors of human gene ALDOA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ALDOA (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D IEI006229 Protein protein interactors of human gene IGF2BP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGF2BP3 (SwissProt I (more detail) 87 17535438 Homo sapiens

I2D WIG000043 E2F transcription factor network (more detail) 74 NA Homo sapiens

MSigDB TAX028211 GO:0060964 biological process regulation of gene silencing by miRNA Any process that modulates the rate, frequency, or extent of the downregulation of gene expression t (more detail) 50 NA Homo sapiens

GOA IEI010223 Protein protein interactors of human gene POLR2G from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2G (SwissProt ID (more detail) 50 17535438 Homo sapiens

I2D FEX000745 Breast Speers09 52genes IDKinasesOverExpressed Table 2. Kinases identified in analysis as most highly overexpressed in ER-negative tumors (more detail) 50 19808870 Homo sapiens

GeneSigDB TAX026886 GO:0051234 biological process establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering (more detail) 4136 NA Homo sapiens

GOA IEI014261 Protein protein interactors of human gene TRIM55 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM55 (SwissProt ID (more detail) 91 17535438 Homo sapiens

I2D IEI008646 Protein protein interactors of human gene NCSTN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCSTN (SwissProt ID= (more detail) 91 17535438 Homo sapiens

I2D IEI010286 Protein protein interactors of human gene POU5F1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POU5F1 (SwissProt ID (more detail) 67 17535438 Homo sapiens

I2D IEI012961 Protein protein interactors of human gene SREBF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SREBF2 (SwissProt ID (more detail) 93 17535438 Homo sapiens

I2D WIG001783 BCR Pathway BCR Pathway (more detail) 93 NA Homo sapiens

Protein Lounge MAX002397 Genes whose promoters were bound by E2F1 and E2F4 [GeneID=1869;1874] in the primary fibroblasts WI 38, by ChIP on chip assay. The E2F transcription factor family is known to play a key role in the timely expression of genes re (more detail) 55 NA Homo sapiens

MSigDB MOX013743 Genes associated with Computational Drug Signature mitoxantrone Genes associated with Computational Drug Signature mitoxantrone, curated by the Drug Signature Datab (more detail) 55 25990557 Homo sapiens

DSigDB WIG000066 FGF signaling pathway (more detail) 55 NA Homo sapiens

MSigDB IEI009795 Protein protein interactors of human gene PGAM5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PGAM5 (SwissProt ID= (more detail) 55 17535438 Homo sapiens

I2D WIG000019 ATR signaling pathway (more detail) 38 NA Homo sapiens

MSigDB FOX000226 Neighborhood of TPT1 Neighborhood of TPT1 tumor protein, translationally-controlled 1 in the GNF2 expression compendium (more detail) 38 NA Homo sapiens

MSigDB TAX019362 GO:0017069 molecular function snRNA binding Interacting selectively and non-covalently with a small nuclear RNA (snRNA). (more detail) 38 NA Homo sapiens

GOA IEI007847 Protein protein interactors of human gene MED18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED18 (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D MOX016938 Genes associated with Computational Drug Signature luteolin Genes associated with Computational Drug Signature luteolin, curated by the Drug Signature Database (more detail) 95 25990557 Homo sapiens

DSigDB FEX001336 Leukemia Passioura05 105genes Table S6 - Genes down-regulated by N-rasG13R in K562 cells (more detail) 97 15705876 Homo sapiens

GeneSigDB IEI010542 Protein protein interactors of human gene PRPF4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRPF4B (SwissProt ID (more detail) 47 17535438 Homo sapiens

I2D TAX014780 GO:0003727 molecular function single stranded RNA binding Interacting selectively and non-covalently with single-stranded RNA. (more detail) 78 NA Homo sapiens

GOA IEI007199 Protein protein interactors of human gene LDHB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LDHB (SwissProt ID=P (more detail) 101 17535438 Homo sapiens

I2D TAX035112 GO:2001237 biological process negative regulation of extrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic sig (more detail) 103 NA Homo sapiens

GOA IEI007409 Protein protein interactors of human gene LRPPRC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRPPRC (SwissProt ID (more detail) 105 17535438 Homo sapiens

I2D TAX013385 GO:0000381 biological process regulation of alternative mRNA splicing, via spliceosome Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs. (more detail) 44 NA Homo sapiens

GOA TAX021776 GO:0032784 biological process regulation of DNA templated transcription, elongation Any process that modulates the frequency, rate or extent of transcription elongation, the extension (more detail) 44 NA Homo sapiens

GOA MEX002353 Genes associated with Kinase Inhibitor BRD K72636697 001 01 5 Genes associated with Kinase Inhibitor BRD-K72636697-001-01-5, curated by the Drug Signature Databas (more detail) 44 25990557 Homo sapiens

DSigDB IEI003647 Protein protein interactors of human gene DNAJA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJA2 (SwissProt ID (more detail) 80 17535438 Homo sapiens

I2D IEI012081 Protein protein interactors of human gene SF3A3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SF3A3 (SwissProt ID= (more detail) 80 17535438 Homo sapiens

I2D IEI012952 Protein protein interactors of human gene SRA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRA1 (SwissProt ID=Q (more detail) 41 17535438 Homo sapiens

I2D WIG001985 DNA Replication DNA Replication (more detail) 41 NA Homo sapiens

WikiPathway WAG001005 Proteasome The proteasome is a protein-destroying apparatus involved in many essential cellular functions, such (more detail) 41 NA Homo sapiens

KEGG IEI012982 Protein protein interactors of human gene SRPK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRPK3 (SwissProt ID= (more detail) 62 17535438 Homo sapiens

I2D WEX000007 Autophagy The genes related to autophagy (cell function) in tumor using next-generation sequencer (NGS) readou (more detail) 62 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas TAX000457 Genes annotated by the GO term GO:0018193. The alteration of an amino acid residue in a peptide. (more detail) 62 NA Homo sapiens

MSigDB TAX030040 GO:0072529 biological process pyrimidine containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, (more detail) 34 NA Homo sapiens

GOA MEX001554 Genes associated with Kinase Inhibitor TAK 715 Genes associated with Kinase Inhibitor TAK-715, curated by the Drug Signature Database (DSigDB). (more detail) 34 25990557 Homo sapiens

DSigDB IEI002856 Protein protein interactors of human gene COPS7B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COPS7B (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D TAX000791 Genes annotated by the GO term GO:0006352. Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter. (more detail) 34 NA Homo sapiens

MSigDB TAX023783 GO:0042339 biological process keratan sulfate metabolic process The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units (more detail) 34 NA Homo sapiens

GOA TAX021300 GO:0032040 cellular component small subunit processome A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a (more detail) 34 NA Homo sapiens

GOA IEI002852 Protein protein interactors of human gene COPS4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COPS4 (SwissProt ID= (more detail) 82 17535438 Homo sapiens

I2D TAX026065 GO:0048145 biological process regulation of fibroblast proliferation Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibrob (more detail) 82 NA Homo sapiens

GOA IEI010255 Protein protein interactors of human gene POP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POP1 (SwissProt ID=Q (more detail) 52 17535438 Homo sapiens

I2D IEI012225 Protein protein interactors of human gene SIN3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIN3B (SwissProt ID= (more detail) 52 17535438 Homo sapiens

I2D IEI008309 Protein protein interactors of human gene MTA3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTA3 (SwissProt ID=Q (more detail) 52 17535438 Homo sapiens

I2D TAX032501 GO:1902402 biological process signal transduction involved in mitotic DNA damage checkpoint Any intracellular signal transduction that is involved in mitotic DNA damage checkpoint. (more detail) 57 NA Homo sapiens

GOA TAX030004 GO:0072413 biological process signal transduction involved in mitotic cell cycle checkpoint A signal transduction process that contributes to a mitotic cell cycle checkpoint. (more detail) 57 NA Homo sapiens

GOA IEI007864 Protein protein interactors of human gene MED8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED8 (SwissProt ID=Q (more detail) 57 17535438 Homo sapiens

I2D IEI005582 Protein protein interactors of human gene GTF2H1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2H1 (SwissProt ID (more detail) 57 17535438 Homo sapiens

I2D TAX032502 GO:1902403 biological process signal transduction involved in mitotic DNA integrity checkpoint Any intracellular signal transduction that is involved in mitotic DNA integrity checkpoint. (more detail) 57 NA Homo sapiens

GOA TAX032500 GO:1902400 biological process intracellular signal transduction involved in G1 DNA damage checkpoint Any intracellular signal transduction that is involved in G1 DNA damage checkpoint. (more detail) 57 NA Homo sapiens

GOA TAX030011 GO:0072431 biological process signal transduction involved in mitotic G1 DNA damage checkpoint A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage ch (more detail) 57 NA Homo sapiens

GOA IEI004936 Protein protein interactors of human gene FTSJ3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FTSJ3 (SwissProt ID= (more detail) 71 17535438 Homo sapiens

I2D IEI006451 Protein protein interactors of human gene IPO5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IPO5 (SwissProt ID=O (more detail) 84 17535438 Homo sapiens

I2D MAX001406 Genes down regulated in MEWO cells (melanoma) after 48h of methionine [PubChem=876] deprivation. Methionine deprivation stress (MDS) eliminates mitotic activity in melanoma cells regardless of stag (more detail) 64 NA Homo sapiens

MSigDB IEI002182 Protein protein interactors of human gene CDC34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC34 (SwissProt ID= (more detail) 64 17535438 Homo sapiens

I2D TAX025666 GO:0046620 biological process regulation of organ growth Any process that modulates the frequency, rate or extent of growth of an organ of an organism. (more detail) 88 NA Homo sapiens

GOA IEI007924 Protein protein interactors of human gene MEX3C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEX3C (SwissProt ID= (more detail) 88 17535438 Homo sapiens

I2D IEI013355 Protein protein interactors of human gene TAF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF7 (SwissProt ID=Q (more detail) 49 17535438 Homo sapiens

I2D IEI004880 Protein protein interactors of human gene FOXO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXO1 (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D WAG001612 Acute myeloid leukemia Acute myeloid leukemia (AML) is a disease that is characterized by uncontrolled proliferation of clo (more detail) 49 NA Homo sapiens

KEGG MAX001408 Genes down regulated in MEWO cells (melanoma) after 96 h of methionine [PubChem=876] deprivation. Methionine deprivation stress (MDS) eliminates mitotic activity in melanoma cells regardless of stag (more detail) 75 NA Homo sapiens

MSigDB IEI005653 Protein protein interactors of human gene H2AC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AC4 (SwissProt ID= (more detail) 94 17535438 Homo sapiens

I2D IEI011324 Protein protein interactors of human gene RING1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RING1 (SwissProt ID= (more detail) 59 17535438 Homo sapiens

I2D TAX014769 GO:0003707 molecular function steroid hormone receptor activity Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in (more detail) 59 NA Homo sapiens

GOA IEI002937 Protein protein interactors of human gene CPSF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CPSF1 (SwissProt ID= (more detail) 59 17535438 Homo sapiens

I2D IEI010647 Protein protein interactors of human gene PSMD10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD10 (SwissProt ID (more detail) 66 17535438 Homo sapiens

I2D IEI000655 Protein protein interactors of human gene ANXA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANXA1 (SwissProt ID= (more detail) 100 17535438 Homo sapiens

I2D FEX001908 Lung Joo07 54genes Table 1. A partial list of genes induced and repressed in H460 cells after FOH treatment (more detail) 54 17699800 Homo sapiens

GeneSigDB MAX002846 Genes up regulated in Caco 2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 6h. Shigella invades the human intestinal mucosa, thus causing bacillary dysentery, an acute recto-colit (more detail) 54 NA Homo sapiens

MSigDB TAX017898 GO:0010332 biological process response to gamma radiation Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 54 NA Homo sapiens

GOA IEI012582 Protein protein interactors of human gene SMAD6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMAD6 (SwissProt ID= (more detail) 54 17535438 Homo sapiens

I2D WIG001504 FGF Pathway FGF Pathway (more detail) 77 NA Homo sapiens

Protein Lounge IEI003538 Protein protein interactors of human gene DHX30 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHX30 (SwissProt ID= (more detail) 77 17535438 Homo sapiens

I2D TAX015861 GO:0005669 cellular component transcription factor TFIID complex A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass i (more detail) 37 NA Homo sapiens

GOA IEI003414 Protein protein interactors of human gene DDX23 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX23 (SwissProt ID= (more detail) 37 17535438 Homo sapiens

I2D TAX032557 GO:1902562 cellular component H4 histone acetyltransferase complex A protein complex which is capable of H4 histone acetyltransferase activity. (more detail) 37 NA Homo sapiens

GOA TAX000775 Genes annotated by the GO term GO:0006790. The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. (more detail) 37 NA Homo sapiens

MSigDB WIG000574 N Glycan biosynthesis N-glycans or asparagine-linked glycans are major constituents of glycoproteins in eukaryotes. N-glyc (more detail) 46 NA Homo sapiens

MSigDB MEX000858 Genes associated with Approved Drug retinoic acid Genes associated with Approved Drug retinoic acid, curated by the Drug Signature Database (DSigDB). (more detail) 46 25990557 Homo sapiens

DSigDB IEI005805 Protein protein interactors of human gene HES1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HES1 (SwissProt ID=Q (more detail) 46 17535438 Homo sapiens

I2D IEI002938 Protein protein interactors of human gene CPSF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CPSF2 (SwissProt ID= (more detail) 46 17535438 Homo sapiens

I2D IEI002043 Protein protein interactors of human gene CCNE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNE1 (SwissProt ID= (more detail) 79 17535438 Homo sapiens

I2D FEX001755 Liver Sakai08 86genes Table 3. Biological processes for genes up-regulated in PBMCs of HCC patients (more detail) 79 19074895 Homo sapiens

GeneSigDB IEI013004 Protein protein interactors of human gene SRSF9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF9 (SwissProt ID= (more detail) 68 17535438 Homo sapiens

I2D TAX019841 GO:0019843 molecular function rRNA binding Interacting selectively and non-covalently with ribosomal RNA. (more detail) 61 NA Homo sapiens

GOA MOX004224 Genes associated with Computational Drug Signature clioquinol Genes associated with Computational Drug Signature clioquinol, curated by the Drug Signature Databas (more detail) 81 25990557 Homo sapiens

DSigDB IEI015242 Protein protein interactors of human gene ZC3H13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZC3H13 (SwissProt ID (more detail) 43 17535438 Homo sapiens

I2D IEI000553 Protein protein interactors of human gene ANAPC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC1 (SwissProt ID (more detail) 43 17535438 Homo sapiens

I2D IEI010220 Protein protein interactors of human gene POLR2D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2D (SwissProt ID (more detail) 43 17535438 Homo sapiens

I2D FOX000456 Genes in the cancer module 125 (more detail) 43 NA Homo sapiens

MSigDB IEI007859 Protein protein interactors of human gene MED30 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED30 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D IEI009978 Protein protein interactors of human gene PJA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PJA1 (SwissProt ID=Q (more detail) 40 17535438 Homo sapiens

I2D WAG001458 il 2 receptor beta chain in t cell activation The IL-2 receptor is a key component of immune sigling and is required for the activation, prolifera (more detail) 40 NA Homo sapiens

BioCarta TAX013279 GO:0000152 cellular component nuclear ubiquitin ligase complex A ubiquitin ligase complex found in the nucleus. (more detail) 40 NA Homo sapiens

GOA WAG000825 keratinocyte differentiation The epidermis, which provides a protective barrier that undergoes a constant renewal, is a multi-lay (more detail) 40 NA Homo sapiens

BioCarta WAG001624 Sphingolipid metabolism (more detail) 40 NA Homo sapiens

KEGG IEI010212 Protein protein interactors of human gene POLR1C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR1C (SwissProt ID (more detail) 83 17535438 Homo sapiens

I2D IEI012744 Protein protein interactors of human gene SOCS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOCS1 (SwissProt ID= (more detail) 70 17535438 Homo sapiens

I2D MOX002944 Genes associated with Computational Drug Signature 170449 18 0 Genes associated with Computational Drug Signature 170449-18-0, curated by the Drug Signature Databa (more detail) 70 25990557 Homo sapiens

DSigDB IEI007844 Protein protein interactors of human gene MED15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED15 (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D IEI008780 Protein protein interactors of human gene NFATC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFATC1 (SwissProt ID (more detail) 51 17535438 Homo sapiens

I2D MAX000484 Protein biosynthesis, transport or catabolism genes up regulated in hyperploid multiple myeloma (MM) compared to the non hyperploid MM samples. Hyperdiploid multiple myeloma (H-MM) is the most common form of myeloma. In this gene expression pro (more detail) 51 NA Homo sapiens

MSigDB WIG001967 IL 4 signaling pathway IL-4 signaling pathway (more detail) 51 NA Homo sapiens

WikiPathway TAX016710 GO:0006977 biological process DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent prot (more detail) 56 NA Homo sapiens

GOA MEX000657 Genes associated with Approved Drug rubidomycin hydrochloride Genes associated with Approved Drug rubidomycin hydrochloride, curated by the Drug Signature Databas (more detail) 85 25990557 Homo sapiens

DSigDB IEI005056 Protein protein interactors of human gene GANAB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GANAB (SwissProt ID= (more detail) 85 17535438 Homo sapiens

I2D TAX017134 GO:0008214 biological process protein dealkylation The removal of an alkyl group from a protein amino acid. An alkyl group is any group derived from an (more detail) 33 NA Homo sapiens

GOA TAX019048 GO:0016486 biological process peptide hormone processing The generation of a mature peptide hormone by posttranslational processing of a prohormone. (more detail) 33 NA Homo sapiens

GOA TAX017561 GO:0009164 biological process nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any one of a family of organic mol (more detail) 33 NA Homo sapiens

GOA FAX003055 GSEA KEGG Lung Cancer Tissue Explants (Extracellular Vesicles) Spliceosome Top 3 pathways enriched in lung cancer tissue extract extracellular vesicle particles compared to ma (more detail) 33 32795414 Homo sapiens

Cell TAX024536 GO:0043928 biological process exonucleolytic nuclear transcribed mRNA catabolic process involved in deadenylation dependent decay The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-t (more detail) 33 NA Homo sapiens

GOA TAX025467 GO:0046131 biological process pyrimidine ribonucleoside metabolic process The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine b (more detail) 33 NA Homo sapiens

GOA TAX017639 GO:0009262 biological process deoxyribonucleotide metabolic process The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyr (more detail) 33 NA Homo sapiens

GOA TAX023698 GO:0042157 biological process lipoprotein metabolic process The chemical reactions and pathways involving any conjugated, water-soluble protein in which the cov (more detail) 33 NA Homo sapiens

GOA TAX023310 GO:0036260 biological process RNA capping The sequence of enzymatic reactions by which a cap structure is added to the 5' end of a nascent RNA (more detail) 33 NA Homo sapiens

GOA TAX017706 GO:0009452 biological process 7 methylguanosine RNA capping The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine lin (more detail) 33 NA Homo sapiens

GOA TAX024125 GO:0043038 biological process amino acid activation The modification of an amino acid to an active form, for incorporation into a peptide, protein or ot (more detail) 33 NA Homo sapiens

GOA WAG000620 DNA replication A complex network of interacting proteins and enzymes is required for D replication. Generally, D re (more detail) 33 NA Homo sapiens

KEGG WIG000997 Genes involved in mRNA 3' end processing (more detail) 33 NA Homo sapiens

MSigDB TAX016285 GO:0006369 biological process termination of RNA polymerase II transcription The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is c (more detail) 33 NA Homo sapiens

GOA TAX016364 GO:0006482 biological process protein demethylation The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by (more detail) 33 NA Homo sapiens

GOA TAX001379 Genes annotated by the GO term GO:0003697. Interacting selectively with single stranded DNA. (more detail) 33 NA Homo sapiens

MSigDB TAX001352 Genes annotated by the GO term GO:0004702. (more detail) 33 NA Homo sapiens

MSigDB MEX002418 Genes associated with Kinase Inhibitor Regorafenib Genes associated with Kinase Inhibitor Regorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 33 25990557 Homo sapiens

DSigDB WAG000671 Cleavage of Growing Transcript in the Termination Region (more detail) 33 NA Homo sapiens

Reactome WIG001266 Genes involved in Telomere Maintenance (more detail) 33 NA Homo sapiens

MSigDB MEX002298 Genes associated with Kinase Inhibitor IPA 3 Genes associated with Kinase Inhibitor IPA-3, curated by the Drug Signature Database (DSigDB). (more detail) 33 25990557 Homo sapiens

DSigDB MOX003683 Genes associated with Computational Drug Signature GNF Pf 4325 Genes associated with Computational Drug Signature GNF-Pf-4325, curated by the Drug Signature Databa (more detail) 87 25990557 Homo sapiens

DSigDB IEI007824 Protein protein interactors of human gene MDM4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MDM4 (SwissProt ID=O (more detail) 63 17535438 Homo sapiens

I2D TAX029493 GO:0071479 biological process cellular response to ionizing radiation Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 63 NA Homo sapiens

GOA IEI003909 Protein protein interactors of human gene EBNA1BP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EBNA1BP2 (SwissProt (more detail) 63 17535438 Homo sapiens

I2D TAX026863 GO:0051193 biological process regulation of cofactor metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 72 NA Homo sapiens

GOA MOX002824 Genes associated with Computational Drug Signature SB 202190 Genes associated with Computational Drug Signature SB 202190, curated by the Drug Signature Database (more detail) 91 25990557 Homo sapiens

DSigDB IEI003648 Protein protein interactors of human gene DNAJA3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJA3 (SwissProt ID (more detail) 95 17535438 Homo sapiens

I2D TAX023963 GO:0042692 biological process muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. (more detail) 74 NA Homo sapiens

GOA IEI011128 Protein protein interactors of human gene RCC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RCC1 (SwissProt ID=P (more detail) 99 17535438 Homo sapiens

I2D IEI010618 Protein protein interactors of human gene PSIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSIP1 (SwissProt ID= (more detail) 48 17535438 Homo sapiens

I2D WIG000077 Notch mediated HES/HEY network (more detail) 48 NA Homo sapiens

MSigDB TAX013496 GO:0000792 cellular component heterochromatin A compact and highly condensed form of chromatin. (more detail) 65 NA Homo sapiens

GOA MEX000882 Genes associated with Approved Drug nilotinib Genes associated with Approved Drug nilotinib, curated by the Drug Signature Database (DSigDB). (more detail) 65 25990557 Homo sapiens

DSigDB WIG001598 14 3 3 Induced Apoptosis 14-3-3 Induced Apoptosis (more detail) 65 NA Homo sapiens

Protein Lounge TAX034789 GO:2000573 biological process positive regulation of DNA biosynthetic process Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process. (more detail) 65 NA Homo sapiens

GOA MOX005139 Genes associated with Computational Drug Signature alpha Tocopherol Genes associated with Computational Drug Signature alpha-Tocopherol, curated by the Drug Signature D (more detail) 58 25990557 Homo sapiens

DSigDB WIG000408 Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) The most recognized mechanism by which peroxisome proliferators regulated gene expresssion is throug (more detail) 58 NA Homo sapiens

MSigDB IEI001070 Protein protein interactors of human gene ATP2A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP2A2 (SwissProt ID (more detail) 76 17535438 Homo sapiens

I2D IEI001492 Protein protein interactors of human gene BUB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BUB3 (SwissProt ID=O (more detail) 76 17535438 Homo sapiens

I2D WIG000139 p73 transcription factor network (more detail) 76 NA Homo sapiens

MSigDB WIG001311 Genes involved in Unfolded Protein Response (more detail) 76 NA Homo sapiens

MSigDB IEI002558 Protein protein interactors of human gene CIITA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CIITA (SwissProt ID= (more detail) 53 17535438 Homo sapiens

I2D IEI006490 Protein protein interactors of human gene IRF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IRF7 (SwissProt ID=Q (more detail) 78 17535438 Homo sapiens

I2D IEI014594 Protein protein interactors of human gene UBE2U from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2U (SwissProt ID= (more detail) 67 17535438 Homo sapiens

I2D TAX019201 GO:0016765 molecular function transferase activity, transferring alkyl or aryl (other than methyl) groups Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to an (more detail) 67 NA Homo sapiens

GOA TAX034893 GO:2000736 biological process regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of stem cell differentiation. (more detail) 67 NA Homo sapiens

GOA FOX000198 Neighborhood of RBBP6 Neighborhood of RBBP6 retinoblastoma binding protein 6 in the GNF2 expression compendium (more detail) 67 NA Homo sapiens

MSigDB IEI012746 Protein protein interactors of human gene SOCS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOCS3 (SwissProt ID= (more detail) 80 17535438 Homo sapiens

I2D IEI008182 Protein protein interactors of human gene MRPL12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPL12 (SwissProt ID (more detail) 80 17535438 Homo sapiens

I2D MAX002500 Selected genes up regulated in peripheral blood monocytes (PBMC) of patients with hepatocellular carcinoma (HCC) compared to those with chronic hepatitis. Hepatocellular carcinoma (HCC) is frequently associated with infiltrating mononuclear inflammatory c (more detail) 80 NA Homo sapiens

MSigDB WAG000398 T cell receptor signaling pathway Activation of T lymphocytes is a key event for an efficient response of the immune system. It requir (more detail) 80 NA Homo sapiens

KEGG TAX020547 GO:0030521 biological process androgen receptor signaling pathway Any series of molecular signals generated as a consequence of an androgen binding to its receptor. (more detail) 45 NA Homo sapiens

GOA MEX001422 Genes associated with Kinase Inhibitor 929095 18 1 Genes associated with Kinase Inhibitor 929095-18-1, curated by the Drug Signature Database (DSigDB). (more detail) 45 25990557 Homo sapiens

DSigDB IEI001826 Protein protein interactors of human gene CASP9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASP9 (SwissProt ID= (more detail) 60 17535438 Homo sapiens

I2D IEI006899 Protein protein interactors of human gene KLF5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF5 (SwissProt ID=Q (more detail) 36 17535438 Homo sapiens

I2D TAX023701 GO:0042162 molecular function telomeric DNA binding Interacting selectively and non-covalently with a telomere, a specific structure at the end of a lin (more detail) 36 NA Homo sapiens

GOA WIG001307 Genes involved in Triglyceride Biosynthesis (more detail) 36 NA Homo sapiens

MSigDB WIG000845 Genes involved in Formation of RNA Pol II elongation complex (more detail) 36 NA Homo sapiens

MSigDB IEI001146 Protein protein interactors of human gene ATXN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATXN3 (SwissProt ID= (more detail) 69 17535438 Homo sapiens

I2D FOX000180 Neighborhood of NPM1 Neighborhood of NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) in the GNF2 expression (more detail) 69 NA Homo sapiens

MSigDB WIG001205 Genes involved in Signaling by FGFR mutants (more detail) 42 NA Homo sapiens

MSigDB WIG001645 RANK Signaling in Osteoclasts RANK Signaling in Osteoclasts (more detail) 42 NA Homo sapiens

Protein Lounge MOX014804 Genes associated with Computational Drug Signature Retinoic acid Genes associated with Computational Drug Signature Retinoic acid, curated by the Drug Signature Data (more detail) 42 25990557 Homo sapiens

DSigDB FOX000489 Genes in the cancer module 158 (more detail) 42 NA Homo sapiens

MSigDB IEI008079 Protein protein interactors of human gene MNAT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MNAT1 (SwissProt ID= (more detail) 55 17535438 Homo sapiens

I2D TAX024726 GO:0044390 molecular function ubiquitin like protein conjugating enzyme binding Interacting selectively and non-covalently with a ubiquitin-like protein conjugating enzyme such as (more detail) 39 NA Homo sapiens

GOA WIG000232 JNK MAPK Pathway na (more detail) 39 NA Homo sapiens

MSigDB WIG000523 Glutathione metabolism (more detail) 50 NA Homo sapiens

MSigDB MOX000028 Genes associated with Computational Drug Signature geldanamycin Genes associated with Computational Drug Signature geldanamycin, curated by the Drug Signature Datab (more detail) 50 25990557 Homo sapiens

DSigDB TAX027456 GO:0052813 molecular function phosphatidylinositol bisphosphate kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol bisphosphate = ADP + a phosphatidylinositol (more detail) 71 NA Homo sapiens

GOA TAX016971 GO:0007569 biological process cell aging An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may oc (more detail) 62 NA Homo sapiens

GOA MOX006417 Genes associated with Computational Drug Signature 9,10 Phenanthrenequinone Genes associated with Computational Drug Signature 9,10-Phenanthrenequinone, curated by the Drug Sig (more detail) 90 25990557 Homo sapiens

DSigDB TAX031271 GO:0099024 biological process plasma membrane invagination An infolding of the plasma membrane. (more detail) 94 NA Homo sapiens

GOA MOX005048 Genes associated with Computational Drug Signature okadaic acid Genes associated with Computational Drug Signature okadaic acid, curated by the Drug Signature Datab (more detail) 96 25990557 Homo sapiens

DSigDB TAX020524 GO:0030488 biological process tRNA methylation The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. (more detail) 32 NA Homo sapiens

GOA TAX020343 GO:0030166 biological process proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in (more detail) 32 NA Homo sapiens

GOA TAX025409 GO:0046039 biological process GTP metabolic process The chemical reactions and pathways involving GTP, guanosine triphosphate. (more detail) 32 NA Homo sapiens

GOA TAX024198 GO:0043171 biological process peptide catabolic process The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more ( (more detail) 32 NA Homo sapiens

GOA TAX017638 GO:0009261 biological process ribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consi (more detail) 32 NA Homo sapiens

GOA TAX019292 GO:0016896 molecular function exoribonuclease activity, producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residu (more detail) 32 NA Homo sapiens

GOA TAX024126 GO:0043039 biological process tRNA aminoacylation The chemical reactions and pathways by which the various amino acids become bonded to their correspo (more detail) 32 NA Homo sapiens

GOA MEX002328 Genes associated with Kinase Inhibitor SureCN571763 Genes associated with Kinase Inhibitor SureCN571763, curated by the Drug Signature Database (DSigDB) (more detail) 32 25990557 Homo sapiens

DSigDB FOX000600 Genes in the cancer module 28 (more detail) 32 NA Homo sapiens

MSigDB FOX000598 Genes in the cancer module 278 (more detail) 32 NA Homo sapiens

MSigDB MEX001438 Genes associated with Kinase Inhibitor Ro 3306 Genes associated with Kinase Inhibitor Ro-3306, curated by the Drug Signature Database (DSigDB). (more detail) 32 25990557 Homo sapiens

DSigDB TAX016286 GO:0006370 biological process 7 methylguanosine mRNA capping Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript. (more detail) 32 NA Homo sapiens

GOA TAX001167 Genes annotated by the GO term GO:0016251. Any function that supports basal (unregulated) transcription of genes by core RNA polymerase II. Five general transcription factors are necessary and sufficient for such basal transcription in yeast: TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA binding protein (TBF). (more detail) 32 NA Homo sapiens

MSigDB IEI005146 Protein protein interactors of human gene GEMIN4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GEMIN4 (SwissProt ID (more detail) 73 17535438 Homo sapiens

I2D TAX035008 GO:2001021 biological process negative regulation of response to DNA damage stimulus Any process that stops, prevents or reduces the frequency, rate or extent of response to DNA damage (more detail) 75 NA Homo sapiens

GOA TAX025190 GO:0045638 biological process negative regulation of myeloid cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell different (more detail) 75 NA Homo sapiens

GOA WIG000643 VEGF signaling pathway There is now much evidence that VEGFR-2 is the major mediator of VEGF-driven responses in endothelia (more detail) 75 NA Homo sapiens

MSigDB IEI012999 Protein protein interactors of human gene SRSF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF4 (SwissProt ID= (more detail) 57 17535438 Homo sapiens

I2D IEI013001 Protein protein interactors of human gene SRSF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF6 (SwissProt ID= (more detail) 57 17535438 Homo sapiens

I2D WIG000017 ATF 2 transcription factor network (more detail) 57 NA Homo sapiens

MSigDB MOX014711 Genes associated with Computational Drug Signature quercetin Genes associated with Computational Drug Signature quercetin, curated by the Drug Signature Database (more detail) 57 25990557 Homo sapiens

DSigDB IEI010933 Protein protein interactors of human gene RAD18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD18 (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D TAX021070 GO:0031593 molecular function polyubiquitin modification dependent protein binding Interacting selectively and non-covalently with a protein upon poly-ubiquitination of the target pro (more detail) 47 NA Homo sapiens

GOA TAX033851 GO:1905268 biological process negative regulation of chromatin organization Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization. (more detail) 47 NA Homo sapiens

GOA TAX034866 GO:2000677 biological process regulation of transcription regulatory region DNA binding Any process that modulates the frequency, rate or extent of transcription regulatory region DNA bind (more detail) 47 NA Homo sapiens

GOA WIG000775 Genes involved in Cross presentation of soluble exogenous antigens (endosomes) (more detail) 47 NA Homo sapiens

MSigDB IEI000559 Protein protein interactors of human gene ANAPC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC2 (SwissProt ID (more detail) 47 17535438 Homo sapiens

I2D IEI014583 Protein protein interactors of human gene UBE2L6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2L6 (SwissProt ID (more detail) 47 17535438 Homo sapiens

I2D TAX034093 GO:1905897 biological process regulation of response to endoplasmic reticulum stress Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress (more detail) 77 NA Homo sapiens

GOA IEI001874 Protein protein interactors of human gene CBX4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CBX4 (SwissProt ID=O (more detail) 77 17535438 Homo sapiens

I2D TAX016607 GO:0006810 biological process transport The directed movement of substances (such as macromolecules, small molecules, ions) or cellular comp (more detail) 4023 NA Homo sapiens

GOA IEI004567 Protein protein interactors of human gene FANCD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FANCD2 (SwissProt ID (more detail) 52 17535438 Homo sapiens

I2D IEI002173 Protein protein interactors of human gene CDC16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC16 (SwissProt ID= (more detail) 52 17535438 Homo sapiens

I2D IEI005581 Protein protein interactors of human gene GTF2F2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2F2 (SwissProt ID (more detail) 66 17535438 Homo sapiens

I2D IEI008473 Protein protein interactors of human gene MYO1C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYO1C (SwissProt ID= (more detail) 59 17535438 Homo sapiens

I2D FOX000396 Neighborhood of RPA1 Neighborhood of RPA1 replication protein A1, 70kDa in the MORF expression compendium (more detail) 59 NA Homo sapiens

MSigDB IEI001801 Protein protein interactors of human gene CARM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CARM1 (SwissProt ID= (more detail) 83 17535438 Homo sapiens

I2D FOX000702 Genes in the cancer module 403 (more detail) 44 NA Homo sapiens

MSigDB TAX021034 GO:0031519 cellular component PcG protein complex A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polyc (more detail) 44 NA Homo sapiens

GOA IEI002197 Protein protein interactors of human gene CDC45 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC45 (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D IEI014256 Protein protein interactors of human gene TRIM5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM5 (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D WIG000009 AP 1 transcription factor network (more detail) 68 NA Homo sapiens

MSigDB TAX000288 Genes annotated by the GO term GO:0051325. Progression through interphase, the stage of cell cycle between successive rounds of chromosome segregation. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs. (more detail) 68 NA Homo sapiens

MSigDB MOX004319 Genes associated with Computational Drug Signature metformin Genes associated with Computational Drug Signature metformin, curated by the Drug Signature Database (more detail) 85 25990557 Homo sapiens

DSigDB TAX031948 GO:1900542 biological process regulation of purine nucleotide metabolic process Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process. (more detail) 85 NA Homo sapiens

GOA IEI013093 Protein protein interactors of human gene STAT5B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAT5B (SwissProt ID (more detail) 85 17535438 Homo sapiens

I2D MEX002063 Genes associated with Kinase Inhibitor Erlotinib Genes associated with Kinase Inhibitor Erlotinib, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens

DSigDB WAG000624 Glycine, serine and threonine metabolism Serine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis [MD: (more detail) 35 NA Homo sapiens

KEGG TAX023197 GO:0036002 molecular function pre mRNA binding Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecu (more detail) 35 NA Homo sapiens

GOA TAX021384 GO:0032205 biological process negative regulation of telomere maintenance Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects (more detail) 35 NA Homo sapiens

GOA MEX002398 Genes associated with Kinase Inhibitor Erlotinib Genes associated with Kinase Inhibitor Erlotinib, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens

DSigDB WIG001438 Cell Cycle Control of Chromosomal Replication Cell Cycle Control of Chromosomal Replication (more detail) 35 NA Homo sapiens

Protein Lounge IEI013695 Protein protein interactors of human gene TIAL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TIAL1 (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D IEI007281 Protein protein interactors of human gene LIN28A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LIN28A (SwissProt ID (more detail) 87 17535438 Homo sapiens

I2D IEI010448 Protein protein interactors of human gene PRDX6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRDX6 (SwissProt ID= (more detail) 87 17535438 Homo sapiens

I2D FEX001031 Esophagus Barrett03 104genes Table 1 Biological Function of Genes in TP53?/? Tetraploid Cluster (more detail) 91 12874028 Homo sapiens

GeneSigDB TAX017360 GO:0008593 biological process regulation of Notch signaling pathway Any process that modulates the frequency, rate or extent of the Notch signaling pathway. (more detail) 91 NA Homo sapiens

GOA IEI002784 Protein protein interactors of human gene COIL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COIL (SwissProt ID=P (more detail) 93 17535438 Homo sapiens

I2D TAX021894 GO:0032963 biological process collagen metabolic process The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very h (more detail) 54 NA Homo sapiens

GOA IEI002842 Protein protein interactors of human gene COP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COP1 (SwissProt ID=Q (more detail) 70 17535438 Homo sapiens

I2D MOX005061 Genes associated with Computational Drug Signature ritonavir Genes associated with Computational Drug Signature ritonavir, curated by the Drug Signature Database (more detail) 70 25990557 Homo sapiens

DSigDB IEI005902 Protein protein interactors of human gene HMGB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMGB2 (SwissProt ID= (more detail) 41 17535438 Homo sapiens

I2D IEI015083 Protein protein interactors of human gene WRN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WRN (SwissProt ID=Q1 (more detail) 41 17535438 Homo sapiens

I2D IEI007152 Protein protein interactors of human gene LARP7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LARP7 (SwissProt ID= (more detail) 41 17535438 Homo sapiens

I2D TAX001446 Genes annotated by the GO term GO:0008194. Catalysis of the transfer of a glycosyl group from a UDP sugar to a small hydrophobic molecule. (more detail) 41 NA Homo sapiens

MSigDB MOX000194 Genes associated with Computational Drug Signature Myristicin Genes associated with Computational Drug Signature Myristicin, curated by the Drug Signature Databas (more detail) 41 25990557 Homo sapiens

DSigDB TAX027299 GO:0051972 biological process regulation of telomerase activity Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of th (more detail) 49 NA Homo sapiens

GOA TAX021586 GO:0032481 biological process positive regulation of type I interferon production Any process that activates or increases the frequency, rate, or extent of type I interferon producti (more detail) 61 NA Homo sapiens

GOA IEI011639 Protein protein interactors of human gene RRP12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRP12 (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D TAX024201 GO:0043175 molecular function RNA polymerase core enzyme binding Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific (more detail) 38 NA Homo sapiens

GOA IEI003409 Protein protein interactors of human gene DDX18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX18 (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D TAX013618 GO:0001102 molecular function RNA polymerase II activating transcription factor binding Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor (more detail) 38 NA Homo sapiens

GOA WIG000353 IL 2 Receptor Beta Chain in T cell Activation The IL-2 receptor is a key component of immune signaling and is required for the activation, prolife (more detail) 38 NA Homo sapiens

MSigDB TAX031932 GO:1900407 biological process regulation of cellular response to oxidative stress Any process that modulates the frequency, rate or extent of cellular response to oxidative stress. (more detail) 72 NA Homo sapiens

GOA IEI012994 Protein protein interactors of human gene SRSF10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRSF10 (SwissProt ID (more detail) 74 17535438 Homo sapiens

I2D WEX000035 Glycan Sensing The genes related to glycan sensing (innate immunity) in tumor using next-generation sequencer (NGS) (more detail) 63 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas MOX003210 Genes associated with Computational Drug Signature T0901317 Genes associated with Computational Drug Signature T0901317, curated by the Drug Signature Database (more detail) 63 25990557 Homo sapiens

DSigDB TAX019778 GO:0019692 biological process deoxyribose phosphate metabolic process The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deox (more detail) 31 NA Homo sapiens

GOA IEI015229 Protein protein interactors of human gene ZBTB7A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB7A (SwissProt ID (more detail) 31 17535438 Homo sapiens

I2D TAX017552 GO:0009154 biological process purine ribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compoun (more detail) 31 NA Homo sapiens

GOA TAX017616 GO:0009225 biological process nucleotide sugar metabolic process The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrat (more detail) 31 NA Homo sapiens

GOA TAX024487 GO:0043631 biological process RNA polyadenylation The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule. (more detail) 31 NA Homo sapiens

GOA TAX019103 GO:0016577 biological process histone demethylation The modification of histones by removal of methyl groups. (more detail) 31 NA Homo sapiens

GOA TAX021624 GO:0032543 biological process mitochondrial translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This (more detail) 31 NA Homo sapiens

GOA WAG001302 Formation of the HIV 1 Early Elongation Complex (more detail) 31 NA Homo sapiens

Reactome WAG001216 Base excision repair Base excision repair (BER) is the predomint D damage repair pathway for the processing of small base (more detail) 31 NA Homo sapiens

KEGG MEX002019 Genes associated with Kinase Inhibitor Canertinib Genes associated with Kinase Inhibitor Canertinib, curated by the Drug Signature Database (DSigDB). (more detail) 31 25990557 Homo sapiens

DSigDB MEX001223 Genes associated with Kinase Inhibitor NVP TAE684 Genes associated with Kinase Inhibitor NVP-TAE684, curated by the Drug Signature Database (DSigDB). (more detail) 31 25990557 Homo sapiens

DSigDB WAG000058 Activation of ATR in response to replication stress (more detail) 31 NA Homo sapiens

Reactome WAG001111 HIV 1 Transcription Elongation (more detail) 31 NA Homo sapiens

Reactome WAG001499 Formation of the Early Elongation Complex (more detail) 31 NA Homo sapiens

Reactome TAX016225 GO:0006278 biological process RNA dependent DNA biosynthetic process A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. rever (more detail) 31 NA Homo sapiens

GOA TAX016219 GO:0006270 biological process DNA replication initiation The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent lo (more detail) 31 NA Homo sapiens

GOA TAX016502 GO:0006656 biological process phosphatidylcholine biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a cla (more detail) 31 NA Homo sapiens

GOA WIG001115 Genes involved in Purine metabolism (more detail) 31 NA Homo sapiens

MSigDB WIG000526 Glycine, serine and threonine metabolism Serine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis , and glycine is derived (more detail) 31 NA Homo sapiens

MSigDB WIG001459 Crosstalk Between CARM1 and ESRs Crosstalk Between CARM1 and ESRs (more detail) 56 NA Homo sapiens

Protein Lounge IEI011204 Protein protein interactors of human gene RFC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RFC5 (SwissProt ID=P (more detail) 56 17535438 Homo sapiens

I2D TAX026866 GO:0051196 biological process regulation of coenzyme metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 56 NA Homo sapiens

GOA IEI008743 Protein protein interactors of human gene NELFB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NELFB (SwissProt ID= (more detail) 56 17535438 Homo sapiens

I2D TAX017657 GO:0009311 biological process oligosaccharide metabolic process The chemical reactions and pathways involving oligosaccharides, molecules with between two and (abou (more detail) 56 NA Homo sapiens

GOA IEI002450 Protein protein interactors of human gene CHAF1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHAF1A (SwissProt ID (more detail) 76 17535438 Homo sapiens

I2D WEX000078 p53 Signaling The genes related to p53 signaling (signaling pathways) in tumor using next-generation sequencer (NG (more detail) 76 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI006427 Protein protein interactors of human gene INTS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS1 (SwissProt ID= (more detail) 46 17535438 Homo sapiens

I2D WIG000128 Calcineurin regulated NFAT dependent transcription in lymphocytes (more detail) 46 NA Homo sapiens

MSigDB MOX003146 Genes associated with Computational Drug Signature Erlotinib Genes associated with Computational Drug Signature Erlotinib, curated by the Drug Signature Database (more detail) 46 25990557 Homo sapiens

DSigDB WIG001585 NF kappaB Activation by Viruses NF-kappaB Activation by Viruses (more detail) 46 NA Homo sapiens

Protein Lounge WIG000600 Proteasome The proteasome is a protein-destroying apparatus involved in many essential cellular functions, such (more detail) 46 NA Homo sapiens

MSigDB FOX000133 Neighborhood of ELAC2 Neighborhood of ELAC2 elaC homolog 2 (E. coli) in the GNF2 expression compendium (more detail) 46 NA Homo sapiens

MSigDB IEI001330 Protein protein interactors of human gene BHLHE40 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BHLHE40 (SwissProt I (more detail) 78 17535438 Homo sapiens

I2D IEI006986 Protein protein interactors of human gene KPNA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KPNA1 (SwissProt ID= (more detail) 78 17535438 Homo sapiens

I2D IEI006069 Protein protein interactors of human gene HSPA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSPA2 (SwissProt ID= (more detail) 78 17535438 Homo sapiens

I2D WIG000878 Genes involved in Glycerophospholipid biosynthesis (more detail) 78 NA Homo sapiens

MSigDB TAX032887 GO:1903313 biological process positive regulation of mRNA metabolic process Any process that activates or increases the frequency, rate or extent of mRNA metabolic process. (more detail) 65 NA Homo sapiens

GOA IEI002177 Protein protein interactors of human gene CDC25A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC25A (SwissProt ID (more detail) 65 17535438 Homo sapiens

I2D TAX028966 GO:0070498 biological process interleukin 1 mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface (more detail) 51 NA Homo sapiens

GOA TAX024338 GO:0043392 biological process negative regulation of DNA binding Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any p (more detail) 51 NA Homo sapiens

GOA TAX001439 Genes annotated by the GO term GO:0019199. (more detail) 51 NA Homo sapiens

MSigDB WIG000986 Genes involved in Metabolism of vitamins and cofactors (more detail) 51 NA Homo sapiens

MSigDB MOX017400 Genes associated with Computational Drug Signature Vorinostat Genes associated with Computational Drug Signature Vorinostat, curated by the Drug Signature Databas (more detail) 82 25990557 Homo sapiens

DSigDB TAX033409 GO:1904356 biological process regulation of telomere maintenance via telomere lengthening Any process that modulates the frequency, rate or extent of telomere maintenance via telomere length (more detail) 58 NA Homo sapiens

GOA IEI002032 Protein protein interactors of human gene CCNA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNA1 (SwissProt ID= (more detail) 84 17535438 Homo sapiens

I2D IEI008432 Protein protein interactors of human gene MYH10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYH10 (SwissProt ID= (more detail) 84 17535438 Homo sapiens

I2D WEX000028 Estrogen Signaling The genes related to estrogen signaling (signaling pathways) in tumor using next-generation sequence (more detail) 84 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI000103 Protein protein interactors of human gene ACACA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACACA (SwissProt ID= (more detail) 67 17535438 Homo sapiens

I2D TAX032284 GO:1901863 biological process positive regulation of muscle tissue development Any process that activates or increases the frequency, rate or extent of muscle tissue development. (more detail) 67 NA Homo sapiens

GOA IEI002176 Protein protein interactors of human gene CDC23 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC23 (SwissProt ID= (more detail) 86 17535438 Homo sapiens

I2D MOX016245 Genes associated with Computational Drug Signature Heparitin Genes associated with Computational Drug Signature Heparitin, curated by the Drug Signature Database (more detail) 90 25990557 Homo sapiens

DSigDB TAX018262 GO:0010972 biological process negative regulation of G2/M transition of mitotic cell cycle Any cell cycle regulatory process that decreases the rate or extent of progression of a cell from G2 (more detail) 43 NA Homo sapiens

GOA TAX023690 GO:0042136 biological process neurotransmitter biosynthetic process The chemical reactions and pathways resulting in the formation of any of a group of substances that (more detail) 43 NA Homo sapiens

GOA MOX001315 Genes associated with Computational Drug Signature Andrographolide Genes associated with Computational Drug Signature Andrographolide, curated by the Drug Signature Da (more detail) 43 25990557 Homo sapiens

DSigDB WIG000788 Genes involved in Deadenylation dependent mRNA decay (more detail) 43 NA Homo sapiens

MSigDB MOX014799 Genes associated with Computational Drug Signature resveratrol Genes associated with Computational Drug Signature resveratrol, curated by the Drug Signature Databa (more detail) 43 25990557 Homo sapiens

DSigDB WIG001076 Genes involved in PI3K Cascade (more detail) 69 NA Homo sapiens

MSigDB TAX024336 GO:0043388 biological process positive regulation of DNA binding Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process (more detail) 53 NA Homo sapiens

GOA IEI003437 Protein protein interactors of human gene DDX56 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX56 (SwissProt ID= (more detail) 53 17535438 Homo sapiens

I2D TAX025541 GO:0046365 biological process monosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcoho (more detail) 60 NA Homo sapiens

GOA FOX000168 Neighborhood of MCM5 Neighborhood of MCM5 MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevis (more detail) 60 NA Homo sapiens

MSigDB FEX003254 Stomach Bonelli10 61genes Table 4 Functional grouping of genes that were upregulated and downregulated after ibuprofen treatme (more detail) 60 20548326 Homo sapiens

GeneSigDB WIG000276 CARM1 and Regulation of the Estrogen Receptor Several forms of post-translational modification regulate protein activities. Recently, protein meth (more detail) 34 NA Homo sapiens

MSigDB PEX002139 zf C2H2: Zinc finger, C2H2 type The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines (more detail) 34 NA Homo sapiens

Pfam WIG000729 Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression (more detail) 34 NA Homo sapiens

MSigDB TAX027143 GO:0051702 biological process interaction with symbiont An interaction between two organisms living together in more or less intimate association. The term (more detail) 71 NA Homo sapiens

GOA IEI008578 Protein protein interactors of human gene NAT10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NAT10 (SwissProt ID= (more detail) 48 17535438 Homo sapiens

I2D IEI002473 Protein protein interactors of human gene CHERP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHERP (SwissProt ID= (more detail) 48 17535438 Homo sapiens

I2D IEI000019 Protein protein interactors of human gene AATF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AATF (SwissProt ID=Q (more detail) 48 17535438 Homo sapiens

I2D IEI010210 Protein protein interactors of human gene POLR1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR1A (SwissProt ID (more detail) 48 17535438 Homo sapiens

I2D WAG000188 Glutathione metabolism (more detail) 48 NA Homo sapiens

KEGG IEI005890 Protein protein interactors of human gene HLTF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HLTF (SwissProt ID=Q (more detail) 40 17535438 Homo sapiens

I2D TAX016263 GO:0006342 biological process chromatin silencing Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regi (more detail) 40 NA Homo sapiens

GOA IEI008809 Protein protein interactors of human gene NFYB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFYB (SwissProt ID=P (more detail) 40 17535438 Homo sapiens

I2D TAX034499 GO:2000142 biological process regulation of DNA templated transcription, initiation Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation. (more detail) 37 NA Homo sapiens

GOA WIG001014 Genes involved in Negative regulation of FGFR signaling (more detail) 37 NA Homo sapiens

MSigDB IEI005080 Protein protein interactors of human gene GATA3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GATA3 (SwissProt ID= (more detail) 73 17535438 Homo sapiens

I2D IEI006491 Protein protein interactors of human gene IRF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IRF8 (SwissProt ID=Q (more detail) 73 17535438 Homo sapiens

I2D TAX032834 GO:1903201 biological process regulation of oxidative stress induced cell death Any process that modulates the frequency, rate or extent of oxidative stress-induced cell death. (more detail) 62 NA Homo sapiens

GOA IEI011524 Protein protein interactors of human gene RPL28 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL28 (SwissProt ID= (more detail) 62 17535438 Homo sapiens

I2D WIG000498 Colorectal cancer Classically, colorectal cancer (CRC) has been believed to develop from normal mucosa through the pre (more detail) 62 NA Homo sapiens

MSigDB TAX000289 Genes annotated by the GO term GO:0051329. Progression through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs. (more detail) 62 NA Homo sapiens

MSigDB MAX002582 Genes up regulated in P493 6 cells (Burkitt's lymphoma) induced to express MYC [GeneID=4609]. The proto-oncogene c-myc (myc) encodes a transcription factor (Myc) that promotes growth, proliferat (more detail) 75 NA Homo sapiens

MSigDB IEI014093 Protein protein interactors of human gene TOPBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TOPBP1 (SwissProt ID (more detail) 55 17535438 Homo sapiens

I2D WIG001948 Kit receptor signaling pathway Kit receptor signaling pathway (more detail) 55 NA Homo sapiens

WikiPathway IEI007727 Protein protein interactors of human gene MARS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MARS1 (SwissProt ID= (more detail) 77 17535438 Homo sapiens

I2D TAX026305 GO:0048704 biological process embryonic skeletal system morphogenesis The process in which the anatomical structures of the skeleton are generated and organized during th (more detail) 77 NA Homo sapiens

GOA TAX017341 GO:0008543 biological process fibroblast growth factor receptor signaling pathway The series of molecular signals generated as a consequence of a fibroblast growth factor receptor bi (more detail) 79 NA Homo sapiens

GOA IEI000910 Protein protein interactors of human gene ARNTL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARNTL (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D TAX016564 GO:0006739 biological process NADP metabolic process The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzym (more detail) 30 NA Homo sapiens

GOA TAX016229 GO:0006284 biological process base excision repair In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excisio (more detail) 30 NA Homo sapiens

GOA IEI007568 Protein protein interactors of human gene MAF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAF (SwissProt ID=O7 (more detail) 30 17535438 Homo sapiens

I2D TAX020379 GO:0030212 biological process hyaluronan metabolic process The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hy (more detail) 30 NA Homo sapiens

GOA TAX020906 GO:0031297 biological process replication fork processing The process in which a DNA replication fork that has stalled is restored to a functional state and r (more detail) 30 NA Homo sapiens

GOA TAX028527 GO:0061650 molecular function ubiquitin like protein conjugating enzyme activity Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction (more detail) 30 NA Homo sapiens

GOA TAX025826 GO:0046949 biological process fatty acyl CoA biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative o (more detail) 30 NA Homo sapiens

GOA FAX003057 GSEA KEGG Lung Cancer Tissue Explants (Extracellular Vesicles) Purine Metabolism Top 3 KEGG pathways enriched in lung cancer tissue extract extracellular vesicle particles compared (more detail) 30 32795414 Homo sapiens

Cell TAX013578 GO:0000993 molecular function RNA polymerase II complex binding Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukary (more detail) 30 NA Homo sapiens

GOA TAX013641 GO:0001205 molecular function distal enhancer DNA binding transcription activator activity, RNA polymerase II specific A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA (more detail) 30 NA Homo sapiens

GOA MEX001395 Genes associated with Kinase Inhibitor Indirubin Derivative E804 Genes associated with Kinase Inhibitor Indirubin Derivative E804, curated by the Drug Signature Data (more detail) 30 25990557 Homo sapiens

DSigDB MEX001663 Genes associated with Kinase Inhibitor RAF265 Genes associated with Kinase Inhibitor RAF265, curated by the Drug Signature Database (DSigDB). (more detail) 30 25990557 Homo sapiens

DSigDB TAX016241 GO:0006298 biological process mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds w (more detail) 30 NA Homo sapiens

GOA WIG000802 Genes involved in DNA strand elongation (more detail) 30 NA Homo sapiens

MSigDB TAX013430 GO:0000462 biological process maturation of SSU rRNA from tricistronic rRNA transcript (SSU rRNA, 5.8S rRNA, LSU rRNA) Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molec (more detail) 30 NA Homo sapiens

GOA TAX016288 GO:0006378 biological process mRNA polyadenylation The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA (more detail) 30 NA Homo sapiens

GOA MEX001409 Genes associated with Kinase Inhibitor PP242 Genes associated with Kinase Inhibitor PP242, curated by the Drug Signature Database (DSigDB). (more detail) 30 25990557 Homo sapiens

DSigDB TAX016403 GO:0006536 biological process glutamate metabolic process The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. (more detail) 30 NA Homo sapiens

GOA TAX013292 GO:0000175 molecular function 3' 5' exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule. (more detail) 30 NA Homo sapiens

GOA TAX001160 Genes annotated by the GO term GO:0008238. Catalysis of the cleavage of the terminal or penultimate peptide bond of a peptide chain, releasing a single amino acid or dipeptide. Exopeptidases are classified as aminopeptidases, carboxypeptidases, dipeptidases, and omega peptidases. (more detail) 30 NA Homo sapiens

MSigDB WAG000415 mapkinase signaling pathway The ever evolving mitogen-activated protein kise (MAP kise) pathways consist of four major groupings (more detail) 30 NA Homo sapiens

BioCarta PEX001394 Y phosphatase: Protein tyrosine phosphatase (more detail) 30 NA Homo sapiens

Pfam WEX000043 IL 1 Signaling The genes related to il-1 signaling (immune response) in tumor, immune using next-generation sequenc (more detail) 64 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas TAX014122 GO:0002223 biological process stimulatory C type lectin receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor ca (more detail) 64 NA Homo sapiens

GOA IEI005187 Protein protein interactors of human gene GHR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GHR (SwissProt ID=P1 (more detail) 45 17535438 Homo sapiens

I2D TAX025286 GO:0045815 biological process positive regulation of gene expression, epigenetic Any epigenetic process that activates or increases the rate of gene expression. (more detail) 45 NA Homo sapiens

GOA IEI014542 Protein protein interactors of human gene U2SURP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene U2SURP (SwissProt ID (more detail) 45 17535438 Homo sapiens

I2D TAX026269 GO:0048661 biological process positive regulation of smooth muscle cell proliferation Any process that activates or increases the rate or extent of smooth muscle cell proliferation. (more detail) 81 NA Homo sapiens

GOA TAX019677 GO:0019320 biological process hexose catabolic process The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a (more detail) 50 NA Homo sapiens

GOA TAX024924 GO:0045069 biological process regulation of viral genome replication Any process that modulates the frequency, rate or extent of viral genome replication. (more detail) 83 NA Homo sapiens

GOA IEI007861 Protein protein interactors of human gene MED4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED4 (SwissProt ID=Q (more detail) 85 17535438 Homo sapiens

I2D IEI012597 Protein protein interactors of human gene SMARCD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCD1 (SwissProt I (more detail) 87 17535438 Homo sapiens

I2D IEI010985 Protein protein interactors of human gene RANGAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RANGAP1 (SwissProt I (more detail) 87 17535438 Homo sapiens

I2D IEI009499 Protein protein interactors of human gene PARK7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PARK7 (SwissProt ID= (more detail) 89 17535438 Homo sapiens

I2D FOX000421 Neighborhood of UBE2N Neighborhood of UBE2N ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) in the MORF expressio (more detail) 89 NA Homo sapiens

MSigDB IEI006575 Protein protein interactors of human gene IVNS1ABP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IVNS1ABP (SwissProt (more detail) 66 17535438 Homo sapiens

I2D IEI007809 Protein protein interactors of human gene MCRS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCRS1 (SwissProt ID= (more detail) 66 17535438 Homo sapiens

I2D TAX025308 GO:0045844 biological process positive regulation of striated muscle tissue development Any process that activates or increases the frequency, rate or extent of striated muscle development (more detail) 66 NA Homo sapiens

GOA TAX026257 GO:0048636 biological process positive regulation of muscle organ development Any process that activates, maintains or increases the rate of muscle development. (more detail) 66 NA Homo sapiens

GOA IEI004114 Protein protein interactors of human gene ELP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELP1 (SwissProt ID=O (more detail) 66 17535438 Homo sapiens

I2D TAX000588 Genes annotated by the GO term GO:0051098. Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. (more detail) 57 NA Homo sapiens

MSigDB IEI003575 Protein protein interactors of human gene DKC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DKC1 (SwissProt ID=O (more detail) 57 17535438 Homo sapiens

I2D IEI011695 Protein protein interactors of human gene RTRAF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RTRAF (SwissProt ID= (more detail) 68 17535438 Homo sapiens

I2D MOX016176 Genes associated with Computational Drug Signature kaempferol Genes associated with Computational Drug Signature kaempferol, curated by the Drug Signature Databas (more detail) 68 25990557 Homo sapiens

DSigDB IEI013523 Protein protein interactors of human gene TDG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TDG (SwissProt ID=Q1 (more detail) 42 17535438 Homo sapiens

I2D IEI010821 Protein protein interactors of human gene QKI from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene QKI (SwissProt ID=Q9 (more detail) 59 17535438 Homo sapiens

I2D WIG001071 Genes involved in Phospholipase C mediated cascade (more detail) 52 NA Homo sapiens

MSigDB IEI011728 Protein protein interactors of human gene RYBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RYBP (SwissProt ID=Q (more detail) 47 17535438 Homo sapiens

I2D MOX014802 Genes associated with Computational Drug Signature Resveratrol 13C6 Genes associated with Computational Drug Signature Resveratrol-13C6, curated by the Drug Signature D (more detail) 47 25990557 Homo sapiens

DSigDB IEI010188 Protein protein interactors of human gene POLA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLA1 (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D IEI002857 Protein protein interactors of human gene COPS8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COPS8 (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D MAX001729 Down regulated genes in A2780 cells (ovarian cancer) treated with 17AAG [PubChem=6440175], a chemical with anticancer properties. The promising antitumor activity of 17-allylamino-17-demethoxygeldanamycin (17AAG) results from inhi (more detail) 72 NA Homo sapiens

MSigDB TAX030893 GO:0097502 biological process mannosylation The covalent attachment of a mannose residue to a substrate molecule. (more detail) 33 NA Homo sapiens

GOA IEI010628 Protein protein interactors of human gene PSMA8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMA8 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D WIG000869 Genes involved in Global Genomic NER (GG NER) (more detail) 33 NA Homo sapiens

MSigDB MOX015219 Genes associated with Computational Drug Signature SU9516 Genes associated with Computational Drug Signature SU9516, curated by the Drug Signature Database (D (more detail) 33 25990557 Homo sapiens

DSigDB WIG001166 Genes involved in RNA Polymerase III Transcription (more detail) 33 NA Homo sapiens

MSigDB IEI008375 Protein protein interactors of human gene MUC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MUC1 (SwissProt ID=P (more detail) 39 17535438 Homo sapiens

I2D IEI000560 Protein protein interactors of human gene ANAPC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC4 (SwissProt ID (more detail) 39 17535438 Homo sapiens

I2D IEI013608 Protein protein interactors of human gene TFDP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TFDP1 (SwissProt ID= (more detail) 39 17535438 Homo sapiens

I2D IEI009184 Protein protein interactors of human gene NUP93 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUP93 (SwissProt ID= (more detail) 74 17535438 Homo sapiens

I2D TAX027538 GO:0055024 biological process regulation of cardiac muscle tissue development Any process that modulates the frequency, rate or extent of cardiac muscle tissue development. (more detail) 74 NA Homo sapiens

GOA WIG001220 Genes involved in Signaling by TGF beta Receptor Complex (more detail) 61 NA Homo sapiens

MSigDB TAX020784 GO:0031062 biological process positive regulation of histone methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of me (more detail) 36 NA Homo sapiens

GOA IEI013221 Protein protein interactors of human gene SUPT3H from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUPT3H (SwissProt ID (more detail) 36 17535438 Homo sapiens

I2D TAX024008 GO:0042769 biological process DNA damage response, detection of DNA damage The series of events required to receive a stimulus indicating DNA damage has occurred and convert i (more detail) 36 NA Homo sapiens

GOA IEI007193 Protein protein interactors of human gene LDB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LDB1 (SwissProt ID=Q (more detail) 36 17535438 Homo sapiens

I2D TAX001429 Genes annotated by the GO term GO:0016741. Catalysis of the transfer of a one carbon group from one compound (donor) to another (acceptor). (more detail) 36 NA Homo sapiens

MSigDB IEI003387 Protein protein interactors of human gene DDB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDB2 (SwissProt ID=Q (more detail) 54 17535438 Homo sapiens

I2D IEI006437 Protein protein interactors of human gene INTS6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS6 (SwissProt ID= (more detail) 54 17535438 Homo sapiens

I2D MOX004264 Genes associated with Computational Drug Signature dl Thioctic acid Genes associated with Computational Drug Signature dl-Thioctic acid, curated by the Drug Signature D (more detail) 54 25990557 Homo sapiens

DSigDB WIG001914 RANKL/RANK Signaling Pathway RANKL/RANK Signaling Pathway (more detail) 54 NA Homo sapiens

WikiPathway TAX000270 Genes annotated by the GO term GO:0002520. The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. (more detail) 78 NA Homo sapiens

MSigDB TAX022791 GO:0035264 biological process multicellular organism growth The increase in size or mass of an entire multicellular organism, as opposed to cell growth. (more detail) 78 NA Homo sapiens

GOA TAX013244 GO:0000079 biological process regulation of cyclin dependent protein serine/threonine kinase activity Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonin (more detail) 86 NA Homo sapiens

GOA WIG000474 Apoptosis Apoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue (more detail) 86 NA Homo sapiens

MSigDB TAX020772 GO:0031047 biological process gene silencing by RNA Any process in which RNA molecules inactivate expression of target genes. (more detail) 44 NA Homo sapiens

GOA MOX002432 Genes associated with Computational Drug Signature lactacystin Genes associated with Computational Drug Signature lactacystin, curated by the Drug Signature Databa (more detail) 49 25990557 Homo sapiens

DSigDB FAX003054 GSEA Hallmark Lung Cancer Tissue Explants (Extracellular Vesicles) MYC Targets Top 3 pathways enriched in lung cancer tissue extract extracellular vesicle particles compared to ma (more detail) 49 32795414 Homo sapiens

Cell WEX000044 IL 17 Signaling The genes related to il-17 signaling (immune response) in immune using next-generation sequencer (NG (more detail) 49 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI011115 Protein protein interactors of human gene RBPJ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBPJ (SwissProt ID=Q (more detail) 49 17535438 Homo sapiens

I2D WAG000811 Fc epsilon RI signaling pathway Fc epsilon RI-mediated sigling pathways in mast cells are initiated by the interaction of antigen (A (more detail) 65 NA Homo sapiens

KEGG TAX033026 GO:1903578 biological process regulation of ATP metabolic process Any process that modulates the frequency, rate or extent of ATP metabolic process. (more detail) 65 NA Homo sapiens

GOA IEI006179 Protein protein interactors of human gene IFIT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFIT3 (SwissProt ID= (more detail) 65 17535438 Homo sapiens

I2D TAX017490 GO:0009074 biological process aromatic amino acid family catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino (more detail) 29 NA Homo sapiens

GOA TAX016578 GO:0006760 biological process folic acid containing compound metabolic process The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group (more detail) 29 NA Homo sapiens

GOA TAX017105 GO:0008175 molecular function tRNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule. (more detail) 29 NA Homo sapiens

GOA TAX021561 GO:0032452 molecular function histone demethylase activity Catalysis of the removal of a methyl group from a histone. (more detail) 29 NA Homo sapiens

GOA TAX016318 GO:0006418 biological process tRNA aminoacylation for protein translation The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of t (more detail) 29 NA Homo sapiens

GOA TAX027065 GO:0051568 biological process histone H3 K4 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of t (more detail) 29 NA Homo sapiens

GOA TAX023707 GO:0042168 biological process heme metabolic process The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (t (more detail) 29 NA Homo sapiens

GOA TAX029250 GO:0071007 cellular component U2 type catalytic step 2 spliceosome A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in wh (more detail) 29 NA Homo sapiens

GOA TAX017674 GO:0009394 biological process 2' deoxyribonucleotide metabolic process The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'- (more detail) 29 NA Homo sapiens

GOA TAX029291 GO:0071108 biological process protein K48 linked deubiquitination A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquiti (more detail) 29 NA Homo sapiens

GOA TAX017910 GO:0010390 biological process histone monoubiquitination The modification of histones by addition of a single ubiquitin group. (more detail) 29 NA Homo sapiens

GOA TAX019471 GO:0018146 biological process keratan sulfate biosynthetic process The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglyc (more detail) 29 NA Homo sapiens

GOA IEI009030 Protein protein interactors of human gene NR2E3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR2E3 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D MEX001410 Genes associated with Kinase Inhibitor NG25 Genes associated with Kinase Inhibitor NG25, curated by the Drug Signature Database (DSigDB). (more detail) 29 25990557 Homo sapiens

DSigDB WAG000987 Cyanoamino acid metabolism (more detail) 29 NA Homo sapiens

KEGG TAX016504 GO:0006658 biological process phosphatidylserine metabolic process The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophosphol (more detail) 29 NA Homo sapiens

GOA MEX002028 Genes associated with Kinase Inhibitor CHEMBL1673039 Genes associated with Kinase Inhibitor CHEMBL1673039, curated by the Drug Signature Database (DSigDB (more detail) 29 25990557 Homo sapiens

DSigDB PEX001905 UQ con: Ubiquitin conjugating enzyme Proteins destined for proteasome-mediated degradation may be ubiquitinated. Ubiquitination follows c (more detail) 29 NA Homo sapiens

Pfam TAX000426 Genes annotated by the GO term GO:0044270. The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds. (more detail) 29 NA Homo sapiens

MSigDB MEX002250 Genes associated with Kinase Inhibitor BI D1870 Genes associated with Kinase Inhibitor BI-D1870, curated by the Drug Signature Database (DSigDB). (more detail) 29 25990557 Homo sapiens

DSigDB MEX002239 Genes associated with Kinase Inhibitor Kinome 635 Genes associated with Kinase Inhibitor Kinome_635, curated by the Drug Signature Database (DSigDB). (more detail) 29 25990557 Homo sapiens

DSigDB MEX001623 Genes associated with Kinase Inhibitor AT7519 Genes associated with Kinase Inhibitor AT7519, curated by the Drug Signature Database (DSigDB). (more detail) 29 25990557 Homo sapiens

DSigDB TAX000792 Genes annotated by the GO term GO:0006367. Processes involved in starting transcription from the RNA polymerase II promoter. (more detail) 29 NA Homo sapiens

MSigDB WIG000957 Genes involved in Keratan sulfate/keratin metabolism (more detail) 29 NA Homo sapiens

MSigDB MEX001589 Genes associated with Kinase Inhibitor dorsomorphin Genes associated with Kinase Inhibitor dorsomorphin, curated by the Drug Signature Database (DSigDB) (more detail) 29 25990557 Homo sapiens

DSigDB TAX016237 GO:0006294 biological process nucleotide excision repair, preincision complex assembly The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein comple (more detail) 29 NA Homo sapiens

GOA IEI000858 Protein protein interactors of human gene ARID1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARID1A (SwissProt ID (more detail) 56 17535438 Homo sapiens

I2D IEI014129 Protein protein interactors of human gene TPI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TPI1 (SwissProt ID=P (more detail) 56 17535438 Homo sapiens

I2D IEI004369 Protein protein interactors of human gene EXOSC8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXOSC8 (SwissProt ID (more detail) 56 17535438 Homo sapiens

I2D MOX000844 Genes associated with Computational Drug Signature Fisetin Genes associated with Computational Drug Signature Fisetin, curated by the Drug Signature Database ( (more detail) 56 25990557 Homo sapiens

DSigDB TAX014120 GO:0002220 biological process innate immune response activating cell surface receptor signaling pathway Any series of molecular signals leading to activation of the innate immune response generated as a c (more detail) 67 NA Homo sapiens

GOA FOX000020 Neighborhood of CBFB Neighborhood of CBFB core-binding factor, beta subunit in the GCM expression compendium (more detail) 67 NA Homo sapiens

MSigDB WIG001620 PDGF Pathway PDGF Pathway (more detail) 67 NA Homo sapiens

Protein Lounge WEX000108 VEGF Signaling The genes related to vegf signaling (signaling pathways) in tumor, stroma using next-generation sequ (more detail) 69 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI001427 Protein protein interactors of human gene BRD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRD4 (SwissProt ID=O (more detail) 69 17535438 Homo sapiens

I2D IEI007870 Protein protein interactors of human gene MEF2D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEF2D (SwissProt ID= (more detail) 58 17535438 Homo sapiens

I2D MOX004923 Genes associated with Computational Drug Signature nocodazole Genes associated with Computational Drug Signature nocodazole, curated by the Drug Signature Databas (more detail) 58 25990557 Homo sapiens

DSigDB TAX019208 GO:0016776 molecular function phosphotransferase activity, phosphate group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate (more detail) 41 NA Homo sapiens

GOA IEI015174 Protein protein interactors of human gene YTHDF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YTHDF2 (SwissProt ID (more detail) 41 17535438 Homo sapiens

I2D MOX003769 Genes associated with Computational Drug Signature busulfan Genes associated with Computational Drug Signature busulfan, curated by the Drug Signature Database (more detail) 41 25990557 Homo sapiens

DSigDB IEI004306 Protein protein interactors of human gene ESRRA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ESRRA (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D TAX028841 GO:0070279 molecular function vitamin B6 binding Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxa (more detail) 51 NA Homo sapiens

GOA TAX020347 GO:0030170 molecular function pyridoxal phosphate binding Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)- (more detail) 51 NA Homo sapiens

GOA MOX016821 Genes associated with Computational Drug Signature sphingosine Genes associated with Computational Drug Signature sphingosine, curated by the Drug Signature Databa (more detail) 71 25990557 Homo sapiens

DSigDB IEI006779 Protein protein interactors of human gene KHDRBS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KHDRBS2 (SwissProt I (more detail) 73 17535438 Homo sapiens

I2D IEI009090 Protein protein interactors of human gene NSUN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NSUN2 (SwissProt ID= (more detail) 73 17535438 Homo sapiens

I2D TAX001199 Genes annotated by the GO term GO:0016798. Catalysis of the hydrolysis of any glycosyl bond. (more detail) 46 NA Homo sapiens

MSigDB MOX004710 Genes associated with Computational Drug Signature T 2 TOXIN Genes associated with Computational Drug Signature T-2 TOXIN, curated by the Drug Signature Database (more detail) 46 25990557 Homo sapiens

DSigDB IEI003325 Protein protein interactors of human gene DCAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCAF1 (SwissProt ID= (more detail) 60 17535438 Homo sapiens

I2D WIG001463 Cyclins and Cell Cycle Regulation Cyclins and Cell Cycle Regulation (more detail) 60 NA Homo sapiens

Protein Lounge WIG000828 Genes involved in ER Phagosome pathway (more detail) 60 NA Homo sapiens

MSigDB WAG000806 VEGF signaling pathway There is now much evidence that VEGFR-2 is the major mediator of VEGF-driven responses in endothelia (more detail) 60 NA Homo sapiens

KEGG IEI009257 Protein protein interactors of human gene OGT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OGT (SwissProt ID=O1 (more detail) 75 17535438 Homo sapiens

I2D MOX004779 Genes associated with Computational Drug Signature TOSYLPHENYLALANYL CHLOROMETHYL KETONE Genes associated with Computational Drug Signature TOSYLPHENYLALANYL CHLOROMETHYL KETONE, curated by (more detail) 75 25990557 Homo sapiens

DSigDB MOX017357 Genes associated with Computational Drug Signature myricetin Genes associated with Computational Drug Signature myricetin, curated by the Drug Signature Database (more detail) 75 25990557 Homo sapiens

DSigDB FAX000331 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif TAANNYSGCG. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif TAANNYSGCG. (more detail) 75 NA Homo sapiens

MSigDB IEI012974 Protein protein interactors of human gene SRP14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRP14 (SwissProt ID= (more detail) 77 17535438 Homo sapiens

I2D WIG001472 EGF Pathway EGF Pathway (more detail) 77 NA Homo sapiens

Protein Lounge IEI001208 Protein protein interactors of human gene BACH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BACH1 (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D IEI011157 Protein protein interactors of human gene RECQL5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RECQL5 (SwissProt ID (more detail) 38 17535438 Homo sapiens

I2D TAX030871 GO:0097472 molecular function cyclin dependent protein kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the rea (more detail) 38 NA Homo sapiens

GOA IEI013542 Protein protein interactors of human gene TECR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TECR (SwissProt ID=Q (more detail) 38 17535438 Homo sapiens

I2D IEI014503 Protein protein interactors of human gene TWIST1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TWIST1 (SwissProt ID (more detail) 38 17535438 Homo sapiens

I2D WAG000033 IL2 mediated signaling events (more detail) 38 NA Homo sapiens

NCI-Nature Curated IEI007856 Protein protein interactors of human gene MED27 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED27 (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D TAX013595 GO:0001046 molecular function core promoter sequence specific DNA binding Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter re (more detail) 32 NA Homo sapiens

GOA MEX001278 Genes associated with Kinase Inhibitor AGN PC 0INJ9Y Genes associated with Kinase Inhibitor AGN-PC-0INJ9Y, curated by the Drug Signature Database (DSigDB (more detail) 32 25990557 Homo sapiens

DSigDB WIG000402 PDGF Signaling Pathway Platelet Derived Growth Factor (PDGF) plays a critical role in cellular proliferation and developmen (more detail) 32 NA Homo sapiens

MSigDB IEI011767 Protein protein interactors of human gene SAFB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SAFB (SwissProt ID=Q (more detail) 79 17535438 Homo sapiens

I2D TAX032676 GO:1902882 biological process regulation of response to oxidative stress Any process that modulates the frequency, rate or extent of response to oxidative stress. (more detail) 81 NA Homo sapiens

GOA IEI002683 Protein protein interactors of human gene CLU from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLU (SwissProt ID=P1 (more detail) 83 17535438 Homo sapiens

I2D WAG000803 TGF beta signaling pathway The transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and (more detail) 83 NA Homo sapiens

KEGG IEI002474 Protein protein interactors of human gene CHFR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHFR (SwissProt ID=Q (more detail) 53 17535438 Homo sapiens

I2D IEI008194 Protein protein interactors of human gene MRPL23 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPL23 (SwissProt ID (more detail) 53 17535438 Homo sapiens

I2D FEX000772 Breast Wood10 71genes CellCyle Supplementary Table 3A: All significantly altered genes related to cell cycle (by KEGG pathway analy (more detail) 53 20103679 Homo sapiens

GeneSigDB FEX000775 Breast Wood10 71genes FoldChange Supplementary Table 3D: All genes with fold-change (more detail) 53 20103679 Homo sapiens

GeneSigDB IEI007879 Protein protein interactors of human gene MEIS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEIS1 (SwissProt ID= (more detail) 35 17535438 Homo sapiens

I2D TAX019235 GO:0016814 molecular function hydrolase activity, acting on carbon nitrogen (but not peptide) bonds, in cyclic amidines Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound (more detail) 35 NA Homo sapiens

GOA MEX000819 Genes associated with Approved Drug bortezomib Genes associated with Approved Drug bortezomib, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens

DSigDB TAX000740 Genes annotated by the GO term GO:0000375. Splicing of RNA via a series of two transesterification reactions. (more detail) 35 NA Homo sapiens

MSigDB TAX001247 Genes annotated by the GO term GO:0008168. Catalysis of the transfer of a methyl group to an acceptor molecule. (more detail) 35 NA Homo sapiens

MSigDB WIG000484 Base excision repair Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small (more detail) 35 NA Homo sapiens

MSigDB WIG000483 Basal transcription factors (more detail) 35 NA Homo sapiens

MSigDB IEI007869 Protein protein interactors of human gene MEF2C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEF2C (SwissProt ID= (more detail) 64 17535438 Homo sapiens

I2D IEI003438 Protein protein interactors of human gene DDX58 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX58 (SwissProt ID= (more detail) 64 17535438 Homo sapiens

I2D IEI014584 Protein protein interactors of human gene UBE2M from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2M (SwissProt ID= (more detail) 64 17535438 Homo sapiens

I2D TAX023841 GO:0042440 biological process pigment metabolic process The chemical reactions and pathways involving pigment, any general or particular coloring matter in (more detail) 64 NA Homo sapiens

GOA TAX032329 GO:1901992 biological process positive regulation of mitotic cell cycle phase transition Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase tr (more detail) 64 NA Homo sapiens

GOA IEI007885 Protein protein interactors of human gene MEN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEN1 (SwissProt ID=O (more detail) 64 17535438 Homo sapiens

I2D WIG001591 NGF Pathway NGF Pathway (more detail) 64 NA Homo sapiens

Protein Lounge IEI009332 Protein protein interactors of human gene ORC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ORC2 (SwissProt ID=Q (more detail) 48 17535438 Homo sapiens

I2D TAX024379 GO:0043470 biological process regulation of carbohydrate catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways res (more detail) 48 NA Homo sapiens

GOA WIG000035 Ceramide signaling pathway (more detail) 48 NA Homo sapiens

MSigDB IEI004370 Protein protein interactors of human gene EXOSC9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXOSC9 (SwissProt ID (more detail) 43 17535438 Homo sapiens

I2D IEI007980 Protein protein interactors of human gene MID1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MID1 (SwissProt ID=O (more detail) 43 17535438 Homo sapiens

I2D IEI012701 Protein protein interactors of human gene SNRPN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNRPN (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D IEI004253 Protein protein interactors of human gene ERCC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERCC6 (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D IEI004363 Protein protein interactors of human gene EXOSC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXOSC2 (SwissProt ID (more detail) 43 17535438 Homo sapiens

I2D MOX016287 Genes associated with Computational Drug Signature GNF Pf 4325 Genes associated with Computational Drug Signature GNF-Pf-4325, curated by the Drug Signature Databa (more detail) 43 25990557 Homo sapiens

DSigDB WIG001682 SUMO Pathway SUMO Pathway (more detail) 55 NA Homo sapiens

Protein Lounge MOX003077 Genes associated with Computational Drug Signature Tanespimycin Genes associated with Computational Drug Signature Tanespimycin, curated by the Drug Signature Datab (more detail) 55 25990557 Homo sapiens

DSigDB WIG001766 LPS Stimulated MAPK Signaling LPS Stimulated MAPK Signaling (more detail) 55 NA Homo sapiens

Protein Lounge IEI009614 Protein protein interactors of human gene PCMT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCMT1 (SwissProt ID= (more detail) 66 17535438 Homo sapiens

I2D TAX032775 GO:1903051 biological process negative regulation of proteolysis involved in cellular protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in (more detail) 66 NA Homo sapiens

GOA TAX015317 GO:0004683 molecular function calmodulin dependent protein kinase activity Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a pro (more detail) 28 NA Homo sapiens

GOA TAX025470 GO:0046134 biological process pyrimidine nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of one of a family of organic molecul (more detail) 28 NA Homo sapiens

GOA TAX028983 GO:0070536 biological process protein K63 linked deubiquitination A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquiti (more detail) 28 NA Homo sapiens

GOA TAX023826 GO:0042417 biological process dopamine metabolic process The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metab (more detail) 28 NA Homo sapiens

GOA TAX022594 GO:0034661 biological process ncRNA catabolic process The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs (more detail) 28 NA Homo sapiens

GOA TAX017209 GO:0008334 biological process histone mRNA metabolic process The chemical reactions and pathways involving an mRNA encoding a histone. (more detail) 28 NA Homo sapiens

GOA IEI007851 Protein protein interactors of human gene MED22 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED22 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI007833 Protein protein interactors of human gene MECOM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MECOM (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D TAX028519 GO:0061631 molecular function ubiquitin conjugating enzyme activity Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y (more detail) 28 NA Homo sapiens

GOA TAX019098 GO:0016572 biological process histone phosphorylation The modification of histones by addition of phosphate groups. (more detail) 28 NA Homo sapiens

GOA TAX019525 GO:0018345 biological process protein palmitoylation The covalent attachment of a palmitoyl group to a protein. (more detail) 28 NA Homo sapiens

GOA TAX033891 GO:1905348 cellular component endonuclease complex A protein complex which is capable of endonuclease activity. (more detail) 28 NA Homo sapiens

GOA TAX019489 GO:0018200 biological process peptidyl glutamic acid modification The modification of peptidyl-glutamic acid. (more detail) 28 NA Homo sapiens

GOA TAX023721 GO:0042219 biological process cellular modified amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids (more detail) 28 NA Homo sapiens

GOA TAX028715 GO:0070076 biological process histone lysine demethylation The modification of a histone by the removal of a methyl group from a lysine residue. (more detail) 28 NA Homo sapiens

GOA TAX023105 GO:0035825 biological process homologous recombination A DNA recombination process that results in the equal exchange of genetic material between the recom (more detail) 28 NA Homo sapiens

GOA TAX024484 GO:0043628 biological process ncRNA 3' end processing Any process involved in forming the mature 3' end of a non-coding RNA molecule. (more detail) 28 NA Homo sapiens

GOA TAX032554 GO:1902555 cellular component endoribonuclease complex A protein complex which is capable of endoribonuclease activity. (more detail) 28 NA Homo sapiens

GOA TAX029226 GO:0070979 biological process protein K11 linked ubiquitination A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubi (more detail) 28 NA Homo sapiens

GOA TAX016790 GO:0007131 biological process reciprocal meiotic recombination The cell cycle process in which double strand breaks are formed and repaired through a double Hollid (more detail) 28 NA Homo sapiens

GOA TAX028893 GO:0070371 biological process ERK1 and ERK2 cascade An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) an (more detail) 28 NA Homo sapiens

GOA WAG000071 Formation of transcription coupled NER (TC NER) repair complex (more detail) 28 NA Homo sapiens

Reactome WAG000321 Transcription coupled NER (TC NER) (more detail) 28 NA Homo sapiens

Reactome WAG000080 Dual incision reaction in TC NER (more detail) 28 NA Homo sapiens

Reactome MEX001704 Genes associated with Kinase Inhibitor ITK inhibitor Genes associated with Kinase Inhibitor ITK inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 28 25990557 Homo sapiens

DSigDB TAX001145 Genes annotated by the GO term GO:0003690. Interacting selectively with double stranded DNA. (more detail) 28 NA Homo sapiens

MSigDB TAX016278 GO:0006361 biological process transcription initiation from RNA polymerase I promoter Any process involved in the assembly of the RNA polymerase I preinitiation complex (PIC) at an RNA p (more detail) 28 NA Homo sapiens

GOA WIG000409 Proteasome Complex Attachment of the ubiquitin peptide to proteins targets them for proteolytic degradation by a comple (more detail) 28 NA Homo sapiens

MSigDB WIG000024 BARD1 signaling events (more detail) 28 NA Homo sapiens

MSigDB TAX015031 GO:0004181 molecular function metallocarboxypeptidase activity Catalysis of the hydrolysis of C-terminal amino acid residues from a polypeptide chain by a mechanis (more detail) 28 NA Homo sapiens

GOA MEX002007 Genes associated with Kinase Inhibitor GSK 650394 Genes associated with Kinase Inhibitor GSK 650394, curated by the Drug Signature Database (DSigDB). (more detail) 28 25990557 Homo sapiens

DSigDB WIG001191 Genes involved in SHC mediated cascade (more detail) 28 NA Homo sapiens

MSigDB TAX016212 GO:0006261 biological process DNA dependent DNA replication A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases (more detail) 28 NA Homo sapiens

GOA TAX000765 Genes annotated by the GO term GO:0006665. The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long chain amine diol sphingosine or a closely related base (a sphingoid). (more detail) 28 NA Homo sapiens

MSigDB TAX016386 GO:0006517 biological process protein deglycosylation The removal of sugar residues from a glycosylated protein. (more detail) 28 NA Homo sapiens

GOA MEX001110 Genes associated with Approved Drug pazopanib hydrochloride Genes associated with Approved Drug pazopanib hydrochloride, curated by the Drug Signature Database (more detail) 28 25990557 Homo sapiens

DSigDB WIG000615 RNA polymerase (more detail) 28 NA Homo sapiens

MSigDB IEI009747 Protein protein interactors of human gene PELP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PELP1 (SwissProt ID= (more detail) 68 17535438 Homo sapiens

I2D MAX002979 Cluster 1: genes up regulated by RB1, CDNK2A [GeneID=1029;5925], and one of the E2Fs (E2F1, E2F2, or E2F3 [GeneID=1869;1870;1871]). Deregulation of the retinoblastoma protein (pRB) pathway is a hallmark of human cancer. The core mem (more detail) 68 NA Homo sapiens

MSigDB IEI014565 Protein protein interactors of human gene UBE2C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2C (SwissProt ID= (more detail) 57 17535438 Homo sapiens

I2D IEI002656 Protein protein interactors of human gene CLK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLK3 (SwissProt ID=P (more detail) 57 17535438 Homo sapiens

I2D FOX000529 Genes in the cancer module 199 (more detail) 57 NA Homo sapiens

MSigDB TAX014020 GO:0002039 molecular function p53 binding Interacting selectively and non-covalently with one of the p53 family of proteins. (more detail) 70 NA Homo sapiens

GOA FOX000625 Genes in the cancer module 308 (more detail) 70 NA Homo sapiens

MSigDB IEI002115 Protein protein interactors of human gene CD2BP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CD2BP2 (SwissProt ID (more detail) 72 17535438 Homo sapiens

I2D IEI013571 Protein protein interactors of human gene TERT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TERT (SwissProt ID=O (more detail) 72 17535438 Homo sapiens

I2D IEI013186 Protein protein interactors of human gene SUB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUB1 (SwissProt ID=P (more detail) 40 17535438 Homo sapiens

I2D IEI002981 Protein protein interactors of human gene CREM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CREM (SwissProt ID=Q (more detail) 40 17535438 Homo sapiens

I2D IEI007617 Protein protein interactors of human gene MALT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MALT1 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D WEX000031 FGFR Signaling The genes related to fgfr signaling (signaling pathways) in tumor using next-generation sequencer (N (more detail) 40 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI009027 Protein protein interactors of human gene NR2C2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR2C2 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D IEI011709 Protein protein interactors of human gene RUNX3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RUNX3 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D IEI013967 Protein protein interactors of human gene TMOD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TMOD3 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D TAX026212 GO:0048538 biological process thymus development The process whose specific outcome is the progression of the thymus over time, from its formation to (more detail) 40 NA Homo sapiens

GOA IEI011609 Protein protein interactors of human gene RPS6KB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS6KB1 (SwissProt I (more detail) 74 17535438 Homo sapiens

I2D IEI004264 Protein protein interactors of human gene ERH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERH (SwissProt ID=P8 (more detail) 74 17535438 Homo sapiens

I2D IEI001788 Protein protein interactors of human gene CAPZB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAPZB (SwissProt ID= (more detail) 74 17535438 Homo sapiens

I2D TAX000256 Genes annotated by the GO term GO:0048534. The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. (more detail) 74 NA Homo sapiens

MSigDB IEI007957 Protein protein interactors of human gene MGMT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MGMT (SwissProt ID=P (more detail) 76 17535438 Homo sapiens

I2D MOX016229 Genes associated with Computational Drug Signature cytarabine Genes associated with Computational Drug Signature cytarabine, curated by the Drug Signature Databas (more detail) 76 25990557 Homo sapiens

DSigDB FAX000229 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif ACAWNRNSRCGG. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif ACAWNRNSRCGG (more detail) 59 NA Homo sapiens

MSigDB TAX020194 GO:0022617 biological process extracellular matrix disassembly A process that results in the breakdown of the extracellular matrix. (more detail) 59 NA Homo sapiens

GOA WEX000091 RNA Sensing The genes related to rna sensing (innate immunity) in tumor using next-generation sequencer (NGS) re (more detail) 59 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI012239 Protein protein interactors of human gene SIRT5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIRT5 (SwissProt ID= (more detail) 78 17535438 Homo sapiens

I2D TAX032908 GO:1903363 biological process negative regulation of cellular protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabo (more detail) 78 NA Homo sapiens

GOA TAX026875 GO:0051219 molecular function phosphoprotein binding Interacting selectively and non-covalently with a phosphorylated protein. (more detail) 78 NA Homo sapiens

GOA IEI003051 Protein protein interactors of human gene CSK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSK (SwissProt ID=P4 (more detail) 78 17535438 Homo sapiens

I2D WAG000606 Apoptosis Apoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue (more detail) 78 NA Homo sapiens

KEGG MOX017621 Genes associated with Computational Drug Signature mitomycin C Genes associated with Computational Drug Signature mitomycin C, curated by the Drug Signature Databa (more detail) 78 25990557 Homo sapiens

DSigDB IEI006637 Protein protein interactors of human gene KAT8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KAT8 (SwissProt ID=Q (more detail) 45 17535438 Homo sapiens

I2D WAG000253 FGF signaling pathway (more detail) 45 NA Homo sapiens

NCI-Nature Curated WAG001062 Calcineurin regulated NFAT dependent transcription in lymphocytes (more detail) 45 NA Homo sapiens

NCI-Nature Curated MOX016073 Genes associated with Computational Drug Signature Gallic acid Genes associated with Computational Drug Signature Gallic acid, curated by the Drug Signature Databa (more detail) 80 25990557 Homo sapiens

DSigDB TAX020133 GO:0021953 biological process central nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose (more detail) 80 NA Homo sapiens

GOA IEI010341 Protein protein interactors of human gene PPP1R12A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R12A (SwissProt (more detail) 61 17535438 Homo sapiens

I2D IEI003340 Protein protein interactors of human gene DCAF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCAF7 (SwissProt ID= (more detail) 61 17535438 Homo sapiens

I2D MOX004020 Genes associated with Computational Drug Signature dopamine Genes associated with Computational Drug Signature dopamine, curated by the Drug Signature Database (more detail) 61 25990557 Homo sapiens

DSigDB IEI015027 Protein protein interactors of human gene WDR82 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR82 (SwissProt ID= (more detail) 52 17535438 Homo sapiens

I2D IEI014592 Protein protein interactors of human gene UBE2S from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2S (SwissProt ID= (more detail) 52 17535438 Homo sapiens

I2D IEI011377 Protein protein interactors of human gene RNF111 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF111 (SwissProt ID (more detail) 52 17535438 Homo sapiens

I2D WAG001478 Signaling events mediated by Stem cell factor receptor (c Kit) (more detail) 52 NA Homo sapiens

NCI-Nature Curated WIG000234 p38 MAPK Pathway na (more detail) 37 NA Homo sapiens

MSigDB TAX015324 GO:0004693 molecular function cyclin dependent protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein (more detail) 37 NA Homo sapiens

GOA TAX017975 GO:0010569 biological process regulation of double strand break repair via homologous recombination Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand (more detail) 37 NA Homo sapiens

GOA IEI008423 Protein protein interactors of human gene MYCN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYCN (SwissProt ID=P (more detail) 31 17535438 Homo sapiens

I2D TAX030904 GO:0097526 cellular component spliceosomal tri snRNP complex A spliceosomal snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and as (more detail) 31 NA Homo sapiens

GOA WIG000309 EGF Signaling Pathway The epidermal growth factor (EGF) peptide induces cellular proliferation through the EGF receptor, w (more detail) 31 NA Homo sapiens

MSigDB WIG000910 Genes involved in HS GAG biosynthesis (more detail) 31 NA Homo sapiens

MSigDB WAG000260 BCR signaling pathway (more detail) 63 NA Homo sapiens

NCI-Nature Curated TAX021954 GO:0033047 biological process regulation of mitotic sister chromatid segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation during mito (more detail) 63 NA Homo sapiens

GOA IEI014755 Protein protein interactors of human gene USP14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP14 (SwissProt ID= (more detail) 63 17535438 Homo sapiens

I2D IEI008012 Protein protein interactors of human gene MITF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MITF (SwissProt ID=O (more detail) 34 17535438 Homo sapiens

I2D TAX017228 GO:0008376 molecular function acetylgalactosaminyltransferase activity Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an (more detail) 34 NA Homo sapiens

GOA IEI004877 Protein protein interactors of human gene FOXM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXM1 (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D TAX026271 GO:0048663 biological process neuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop i (more detail) 34 NA Homo sapiens

GOA WIG001969 p38 MAPK Signaling Pathway p38 MAPK Signaling Pathway (more detail) 34 NA Homo sapiens

WikiPathway IEI010191 Protein protein interactors of human gene POLD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLD1 (SwissProt ID= (more detail) 65 17535438 Homo sapiens

I2D IEI004983 Protein protein interactors of human gene G3BP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene G3BP2 (SwissProt ID= (more detail) 65 17535438 Homo sapiens

I2D WIG000522 Glioma Glioblastoma multiforme (GBM) formation is either de novo (primary GBMs) or due to the progression o (more detail) 65 NA Homo sapiens

MSigDB WAG001433 Pancreatic cancer Infiltrating ductal adenocarcinoma is the most common maligncy of the pancreas. When most investigat (more detail) 65 NA Homo sapiens

KEGG MOX003979 Genes associated with Computational Drug Signature Cardidigin Genes associated with Computational Drug Signature Cardidigin, curated by the Drug Signature Databas (more detail) 47 25990557 Homo sapiens

DSigDB WAG001266 Ceramide signaling pathway (more detail) 47 NA Homo sapiens

NCI-Nature Curated IEI005157 Protein protein interactors of human gene GFI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GFI1 (SwissProt ID=Q (more detail) 47 17535438 Homo sapiens

I2D IEI008412 Protein protein interactors of human gene MYBL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYBL2 (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D IEI010325 Protein protein interactors of human gene PPM1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPM1B (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D IEI010291 Protein protein interactors of human gene PPARA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPARA (SwissProt ID= (more detail) 54 17535438 Homo sapiens

I2D WIG002018 ErbB signaling pathway ErbB signaling pathway (more detail) 54 NA Homo sapiens

WikiPathway MOX015999 Genes associated with Computational Drug Signature 1,10 phenanthroline Genes associated with Computational Drug Signature 1,10-phenanthroline, curated by the Drug Signatur (more detail) 54 25990557 Homo sapiens

DSigDB MOX000778 Genes associated with Computational Drug Signature Indole 3 carbinol Genes associated with Computational Drug Signature Indole-3-carbinol, curated by the Drug Signature (more detail) 54 25990557 Homo sapiens

DSigDB WIG002009 TGF Beta Signaling Pathway TGF Beta Signaling Pathway (more detail) 54 NA Homo sapiens

WikiPathway IEI010637 Protein protein interactors of human gene PSMB8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMB8 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D IEI003043 Protein protein interactors of human gene CSF2RB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSF2RB (SwissProt ID (more detail) 42 17535438 Homo sapiens

I2D IEI015117 Protein protein interactors of human gene XPA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XPA (SwissProt ID=P2 (more detail) 42 17535438 Homo sapiens

I2D WIG001801 BMP Pathway BMP Pathway (more detail) 42 NA Homo sapiens

Protein Lounge IEI005922 Protein protein interactors of human gene HNF1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNF1A (SwissProt ID= (more detail) 67 17535438 Homo sapiens

I2D TAX027220 GO:0051851 biological process modification by host of symbiont morphology or physiology The process in which an organism effects a change in the structure or processes of a symbiont organi (more detail) 67 NA Homo sapiens

GOA IEI014677 Protein protein interactors of human gene UIMC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UIMC1 (SwissProt ID= (more detail) 67 17535438 Homo sapiens

I2D TAX017834 GO:0010001 biological process glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial ce (more detail) 69 NA Homo sapiens

GOA IEI002566 Protein protein interactors of human gene CIRBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CIRBP (SwissProt ID= (more detail) 69 17535438 Homo sapiens

I2D MOX016477 Genes associated with Computational Drug Signature camptothecin Genes associated with Computational Drug Signature camptothecin, curated by the Drug Signature Datab (more detail) 69 25990557 Homo sapiens

DSigDB WIG001070 Genes involved in Phase II conjugation (more detail) 69 NA Homo sapiens

MSigDB FOX000292 Neighborhood of ESPL1 Neighborhood of ESPL1 extra spindle poles like 1 (S. cerevisiae) in the MORF expression compendium (more detail) 56 NA Homo sapiens

MSigDB FEX001442 Leukemia Cao06 56genes Table 2 List of differentially expressed genes of NB4 cells (more detail) 56 16705456 Homo sapiens

GeneSigDB IEI004068 Protein protein interactors of human gene EIF5A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF5A (SwissProt ID= (more detail) 71 17535438 Homo sapiens

I2D TAX025424 GO:0046068 biological process cGMP metabolic process The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate. (more detail) 27 NA Homo sapiens

GOA TAX024862 GO:0044818 biological process mitotic G2/M transition checkpoint A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part (more detail) 27 NA Homo sapiens

GOA TAX014836 GO:0003887 molecular function DNA directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synth (more detail) 27 NA Homo sapiens

GOA WEX000034 Glutamine Metabolism The genes related to glutamine metabolism (metabolism) in tumor, immune, stroma using next-generatio (more detail) 27 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas MEX002246 Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 27 25990557 Homo sapiens

DSigDB WAG000289 Elongation arrest and recovery (more detail) 27 NA Homo sapiens

Reactome TAX001092 Genes annotated by the GO term GO:0008026. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the unwinding of a DNA or RNA helix. (more detail) 27 NA Homo sapiens

MSigDB MOX007314 Genes associated with Computational Drug Signature bisindolylmaleimide i Genes associated with Computational Drug Signature bisindolylmaleimide i, curated by the Drug Signat (more detail) 27 25990557 Homo sapiens

DSigDB WAG001156 mRNA Capping (more detail) 27 NA Homo sapiens

Reactome TAX000021 Genes annotated by the GO term GO:0009310. The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. (more detail) 27 NA Homo sapiens

MSigDB MEX001616 Genes associated with Kinase Inhibitor AGN PC 087NKJ Genes associated with Kinase Inhibitor AGN-PC-087NKJ, curated by the Drug Signature Database (DSigDB (more detail) 27 25990557 Homo sapiens

DSigDB WAG000913 Pausing and recovery of HIV 1 elongation (more detail) 27 NA Homo sapiens

Reactome TAX016280 GO:0006363 biological process termination of RNA polymerase I transcription The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is co (more detail) 27 NA Homo sapiens

GOA TAX015877 GO:0005689 cellular component U12 type spliceosomal complex Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to exc (more detail) 27 NA Homo sapiens

GOA TAX016119 GO:0006084 biological process acetyl CoA metabolic process The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the su (more detail) 27 NA Homo sapiens

GOA WAG001337 HIV 1 elongation arrest and recovery (more detail) 27 NA Homo sapiens

Reactome MEX001642 Genes associated with Kinase Inhibitor AGN PC 04T5ZK Genes associated with Kinase Inhibitor AGN-PC-04T5ZK, curated by the Drug Signature Database (DSigDB (more detail) 27 25990557 Homo sapiens

DSigDB WAG001536 Pausing and recovery of elongation (more detail) 27 NA Homo sapiens

Reactome WIG000830 Genes involved in Extension of Telomeres (more detail) 27 NA Homo sapiens

MSigDB IEI003285 Protein protein interactors of human gene DAB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DAB2 (SwissProt ID=P (more detail) 75 17535438 Homo sapiens

I2D IEI014154 Protein protein interactors of human gene TRA2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRA2A (SwissProt ID= (more detail) 75 17535438 Homo sapiens

I2D IEI003651 Protein protein interactors of human gene DNAJB11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJB11 (SwissProt I (more detail) 75 17535438 Homo sapiens

I2D MOX016136 Genes associated with Computational Drug Signature cytosine Genes associated with Computational Drug Signature cytosine, curated by the Drug Signature Database (more detail) 75 25990557 Homo sapiens

DSigDB IEI006761 Protein protein interactors of human gene KDM4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM4A (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D IEI000246 Protein protein interactors of human gene ADAR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADAR (SwissProt ID=P (more detail) 49 17535438 Homo sapiens

I2D IEI010147 Protein protein interactors of human gene PMS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PMS1 (SwissProt ID=P (more detail) 49 17535438 Homo sapiens

I2D IEI001423 Protein protein interactors of human gene BRCC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRCC3 (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D WIG001647 RAR Alpha/PML Fusion During APL RAR-Alpha/PML Fusion During APL (more detail) 49 NA Homo sapiens

Protein Lounge WIG001443 Ceramide Pathway Ceramide Pathway (more detail) 49 NA Homo sapiens

Protein Lounge WEX000055 Lipid Metabolism The genes related to lipid metabolism (metabolism) in tumor, immune, stroma using next-generation se (more detail) 77 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas MOX001209 Genes associated with Computational Drug Signature protoporphyrin IX Genes associated with Computational Drug Signature protoporphyrin IX, curated by the Drug Signature (more detail) 58 25990557 Homo sapiens

DSigDB TAX000441 Genes annotated by the GO term GO:0009117. The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono , di or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates). (more detail) 39 NA Homo sapiens

MSigDB WIG001584 NF KappaB Activation by EBV NF-KappaB Activation by EBV (more detail) 39 NA Homo sapiens

Protein Lounge WIG000397 p38 MAPK Signaling Pathway p38 MAPKs are members of the MAPK family that are activated by a variety of environmental stresses a (more detail) 39 NA Homo sapiens

MSigDB IEI006148 Protein protein interactors of human gene ID3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ID3 (SwissProt ID=Q0 (more detail) 44 17535438 Homo sapiens

I2D TAX025739 GO:0046782 biological process regulation of viral transcription Any process that modulates the frequency, rate or extent of the transcription of the viral genome. (more detail) 44 NA Homo sapiens

GOA TAX000617 Genes annotated by the GO term GO:0051052. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. (more detail) 44 NA Homo sapiens

MSigDB IEI006380 Protein protein interactors of human gene IMPDH2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IMPDH2 (SwissProt ID (more detail) 60 17535438 Homo sapiens

I2D IEI003582 Protein protein interactors of human gene DLD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLD (SwissProt ID=P0 (more detail) 60 17535438 Homo sapiens

I2D TAX027896 GO:0060420 biological process regulation of heart growth Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size (more detail) 60 NA Homo sapiens

GOA IEI004754 Protein protein interactors of human gene FGFR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FGFR1 (SwissProt ID= (more detail) 60 17535438 Homo sapiens

I2D IEI002828 Protein protein interactors of human gene COMMD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD1 (SwissProt ID (more detail) 51 17535438 Homo sapiens

I2D IEI015489 Protein protein interactors of human gene ZNF326 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF326 (SwissProt ID (more detail) 51 17535438 Homo sapiens

I2D IEI005147 Protein protein interactors of human gene GEMIN5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GEMIN5 (SwissProt ID (more detail) 51 17535438 Homo sapiens

I2D TAX020385 GO:0030218 biological process erythrocyte differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. (more detail) 51 NA Homo sapiens

GOA IEI013335 Protein protein interactors of human gene TADA3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TADA3 (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D TAX013301 GO:0000186 biological process activation of MAPKK activity The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK). (more detail) 51 NA Homo sapiens

GOA MOX016962 Genes associated with Computational Drug Signature emodin Genes associated with Computational Drug Signature emodin, curated by the Drug Signature Database (D (more detail) 62 25990557 Homo sapiens

DSigDB MOX013816 Genes associated with Computational Drug Signature myricetin Genes associated with Computational Drug Signature myricetin, curated by the Drug Signature Database (more detail) 62 25990557 Homo sapiens

DSigDB IEI014654 Protein protein interactors of human gene UFD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UFD1 (SwissProt ID=Q (more detail) 62 17535438 Homo sapiens

I2D IEI004256 Protein protein interactors of human gene ERCC8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERCC8 (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D IEI002239 Protein protein interactors of human gene CDK11A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK11A (SwissProt ID (more detail) 36 17535438 Homo sapiens

I2D IEI009854 Protein protein interactors of human gene PHF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHF8 (SwissProt ID=Q (more detail) 36 17535438 Homo sapiens

I2D IEI010949 Protein protein interactors of human gene RAD9A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD9A (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D IEI015141 Protein protein interactors of human gene YAF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YAF2 (SwissProt ID=Q (more detail) 36 17535438 Homo sapiens

I2D TAX015090 GO:0004364 molecular function glutathione transferase activity Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromati (more detail) 36 NA Homo sapiens

GOA TAX013644 GO:0001221 molecular function transcription cofactor binding Interacting selectively and non-covalently with a transcription cofactor, any protein involved in re (more detail) 36 NA Homo sapiens

GOA PEX001568 Homeobox: Homeobox domain (more detail) 36 NA Homo sapiens

Pfam IEI014243 Protein protein interactors of human gene TRIM39 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM39 (SwissProt ID (more detail) 64 17535438 Homo sapiens

I2D WIG002033 DNA damage response DNA damage response (more detail) 64 NA Homo sapiens

WikiPathway TAX020542 GO:0030515 molecular function snoRNA binding Interacting selectively and non-covalently with small nucleolar RNA. (more detail) 30 NA Homo sapiens

GOA IEI004573 Protein protein interactors of human gene FANCM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FANCM (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D WIG000018 ATM pathway (more detail) 30 NA Homo sapiens

MSigDB MEX001287 Genes associated with Kinase Inhibitor BI 2536 Genes associated with Kinase Inhibitor BI 2536, curated by the Drug Signature Database (DSigDB). (more detail) 30 25990557 Homo sapiens

DSigDB WIG001028 Genes involved in NOD1/2 Signaling Pathway (more detail) 30 NA Homo sapiens

MSigDB FEX001891 Lung Kobayashi06 42genes Table 2. E2F target genes down-regulated by CL-387 785 at 24 hours (more detail) 30 17145885 Homo sapiens

GeneSigDB WIG001133 Genes involved in Regulation of beta cell development (more detail) 30 NA Homo sapiens

MSigDB WIG000465 Alanine, aspartate and glutamate metabolism (more detail) 30 NA Homo sapiens

MSigDB WAG000805 Selenoamino acid metabolism (more detail) 30 NA Homo sapiens

KEGG WAG000998 Arginine and proline metabolism (more detail) 30 NA Homo sapiens

KEGG WIG000157 Retinoic acid receptors mediated signaling (more detail) 30 NA Homo sapiens

MSigDB WIG000672 Genes involved in Activation of the pre replicative complex (more detail) 30 NA Homo sapiens

MSigDB WIG000968 Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases (more detail) 30 NA Homo sapiens

MSigDB WAG000820 Glioma Gliomas are the most common of the primary brain tumors and account for more than 40% of all central (more detail) 53 NA Homo sapiens

KEGG TAX000140 Genes annotated by the GO term GO:0051186. The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. (more detail) 53 NA Homo sapiens

MSigDB WIG001613 PACAP Signaling PACAP Signaling (more detail) 53 NA Homo sapiens

Protein Lounge WIG000111 Signaling events mediated by Stem cell factor receptor (c Kit) (more detail) 53 NA Homo sapiens

MSigDB FEX001612 Leukemia Carlucci09 57genes Table 1 Genes spotted on the chip. The Cy3/Cy5 ratio is reported as mean +/- SD of five patients spo (more detail) 53 19278812 Homo sapiens

GeneSigDB IEI011766 Protein protein interactors of human gene SAE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SAE1 (SwissProt ID=Q (more detail) 53 17535438 Homo sapiens

I2D TAX021079 GO:0031624 molecular function ubiquitin conjugating enzyme binding Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 protei (more detail) 33 NA Homo sapiens

GOA IEI013339 Protein protein interactors of human gene TAF12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF12 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI002468 Protein protein interactors of human gene CHD8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD8 (SwissProt ID=Q (more detail) 33 17535438 Homo sapiens

I2D TAX000313 Genes annotated by the GO term GO:0042157. The chemical reactions and pathways involving any conjugated, water soluble protein in which the nonprotein moiety consists of a lipid or lipids. (more detail) 33 NA Homo sapiens

MSigDB WAG001625 Basal transcription factors (more detail) 33 NA Homo sapiens

KEGG WIG001699 TNF Induced Apoptosis Implicating Sphingolipids TNF-Induced Apoptosis Implicating Sphingolipids (more detail) 33 NA Homo sapiens

Protein Lounge MOX003973 Genes associated with Computational Drug Signature DEHP Genes associated with Computational Drug Signature DEHP, curated by the Drug Signature Database (DSi (more detail) 46 25990557 Homo sapiens

DSigDB TAX000771 Genes annotated by the GO term GO:0031098. A series of molecular signals in which a stress activated protein kinase (SAPK) cascade relays one or more of the signals. (more detail) 46 NA Homo sapiens

MSigDB IEI005460 Protein protein interactors of human gene GPS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GPS1 (SwissProt ID=Q (more detail) 46 17535438 Homo sapiens

I2D IEI003419 Protein protein interactors of human gene DDX39A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX39A (SwissProt ID (more detail) 46 17535438 Homo sapiens

I2D IEI008857 Protein protein interactors of human gene NKRF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NKRF (SwissProt ID=O (more detail) 46 17535438 Homo sapiens

I2D IEI002038 Protein protein interactors of human gene CCNC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNC (SwissProt ID=P (more detail) 66 17535438 Homo sapiens

I2D IEI013042 Protein protein interactors of human gene ST13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ST13 (SwissProt ID=P (more detail) 66 17535438 Homo sapiens

I2D IEI014246 Protein protein interactors of human gene TRIM41 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM41 (SwissProt ID (more detail) 68 17535438 Homo sapiens

I2D IEI007820 Protein protein interactors of human gene MDH2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MDH2 (SwissProt ID=P (more detail) 68 17535438 Homo sapiens

I2D IEI014796 Protein protein interactors of human gene USP5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP5 (SwissProt ID=P (more detail) 68 17535438 Homo sapiens

I2D IEI010711 Protein protein interactors of human gene PTGS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTGS2 (SwissProt ID= (more detail) 41 17535438 Homo sapiens

I2D TAX028864 GO:0070316 biological process regulation of G0 to G1 transition A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state (more detail) 41 NA Homo sapiens

GOA IEI007155 Protein protein interactors of human gene LAS1L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LAS1L (SwissProt ID= (more detail) 41 17535438 Homo sapiens

I2D WIG000916 Genes involved in Interleukin 2 signaling (more detail) 41 NA Homo sapiens

MSigDB MAX000014 Proteins interacting with AIRE [GeneID=326], based on massspectroscopy analysis of co immunoprecipitates in 293T cells (embryonic kidney). Aire induces the expression of a battery of peripheral-tissue self-antigens (PTAs) in thymic stromal (more detail) 41 NA Homo sapiens

MSigDB WIG001516 G2 M Phase Transition G2-M Phase Transition (more detail) 41 NA Homo sapiens

Protein Lounge MOX015117 Genes associated with Computational Drug Signature SMR000103217 Genes associated with Computational Drug Signature SMR000103217, curated by the Drug Signature Datab (more detail) 41 25990557 Homo sapiens

DSigDB IEI001211 Protein protein interactors of human gene BAG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BAG1 (SwissProt ID=Q (more detail) 70 17535438 Homo sapiens

I2D WIG001413 VEGF Signaling Pathway Model endothelial cell displaying genes of the VEGF signalling pathway and the sites at which bevaci (more detail) 55 NA Homo sapiens

PharmGKB IEI008810 Protein protein interactors of human gene NFYC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFYC (SwissProt ID=Q (more detail) 55 17535438 Homo sapiens

I2D IEI002308 Protein protein interactors of human gene CEBPE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CEBPE (SwissProt ID= (more detail) 55 17535438 Homo sapiens

I2D MOX004192 Genes associated with Computational Drug Signature DL Homocysteine Genes associated with Computational Drug Signature DL-Homocysteine, curated by the Drug Signature Da (more detail) 55 25990557 Homo sapiens

DSigDB TAX000255 Genes annotated by the GO term GO:0030097. The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. (more detail) 72 NA Homo sapiens

MSigDB MOX002746 Genes associated with Computational Drug Signature rottlerin Genes associated with Computational Drug Signature rottlerin, curated by the Drug Signature Database (more detail) 74 25990557 Homo sapiens

DSigDB MEX003189 Genes associated with Perturbagen Signature felodipine Genes associated with Perturbagen Signature felodipine, curated by the Drug Signature Database (DSig (more detail) 76 25990557 Homo sapiens

DSigDB IEI014767 Protein protein interactors of human gene USP22 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP22 (SwissProt ID= (more detail) 48 17535438 Homo sapiens

I2D IEI000390 Protein protein interactors of human gene AHR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AHR (SwissProt ID=P3 (more detail) 48 17535438 Homo sapiens

I2D IEI006487 Protein protein interactors of human gene IRF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IRF4 (SwissProt ID=Q (more detail) 57 17535438 Homo sapiens

I2D TAX028961 GO:0070491 molecular function repressing transcription factor binding Interacting selectively and non-covalently with a transcription repressor, any protein whose activit (more detail) 57 NA Homo sapiens

GOA IEI004913 Protein protein interactors of human gene FRS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FRS2 (SwissProt ID=Q (more detail) 57 17535438 Homo sapiens

I2D MAX002713 Cellular genes up regulated in forskin fibroblasts by expression of CMV EI86 protein off an adenovirus vector. We have previously reported that the immediate early (IE)-86 protein of human cytomegalovirus (HCMV) (more detail) 57 NA Homo sapiens

MSigDB MOX002602 Genes associated with Computational Drug Signature Alvocidib Genes associated with Computational Drug Signature Alvocidib, curated by the Drug Signature Database (more detail) 57 25990557 Homo sapiens

DSigDB WIG000168 SHP2 signaling (more detail) 57 NA Homo sapiens

MSigDB IEI010193 Protein protein interactors of human gene POLD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLD3 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D TAX028678 GO:0070001 molecular function aspartic type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water (more detail) 26 NA Homo sapiens

GOA TAX017481 GO:0009065 biological process glutamine family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine famil (more detail) 26 NA Homo sapiens

GOA IEI007838 Protein protein interactors of human gene MED11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED11 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D TAX020369 GO:0030201 biological process heparan sulfate proteoglycan metabolic process The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any membe (more detail) 26 NA Homo sapiens

GOA TAX020848 GO:0031167 biological process rRNA methylation The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule. (more detail) 26 NA Homo sapiens

GOA TAX020950 GO:0031365 biological process N terminal protein amino acid modification The alteration of the N-terminal amino acid residue in a protein. (more detail) 26 NA Homo sapiens

GOA TAX023287 GO:0036151 biological process phosphatidylcholine acyl chain remodeling Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation r (more detail) 26 NA Homo sapiens

GOA TAX021932 GO:0033014 biological process tetrapyrrole biosynthetic process The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments cont (more detail) 26 NA Homo sapiens

GOA TAX015335 GO:0004709 molecular function MAP kinase kinase kinase activity Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can b (more detail) 26 NA Homo sapiens

GOA TAX028509 GO:0061620 biological process glycolytic process through glucose 6 phosphate The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occu (more detail) 26 NA Homo sapiens

GOA TAX019484 GO:0018195 biological process peptidyl arginine modification The modification of peptidyl-arginine. (more detail) 26 NA Homo sapiens

GOA TAX029183 GO:0070911 biological process global genome nucleotide excision repair The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands (more detail) 26 NA Homo sapiens

GOA TAX028507 GO:0061615 biological process glycolytic process through fructose 6 phosphate The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, oc (more detail) 26 NA Homo sapiens

GOA WAG001070 BARD1 signaling events (more detail) 26 NA Homo sapiens

NCI-Nature Curated WAG000526 Tat mediated HIV 1 elongation arrest and recovery (more detail) 26 NA Homo sapiens

Reactome WIG000529 Glycosaminoglycan biosynthesis heparan sulfate (more detail) 26 NA Homo sapiens

MSigDB TAX016289 GO:0006379 biological process mRNA cleavage Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated mann (more detail) 26 NA Homo sapiens

GOA WIG001550 Huntingtin Comparative Pathway Huntingtin Comparative Pathway (more detail) 26 NA Homo sapiens

Protein Lounge MEX002158 Genes associated with Kinase Inhibitor Enzastaurin Genes associated with Kinase Inhibitor Enzastaurin, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens

DSigDB WIG000162 RXR and RAR heterodimerization with other nuclear receptor (more detail) 26 NA Homo sapiens

MSigDB TAX000312 Genes annotated by the GO term GO:0042158. The chemical reactions and pathways resulting in the formation of any conjugated, water soluble protein in which the nonprotein moiety consists of a lipid or lipids. (more detail) 26 NA Homo sapiens

MSigDB MEX002214 Genes associated with Kinase Inhibitor 3ztx Genes associated with Kinase Inhibitor 3ztx, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens

DSigDB TAX016384 GO:0006515 biological process protein quality control for misfolded or incompletely synthesized proteins The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins. (more detail) 26 NA Homo sapiens

GOA WAG000109 Pausing and recovery of Tat mediated HIV 1 elongation (more detail) 26 NA Homo sapiens

Reactome WIG000580 O Glycan biosynthesis O-glycans are a class of glycans that modify serine or threonine residues of proteins. Biosynthesis (more detail) 26 NA Homo sapiens

MSigDB WIG000542 Homologous recombination Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs (more detail) 26 NA Homo sapiens

MSigDB MEX002195 Genes associated with Kinase Inhibitor BX 912 Genes associated with Kinase Inhibitor BX-912, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens

DSigDB MEX002192 Genes associated with Kinase Inhibitor ILORASERTIB Genes associated with Kinase Inhibitor ILORASERTIB, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens

DSigDB IEI008472 Protein protein interactors of human gene MYO1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYO1B (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D IEI014710 Protein protein interactors of human gene UPF3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UPF3B (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D TAX028865 GO:0070317 biological process negative regulation of G0 to G1 transition A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the (more detail) 38 NA Homo sapiens

GOA IEI014153 Protein protein interactors of human gene TPX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TPX2 (SwissProt ID=Q (more detail) 38 17535438 Homo sapiens

I2D FOX000231 Neighborhood of UBE2I Neighborhood of UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) in the GNF2 expression (more detail) 38 NA Homo sapiens

MSigDB TAX020780 GO:0031057 biological process negative regulation of histone modification Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteratio (more detail) 38 NA Homo sapiens

GOA IEI003105 Protein protein interactors of human gene CTCF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTCF (SwissProt ID=P (more detail) 59 17535438 Homo sapiens

I2D IEI015310 Protein protein interactors of human gene ZFP36 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZFP36 (SwissProt ID= (more detail) 59 17535438 Homo sapiens

I2D IEI012658 Protein protein interactors of human gene SNAI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNAI1 (SwissProt ID= (more detail) 59 17535438 Homo sapiens

I2D IEI001008 Protein protein interactors of human gene ATAD3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATAD3B (SwissProt ID (more detail) 43 17535438 Homo sapiens

I2D IEI010226 Protein protein interactors of human gene POLR2J from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2J (SwissProt ID (more detail) 43 17535438 Homo sapiens

I2D TAX030498 GO:0090329 biological process regulation of DNA dependent DNA replication Any process that modulates the rate, frequency, or extent of DNA-dependent DNA replication, the proc (more detail) 43 NA Homo sapiens

GOA TAX027539 GO:0055025 biological process positive regulation of cardiac muscle tissue development Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle t (more detail) 43 NA Homo sapiens

GOA IEI011184 Protein protein interactors of human gene REST from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene REST (SwissProt ID=Q (more detail) 43 17535438 Homo sapiens

I2D IEI012649 Protein protein interactors of human gene SMU1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMU1 (SwissProt ID=Q (more detail) 50 17535438 Homo sapiens

I2D TAX026829 GO:0051146 biological process striated muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a striated mus (more detail) 50 NA Homo sapiens

GOA WIG001697 TNF Signaling TNF Signaling (more detail) 50 NA Homo sapiens

Protein Lounge FOX000041 Neighborhood of HBP1 Neighborhood of HBP1 HMG-box transcription factor 1 in the GCM expression compendium (more detail) 61 NA Homo sapiens

MSigDB FOX000321 Neighborhood of JUND Neighborhood of JUND jun D proto-oncogene in the MORF expression compendium (more detail) 61 NA Homo sapiens

MSigDB TAX027187 GO:0051785 biological process positive regulation of nuclear division Any process that activates or increases the frequency, rate or extent of nuclear division, the parti (more detail) 63 NA Homo sapiens

GOA IEI012466 Protein protein interactors of human gene SLC3A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC3A2 (SwissProt ID (more detail) 63 17535438 Homo sapiens

I2D TAX013785 GO:0001708 biological process cell fate specification The process involved in the specification of cell identity. Once specification has taken place, a ce (more detail) 63 NA Homo sapiens

GOA MOX000328 Genes associated with Computational Drug Signature Dibenziodolium Genes associated with Computational Drug Signature Dibenziodolium, curated by the Drug Signature Dat (more detail) 63 25990557 Homo sapiens

DSigDB MOX015829 Genes associated with Computational Drug Signature Velcade(Bortezomib) Genes associated with Computational Drug Signature Velcade(Bortezomib), curated by the Drug Signatur (more detail) 35 25990557 Homo sapiens

DSigDB IEI008474 Protein protein interactors of human gene MYO1D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYO1D (SwissProt ID= (more detail) 35 17535438 Homo sapiens

I2D IEI002309 Protein protein interactors of human gene CEBPG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CEBPG (SwissProt ID= (more detail) 35 17535438 Homo sapiens

I2D IEI011726 Protein protein interactors of human gene RXRG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RXRG (SwissProt ID=P (more detail) 35 17535438 Homo sapiens

I2D WIG000079 HIF 1 alpha transcription factor network (more detail) 65 NA Homo sapiens

MSigDB MOX016580 Genes associated with Computational Drug Signature colchicine Genes associated with Computational Drug Signature colchicine, curated by the Drug Signature Databas (more detail) 65 25990557 Homo sapiens

DSigDB MOX002330 Genes associated with Computational Drug Signature h 89 Genes associated with Computational Drug Signature h-89, curated by the Drug Signature Database (DSi (more detail) 65 25990557 Homo sapiens

DSigDB WIG000025 BCR signaling pathway (more detail) 65 NA Homo sapiens

MSigDB IEI009809 Protein protein interactors of human gene PGK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PGK1 (SwissProt ID=P (more detail) 65 17535438 Homo sapiens

I2D IEI012369 Protein protein interactors of human gene SLC25A4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC25A4 (SwissProt I (more detail) 52 17535438 Homo sapiens

I2D TAX021388 GO:0032210 biological process regulation of telomere maintenance via telomerase Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by tel (more detail) 52 NA Homo sapiens

GOA IEI014549 Protein protein interactors of human gene UBA52 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBA52 (SwissProt ID= (more detail) 67 17535438 Homo sapiens

I2D TAX017382 GO:0008630 biological process intrinsic apoptotic signaling pathway in response to DNA damage A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic (more detail) 67 NA Homo sapiens

GOA FOX000264 Neighborhood of CDC16 Neighborhood of CDC16 CDC16 cell division cycle 16 homolog (S. cerevisiae) in the MORF expression c (more detail) 67 NA Homo sapiens

MSigDB WIG000464 Adipocytokine signaling pathway Increased adipocyte volume and number are positively correlated with leptin production, and negative (more detail) 67 NA Homo sapiens

MSigDB WAG000613 Adipocytokine signaling pathway Increased adipocyte volume and number are positively correlated with leptin production, and negative (more detail) 67 NA Homo sapiens

KEGG FEX002477 Ovarian Maloney07 84genes Table 1a. Genes that show decreased expression at the mRNA level in A2780 human ovarian cancer cells (more detail) 67 17409432 Homo sapiens

GeneSigDB FAX003052 GSEA Hallmark Lung Cancer Tissue Explants (Extracellular Vesicles) E2F Targets Top 3 pathways enriched in lung cancer tissue extract extracellular vesicle particles compared to ma (more detail) 45 32795414 Homo sapiens

Cell IEI011138 Protein protein interactors of human gene RCOR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RCOR1 (SwissProt ID= (more detail) 45 17535438 Homo sapiens

I2D IEI004793 Protein protein interactors of human gene FKBP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FKBP3 (SwissProt ID= (more detail) 45 17535438 Homo sapiens

I2D IEI011788 Protein protein interactors of human gene SAP30BP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SAP30BP (SwissProt I (more detail) 45 17535438 Homo sapiens

I2D IEI004570 Protein protein interactors of human gene FANCG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FANCG (SwissProt ID= (more detail) 45 17535438 Homo sapiens

I2D IEI007863 Protein protein interactors of human gene MED7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED7 (SwissProt ID=O (more detail) 45 17535438 Homo sapiens

I2D IEI005602 Protein protein interactors of human gene GTPBP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTPBP4 (SwissProt ID (more detail) 45 17535438 Homo sapiens

I2D WAG000379 Non small cell lung cancer Lung cancer is a leading cause of cancer death among men and women in industrialized countries. Non- (more detail) 45 NA Homo sapiens

KEGG MOX014986 Genes associated with Computational Drug Signature SB 202190 Genes associated with Computational Drug Signature SB 202190, curated by the Drug Signature Database (more detail) 45 25990557 Homo sapiens

DSigDB WIG000217 Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. na (more detail) 45 NA Homo sapiens

MSigDB WIG001631 PKR Pathway PKR Pathway (more detail) 45 NA Homo sapiens

Protein Lounge IEI004055 Protein protein interactors of human gene EIF4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF4B (SwissProt ID= (more detail) 69 17535438 Homo sapiens

I2D FOX000422 Neighborhood of UNG Neighborhood of UNG uracil-DNA glycosylase in the MORF expression compendium (more detail) 69 NA Homo sapiens

MSigDB WIG000582 Pancreatic cancer Normal duct epithelium progresses to infiltrating cancer through a series of histologically defined (more detail) 69 NA Homo sapiens

MSigDB TAX024813 GO:0044665 cellular component MLL1/2 complex A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protei (more detail) 29 NA Homo sapiens

GOA IEI000336 Protein protein interactors of human gene AFF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AFF1 (SwissProt ID=P (more detail) 29 17535438 Homo sapiens

I2D TAX016070 GO:0006007 biological process glucose catabolic process The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexo (more detail) 29 NA Homo sapiens

GOA IEI009026 Protein protein interactors of human gene NR2C1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR2C1 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI007575 Protein protein interactors of human gene MAFK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAFK (SwissProt ID=O (more detail) 29 17535438 Homo sapiens

I2D IEI005834 Protein protein interactors of human gene HIC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HIC1 (SwissProt ID=Q (more detail) 29 17535438 Homo sapiens

I2D IEI005801 Protein protein interactors of human gene HERC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HERC5 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D TAX029397 GO:0071339 cellular component MLL1 complex A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransfe (more detail) 29 NA Homo sapiens

GOA PEX000431 DSPc: Dual specificity phosphatase, catalytic domain Ser/Thr and Tyr protein phosphatases. The enzymes tertiary fold is highly similar to that of tyrosin (more detail) 29 NA Homo sapiens

Pfam WIG001933 One Carbon Metabolism One Carbon Metabolism (more detail) 29 NA Homo sapiens

WikiPathway WIG000998 Genes involved in mRNA Capping (more detail) 29 NA Homo sapiens

MSigDB WIG000791 Genes involved in Degradation of the extracellular matrix (more detail) 29 NA Homo sapiens

MSigDB FOX000558 Genes in the cancer module 229 (more detail) 29 NA Homo sapiens

MSigDB MOX007315 Genes associated with Computational Drug Signature bisindolylmaleimide iv Genes associated with Computational Drug Signature bisindolylmaleimide iv, curated by the Drug Signa (more detail) 29 25990557 Homo sapiens

DSigDB WIG000848 Genes involved in Formation of transcription coupled NER (TC NER) repair complex (more detail) 29 NA Homo sapiens

MSigDB WIG000846 Genes involved in Formation of the HIV 1 Early Elongation Complex (more detail) 29 NA Homo sapiens

MSigDB IEI009609 Protein protein interactors of human gene PCK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCK1 (SwissProt ID=P (more detail) 71 17535438 Homo sapiens

I2D IEI001274 Protein protein interactors of human gene BCL10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCL10 (SwissProt ID= (more detail) 71 17535438 Homo sapiens

I2D MOX012502 Genes associated with Computational Drug Signature ellipticine Genes associated with Computational Drug Signature ellipticine, curated by the Drug Signature Databa (more detail) 71 25990557 Homo sapiens

DSigDB IEI013351 Protein protein interactors of human gene TAF5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF5 (SwissProt ID=Q (more detail) 32 17535438 Homo sapiens

I2D IEI002675 Protein protein interactors of human gene CLSPN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLSPN (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D IEI015098 Protein protein interactors of human gene XAB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XAB2 (SwissProt ID=Q (more detail) 32 17535438 Homo sapiens

I2D IEI007756 Protein protein interactors of human gene MBD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MBD2 (SwissProt ID=Q (more detail) 32 17535438 Homo sapiens

I2D IEI010932 Protein protein interactors of human gene RAD17 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD17 (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D IEI003894 Protein protein interactors of human gene E2F6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene E2F6 (SwissProt ID=O (more detail) 32 17535438 Homo sapiens

I2D TAX030168 GO:0080008 cellular component Cul4 RING E3 ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the (more detail) 32 NA Homo sapiens

GOA WAG000818 Riboflavin metabolism (more detail) 32 NA Homo sapiens

KEGG TAX014417 GO:0002753 biological process cytoplasmic pattern recognition receptor signaling pathway Any series of molecular signals generated as a consequence of a cytoplasmic pattern recognition rece (more detail) 32 NA Homo sapiens

GOA WIG001421 Thiopurine Pathway, Pharmacokinetics/Pharmacodynamics Thiopurine Pathway, Pharmacokinetics/Pharmacodynamics (more detail) 32 NA Homo sapiens

PharmGKB WAG001616 Colorectal cancer Colorectal cancer (CRC) is the second largest cause of cancer-related deaths in Western countries. C (more detail) 73 NA Homo sapiens

KEGG IEI003650 Protein protein interactors of human gene DNAJB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJB1 (SwissProt ID (more detail) 73 17535438 Homo sapiens

I2D IEI010755 Protein protein interactors of human gene PTPRJ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTPRJ (SwissProt ID= (more detail) 73 17535438 Homo sapiens

I2D IEI005594 Protein protein interactors of human gene GTF3C3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF3C3 (SwissProt ID (more detail) 40 17535438 Homo sapiens

I2D TAX020469 GO:0030331 molecular function estrogen receptor binding Interacting selectively and non-covalently with an estrogen receptor. (more detail) 40 NA Homo sapiens

GOA IEI010163 Protein protein interactors of human gene PNO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PNO1 (SwissProt ID=Q (more detail) 40 17535438 Homo sapiens

I2D IEI009024 Protein protein interactors of human gene NR1I2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR1I2 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D TAX022711 GO:0035051 biological process cardiocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or func (more detail) 40 NA Homo sapiens

GOA WIG000571 Non small cell lung cancer Non-small-cell lung cancer (NSCLC) accounts for approximately 80% of lung cancer and represents a he (more detail) 54 NA Homo sapiens

MSigDB WIG000385 NFAT and Hypertrophy of the heart (Transcription in the broken heart) Hypertrophy associated with both hypertension and obstruction to ventricular outflow leads to pathol (more detail) 54 NA Homo sapiens

MSigDB FEX001746 Liver Semeus08 65genes Table 1. Gene expression profiling in HepG2 cells incubated with or without etoposide (e 50 microme (more detail) 54 18366759 Homo sapiens

GeneSigDB TAX025540 GO:0046364 biological process monosaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcoho (more detail) 54 NA Homo sapiens

GOA TAX033191 GO:1903902 biological process positive regulation of viral life cycle Any process that activates or increases the frequency, rate or extent of viral life cycle. (more detail) 56 NA Homo sapiens

GOA IEI011449 Protein protein interactors of human gene RNF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF8 (SwissProt ID=O (more detail) 56 17535438 Homo sapiens

I2D IEI012796 Protein protein interactors of human gene SP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SP3 (SwissProt ID=Q0 (more detail) 47 17535438 Homo sapiens

I2D TAX025194 GO:0045646 biological process regulation of erythrocyte differentiation Any process that modulates the frequency, rate or extent of erythrocyte differentiation. (more detail) 47 NA Homo sapiens

GOA WIG002003 Glycolysis and Gluconeogenesis Glycolysis and Gluconeogenesis (more detail) 47 NA Homo sapiens

WikiPathway MOX000217 Genes associated with Computational Drug Signature Ursolic acid Genes associated with Computational Drug Signature Ursolic acid, curated by the Drug Signature Datab (more detail) 47 25990557 Homo sapiens

DSigDB TAX000065 Genes annotated by the GO term GO:0016051. The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. (more detail) 47 NA Homo sapiens

MSigDB WIG001560 IL 3 Pathway IL-3 Pathway (more detail) 47 NA Homo sapiens

Protein Lounge WAG001223 Tryptophan metabolism (more detail) 47 NA Homo sapiens

KEGG WIG000572 Notch signaling pathway The Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essent (more detail) 47 NA Homo sapiens

MSigDB IEI003461 Protein protein interactors of human gene DEK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DEK (SwissProt ID=P3 (more detail) 58 17535438 Homo sapiens

I2D IEI015339 Protein protein interactors of human gene ZHX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZHX1 (SwissProt ID=Q (more detail) 58 17535438 Homo sapiens

I2D MOX004347 Genes associated with Computational Drug Signature methylene blue Genes associated with Computational Drug Signature methylene blue, curated by the Drug Signature Dat (more detail) 58 25990557 Homo sapiens

DSigDB MOX002869 Genes associated with Computational Drug Signature Tyrphostin B42 Genes associated with Computational Drug Signature Tyrphostin B42, curated by the Drug Signature Dat (more detail) 58 25990557 Homo sapiens

DSigDB TAX020569 GO:0030574 biological process collagen catabolic process The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extrac (more detail) 37 NA Homo sapiens

GOA IEI015265 Protein protein interactors of human gene ZCCHC8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZCCHC8 (SwissProt ID (more detail) 37 17535438 Homo sapiens

I2D IEI004780 Protein protein interactors of human gene FIP1L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FIP1L1 (SwissProt ID (more detail) 37 17535438 Homo sapiens

I2D IEI006326 Protein protein interactors of human gene IL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL2 (SwissProt ID=P6 (more detail) 37 17535438 Homo sapiens

I2D WIG001289 Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (more detail) 37 NA Homo sapiens

MSigDB WIG000071 GMCSF mediated signaling events (more detail) 37 NA Homo sapiens

MSigDB FAX000479 Genes with promoter regions [ 2kb,2kb] around transcription start site containing motif TWSGCGCGAAAAYKR. Motif does not match any known transcription factor Genes with promoter regions [-2kb,2kb] around transcription start site containing motif TWSGCGCGAAAA (more detail) 60 NA Homo sapiens

MSigDB WIG000569 NOD like receptor signaling pathway Specific families of pattern recognition receptors are responsible for detecting various pathogens a (more detail) 60 NA Homo sapiens

MSigDB TAX028854 GO:0070301 biological process cellular response to hydrogen peroxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 60 NA Homo sapiens

GOA WEX000033 Glioma The genes related to glioma (physiology & disease) in tumor using next-generation sequencer (NGS) re (more detail) 60 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI011053 Protein protein interactors of human gene RBBP6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBBP6 (SwissProt ID= (more detail) 60 17535438 Homo sapiens

I2D IEI003568 Protein protein interactors of human gene DIS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIS3 (SwissProt ID=Q (more detail) 42 17535438 Homo sapiens

I2D IEI013696 Protein protein interactors of human gene TIAM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TIAM1 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D IEI000433 Protein protein interactors of human gene AKAP8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKAP8 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D IEI015365 Protein protein interactors of human gene ZMYM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZMYM2 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D IEI013445 Protein protein interactors of human gene TBL1XR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBL1XR1 (SwissProt I (more detail) 42 17535438 Homo sapiens

I2D IEI001021 Protein protein interactors of human gene ATF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATF7 (SwissProt ID=P (more detail) 42 17535438 Homo sapiens

I2D WIG001077 Genes involved in PI3K events in ERBB2 signaling (more detail) 42 NA Homo sapiens

MSigDB WAG000666 IL6 mediated signaling events (more detail) 42 NA Homo sapiens

NCI-Nature Curated TAX025200 GO:0045652 biological process regulation of megakaryocyte differentiation Any process that modulates the frequency, rate or extent of megakaryocyte differentiation. (more detail) 49 NA Homo sapiens

GOA IEI005291 Protein protein interactors of human gene GMPS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GMPS (SwissProt ID=P (more detail) 49 17535438 Homo sapiens

I2D IEI006147 Protein protein interactors of human gene ID2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ID2 (SwissProt ID=Q0 (more detail) 49 17535438 Homo sapiens

I2D IEI010292 Protein protein interactors of human gene PPARD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPARD (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D TAX024418 GO:0043525 biological process positive regulation of neuron apoptotic process Any process that activates or increases the frequency, rate or extent of cell death of neurons by ap (more detail) 49 NA Homo sapiens

GOA MAX000796 Genes down regulated in MCF 7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4 hydroxytamoxifen, raloxifene, or ICI 182780 but not by estradiol [PubChem=44959;5035;3478439;5757]. Selective estrogen receptor modulators (SERMs) such as tamoxifen are effective in the treatment of m (more detail) 49 NA Homo sapiens

MSigDB WIG002008 Complement and Coagulation Cascades Complement and Coagulation Cascades (more detail) 49 NA Homo sapiens

WikiPathway TAX016562 GO:0006735 biological process NADH regeneration A metabolic process that generates a pool of NADH by the reduction of NAD+. (more detail) 25 NA Homo sapiens

GOA TAX017584 GO:0009190 biological process cyclic nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide (more detail) 25 NA Homo sapiens

GOA TAX017202 GO:0008327 molecular function methyl CpG binding Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide. (more detail) 25 NA Homo sapiens

GOA TAX019446 GO:0018023 biological process peptidyl lysine trimethylation The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine. (more detail) 25 NA Homo sapiens

GOA TAX027419 GO:0052652 biological process cyclic purine nucleotide metabolic process The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phospha (more detail) 25 NA Homo sapiens

GOA TAX026415 GO:0050145 molecular function nucleoside monophosphate kinase activity Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate. (more detail) 25 NA Homo sapiens

GOA TAX018149 GO:0010833 biological process telomere maintenance via telomere lengthening Any process that contributes to the maintenance of proper telomeric length and structure by affectin (more detail) 25 NA Homo sapiens

GOA TAX022825 GO:0035336 biological process long chain fatty acyl CoA metabolic process The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme (more detail) 25 NA Homo sapiens

GOA TAX019469 GO:0018126 biological process protein hydroxylation The addition of a hydroxy group to a protein amino acid. (more detail) 25 NA Homo sapiens

GOA TAX028510 GO:0061621 biological process canonical glycolysis The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokin (more detail) 25 NA Homo sapiens

GOA TAX020374 GO:0030206 biological process chondroitin sulfate biosynthetic process The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of (more detail) 25 NA Homo sapiens

GOA TAX028556 GO:0061718 biological process glucose catabolic process to pyruvate The chemical reactions and pathways resulting in the breakdown of glucose, with the production of py (more detail) 25 NA Homo sapiens

GOA TAX019342 GO:0017025 molecular function TBP class protein binding Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP) (more detail) 25 NA Homo sapiens

GOA TAX017648 GO:0009299 biological process mRNA transcription The cellular synthesis of messenger RNA (mRNA) from a DNA template. (more detail) 25 NA Homo sapiens

GOA MEX002062 Genes associated with Kinase Inhibitor Crenolanib Genes associated with Kinase Inhibitor Crenolanib, curated by the Drug Signature Database (DSigDB). (more detail) 25 25990557 Homo sapiens

DSigDB TAX000025 Genes annotated by the GO term GO:0009063. The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. (more detail) 25 NA Homo sapiens

MSigDB WIG000719 Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis (more detail) 25 NA Homo sapiens

MSigDB TAX001143 Genes annotated by the GO term GO:0003678. Catalysis of the unwinding of a DNA duplex. (more detail) 25 NA Homo sapiens

MSigDB WIG000955 Genes involved in Keratan sulfate biosynthesis (more detail) 25 NA Homo sapiens

MSigDB TAX016354 GO:0006471 biological process protein ADP ribosylation The transfer, from NAD, of ADP-ribose to protein amino acids. (more detail) 25 NA Homo sapiens

GOA WIG000534 Glycosphingolipid biosynthesis lacto and neolacto series (more detail) 25 NA Homo sapiens

MSigDB TAX013310 GO:0000217 molecular function DNA secondary structure binding Interacting selectively and non-covalently with DNA containing secondary structure elements such as (more detail) 25 NA Homo sapiens

GOA MEX001658 Genes associated with Kinase Inhibitor GW768505A Genes associated with Kinase Inhibitor GW768505A, curated by the Drug Signature Database (DSigDB). (more detail) 25 25990557 Homo sapiens

DSigDB WAG000313 RNA Pol II CTD phosphorylation and interaction with CE (more detail) 25 NA Homo sapiens

Reactome TAX001356 Genes annotated by the GO term GO:0004540. Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. (more detail) 25 NA Homo sapiens

MSigDB TAX015033 GO:0004190 molecular function aspartic type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism i (more detail) 25 NA Homo sapiens

GOA TAX016249 GO:0006308 biological process DNA catabolic process The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of (more detail) 25 NA Homo sapiens

GOA WAG000723 RNA Pol II CTD phosphorylation and interaction with CE (more detail) 25 NA Homo sapiens

Reactome WIG001730 Macrophage Differentiation and Growth Inhibition by METS Macrophage Differentiation and Growth Inhibition by METS (more detail) 25 NA Homo sapiens

Protein Lounge IEI008873 Protein protein interactors of human gene NLK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NLK (SwissProt ID=Q9 (more detail) 62 17535438 Homo sapiens

I2D TAX022715 GO:0035064 molecular function methylated histone binding Interacting selectively and non-covalently with a histone in which a residue has been modified by me (more detail) 62 NA Homo sapiens

GOA TAX031684 GO:0140034 molecular function methylation dependent protein binding Interacting selectively and non-covalently with a protein upon methylation of the target protein. (more detail) 62 NA Homo sapiens

GOA WIG001713 TREM1 Pathway TREM1 Pathway (more detail) 62 NA Homo sapiens

Protein Lounge IEI006482 Protein protein interactors of human gene IRF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IRF2 (SwissProt ID=P (more detail) 64 17535438 Homo sapiens

I2D MOX001045 Genes associated with Computational Drug Signature Fludarabine Genes associated with Computational Drug Signature Fludarabine, curated by the Drug Signature Databa (more detail) 66 25990557 Homo sapiens

DSigDB MOX000779 Genes associated with Computational Drug Signature Mehp Genes associated with Computational Drug Signature Mehp, curated by the Drug Signature Database (DSi (more detail) 66 25990557 Homo sapiens

DSigDB IEI005999 Protein protein interactors of human gene HP1BP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HP1BP3 (SwissProt ID (more detail) 66 17535438 Homo sapiens

I2D IEI013487 Protein protein interactors of human gene TCF12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCF12 (SwissProt ID= (more detail) 66 17535438 Homo sapiens

I2D IEI015128 Protein protein interactors of human gene XRCC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XRCC1 (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D IEI004088 Protein protein interactors of human gene ELK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELK1 (SwissProt ID=P (more detail) 51 17535438 Homo sapiens

I2D TAX032370 GO:1902099 biological process regulation of metaphase/anaphase transition of cell cycle Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cy (more detail) 51 NA Homo sapiens

GOA IEI015017 Protein protein interactors of human gene WDR61 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR61 (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D IEI011488 Protein protein interactors of human gene RPAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPAP2 (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D TAX025304 GO:0045840 biological process positive regulation of mitotic nuclear division Any process that activates or increases the frequency, rate or extent of mitosis. (more detail) 51 NA Homo sapiens

GOA IEI007701 Protein protein interactors of human gene MAPKAPK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPKAPK2 (SwissProt (more detail) 51 17535438 Homo sapiens

I2D IEI003771 Protein protein interactors of human gene DPY30 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DPY30 (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D TAX018443 GO:0015030 cellular component Cajal body A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in smal (more detail) 51 NA Homo sapiens

GOA WEX000040 HIF1 Signaling The genes related to hif1 signaling (signaling pathways) in tumor, immune, stroma using next-generat (more detail) 68 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI004244 Protein protein interactors of human gene ERBB4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERBB4 (SwissProt ID= (more detail) 68 17535438 Homo sapiens

I2D MOX004158 Genes associated with Computational Drug Signature gossypol Genes associated with Computational Drug Signature gossypol, curated by the Drug Signature Database (more detail) 68 25990557 Homo sapiens

DSigDB IEI011707 Protein protein interactors of human gene RUNX1T1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RUNX1T1 (SwissProt I (more detail) 70 17535438 Homo sapiens

I2D TAX020647 GO:0030808 biological process regulation of nucleotide biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 70 NA Homo sapiens

GOA MAX001258 Genes abnormally regulated in response to CD40L and IL4 [GeneID=959;3565] stimulation of B lymphocytes from patients with a hypomorphic mutation of IKBKG [GeneID=8517]. Hypomorphic mutations in the zinc finger domain of NF-kappaB essential modulator (NEMO) cause X-link (more detail) 70 NA Homo sapiens

MSigDB IEI013137 Protein protein interactors of human gene STN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STN1 (SwissProt ID=Q (more detail) 34 17535438 Homo sapiens

I2D IEI013338 Protein protein interactors of human gene TAF11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF11 (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D MOX004709 Genes associated with Computational Drug Signature suramin Genes associated with Computational Drug Signature suramin, curated by the Drug Signature Database ( (more detail) 34 25990557 Homo sapiens

DSigDB WIG000814 Genes involved in E2F mediated regulation of DNA replication (more detail) 34 NA Homo sapiens

MSigDB WIG000092 IL2 signaling events mediated by PI3K (more detail) 34 NA Homo sapiens

MSigDB MOX014987 Genes associated with Computational Drug Signature SB 203580 Genes associated with Computational Drug Signature SB 203580, curated by the Drug Signature Database (more detail) 34 25990557 Homo sapiens

DSigDB MOX000919 Genes associated with Computational Drug Signature Rhein Genes associated with Computational Drug Signature Rhein, curated by the Drug Signature Database (DS (more detail) 44 25990557 Homo sapiens

DSigDB FOX000601 Genes in the cancer module 280 (more detail) 44 NA Homo sapiens

MSigDB MOX003957 Genes associated with Computational Drug Signature dibutyl phthalate Genes associated with Computational Drug Signature dibutyl phthalate, curated by the Drug Signature (more detail) 44 25990557 Homo sapiens

DSigDB MOX003736 Genes associated with Computational Drug Signature berberine Genes associated with Computational Drug Signature berberine, curated by the Drug Signature Database (more detail) 44 25990557 Homo sapiens

DSigDB WIG000057 ErbB2/ErbB3 signaling events (more detail) 44 NA Homo sapiens

MSigDB TAX000300 Genes annotated by the GO term GO:0007254. A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress activated protein kinases, which in turn are a subfamily of mitogen activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress. (more detail) 44 NA Homo sapiens

MSigDB IEI003129 Protein protein interactors of human gene CTR9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTR9 (SwissProt ID=Q (more detail) 44 17535438 Homo sapiens

I2D IEI004707 Protein protein interactors of human gene FEN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FEN1 (SwissProt ID=P (more detail) 53 17535438 Homo sapiens

I2D IEI009441 Protein protein interactors of human gene PAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAF1 (SwissProt ID=Q (more detail) 53 17535438 Homo sapiens

I2D IEI009786 Protein protein interactors of human gene PFKL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PFKL (SwissProt ID=P (more detail) 53 17535438 Homo sapiens

I2D IEI008273 Protein protein interactors of human gene MSH3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MSH3 (SwissProt ID=P (more detail) 39 17535438 Homo sapiens

I2D IEI015839 Protein protein interactors of human gene ZSCAN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZSCAN1 (SwissProt ID (more detail) 39 17535438 Homo sapiens

I2D TAX032322 GO:1901985 biological process positive regulation of protein acetylation Any process that activates or increases the frequency, rate or extent of protein acetylation. (more detail) 39 NA Homo sapiens

GOA WIG000915 Genes involved in Interleukin 1 signaling (more detail) 39 NA Homo sapiens

MSigDB TAX034501 GO:2000144 biological process positive regulation of DNA templated transcription, initiation Any process that activates or increases the frequency, rate or extent of DNA-templated transcription (more detail) 28 NA Homo sapiens

GOA TAX023131 GO:0035872 biological process nucleotide binding domain, leucine rich repeat containing receptor signaling pathway A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine ric (more detail) 28 NA Homo sapiens

GOA TAX024363 GO:0043425 molecular function bHLH transcription factor binding Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily (more detail) 28 NA Homo sapiens

GOA MOX005343 Genes associated with Computational Drug Signature 1,9 Pyrazoloanthrone Genes associated with Computational Drug Signature 1,9-Pyrazoloanthrone, curated by the Drug Signatu (more detail) 28 25990557 Homo sapiens

DSigDB FOX000621 Genes in the cancer module 303 (more detail) 28 NA Homo sapiens

MSigDB MEX000305 Genes associated with Approved Drug vorinostat Genes associated with Approved Drug vorinostat, curated by the Drug Signature Database (DSigDB). (more detail) 28 25990557 Homo sapiens

DSigDB MEX001261 Genes associated with Kinase Inhibitor Torin 1 Genes associated with Kinase Inhibitor Torin 1, curated by the Drug Signature Database (DSigDB). (more detail) 28 25990557 Homo sapiens

DSigDB TAX015852 GO:0005657 cellular component replication fork The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands (more detail) 28 NA Homo sapiens

GOA WAG000471 Activation of the pre replicative complex (more detail) 28 NA Homo sapiens

Reactome FOX000609 Genes in the cancer module 29 (more detail) 28 NA Homo sapiens

MSigDB TAX013246 GO:0000083 biological process regulation of transcription involved in G1/S transition of mitotic cell cycle Any process that regulates transcription such that the target genes are involved in the transition b (more detail) 28 NA Homo sapiens

GOA IEI004325 Protein protein interactors of human gene ETS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ETS2 (SwissProt ID=P (more detail) 31 17535438 Homo sapiens

I2D IEI001237 Protein protein interactors of human gene BATF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BATF3 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI004368 Protein protein interactors of human gene EXOSC7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXOSC7 (SwissProt ID (more detail) 31 17535438 Homo sapiens

I2D IEI010234 Protein protein interactors of human gene POLR3D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR3D (SwissProt ID (more detail) 31 17535438 Homo sapiens

I2D IEI003431 Protein protein interactors of human gene DDX50 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX50 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI001429 Protein protein interactors of human gene BRD8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRD8 (SwissProt ID=Q (more detail) 31 17535438 Homo sapiens

I2D TAX034908 GO:2000758 biological process positive regulation of peptidyl lysine acetylation Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation (more detail) 31 NA Homo sapiens

GOA TAX000541 Genes annotated by the GO term GO:0016540. Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein. (more detail) 31 NA Homo sapiens

MSigDB MEX000765 Genes associated with Approved Drug methotrexate Genes associated with Approved Drug methotrexate, curated by the Drug Signature Database (DSigDB). (more detail) 31 25990557 Homo sapiens

DSigDB MOX004106 Genes associated with Computational Drug Signature floxuridine Genes associated with Computational Drug Signature floxuridine, curated by the Drug Signature Databa (more detail) 31 25990557 Homo sapiens

DSigDB MOX004768 Genes associated with Computational Drug Signature TIRON Genes associated with Computational Drug Signature TIRON, curated by the Drug Signature Database (DS (more detail) 31 25990557 Homo sapiens

DSigDB MEX001412 Genes associated with Kinase Inhibitor Tyrphostin AG 1478 Genes associated with Kinase Inhibitor Tyrphostin AG 1478, curated by the Drug Signature Database (D (more detail) 31 25990557 Homo sapiens

DSigDB MOX015675 Genes associated with Computational Drug Signature U 0126 Genes associated with Computational Drug Signature U-0126, curated by the Drug Signature Database (D (more detail) 31 25990557 Homo sapiens

DSigDB WIG000133 Regulation of p38 alpha and p38 beta (more detail) 31 NA Homo sapiens

MSigDB IEI014596 Protein protein interactors of human gene UBE2V2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2V2 (SwissProt ID (more detail) 55 17535438 Homo sapiens

I2D IEI007651 Protein protein interactors of human gene MAP2K7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP2K7 (SwissProt ID (more detail) 55 17535438 Homo sapiens

I2D IEI005086 Protein protein interactors of human gene GATAD2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GATAD2B (SwissProt I (more detail) 55 17535438 Homo sapiens

I2D IEI011130 Protein protein interactors of human gene RCC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RCC2 (SwissProt ID=Q (more detail) 46 17535438 Homo sapiens

I2D IEI003888 Protein protein interactors of human gene DZIP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DZIP3 (SwissProt ID= (more detail) 46 17535438 Homo sapiens

I2D TAX018967 GO:0016303 molecular function 1 phosphatidylinositol 3 kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3 (more detail) 46 NA Homo sapiens

GOA IEI007685 Protein protein interactors of human gene MAPK11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPK11 (SwissProt ID (more detail) 46 17535438 Homo sapiens

I2D IEI007503 Protein protein interactors of human gene LUC7L3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LUC7L3 (SwissProt ID (more detail) 46 17535438 Homo sapiens

I2D WAG001630 N Glycan biosynthesis N-glycans or asparagine-linked glycans are major constituents of glycoproteins in eukaryotes. N-glyc (more detail) 46 NA Homo sapiens

KEGG MOX004017 Genes associated with Computational Drug Signature 105156 22 7 Genes associated with Computational Drug Signature 105156-22-7, curated by the Drug Signature Databa (more detail) 57 25990557 Homo sapiens

DSigDB FOX000200 Neighborhood of RFC4 Neighborhood of RFC4 replication factor C (activator 1) 4, 37kDa in the GNF2 expression compendium (more detail) 57 NA Homo sapiens

MSigDB TAX034064 GO:1905818 biological process regulation of chromosome separation Any process that modulates the frequency, rate or extent of chromosome separation. (more detail) 59 NA Homo sapiens

GOA FOX000402 Neighborhood of SMC1L1 Neighborhood of SMC1L1 NULL in the MORF expression compendium (more detail) 59 NA Homo sapiens

MSigDB IEI011557 Protein protein interactors of human gene RPN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPN2 (SwissProt ID=P (more detail) 61 17535438 Homo sapiens

I2D TAX025682 GO:0046637 biological process regulation of alpha beta T cell differentiation Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation. (more detail) 61 NA Homo sapiens

GOA IEI010788 Protein protein interactors of human gene PWP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PWP1 (SwissProt ID=Q (more detail) 48 17535438 Homo sapiens

I2D IEI010103 Protein protein interactors of human gene PLOD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLOD1 (SwissProt ID= (more detail) 48 17535438 Homo sapiens

I2D IEI005578 Protein protein interactors of human gene GTF2E1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2E1 (SwissProt ID (more detail) 48 17535438 Homo sapiens

I2D IEI004367 Protein protein interactors of human gene EXOSC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXOSC6 (SwissProt ID (more detail) 48 17535438 Homo sapiens

I2D IEI012574 Protein protein interactors of human gene SLX1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLX1A (SwissProt ID= (more detail) 48 17535438 Homo sapiens

I2D FOX000059 Neighborhood of PFN1 Neighborhood of PFN1 profilin 1 in the GCM expression compendium (more detail) 48 NA Homo sapiens

MSigDB IEI012021 Protein protein interactors of human gene SERPINA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERPINA1 (SwissProt (more detail) 41 17535438 Homo sapiens

I2D TAX021098 GO:0031648 biological process protein destabilization Any process that decreases the stability of a protein, making it more vulnerable to degradative proc (more detail) 41 NA Homo sapiens

GOA IEI009852 Protein protein interactors of human gene PHF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHF6 (SwissProt ID=Q (more detail) 41 17535438 Homo sapiens

I2D IEI003425 Protein protein interactors of human gene DDX42 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX42 (SwissProt ID= (more detail) 41 17535438 Homo sapiens

I2D TAX000364 Genes annotated by the GO term GO:0030099. The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. (more detail) 36 NA Homo sapiens

MSigDB IEI002939 Protein protein interactors of human gene CPSF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CPSF3 (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D IEI007647 Protein protein interactors of human gene MAP2K3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP2K3 (SwissProt ID (more detail) 36 17535438 Homo sapiens

I2D IEI006388 Protein protein interactors of human gene ING2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ING2 (SwissProt ID=Q (more detail) 36 17535438 Homo sapiens

I2D TAX028646 GO:0061980 molecular function regulatory RNA binding Interacting selectively and non-covalently with a small regulatory RNA, a short RNA (usually 50-200 (more detail) 36 NA Homo sapiens

GOA WIG001736 Melanocyte Development and Pigmentation Melanocyte Development and Pigmentation (more detail) 36 NA Homo sapiens

Protein Lounge FEX001590 Leukemia Sanchez Guijo08 67genes Supplementary Table 2p. Genes differentially expressed in Normal bone marrow (BM) samples and comple (more detail) 63 18722011 Homo sapiens

GeneSigDB FOX000409 Neighborhood of TERF1 Neighborhood of TERF1 telomeric repeat binding factor (NIMA-interacting) 1 in the MORF expression c (more detail) 63 NA Homo sapiens

MSigDB WIG001498 Fc EpsilonRI Pathway Fc-EpsilonRI Pathway (more detail) 63 NA Homo sapiens

Protein Lounge WIG002032 SIDS Susceptibility Pathways SIDS Susceptibility Pathways (more detail) 65 NA Homo sapiens

WikiPathway TAX021797 GO:0032806 cellular component carboxy terminal domain protein kinase complex A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain rep (more detail) 24 NA Homo sapiens

GOA TAX019273 GO:0016875 molecular function ligase activity, forming carbon oxygen bonds Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis (more detail) 24 NA Homo sapiens

GOA TAX025418 GO:0046058 biological process cAMP metabolic process The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclo (more detail) 24 NA Homo sapiens

GOA TAX019032 GO:0016447 biological process somatic recombination of immunoglobulin gene segments The process in which immunoglobulin genes are formed through recombination of the germline genetic e (more detail) 24 NA Homo sapiens

GOA TAX023835 GO:0042430 biological process indole containing compound metabolic process The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) sk (more detail) 24 NA Homo sapiens

GOA TAX019816 GO:0019789 molecular function SUMO transferase activity Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO (more detail) 24 NA Homo sapiens

GOA IEI013711 Protein protein interactors of human gene TIMELESS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TIMELESS (SwissProt (more detail) 24 17535438 Homo sapiens

I2D TAX017609 GO:0009218 biological process pyrimidine ribonucleotide metabolic process The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of (more detail) 24 NA Homo sapiens

GOA TAX018802 GO:0015949 biological process nucleobase containing small molecule interconversion The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule i (more detail) 24 NA Homo sapiens

GOA TAX015407 GO:0004812 molecular function aminoacyl tRNA ligase activity Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diph (more detail) 24 NA Homo sapiens

GOA TAX001338 Genes annotated by the GO term GO:0004722. Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate. (more detail) 24 NA Homo sapiens

MSigDB PEX000547 DEAD: DEAD/DEAH box helicase Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding (more detail) 24 NA Homo sapiens

Pfam WIG001600 Nucleotide Excision Repair Pathway Nucleotide Excision Repair Pathway (more detail) 24 NA Homo sapiens

Protein Lounge TAX013434 GO:0000469 biological process cleavage involved in rRNA processing Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) tran (more detail) 24 NA Homo sapiens

GOA WAG001155 mRNA 3' end processing (more detail) 24 NA Homo sapiens

Reactome WAG000846 proteasome complex Attachment of the ubiquitin peptide to proteins targets them for proteolytic degradation by a comple (more detail) 24 NA Homo sapiens

BioCarta MEX001794 Genes associated with Kinase Inhibitor MLN8054 Genes associated with Kinase Inhibitor MLN8054, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB MEX002139 Genes associated with Kinase Inhibitor JAK Inhibitor I Genes associated with Kinase Inhibitor JAK Inhibitor I, curated by the Drug Signature Database (DSig (more detail) 24 25990557 Homo sapiens

DSigDB TAX000537 Genes annotated by the GO term GO:0006497. The covalent or non covalent attachment of lipid moieties to an amino acid in a protein. (more detail) 24 NA Homo sapiens

MSigDB WIG000971 Genes involved in Meiotic Recombination (more detail) 24 NA Homo sapiens

MSigDB MEX001309 Genes associated with Kinase Inhibitor CHEMBL552425 Genes associated with Kinase Inhibitor CHEMBL552425, curated by the Drug Signature Database (DSigDB) (more detail) 24 25990557 Homo sapiens

DSigDB WIG001308 Genes involved in tRNA Aminoacylation (more detail) 24 NA Homo sapiens

MSigDB MOX004722 Genes associated with Computational Drug Signature teniposide Genes associated with Computational Drug Signature teniposide, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens

DSigDB TAX016378 GO:0006506 biological process GPI anchor biosynthetic process The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GP (more detail) 24 NA Homo sapiens

GOA TAX001360 Genes annotated by the GO term GO:0003724. Catalysis of the unwinding of an RNA helix. (more detail) 24 NA Homo sapiens

MSigDB MEX002337 Genes associated with Kinase Inhibitor su6656 Genes associated with Kinase Inhibitor su6656, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB FEX002014 LungNotCaner Kent08 28genes Table 1b. Gene expression fold change of significantly regulated microarray genes: signalling pathwa (more detail) 24 18358739 Homo sapiens

GeneSigDB MEX001535 Genes associated with Kinase Inhibitor go 7874 Genes associated with Kinase Inhibitor go 7874, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB TAX016240 GO:0006297 biological process nucleotide excision repair, DNA gap filling Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand (more detail) 24 NA Homo sapiens

GOA WIG000820 Genes involved in Elongation arrest and recovery (more detail) 24 NA Homo sapiens

MSigDB WAG000206 O Glycan biosynthesis O-glycans are a class of glycans that modify serine or threonine residues of proteins. Biosynthesis (more detail) 24 NA Homo sapiens

KEGG TAX000142 Genes annotated by the GO term GO:0016569. The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups. (more detail) 24 NA Homo sapiens

MSigDB TAX001150 Genes annotated by the GO term GO:0004519. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. (more detail) 24 NA Homo sapiens

MSigDB MOX011953 Genes associated with Computational Drug Signature CI 1040 Genes associated with Computational Drug Signature CI-1040, curated by the Drug Signature Database ( (more detail) 24 25990557 Homo sapiens

DSigDB TAX013316 GO:0000228 cellular component nuclear chromosome A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during (more detail) 50 NA Homo sapiens

GOA WIG001705 Toll Like Receptors Pathway Toll-Like Receptors Pathway (more detail) 50 NA Homo sapiens

Protein Lounge IEI013150 Protein protein interactors of human gene STRBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STRBP (SwissProt ID= (more detail) 50 17535438 Homo sapiens

I2D IEI002048 Protein protein interactors of human gene CCNH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNH (SwissProt ID=P (more detail) 50 17535438 Homo sapiens

I2D IEI005643 Protein protein interactors of human gene H1 5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H1-5 (SwissProt ID=P (more detail) 50 17535438 Homo sapiens

I2D IEI014958 Protein protein interactors of human gene WARS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WARS1 (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D MAX001782 Interaction partners of class IIa histone deacetylases (HDAC). In the last decade, the identification of enzymes that regulate acetylation of histones and nonhisto (more detail) 43 NA Homo sapiens

MSigDB TAX001441 Genes annotated by the GO term GO:0004714. Catalysis of the reaction: ATP + a protein L tyrosine = ADP + a protein L tyrosine phosphate, to initiate a change in cell activity. (more detail) 43 NA Homo sapiens

MSigDB MOX004013 Genes associated with Computational Drug Signature Cleland's reagent Genes associated with Computational Drug Signature Cleland's reagent, curated by the Drug Signature (more detail) 43 25990557 Homo sapiens

DSigDB IEI003363 Protein protein interactors of human gene DCP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCP2 (SwissProt ID=Q (more detail) 52 17535438 Homo sapiens

I2D IEI006176 Protein protein interactors of human gene IFIT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFIT1 (SwissProt ID= (more detail) 52 17535438 Homo sapiens

I2D WIG000149 Signaling events mediated by PTP1B (more detail) 52 NA Homo sapiens

MSigDB WIG000510 Endometrial cancer Two types of endometrial carcinoma are distinguished with respect to biology and clinical course. Ty (more detail) 52 NA Homo sapiens

MSigDB WIG000970 Genes involved in Meiosis (more detail) 52 NA Homo sapiens

MSigDB WIG001093 Genes involved in Post NMDA receptor activation events (more detail) 33 NA Homo sapiens

MSigDB IEI009606 Protein protein interactors of human gene PCGF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCGF6 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D TAX027009 GO:0051443 biological process positive regulation of ubiquitin protein transferase activity Any process that activates, maintains or increases the rate of ubiquitin transferase activity. (more detail) 33 NA Homo sapiens

GOA IEI008261 Protein protein interactors of human gene MRTO4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRTO4 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI011784 Protein protein interactors of human gene SAP130 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SAP130 (SwissProt ID (more detail) 33 17535438 Homo sapiens

I2D IEI003545 Protein protein interactors of human gene DHX38 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHX38 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI008537 Protein protein interactors of human gene NACA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NACA (SwissProt ID=E (more detail) 54 17535438 Homo sapiens

I2D TAX027535 GO:0055021 biological process regulation of cardiac muscle tissue growth Any process that modulates the frequency, rate or extent of cardiac muscle growth. (more detail) 54 NA Homo sapiens

GOA MAX002342 The XPRSS Int network genes up regulated in breast tumors from patients with germline mutations in BRCA1 [GeneID=672] compared to those with the wild type allele. Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms (more detail) 54 NA Homo sapiens

MSigDB MOX017391 Genes associated with Computational Drug Signature Lapatinib Genes associated with Computational Drug Signature Lapatinib, curated by the Drug Signature Database (more detail) 54 25990557 Homo sapiens

DSigDB TAX021998 GO:0033146 biological process regulation of intracellular estrogen receptor signaling pathway Any process that modulates the frequency, rate or extent of the activity of an intracellular estroge (more detail) 38 NA Homo sapiens

GOA IEI010420 Protein protein interactors of human gene PRAME from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRAME (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D MOX007098 Genes associated with Computational Drug Signature Asterric acid Genes associated with Computational Drug Signature Asterric acid, curated by the Drug Signature Data (more detail) 38 25990557 Homo sapiens

DSigDB TAX016087 GO:0006040 biological process amino sugar metabolic process The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in p (more detail) 38 NA Homo sapiens

GOA IEI009851 Protein protein interactors of human gene PHF5A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHF5A (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D IEI011807 Protein protein interactors of human gene SATB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SATB1 (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D TAX000535 Genes annotated by the GO term GO:0046777. The phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. (more detail) 30 NA Homo sapiens

MSigDB WAG001007 trefoil factors initiate mucosal healing Maintaining the integrity of the gastrointestil tract despite the continual presence of microbial fl (more detail) 30 NA Homo sapiens

BioCarta MEX002110 Genes associated with Kinase Inhibitor AGN PC 0HSSYL Genes associated with Kinase Inhibitor AGN-PC-0HSSYL, curated by the Drug Signature Database (DSigDB (more detail) 30 25990557 Homo sapiens

DSigDB WIG001175 Genes involved in RNA Polymerase I Transcription (more detail) 27 NA Homo sapiens

MSigDB IEI009530 Protein protein interactors of human gene PAX3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAX3 (SwissProt ID=P (more detail) 27 17535438 Homo sapiens

I2D TAX028923 GO:0070423 biological process nucleotide binding oligomerization domain containing signaling pathway Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligom (more detail) 27 NA Homo sapiens

GOA IEI006596 Protein protein interactors of human gene JDP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JDP2 (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D FOX000633 Genes in the cancer module 318 (more detail) 27 NA Homo sapiens

MSigDB TAX022704 GO:0035035 molecular function histone acetyltransferase binding Interacting selectively and non-covalently with the enzyme histone acetyltransferase. (more detail) 27 NA Homo sapiens

GOA WIG001800 Blood Coagulation Cascade Blood Coagulation Cascade (more detail) 27 NA Homo sapiens

Protein Lounge IEI000554 Protein protein interactors of human gene ANAPC10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC10 (SwissProt I (more detail) 27 17535438 Homo sapiens

I2D WIG001067 Genes involved in PERK regulated gene expression (more detail) 27 NA Homo sapiens

MSigDB IEI001790 Protein protein interactors of human gene CARD11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CARD11 (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D TAX013322 GO:0000245 biological process spliceosomal complex assembly The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein app (more detail) 27 NA Homo sapiens

GOA TAX001243 Genes annotated by the GO term GO:0004222. Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides. Enzymes of this class contain a chelated metal ion essential to their catalytic activity at their active sites. (more detail) 27 NA Homo sapiens

MSigDB WAG000996 Glycan structures degradation (more detail) 27 NA Homo sapiens

KEGG IEI014983 Protein protein interactors of human gene WDR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR1 (SwissProt ID=O (more detail) 45 17535438 Homo sapiens

I2D WIG001038 Genes involved in Nucleotide binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (more detail) 45 NA Homo sapiens

MSigDB MOX003922 Genes associated with Computational Drug Signature p,p' DDE Genes associated with Computational Drug Signature p,p'-DDE, curated by the Drug Signature Database (more detail) 45 25990557 Homo sapiens

DSigDB WIG000185 TNF receptor signaling pathway (more detail) 45 NA Homo sapiens

MSigDB TAX014038 GO:0002065 biological process columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cub (more detail) 45 NA Homo sapiens

GOA IEI005504 Protein protein interactors of human gene GRIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRIN1 (SwissProt ID= (more detail) 56 17535438 Homo sapiens

I2D IEI008980 Protein protein interactors of human gene NPEPPS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NPEPPS (SwissProt ID (more detail) 56 17535438 Homo sapiens

I2D IEI010152 Protein protein interactors of human gene PNKP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PNKP (SwissProt ID=Q (more detail) 56 17535438 Homo sapiens

I2D TAX000187 Genes annotated by the GO term GO:0009790. The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. (more detail) 56 NA Homo sapiens

MSigDB MOX017021 Genes associated with Computational Drug Signature gossypol Genes associated with Computational Drug Signature gossypol, curated by the Drug Signature Database (more detail) 56 25990557 Homo sapiens

DSigDB IEI001955 Protein protein interactors of human gene CCDC50 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCDC50 (SwissProt ID (more detail) 58 17535438 Homo sapiens

I2D IEI003685 Protein protein interactors of human gene DNAJC7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJC7 (SwissProt ID (more detail) 58 17535438 Homo sapiens

I2D MOX003036 Genes associated with Computational Drug Signature Pterostilbene Genes associated with Computational Drug Signature Pterostilbene, curated by the Drug Signature Data (more detail) 58 25990557 Homo sapiens

DSigDB WAG000254 HIF 1 alpha transcription factor network (more detail) 60 NA Homo sapiens

NCI-Nature Curated WIG001535 Aldosterone Signaling in Epithelial Cells Aldosterone Signaling in Epithelial Cells (more detail) 60 NA Homo sapiens

Protein Lounge MOX002477 Genes associated with Computational Drug Signature bisindolylmaleimide i Genes associated with Computational Drug Signature bisindolylmaleimide i, curated by the Drug Signat (more detail) 62 25990557 Homo sapiens

DSigDB IEI014563 Protein protein interactors of human gene UBE2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2A (SwissProt ID= (more detail) 62 17535438 Homo sapiens

I2D IEI001240 Protein protein interactors of human gene BAZ1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BAZ1B (SwissProt ID= (more detail) 62 17535438 Homo sapiens

I2D IEI001822 Protein protein interactors of human gene CASP6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASP6 (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D TAX025668 GO:0046622 biological process positive regulation of organ growth Any process that activates or increases the frequency, rate or extent of growth of an organ of an or (more detail) 47 NA Homo sapiens

GOA TAX034456 GO:2000059 biological process negative regulation of ubiquitin dependent protein catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent pr (more detail) 47 NA Homo sapiens

GOA WIG000097 IL6 mediated signaling events (more detail) 47 NA Homo sapiens

MSigDB FEX001611 Leukemia Hernandez09 66genes Table 3. Most relevant differentially expressed genes in patients with 80% or more cells showing 13q (more detail) 64 19252174 Homo sapiens

GeneSigDB IEI009544 Protein protein interactors of human gene PBX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PBX1 (SwissProt ID=P (more detail) 40 17535438 Homo sapiens

I2D IEI004938 Protein protein interactors of human gene FUBP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FUBP3 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D IEI014997 Protein protein interactors of human gene WDR33 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR33 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D IEI002179 Protein protein interactors of human gene CDC25C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC25C (SwissProt ID (more detail) 40 17535438 Homo sapiens

I2D WIG000084 IFN gamma pathway (more detail) 40 NA Homo sapiens

MSigDB WIG000487 Bladder cancer Bladder cancer arise and progress along two distinctive pathways. The first of these is often preced (more detail) 40 NA Homo sapiens

MSigDB TAX013362 GO:0000307 cellular component cyclin dependent protein kinase holoenzyme complex Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit (more detail) 40 NA Homo sapiens

GOA FOX000070 Neighborhood of RAF1 Neighborhood of RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 in the GCM expression compend (more detail) 40 NA Homo sapiens

MSigDB IEI005639 Protein protein interactors of human gene H1 10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H1-10 (SwissProt ID= (more detail) 66 17535438 Homo sapiens

I2D IEI007597 Protein protein interactors of human gene MAGED2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAGED2 (SwissProt ID (more detail) 66 17535438 Homo sapiens

I2D WIG000608 Renal cell carcinoma Renal cell carcinoma (RCC) is a heterogenous term comprising a group of neoplasms of renal origin. T (more detail) 66 NA Homo sapiens

MSigDB MOX000228 Genes associated with Computational Drug Signature SANGUINARINE Genes associated with Computational Drug Signature SANGUINARINE, curated by the Drug Signature Datab (more detail) 66 25990557 Homo sapiens

DSigDB WIG001610 Androgen Signaling Androgen Signaling (more detail) 66 NA Homo sapiens

Protein Lounge TAX017229 GO:0008378 molecular function galactosyltransferase activity Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydr (more detail) 35 NA Homo sapiens

GOA IEI011202 Protein protein interactors of human gene RFC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RFC3 (SwissProt ID=P (more detail) 35 17535438 Homo sapiens

I2D IEI004855 Protein protein interactors of human gene FOSL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOSL1 (SwissProt ID= (more detail) 35 17535438 Homo sapiens

I2D IEI005650 Protein protein interactors of human gene H2AC18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AC18 (SwissProt ID (more detail) 35 17535438 Homo sapiens

I2D IEI015059 Protein protein interactors of human gene WIZ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WIZ (SwissProt ID=O9 (more detail) 35 17535438 Homo sapiens

I2D IEI009331 Protein protein interactors of human gene ORC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ORC1 (SwissProt ID=Q (more detail) 35 17535438 Homo sapiens

I2D MOX003679 Genes associated with Computational Drug Signature amsacrine Genes associated with Computational Drug Signature amsacrine, curated by the Drug Signature Database (more detail) 35 25990557 Homo sapiens

DSigDB WIG000596 Prion diseases Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal n (more detail) 35 NA Homo sapiens

MSigDB IEI011055 Protein protein interactors of human gene RBBP8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBBP8 (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D TAX020288 GO:0030071 biological process regulation of mitotic metaphase/anaphase transition Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell p (more detail) 49 NA Homo sapiens

GOA IEI003551 Protein protein interactors of human gene DIABLO from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIABLO (SwissProt ID (more detail) 49 17535438 Homo sapiens

I2D TAX025173 GO:0045620 biological process negative regulation of lymphocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentia (more detail) 49 NA Homo sapiens

GOA IEI011436 Protein protein interactors of human gene RNF31 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF31 (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D TAX025476 GO:0046148 biological process pigment biosynthetic process The chemical reactions and pathways resulting in the formation of a pigment, any general or particul (more detail) 49 NA Homo sapiens

GOA IEI007834 Protein protein interactors of human gene MECP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MECP2 (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D MOX006249 Genes associated with Computational Drug Signature 5H quinolino[8,7 c][1,2]benzothiazine 6,6 dioxide Genes associated with Computational Drug Signature 5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide (more detail) 51 25990557 Homo sapiens

DSigDB MOX003868 Genes associated with Computational Drug Signature clofibrate Genes associated with Computational Drug Signature clofibrate, curated by the Drug Signature Databas (more detail) 51 25990557 Homo sapiens

DSigDB MOX016924 Genes associated with Computational Drug Signature ethopropazine Genes associated with Computational Drug Signature ethopropazine, curated by the Drug Signature Data (more detail) 51 25990557 Homo sapiens

DSigDB IEI003124 Protein protein interactors of human gene CTNNBL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTNNBL1 (SwissProt I (more detail) 51 17535438 Homo sapiens

I2D WIG001119 Genes involved in Pyrimidine metabolism (more detail) 23 NA Homo sapiens

MSigDB TAX023288 GO:0036152 biological process phosphatidylethanolamine acyl chain remodeling Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylat (more detail) 23 NA Homo sapiens

GOA TAX023848 GO:0042451 biological process purine nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a fa (more detail) 23 NA Homo sapiens

GOA TAX017483 GO:0009067 biological process aspartate family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the aspartate famil (more detail) 23 NA Homo sapiens

GOA TAX013435 GO:0000470 biological process maturation of LSU rRNA Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molec (more detail) 23 NA Homo sapiens

GOA TAX000260 Genes annotated by the GO term GO:0016570. The covalent alteration of one or more amino acid residues within a histone protein. (more detail) 23 NA Homo sapiens

MSigDB WIG001167 Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter (more detail) 23 NA Homo sapiens

MSigDB TAX019487 GO:0018198 biological process peptidyl cysteine modification The modification of peptidyl-cysteine. (more detail) 23 NA Homo sapiens

GOA TAX015892 GO:0005732 cellular component small nucleolar ribonucleoprotein complex A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family (more detail) 23 NA Homo sapiens

GOA TAX016153 GO:0006144 biological process purine nucleobase metabolic process The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen (more detail) 23 NA Homo sapiens

GOA TAX017656 GO:0009310 biological process amine catabolic process The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakl (more detail) 23 NA Homo sapiens

GOA WIG001103 Genes involved in Processing of Capped Intronless Pre mRNA (more detail) 23 NA Homo sapiens

MSigDB MEX002221 Genes associated with Kinase Inhibitor Sunitinib Genes associated with Kinase Inhibitor Sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens

DSigDB MEX002057 Genes associated with Kinase Inhibitor Kinome 800 Genes associated with Kinase Inhibitor Kinome_800, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens

DSigDB WIG001180 Genes involved in RORA Activates Circadian Expression (more detail) 23 NA Homo sapiens

MSigDB WIG001468 DNA Methylation and Transcriptional Repression DNA Methylation and Transcriptional Repression (more detail) 23 NA Homo sapiens

Protein Lounge WIG000334 Inhibition of Cellular Proliferation by Gleevec The drug Gleevec (also known as imatinib mesylate or STI-571) was approved by the FDA in 2001 for th (more detail) 23 NA Homo sapiens

MSigDB TAX020843 GO:0031146 biological process SCF dependent proteasomal ubiquitin dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 23 NA Homo sapiens

GOA TAX028682 GO:0070006 molecular function metalloaminopeptidase activity Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanis (more detail) 23 NA Homo sapiens

GOA TAX025465 GO:0046129 biological process purine ribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucle (more detail) 23 NA Homo sapiens

GOA MAX003001 Genes whose expression most significantly correlated with cancer cell line sensitivity to the proapoptotic ligand APO2 [GeneID=8797]. Apo2L/TRAIL stimulates cancer cell death through the proapoptotic receptors DR4 and DR5, but the det (more detail) 23 NA Homo sapiens

MSigDB MEX001418 Genes associated with Kinase Inhibitor TSU 68 Genes associated with Kinase Inhibitor TSU-68, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens

DSigDB FOX000462 Genes in the cancer module 130 (more detail) 23 NA Homo sapiens

MSigDB TAX013458 GO:0000715 biological process nucleotide excision repair, DNA damage recognition The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky (more detail) 23 NA Homo sapiens

GOA TAX018899 GO:0016180 biological process snRNA processing Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a matu (more detail) 23 NA Homo sapiens

GOA WIG001634 Polyamine Regulation in Colon Cancer Polyamine Regulation in Colon Cancer (more detail) 23 NA Homo sapiens

Protein Lounge WIG000562 Mismatch repair DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintain (more detail) 23 NA Homo sapiens

MSigDB TAX023815 GO:0042402 biological process cellular biogenic amine catabolic process The chemical reactions and pathways occurring at the level of individual cells resulting in the brea (more detail) 23 NA Homo sapiens

GOA TAX022279 GO:0034035 biological process purine ribonucleoside bisphosphate metabolic process The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consi (more detail) 23 NA Homo sapiens

GOA TAX016381 GO:0006509 biological process membrane protein ectodomain proteolysis The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular do (more detail) 23 NA Homo sapiens

GOA TAX016589 GO:0006779 biological process porphyrin containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of any member of a large group of der (more detail) 23 NA Homo sapiens

GOA WIG000877 Genes involved in Glutathione conjugation (more detail) 23 NA Homo sapiens

MSigDB WIG000693 Genes involved in Amyloids (more detail) 23 NA Homo sapiens

MSigDB IEI001476 Protein protein interactors of human gene BTG2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BTG2 (SwissProt ID=P (more detail) 23 17535438 Homo sapiens

I2D WAG000199 Sulfur metabolism Sulfur is an essential element for life and the metabolism of organic sulfur compounds plays an impo (more detail) 23 NA Homo sapiens

KEGG FEX002584 Prostate Wang02 25genes Table 1 Candidate genes responsive to (-) epigallocatechin-3-gallate in human prostate cancer LNCaP (more detail) 23 12175522 Homo sapiens

GeneSigDB IEI002180 Protein protein interactors of human gene CDC26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC26 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D TAX026447 GO:0050427 biological process 3' phosphoadenosine 5' phosphosulfate metabolic process The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occ (more detail) 23 NA Homo sapiens

GOA TAX020685 GO:0030878 biological process thyroid gland development The process whose specific outcome is the progression of the thyroid gland over time, from its forma (more detail) 23 NA Homo sapiens

GOA MEX002206 Genes associated with Kinase Inhibitor BI 2536 Genes associated with Kinase Inhibitor BI 2536, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens

DSigDB IEI007591 Protein protein interactors of human gene MAGEB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAGEB2 (SwissProt ID (more detail) 42 17535438 Homo sapiens

I2D IEI008035 Protein protein interactors of human gene MLLT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MLLT3 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D IEI011374 Protein protein interactors of human gene RNF10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF10 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D MOX004880 Genes associated with Computational Drug Signature 124020 07 1 Genes associated with Computational Drug Signature 124020-07-1, curated by the Drug Signature Databa (more detail) 42 25990557 Homo sapiens

DSigDB WIG001920 TWEAK Signaling Pathway TWEAK Signaling Pathway (more detail) 42 NA Homo sapiens

WikiPathway MAX000059 Genes whose expression peaked at 40 min after stimulation of HeLa cells with EGF [GeneID=1950]. Signaling pathways invoke interplays between forward signaling and feedback to drive robust cellular (more detail) 42 NA Homo sapiens

MSigDB WIG001960 IL 6 signaling pathway IL-6 signaling pathway (more detail) 42 NA Homo sapiens

WikiPathway WIG000127 Role of Calcineurin dependent NFAT signaling in lymphocytes (more detail) 53 NA Homo sapiens

MSigDB IEI010162 Protein protein interactors of human gene PNN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PNN (SwissProt ID=Q9 (more detail) 53 17535438 Homo sapiens

I2D IEI005574 Protein protein interactors of human gene GTF2A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2A1 (SwissProt ID (more detail) 53 17535438 Homo sapiens

I2D IEI011926 Protein protein interactors of human gene SEC16A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SEC16A (SwissProt ID (more detail) 53 17535438 Homo sapiens

I2D IEI003881 Protein protein interactors of human gene DYRK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DYRK2 (SwissProt ID= (more detail) 53 17535438 Homo sapiens

I2D FEX002236 Lymphoma Zhu05 61genes Table 1. Microarray analysis of mRNA expression in a comparison of FRS-transfected cells and control (more detail) 53 15897243 Homo sapiens

GeneSigDB TAX028428 GO:0061418 biological process regulation of transcription from RNA polymerase II promoter in response to hypoxia Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II (more detail) 32 NA Homo sapiens

GOA IEI015084 Protein protein interactors of human gene WRNIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WRNIP1 (SwissProt ID (more detail) 32 17535438 Homo sapiens

I2D IEI005081 Protein protein interactors of human gene GATA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GATA4 (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D TAX001432 Genes annotated by the GO term GO:0016782. Catalysis of the transfer of a sulfur containing group from one compound (donor) to another (acceptor). (more detail) 32 NA Homo sapiens

MSigDB WIG000005 Alpha synuclein signaling (more detail) 32 NA Homo sapiens

MSigDB MAX000764 Genes required for CTNNB1 [GeneID=1499] activity in DLD 1 cell (colon cancer with APC [GeneID=324] deletions), based on shRNA screen. Aberrant activation of the canonical WNT/beta-catenin pathway occurs in almost all colorectal cancer (more detail) 32 NA Homo sapiens

MSigDB WIG000218 ERK1/ERK2 MAPK Pathway na (more detail) 32 NA Homo sapiens

MSigDB TAX000977 Genes annotated by the GO term GO:0016604. Extra nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. (more detail) 32 NA Homo sapiens

MSigDB IEI007573 Protein protein interactors of human gene MAFG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAFG (SwissProt ID=O (more detail) 37 17535438 Homo sapiens

I2D MOX000411 Genes associated with Computational Drug Signature piperine Genes associated with Computational Drug Signature piperine, curated by the Drug Signature Database (more detail) 37 25990557 Homo sapiens

DSigDB MOX012913 Genes associated with Computational Drug Signature gossypol Genes associated with Computational Drug Signature gossypol, curated by the Drug Signature Database (more detail) 55 25990557 Homo sapiens

DSigDB MOX013676 Genes associated with Computational Drug Signature methylene blue Genes associated with Computational Drug Signature methylene blue, curated by the Drug Signature Dat (more detail) 55 25990557 Homo sapiens

DSigDB FEX000087 BoneMarrow Zhan02 69genes Table 5. The 70 most significantly up-regulated genes in MM in comparison with normal bone marrow PC (more detail) 55 11861292 Homo sapiens

GeneSigDB IEI010661 Protein protein interactors of human gene PSME2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSME2 (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D IEI003813 Protein protein interactors of human gene DTL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DTL (SwissProt ID=Q9 (more detail) 44 17535438 Homo sapiens

I2D MOX003473 Genes associated with Computational Drug Signature dorsomorphin Genes associated with Computational Drug Signature dorsomorphin, curated by the Drug Signature Datab (more detail) 44 25990557 Homo sapiens

DSigDB WIG001615 Parkinson's Disease Pathway Parkinson's Disease Pathway (more detail) 44 NA Homo sapiens

Protein Lounge MOX006430 Genes associated with Computational Drug Signature 9 Methoxyellipticine Genes associated with Computational Drug Signature 9-Methoxyellipticine, curated by the Drug Signatu (more detail) 44 25990557 Homo sapiens

DSigDB MAX003123 A list of known cell cycle regulated genes that was compiled from the literature by the authors. The genome-wide program of gene expression during the cell division cycle in a human cancer cell lin (more detail) 44 NA Homo sapiens

MSigDB WIG001943 IL 3 Signaling Pathway IL-3 Signaling Pathway (more detail) 44 NA Homo sapiens

WikiPathway WIG000131 Notch signaling pathway (more detail) 57 NA Homo sapiens

MSigDB IEI003190 Protein protein interactors of human gene CXCL8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CXCL8 (SwissProt ID= (more detail) 57 17535438 Homo sapiens

I2D IEI012992 Protein protein interactors of human gene SRRT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRRT (SwissProt ID=Q (more detail) 57 17535438 Homo sapiens

I2D IEI005862 Protein protein interactors of human gene HK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HK1 (SwissProt ID=P1 (more detail) 57 17535438 Homo sapiens

I2D IEI000555 Protein protein interactors of human gene ANAPC11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC11 (SwissProt I (more detail) 29 17535438 Homo sapiens

I2D IEI001960 Protein protein interactors of human gene CCDC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCDC6 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI014579 Protein protein interactors of human gene UBE2J1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2J1 (SwissProt ID (more detail) 29 17535438 Homo sapiens

I2D IEI004188 Protein protein interactors of human gene EP400 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EP400 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI007282 Protein protein interactors of human gene LIN28B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LIN28B (SwissProt ID (more detail) 29 17535438 Homo sapiens

I2D TAX025334 GO:0045910 biological process negative regulation of DNA recombination Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination. (more detail) 29 NA Homo sapiens

GOA TAX025247 GO:0045738 biological process negative regulation of DNA repair Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair. (more detail) 29 NA Homo sapiens

GOA MOX013523 Genes associated with Computational Drug Signature LY 294002 Genes associated with Computational Drug Signature LY 294002, curated by the Drug Signature Database (more detail) 29 25990557 Homo sapiens

DSigDB MOX005959 Genes associated with Computational Drug Signature 4,5,6,7 tetrabromobenzotriazole Genes associated with Computational Drug Signature 4,5,6,7-tetrabromobenzotriazole, curated by the D (more detail) 29 25990557 Homo sapiens

DSigDB TAX028264 GO:0061035 biological process regulation of cartilage development Any process that modulates the rate, frequency, or extent of cartilage development, the process whos (more detail) 59 NA Homo sapiens

GOA IEI015324 Protein protein interactors of human gene ZFR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZFR (SwissProt ID=Q9 (more detail) 59 17535438 Homo sapiens

I2D IEI001418 Protein protein interactors of human gene BRAF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRAF (SwissProt ID=P (more detail) 59 17535438 Homo sapiens

I2D IEI007561 Protein protein interactors of human gene MAD2L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAD2L1 (SwissProt ID (more detail) 59 17535438 Homo sapiens

I2D IEI007472 Protein protein interactors of human gene LSM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSM2 (SwissProt ID=Q (more detail) 59 17535438 Homo sapiens

I2D MOX016086 Genes associated with Computational Drug Signature 3 methyladenine Genes associated with Computational Drug Signature 3-methyladenine, curated by the Drug Signature Da (more detail) 59 25990557 Homo sapiens

DSigDB TAX000718 Genes annotated by the GO term GO:0009314. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. (more detail) 59 NA Homo sapiens

MSigDB TAX001424 Genes annotated by the GO term GO:0016746. Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). (more detail) 59 NA Homo sapiens

MSigDB TAX013343 GO:0000280 biological process nuclear division The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed betw (more detail) 59 NA Homo sapiens

GOA WIG001714 TRKA Signaling TRKA Signaling (more detail) 59 NA Homo sapiens

Protein Lounge IEI011098 Protein protein interactors of human gene RBM7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM7 (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens

I2D TAX033892 GO:1905354 cellular component exoribonuclease complex A protein complex which is capable of exoribonuclease activity. (more detail) 26 NA Homo sapiens

GOA TAX025582 GO:0046466 biological process membrane lipid catabolic process The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found i (more detail) 26 NA Homo sapiens

GOA TAX033410 GO:1904357 biological process negative regulation of telomere maintenance via telomere lengthening Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance vi (more detail) 26 NA Homo sapiens

GOA TAX020996 GO:0031440 biological process regulation of mRNA 3' end processing Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process invo (more detail) 26 NA Homo sapiens

GOA TAX033406 GO:1904353 biological process regulation of telomere capping Any process that modulates the frequency, rate or extent of telomere capping. (more detail) 26 NA Homo sapiens

GOA WIG001168 Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter (more detail) 26 NA Homo sapiens

MSigDB TAX013295 GO:0000178 cellular component exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuc (more detail) 26 NA Homo sapiens

GOA WIG001236 Genes involved in Sphingolipid de novo biosynthesis (more detail) 26 NA Homo sapiens

MSigDB WIG002012 EPO Receptor Signaling EPO Receptor Signaling (more detail) 26 NA Homo sapiens

WikiPathway TAX016377 GO:0006505 biological process GPI anchor metabolic process The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechan (more detail) 26 NA Homo sapiens

GOA WIG000417 Influence of Ras and Rho proteins on G1 to S Transition The cell cycle transition from G1 to S phase is a key regulatory point in the cell cycle. This trans (more detail) 26 NA Homo sapiens

MSigDB IEI011747 Protein protein interactors of human gene S100A8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene S100A8 (SwissProt ID (more detail) 61 17535438 Homo sapiens

I2D TAX016864 GO:0007249 biological process I kappaB kinase/NF kappaB signaling The process in which a signal is passed on to downstream components within the cell through the I-ka (more detail) 61 NA Homo sapiens

GOA IEI014236 Protein protein interactors of human gene TRIM32 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM32 (SwissProt ID (more detail) 63 17535438 Homo sapiens

I2D IEI003663 Protein protein interactors of human gene DNAJC10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJC10 (SwissProt I (more detail) 63 17535438 Homo sapiens

I2D IEI005934 Protein protein interactors of human gene HNRNPCL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPCL1 (SwissProt (more detail) 63 17535438 Homo sapiens

I2D IEI007671 Protein protein interactors of human gene MAP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP4 (SwissProt ID=P (more detail) 63 17535438 Homo sapiens

I2D IEI009021 Protein protein interactors of human gene NR1H2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR1H2 (SwissProt ID= (more detail) 63 17535438 Homo sapiens

I2D MEX004339 Genes associated with Perturbagen Signature trimipramine Genes associated with Perturbagen Signature trimipramine, curated by the Drug Signature Database (DS (more detail) 63 25990557 Homo sapiens

DSigDB TAX000616 Genes annotated by the GO term GO:0051101. Any process that modulates the frequency, rate or extent of DNA binding, selective interaction with deoxyribonucleic acid. (more detail) 46 NA Homo sapiens

MSigDB MOX001095 Genes associated with Computational Drug Signature 2 [6 fluoro 2 methyl 3 [(4 methylsulfonylphenyl)methylidene]inden 1 yl]acetic acid Genes associated with Computational Drug Signature 2-[6-fluoro-2-methyl-3-[(4-methylsulfonylphenyl)m (more detail) 46 25990557 Homo sapiens

DSigDB IEI004365 Protein protein interactors of human gene EXOSC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXOSC4 (SwissProt ID (more detail) 46 17535438 Homo sapiens

I2D IEI008013 Protein protein interactors of human gene MKI67 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MKI67 (SwissProt ID= (more detail) 39 17535438 Homo sapiens

I2D TAX027632 GO:0060043 biological process regulation of cardiac muscle cell proliferation Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation. (more detail) 39 NA Homo sapiens

GOA WIG000555 Lysine degradation (more detail) 39 NA Homo sapiens

MSigDB IEI004366 Protein protein interactors of human gene EXOSC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXOSC5 (SwissProt ID (more detail) 48 17535438 Homo sapiens

I2D TAX019676 GO:0019319 biological process hexose biosynthetic process The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a (more detail) 48 NA Homo sapiens

GOA IEI007132 Protein protein interactors of human gene LAMP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LAMP2 (SwissProt ID= (more detail) 48 17535438 Homo sapiens

I2D TAX000979 Genes annotated by the GO term GO:0000228. A chromosome found in the nucleus of a eukaryotic cell. (more detail) 48 NA Homo sapiens

MSigDB WIG000500 Cysteine and methionine metabolism Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine throu (more detail) 34 NA Homo sapiens

MSigDB WAG001262 IL2 signaling events mediated by PI3K (more detail) 34 NA Homo sapiens

NCI-Nature Curated MOX000631 Genes associated with Computational Drug Signature MANCOZEB Genes associated with Computational Drug Signature MANCOZEB, curated by the Drug Signature Database (more detail) 34 25990557 Homo sapiens

DSigDB WAG000258 FAS signaling pathway (CD95) (more detail) 34 NA Homo sapiens

NCI-Nature Curated IEI014601 Protein protein interactors of human gene UBE3C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE3C (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D TAX032682 GO:1902893 biological process regulation of pri miRNA transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of pri-miRNA transcription mediated by RNA (more detail) 34 NA Homo sapiens

GOA TAX019657 GO:0019239 molecular function deaminase activity Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3). (more detail) 34 NA Homo sapiens

GOA TAX019219 GO:0016790 molecular function thiolester hydrolase activity Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiole (more detail) 34 NA Homo sapiens

GOA IEI006178 Protein protein interactors of human gene IFIT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFIT2 (SwissProt ID= (more detail) 50 17535438 Homo sapiens

I2D TAX023151 GO:0035914 biological process skeletal muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal mus (more detail) 50 NA Homo sapiens

GOA IEI014656 Protein protein interactors of human gene UFM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UFM1 (SwissProt ID=P (more detail) 50 17535438 Homo sapiens

I2D WIG000007 Angiopoietin receptor Tie2 mediated signaling (more detail) 50 NA Homo sapiens

MSigDB WIG001518 GDNF Family Ligands and Receptor Interactions GDNF-Family Ligands and Receptor Interactions (more detail) 50 NA Homo sapiens

Protein Lounge MEX000234 Genes associated with Approved Drug niclosamide Genes associated with Approved Drug niclosamide, curated by the Drug Signature Database (DSigDB). (more detail) 50 25990557 Homo sapiens

DSigDB IEI007737 Protein protein interactors of human gene MAST3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAST3 (SwissProt ID= (more detail) 41 17535438 Homo sapiens

I2D IEI001749 Protein protein interactors of human gene CAMK2G from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAMK2G (SwissProt ID (more detail) 41 17535438 Homo sapiens

I2D WIG001497 Fas Signaling Fas Signaling (more detail) 41 NA Homo sapiens

Protein Lounge WAG001619 Pentose phosphate pathway The pentose phosphate pathway is a process of glucose turnover that produces DPH as reducing equival (more detail) 41 NA Homo sapiens

KEGG TAX026066 GO:0048146 biological process positive regulation of fibroblast proliferation Any process that activates or increases the frequency, rate or extent of multiplication or reproduct (more detail) 52 NA Homo sapiens

GOA FEX001597 Leukemia Lee08 66genes Table 2. Genes highly expressed in MM6 cells (more detail) 52 18931459 Homo sapiens

GeneSigDB TAX018256 GO:0010965 biological process regulation of mitotic sister chromatid separation Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mit (more detail) 54 NA Homo sapiens

GOA IEI001228 Protein protein interactors of human gene BAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BAP1 (SwissProt ID=Q (more detail) 54 17535438 Homo sapiens

I2D IEI003060 Protein protein interactors of human gene CSNK1D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSNK1D (SwissProt ID (more detail) 54 17535438 Homo sapiens

I2D WIG001777 VEGF Pathway VEGF Pathway (more detail) 54 NA Homo sapiens

Protein Lounge WIG000182 TGF beta receptor signaling (more detail) 54 NA Homo sapiens

MSigDB TAX022907 GO:0035510 biological process DNA dealkylation The removal of an alkyl group from one or more nucleotides within an DNA molecule. (more detail) 22 NA Homo sapiens

GOA TAX019225 GO:0016799 molecular function hydrolase activity, hydrolyzing N glycosyl compounds Catalysis of the hydrolysis of any N-glycosyl bond. (more detail) 22 NA Homo sapiens

GOA TAX032235 GO:1901687 biological process glutathione derivative biosynthetic process The chemical reactions and pathways resulting in the formation of glutathione derivative. (more detail) 22 NA Homo sapiens

GOA TAX019278 GO:0016881 molecular function acid amino acid ligase activity Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomita (more detail) 22 NA Homo sapiens

GOA TAX032234 GO:1901685 biological process glutathione derivative metabolic process The chemical reactions and pathways involving glutathione derivative. (more detail) 22 NA Homo sapiens

GOA TAX019104 GO:0016578 biological process histone deubiquitination The modification of histones by removal of ubiquitin groups. (more detail) 22 NA Homo sapiens

GOA TAX019290 GO:0016894 molecular function endonuclease activity, active with either ribo or deoxyribonucleic acids and producing 3' phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yi (more detail) 22 NA Homo sapiens

GOA WEX000015 Circadian Clock The genes related to circadian clock (physiology & disease) in tumor, immune, stroma using next-gene (more detail) 22 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas TAX017655 GO:0009309 biological process amine biosynthetic process The chemical reactions and pathways resulting in the formation of any organic compound that is weakl (more detail) 22 NA Homo sapiens

GOA TAX017611 GO:0009220 biological process pyrimidine ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a com (more detail) 22 NA Homo sapiens

GOA TAX020330 GO:0030149 biological process sphingolipid catabolic process The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of l (more detail) 22 NA Homo sapiens

GOA TAX017545 GO:0009147 biological process pyrimidine nucleoside triphosphate metabolic process The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consist (more detail) 22 NA Homo sapiens

GOA TAX022129 GO:0033522 biological process histone H2A ubiquitination The modification of histone H2A by addition of one or more ubiquitin groups. (more detail) 22 NA Homo sapiens

GOA IEI010948 Protein protein interactors of human gene RAD54L2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD54L2 (SwissProt I (more detail) 22 17535438 Homo sapiens

I2D TAX025471 GO:0046135 biological process pyrimidine nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecul (more detail) 22 NA Homo sapiens

GOA TAX028694 GO:0070034 molecular function telomerase RNA binding Interacting selectively and non-covalently with the telomerase RNA template. (more detail) 22 NA Homo sapiens

GOA MEX001396 Genes associated with Kinase Inhibitor Gefitinib Genes associated with Kinase Inhibitor Gefitinib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB MEX001956 Genes associated with Kinase Inhibitor 844499 71 4 Genes associated with Kinase Inhibitor 844499-71-4, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB TAX016408 GO:0006541 biological process glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. (more detail) 22 NA Homo sapiens

GOA TAX001141 Genes annotated by the GO term GO:0008094. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single or double stranded DNA; drives another reaction. (more detail) 22 NA Homo sapiens

MSigDB PEX000769 SET: SET domain SET domains are protein lysine methyltransferase enzymes. SET domains appear to be protein-protein i (more detail) 22 NA Homo sapiens

Pfam MEX001895 Genes associated with Kinase Inhibitor Motesanib Genes associated with Kinase Inhibitor Motesanib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB MEX001859 Genes associated with Kinase Inhibitor 405169 16 6 Genes associated with Kinase Inhibitor 405169-16-6, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB WIG000567 Nicotinate and nicotinamide metabolism (more detail) 22 NA Homo sapiens

MSigDB MEX001613 Genes associated with Kinase Inhibitor CHEMBL1241473 Genes associated with Kinase Inhibitor CHEMBL1241473, curated by the Drug Signature Database (DSigDB (more detail) 22 25990557 Homo sapiens

DSigDB MEX001455 Genes associated with Kinase Inhibitor CHEMBL468963 Genes associated with Kinase Inhibitor CHEMBL468963, curated by the Drug Signature Database (DSigDB) (more detail) 22 25990557 Homo sapiens

DSigDB WIG001319 Genes involved in YAP1 and WWTR1 (TAZ) stimulated gene expression (more detail) 22 NA Homo sapiens

MSigDB TAX001032 Genes annotated by the GO term GO:0030532. A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP or U4/U6 snRNP. Many, but not all, of these complexes are involved in splicing of nuclear mRNAs. (more detail) 22 NA Homo sapiens

MSigDB WAG001436 Homologous recombination Homologous recombition (HR) is essential for the accurate repair of D double-strand breaks (DSBs), p (more detail) 22 NA Homo sapiens

KEGG WIG000354 IL 2 signaling pathway Interleukin 2 (IL-2) is a potent cytokine that can lead to cellular activation and proliferation. IL (more detail) 22 NA Homo sapiens

MSigDB WIG001267 Genes involved in Termination of O glycan biosynthesis (more detail) 22 NA Homo sapiens

MSigDB WIG000470 Aminoacyl tRNA biosynthesis (more detail) 22 NA Homo sapiens

MSigDB MEX001537 Genes associated with Kinase Inhibitor NCGC00346967 01 Genes associated with Kinase Inhibitor NCGC00346967-01, curated by the Drug Signature Database (DSig (more detail) 22 25990557 Homo sapiens

DSigDB WIG000841 Genes involved in FGFR ligand binding and activation (more detail) 22 NA Homo sapiens

MSigDB WIG000528 Glycosaminoglycan biosynthesis chondroitin sulfate Glycosaminoglycans (GAGs) are linear polysaccharide chains consisting of repeating disaccharide unit (more detail) 22 NA Homo sapiens

MSigDB MEX002410 Genes associated with Kinase Inhibitor Gefitinib Genes associated with Kinase Inhibitor Gefitinib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB MEX001972 Genes associated with Kinase Inhibitor 722544 51 6 Genes associated with Kinase Inhibitor 722544-51-6, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB MEX001434 Genes associated with Kinase Inhibitor Brivanib Genes associated with Kinase Inhibitor Brivanib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB TAX016530 GO:0006688 biological process glycosphingolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with (more detail) 22 NA Homo sapiens

GOA WAG000645 erk1/erk2 mapk signaling pathway The p44/42 MAP Kise pathway consists of a protein kise cascade linking growth and differentiation si (more detail) 22 NA Homo sapiens

BioCarta WIG000758 Genes involved in Circadian Repression of Expression by REV ERBA (more detail) 22 NA Homo sapiens

MSigDB WAG001493 Abortive elongation of HIV 1 transcript in the absence of Tat (more detail) 22 NA Homo sapiens

Reactome TAX013348 GO:0000289 biological process nuclear transcribed mRNA poly(A) tail shortening Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. (more detail) 22 NA Homo sapiens

GOA WIG000888 Genes involved in GRB2 events in ERBB2 signaling (more detail) 22 NA Homo sapiens

MSigDB FOX000550 Genes in the cancer module 219 (more detail) 22 NA Homo sapiens

MSigDB FOX000560 Genes in the cancer module 233 (more detail) 22 NA Homo sapiens

MSigDB IEI003041 Protein protein interactors of human gene CSF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSF2 (SwissProt ID=P (more detail) 31 17535438 Homo sapiens

I2D IEI006389 Protein protein interactors of human gene ING3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ING3 (SwissProt ID=Q (more detail) 31 17535438 Homo sapiens

I2D MOX004260 Genes associated with Computational Drug Signature levodopa Genes associated with Computational Drug Signature levodopa, curated by the Drug Signature Database (more detail) 31 25990557 Homo sapiens

DSigDB IEI002795 Protein protein interactors of human gene COL1A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COL1A1 (SwissProt ID (more detail) 56 17535438 Homo sapiens

I2D TAX018122 GO:0010803 biological process regulation of tumor necrosis factor mediated signaling pathway Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathwa (more detail) 56 NA Homo sapiens

GOA IEI003998 Protein protein interactors of human gene EGLN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EGLN3 (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D TAX027897 GO:0060421 biological process positive regulation of heart growth Any process that increases the rate or extent of heart growth. Heart growth is the increase in size (more detail) 36 NA Homo sapiens

GOA IEI006436 Protein protein interactors of human gene INTS5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS5 (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D IEI006420 Protein protein interactors of human gene INSIG2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INSIG2 (SwissProt ID (more detail) 36 17535438 Homo sapiens

I2D IEI015239 Protein protein interactors of human gene ZC3H11A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZC3H11A (SwissProt I (more detail) 36 17535438 Homo sapiens

I2D IEI004249 Protein protein interactors of human gene ERCC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERCC2 (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D TAX001201 Genes annotated by the GO term GO:0004553. Catalysis of the hydrolysis of any O glycosyl bond. (more detail) 36 NA Homo sapiens

MSigDB WIG001078 Genes involved in PI3K events in ERBB4 signaling (more detail) 36 NA Homo sapiens

MSigDB IEI001137 Protein protein interactors of human gene ATRIP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATRIP (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D IEI006317 Protein protein interactors of human gene IL1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL1B (SwissProt ID=P (more detail) 43 17535438 Homo sapiens

I2D TAX033022 GO:1903573 biological process negative regulation of response to endoplasmic reticulum stress Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasm (more detail) 43 NA Homo sapiens

GOA IEI004581 Protein protein interactors of human gene FARSA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FARSA (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D IEI014550 Protein protein interactors of human gene UBA6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBA6 (SwissProt ID=A (more detail) 43 17535438 Homo sapiens

I2D TAX016978 GO:0007595 biological process lactation The regulated release of milk from the mammary glands and the period of time that a mother lactates (more detail) 43 NA Homo sapiens

GOA IEI003931 Protein protein interactors of human gene EDC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EDC4 (SwissProt ID=Q (more detail) 43 17535438 Homo sapiens

I2D WIG000270 Bioactive Peptide Induced Signaling Pathway Many different peptides act as signaling molecules, including the proinflammatory peptide bradykinin (more detail) 43 NA Homo sapiens

MSigDB TAX031677 GO:0140013 biological process meiotic nuclear division One of the two nuclear divisions that occur as part of the meiotic cell cycle. (more detail) 58 NA Homo sapiens

GOA IEI005511 Protein protein interactors of human gene GRIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRIP1 (SwissProt ID= (more detail) 58 17535438 Homo sapiens

I2D MOX002124 Genes associated with Computational Drug Signature Caffeic acid phenethyl ester Genes associated with Computational Drug Signature Caffeic acid phenethyl ester, curated by the Drug (more detail) 58 25990557 Homo sapiens

DSigDB WIG000343 HIV I Nef: negative effector of Fas and TNF HIV infection leads to drastic declines in CD4 T helper cells, in part through apoptosis of uninfect (more detail) 58 NA Homo sapiens

MSigDB IEI015836 Protein protein interactors of human gene ZRANB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZRANB2 (SwissProt ID (more detail) 60 17535438 Homo sapiens

I2D TAX022717 GO:0035066 biological process positive regulation of histone acetylation Any process that activates or increases the frequency, rate or extent of the addition of an acetyl g (more detail) 28 NA Homo sapiens

GOA IEI005900 Protein protein interactors of human gene HMGA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMGA2 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI009040 Protein protein interactors of human gene NR5A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR5A2 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI007469 Protein protein interactors of human gene LSM12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSM12 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D TAX027771 GO:0060260 biological process regulation of transcription initiation from RNA polymerase II promoter Any process that modulates the rate, frequency or extent of a process involved in starting transcrip (more detail) 28 NA Homo sapiens

GOA IEI000863 Protein protein interactors of human gene ARID4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARID4A (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D TAX001408 Genes annotated by the GO term GO:0008146. Catalysis of the transfer of a sulfate group from 3' phosphoadenosine 5' phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3' phosphoadenosine 5' phosphate. (more detail) 28 NA Homo sapiens

MSigDB MOX013656 Genes associated with Computational Drug Signature methotrexate Genes associated with Computational Drug Signature methotrexate, curated by the Drug Signature Datab (more detail) 28 25990557 Homo sapiens

DSigDB WIG001202 Genes involved in Signaling by FGFR1 mutants (more detail) 28 NA Homo sapiens

MSigDB MOX004549 Genes associated with Computational Drug Signature podophyllotoxin Genes associated with Computational Drug Signature podophyllotoxin, curated by the Drug Signature Da (more detail) 28 25990557 Homo sapiens

DSigDB FOX000543 Genes in the cancer module 210 (more detail) 28 NA Homo sapiens

MSigDB TAX013495 GO:0000791 cellular component euchromatin A dispersed and relatively uncompacted form of chromatin. (more detail) 28 NA Homo sapiens

GOA IEI003549 Protein protein interactors of human gene DHX8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHX8 (SwissProt ID=Q (more detail) 45 17535438 Homo sapiens

I2D IEI010189 Protein protein interactors of human gene POLA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLA2 (SwissProt ID= (more detail) 45 17535438 Homo sapiens

I2D IEI001205 Protein protein interactors of human gene BABAM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BABAM2 (SwissProt ID (more detail) 45 17535438 Homo sapiens

I2D WIG000441 T Cell Receptor Signaling Pathway The T Cell Receptor plays a key role in the immune system. The specificity of the receptor is govern (more detail) 45 NA Homo sapiens

MSigDB TAX016125 GO:0006094 biological process gluconeogenesis The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol (more detail) 45 NA Homo sapiens

GOA FEX000526 Breast Larsson07 76genes Supplementary table 7.Translationally regulated ribosomal genes. (more detail) 45 17638893 Homo sapiens

GeneSigDB WAG000192 Endometrial cancer Endometrial cancer (EC) is the most common gyecological maligncy and the fourth most common maligncy (more detail) 45 NA Homo sapiens

KEGG IEI007572 Protein protein interactors of human gene MAFF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAFF (SwissProt ID=Q (more detail) 25 17535438 Homo sapiens

I2D IEI014035 Protein protein interactors of human gene TNIP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNIP2 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI001475 Protein protein interactors of human gene BTG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BTG1 (SwissProt ID=P (more detail) 25 17535438 Homo sapiens

I2D TAX025629 GO:0046540 cellular component U4/U6 x U5 tri snRNP complex A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleopr (more detail) 25 NA Homo sapiens

GOA WAG001239 influence of ras and rho proteins on g1 to s transition The cell cycle transition from G1 to S phase is a key regulatory point in the cell cycle. This tran (more detail) 25 NA Homo sapiens

BioCarta TAX013221 GO:0000030 molecular function mannosyltransferase activity Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrat (more detail) 25 NA Homo sapiens

GOA TAX000446 Genes annotated by the GO term GO:0006730. The chemical reactions and pathways involving compounds containing a single carbon atom. (more detail) 25 NA Homo sapiens

MSigDB TAX001049 Genes annotated by the GO term GO:0000151. A protein complex that includes a ubiquitin protein ligase (E3) and other proteins that may confer substrate specificity on the complex. (more detail) 25 NA Homo sapiens

MSigDB WIG000558 Maturity onset diabetes of the young About 2-5% of type II diabetic patients suffer from a monogenic disease with autosomal dominant inhe (more detail) 25 NA Homo sapiens

MSigDB IEI001441 Protein protein interactors of human gene BRIX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRIX1 (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D IEI010638 Protein protein interactors of human gene PSMB9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMB9 (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D WIG000633 Tryptophan metabolism (more detail) 38 NA Homo sapiens

MSigDB WIG000058 ErbB4 signaling events (more detail) 38 NA Homo sapiens

MSigDB WIG000132 Signaling mediated by p38 alpha and p38 beta (more detail) 38 NA Homo sapiens

MSigDB IEI001782 Protein protein interactors of human gene CAPRIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAPRIN1 (SwissProt I (more detail) 47 17535438 Homo sapiens

I2D IEI010489 Protein protein interactors of human gene PRKCQ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRKCQ (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D IEI003958 Protein protein interactors of human gene EEF2K from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EEF2K (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D IEI004331 Protein protein interactors of human gene ETV6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ETV6 (SwissProt ID=P (more detail) 33 17535438 Homo sapiens

I2D IEI011474 Protein protein interactors of human gene RORA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RORA (SwissProt ID=P (more detail) 33 17535438 Homo sapiens

I2D WEX000047 Immortality & Stemness The genes related to immortality & stemness (cell function) in tumor using next-generation sequencer (more detail) 33 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas FOX000139 Neighborhood of G22P1 Neighborhood of G22P1 NULL in the GNF2 expression compendium (more detail) 33 NA Homo sapiens

MSigDB WAG000191 Alzheimer's disease Alzheimer's disease (AD) is a chronic disorder that slowly destroys neurons and causes serious cogni (more detail) 49 NA Homo sapiens

KEGG TAX021385 GO:0032206 biological process positive regulation of telomere maintenance Any process that activates or increases the frequency, rate or extent of a process that affects and (more detail) 49 NA Homo sapiens

GOA FAX003041 GSEA Hallmark Pancreatic Cancer Tissue Explants (Extracellular Vesicles) Coagulation Top 3 pathways enriched in pancreatic cancer tissue extract extracellular vesicle particles compared (more detail) 49 32795414 Homo sapiens

Cell WEX000016 Complement System The genes related to complement system (innate immunity) in immune using next-generation sequencer ( (more detail) 49 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI014624 Protein protein interactors of human gene UBR4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBR4 (SwissProt ID=Q (more detail) 49 17535438 Homo sapiens

I2D IEI014976 Protein protein interactors of human gene WBP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WBP4 (SwissProt ID=O (more detail) 49 17535438 Homo sapiens

I2D IEI002041 Protein protein interactors of human gene CCND3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCND3 (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D FOX000843 Genes in the cancer module 85 (more detail) 51 NA Homo sapiens

MSigDB FEX010795 hsa miR 491 3p HITS-CLIP, Functional MTI (Weak) (more detail) 51 NA Homo sapiens

mirTARbase IEI003555 Protein protein interactors of human gene DICER1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DICER1 (SwissProt ID (more detail) 51 17535438 Homo sapiens

I2D IEI013737 Protein protein interactors of human gene TIRAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TIRAP (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D IEI010211 Protein protein interactors of human gene POLR1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR1B (SwissProt ID (more detail) 40 17535438 Homo sapiens

I2D IEI014673 Protein protein interactors of human gene UHRF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UHRF1 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D IEI004582 Protein protein interactors of human gene FARSB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FARSB (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D TAX020650 GO:0030811 biological process regulation of nucleotide catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 40 NA Homo sapiens

GOA IEI006093 Protein protein interactors of human gene HTATSF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HTATSF1 (SwissProt I (more detail) 40 17535438 Homo sapiens

I2D MAX000955 Down regulated genes in colon carcinoma tumors with lymph node metastases. To characterize patterns of global transcriptional deregulation in primary colon carcinomas, we did (more detail) 40 NA Homo sapiens

MSigDB MOX001841 Genes associated with Computational Drug Signature cilostazol Genes associated with Computational Drug Signature cilostazol, curated by the Drug Signature Databas (more detail) 40 25990557 Homo sapiens

DSigDB WAG000390 Alanine and aspartate metabolism (more detail) 40 NA Homo sapiens

KEGG WIG001514 G1 S Phase Transition G1-S Phase Transition (more detail) 40 NA Homo sapiens

Protein Lounge IEI011418 Protein protein interactors of human gene RNF185 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF185 (SwissProt ID (more detail) 53 17535438 Homo sapiens

I2D IEI000462 Protein protein interactors of human gene ALDH18A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ALDH18A1 (SwissProt (more detail) 53 17535438 Homo sapiens

I2D IEI004227 Protein protein interactors of human gene EPPK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPPK1 (SwissProt ID= (more detail) 53 17535438 Homo sapiens

I2D MAX001707 Genes down regulated in fibroblasts from old individuals, compared to those from young donors. Messenger RNA levels were measured in actively dividing fibroblasts isolated from young, middle-age, (more detail) 53 NA Homo sapiens

MSigDB MAX002044 Genes up regulated in MCF7 cells (breast cancer) after stimulation with EGF [GeneID=1950]. ErbB receptor ligands, epidermal growth factor (EGF) and heregulin (HRG), induce dose-dependent tran (more detail) 55 NA Homo sapiens

MSigDB FOX000136 Neighborhood of FEN1 Neighborhood of FEN1 flap structure-specific endonuclease 1 in the GNF2 expression compendium (more detail) 55 NA Homo sapiens

MSigDB IEI005595 Protein protein interactors of human gene GTF3C4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF3C4 (SwissProt ID (more detail) 55 17535438 Homo sapiens

I2D TAX019118 GO:0016597 molecular function amino acid binding Interacting selectively and non-covalently with an amino acid, organic acids containing one or more (more detail) 55 NA Homo sapiens

GOA IEI005551 Protein protein interactors of human gene GSN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GSN (SwissProt ID=P0 (more detail) 55 17535438 Homo sapiens

I2D IEI001775 Protein protein interactors of human gene CAPN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAPN2 (SwissProt ID= (more detail) 55 17535438 Homo sapiens

I2D IEI008020 Protein protein interactors of human gene MKRN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MKRN3 (SwissProt ID= (more detail) 57 17535438 Homo sapiens

I2D IEI002133 Protein protein interactors of human gene CD40 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CD40 (SwissProt ID=P (more detail) 57 17535438 Homo sapiens

I2D MOX014955 Genes associated with Computational Drug Signature Salazinic acid Genes associated with Computational Drug Signature Salazinic acid, curated by the Drug Signature Dat (more detail) 57 25990557 Homo sapiens

DSigDB WAG000378 Tyrosine metabolism (more detail) 57 NA Homo sapiens

KEGG IEI001402 Protein protein interactors of human gene BOP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BOP1 (SwissProt ID=Q (more detail) 42 17535438 Homo sapiens

I2D IEI011532 Protein protein interactors of human gene RPL35A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL35A (SwissProt ID (more detail) 42 17535438 Homo sapiens

I2D FEX001334 Leukemia Passioura05 43genes Table S4 ? Genes down-regulated by N-rasG13R in U937 cells (more detail) 42 15705876 Homo sapiens

GeneSigDB IEI002310 Protein protein interactors of human gene CEBPZ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CEBPZ (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D IEI007803 Protein protein interactors of human gene MCMBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCMBP (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D IEI014687 Protein protein interactors of human gene UMPS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UMPS (SwissProt ID=P (more detail) 30 17535438 Homo sapiens

I2D IEI006814 Protein protein interactors of human gene KIF11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIF11 (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D MOX017198 Genes associated with Computational Drug Signature Carfilzomib Genes associated with Computational Drug Signature Carfilzomib, curated by the Drug Signature Databa (more detail) 30 25990557 Homo sapiens

DSigDB FOX000140 Neighborhood of GLTSCR2 Neighborhood of GLTSCR2 glioma tumor suppressor candidate region gene 2 in the GNF2 expression comp (more detail) 30 NA Homo sapiens

MSigDB WIG001803 ABCG and ABCA Regulation of Sterol Metabolism ABCG and ABCA Regulation of Sterol Metabolism (more detail) 30 NA Homo sapiens

Protein Lounge MEX002386 Genes associated with Kinase Inhibitor GW843682X Genes associated with Kinase Inhibitor GW843682X, curated by the Drug Signature Database (DSigDB). (more detail) 30 25990557 Homo sapiens

DSigDB PEX002137 Bromodomain: Bromodomain Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. (more detail) 30 NA Homo sapiens

Pfam MEX000535 Genes associated with Approved Drug daunorubicin Genes associated with Approved Drug daunorubicin, curated by the Drug Signature Database (DSigDB). (more detail) 30 25990557 Homo sapiens

DSigDB MOX003788 Genes associated with Computational Drug Signature cantharidin Genes associated with Computational Drug Signature cantharidin, curated by the Drug Signature Databa (more detail) 35 25990557 Homo sapiens

DSigDB MOX001392 Genes associated with Computational Drug Signature Tauroursodeoxycholic acid Genes associated with Computational Drug Signature Tauroursodeoxycholic acid, curated by the Drug Si (more detail) 35 25990557 Homo sapiens

DSigDB WAG001246 toll like receptor pathway The inte immune response responds in a general manner to factors present in invading pathogens. Bact (more detail) 35 NA Homo sapiens

BioCarta MOX014382 Genes associated with Computational Drug Signature PD 98059 Genes associated with Computational Drug Signature PD 98059, curated by the Drug Signature Database (more detail) 35 25990557 Homo sapiens

DSigDB MOX014620 Genes associated with Computational Drug Signature progesterone Genes associated with Computational Drug Signature progesterone, curated by the Drug Signature Datab (more detail) 35 25990557 Homo sapiens

DSigDB TAX017389 GO:0008649 molecular function rRNA methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in (more detail) 21 NA Homo sapiens

GOA IEI010228 Protein protein interactors of human gene POLR2K from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2K (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D TAX021380 GO:0032201 biological process telomere maintenance via semi conservative replication The process in which telomeric DNA is synthesized semi-conservatively by the conventional replicatio (more detail) 21 NA Homo sapiens

GOA TAX034925 GO:2000781 biological process positive regulation of double strand break repair Any process that activates or increases the frequency, rate or extent of double-strand break repair. (more detail) 21 NA Homo sapiens

GOA TAX022794 GO:0035268 biological process protein mannosylation The addition of a mannose residue to a protein acceptor molecule. (more detail) 21 NA Homo sapiens

GOA TAX025468 GO:0046132 biological process pyrimidine ribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside i (more detail) 21 NA Homo sapiens

GOA TAX017493 GO:0009081 biological process branched chain amino acid metabolic process The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, com (more detail) 21 NA Homo sapiens

GOA IEI005481 Protein protein interactors of human gene GRB14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRB14 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D TAX023849 GO:0042454 biological process ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside i (more detail) 21 NA Homo sapiens

GOA TAX028680 GO:0070003 molecular function threonine type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydr (more detail) 21 NA Homo sapiens

GOA TAX015868 GO:0005680 cellular component anaphase promoting complex A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby tr (more detail) 21 NA Homo sapiens

GOA IEI004091 Protein protein interactors of human gene ELL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELL (SwissProt ID=P5 (more detail) 21 17535438 Homo sapiens

I2D IEI002272 Protein protein interactors of human gene CDKN1C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDKN1C (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D TAX017983 GO:0010586 biological process miRNA metabolic process The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecu (more detail) 21 NA Homo sapiens

GOA TAX023814 GO:0042401 biological process cellular biogenic amine biosynthetic process The chemical reactions and pathways occurring at the level of individual cells resulting in the form (more detail) 21 NA Homo sapiens

GOA TAX019088 GO:0016556 biological process mRNA modification The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecu (more detail) 21 NA Homo sapiens

GOA IEI005248 Protein protein interactors of human gene GLI3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLI3 (SwissProt ID=P (more detail) 21 17535438 Homo sapiens

I2D IEI003315 Protein protein interactors of human gene DBF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DBF4 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D TAX031708 GO:0140102 molecular function catalytic activity, acting on a rRNA Catalytic activity that acts to modify a ribosomal RNA. (more detail) 21 NA Homo sapiens

GOA WIG000673 Genes involved in Acyl chain remodelling of PC (more detail) 21 NA Homo sapiens

MSigDB MEX002324 Genes associated with Kinase Inhibitor CHEMBL1967116 Genes associated with Kinase Inhibitor CHEMBL1967116, curated by the Drug Signature Database (DSigDB (more detail) 21 25990557 Homo sapiens

DSigDB WIG000347 IGF 1 Signaling Pathway Insulin like growth factor 1 (IGF-1) and its receptor (IGF-1R) provide a potent proliferative signal (more detail) 21 NA Homo sapiens

MSigDB MEX001652 Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens

DSigDB TAX001138 Genes annotated by the GO term GO:0004536. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. (more detail) 21 NA Homo sapiens

MSigDB WAG000383 Chondroitin sulfate biosynthesis Glycosaminoglycans (GAGs) are linear polysaccharide chains consisting of repeating disaccharide unit (more detail) 21 NA Homo sapiens

KEGG TAX015035 GO:0004198 molecular function calcium dependent cysteine type endopeptidase activity Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using (more detail) 21 NA Homo sapiens

GOA TAX013469 GO:0000729 biological process DNA double strand break processing The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand (more detail) 21 NA Homo sapiens

GOA MEX002120 Genes associated with Kinase Inhibitor GW559768X Genes associated with Kinase Inhibitor GW559768X, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens

DSigDB MEX001818 Genes associated with Kinase Inhibitor TPCA 1 Genes associated with Kinase Inhibitor TPCA-1, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens

DSigDB WAG000204 Mismatch repair D mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintainin (more detail) 21 NA Homo sapiens

KEGG WAG000644 role of brca1 brca2 and atr in cancer susceptibility BRCA1 and BRCA2 were identified genetically as breast cancer susceptibility genes when a single copy (more detail) 21 NA Homo sapiens

BioCarta FEX001576 Leukemia Sanchez Guijo08 22genes SuppTable2b Genes involved in transcription (more detail) 21 18722011 Homo sapiens

GeneSigDB TAX016174 GO:0006182 biological process cGMP biosynthetic process The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosph (more detail) 21 NA Homo sapiens

GOA TAX001016 Genes annotated by the GO term GO:0000502. A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. (more detail) 21 NA Homo sapiens

MSigDB FOX000814 Genes in the cancer module 58 (more detail) 21 NA Homo sapiens

MSigDB FEX002683 Prostate Scharer09 23genes Table 2. DAVID analysis identified 23 transcription factors present in our high confidence SOX4 targ (more detail) 21 19147588 Homo sapiens

GeneSigDB MOX007316 Genes associated with Computational Drug Signature bisindolylmaleimide IX Genes associated with Computational Drug Signature bisindolylmaleimide IX, curated by the Drug Signa (more detail) 21 25990557 Homo sapiens

DSigDB MAX002119 Genes within amplicon 19q13.1 identified in a copy number alterations study of 191 breast tumor samples. A single cancer cell contains large numbers of genetic alterations that in combination create the ma (more detail) 21 NA Homo sapiens

MSigDB FEX001568 Leukemia Andreeff08 21genes Supplementary Table 4 Genes differently expressed in AMLs with NPM mutations (more detail) 21 18668134 Homo sapiens

GeneSigDB TAX016236 GO:0006293 biological process nucleotide excision repair, preincision complex stabilization The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, a (more detail) 21 NA Homo sapiens

GOA WAG000808 RNA polymerase (more detail) 21 NA Homo sapiens

KEGG TAX001134 Genes annotated by the GO term GO:0003684. Interacting selectively with damaged DNA. (more detail) 21 NA Homo sapiens

MSigDB TAX000184 Genes annotated by the GO term GO:0006302. The repair of double strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. (more detail) 21 NA Homo sapiens

MSigDB TAX015038 GO:0004298 molecular function threonine type endopeptidase activity Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which (more detail) 21 NA Homo sapiens

GOA IEI004571 Protein protein interactors of human gene FANCI from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FANCI (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D MOX005099 Genes associated with Computational Drug Signature nelfinavir Genes associated with Computational Drug Signature nelfinavir, curated by the Drug Signature Databas (more detail) 44 25990557 Homo sapiens

DSigDB FEX001981 Lung Mikkonen10 72genes Table S6b: Enrichment of gene ontology (GO) categories for down-regulated genes in A549 cells upon T (more detail) 44 20035825 Homo sapiens

GeneSigDB IEI006228 Protein protein interactors of human gene IGF2BP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGF2BP2 (SwissProt I (more detail) 44 17535438 Homo sapiens

I2D IEI007806 Protein protein interactors of human gene MCPH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCPH1 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D TAX034924 GO:2000780 biological process negative regulation of double strand break repair Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break rep (more detail) 27 NA Homo sapiens

GOA IEI008803 Protein protein interactors of human gene NFRKB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFRKB (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D TAX022387 GO:0034243 biological process regulation of transcription elongation from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription elongation, the extension (more detail) 27 NA Homo sapiens

GOA IEI015292 Protein protein interactors of human gene ZEB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZEB2 (SwissProt ID=O (more detail) 27 17535438 Homo sapiens

I2D IEI001235 Protein protein interactors of human gene BATF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BATF (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D MOX003517 Genes associated with Computational Drug Signature Carfilzomib Genes associated with Computational Drug Signature Carfilzomib, curated by the Drug Signature Databa (more detail) 27 25990557 Homo sapiens

DSigDB MOX003988 Genes associated with Computational Drug Signature iodoquinol Genes associated with Computational Drug Signature iodoquinol, curated by the Drug Signature Databas (more detail) 27 25990557 Homo sapiens

DSigDB TAX000258 Genes annotated by the GO term GO:0046483. The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). (more detail) 27 NA Homo sapiens

MSigDB TAX000043 Genes annotated by the GO term GO:0006725. The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons. (more detail) 27 NA Homo sapiens

MSigDB MOX000135 Genes associated with Computational Drug Signature p benzoquinone Genes associated with Computational Drug Signature p-benzoquinone, curated by the Drug Signature Dat (more detail) 46 25990557 Homo sapiens

DSigDB FOX000584 Genes in the cancer module 259 (more detail) 46 NA Homo sapiens

MSigDB MOX001490 Genes associated with Computational Drug Signature catechol Genes associated with Computational Drug Signature catechol, curated by the Drug Signature Database (more detail) 46 25990557 Homo sapiens

DSigDB TAX021689 GO:0032648 biological process regulation of interferon beta production Any process that modulates the frequency, rate, or extent of interferon-beta production. (more detail) 46 NA Homo sapiens

GOA WIG001940 Notch Signaling Pathway Notch Signaling Pathway (more detail) 46 NA Homo sapiens

WikiPathway MOX005116 Genes associated with Computational Drug Signature butyric acid Genes associated with Computational Drug Signature butyric acid, curated by the Drug Signature Datab (more detail) 46 25990557 Homo sapiens

DSigDB IEI014993 Protein protein interactors of human gene WDR26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR26 (SwissProt ID= (more detail) 46 17535438 Homo sapiens

I2D IEI000960 Protein protein interactors of human gene ASB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASB2 (SwissProt ID=Q (more detail) 37 17535438 Homo sapiens

I2D IEI014298 Protein protein interactors of human gene TRMT112 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRMT112 (SwissProt I (more detail) 37 17535438 Homo sapiens

I2D IEI005287 Protein protein interactors of human gene GMNN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GMNN (SwissProt ID=O (more detail) 37 17535438 Homo sapiens

I2D IEI011387 Protein protein interactors of human gene RNF126 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF126 (SwissProt ID (more detail) 37 17535438 Homo sapiens

I2D IEI012598 Protein protein interactors of human gene SMARCD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCD2 (SwissProt I (more detail) 37 17535438 Homo sapiens

I2D IEI014285 Protein protein interactors of human gene TRIP12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIP12 (SwissProt ID (more detail) 37 17535438 Homo sapiens

I2D IEI005838 Protein protein interactors of human gene HIF1AN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HIF1AN (SwissProt ID (more detail) 37 17535438 Homo sapiens

I2D IEI007276 Protein protein interactors of human gene LIMK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LIMK1 (SwissProt ID= (more detail) 37 17535438 Homo sapiens

I2D TAX013388 GO:0000387 biological process spliceosomal snRNP assembly The aggregation, arrangement and bonding together of one or more snRNA and multiple protein componen (more detail) 37 NA Homo sapiens

GOA WIG000452 Toll Like Receptor Pathway The innate immune response responds in a general manner to factors present in invading pathogens. Ba (more detail) 37 NA Homo sapiens

MSigDB TAX024076 GO:0042974 molecular function retinoic acid receptor binding Interacting selectively and non-covalently with the retinoic acid receptor, a ligand-regulated trans (more detail) 24 NA Homo sapiens

GOA TAX023198 GO:0036003 biological process positive regulation of transcription from RNA polymerase II promoter in response to stress Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II (more detail) 24 NA Homo sapiens

GOA TAX021778 GO:0032786 biological process positive regulation of DNA templated transcription, elongation Any process that activates or increases the frequency, rate or extent of transcription elongation, t (more detail) 24 NA Homo sapiens

GOA TAX017824 GO:0009975 molecular function cyclase activity Catalysis of a ring closure reaction. (more detail) 24 NA Homo sapiens

GOA IEI007849 Protein protein interactors of human gene MED20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED20 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D TAX027634 GO:0060045 biological process positive regulation of cardiac muscle cell proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell prolife (more detail) 24 NA Homo sapiens

GOA IEI009646 Protein protein interactors of human gene PDCD11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDCD11 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D IEI009336 Protein protein interactors of human gene ORC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ORC6 (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D WAG000651 p38 mapk signaling pathway p38 MAPKs are members of the MAPK family that are activated by a variety of environmental stresses a (more detail) 24 NA Homo sapiens

BioCarta WAG001014 pdgf signaling pathway Platelet Derived Growth Factor (PDGF) plays a critical role in cellular proliferation and developmen (more detail) 24 NA Homo sapiens

BioCarta MOX001029 Genes associated with Computational Drug Signature Cryptolepine Genes associated with Computational Drug Signature Cryptolepine, curated by the Drug Signature Datab (more detail) 24 25990557 Homo sapiens

DSigDB WIG001575 Intrinsic Prothrombin Activation Pathway Intrinsic Prothrombin Activation Pathway (more detail) 24 NA Homo sapiens

Protein Lounge WIG000664 Genes involved in Activation of Genes by ATF4 (more detail) 24 NA Homo sapiens

MSigDB FOX000840 Genes in the cancer module 82 (more detail) 24 NA Homo sapiens

MSigDB WIG001176 Genes involved in RNA Polymerase I Transcription Initiation (more detail) 24 NA Homo sapiens

MSigDB WIG001035 Genes involved in Nuclear Events (kinase and transcription factor activation) (more detail) 24 NA Homo sapiens

MSigDB TAX035068 GO:2001169 biological process regulation of ATP biosynthetic process Any process that modulates the frequency, rate or extent of ATP biosynthetic process. (more detail) 48 NA Homo sapiens

GOA IEI008781 Protein protein interactors of human gene NFATC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFATC2 (SwissProt ID (more detail) 48 17535438 Homo sapiens

I2D TAX025256 GO:0045747 biological process positive regulation of Notch signaling pathway Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway (more detail) 48 NA Homo sapiens

GOA IEI005798 Protein protein interactors of human gene HERC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HERC2 (SwissProt ID= (more detail) 48 17535438 Homo sapiens

I2D IEI014693 Protein protein interactors of human gene UNC45A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UNC45A (SwissProt ID (more detail) 48 17535438 Homo sapiens

I2D TAX000334 Genes annotated by the GO term GO:0046467. The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane. (more detail) 48 NA Homo sapiens

MSigDB WAG001264 TGF beta receptor signaling (more detail) 48 NA Homo sapiens

NCI-Nature Curated TAX013497 GO:0000793 cellular component condensed chromosome A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct str (more detail) 48 NA Homo sapiens

GOA IEI003198 Protein protein interactors of human gene CXXC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CXXC1 (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D IEI009334 Protein protein interactors of human gene ORC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ORC4 (SwissProt ID=O (more detail) 32 17535438 Homo sapiens

I2D IEI004657 Protein protein interactors of human gene FBXO5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO5 (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D TAX027537 GO:0055023 biological process positive regulation of cardiac muscle tissue growth Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle g (more detail) 32 NA Homo sapiens

GOA IEI009333 Protein protein interactors of human gene ORC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ORC3 (SwissProt ID=Q (more detail) 32 17535438 Homo sapiens

I2D IEI001297 Protein protein interactors of human gene BCOR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCOR (SwissProt ID=Q (more detail) 32 17535438 Homo sapiens

I2D WIG000080 HIF 2 alpha transcription factor network (more detail) 32 NA Homo sapiens

MSigDB WIG000843 Genes involved in Formation of Fibrin Clot (Clotting Cascade) (more detail) 32 NA Homo sapiens

MSigDB IEI006387 Protein protein interactors of human gene ING1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ING1 (SwissProt ID=Q (more detail) 50 17535438 Homo sapiens

I2D FOX000143 Neighborhood of HAT1 Neighborhood of HAT1 histone acetyltransferase 1 in the GNF2 expression compendium (more detail) 50 NA Homo sapiens

MSigDB MOX003306 Genes associated with Computational Drug Signature INDIRUBIN 3' MONOXIME Genes associated with Computational Drug Signature INDIRUBIN-3'-MONOXIME, curated by the Drug Signat (more detail) 52 25990557 Homo sapiens

DSigDB MAX003220 Up regulated genes distinguishing hepatocellular carcinoma (HCC) samples positive for EPCAM [GeneID=4072] from the negative ones. The heterogeneous nature of hepatocellular carcinoma (HCC) and the lack of appropriate biomarkers ha (more detail) 52 NA Homo sapiens

MSigDB MOX004301 Genes associated with Computational Drug Signature Melitten Genes associated with Computational Drug Signature Melitten, curated by the Drug Signature Database (more detail) 52 25990557 Homo sapiens

DSigDB IEI010779 Protein protein interactors of human gene PURA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PURA (SwissProt ID=Q (more detail) 39 17535438 Homo sapiens

I2D IEI002253 Protein protein interactors of human gene CDK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK3 (SwissProt ID=Q (more detail) 39 17535438 Homo sapiens

I2D WIG000323 Fc Epsilon Receptor I Signaling in Mast Cells The Fc Epsilon Receptor 1 signaling pathway in mast cells uses multiple core signal path to achieve (more detail) 39 NA Homo sapiens

MSigDB TAX016139 GO:0006110 biological process regulation of glycolytic process Any process that modulates the frequency, rate or extent of glycolysis. (more detail) 39 NA Homo sapiens

GOA WAG001046 p75(NTR) mediated signaling (more detail) 54 NA Homo sapiens

NCI-Nature Curated TAX019244 GO:0016830 molecular function carbon carbon lyase activity Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely (more detail) 54 NA Homo sapiens

GOA IEI009342 Protein protein interactors of human gene OS9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OS9 (SwissProt ID=Q1 (more detail) 54 17535438 Homo sapiens

I2D IEI013598 Protein protein interactors of human gene TFAP2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TFAP2A (SwissProt ID (more detail) 54 17535438 Homo sapiens

I2D IEI004766 Protein protein interactors of human gene FHL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FHL1 (SwissProt ID=Q (more detail) 54 17535438 Homo sapiens

I2D TAX025707 GO:0046686 biological process response to cadmium ion Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 54 NA Homo sapiens

GOA TAX022528 GO:0034502 biological process protein localization to chromosome Any process in which a protein is transported to, or maintained at, a specific location on a chromos (more detail) 54 NA Homo sapiens

GOA IEI001042 Protein protein interactors of human gene ATIC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATIC (SwissProt ID=P (more detail) 56 17535438 Homo sapiens

I2D WAG001611 Renal cell carcinoma Rel cell cancer (RCC) accounts for ~3% of human maligncies and its incidence appears to be rising. A (more detail) 56 NA Homo sapiens

KEGG IEI011395 Protein protein interactors of human gene RNF14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF14 (SwissProt ID= (more detail) 41 17535438 Homo sapiens

I2D IEI011787 Protein protein interactors of human gene SAP30 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SAP30 (SwissProt ID= (more detail) 41 17535438 Homo sapiens

I2D MAX002316 Top marker genes in medulloblastoma associated with poor response to treatment (poor outcome). Embryonal tumours of the central nervous system (CNS) represent a heterogeneous group of tumours abo (more detail) 41 NA Homo sapiens

MSigDB WIG001718 UVA Induced MAPK Signaling UVA-Induced MAPK Signaling (more detail) 41 NA Homo sapiens

Protein Lounge WIG001695 Apoptotic Pathways Triggered By HIV1 Apoptotic Pathways Triggered By HIV1 (more detail) 41 NA Homo sapiens

Protein Lounge WAG001446 beta Alanine metabolism (more detail) 41 NA Homo sapiens

KEGG TAX024925 GO:0045070 biological process positive regulation of viral genome replication Any process that activates or increases the frequency, rate or extent of viral genome replication. (more detail) 34 NA Homo sapiens

GOA IEI011344 Protein protein interactors of human gene RLIM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RLIM (SwissProt ID=Q (more detail) 34 17535438 Homo sapiens

I2D IEI009551 Protein protein interactors of human gene PCBD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCBD2 (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D IEI013499 Protein protein interactors of human gene TCF7L2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCF7L2 (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D IEI008866 Protein protein interactors of human gene NKX3 1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NKX3-1 (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D TAX030526 GO:0090398 biological process cellular senescence A cell aging process stimulated in response to cellular stress, whereby normal cells lose the abilit (more detail) 29 NA Homo sapiens

GOA TAX026520 GO:0050686 biological process negative regulation of mRNA processing Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing. (more detail) 29 NA Homo sapiens

GOA IEI011005 Protein protein interactors of human gene RARB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RARB (SwissProt ID=P (more detail) 29 17535438 Homo sapiens

I2D IEI012773 Protein protein interactors of human gene SOX10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOX10 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI013347 Protein protein interactors of human gene TAF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF2 (SwissProt ID=Q (more detail) 29 17535438 Homo sapiens

I2D TAX024019 GO:0042788 cellular component polysomal ribosome A ribosome bound to mRNA that forms part of a polysome. (more detail) 29 NA Homo sapiens

GOA MOX012176 Genes associated with Computational Drug Signature daunorubicin Genes associated with Computational Drug Signature daunorubicin, curated by the Drug Signature Datab (more detail) 29 25990557 Homo sapiens

DSigDB WIG001719 UVB Induced MAPK Signaling UVB-Induced MAPK Signaling (more detail) 29 NA Homo sapiens

Protein Lounge WIG000767 Genes involved in Complement cascade (more detail) 29 NA Homo sapiens

MSigDB IEI003791 Protein protein interactors of human gene DROSHA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DROSHA (SwissProt ID (more detail) 43 17535438 Homo sapiens

I2D IEI005145 Protein protein interactors of human gene GEMIN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GEMIN2 (SwissProt ID (more detail) 43 17535438 Homo sapiens

I2D WIG000176 Signaling events mediated by TCPTP (more detail) 43 NA Homo sapiens

MSigDB MOX000767 Genes associated with Computational Drug Signature Bromoacetate Genes associated with Computational Drug Signature Bromoacetate, curated by the Drug Signature Datab (more detail) 43 25990557 Homo sapiens

DSigDB TAX025549 GO:0046386 biological process deoxyribose phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phospho (more detail) 20 NA Homo sapiens

GOA TAX025454 GO:0046112 biological process nucleobase biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base t (more detail) 20 NA Homo sapiens

GOA TAX025692 GO:0046653 biological process tetrahydrofolate metabolic process The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a fola (more detail) 20 NA Homo sapiens

GOA TAX023286 GO:0036150 biological process phosphatidylserine acyl chain remodeling Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation re (more detail) 20 NA Homo sapiens

GOA TAX020193 GO:0022616 biological process DNA strand elongation The DNA metabolic process in which a DNA strand is synthesized by adding nucleotides to the 3' end o (more detail) 20 NA Homo sapiens

GOA TAX021055 GO:0031572 biological process G2 DNA damage checkpoint A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the (more detail) 20 NA Homo sapiens

GOA TAX017225 GO:0008373 molecular function sialyltransferase activity Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of (more detail) 20 NA Homo sapiens

GOA TAX029192 GO:0070932 biological process histone H3 deacetylation The modification of histone H3 by the removal of one or more acetyl groups. (more detail) 20 NA Homo sapiens

GOA TAX016593 GO:0006783 biological process heme biosynthetic process The chemical reactions and pathways resulting in the formation of heme, any compound of iron complex (more detail) 20 NA Homo sapiens

GOA TAX016370 GO:0006491 biological process N glycan processing The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosacc (more detail) 20 NA Homo sapiens

GOA IEI012930 Protein protein interactors of human gene SPSB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPSB1 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI002964 Protein protein interactors of human gene CRBN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CRBN (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI004615 Protein protein interactors of human gene FBXL15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXL15 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D TAX020902 GO:0031293 biological process membrane protein intracellular domain proteolysis The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domai (more detail) 20 NA Homo sapiens

GOA TAX024131 GO:0043046 biological process DNA methylation involved in gamete generation The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of (more detail) 20 NA Homo sapiens

GOA TAX016780 GO:0007095 biological process mitotic G2 DNA damage checkpoint A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M t (more detail) 20 NA Homo sapiens

GOA IEI014615 Protein protein interactors of human gene UBOX5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBOX5 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX022818 GO:0035327 cellular component transcriptionally active chromatin The ordered and organized complex of DNA and protein that forms regions of the chromosome that are b (more detail) 20 NA Homo sapiens

GOA TAX023748 GO:0042276 biological process error prone translesion synthesis The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after repl (more detail) 20 NA Homo sapiens

GOA TAX030894 GO:0097503 biological process sialylation The covalent attachment of sialic acid to a substrate molecule. (more detail) 20 NA Homo sapiens

GOA TAX017484 GO:0009068 biological process aspartate family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate famil (more detail) 20 NA Homo sapiens

GOA MEX001882 Genes associated with Kinase Inhibitor 918505 84 7 Genes associated with Kinase Inhibitor 918505-84-7, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens

DSigDB FEX001380 Leukemia Bradbury05 23genes AssociatedProteinsPMBC Table S1 Expression of deacetylases and associated proteins in peripheral blood mononuclear cells (P (more detail) 20 16121216 Homo sapiens

GeneSigDB WIG000911 Genes involved in HS GAG degradation (more detail) 20 NA Homo sapiens

MSigDB MEX001208 Genes associated with Kinase Inhibitor gw5074 Genes associated with Kinase Inhibitor gw5074, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens

DSigDB TAX000572 Genes annotated by the GO term GO:0006029. The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. (more detail) 20 NA Homo sapiens

MSigDB WAG001545 RNA Polymerase I Promoter Escape (more detail) 20 NA Homo sapiens

Reactome MEX001726 Genes associated with Kinase Inhibitor GSK1007102B Genes associated with Kinase Inhibitor GSK1007102B, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens

DSigDB WIG000263 Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility BRCA1 and BRCA2 were identified genetically as breast cancer susceptibility genes when a single copy (more detail) 20 NA Homo sapiens

MSigDB WIG001595 Notch Signaling Notch Signaling (more detail) 20 NA Homo sapiens

Protein Lounge MEX001606 Genes associated with Kinase Inhibitor Lck Inhibitor Genes associated with Kinase Inhibitor Lck Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 20 25990557 Homo sapiens

DSigDB MEX002422 Genes associated with Kinase Inhibitor Lenvatinib Genes associated with Kinase Inhibitor Lenvatinib, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens

DSigDB WAG001438 Nicotinate and nicotinamide metabolism (more detail) 20 NA Homo sapiens

KEGG WAG000009 inhibition of cellular proliferation by gleevec The drug Gleevec (also known as imatinib mesylate or STI-571) was approved by the FDA in 2001 for th (more detail) 20 NA Homo sapiens

BioCarta WAG000705 RNA Polymerase I Transcription Termination (more detail) 20 NA Homo sapiens

Reactome WAG000455 APC Cdc20 mediated degradation of Nek2A (more detail) 20 NA Homo sapiens

Reactome TAX016422 GO:0006555 biological process methionine metabolic process The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a su (more detail) 20 NA Homo sapiens

GOA TAX000440 Genes annotated by the GO term GO:0006289. In nucleotide excision repair a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6 4 photoproducts) and chemicals (intrastrand cross links and bulky adducts). (more detail) 20 NA Homo sapiens

MSigDB WAG001522 Generic Transcription Pathway (more detail) 20 NA Homo sapiens

Reactome WAG000899 Global Genomic NER (GG NER) (more detail) 20 NA Homo sapiens

Reactome TAX001430 Genes annotated by the GO term GO:0016763. Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). (more detail) 20 NA Homo sapiens

MSigDB WIG001190 Genes involved in SHC1 events in ERBB4 signaling (more detail) 20 NA Homo sapiens

MSigDB FEX001381 Leukemia Bradbury05 23genes RelatedProteinsMC TABLE S2 Expression of deacetylases and related proteins in mononuclear cells from 23 primary AML pa (more detail) 20 16121216 Homo sapiens

GeneSigDB FEX001277 Leukemia Taghon 20genes Table 2 Expression of HOX genes in purified human precursor cell populations from various sources (more detail) 20 12764384 Homo sapiens

GeneSigDB WIG001743 Mismatch Repair Pathway in Eukaryotes Mismatch Repair Pathway in Eukaryotes (more detail) 20 NA Homo sapiens

Protein Lounge MEX001585 Genes associated with Kinase Inhibitor NCGC00346963 01 Genes associated with Kinase Inhibitor NCGC00346963-01, curated by the Drug Signature Database (DSig (more detail) 20 25990557 Homo sapiens

DSigDB MEX001484 Genes associated with Kinase Inhibitor Kinome 511 Genes associated with Kinase Inhibitor Kinome_511, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens

DSigDB WAG000115 RNA Polymerase I Promoter Clearance (more detail) 20 NA Homo sapiens

Reactome WAG000884 Dual incision reaction in GG NER (more detail) 20 NA Homo sapiens

Reactome WAG000626 igf 1 signaling pathway Insulin like growth factor 1 (IGF-1) and its receptor (IGF-1R) provide a potent proliferative siglin (more detail) 20 NA Homo sapiens

BioCarta WAG000314 RNA Polymerase I Transcription Initiation (more detail) 20 NA Homo sapiens

Reactome FOX000835 Genes in the cancer module 78 (more detail) 20 NA Homo sapiens

MSigDB WAG000615 Heparan sulfate biosynthesis Heparan sulfate (HS) and heparin (Hep) are glycosaminoglycans with repeating disaccharide units that (more detail) 20 NA Homo sapiens

KEGG TAX013507 GO:0000803 cellular component sex chromosome A chromosome involved in sex determination. (more detail) 20 NA Homo sapiens

GOA WIG000804 Genes involved in Double Strand Break Repair (more detail) 20 NA Homo sapiens

MSigDB WIG000674 Genes involved in Acyl chain remodelling of PE (more detail) 20 NA Homo sapiens

MSigDB WAG001092 Formation of incision complex in GG NER (more detail) 20 NA Homo sapiens

Reactome IEI003543 Protein protein interactors of human gene DHX36 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHX36 (SwissProt ID= (more detail) 45 17535438 Homo sapiens

I2D IEI004226 Protein protein interactors of human gene EPOR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPOR (SwissProt ID=P (more detail) 45 17535438 Homo sapiens

I2D IEI007867 Protein protein interactors of human gene MEF2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEF2A (SwissProt ID= (more detail) 45 17535438 Homo sapiens

I2D MAX002565 Cluster 6: genes down regulated in B493 6 cells (B lymphocytes) by MYC [GeneID=4609] in combination with serum but not affected by serum alone; they are also up regulated by MYC alone. Proliferation of higher eukaryotic cells is triggered by the proto-oncogene c-myc (myc), which is in (more detail) 45 NA Homo sapiens

MSigDB MOX004064 Genes associated with Computational Drug Signature ETHACRYNIC ACID Genes associated with Computational Drug Signature ETHACRYNIC ACID, curated by the Drug Signature Da (more detail) 45 25990557 Homo sapiens

DSigDB IEI011082 Protein protein interactors of human gene RBM28 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM28 (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D IEI012340 Protein protein interactors of human gene SLC25A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC25A1 (SwissProt I (more detail) 36 17535438 Homo sapiens

I2D TAX025677 GO:0046632 biological process alpha beta T cell differentiation The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell (more detail) 36 NA Homo sapiens

GOA IEI010229 Protein protein interactors of human gene POLR2L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2L (SwissProt ID (more detail) 36 17535438 Homo sapiens

I2D IEI003822 Protein protein interactors of human gene DTX3L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DTX3L (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D IEI014172 Protein protein interactors of human gene TRAIP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRAIP (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D IEI000434 Protein protein interactors of human gene AKAP8L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKAP8L (SwissProt ID (more detail) 36 17535438 Homo sapiens

I2D WIG000883 Genes involved in Glycosphingolipid metabolism (more detail) 36 NA Homo sapiens

MSigDB MOX004707 Genes associated with Computational Drug Signature dioxidanide Genes associated with Computational Drug Signature dioxidanide, curated by the Drug Signature Databa (more detail) 36 25990557 Homo sapiens

DSigDB MOX014817 Genes associated with Computational Drug Signature Rhein Genes associated with Computational Drug Signature Rhein, curated by the Drug Signature Database (DS (more detail) 36 25990557 Homo sapiens

DSigDB MOX012516 Genes associated with Computational Drug Signature emodin Genes associated with Computational Drug Signature emodin, curated by the Drug Signature Database (D (more detail) 36 25990557 Homo sapiens

DSigDB MAX001116 Genes up regulated in lymph nodes from patients with mantle cell lymphoma (MCL) compared to the non malignant hyperplastic lymph nodes. An imbalance between cellular apoptosis and survival may be critical for the pathogenesis of lymphom (more detail) 47 NA Homo sapiens

MSigDB TAX000106 Genes annotated by the GO term GO:0000075. A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. (more detail) 47 NA Homo sapiens

MSigDB MOX005053 Genes associated with Computational Drug Signature BUTHIONINE SULFOXIMINE Genes associated with Computational Drug Signature BUTHIONINE SULFOXIMINE, curated by the Drug Signa (more detail) 47 25990557 Homo sapiens

DSigDB WIG000076 Hedgehog signaling events mediated by Gli proteins (more detail) 47 NA Homo sapiens

MSigDB IEI006989 Protein protein interactors of human gene KPNA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KPNA4 (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D IEI003608 Protein protein interactors of human gene DMAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DMAP1 (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D TAX019143 GO:0016645 molecular function oxidoreductase activity, acting on the CH NH group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or el (more detail) 26 NA Homo sapiens

GOA IEI003428 Protein protein interactors of human gene DDX47 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX47 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI003435 Protein protein interactors of human gene DDX54 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX54 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI006757 Protein protein interactors of human gene KDM2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM2A (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI003056 Protein protein interactors of human gene CSN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSN2 (SwissProt ID=P (more detail) 26 17535438 Homo sapiens

I2D IEI010197 Protein protein interactors of human gene POLE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLE (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens

I2D IEI003821 Protein protein interactors of human gene DTX3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DTX3 (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens

I2D IEI008295 Protein protein interactors of human gene MSX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MSX1 (SwissProt ID=P (more detail) 26 17535438 Homo sapiens

I2D IEI000774 Protein protein interactors of human gene AQR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AQR (SwissProt ID=O6 (more detail) 26 17535438 Homo sapiens

I2D IEI004364 Protein protein interactors of human gene EXOSC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXOSC3 (SwissProt ID (more detail) 26 17535438 Homo sapiens

I2D MOX003461 Genes associated with Computational Drug Signature MLS000766263 Genes associated with Computational Drug Signature MLS000766263, curated by the Drug Signature Datab (more detail) 26 25990557 Homo sapiens

DSigDB MEX000597 Genes associated with Approved Drug mitoxantrone dihydrochloride Genes associated with Approved Drug mitoxantrone dihydrochloride, curated by the Drug Signature Data (more detail) 26 25990557 Homo sapiens

DSigDB FOX000677 Genes in the cancer module 371 (more detail) 26 NA Homo sapiens

MSigDB WIG000136 p38 MAPK signaling pathway (more detail) 26 NA Homo sapiens

MSigDB WAG000393 Glycosylphosphatidylinositol(GPI) anchor biosynthesis Cell surface proteins can be attached to the cell membrane via the glycolipid structure called glyco (more detail) 26 NA Homo sapiens

KEGG IEI006450 Protein protein interactors of human gene IPO4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IPO4 (SwissProt ID=Q (more detail) 49 17535438 Homo sapiens

I2D IEI014576 Protein protein interactors of human gene UBE2G2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2G2 (SwissProt ID (more detail) 49 17535438 Homo sapiens

I2D IEI014598 Protein protein interactors of human gene UBE2Z from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2Z (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D IEI009169 Protein protein interactors of human gene NUP205 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUP205 (SwissProt ID (more detail) 49 17535438 Homo sapiens

I2D WIG000068 FoxO family signaling (more detail) 49 NA Homo sapiens

MSigDB MAX002261 Antigen processing and presentation genes down regulated in JY cells (B lymphocytes) treated with trichostatin A (TSA) [PubChem=5562]. Histone deacetylases (HDAC) modify the architecture of chromatin, leading to decreased gene expressi (more detail) 49 NA Homo sapiens

MSigDB MOX001639 Genes associated with Computational Drug Signature Leptomycin B Genes associated with Computational Drug Signature Leptomycin B, curated by the Drug Signature Datab (more detail) 49 25990557 Homo sapiens

DSigDB IEI010225 Protein protein interactors of human gene POLR2I from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR2I (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D TAX027702 GO:0060148 biological process positive regulation of posttranscriptional gene silencing Any process that increases the frequency, rate or extent of the inactivation of gene expression by a (more detail) 23 NA Homo sapiens

GOA TAX024688 GO:0044322 cellular component endoplasmic reticulum quality control compartment A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding a (more detail) 23 NA Homo sapiens

GOA TAX000734 Genes annotated by the GO term GO:0006401. The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5' phosphodiester linkage. (more detail) 23 NA Homo sapiens

MSigDB IEI014062 Protein protein interactors of human gene TNRC6C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNRC6C (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI008296 Protein protein interactors of human gene MSX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MSX2 (SwissProt ID=P (more detail) 23 17535438 Homo sapiens

I2D TAX019203 GO:0016769 molecular function transferase activity, transferring nitrogenous groups Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor). (more detail) 23 NA Homo sapiens

GOA TAX019258 GO:0016849 molecular function phosphorus oxygen lyase activity Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation (more detail) 23 NA Homo sapiens

GOA TAX032142 GO:1901522 biological process positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellula (more detail) 23 NA Homo sapiens

GOA WIG000393 NFkB activation by Nontypeable Hemophilus influenzae The role of Hemophilus influenzae in ear infections and chronic obstructive pulmonary disease includ (more detail) 23 NA Homo sapiens

MSigDB IEI005585 Protein protein interactors of human gene GTF2H4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2H4 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D TAX026859 GO:0051187 biological process cofactor catabolic process The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is re (more detail) 51 NA Homo sapiens

GOA IEI008724 Protein protein interactors of human gene NEDD9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEDD9 (SwissProt ID= (more detail) 51 17535438 Homo sapiens

I2D MAX003381 Down regulated at 8 h following infection of primary human foreskin fibroblasts with CMV Mechanistic insights to viral replication and pathogenesis generally have come from the analysis of (more detail) 51 NA Homo sapiens

MSigDB MOX002273 Genes associated with Computational Drug Signature MK 886 Genes associated with Computational Drug Signature MK 886, curated by the Drug Signature Database (D (more detail) 51 25990557 Homo sapiens

DSigDB MOX005042 Genes associated with Computational Drug Signature oleic acid Genes associated with Computational Drug Signature oleic acid, curated by the Drug Signature Databas (more detail) 51 25990557 Homo sapiens

DSigDB IEI007825 Protein protein interactors of human gene MDN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MDN1 (SwissProt ID=Q (more detail) 31 17535438 Homo sapiens

I2D IEI009118 Protein protein interactors of human gene NTPCR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NTPCR (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI004886 Protein protein interactors of human gene FOXP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXP3 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI004081 Protein protein interactors of human gene ELF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELF1 (SwissProt ID=P (more detail) 31 17535438 Homo sapiens

I2D IEI012599 Protein protein interactors of human gene SMARCD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCD3 (SwissProt I (more detail) 31 17535438 Homo sapiens

I2D TAX023514 GO:0038128 biological process ERBB2 signaling pathway A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of rec (more detail) 31 NA Homo sapiens

GOA TAX020470 GO:0030332 molecular function cyclin binding Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies mark (more detail) 31 NA Homo sapiens

GOA WIG000023 Osteopontin mediated events (more detail) 31 NA Homo sapiens

MSigDB WIG000030 CD40/CD40L signaling (more detail) 31 NA Homo sapiens

MSigDB WIG001781 4 1BB Pathway 4-1BB Pathway (more detail) 31 NA Homo sapiens

Protein Lounge FEX000910 Colon Grade07 74genes Table 2c. Expression ratio for genes with differential expression between lymph nodepositive (UICC s (more detail) 53 17210682 Homo sapiens

GeneSigDB IEI009426 Protein protein interactors of human gene PABPN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PABPN1 (SwissProt ID (more detail) 53 17535438 Homo sapiens

I2D IEI015039 Protein protein interactors of human gene WEE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WEE1 (SwissProt ID=P (more detail) 38 17535438 Homo sapiens

I2D IEI009533 Protein protein interactors of human gene PAX6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAX6 (SwissProt ID=P (more detail) 38 17535438 Homo sapiens

I2D IEI005579 Protein protein interactors of human gene GTF2E2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2E2 (SwissProt ID (more detail) 38 17535438 Homo sapiens

I2D IEI014743 Protein protein interactors of human gene USF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USF2 (SwissProt ID=Q (more detail) 38 17535438 Homo sapiens

I2D TAX034574 GO:2000279 biological process negative regulation of DNA biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic proces (more detail) 38 NA Homo sapiens

GOA WIG001100 Genes involved in Pre NOTCH Expression and Processing (more detail) 38 NA Homo sapiens

MSigDB MOX001643 Genes associated with Computational Drug Signature TTNPB Genes associated with Computational Drug Signature TTNPB, curated by the Drug Signature Database (DS (more detail) 38 25990557 Homo sapiens

DSigDB MOX004958 Genes associated with Computational Drug Signature oxidopamine Genes associated with Computational Drug Signature oxidopamine, curated by the Drug Signature Databa (more detail) 38 25990557 Homo sapiens

DSigDB MOX004466 Genes associated with Computational Drug Signature OZONE Genes associated with Computational Drug Signature OZONE, curated by the Drug Signature Database (DS (more detail) 38 25990557 Homo sapiens

DSigDB WIG000064 FAS (CD95) signaling pathway (more detail) 38 NA Homo sapiens

MSigDB IEI005461 Protein protein interactors of human gene GPS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GPS2 (SwissProt ID=Q (more detail) 40 17535438 Homo sapiens

I2D IEI009419 Protein protein interactors of human gene PAAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAAF1 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D IEI006454 Protein protein interactors of human gene IPO9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IPO9 (SwissProt ID=Q (more detail) 40 17535438 Homo sapiens

I2D IEI005853 Protein protein interactors of human gene HIPK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HIPK3 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D TAX019274 GO:0016877 molecular function ligase activity, forming carbon sulfur bonds Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis (more detail) 40 NA Homo sapiens

GOA IEI011006 Protein protein interactors of human gene RARG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RARG (SwissProt ID=P (more detail) 40 17535438 Homo sapiens

I2D TAX030505 GO:0090342 biological process regulation of cell aging Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progressi (more detail) 40 NA Homo sapiens

GOA TAX030484 GO:0090311 biological process regulation of protein deacetylation Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of a (more detail) 40 NA Homo sapiens

GOA MOX004346 Genes associated with Computational Drug Signature methyldopa Genes associated with Computational Drug Signature methyldopa, curated by the Drug Signature Databas (more detail) 40 25990557 Homo sapiens

DSigDB IEI006343 Protein protein interactors of human gene IL2RB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL2RB (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D TAX026210 GO:0048536 biological process spleen development The process whose specific outcome is the progression of the spleen over time, from its formation to (more detail) 33 NA Homo sapiens

GOA IEI006975 Protein protein interactors of human gene KMT2D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KMT2D (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D TAX025335 GO:0045911 biological process positive regulation of DNA recombination Any process that activates or increases the frequency, rate or extent of DNA recombination. (more detail) 33 NA Homo sapiens

GOA IEI002200 Protein protein interactors of human gene CDC7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC7 (SwissProt ID=O (more detail) 33 17535438 Homo sapiens

I2D IEI014845 Protein protein interactors of human gene VASN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VASN (SwissProt ID=Q (more detail) 33 17535438 Homo sapiens

I2D WIG000261 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling Ang II binding to AT1-R triggers the activation of Ca2+ signaling and PKC. The signal is then transm (more detail) 33 NA Homo sapiens

MSigDB WAG001437 Histidine metabolism (more detail) 33 NA Homo sapiens

KEGG IEI009022 Protein protein interactors of human gene NR1H3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR1H3 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D IEI007646 Protein protein interactors of human gene MAP2K2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP2K2 (SwissProt ID (more detail) 42 17535438 Homo sapiens

I2D TAX016792 GO:0007140 biological process male meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male g (more detail) 42 NA Homo sapiens

GOA IEI002712 Protein protein interactors of human gene CNDP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNDP2 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D WAG001053 Presenilin action in Notch and Wnt signaling (more detail) 42 NA Homo sapiens

NCI-Nature Curated TAX028943 GO:0070461 cellular component SAGA type complex A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the e (more detail) 28 NA Homo sapiens

GOA IEI003045 Protein protein interactors of human gene CSF3R from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSF3R (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D TAX027361 GO:0052312 biological process modulation of transcription in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of transcription in a secon (more detail) 28 NA Homo sapiens

GOA IEI015103 Protein protein interactors of human gene XBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XBP1 (SwissProt ID=P (more detail) 28 17535438 Homo sapiens

I2D IEI008824 Protein protein interactors of human gene NHP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NHP2 (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI009604 Protein protein interactors of human gene PCGF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCGF3 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D WIG000317 Erk1/Erk2 Mapk Signaling pathway The p44/42 MAP Kinase pathway consists of a protein kinase cascade linking growth and differentiatio (more detail) 28 NA Homo sapiens

MSigDB TAX000622 Genes annotated by the GO term GO:0040029. Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. (more detail) 28 NA Homo sapiens

MSigDB WIG000333 Growth Hormone Signaling Pathway Growth hormone plays a major role in regulating growth during childhood and adolescence and also reg (more detail) 28 NA Homo sapiens

MSigDB MOX004282 Genes associated with Computational Drug Signature MANEB Genes associated with Computational Drug Signature MANEB, curated by the Drug Signature Database (DS (more detail) 28 25990557 Homo sapiens

DSigDB PEX000233 PHD: PHD finger PHD folds into an interleaved type of Zn-finger chelating 2 Zn ions in a similar manner to that of t (more detail) 28 NA Homo sapiens

Pfam WIG000240 T Cell Signal Transduction na (more detail) 44 NA Homo sapiens

MSigDB WIG000148 Presenilin action in Notch and Wnt signaling (more detail) 44 NA Homo sapiens

MSigDB WIG000917 Genes involved in Interleukin 3, 5 and GM CSF signaling (more detail) 44 NA Homo sapiens

MSigDB MAX002668 Top 50 up regulated markers distinguishing diffuse large B cell lymphoma (DLBCL) from follicular lymphoma (FL) samples. Diffuse large B-cell lymphoma (DLBCL), the most common lymphoid malignancy in adults, is curable in (more detail) 44 NA Homo sapiens

MSigDB MEX000877 Genes associated with Approved Drug idarubicin hydrochloride Genes associated with Approved Drug idarubicin hydrochloride, curated by the Drug Signature Database (more detail) 44 25990557 Homo sapiens

DSigDB IEI002729 Protein protein interactors of human gene CNOT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNOT1 (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D IEI009687 Protein protein interactors of human gene PDHA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDHA1 (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D TAX019297 GO:0016903 molecular function oxidoreductase activity, acting on the aldehyde or oxo group of donors Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts (more detail) 44 NA Homo sapiens

GOA IEI000388 Protein protein interactors of human gene AHNAK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AHNAK (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D TAX027011 GO:0051445 biological process regulation of meiotic cell cycle Any process that modulates the rate or extent of progression through the meiotic cell cycle. (more detail) 44 NA Homo sapiens

GOA IEI004808 Protein protein interactors of human gene FLII from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FLII (SwissProt ID=Q (more detail) 44 17535438 Homo sapiens

I2D WEX000002 AMPK Signaling The genes related to ampk signaling (signaling pathways) in tumor using next-generation sequencer (N (more detail) 44 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas MOX007041 Genes associated with Computational Drug Signature apigenin Genes associated with Computational Drug Signature apigenin, curated by the Drug Signature Database (more detail) 46 25990557 Homo sapiens

DSigDB TAX000238 Genes annotated by the GO term GO:0006650. The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O acyl, O alkyl, or O alkenyl group attached to the glycerol residue. (more detail) 46 NA Homo sapiens

MSigDB MOX002989 Genes associated with Computational Drug Signature 1 AMINO 4 HYDROXYANTHRAQUINONE Genes associated with Computational Drug Signature 1-AMINO-4-HYDROXYANTHRAQUINONE, curated by the Dr (more detail) 46 25990557 Homo sapiens

DSigDB IEI013672 Protein protein interactors of human gene THOC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THOC1 (SwissProt ID= (more detail) 46 17535438 Homo sapiens

I2D IEI010312 Protein protein interactors of human gene PPID from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPID (SwissProt ID=Q (more detail) 46 17535438 Homo sapiens

I2D IEI007474 Protein protein interactors of human gene LSM4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSM4 (SwissProt ID=Q (more detail) 46 17535438 Homo sapiens

I2D TAX025058 GO:0045309 molecular function protein phosphorylated amino acid binding Interacting selectively and non-covalently with a phosphorylated amino acid residue within a protein (more detail) 46 NA Homo sapiens

GOA TAX021840 GO:0032885 biological process regulation of polysaccharide biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 35 NA Homo sapiens

GOA TAX022745 GO:0035137 biological process hindlimb morphogenesis The process in which the anatomical structures of the hindlimb are generated and organized. (more detail) 35 NA Homo sapiens

GOA IEI008790 Protein protein interactors of human gene NFIA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFIA (SwissProt ID=Q (more detail) 35 17535438 Homo sapiens

I2D TAX027300 GO:0051973 biological process positive regulation of telomerase activity Any process that activates or increases the frequency, rate or extent of telomerase activity, the ca (more detail) 35 NA Homo sapiens

GOA IEI010375 Protein protein interactors of human gene PPP1R8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R8 (SwissProt ID (more detail) 35 17535438 Homo sapiens

I2D IEI013128 Protein protein interactors of human gene STK38 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STK38 (SwissProt ID= (more detail) 35 17535438 Homo sapiens

I2D WIG001761 ATM Pathway ATM Pathway (more detail) 35 NA Homo sapiens

Protein Lounge WAG000989 Bladder cancer The urothelium covers the lumil surface of almost the entire uriry tract, extending from the rel pel (more detail) 35 NA Homo sapiens

KEGG WAG001476 Hedgehog signaling events mediated by Gli proteins (more detail) 35 NA Homo sapiens

NCI-Nature Curated FOX000221 Neighborhood of TDG Neighborhood of TDG thymine-DNA glycosylase in the GNF2 expression compendium (more detail) 35 NA Homo sapiens

MSigDB TAX016185 GO:0006206 biological process pyrimidine nucleobase metabolic process The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogeno (more detail) 19 NA Homo sapiens

GOA WIG000753 Genes involved in Chondroitin sulfate biosynthesis (more detail) 19 NA Homo sapiens

MSigDB TAX015295 GO:0004653 molecular function polypeptide N acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosami (more detail) 19 NA Homo sapiens

GOA WAG001130 RNA Polymerase I Chain Elongation (more detail) 19 NA Homo sapiens

Reactome TAX016253 GO:0006312 biological process mitotic recombination The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homolo (more detail) 19 NA Homo sapiens

GOA TAX001365 Genes annotated by the GO term GO:0031202. An activity which binds RNA and functions to assist splicing of substrate RNA(s) by facilitating the formation and stabilization of a catalytic conformation in which the splice junctions of the RNA(s) to be spliced are positioned for a transesterification reaction that occurs between two sites within the RNA(s) to be spliced. (more detail) 19 NA Homo sapiens

MSigDB MEX001650 Genes associated with Kinase Inhibitor GNE 7915 Genes associated with Kinase Inhibitor GNE-7915, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB WAG000724 RNA Polymerase I Transcription (more detail) 19 NA Homo sapiens

Reactome MAX000513 Substrates of PRKDC [GeneID=5591]. Double-strand breaks (DSBs) arise endogenously during normal cellular processes and exogenously by g (more detail) 19 NA Homo sapiens

MSigDB WAG001346 Regulation of APC/C activators between G1/S and early anaphase (more detail) 19 NA Homo sapiens

Reactome WIG000960 Genes involved in Lagging Strand Synthesis (more detail) 19 NA Homo sapiens

MSigDB WIG001169 Genes involved in RNA Polymerase III Transcription Termination (more detail) 19 NA Homo sapiens

MSigDB TAX015206 GO:0004529 molecular function exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molec (more detail) 19 NA Homo sapiens

GOA MOX015246 Genes associated with Computational Drug Signature Sunitinib Genes associated with Computational Drug Signature Sunitinib, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB WIG000262 ATM Signaling Pathway The ataxia telangiectasia-mutated gene (ATM) encodes a protein kinase that acts as a tumor suppresso (more detail) 19 NA Homo sapiens

MSigDB WIG001992 Urea cycle and metabolism of amino groups Urea cycle and metabolism of amino groups (more detail) 19 NA Homo sapiens

WikiPathway MEX002011 Genes associated with Kinase Inhibitor SB 203580 Genes associated with Kinase Inhibitor SB 203580, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB TAX013474 GO:0000737 biological process DNA catabolic process, endonucleolytic The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of i (more detail) 19 NA Homo sapiens

GOA MEX001303 Genes associated with Kinase Inhibitor Kinome 1198 Genes associated with Kinase Inhibitor Kinome_1198, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB MEX001890 Genes associated with Kinase Inhibitor Kinome 1221 Genes associated with Kinase Inhibitor Kinome_1221, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB MEX002301 Genes associated with Kinase Inhibitor TCMDC 138201 Genes associated with Kinase Inhibitor TCMDC-138201, curated by the Drug Signature Database (DSigDB) (more detail) 19 25990557 Homo sapiens

DSigDB WAG000466 APC/C:Cdc20 mediated degradation of mitotic proteins (more detail) 19 NA Homo sapiens

Reactome WIG000293 Complement Pathway The complement pathway consists of a series of over thirty proteins in plasma that are part of the i (more detail) 19 NA Homo sapiens

MSigDB TAX001440 Genes annotated by the GO term GO:0019198. The catalysis of phosphate removal from a phosphotyrosine using aspartic acid as a nucleophile in a metal dependent manner. (more detail) 19 NA Homo sapiens

MSigDB WIG000651 Genes involved in Abortive elongation of HIV 1 transcript in the absence of Tat (more detail) 19 NA Homo sapiens

MSigDB MEX001386 Genes associated with Kinase Inhibitor Masitinib Genes associated with Kinase Inhibitor Masitinib, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB MEX002268 Genes associated with Kinase Inhibitor indirubin deriv. 7a Genes associated with Kinase Inhibitor indirubin deriv. 7a, curated by the Drug Signature Database ( (more detail) 19 25990557 Homo sapiens

DSigDB MEX001463 Genes associated with Kinase Inhibitor LDN193189 Genes associated with Kinase Inhibitor LDN193189, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB TAX017617 GO:0009226 biological process nucleotide sugar biosynthetic process The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide- (more detail) 19 NA Homo sapiens

GOA IEI010173 Protein protein interactors of human gene PNRC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PNRC1 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX017641 GO:0009264 biological process deoxyribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound (more detail) 19 NA Homo sapiens

GOA TAX014915 GO:0004016 molecular function adenylate cyclase activity Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. (more detail) 19 NA Homo sapiens

GOA TAX017623 GO:0009235 biological process cobalamin metabolic process The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin chara (more detail) 19 NA Homo sapiens

GOA TAX022827 GO:0035338 biological process long chain fatty acyl CoA biosynthetic process The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any de (more detail) 19 NA Homo sapiens

GOA TAX023426 GO:0036508 biological process protein alpha 1,2 demannosylation The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein. (more detail) 19 NA Homo sapiens

GOA TAX029515 GO:0071514 biological process genetic imprinting Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 19 NA Homo sapiens

GOA IEI013619 Protein protein interactors of human gene TFPI from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TFPI (SwissProt ID=P (more detail) 19 17535438 Homo sapiens

I2D IEI011206 Protein protein interactors of human gene RFFL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RFFL (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D IEI010290 Protein protein interactors of human gene PPAN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPAN (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D TAX029233 GO:0070987 biological process error free translesion synthesis The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after repl (more detail) 19 NA Homo sapiens

GOA TAX022408 GO:0034311 biological process diol metabolic process The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, g (more detail) 19 NA Homo sapiens

GOA TAX015963 GO:0005839 cellular component proteasome core complex A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex. (more detail) 19 NA Homo sapiens

GOA TAX024556 GO:0043984 biological process histone H4 K16 acetylation The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 (more detail) 19 NA Homo sapiens

GOA TAX017546 GO:0009148 biological process pyrimidine nucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate (more detail) 19 NA Homo sapiens

GOA TAX023425 GO:0036507 biological process protein demannosylation The removal of one or more mannose residues from a mannosylated protein. (more detail) 19 NA Homo sapiens

GOA TAX018854 GO:0016075 biological process rRNA catabolic process The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural (more detail) 19 NA Homo sapiens

GOA TAX024211 GO:0043189 cellular component H4/H2A histone acetyltransferase complex A multisubunit complex that catalyzes the acetylation of histones H4 and H2A. (more detail) 19 NA Homo sapiens

GOA TAX017496 GO:0009084 biological process glutamine family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the glutamine famil (more detail) 19 NA Homo sapiens

GOA TAX024020 GO:0042789 biological process mRNA transcription by RNA polymerase II The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating (more detail) 19 NA Homo sapiens

GOA TAX022793 GO:0035267 cellular component NuA4 histone acetyltransferase complex A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and struct (more detail) 19 NA Homo sapiens

GOA TAX019291 GO:0016895 molecular function exodeoxyribonuclease activity, producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide r (more detail) 19 NA Homo sapiens

GOA IEI014301 Protein protein interactors of human gene TRMT1L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRMT1L (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D TAX027067 GO:0051570 biological process regulation of histone H3 K9 methylation Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group (more detail) 19 NA Homo sapiens

GOA TAX019536 GO:0018410 biological process C terminal protein amino acid modification The alteration of the C-terminal amino acid residue in a protein. (more detail) 19 NA Homo sapiens

GOA IEI006051 Protein protein interactors of human gene HSF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSF2 (SwissProt ID=Q (more detail) 48 17535438 Homo sapiens

I2D IEI005672 Protein protein interactors of human gene H2BC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2BC4 (SwissProt ID= (more detail) 48 17535438 Homo sapiens

I2D IEI005596 Protein protein interactors of human gene GTF3C5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF3C5 (SwissProt ID (more detail) 48 17535438 Homo sapiens

I2D MOX017178 Genes associated with Computational Drug Signature nocodazole Genes associated with Computational Drug Signature nocodazole, curated by the Drug Signature Databas (more detail) 48 25990557 Homo sapiens

DSigDB MOX004940 Genes associated with Computational Drug Signature carboplatin Genes associated with Computational Drug Signature carboplatin, curated by the Drug Signature Databa (more detail) 48 25990557 Homo sapiens

DSigDB MOX015670 Genes associated with Computational Drug Signature Tyrphostin AG 538 Genes associated with Computational Drug Signature Tyrphostin AG 538, curated by the Drug Signature (more detail) 48 25990557 Homo sapiens

DSigDB IEI010600 Protein protein interactors of human gene PSAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSAP (SwissProt ID=P (more detail) 50 17535438 Homo sapiens

I2D FOX000129 Neighborhood of DENR Neighborhood of DENR density-regulated protein in the GNF2 expression compendium (more detail) 50 NA Homo sapiens

MSigDB IEI006194 Protein protein interactors of human gene IFNB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFNB1 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI014090 Protein protein interactors of human gene TOP3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TOP3A (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI010174 Protein protein interactors of human gene PNRC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PNRC2 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D TAX027066 GO:0051569 biological process regulation of histone H3 K4 methylation Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group (more detail) 25 NA Homo sapiens

GOA IEI008401 Protein protein interactors of human gene MXD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MXD1 (SwissProt ID=Q (more detail) 25 17535438 Homo sapiens

I2D IEI004818 Protein protein interactors of human gene FLT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FLT3 (SwissProt ID=P (more detail) 25 17535438 Homo sapiens

I2D IEI011610 Protein protein interactors of human gene RPS6KB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS6KB2 (SwissProt I (more detail) 25 17535438 Homo sapiens

I2D TAX019269 GO:0016866 molecular function intramolecular transferase activity Catalysis of the transfer of a functional group from one position to another within a single molecul (more detail) 25 NA Homo sapiens

GOA IEI011216 Protein protein interactors of human gene RFWD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RFWD3 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI015291 Protein protein interactors of human gene ZEB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZEB1 (SwissProt ID=P (more detail) 25 17535438 Homo sapiens

I2D WIG000121 C MYC pathway (more detail) 25 NA Homo sapiens

MSigDB MOX003748 Genes associated with Computational Drug Signature bleomycin Genes associated with Computational Drug Signature bleomycin, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB WIG001391 Vemurafenib Pathway, Pharmacodynamics Vemurafenib Pathway, Pharmacodynamics (more detail) 25 NA Homo sapiens

PharmGKB WIG000535 Glycosylphosphatidylinositol(GPI) anchor biosynthesis Cell surface proteins can be attached to the cell membrane via the glycolipid structure called glyco (more detail) 25 NA Homo sapiens

MSigDB MOX000251 Genes associated with Computational Drug Signature Hydroxytyrosol Genes associated with Computational Drug Signature Hydroxytyrosol, curated by the Drug Signature Dat (more detail) 25 25990557 Homo sapiens

DSigDB MOX014571 Genes associated with Computational Drug Signature podophyllotoxin Genes associated with Computational Drug Signature podophyllotoxin, curated by the Drug Signature Da (more detail) 25 25990557 Homo sapiens

DSigDB TAX001270 Genes annotated by the GO term GO:0019205. Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate. (more detail) 25 NA Homo sapiens

MSigDB TAX001225 Genes annotated by the GO term GO:0004879. A ligand dependent receptor found in the nucleus of the cell. (more detail) 25 NA Homo sapiens

MSigDB WIG001454 CNTF Signaling CNTF Signaling (more detail) 37 NA Homo sapiens

Protein Lounge WIG000668 Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events (more detail) 37 NA Homo sapiens

MSigDB MOX003827 Genes associated with Computational Drug Signature chlorambucil Genes associated with Computational Drug Signature chlorambucil, curated by the Drug Signature Datab (more detail) 37 25990557 Homo sapiens

DSigDB FEX000412 Breast Adler06 39genes SuppTable 3. MYC target genes that are co-activated by CSN5 expression. (more detail) 37 16518402 Homo sapiens

GeneSigDB MEX000388 Genes associated with Approved Drug progesterone Genes associated with Approved Drug progesterone, curated by the Drug Signature Database (DSigDB). (more detail) 37 25990557 Homo sapiens

DSigDB MOX016009 Genes associated with Computational Drug Signature edaravone Genes associated with Computational Drug Signature edaravone, curated by the Drug Signature Database (more detail) 37 25990557 Homo sapiens

DSigDB MOX005301 Genes associated with Computational Drug Signature 1,10 Phenanthroline 5,6 dione Genes associated with Computational Drug Signature 1,10-Phenanthroline-5,6-dione, curated by the Dru (more detail) 37 25990557 Homo sapiens

DSigDB IEI009035 Protein protein interactors of human gene NR3C2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR3C2 (SwissProt ID= (more detail) 37 17535438 Homo sapiens

I2D TAX025249 GO:0045740 biological process positive regulation of DNA replication Any process that activates or increases the frequency, rate or extent of DNA replication. (more detail) 37 NA Homo sapiens

GOA TAX016870 GO:0007257 biological process activation of JUN kinase activity The initiation of the activity of the inactive enzyme JUN kinase (JNK). (more detail) 37 NA Homo sapiens

GOA IEI002467 Protein protein interactors of human gene CHD7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD7 (SwissProt ID=Q (more detail) 30 17535438 Homo sapiens

I2D TAX022762 GO:0035198 molecular function miRNA binding Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed (more detail) 30 NA Homo sapiens

GOA IEI010805 Protein protein interactors of human gene PYCR3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PYCR3 (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D TAX021980 GO:0033120 biological process positive regulation of RNA splicing Any process that activates or increases the frequency, rate or extent of RNA splicing. (more detail) 30 NA Homo sapiens

GOA TAX022779 GO:0035250 molecular function UDP galactosyltransferase activity Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule. (more detail) 30 NA Homo sapiens

GOA IEI007650 Protein protein interactors of human gene MAP2K6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP2K6 (SwissProt ID (more detail) 30 17535438 Homo sapiens

I2D IEI003339 Protein protein interactors of human gene DCAF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCAF6 (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D TAX025706 GO:0046685 biological process response to arsenic containing substance Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 30 NA Homo sapiens

GOA IEI007719 Protein protein interactors of human gene MARCKS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MARCKS (SwissProt ID (more detail) 30 17535438 Homo sapiens

I2D IEI009023 Protein protein interactors of human gene NR1H4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR1H4 (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D IEI008842 Protein protein interactors of human gene NIPBL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NIPBL (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D WIG001701 TNFR2 Pathway TNFR2 Pathway (more detail) 30 NA Homo sapiens

Protein Lounge MOX004898 Genes associated with Computational Drug Signature IDARUBICIN Genes associated with Computational Drug Signature IDARUBICIN, curated by the Drug Signature Databas (more detail) 30 25990557 Homo sapiens

DSigDB WAG000257 IFN gamma pathway (more detail) 30 NA Homo sapiens

NCI-Nature Curated MOX003746 Genes associated with Computational Drug Signature dicumarol Genes associated with Computational Drug Signature dicumarol, curated by the Drug Signature Database (more detail) 30 25990557 Homo sapiens

DSigDB TAX016274 GO:0006356 biological process regulation of transcription by RNA polymerase I Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase (more detail) 30 NA Homo sapiens

GOA MAX002137 Overconnected mutated transcription factors regulating genes within the breast cancer amplicome. A single cancer cell contains large numbers of genetic alterations that in combination create the ma (more detail) 22 NA Homo sapiens

MSigDB TAX028979 GO:0070530 molecular function K63 linked polyubiquitin modification dependent protein binding Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkage (more detail) 22 NA Homo sapiens

GOA TAX001411 Genes annotated by the GO term GO:0008757. Catalysis of the transfer of a methyl group from S adenosyl L methionine to a substrate. (more detail) 22 NA Homo sapiens

MSigDB TAX033552 GO:1904666 biological process regulation of ubiquitin protein ligase activity Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity. (more detail) 22 NA Homo sapiens

GOA IEI003093 Protein protein interactors of human gene CSTF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSTF3 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D TAX015870 GO:0005682 cellular component U5 snRNP A ribonucleoprotein complex that contains small nuclear RNA U5. (more detail) 22 NA Homo sapiens

GOA TAX034829 GO:2000637 biological process positive regulation of gene silencing by miRNA Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA. (more detail) 22 NA Homo sapiens

GOA IEI005062 Protein protein interactors of human gene GAR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GAR1 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D WAG000857 Retinoic acid receptors mediated signaling (more detail) 22 NA Homo sapiens

NCI-Nature Curated WIG000361 Insulin Signaling Pathway The appropriate signaling through the insulin pathway is critical for the regulation of glucose leve (more detail) 22 NA Homo sapiens

MSigDB MOX001078 Genes associated with Computational Drug Signature 3 aminobenzamide Genes associated with Computational Drug Signature 3-aminobenzamide, curated by the Drug Signature D (more detail) 22 25990557 Homo sapiens

DSigDB MOX002028 Genes associated with Computational Drug Signature gambogic acid Genes associated with Computational Drug Signature gambogic acid, curated by the Drug Signature Data (more detail) 22 25990557 Homo sapiens

DSigDB MOX001510 Genes associated with Computational Drug Signature 24939 16 0 Genes associated with Computational Drug Signature 24939-16-0, curated by the Drug Signature Databas (more detail) 22 25990557 Homo sapiens

DSigDB WAG000636 tumor suppressor arf inhibits ribosomal biogenesis Cyclin-dependent kise inhibitor-2A (CDKN2A) goes by the colloquial desigtion p16, which is sometimes (more detail) 22 NA Homo sapiens

BioCarta WAG000814 Methionine metabolism (more detail) 22 NA Homo sapiens

KEGG IEI007660 Protein protein interactors of human gene MAP3K2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP3K2 (SwissProt ID (more detail) 39 17535438 Homo sapiens

I2D IEI005637 Protein protein interactors of human gene H1 0 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H1-0 (SwissProt ID=P (more detail) 39 17535438 Homo sapiens

I2D TAX000684 Genes annotated by the GO term GO:0051090. Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. (more detail) 39 NA Homo sapiens

MSigDB WIG000067 FOXM1 transcription factor network (more detail) 39 NA Homo sapiens

MSigDB MOX006076 Genes associated with Computational Drug Signature 4 Hydroxytamoxifen Genes associated with Computational Drug Signature 4-Hydroxytamoxifen, curated by the Drug Signature (more detail) 39 25990557 Homo sapiens

DSigDB TAX001026 Genes annotated by the GO term GO:0005840. An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. (more detail) 39 NA Homo sapiens

MSigDB IEI015245 Protein protein interactors of human gene ZC3H18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZC3H18 (SwissProt ID (more detail) 41 17535438 Homo sapiens

I2D IEI004059 Protein protein interactors of human gene EIF4EBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF4EBP1 (SwissProt (more detail) 41 17535438 Homo sapiens

I2D IEI007644 Protein protein interactors of human gene MAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP2 (SwissProt ID=P (more detail) 41 17535438 Homo sapiens

I2D IEI014779 Protein protein interactors of human gene USP34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP34 (SwissProt ID= (more detail) 41 17535438 Homo sapiens

I2D IEI011521 Protein protein interactors of human gene RPL26L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL26L1 (SwissProt I (more detail) 41 17535438 Homo sapiens

I2D IEI011633 Protein protein interactors of human gene RRM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRM1 (SwissProt ID=P (more detail) 41 17535438 Homo sapiens

I2D MOX000342 Genes associated with Computational Drug Signature FLUORANTHENE Genes associated with Computational Drug Signature FLUORANTHENE, curated by the Drug Signature Datab (more detail) 41 25990557 Homo sapiens

DSigDB TAX021996 GO:0033144 biological process negative regulation of intracellular steroid hormone receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any in (more detail) 32 NA Homo sapiens

GOA IEI001014 Protein protein interactors of human gene ATF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATF1 (SwissProt ID=P (more detail) 32 17535438 Homo sapiens

I2D IEI003833 Protein protein interactors of human gene DUSP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP1 (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D IEI008032 Protein protein interactors of human gene MLLT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MLLT1 (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D IEI002542 Protein protein interactors of human gene CHTOP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHTOP (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D IEI009754 Protein protein interactors of human gene PES1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PES1 (SwissProt ID=O (more detail) 32 17535438 Homo sapiens

I2D WIG001694 Thrombopoietin Pathway Thrombopoietin Pathway (more detail) 32 NA Homo sapiens

Protein Lounge MOX016967 Genes associated with Computational Drug Signature Fulvestrant Genes associated with Computational Drug Signature Fulvestrant, curated by the Drug Signature Databa (more detail) 32 25990557 Homo sapiens

DSigDB TAX013979 GO:0001974 biological process blood vessel remodeling The reorganization or renovation of existing blood vessels. (more detail) 32 NA Homo sapiens

GOA TAX022802 GO:0035282 biological process segmentation The regionalization process that divides an organism or part of an organism into a series of semi-re (more detail) 43 NA Homo sapiens

GOA IEI007271 Protein protein interactors of human gene LIMA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LIMA1 (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D IEI011768 Protein protein interactors of human gene SAFB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SAFB2 (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D IEI002585 Protein protein interactors of human gene CKS1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CKS1B (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D WIG000082 FOXA1 transcription factor network (more detail) 43 NA Homo sapiens

MSigDB WAG000259 Angiopoietin receptor Tie2 mediated signaling (more detail) 43 NA Homo sapiens

NCI-Nature Curated WIG001582 Neuropathic Pain Signaling in Dorsal Horn Neurons Neuropathic Pain - Signaling in Dorsal Horn Neurons (more detail) 43 NA Homo sapiens

Protein Lounge WAG000441 Signaling events mediated by PTP1B (more detail) 43 NA Homo sapiens

NCI-Nature Curated TAX027383 GO:0052472 biological process modulation by host of symbiont transcription Any process in which an organism modulates the frequency, rate or extent of its symbiont's transcrip (more detail) 27 NA Homo sapiens

GOA IEI013580 Protein protein interactors of human gene TEX10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TEX10 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D TAX020143 GO:0021983 biological process pituitary gland development The progression of the pituitary gland over time from its initial formation until its mature state. (more detail) 27 NA Homo sapiens

GOA TAX024532 GO:0043921 biological process modulation by host of viral transcription Any process in which a host organism modulates the frequency, rate or extent of viral transcription. (more detail) 27 NA Homo sapiens

GOA TAX000234 Genes annotated by the GO term GO:0006006. The chemical reactions and pathways involving glucose, the aldohexose gluco hexose. D glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo and hetero oligosaccharides and polysaccharides. (more detail) 27 NA Homo sapiens

MSigDB WIG000773 Genes involved in CREB phosphorylation through the activation of Ras (more detail) 27 NA Homo sapiens

MSigDB MOX001652 Genes associated with Computational Drug Signature Artenimol Genes associated with Computational Drug Signature Artenimol, curated by the Drug Signature Database (more detail) 27 25990557 Homo sapiens

DSigDB WIG000210 Genes related to IL4 rceptor signaling in B lymphocytes na (more detail) 27 NA Homo sapiens

MSigDB WIG001226 Genes involved in Signalling to RAS (more detail) 27 NA Homo sapiens

MSigDB WIG000294 Transcription factor CREB and its extracellular signals The transcription factor CREB binds the cyclic AMP response element (CRE) and activates transcriptio (more detail) 27 NA Homo sapiens

MSigDB MOX013784 Genes associated with Computational Drug Signature morin Genes associated with Computational Drug Signature morin, curated by the Drug Signature Database (DS (more detail) 27 25990557 Homo sapiens

DSigDB WAG001003 Phenylalanine, tyrosine and tryptophan biosynthesis (more detail) 27 NA Homo sapiens

KEGG FEX000180 Brain Saigusa05 40genes Table 2. Most frequently gained and/or lost clones (more detail) 27 16232199 Homo sapiens

GeneSigDB FOX000174 Neighborhood of MSH2 Neighborhood of MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) in the GNF2 expres (more detail) 27 NA Homo sapiens

MSigDB TAX025676 GO:0046631 biological process alpha beta T cell activation The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, (more detail) 45 NA Homo sapiens

GOA TAX027563 GO:0055081 biological process anion homeostasis Any process involved in the maintenance of an internal steady state of anions within an organism or (more detail) 45 NA Homo sapiens

GOA WEX000039 Hedgehog Signaling The genes related to hedgehog signaling (signaling pathways) in tumor using next-generation sequence (more detail) 45 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI010104 Protein protein interactors of human gene PLOD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLOD2 (SwissProt ID= (more detail) 45 17535438 Homo sapiens

I2D MOX016935 Genes associated with Computational Drug Signature okadaic acid Genes associated with Computational Drug Signature okadaic acid, curated by the Drug Signature Datab (more detail) 45 25990557 Homo sapiens

DSigDB MOX016525 Genes associated with Computational Drug Signature niclosamide Genes associated with Computational Drug Signature niclosamide, curated by the Drug Signature Databa (more detail) 45 25990557 Homo sapiens

DSigDB WIG000083 FOXA2 and FOXA3 transcription factor networks (more detail) 45 NA Homo sapiens

MSigDB FEX000109 BoneMarrow Jeong04 50genes Table 2. First 50 most enriched genes in UCB-derived MSCs (more detail) 45 15790779 Homo sapiens

GeneSigDB MOX003495 Genes associated with Computational Drug Signature Crizotinib Genes associated with Computational Drug Signature Crizotinib, curated by the Drug Signature Databas (more detail) 47 25990557 Homo sapiens

DSigDB WAG001303 Formation of the ternary complex, and subsequently, the 43S complex (more detail) 47 NA Homo sapiens

Reactome MOX000424 Genes associated with Computational Drug Signature Zebularine Genes associated with Computational Drug Signature Zebularine, curated by the Drug Signature Databas (more detail) 47 25990557 Homo sapiens

DSigDB TAX027186 GO:0051784 biological process negative regulation of nuclear division Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the (more detail) 47 NA Homo sapiens

GOA IEI008245 Protein protein interactors of human gene MRPS27 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPS27 (SwissProt ID (more detail) 47 17535438 Homo sapiens

I2D IEI009603 Protein protein interactors of human gene PCGF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCGF2 (SwissProt ID= (more detail) 47 17535438 Homo sapiens

I2D IEI006973 Protein protein interactors of human gene KMT2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KMT2B (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D IEI008562 Protein protein interactors of human gene NANS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NANS (SwissProt ID=Q (more detail) 49 17535438 Homo sapiens

I2D IEI007741 Protein protein interactors of human gene MAT2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAT2A (SwissProt ID= (more detail) 49 17535438 Homo sapiens

I2D IEI007437 Protein protein interactors of human gene LRRC59 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRRC59 (SwissProt ID (more detail) 49 17535438 Homo sapiens

I2D FEX001516 Leukemia Achiron07 55genes Table 2 Apoptosis-related genes operating in acute MS relapse (more detail) 49 17804543 Homo sapiens

GeneSigDB MAX001394 Genes up regulated in AIDS related primary effusion lymphoma (PEL) samples compared to other tumor subtypes and normal B lymphocytes. AIDS-related primary effusion lymphoma (PEL) is an HIV-associated malignancy characterized by the ab (more detail) 49 NA Homo sapiens

MSigDB FEX002185 Lymphoma Kari03 62genes Table S3c.Signature Membership Unique Genes: FDFT1 farnesyl-diphosphate farnesyltransferase 1 Signat (more detail) 49 12782714 Homo sapiens

GeneSigDB TAX001427 Genes annotated by the GO term GO:0016747. Catalysis of the transfer of an acyl group, other than amino acyl, from one compound (donor) to another (acceptor). (more detail) 49 NA Homo sapiens

MSigDB MOX005018 Genes associated with Computational Drug Signature 506 26 3 Genes associated with Computational Drug Signature 506-26-3, curated by the Drug Signature Database (more detail) 49 25990557 Homo sapiens

DSigDB IEI013677 Protein protein interactors of human gene THOC7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THOC7 (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D IEI005271 Protein protein interactors of human gene GLUD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLUD1 (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D TAX034917 GO:2000772 biological process regulation of cellular senescence Any process that modulates the frequency, rate or extent of cellular senescence. (more detail) 34 NA Homo sapiens

GOA IEI010671 Protein protein interactors of human gene PSPC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSPC1 (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D IEI008205 Protein protein interactors of human gene MRPL37 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPL37 (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D IEI011292 Protein protein interactors of human gene RHOT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RHOT2 (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D IEI001145 Protein protein interactors of human gene ATXN2L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATXN2L (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D IEI004361 Protein protein interactors of human gene EXOSC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EXOSC1 (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D TAX017094 GO:0008156 biological process negative regulation of DNA replication Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication. (more detail) 34 NA Homo sapiens

GOA MOX014519 Genes associated with Computational Drug Signature piceatannol Genes associated with Computational Drug Signature piceatannol, curated by the Drug Signature Databa (more detail) 34 25990557 Homo sapiens

DSigDB WIG000208 Genes related to CD40 signaling na (more detail) 34 NA Homo sapiens

MSigDB WIG001565 Inhibition of Matrix Metalloproteinases Inhibition of Matrix Metalloproteinases (more detail) 34 NA Homo sapiens

Protein Lounge MEX002394 Genes associated with Kinase Inhibitor TG100 115 Genes associated with Kinase Inhibitor TG100-115, curated by the Drug Signature Database (DSigDB). (more detail) 34 25990557 Homo sapiens

DSigDB WIG000088 IL1 mediated signaling events (more detail) 34 NA Homo sapiens

MSigDB FEX002826 StemCell Matar04 45genes Table 6. Genes differentially expressed in A431 cells treated with gefitinib or cetuximab (more detail) 34 15475436 Homo sapiens

GeneSigDB WIG000117 Trk receptor signaling mediated by the MAPK pathway (more detail) 34 NA Homo sapiens

MSigDB TAX022680 GO:0034979 molecular function NAD dependent protein deacetylase activity Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD. (more detail) 18 NA Homo sapiens

GOA IEI000558 Protein protein interactors of human gene ANAPC16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC16 (SwissProt I (more detail) 18 17535438 Homo sapiens

I2D TAX035035 GO:2001057 biological process reactive nitrogen species metabolic process The chemical reactions and pathways involving a reactive nitrogen species. (more detail) 18 NA Homo sapiens

GOA TAX025694 GO:0046655 biological process folic acid metabolic process The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely (more detail) 18 NA Homo sapiens

GOA TAX017610 GO:0009219 biological process pyrimidine deoxyribonucleotide metabolic process The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of (more detail) 18 NA Homo sapiens

GOA TAX022544 GO:0034587 biological process piRNA metabolic process The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nuc (more detail) 18 NA Homo sapiens

GOA TAX023830 GO:0042423 biological process catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of any of a group of physiologically (more detail) 18 NA Homo sapiens

GOA TAX024187 GO:0043153 biological process entrainment of circadian clock by photoperiod The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and (more detail) 18 NA Homo sapiens

GOA IEI002666 Protein protein interactors of human gene CLOCK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLOCK (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI014239 Protein protein interactors of human gene TRIM35 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM35 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D TAX017045 GO:0008074 cellular component guanylate cyclase complex, soluble Complex that possesses guanylate cyclase activity and is not bound to a membrane. (more detail) 18 NA Homo sapiens

GOA TAX017495 GO:0009083 biological process branched chain amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched (more detail) 18 NA Homo sapiens

GOA TAX017747 GO:0009713 biological process catechol containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Cat (more detail) 18 NA Homo sapiens

GOA IEI007149 Protein protein interactors of human gene LARP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LARP4 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D TAX025002 GO:0045190 biological process isotype switching The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immuno (more detail) 18 NA Homo sapiens

GOA TAX017250 GO:0008409 molecular function 5' 3' exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues f (more detail) 18 NA Homo sapiens

GOA TAX030929 GO:0097602 molecular function cullin family protein binding Interacting selectively and non-covalently with any member of the cullin family, hydrophobic protein (more detail) 18 NA Homo sapiens

GOA WIG000320 METS affect on Macrophage Differentiation Terminal differentiation of cells is often accompanied by repression of cellular proliferation, sugg (more detail) 18 NA Homo sapiens

MSigDB TAX014304 GO:0002566 biological process somatic diversification of immune receptors via somatic mutation The process in which immune receptor genes are diversified through somatic mutation. (more detail) 18 NA Homo sapiens

GOA MEX002326 Genes associated with Kinase Inhibitor Kinome 858 Genes associated with Kinase Inhibitor Kinome_858, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB MEX001921 Genes associated with Kinase Inhibitor LRRK2 IN 1 Genes associated with Kinase Inhibitor LRRK2-IN-1, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB MEX002297 Genes associated with Kinase Inhibitor ( ) Epigallocatechin gallate Genes associated with Kinase Inhibitor (-)-Epigallocatechin gallate, curated by the Drug Signature D (more detail) 18 25990557 Homo sapiens

DSigDB MEX001999 Genes associated with Kinase Inhibitor Quizartinib Genes associated with Kinase Inhibitor Quizartinib, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB PEX000728 zf C4: Zinc finger, C4 type (two domains) In nearly all cases, this is the DNA binding domain of a nuclear hormone receptor. The alignment con (more detail) 18 NA Homo sapiens

Pfam TAX013563 GO:0000966 biological process RNA 5' end processing Any process involved in forming the mature 5' end of an RNA molecule. (more detail) 18 NA Homo sapiens

GOA MEX002032 Genes associated with Kinase Inhibitor Syk Inhibitor II Genes associated with Kinase Inhibitor Syk Inhibitor II, curated by the Drug Signature Database (DSi (more detail) 18 25990557 Homo sapiens

DSigDB MAX002049 Composition of the 2 MDa human TFTC complex containing KAT2A [GeneID=2648]. Transcription in eukaryotes is a tightly regulated, multistep process. Gene-specific transcriptional (more detail) 18 NA Homo sapiens

MSigDB WAG000906 Inactivation of APC/C via direct inhibition of the APC/C complex (more detail) 18 NA Homo sapiens

Reactome MEX002234 Genes associated with Kinase Inhibitor czc 25146 Genes associated with Kinase Inhibitor czc-25146, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB MEX002201 Genes associated with Kinase Inhibitor 405554 55 4 Genes associated with Kinase Inhibitor 405554-55-4, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB MOX013298 Genes associated with Computational Drug Signature KN 62 Genes associated with Computational Drug Signature KN-62, curated by the Drug Signature Database (DS (more detail) 18 25990557 Homo sapiens

DSigDB WIG001042 Genes involved in N glycan antennae elongation in the medial/trans Golgi (more detail) 18 NA Homo sapiens

MSigDB TAX016725 GO:0007004 biological process telomere maintenance via telomerase The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase. (more detail) 18 NA Homo sapiens

GOA TAX015857 GO:0005665 cellular component RNA polymerase II, core complex RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a m (more detail) 18 NA Homo sapiens

GOA PEX002478 JmjC: JmjC domain, hydroxylase The JmjC domain belongs to the Cupin superfamily 3. JmjC-domain proteins may be protein hydroxylases (more detail) 18 NA Homo sapiens

Pfam MOX015470 Genes associated with Computational Drug Signature teniposide Genes associated with Computational Drug Signature teniposide, curated by the Drug Signature Databas (more detail) 18 25990557 Homo sapiens

DSigDB TAX015215 GO:0004550 molecular function nucleoside diphosphate kinase activity Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. (more detail) 18 NA Homo sapiens

GOA TAX000941 Genes annotated by the GO term GO:0000119. A protein complex that enables the RNA polymerase II general RNA polymerase II transcription factor complex to react to transcriptional activator proteins; also enhances the level of basal transcription. (more detail) 18 NA Homo sapiens

MSigDB TAX001159 Genes annotated by the GO term GO:0004527. Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. (more detail) 18 NA Homo sapiens

MSigDB TAX001359 Genes annotated by the GO term GO:0008186. Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of RNA; drives another reaction. (more detail) 18 NA Homo sapiens

MSigDB MEX001286 Genes associated with Kinase Inhibitor Syk Inhibitor Genes associated with Kinase Inhibitor Syk Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 18 25990557 Homo sapiens

DSigDB WIG001250 Genes involved in Synthesis of PC (more detail) 18 NA Homo sapiens

MSigDB WIG000837 Genes involved in Fatty Acyl CoA Biosynthesis (more detail) 18 NA Homo sapiens

MSigDB WAG000628 atm signaling pathway The ataxia telangiectasia-mutated gene (ATM) encodes a protein kise that acts as a tumor suppressor. (more detail) 18 NA Homo sapiens

BioCarta WIG000443 Telomeres, Telomerase, Cellular Aging, and Immortality Telomeres, which define the ends of chromosomes, consist of short, tandemly repeated DNA sequences l (more detail) 18 NA Homo sapiens

MSigDB TAX001144 Genes annotated by the GO term GO:0034061. Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and primer. (more detail) 18 NA Homo sapiens

MSigDB TAX000789 Genes annotated by the GO term GO:0006383. The synthesis of RNA from a DNA template by RNA polymerase III (Pol III), originating at a Pol III specific promoter. (more detail) 18 NA Homo sapiens

MSigDB MAX000052 Delayed early genes (DEG) which are coordinately down regulated in multiple epithelial tumor types. Signaling pathways invoke interplays between forward signaling and feedback to drive robust cellular (more detail) 18 NA Homo sapiens

MSigDB TAX013675 GO:0001522 biological process pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscrip (more detail) 18 NA Homo sapiens

GOA TAX015107 GO:0004383 molecular function guanylate cyclase activity Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate. (more detail) 18 NA Homo sapiens

GOA TAX014116 GO:0002208 biological process somatic diversification of immunoglobulins involved in immune response The somatic process that results in the generation of sequence diversity of immunoglobulins after in (more detail) 18 NA Homo sapiens

GOA MOX014670 Genes associated with Computational Drug Signature purvalanol A Genes associated with Computational Drug Signature purvalanol A, curated by the Drug Signature Datab (more detail) 18 25990557 Homo sapiens

DSigDB TAX016443 GO:0006577 biological process amino acid betaine metabolic process The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino ac (more detail) 18 NA Homo sapiens

GOA MEX002303 Genes associated with Kinase Inhibitor Kinome 1901 Genes associated with Kinase Inhibitor Kinome_1901, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB MEX002371 Genes associated with Kinase Inhibitor Kinome 454 Genes associated with Kinase Inhibitor Kinome_454, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB MEX002295 Genes associated with Kinase Inhibitor NVP TAE684 Genes associated with Kinase Inhibitor NVP-TAE684, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB PEX000443 BTB: BTB/POZ domain The BTB (for BR-C, ttk and bab) 1 or POZ (for Pox virus and Zinc finger) 2 domain is present near th (more detail) 18 NA Homo sapiens

Pfam TAX014115 GO:0002204 biological process somatic recombination of immunoglobulin genes involved in immune response The process in which immunoglobulin genes are formed through recombination of the germline genetic e (more detail) 18 NA Homo sapiens

GOA TAX014065 GO:0002097 biological process tRNA wobble base modification The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptiona (more detail) 18 NA Homo sapiens

GOA WIG000989 Genes involved in MicroRNA (miRNA) Biogenesis (more detail) 18 NA Homo sapiens

MSigDB MOX006902 Genes associated with Computational Drug Signature Alitretinoin Genes associated with Computational Drug Signature Alitretinoin, curated by the Drug Signature Datab (more detail) 18 25990557 Homo sapiens

DSigDB FOX000431 Genes in the cancer module 102 (more detail) 18 NA Homo sapiens

MSigDB TAX016145 GO:0006119 biological process oxidative phosphorylation The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operati (more detail) 18 NA Homo sapiens

GOA WIG000992 Genes involved in Mitochondrial tRNA aminoacylation (more detail) 18 NA Homo sapiens

MSigDB IEI002316 Protein protein interactors of human gene CELF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CELF1 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI001239 Protein protein interactors of human gene BAZ1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BAZ1A (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI008785 Protein protein interactors of human gene NFE2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFE2 (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D IEI015150 Protein protein interactors of human gene YEATS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YEATS2 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D TAX025684 GO:0046639 biological process negative regulation of alpha beta T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell diff (more detail) 24 NA Homo sapiens

GOA IEI001019 Protein protein interactors of human gene ATF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATF6 (SwissProt ID=P (more detail) 24 17535438 Homo sapiens

I2D IEI006767 Protein protein interactors of human gene KDM5C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM5C (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI004642 Protein protein interactors of human gene FBXO3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO3 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI005970 Protein protein interactors of human gene HOXA9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXA9 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI004326 Protein protein interactors of human gene ETV1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ETV1 (SwissProt ID=P (more detail) 24 17535438 Homo sapiens

I2D IEI000339 Protein protein interactors of human gene AFF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AFF4 (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D IEI004280 Protein protein interactors of human gene ERN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERN1 (SwissProt ID=O (more detail) 24 17535438 Homo sapiens

I2D IEI005788 Protein protein interactors of human gene HELLS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HELLS (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D TAX017737 GO:0009649 biological process entrainment of circadian clock The synchronization of a circadian rhythm to environmental time cues such as light. (more detail) 24 NA Homo sapiens

GOA IEI015173 Protein protein interactors of human gene YTHDF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YTHDF1 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D WIG000851 Genes involved in G0 and Early G1 (more detail) 24 NA Homo sapiens

MSigDB FEX000682 Breast Burga09 25genes Table 2. Selected genes and pathways that are differentially expressed between BRCA1-mutated and nor (more detail) 24 19190334 Homo sapiens

GeneSigDB MEX001111 Genes associated with Approved Drug carfilzomib Genes associated with Approved Drug carfilzomib, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB MOX016778 Genes associated with Computational Drug Signature Quinomycin A Genes associated with Computational Drug Signature Quinomycin A, curated by the Drug Signature Datab (more detail) 24 25990557 Homo sapiens

DSigDB WIG000072 Signaling events mediated by HDAC Class III (more detail) 24 NA Homo sapiens

MSigDB WIG001593 nNOS Signaling at Neuronal Synapses nNOS Signaling at Neuronal Synapses (more detail) 24 NA Homo sapiens

Protein Lounge WIG000616 Selenoamino acid metabolism (more detail) 24 NA Homo sapiens

MSigDB MOX000893 Genes associated with Computational Drug Signature Mitonafide Genes associated with Computational Drug Signature Mitonafide, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens

DSigDB WIG000329 Cell Cycle: G2/M Checkpoint The G2/M DNA damage checkpoint prevents the cell from entering mitosis (M phase) if the genome is da (more detail) 24 NA Homo sapiens

MSigDB IEI003341 Protein protein interactors of human gene DCAF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCAF8 (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D TAX032148 GO:1901532 biological process regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differenti (more detail) 36 NA Homo sapiens

GOA FOX000069 Neighborhood of RAD21 Neighborhood of RAD21 RAD21 homolog (S. pombe) in the GCM expression compendium (more detail) 36 NA Homo sapiens

MSigDB MOX001690 Genes associated with Computational Drug Signature Destruxin B Genes associated with Computational Drug Signature Destruxin B, curated by the Drug Signature Databa (more detail) 36 25990557 Homo sapiens

DSigDB FEX002652 Prostate Ma06 42genes Table 1. Genes differentially expressed by MAK-KR overexpression in LNCaP cells (more detail) 36 16951154 Homo sapiens

GeneSigDB WIG001075 Genes involved in PI3K/AKT activation (more detail) 36 NA Homo sapiens

MSigDB WIG000857 Genes involved in GAB1 signalosome (more detail) 36 NA Homo sapiens

MSigDB WIG001700 TNFR1 Pathway TNFR1 Pathway (more detail) 36 NA Homo sapiens

Protein Lounge MOX000105 Genes associated with Computational Drug Signature TAXIFOLIN Genes associated with Computational Drug Signature TAXIFOLIN, curated by the Drug Signature Database (more detail) 36 25990557 Homo sapiens

DSigDB MOX003860 Genes associated with Computational Drug Signature ciprofloxacin Genes associated with Computational Drug Signature ciprofloxacin, curated by the Drug Signature Data (more detail) 36 25990557 Homo sapiens

DSigDB MOX000510 Genes associated with Computational Drug Signature trolox Genes associated with Computational Drug Signature trolox, curated by the Drug Signature Database (D (more detail) 36 25990557 Homo sapiens

DSigDB MOX004194 Genes associated with Computational Drug Signature Luronit Genes associated with Computational Drug Signature Luronit, curated by the Drug Signature Database ( (more detail) 36 25990557 Homo sapiens

DSigDB IEI009248 Protein protein interactors of human gene OGDH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OGDH (SwissProt ID=Q (more detail) 29 17535438 Homo sapiens

I2D TAX021737 GO:0032728 biological process positive regulation of interferon beta production Any process that activates or increases the frequency, rate, or extent of interferon-beta production (more detail) 29 NA Homo sapiens

GOA IEI013636 Protein protein interactors of human gene TGIF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TGIF1 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D FAX003053 GSEA Hallmark Lung Cancer Tissue Explants (Extracellular Vesicles) G2M Checkpoint Top 3 pathways enriched in lung cancer tissue extract extracellular vesicle particles compared to ma (more detail) 29 32795414 Homo sapiens

Cell IEI005246 Protein protein interactors of human gene GLI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLI1 (SwissProt ID=P (more detail) 29 17535438 Homo sapiens

I2D IEI013071 Protein protein interactors of human gene STAG2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAG2 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI010736 Protein protein interactors of human gene PTPN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTPN2 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D TAX033643 GO:1904837 biological process beta catenin TCF complex assembly The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF (more detail) 29 NA Homo sapiens

GOA IEI010756 Protein protein interactors of human gene PTPRK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTPRK (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D TAX001191 Genes annotated by the GO term GO:0051427. Interacting selectively with a receptor for hormones. (more detail) 29 NA Homo sapiens

MSigDB FEX002233 Lymphoma Satoh05 30genes Tcells Table 2 Top 30 genes expressed differentially in T cells between MS and controls (more detail) 29 15755681 Homo sapiens

GeneSigDB MOX004998 Genes associated with Computational Drug Signature Cladribine Genes associated with Computational Drug Signature Cladribine, curated by the Drug Signature Databas (more detail) 29 25990557 Homo sapiens

DSigDB MAX002149 Genes up regulated in K562 cells (bone marrow) after treatment with dasatinib [PubChem=3062316] or imatinib [PubChem=5291]. Dasatinib is an ATP-competitive, multi-targeted SRC and ABL kinase inhibitor that can bind BCR-ABL i (more detail) 29 NA Homo sapiens

MSigDB WIG001913 miRs in Muscle Cell Differentiation miRs in Muscle Cell Differentiation (more detail) 29 NA Homo sapiens

WikiPathway MOX013135 Genes associated with Computational Drug Signature INDIRUBIN 3' MONOXIME Genes associated with Computational Drug Signature INDIRUBIN-3'-MONOXIME, curated by the Drug Signat (more detail) 29 25990557 Homo sapiens

DSigDB WIG001975 MAPK Cascade MAPK Cascade (more detail) 29 NA Homo sapiens

WikiPathway WEX000027 ERBB2 Signaling The genes related to erbb2 signaling (signaling pathways) in tumor using next-generation sequencer ( (more detail) 21 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas TAX023689 GO:0042135 biological process neurotransmitter catabolic process The chemical reactions and pathways resulting in the breakdown of any of a group of substances that (more detail) 21 NA Homo sapiens

GOA TAX019139 GO:0016638 molecular function oxidoreductase activity, acting on the CH NH2 group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or e (more detail) 21 NA Homo sapiens

GOA TAX035018 GO:2001032 biological process regulation of double strand break repair via nonhomologous end joining Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomolo (more detail) 21 NA Homo sapiens

GOA TAX027772 GO:0060261 biological process positive regulation of transcription initiation from RNA polymerase II promoter Any process that increases the rate, frequency or extent of a process involved in starting transcrip (more detail) 21 NA Homo sapiens

GOA TAX017300 GO:0008483 molecular function transaminase activity Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid. (more detail) 21 NA Homo sapiens

GOA IEI005987 Protein protein interactors of human gene HOXC8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXC8 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI011398 Protein protein interactors of human gene RNF144B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF144B (SwissProt I (more detail) 21 17535438 Homo sapiens

I2D IEI012075 Protein protein interactors of human gene SETX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SETX (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI006403 Protein protein interactors of human gene INO80C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INO80C (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D TAX021234 GO:0031935 biological process regulation of chromatin silencing Any process that affects the rate, extent or location of chromatin silencing. (more detail) 21 NA Homo sapiens

GOA IEI006428 Protein protein interactors of human gene INTS10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS10 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI011894 Protein protein interactors of human gene SCYL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCYL2 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI001651 Protein protein interactors of human gene C7orf50 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C7orf50 (SwissProt I (more detail) 21 17535438 Homo sapiens

I2D WIG000827 Genes involved in ERK/MAPK targets (more detail) 21 NA Homo sapiens

MSigDB MOX007549 Genes associated with Computational Drug Signature Cdk9 Inhibitor II Genes associated with Computational Drug Signature Cdk9 Inhibitor II, curated by the Drug Signature (more detail) 21 25990557 Homo sapiens

DSigDB FOX000697 Genes in the cancer module 4 (more detail) 21 NA Homo sapiens

MSigDB TAX000291 Genes annotated by the GO term GO:0030522. Any series of molecular signals initiated by a ligand entering the target cell, where it binds to an intracellular receptor. (more detail) 21 NA Homo sapiens

MSigDB MOX003392 Genes associated with Computational Drug Signature salubrinal Genes associated with Computational Drug Signature salubrinal, curated by the Drug Signature Databas (more detail) 21 25990557 Homo sapiens

DSigDB WIG000844 Genes involved in Formation of incision complex in GG NER (more detail) 21 NA Homo sapiens

MSigDB TAX000767 Genes annotated by the GO term GO:0000245. The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. (more detail) 21 NA Homo sapiens

MSigDB MOX000907 Genes associated with Computational Drug Signature POTASSIUM BROMATE Genes associated with Computational Drug Signature POTASSIUM BROMATE, curated by the Drug Signature (more detail) 21 25990557 Homo sapiens

DSigDB WAG001622 Taurine and hypotaurine metabolism (more detail) 21 NA Homo sapiens

KEGG WAG001341 RNA Polymerase III Transcription Initiation From Type 1 Promoter (more detail) 21 NA Homo sapiens

Reactome MAX000760 Genes in the blue cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. Breast cancer is a heterogeneous disease made of various molecular subtypes with different prognosis (more detail) 21 NA Homo sapiens

MSigDB MOX003294 Genes associated with Computational Drug Signature purvalanol A Genes associated with Computational Drug Signature purvalanol A, curated by the Drug Signature Datab (more detail) 21 25990557 Homo sapiens

DSigDB WIG000531 Glycosaminoglycan degradation (more detail) 21 NA Homo sapiens

MSigDB IEI010803 Protein protein interactors of human gene PYCR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PYCR1 (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D TAX034125 GO:1905953 biological process negative regulation of lipid localization Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization. (more detail) 38 NA Homo sapiens

GOA TAX024392 GO:0043491 biological process protein kinase B signaling A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also (more detail) 38 NA Homo sapiens

GOA IEI003580 Protein protein interactors of human gene DLAT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLAT (SwissProt ID=P (more detail) 38 17535438 Homo sapiens

I2D IEI007672 Protein protein interactors of human gene MAP4K1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP4K1 (SwissProt ID (more detail) 38 17535438 Homo sapiens

I2D IEI001855 Protein protein interactors of human gene CBLC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CBLC (SwissProt ID=Q (more detail) 38 17535438 Homo sapiens

I2D WAG001435 Lysine degradation (more detail) 38 NA Homo sapiens

KEGG MOX003320 Genes associated with Computational Drug Signature Dacinostat Genes associated with Computational Drug Signature Dacinostat, curated by the Drug Signature Databas (more detail) 38 25990557 Homo sapiens

DSigDB WAG000616 Notch signaling pathway The Notch sigling pathway is an evolutiorily conserved, intercellular sigling mechanism essential fo (more detail) 38 NA Homo sapiens

KEGG FEX009019 hsa miR 425 3p HITS-CLIP, Functional MTI (Weak) (more detail) 38 NA Homo sapiens

mirTARbase MOX016481 Genes associated with Computational Drug Signature cantharidin Genes associated with Computational Drug Signature cantharidin, curated by the Drug Signature Databa (more detail) 38 25990557 Homo sapiens

DSigDB WIG001952 FAS pathway and Stress induction of HSP regulation FAS pathway and Stress induction of HSP regulation (more detail) 38 NA Homo sapiens

WikiPathway IEI000867 Protein protein interactors of human gene ARIH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARIH1 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D IEI012634 Protein protein interactors of human gene SMNDC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMNDC1 (SwissProt ID (more detail) 40 17535438 Homo sapiens

I2D TAX028251 GO:0061014 biological process positive regulation of mRNA catabolic process Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical (more detail) 40 NA Homo sapiens

GOA IEI012614 Protein protein interactors of human gene SMG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMG1 (SwissProt ID=Q (more detail) 40 17535438 Homo sapiens

I2D WEX000098 TH17 Differentiation The genes related to th17 differentiation (adaptive immunity) in immune using next-generation sequen (more detail) 40 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI007466 Protein protein interactors of human gene LSM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSM1 (SwissProt ID=O (more detail) 40 17535438 Homo sapiens

I2D MOX001004 Genes associated with Computational Drug Signature Pregna 4,17(20) diene 3,16 dione Genes associated with Computational Drug Signature Pregna-4,17(20)-diene-3,16-dione, curated by the (more detail) 40 25990557 Homo sapiens

DSigDB MOX005159 Genes associated with Computational Drug Signature Equol Genes associated with Computational Drug Signature Equol, curated by the Drug Signature Database (DS (more detail) 40 25990557 Homo sapiens

DSigDB IEI004764 Protein protein interactors of human gene FH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FH (SwissProt ID=P07 (more detail) 42 17535438 Homo sapiens

I2D IEI012051 Protein protein interactors of human gene SERTAD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERTAD1 (SwissProt I (more detail) 42 17535438 Homo sapiens

I2D MOX001631 Genes associated with Computational Drug Signature Allyl sulfide Genes associated with Computational Drug Signature Allyl sulfide, curated by the Drug Signature Data (more detail) 42 25990557 Homo sapiens

DSigDB MOX003773 Genes associated with Computational Drug Signature 2,6 Di tert butyl 4 methylphenol Genes associated with Computational Drug Signature 2,6-Di-tert-butyl-4-methylphenol, curated by the (more detail) 42 25990557 Homo sapiens

DSigDB TAX000609 Genes annotated by the GO term GO:0000079. Any process that modulates the frequency, rate or extent of CDK activity. (more detail) 42 NA Homo sapiens

MSigDB MOX012010 Genes associated with Computational Drug Signature clioquinol Genes associated with Computational Drug Signature clioquinol, curated by the Drug Signature Databas (more detail) 42 25990557 Homo sapiens

DSigDB MEX000821 Genes associated with Approved Drug sorafenib tosylate Genes associated with Approved Drug sorafenib tosylate, curated by the Drug Signature Database (DSig (more detail) 42 25990557 Homo sapiens

DSigDB IEI002570 Protein protein interactors of human gene CISH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CISH (SwissProt ID=Q (more detail) 31 17535438 Homo sapiens

I2D IEI004315 Protein protein interactors of human gene ETF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ETF1 (SwissProt ID=P (more detail) 31 17535438 Homo sapiens

I2D IEI014345 Protein protein interactors of human gene TSC22D3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TSC22D3 (SwissProt I (more detail) 31 17535438 Homo sapiens

I2D TAX030569 GO:0090568 cellular component nuclear transcriptional repressor complex A protein complex, located in the nucleus, that possesses activity that prevents or downregulates tr (more detail) 31 NA Homo sapiens

GOA IEI006192 Protein protein interactors of human gene IFNAR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFNAR1 (SwissProt ID (more detail) 31 17535438 Homo sapiens

I2D IEI006900 Protein protein interactors of human gene KLF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF6 (SwissProt ID=Q (more detail) 31 17535438 Homo sapiens

I2D IEI001884 Protein protein interactors of human gene CCAR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCAR1 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI004074 Protein protein interactors of human gene ELAC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELAC2 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D WIG001016 Genes involved in Negative regulators of RIG I/MDA5 signaling (more detail) 31 NA Homo sapiens

MSigDB MOX002189 Genes associated with Computational Drug Signature Microcystin LR Genes associated with Computational Drug Signature Microcystin LR, curated by the Drug Signature Dat (more detail) 31 25990557 Homo sapiens

DSigDB MOX001611 Genes associated with Computational Drug Signature Cryptotanshinone Genes associated with Computational Drug Signature Cryptotanshinone, curated by the Drug Signature D (more detail) 31 25990557 Homo sapiens

DSigDB IEI014557 Protein protein interactors of human gene UBAP2L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBAP2L (SwissProt ID (more detail) 44 17535438 Homo sapiens

I2D IEI011442 Protein protein interactors of human gene RNF40 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF40 (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D IEI010415 Protein protein interactors of human gene PQBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PQBP1 (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D IEI015016 Protein protein interactors of human gene WDR6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR6 (SwissProt ID=Q (more detail) 44 17535438 Homo sapiens

I2D IEI000969 Protein protein interactors of human gene ASCC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASCC2 (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D IEI007166 Protein protein interactors of human gene LBR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LBR (SwissProt ID=Q1 (more detail) 44 17535438 Homo sapiens

I2D TAX021459 GO:0032330 biological process regulation of chondrocyte differentiation Any process that modulates the frequency, rate or extent of chondrocyte differentiation. (more detail) 44 NA Homo sapiens

GOA IEI014973 Protein protein interactors of human gene WBP11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WBP11 (SwissProt ID= (more detail) 44 17535438 Homo sapiens

I2D MOX007169 Genes associated with Computational Drug Signature baicalein Genes associated with Computational Drug Signature baicalein, curated by the Drug Signature Database (more detail) 44 25990557 Homo sapiens

DSigDB FEX000198 Brain Lastowska07 49genes Table 3. Genes identified in this study previously implicated in cancer (more detail) 44 17533364 Homo sapiens

GeneSigDB MEX001194 Genes associated with Approved Drug methacycline hydrochloride Genes associated with Approved Drug methacycline hydrochloride, curated by the Drug Signature Databa (more detail) 44 25990557 Homo sapiens

DSigDB FEX001425 Leukemia Wilson06 50genes DifferentialClusterD Table S2.4. Genes with differential expression patterns between VxInsight cluster D and the rest of (more detail) 44 16597596 Homo sapiens

GeneSigDB FEX000440 Breast Chalabi06 57genes Table 2.p-value for each gene modulated by lycopene treatment for MCF-7 MDA-MB-231 and MCF-10a cell (more detail) 44 16886892 Homo sapiens

GeneSigDB MAX002625 Cluster 5: genes changed in primary keratinocytes by UVB irradiation. UV radiation is the most important environmental skin aggressor, causing cancer and other problems. (more detail) 46 NA Homo sapiens

MSigDB FEX003194 Stomach Yuan04 54genes Table 2. Genes related to cell cycle cell death and proliferation. More than 300 genes altered thei (more detail) 46 15358818 Homo sapiens

GeneSigDB MOX004178 Genes associated with Computational Drug Signature Ferriheme chloride Genes associated with Computational Drug Signature Ferriheme chloride, curated by the Drug Signature (more detail) 46 25990557 Homo sapiens

DSigDB TAX021021 GO:0031491 molecular function nucleosome binding Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound aroun (more detail) 46 NA Homo sapiens

GOA IEI009941 Protein protein interactors of human gene PIM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIM1 (SwissProt ID=P (more detail) 46 17535438 Homo sapiens

I2D IEI005661 Protein protein interactors of human gene H2AZ2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AZ2 (SwissProt ID= (more detail) 46 17535438 Homo sapiens

I2D WEX000021 DNA Sensing The genes related to dna sensing (innate immunity) in tumor using next-generation sequencer (NGS) re (more detail) 46 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI007733 Protein protein interactors of human gene MASP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MASP1 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D TAX028125 GO:0060765 biological process regulation of androgen receptor signaling pathway Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway (more detail) 26 NA Homo sapiens

GOA IEI007947 Protein protein interactors of human gene MGA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MGA (SwissProt ID=Q8 (more detail) 26 17535438 Homo sapiens

I2D IEI013352 Protein protein interactors of human gene TAF5L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF5L (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D WIG000003 ALK1 signaling events (more detail) 26 NA Homo sapiens

MSigDB WAG000817 Pantothenate and CoA biosynthesis (more detail) 26 NA Homo sapiens

KEGG WIG000588 Pentose phosphate pathway The pentose phosphate pathway is a process of glucose turnover that produces NADPH as reducing equiv (more detail) 26 NA Homo sapiens

MSigDB MOX004412 Genes associated with Computational Drug Signature nicotinamide Genes associated with Computational Drug Signature nicotinamide, curated by the Drug Signature Datab (more detail) 26 25990557 Homo sapiens

DSigDB WAG000225 angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling Ang II binding to AT1-R triggers the activation of Ca2+ sigling and PKC. The sigl is then transmitt (more detail) 26 NA Homo sapiens

BioCarta WIG001233 Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (more detail) 26 NA Homo sapiens

MSigDB TAX000723 Genes annotated by the GO term GO:0009411. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. (more detail) 26 NA Homo sapiens

MSigDB MOX016346 Genes associated with Computational Drug Signature 4 aminophenol Genes associated with Computational Drug Signature 4-aminophenol, curated by the Drug Signature Data (more detail) 26 25990557 Homo sapiens

DSigDB MOX004607 Genes associated with Computational Drug Signature pyrimethamine Genes associated with Computational Drug Signature pyrimethamine, curated by the Drug Signature Data (more detail) 26 25990557 Homo sapiens

DSigDB TAX026313 GO:0048713 biological process regulation of oligodendrocyte differentiation Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation. (more detail) 33 NA Homo sapiens

GOA IEI006146 Protein protein interactors of human gene ID1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ID1 (SwissProt ID=P4 (more detail) 33 17535438 Homo sapiens

I2D IEI011073 Protein protein interactors of human gene RBM17 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM17 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI014023 Protein protein interactors of human gene TNFSF11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNFSF11 (SwissProt I (more detail) 33 17535438 Homo sapiens

I2D IEI005815 Protein protein interactors of human gene HEXIM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HEXIM1 (SwissProt ID (more detail) 33 17535438 Homo sapiens

I2D IEI006634 Protein protein interactors of human gene KAT6A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KAT6A (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI014929 Protein protein interactors of human gene VPS72 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VPS72 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI001171 Protein protein interactors of human gene AXL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AXL (SwissProt ID=P3 (more detail) 33 17535438 Homo sapiens

I2D IEI015028 Protein protein interactors of human gene WDR83 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR83 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D MOX000389 Genes associated with Computational Drug Signature Myricitrin Genes associated with Computational Drug Signature Myricitrin, curated by the Drug Signature Databas (more detail) 33 25990557 Homo sapiens

DSigDB TAX000331 Genes annotated by the GO term GO:0051321. Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell. (more detail) 33 NA Homo sapiens

MSigDB MOX001883 Genes associated with Computational Drug Signature AH 23848 Genes associated with Computational Drug Signature AH 23848, curated by the Drug Signature Database (more detail) 33 25990557 Homo sapiens

DSigDB MOX017657 Genes associated with Computational Drug Signature FENRETINIDE Genes associated with Computational Drug Signature FENRETINIDE, curated by the Drug Signature Databa (more detail) 33 25990557 Homo sapiens

DSigDB IEI003778 Protein protein interactors of human gene DR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DR1 (SwissProt ID=Q0 (more detail) 35 17535438 Homo sapiens

I2D IEI009650 Protein protein interactors of human gene PDCD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDCD4 (SwissProt ID= (more detail) 35 17535438 Homo sapiens

I2D TAX029661 GO:0071774 biological process response to fibroblast growth factor Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 35 NA Homo sapiens

GOA TAX022216 GO:0033692 biological process cellular polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (more detail) 35 NA Homo sapiens

GOA TAX016715 GO:0006984 biological process ER nucleus signaling pathway Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucle (more detail) 35 NA Homo sapiens

GOA IEI011255 Protein protein interactors of human gene RGS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RGS3 (SwissProt ID=P (more detail) 35 17535438 Homo sapiens

I2D IEI013920 Protein protein interactors of human gene TMEM33 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TMEM33 (SwissProt ID (more detail) 35 17535438 Homo sapiens

I2D IEI010231 Protein protein interactors of human gene POLR3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR3A (SwissProt ID (more detail) 35 17535438 Homo sapiens

I2D WAG001267 TNF receptor signaling pathway (more detail) 35 NA Homo sapiens

NCI-Nature Curated IEI004251 Protein protein interactors of human gene ERCC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERCC4 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI005328 Protein protein interactors of human gene GNL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GNL2 (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D IEI006196 Protein protein interactors of human gene IFNG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFNG (SwissProt ID=P (more detail) 23 17535438 Homo sapiens

I2D IEI002344 Protein protein interactors of human gene CENPS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CENPS (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI013359 Protein protein interactors of human gene TAF9B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF9B (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI006977 Protein protein interactors of human gene KMT5A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KMT5A (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D TAX031709 GO:0140103 molecular function catalytic activity, acting on a glycoprotein catalytic activity, acting on a glycosylated protein (more detail) 23 NA Homo sapiens

GOA IEI004252 Protein protein interactors of human gene ERCC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERCC5 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D TAX032321 GO:1901984 biological process negative regulation of protein acetylation Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation. (more detail) 23 NA Homo sapiens

GOA WIG000398 Hypoxia and p53 in the Cardiovascular system Hypoxic stress, like DNA damage, induces p53 protein accumulation and p53-dependent apoptosis in onc (more detail) 23 NA Homo sapiens

MSigDB MOX001149 Genes associated with Computational Drug Signature 4 aminophenol Genes associated with Computational Drug Signature 4-aminophenol, curated by the Drug Signature Data (more detail) 23 25990557 Homo sapiens

DSigDB MOX003861 Genes associated with Computational Drug Signature citrinin Genes associated with Computational Drug Signature citrinin, curated by the Drug Signature Database (more detail) 23 25990557 Homo sapiens

DSigDB TAX014040 GO:0002067 biological process glandular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glandular ep (more detail) 23 NA Homo sapiens

GOA MOX001793 Genes associated with Computational Drug Signature FLAVONE Genes associated with Computational Drug Signature FLAVONE, curated by the Drug Signature Database ( (more detail) 23 25990557 Homo sapiens

DSigDB WIG000700 Genes involved in APC Cdc20 mediated degradation of Nek2A (more detail) 23 NA Homo sapiens

MSigDB WAG001277 Canonical NF kappaB pathway (more detail) 23 NA Homo sapiens

NCI-Nature Curated TAX025837 GO:0046966 molecular function thyroid hormone receptor binding Interacting selectively and non-covalently with a thyroid hormone receptor. (more detail) 28 NA Homo sapiens

GOA TAX032639 GO:1902751 biological process positive regulation of cell cycle G2/M phase transition Any process that activates or increases the frequency, rate or extent of cell cycle G2/M phase trans (more detail) 28 NA Homo sapiens

GOA IEI010510 Protein protein interactors of human gene PRMT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRMT2 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI009125 Protein protein interactors of human gene NUAK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUAK1 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI001275 Protein protein interactors of human gene BCL11A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCL11A (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D IEI006337 Protein protein interactors of human gene IL24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL24 (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI001817 Protein protein interactors of human gene CASP14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASP14 (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D IEI014957 Protein protein interactors of human gene WAPL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WAPL (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI001809 Protein protein interactors of human gene CASC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASC3 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D TAX028265 GO:0061036 biological process positive regulation of cartilage development Any process that increases the rate, frequency, or extent of cartilage development, the process whos (more detail) 28 NA Homo sapiens

GOA IEI003302 Protein protein interactors of human gene DAPK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DAPK3 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI009743 Protein protein interactors of human gene PELI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PELI1 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D FOX000602 Genes in the cancer module 281 (more detail) 28 NA Homo sapiens

MSigDB FOX000201 Neighborhood of RPA1 Neighborhood of RPA1 replication protein A1, 70kDa in the GNF2 expression compendium (more detail) 28 NA Homo sapiens

MSigDB MAX001667 Genes up regulated in Wilm's tumor vs fetal kidney. Anaplasia (unfavorable histology) is associated with therapy resistance and poor prognosis of Wilms (more detail) 28 NA Homo sapiens

MSigDB WIG000328 Cell Cycle: G1/S Check Point The G1/S cell cycle checkpoint controls the passage of eukaryotic cells from the first 'gap' phase ( (more detail) 28 NA Homo sapiens

MSigDB TAX001267 Genes annotated by the GO term GO:0035257. Interacting selectively with a nuclear hormone receptor, a ligand dependent receptor found in the nucleus of the cell. (more detail) 28 NA Homo sapiens

MSigDB TAX024493 GO:0043649 biological process dicarboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic ac (more detail) 17 NA Homo sapiens

GOA IEI000864 Protein protein interactors of human gene ARID4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARID4B (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D TAX020196 GO:0022624 cellular component proteasome accessory complex A protein complex, that caps one or both ends of the proteasome core complex and regulates entry int (more detail) 17 NA Homo sapiens

GOA IEI008864 Protein protein interactors of human gene NKX2 5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NKX2-5 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI009017 Protein protein interactors of human gene NR0B1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR0B1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI010278 Protein protein interactors of human gene POU2F2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POU2F2 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI005583 Protein protein interactors of human gene GTF2H2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2H2 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI014251 Protein protein interactors of human gene TRIM46 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM46 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI001209 Protein protein interactors of human gene BACH2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BACH2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX029248 GO:0071005 cellular component U2 type precatalytic spliceosome A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to t (more detail) 17 NA Homo sapiens

GOA TAX022914 GO:0035518 biological process histone H2A monoubiquitination The modification of histone H2A by addition of a single ubiquitin group. (more detail) 17 NA Homo sapiens

GOA TAX019031 GO:0016446 biological process somatic hypermutation of immunoglobulin genes Mutations occurring somatically that result in amino acid changes in the rearranged V regions of imm (more detail) 17 NA Homo sapiens

GOA TAX018853 GO:0016074 biological process snoRNA metabolic process The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small R (more detail) 17 NA Homo sapiens

GOA TAX027262 GO:0051923 biological process sulfation The addition of a sulfate group to a molecule. (more detail) 17 NA Homo sapiens

GOA TAX022751 GO:0035173 molecular function histone kinase activity Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-so (more detail) 17 NA Homo sapiens

GOA TAX024011 GO:0042772 biological process DNA damage response, signal transduction resulting in transcription A cascade of processes initiated in response to the detection of DNA damage, and resulting in the in (more detail) 17 NA Homo sapiens

GOA TAX024026 GO:0042800 molecular function histone methyltransferase activity (H3 K4 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L (more detail) 17 NA Homo sapiens

GOA TAX018809 GO:0015985 biological process energy coupled proton transport, down electrochemical gradient The transport of protons across a membrane to generate an electrochemical gradient (proton-motive fo (more detail) 17 NA Homo sapiens

GOA TAX017218 GO:0008353 molecular function RNA polymerase II CTD heptapeptide repeat kinase activity Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA (more detail) 17 NA Homo sapiens

GOA TAX016980 GO:0007597 biological process blood coagulation, intrinsic pathway A protein activation cascade that contributes to blood coagulation and consists of the interactions (more detail) 17 NA Homo sapiens

GOA TAX023476 GO:0038061 biological process NIK/NF kappaB signaling The process in which a signal is passed on to downstream components within the cell through the NIK- (more detail) 17 NA Homo sapiens

GOA TAX024200 GO:0043174 biological process nucleoside salvage Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucl (more detail) 17 NA Homo sapiens

GOA IEI011123 Protein protein interactors of human gene RCAN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RCAN1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI013191 Protein protein interactors of human gene SUDS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUDS3 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX017592 GO:0009200 biological process deoxyribonucleoside triphosphate metabolic process The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consist (more detail) 17 NA Homo sapiens

GOA TAX018810 GO:0015986 biological process ATP synthesis coupled proton transport The transport of protons across a membrane to generate an electrochemical gradient (proton-motive fo (more detail) 17 NA Homo sapiens

GOA TAX018821 GO:0016018 molecular function cyclosporin A binding Interacting selectively and non-covalently with cyclosporin A, a cyclic undecapeptide that contains (more detail) 17 NA Homo sapiens

GOA TAX019197 GO:0016755 molecular function transferase activity, transferring amino acyl groups Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). (more detail) 17 NA Homo sapiens

GOA TAX026454 GO:0050435 biological process amyloid beta metabolic process The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer (more detail) 17 NA Homo sapiens

GOA TAX025494 GO:0046209 biological process nitric oxide metabolic process The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas (more detail) 17 NA Homo sapiens

GOA TAX019144 GO:0016646 molecular function oxidoreductase activity, acting on the CH NH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or el (more detail) 17 NA Homo sapiens

GOA TAX025407 GO:0046037 biological process GMP metabolic process The chemical reactions and pathways involving GMP, guanosine monophosphate. (more detail) 17 NA Homo sapiens

GOA IEI011407 Protein protein interactors of human gene RNF166 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF166 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D TAX017486 GO:0009070 biological process serine family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the serine family, (more detail) 17 NA Homo sapiens

GOA MEX000868 Genes associated with Approved Drug alitretinoin Genes associated with Approved Drug alitretinoin, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB TAX016392 GO:0006525 biological process arginine metabolic process The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. (more detail) 17 NA Homo sapiens

GOA TAX013571 GO:0000979 molecular function RNA polymerase II core promoter sequence specific DNA binding Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of (more detail) 17 NA Homo sapiens

GOA PEX002548 Helicase C: Helicase conserved C terminal domain The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide (more detail) 17 NA Homo sapiens

Pfam WAG001293 APC/C:Cdc20 mediated degradation of Cyclin B (more detail) 17 NA Homo sapiens

Reactome WIG001596 NTHi Induced Signaling NTHi-Induced Signaling (more detail) 17 NA Homo sapiens

Protein Lounge WIG000657 Genes involved in activated TAK1 mediates p38 MAPK activation (more detail) 17 NA Homo sapiens

MSigDB WIG001165 Genes involved in RNA Polymerase III Chain Elongation (more detail) 17 NA Homo sapiens

MSigDB MEX001699 Genes associated with Kinase Inhibitor GW806742X Genes associated with Kinase Inhibitor GW806742X, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB TAX001093 Genes annotated by the GO term GO:0004004. Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of an RNA helix. (more detail) 17 NA Homo sapiens

MSigDB WIG000945 Genes involved in Intrinsic Pathway (more detail) 17 NA Homo sapiens

MSigDB WIG001455 Complement Pathway Complement Pathway (more detail) 17 NA Homo sapiens

Protein Lounge MEX001654 Genes associated with Kinase Inhibitor CHEMBL2062936 Genes associated with Kinase Inhibitor CHEMBL2062936, curated by the Drug Signature Database (DSigDB (more detail) 17 25990557 Homo sapiens

DSigDB TAX015858 GO:0005666 cellular component RNA polymerase III complex RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a (more detail) 17 NA Homo sapiens

GOA FOX000659 Genes in the cancer module 349 (more detail) 17 NA Homo sapiens

MSigDB MEX002171 Genes associated with Kinase Inhibitor PF 03814735 Genes associated with Kinase Inhibitor PF-03814735, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB MEX001852 Genes associated with Kinase Inhibitor PD166285 Genes associated with Kinase Inhibitor PD166285, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB WIG001193 Genes involved in SHC related events (more detail) 17 NA Homo sapiens

MSigDB WIG001966 Mitochondrial Gene Expression Mitochondrial Gene Expression (more detail) 17 NA Homo sapiens

WikiPathway TAX013709 GO:0001573 biological process ganglioside metabolic process The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to othe (more detail) 17 NA Homo sapiens

GOA MOX014380 Genes associated with Computational Drug Signature PD 173074 Genes associated with Computational Drug Signature PD 173074, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens

DSigDB WIG000206 The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. na (more detail) 17 NA Homo sapiens

MSigDB MEX002318 Genes associated with Kinase Inhibitor GW801372X Genes associated with Kinase Inhibitor GW801372X, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB TAX013250 GO:0000097 biological process sulfur amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, com (more detail) 17 NA Homo sapiens

GOA WIG000794 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) (more detail) 17 NA Homo sapiens

MSigDB MEX001560 Genes associated with Kinase Inhibitor TWS119 Genes associated with Kinase Inhibitor TWS119, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB MEX001909 Genes associated with Kinase Inhibitor gw8510 Genes associated with Kinase Inhibitor gw8510, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB WAG000483 Intrinsic Pathway (more detail) 17 NA Homo sapiens

Reactome MEX001683 Genes associated with Kinase Inhibitor Kinome 452 Genes associated with Kinase Inhibitor Kinome_452, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB TAX013394 GO:0000400 molecular function four way junction DNA binding Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Hol (more detail) 17 NA Homo sapiens

GOA TAX013428 GO:0000460 biological process maturation of 5.8S rRNA Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a matu (more detail) 17 NA Homo sapiens

GOA FEX002223 Lymphoma Guedez05 17genes Table 2. Changes in B-cell transcription regulators (more detail) 17 15479729 Homo sapiens

GeneSigDB WIG000339 Human Cytomegalovirus and Map Kinase Pathways To replicate in the host cell, viruses commandeer cellular signaling pathways. Cytomegalovirus (CMV) (more detail) 17 NA Homo sapiens

MSigDB WIG000576 One carbon pool by folate (more detail) 17 NA Homo sapiens

MSigDB IEI011608 Protein protein interactors of human gene RPS6KA6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS6KA6 (SwissProt I (more detail) 37 17535438 Homo sapiens

I2D IEI015371 Protein protein interactors of human gene ZMYND11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZMYND11 (SwissProt I (more detail) 37 17535438 Homo sapiens

I2D IEI003536 Protein protein interactors of human gene DHX16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHX16 (SwissProt ID= (more detail) 37 17535438 Homo sapiens

I2D IEI011745 Protein protein interactors of human gene S100A7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene S100A7 (SwissProt ID (more detail) 37 17535438 Homo sapiens

I2D IEI009714 Protein protein interactors of human gene PDS5A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDS5A (SwissProt ID= (more detail) 37 17535438 Homo sapiens

I2D WIG000255 ALK in cardiac myocytes Heart formation is cued by a combination of positive and negative signals from surrounding tissues. (more detail) 37 NA Homo sapiens

MSigDB MOX004278 Genes associated with Computational Drug Signature malathion Genes associated with Computational Drug Signature malathion, curated by the Drug Signature Database (more detail) 37 25990557 Homo sapiens

DSigDB FOX000181 Neighborhood of NS Neighborhood of NS NULL in the GNF2 expression compendium (more detail) 37 NA Homo sapiens

MSigDB IEI000976 Protein protein interactors of human gene ASF1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASF1B (SwissProt ID= (more detail) 39 17535438 Homo sapiens

I2D IEI009392 Protein protein interactors of human gene OXSR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OXSR1 (SwissProt ID= (more detail) 39 17535438 Homo sapiens

I2D IEI011410 Protein protein interactors of human gene RNF169 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF169 (SwissProt ID (more detail) 39 17535438 Homo sapiens

I2D TAX021839 GO:0032881 biological process regulation of polysaccharide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 39 NA Homo sapiens

GOA IEI003557 Protein protein interactors of human gene DIMT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIMT1 (SwissProt ID= (more detail) 39 17535438 Homo sapiens

I2D MOX017791 Genes associated with Computational Drug Signature suramin Genes associated with Computational Drug Signature suramin, curated by the Drug Signature Database ( (more detail) 39 25990557 Homo sapiens

DSigDB MAX000517 Supplementary Table 2. Genelist comparing microarray expression profiles of spermatogonial cells, haGSCs and hES (H1) cells. Examples of expression rates of different hES cell enriched and germ cell specific genes, surface markers for germ cell selection and signal transduction in all three cell types (spermatogonial cells = SC). Human primordial germ cells and mouse neonatal and adult germline stem cells are pluripotent and sho (more detail) 39 NA Homo sapiens

MSigDB FOX000171 Neighborhood of MLH1 Neighborhood of MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) in the GNF2 expres (more detail) 39 NA Homo sapiens

MSigDB MAX000902 Cluster d8: genes progressively down regulated in WS1 cells (fibroblast) through 18 h after irradiation with high dose UV C. DNA damage caused by UV radiation initiates cellular recovery mechanisms, which involve activation o (more detail) 39 NA Homo sapiens

MSigDB MOX016991 Genes associated with Computational Drug Signature geldanamycin Genes associated with Computational Drug Signature geldanamycin, curated by the Drug Signature Datab (more detail) 39 25990557 Homo sapiens

DSigDB MOX005115 Genes associated with Computational Drug Signature 1,6,7,8,9,11a,12,13,14,14a Decahydro 1,13 dihydroxy 6 methyl 4H cyclopent [f]oxacyclotridecin 4 one Genes associated with Computational Drug Signature 1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydro (more detail) 39 25990557 Homo sapiens

DSigDB IEI009996 Protein protein interactors of human gene PKNOX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PKNOX1 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI011192 Protein protein interactors of human gene REV1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene REV1 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI004867 Protein protein interactors of human gene FOXG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXG1 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX021389 GO:0032211 biological process negative regulation of telomere maintenance via telomerase Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telome (more detail) 20 NA Homo sapiens

GOA IEI010190 Protein protein interactors of human gene POLB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLB (SwissProt ID=P (more detail) 20 17535438 Homo sapiens

I2D TAX016766 GO:0007063 biological process regulation of sister chromatid cohesion Any process that modulates the frequency, rate or extent of sister chromatid cohesion. (more detail) 20 NA Homo sapiens

GOA TAX015881 GO:0005697 cellular component telomerase holoenzyme complex Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a cataly (more detail) 20 NA Homo sapiens

GOA WAG001342 RNA Polymerase III Transcription Initiation From Type 2 Promoter (more detail) 20 NA Homo sapiens

Reactome TAX000769 Genes annotated by the GO term GO:0030518. Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor. (more detail) 20 NA Homo sapiens

MSigDB WIG001453 CMV and MAPK Pathways CMV and MAPK Pathways (more detail) 20 NA Homo sapiens

Protein Lounge WAG000908 RNA Polymerase III Transcription Initiation (more detail) 20 NA Homo sapiens

Reactome WIG001734 Mechanism of Anthrax Toxins Mechanism of Anthrax Toxins (more detail) 20 NA Homo sapiens

Protein Lounge WAG000416 nfkb activation by nontypeable hemophilus influenzae The role of Hemophilus influenzae in ear infections and chronic obstructive pulmory disease includes (more detail) 20 NA Homo sapiens

BioCarta TAX013646 GO:0001223 molecular function transcription coactivator binding Interacting selectively and non-covalently with a transcription coactivator, any protein involved in (more detail) 20 NA Homo sapiens

GOA TAX015874 GO:0005686 cellular component U2 snRNP A ribonucleoprotein complex that contains small nuclear RNA U2. (more detail) 20 NA Homo sapiens

GOA TAX015885 GO:0005719 cellular component nuclear euchromatin The dispersed less dense form of chromatin in the interphase nucleus. It exists in at least two form (more detail) 20 NA Homo sapiens

GOA WIG001177 Genes involved in RNA Polymerase I Transcription Termination (more detail) 20 NA Homo sapiens

MSigDB WAG000237 fas signaling pathway (cd95) Ras activates many sigling cascades. Here we illustrate some of the well-characterized cascades in (more detail) 20 NA Homo sapiens

BioCarta WIG000835 Genes involved in Fanconi Anemia pathway (more detail) 20 NA Homo sapiens

MSigDB WIG001135 Genes involved in Regulation of gene expression in beta cells (more detail) 20 NA Homo sapiens

MSigDB TAX000261 Genes annotated by the GO term GO:0048872. The biological processes involved in the maintenance of the equilibrium of cell number within a population of cells. (more detail) 20 NA Homo sapiens

MSigDB WAG000410 role of erbb2 in signal transduction and oncology Her2 or ERBB2 belongs to a class of proteins having high homology with epidermal growth factor recep (more detail) 20 NA Homo sapiens

BioCarta TAX001197 Genes annotated by the GO term GO:0016811. Catalysis of the hydrolysis of any non peptide carbon nitrogen bond in a linear amide. (more detail) 20 NA Homo sapiens

MSigDB IEI013140 Protein protein interactors of human gene STOML2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STOML2 (SwissProt ID (more detail) 41 17535438 Homo sapiens

I2D TAX014035 GO:0002062 biological process chondrocyte differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a (more detail) 41 NA Homo sapiens

GOA MOX003638 Genes associated with Computational Drug Signature Salbutamol Genes associated with Computational Drug Signature Salbutamol, curated by the Drug Signature Databas (more detail) 41 25990557 Homo sapiens

DSigDB WIG000290 Regulation And Function Of ChREBP in Liver Liver is the major site for carbohydrate metabolism (glycolysis and glycogen synthesis) and triglyce (more detail) 41 NA Homo sapiens

MSigDB TAX013810 GO:0001756 biological process somitogenesis The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis (more detail) 41 NA Homo sapiens

GOA MAX001717 Up regulated genes discriminating multiple myeloma samples by the ype of immunoglobulin light chain they produce: Ig lambda (IGLL) vs Ig kappa (IGLK). Although multiple myeloma (MM) is a unique entity, a marked heterogeneity is actually observed among (more detail) 41 NA Homo sapiens

MSigDB TAX021487 GO:0032371 biological process regulation of sterol transport Any process that modulates the frequency, rate or extent of the directed movement of sterols into, o (more detail) 43 NA Homo sapiens

GOA IEI002578 Protein protein interactors of human gene CKAP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CKAP4 (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D IEI012559 Protein protein interactors of human gene SLIRP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLIRP (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D MOX004539 Genes associated with Computational Drug Signature pimozide Genes associated with Computational Drug Signature pimozide, curated by the Drug Signature Database (more detail) 43 25990557 Homo sapiens

DSigDB TAX021490 GO:0032374 biological process regulation of cholesterol transport Any process that modulates the frequency, rate or extent of the directed movement of cholesterol int (more detail) 43 NA Homo sapiens

GOA MOX016566 Genes associated with Computational Drug Signature clioquinol Genes associated with Computational Drug Signature clioquinol, curated by the Drug Signature Databas (more detail) 43 25990557 Homo sapiens

DSigDB IEI007349 Protein protein interactors of human gene LONP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LONP1 (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D IEI007755 Protein protein interactors of human gene MBD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MBD1 (SwissProt ID=Q (more detail) 43 17535438 Homo sapiens

I2D MAX002754 Genes up regulated in MCF10A cells (breast cancer) by expression of LSM1 [GeneID=27257] off a letiviral vector. Amplification of the 8p11-12 region occurs in 15-20% of breast cancers, but the driving oncogene at (more detail) 43 NA Homo sapiens

MSigDB TAX021831 GO:0032873 biological process negative regulation of stress activated MAPK cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction me (more detail) 43 NA Homo sapiens

GOA TAX028856 GO:0070303 biological process negative regulation of stress activated protein kinase signaling cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stre (more detail) 43 NA Homo sapiens

GOA IEI003037 Protein protein interactors of human gene CSDE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSDE1 (SwissProt ID= (more detail) 43 17535438 Homo sapiens

I2D IEI008806 Protein protein interactors of human gene NFX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFX1 (SwissProt ID=Q (more detail) 43 17535438 Homo sapiens

I2D IEI013447 Protein protein interactors of human gene TBL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBL2 (SwissProt ID=Q (more detail) 30 17535438 Homo sapiens

I2D TAX029063 GO:0070670 biological process response to interleukin 4 Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 30 NA Homo sapiens

GOA IEI005085 Protein protein interactors of human gene GATAD2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GATAD2A (SwissProt I (more detail) 30 17535438 Homo sapiens

I2D IEI011674 Protein protein interactors of human gene RTF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RTF1 (SwissProt ID=Q (more detail) 30 17535438 Homo sapiens

I2D IEI011643 Protein protein interactors of human gene RRP7A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRP7A (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D IEI014060 Protein protein interactors of human gene TNRC6A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNRC6A (SwissProt ID (more detail) 30 17535438 Homo sapiens

I2D TAX027524 GO:0055007 biological process cardiac muscle cell differentiation The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac musc (more detail) 30 NA Homo sapiens

GOA WIG001433 CD40 Signaling CD40 Signaling (more detail) 30 NA Homo sapiens

Protein Lounge WAG000828 nfat and hypertrophy of the heart Hypertrophy associated with both hypertension and obstruction to ventricular outflow leads to pathol (more detail) 30 NA Homo sapiens

BioCarta WIG000153 Regulation of Ras family activation (more detail) 30 NA Homo sapiens

MSigDB MOX004445 Genes associated with Computational Drug Signature OLEANOLIC ACID Genes associated with Computational Drug Signature OLEANOLIC ACID, curated by the Drug Signature Dat (more detail) 30 25990557 Homo sapiens

DSigDB WIG000322 FAS signaling pathway ( CD95 ) Receptors in the TNF receptor family are associated with the induction of apoptosis, as well as infl (more detail) 30 NA Homo sapiens

MSigDB MOX007474 Genes associated with Computational Drug Signature cantharidin Genes associated with Computational Drug Signature cantharidin, curated by the Drug Signature Databa (more detail) 30 25990557 Homo sapiens

DSigDB IEI010316 Protein protein interactors of human gene PPIH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPIH (SwissProt ID=O (more detail) 25 17535438 Homo sapiens

I2D IEI010192 Protein protein interactors of human gene POLD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLD2 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI011096 Protein protein interactors of human gene RBM5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM5 (SwissProt ID=P (more detail) 25 17535438 Homo sapiens

I2D MOX004137 Genes associated with Computational Drug Signature Crystal violet Genes associated with Computational Drug Signature Crystal violet, curated by the Drug Signature Dat (more detail) 25 25990557 Homo sapiens

DSigDB WIG001501 AHR Pathway AHR Pathway (more detail) 25 NA Homo sapiens

Protein Lounge TAX000130 Genes annotated by the GO term GO:0006338. Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. (more detail) 25 NA Homo sapiens

MSigDB WAG000646 cell cycle: g1/s check point The G1/S cell cycle checkpoint controls the passage of eukaryotic cells from the first 'gap' phase ( (more detail) 25 NA Homo sapiens

BioCarta WIG001249 Genes involved in Synthesis of PA (more detail) 25 NA Homo sapiens

MSigDB MOX012365 Genes associated with Computational Drug Signature dl Thioctic acid Genes associated with Computational Drug Signature dl-Thioctic acid, curated by the Drug Signature D (more detail) 25 25990557 Homo sapiens

DSigDB IEI003040 Protein protein interactors of human gene CSF1R from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSF1R (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D IEI001062 Protein protein interactors of human gene ATP1A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP1A2 (SwissProt ID (more detail) 32 17535438 Homo sapiens

I2D MOX003843 Genes associated with Computational Drug Signature chloroquine Genes associated with Computational Drug Signature chloroquine, curated by the Drug Signature Databa (more detail) 32 25990557 Homo sapiens

DSigDB TAX001120 Genes annotated by the GO term GO:0003682. Interacting selectively with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. (more detail) 32 NA Homo sapiens

MSigDB MOX001181 Genes associated with Computational Drug Signature Benzyl butyl phthalate Genes associated with Computational Drug Signature Benzyl butyl phthalate, curated by the Drug Signa (more detail) 34 25990557 Homo sapiens

DSigDB MOX017372 Genes associated with Computational Drug Signature N Stearoyl D sphingosine Genes associated with Computational Drug Signature N-Stearoyl-D-sphingosine, curated by the Drug Sig (more detail) 34 25990557 Homo sapiens

DSigDB TAX000821 Genes annotated by the GO term GO:0022415. A reproductive process involved in viral reproduction. Usually, this is by infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle. (more detail) 34 NA Homo sapiens

MSigDB IEI003504 Protein protein interactors of human gene DGCR8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DGCR8 (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D IEI005508 Protein protein interactors of human gene GRIN2D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRIN2D (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D IEI001852 Protein protein interactors of human gene CBFB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CBFB (SwissProt ID=Q (more detail) 34 17535438 Homo sapiens

I2D IEI009750 Protein protein interactors of human gene PEPD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PEPD (SwissProt ID=P (more detail) 34 17535438 Homo sapiens

I2D TAX033028 GO:1903580 biological process positive regulation of ATP metabolic process Any process that activates or increases the frequency, rate or extent of ATP metabolic process. (more detail) 34 NA Homo sapiens

GOA IEI015201 Protein protein interactors of human gene ZBTB17 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB17 (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D IEI003361 Protein protein interactors of human gene DCP1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCP1A (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D TAX019928 GO:0021515 biological process cell differentiation in spinal cord The process in which relatively unspecialized cells acquire specialized structural and/or functional (more detail) 34 NA Homo sapiens

GOA IEI005647 Protein protein interactors of human gene H2AC11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AC11 (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D IEI008210 Protein protein interactors of human gene MRPL41 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPL41 (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D TAX022474 GO:0034405 biological process response to fluid shear stress Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 34 NA Homo sapiens

GOA IEI006898 Protein protein interactors of human gene KLF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF4 (SwissProt ID=O (more detail) 34 17535438 Homo sapiens

I2D IEI005688 Protein protein interactors of human gene HABP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HABP4 (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D TAX018296 GO:0014014 biological process negative regulation of gliogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the forma (more detail) 36 NA Homo sapiens

GOA IEI007563 Protein protein interactors of human gene MAD2L2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAD2L2 (SwissProt ID (more detail) 36 17535438 Homo sapiens

I2D IEI007702 Protein protein interactors of human gene MAPKAPK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPKAPK3 (SwissProt (more detail) 36 17535438 Homo sapiens

I2D IEI011409 Protein protein interactors of human gene RNF168 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF168 (SwissProt ID (more detail) 36 17535438 Homo sapiens

I2D IEI004071 Protein protein interactors of human gene EIF5B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF5B (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D MEX000610 Genes associated with Approved Drug raloxifene hydrochloride Genes associated with Approved Drug raloxifene hydrochloride, curated by the Drug Signature Database (more detail) 36 25990557 Homo sapiens

DSigDB MOX017106 Genes associated with Computational Drug Signature methyldopa Genes associated with Computational Drug Signature methyldopa, curated by the Drug Signature Databas (more detail) 36 25990557 Homo sapiens

DSigDB TAX013687 GO:0001541 biological process ovarian follicle development The process whose specific outcome is the progression of the ovarian follicle over time, from its fo (more detail) 36 NA Homo sapiens

GOA IEI002251 Protein protein interactors of human gene CDK2AP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK2AP1 (SwissProt I (more detail) 27 17535438 Homo sapiens

I2D IEI005593 Protein protein interactors of human gene GTF3C2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF3C2 (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D TAX022740 GO:0035116 biological process embryonic hindlimb morphogenesis The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are genera (more detail) 27 NA Homo sapiens

GOA IEI009832 Protein protein interactors of human gene PHC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHC1 (SwissProt ID=P (more detail) 27 17535438 Homo sapiens

I2D IEI011563 Protein protein interactors of human gene RPP38 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPP38 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI001850 Protein protein interactors of human gene CBFA2T2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CBFA2T2 (SwissProt I (more detail) 27 17535438 Homo sapiens

I2D IEI009659 Protein protein interactors of human gene PDE12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDE12 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI008541 Protein protein interactors of human gene NACC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NACC1 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI014230 Protein protein interactors of human gene TRIM26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM26 (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D FOX000098 Neighborhood of BUB3 Neighborhood of BUB3 BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) in the GNF2 expre (more detail) 27 NA Homo sapiens

MSigDB WAG000859 Osteopontin mediated events (more detail) 27 NA Homo sapiens

NCI-Nature Curated WIG001437 Cell Cycle Control by BTG Proteins Cell Cycle Control by BTG Proteins (more detail) 27 NA Homo sapiens

Protein Lounge MOX001951 Genes associated with Computational Drug Signature Evodiamine Genes associated with Computational Drug Signature Evodiamine, curated by the Drug Signature Databas (more detail) 27 25990557 Homo sapiens

DSigDB TAX016276 GO:0006359 biological process regulation of transcription by RNA polymerase III Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase (more detail) 27 NA Homo sapiens

GOA TAX017736 GO:0009648 biological process photoperiodism Any process that results in a change in state or activity of an organism (in terms of movement, secr (more detail) 22 NA Homo sapiens

GOA IEI005818 Protein protein interactors of human gene HEY2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HEY2 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI010959 Protein protein interactors of human gene RAI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAI1 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D TAX019305 GO:0016922 molecular function nuclear receptor binding Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor pr (more detail) 22 NA Homo sapiens

GOA IEI015254 Protein protein interactors of human gene ZC3HC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZC3HC1 (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D IEI004807 Protein protein interactors of human gene FLI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FLI1 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI007743 Protein protein interactors of human gene MATK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MATK (SwissProt ID=P (more detail) 22 17535438 Homo sapiens

I2D IEI003936 Protein protein interactors of human gene EDF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EDF1 (SwissProt ID=O (more detail) 22 17535438 Homo sapiens

I2D TAX034868 GO:2000679 biological process positive regulation of transcription regulatory region DNA binding Any process that activates or increases the frequency, rate or extent of transcription regulatory re (more detail) 22 NA Homo sapiens

GOA TAX026453 GO:0050434 biological process positive regulation of viral transcription Any process that activates or increases the frequency, rate or extent of viral transcription. (more detail) 22 NA Homo sapiens

GOA WAG001236 links between pyk2 and map kinases This diagram is a compilation of Pyk2 effort cascades. In specific cell types the receptor and effo (more detail) 22 NA Homo sapiens

BioCarta WIG000358 IL 6 signaling pathway Interleukin-6 (IL-6) is a cytokine that provokes a broad range of cellular and physiological respons (more detail) 22 NA Homo sapiens

MSigDB TAX013575 GO:0000983 molecular function transcription factor activity, RNA polymerase II core promoter sequence specific DNA binding Interacting selectively and non-covalently with a specific DNA sequence in an RNA polymerase II (Pol (more detail) 22 NA Homo sapiens

GOA MOX014632 Genes associated with Computational Drug Signature PROPIDIUM Genes associated with Computational Drug Signature PROPIDIUM, curated by the Drug Signature Database (more detail) 22 25990557 Homo sapiens

DSigDB WAG001343 RNA Polymerase III Transcription Initiation From Type 3 Promoter (more detail) 22 NA Homo sapiens

Reactome MOX003236 Genes associated with Computational Drug Signature Sirtinol Genes associated with Computational Drug Signature Sirtinol, curated by the Drug Signature Database (more detail) 22 25990557 Homo sapiens

DSigDB MOX002445 Genes associated with Computational Drug Signature Clofarabine Genes associated with Computational Drug Signature Clofarabine, curated by the Drug Signature Databa (more detail) 22 25990557 Homo sapiens

DSigDB MOX001617 Genes associated with Computational Drug Signature Baicalin Genes associated with Computational Drug Signature Baicalin, curated by the Drug Signature Database (more detail) 22 25990557 Homo sapiens

DSigDB MOX002098 Genes associated with Computational Drug Signature Garcinol Genes associated with Computational Drug Signature Garcinol, curated by the Drug Signature Database (more detail) 22 25990557 Homo sapiens

DSigDB WIG000130 Canonical NF kappaB pathway (more detail) 22 NA Homo sapiens

MSigDB MOX015586 Genes associated with Computational Drug Signature Tozasertib Genes associated with Computational Drug Signature Tozasertib, curated by the Drug Signature Databas (more detail) 22 25990557 Homo sapiens

DSigDB MOX004033 Genes associated with Computational Drug Signature Quinomycin A Genes associated with Computational Drug Signature Quinomycin A, curated by the Drug Signature Datab (more detail) 22 25990557 Homo sapiens

DSigDB WIG000254 AKT Signaling Pathway Many cell-surface receptors induce production of second messengers like PIP3, phosphatidylinositol 3 (more detail) 22 NA Homo sapiens

MSigDB MOX016019 Genes associated with Computational Drug Signature Isotretinoin Genes associated with Computational Drug Signature Isotretinoin, curated by the Drug Signature Datab (more detail) 22 25990557 Homo sapiens

DSigDB IEI002240 Protein protein interactors of human gene CDK11B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK11B (SwissProt ID (more detail) 38 17535438 Homo sapiens

I2D IEI000119 Protein protein interactors of human gene ACAT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACAT2 (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D WIG001037 Genes involved in Nuclear signaling by ERBB4 (more detail) 38 NA Homo sapiens

MSigDB MOX009666 Genes associated with Computational Drug Signature CHEMBL332826 Genes associated with Computational Drug Signature CHEMBL332826, curated by the Drug Signature Datab (more detail) 38 25990557 Homo sapiens

DSigDB FOX000199 Neighborhood of RFC3 Neighborhood of RFC3 replication factor C (activator 1) 3, 38kDa in the GNF2 expression compendium (more detail) 38 NA Homo sapiens

MSigDB FEX003120 StemCell Mullighan09 39genes Supplementary Table 27. Genes driving negative enrichment of the B-cell signal transduction gene set (more detail) 38 19129520 Homo sapiens

GeneSigDB FEX000325 Breast Shen04 45genes UpRegulated Supp Table 7a. Meta-signature gene list. The excel file contains a list of Unigene ID gene symbol (more detail) 38 15598354 Homo sapiens

GeneSigDB TAX025145 GO:0045581 biological process negative regulation of T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation (more detail) 40 NA Homo sapiens

GOA IEI007793 Protein protein interactors of human gene MCM10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCM10 (SwissProt ID= (more detail) 40 17535438 Homo sapiens

I2D IEI000151 Protein protein interactors of human gene ACP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACP1 (SwissProt ID=P (more detail) 40 17535438 Homo sapiens

I2D IEI002796 Protein protein interactors of human gene COL1A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COL1A2 (SwissProt ID (more detail) 40 17535438 Homo sapiens

I2D IEI014735 Protein protein interactors of human gene URI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene URI1 (SwissProt ID=O (more detail) 40 17535438 Homo sapiens

I2D WIG000636 Tyrosine metabolism (more detail) 40 NA Homo sapiens

MSigDB MOX016840 Genes associated with Computational Drug Signature Aziridine Genes associated with Computational Drug Signature Aziridine, curated by the Drug Signature Database (more detail) 40 25990557 Homo sapiens

DSigDB MOX014525 Genes associated with Computational Drug Signature pimozide Genes associated with Computational Drug Signature pimozide, curated by the Drug Signature Database (more detail) 40 25990557 Homo sapiens

DSigDB TAX014618 GO:0003179 biological process heart valve morphogenesis The process in which the structure of a heart valve is generated and organized. (more detail) 40 NA Homo sapiens

GOA MOX003303 Genes associated with Computational Drug Signature Sunitinib Genes associated with Computational Drug Signature Sunitinib, curated by the Drug Signature Database (more detail) 40 25990557 Homo sapiens

DSigDB MOX005015 Genes associated with Computational Drug Signature linolenic acid Genes associated with Computational Drug Signature linolenic acid, curated by the Drug Signature Dat (more detail) 40 25990557 Homo sapiens

DSigDB WIG000216 B Cell Antigen Receptor na (more detail) 40 NA Homo sapiens

MSigDB TAX030179 GO:0080111 biological process DNA demethylation The removal of a methyl group from one or more nucleotides within an DNA molecule. (more detail) 16 NA Homo sapiens

GOA TAX024154 GO:0043101 biological process purine containing compound salvage Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or n (more detail) 16 NA Homo sapiens

GOA TAX028683 GO:0070008 molecular function serine type exopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus (more detail) 16 NA Homo sapiens

GOA TAX015326 GO:0004697 molecular function protein kinase C activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylgl (more detail) 16 NA Homo sapiens

GOA IEI013475 Protein protein interactors of human gene TCEAL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCEAL2 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX018435 GO:0015012 biological process heparan sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, (more detail) 16 NA Homo sapiens

GOA TAX026206 GO:0048531 molecular function beta 1,3 galactosyltransferase activity Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, formin (more detail) 16 NA Homo sapiens

GOA IEI004598 Protein protein interactors of human gene FBH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBH1 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI011156 Protein protein interactors of human gene RECQL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RECQL4 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX016711 GO:0006978 biological process DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent prot (more detail) 16 NA Homo sapiens

GOA TAX029186 GO:0070918 biological process production of small RNA involved in gene silencing by RNA The process in which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. R (more detail) 16 NA Homo sapiens

GOA TAX019500 GO:0018216 biological process peptidyl arginine methylation The addition of a methyl group to an arginine residue in a protein. (more detail) 16 NA Homo sapiens

GOA TAX019626 GO:0019198 molecular function transmembrane receptor protein phosphatase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to in (more detail) 16 NA Homo sapiens

GOA TAX015543 GO:0005001 molecular function transmembrane receptor protein tyrosine phosphatase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to in (more detail) 16 NA Homo sapiens

GOA IEI003055 Protein protein interactors of human gene CSN1S1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSN1S1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI006404 Protein protein interactors of human gene INO80D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INO80D (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX022003 GO:0033151 biological process V(D)J recombination The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specifi (more detail) 16 NA Homo sapiens

GOA TAX022514 GO:0034471 biological process ncRNA 5' end processing Any process involved in forming the mature 5' end of a non-coding RNA molecule. (more detail) 16 NA Homo sapiens

GOA TAX016268 GO:0006349 biological process regulation of gene expression by genetic imprinting Heritable alterations in the activity of a gene that depend on whether it passed through the paterna (more detail) 16 NA Homo sapiens

GOA TAX024082 GO:0042982 biological process amyloid precursor protein metabolic process The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyl (more detail) 16 NA Homo sapiens

GOA TAX023895 GO:0042559 biological process pteridine containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of any compound containing pteridine (more detail) 16 NA Homo sapiens

GOA TAX019229 GO:0016805 molecular function dipeptidase activity Catalysis of the hydrolysis of a dipeptide. (more detail) 16 NA Homo sapiens

GOA TAX019623 GO:0019184 biological process nonribosomal peptide biosynthetic process The biosynthetic process in which peptide bond formation occurs in the absence of the translational (more detail) 16 NA Homo sapiens

GOA TAX020774 GO:0031050 biological process dsRNA fragmentation Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (genera (more detail) 16 NA Homo sapiens

GOA IEI009505 Protein protein interactors of human gene PARP12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PARP12 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI004568 Protein protein interactors of human gene FANCE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FANCE (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX023177 GO:0035970 biological process peptidyl threonine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine. (more detail) 16 NA Homo sapiens

GOA TAX018458 GO:0015074 biological process DNA integration The process in which a segment of DNA is incorporated into another, usually larger, DNA molecule suc (more detail) 16 NA Homo sapiens

GOA TAX017600 GO:0009208 biological process pyrimidine ribonucleoside triphosphate metabolic process The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound con (more detail) 16 NA Homo sapiens

GOA IEI006286 Protein protein interactors of human gene IKZF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IKZF4 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX023670 GO:0042107 biological process cytokine metabolic process The chemical reactions and pathways involving cytokines, any of a group of proteins or glycoproteins (more detail) 16 NA Homo sapiens

GOA TAX019401 GO:0017136 molecular function NAD dependent histone deacetylase activity Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This react (more detail) 16 NA Homo sapiens

GOA IEI015183 Protein protein interactors of human gene YY1AP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YY1AP1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI002734 Protein protein interactors of human gene CNOT4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNOT4 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI004405 Protein protein interactors of human gene FAAP24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAAP24 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI011281 Protein protein interactors of human gene RHOBTB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RHOBTB1 (SwissProt I (more detail) 16 17535438 Homo sapiens

I2D IEI011640 Protein protein interactors of human gene RRP15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRP15 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI005967 Protein protein interactors of human gene HOXA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXA5 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX017936 GO:0010485 molecular function H4 histone acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4. (more detail) 16 NA Homo sapiens

GOA TAX019879 GO:0019908 cellular component nuclear cyclin dependent protein kinase holoenzyme complex Cyclin-dependent protein kinase (CDK) complex found in the nucleus. (more detail) 16 NA Homo sapiens

GOA TAX014881 GO:0003964 molecular function RNA directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes (more detail) 16 NA Homo sapiens

GOA IEI003090 Protein protein interactors of human gene CSTF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSTF1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX024192 GO:0043162 biological process ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently ta (more detail) 16 NA Homo sapiens

GOA TAX024548 GO:0043968 biological process histone H2A acetylation The modification of histone H2A by the addition of an acetyl group. (more detail) 16 NA Homo sapiens

GOA TAX023906 GO:0042575 cellular component DNA polymerase complex A protein complex that possesses DNA polymerase activity and is involved in template directed synthe (more detail) 16 NA Homo sapiens

GOA IEI009532 Protein protein interactors of human gene PAX5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAX5 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI005846 Protein protein interactors of human gene HINT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HINT1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI000198 Protein protein interactors of human gene ACTR8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACTR8 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D WAG000402 One carbon pool by folate (more detail) 16 NA Homo sapiens

KEGG WIG002005 Complement Activation, Classical Pathway Complement Activation, Classical Pathway (more detail) 16 NA Homo sapiens

WikiPathway TAX013384 GO:0000380 biological process alternative mRNA splicing, via spliceosome The process of generating multiple mRNA molecules from a given set of exons by differential use of e (more detail) 16 NA Homo sapiens

GOA FEX000581 Breast Finetti08 16genes Table 1. List of the 16 kinases from the gene cluster identified byquality threshold-clustering (more detail) 16 18245477 Homo sapiens

GeneSigDB WIG000583 Pantothenate and CoA biosynthesis (more detail) 16 NA Homo sapiens

MSigDB TAX001361 Genes annotated by the GO term GO:0034062. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template. (more detail) 16 NA Homo sapiens

MSigDB MEX001336 Genes associated with Kinase Inhibitor Kinome 2010 Genes associated with Kinase Inhibitor Kinome_2010, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB MOX000280 Genes associated with Computational Drug Signature p Propenylanisole Genes associated with Computational Drug Signature p-Propenylanisole, curated by the Drug Signature (more detail) 16 25990557 Homo sapiens

DSigDB TAX016215 GO:0006266 biological process DNA ligation The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. (more detail) 16 NA Homo sapiens

GOA MAX000762 Genes in the green cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. Breast cancer is a heterogeneous disease made of various molecular subtypes with different prognosis (more detail) 16 NA Homo sapiens

MSigDB MAX000763 Genes in the red cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. Breast cancer is a heterogeneous disease made of various molecular subtypes with different prognosis (more detail) 16 NA Homo sapiens

MSigDB TAX001196 Genes annotated by the GO term GO:0016814. Catalysis of the hydrolysis of any non peptide carbon nitrogen bond in a cyclic amidine, a compound of the form R C(=NH) NH2. (more detail) 16 NA Homo sapiens

MSigDB TAX001186 Genes annotated by the GO term GO:0004402. Catalysis of the reaction: acetyl CoA + histone = CoA + acetyl histone. (more detail) 16 NA Homo sapiens

MSigDB WIG000042 DNA PK pathway in nonhomologous end joining (more detail) 16 NA Homo sapiens

MSigDB WIG000656 Genes involved in Activated point mutants of FGFR2 (more detail) 16 NA Homo sapiens

MSigDB WIG000954 Genes involved in JNK (c Jun kinases) phosphorylation and activation mediated by activated human TAK1 (more detail) 16 NA Homo sapiens

MSigDB MEX001310 Genes associated with Kinase Inhibitor Kinome 473 Genes associated with Kinase Inhibitor Kinome_473, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB TAX016519 GO:0006677 biological process glycosylceramide metabolic process The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacem (more detail) 16 NA Homo sapiens

GOA TAX001414 Genes annotated by the GO term GO:0016790. Catalysis of the reaction: RCO SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO SR'), such as that found in acetyl coenzyme A. (more detail) 16 NA Homo sapiens

MSigDB TAX000741 Genes annotated by the GO term GO:0016072. The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes. (more detail) 16 NA Homo sapiens

MSigDB MEX001440 Genes associated with Kinase Inhibitor Kinome 866 Genes associated with Kinase Inhibitor Kinome_866, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB TAX016411 GO:0006544 biological process glycine metabolic process The chemical reactions and pathways involving glycine, aminoethanoic acid. (more detail) 16 NA Homo sapiens

GOA TAX016458 GO:0006595 biological process polyamine metabolic process The chemical reactions and pathways involving polyamines, any organic compound containing two or mor (more detail) 16 NA Homo sapiens

GOA TAX013293 GO:0000176 cellular component nuclear exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuc (more detail) 16 NA Homo sapiens

GOA WIG000129 Atypical NF kappaB pathway (more detail) 16 NA Homo sapiens

MSigDB MEX002341 Genes associated with Kinase Inhibitor GW806290X Genes associated with Kinase Inhibitor GW806290X, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB WAG000423 human cytomegalovirus and map kinase pathways To replicate in the host cell, viruses commandeer cellular sigling pathways. Cytomegalovirus (CMV) i (more detail) 16 NA Homo sapiens

BioCarta WAG000509 Phosphorylation of the APC/C (more detail) 16 NA Homo sapiens

Reactome WIG002000 ID signaling pathway ID signaling pathway (more detail) 16 NA Homo sapiens

WikiPathway FEX001680 Leukemia Messina10 16genes Table 4. PK Genes Specifically Expressed in B-NEG Patients Versus at Least 2 Other Groups (more detail) 16 20564080 Homo sapiens

GeneSigDB TAX000332 Genes annotated by the GO term GO:0007131. The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity. (more detail) 16 NA Homo sapiens

MSigDB WIG000578 Other glycan degradation (more detail) 16 NA Homo sapiens

MSigDB MEX001468 Genes associated with Kinase Inhibitor Kinome 1242 Genes associated with Kinase Inhibitor Kinome_1242, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB MEX001830 Genes associated with Kinase Inhibitor CHEMBL463931 Genes associated with Kinase Inhibitor CHEMBL463931, curated by the Drug Signature Database (DSigDB) (more detail) 16 25990557 Homo sapiens

DSigDB MEX001867 Genes associated with Kinase Inhibitor HG 9 91 01 Genes associated with Kinase Inhibitor HG-9-91-01, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB WIG001140 Genes involved in Regulation of Insulin like Growth Factor (IGF) Activity by Insulin like Growth Factor Binding Proteins (IGFBPs) (more detail) 16 NA Homo sapiens

MSigDB MEX001349 Genes associated with Kinase Inhibitor CHEMBL1982466 Genes associated with Kinase Inhibitor CHEMBL1982466, curated by the Drug Signature Database (DSigDB (more detail) 16 25990557 Homo sapiens

DSigDB FOX000689 Genes in the cancer module 388 (more detail) 16 NA Homo sapiens

MSigDB WAG000074 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (more detail) 16 NA Homo sapiens

Reactome TAX031933 GO:1900408 biological process negative regulation of cellular response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to ox (more detail) 42 NA Homo sapiens

GOA IEI014727 Protein protein interactors of human gene UQCRC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UQCRC2 (SwissProt ID (more detail) 42 17535438 Homo sapiens

I2D TAX032835 GO:1903202 biological process negative regulation of oxidative stress induced cell death Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induce (more detail) 42 NA Homo sapiens

GOA IEI014751 Protein protein interactors of human gene USP10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP10 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D IEI008244 Protein protein interactors of human gene MRPS26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPS26 (SwissProt ID (more detail) 42 17535438 Homo sapiens

I2D IEI004029 Protein protein interactors of human gene EIF2B2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF2B2 (SwissProt ID (more detail) 42 17535438 Homo sapiens

I2D IEI013676 Protein protein interactors of human gene THOC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THOC6 (SwissProt ID= (more detail) 42 17535438 Homo sapiens

I2D MOX005067 Genes associated with Computational Drug Signature 9,12 Octadecadienoic acid Genes associated with Computational Drug Signature 9,12-Octadecadienoic acid, curated by the Drug Si (more detail) 42 25990557 Homo sapiens

DSigDB MAX002158 Genes up regulated in P493 6 cells (B lymphocyte, Burkitt's lymphoma model) by MYC [GeneID=4609] and down regulated by RNAi knockdown of TFRC [GeneID=7037]. Overexpression of transferrin receptor 1 (TFRC1), a major mediator of iron uptake in mammalian cells (more detail) 42 NA Homo sapiens

MSigDB FEX002339 Lymphoma Germinal07 77genes Table S8. Cell cycle gene set that best distinguishes ABC and GCB subgroup. (more detail) 42 19455257 Homo sapiens

GeneSigDB WAG000994 Fructose and mannose metabolism (more detail) 42 NA Homo sapiens

KEGG FEX002340 Lymphoma Germinal07 44genes Table S9. The cell cycle genes which were chosen to distinguish the ABC and the GCB group. (more detail) 42 19455257 Homo sapiens

GeneSigDB MOX003172 Genes associated with Computational Drug Signature PURPURIN Genes associated with Computational Drug Signature PURPURIN, curated by the Drug Signature Database (more detail) 42 25990557 Homo sapiens

DSigDB WIG000471 Amino sugar and nucleotide sugar metabolism (more detail) 42 NA Homo sapiens

MSigDB WIG001690 Telomere Extension by Telomerase Telomere Extension by Telomerase (more detail) 19 NA Homo sapiens

Protein Lounge FOX000731 Genes in the cancer module 440 (more detail) 19 NA Homo sapiens

MSigDB WIG000720 Genes involved in Base Excision Repair (more detail) 19 NA Homo sapiens

MSigDB TAX017958 GO:0010528 biological process regulation of transposition Any process that modulates the frequency, rate or extent of transposition. Transposition results in (more detail) 19 NA Homo sapiens

GOA IEI011606 Protein protein interactors of human gene RPS6KA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS6KA4 (SwissProt I (more detail) 19 17535438 Homo sapiens

I2D TAX022749 GO:0035162 biological process embryonic hemopoiesis The stages of blood cell formation that take place within the embryo. (more detail) 19 NA Homo sapiens

GOA IEI011023 Protein protein interactors of human gene RASGRF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RASGRF1 (SwissProt I (more detail) 19 17535438 Homo sapiens

I2D IEI012789 Protein protein interactors of human gene SOX9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOX9 (SwissProt ID=P (more detail) 19 17535438 Homo sapiens

I2D TAX017959 GO:0010529 biological process negative regulation of transposition Any process that decreases the frequency, rate or extent of transposition. Transposition results in (more detail) 19 NA Homo sapiens

GOA IEI011536 Protein protein interactors of human gene RPL37 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL37 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D MOX001383 Genes associated with Computational Drug Signature 4 Aminodiphenylamine Genes associated with Computational Drug Signature 4-Aminodiphenylamine, curated by the Drug Signatu (more detail) 19 25990557 Homo sapiens

DSigDB TAX015969 GO:0005849 cellular component mRNA cleavage factor complex Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules. (more detail) 19 NA Homo sapiens

GOA IEI004387 Protein protein interactors of human gene F12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene F12 (SwissProt ID=P0 (more detail) 19 17535438 Homo sapiens

I2D IEI004569 Protein protein interactors of human gene FANCF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FANCF (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX031519 GO:0102567 molecular function phospholipase A2 activity (consuming 1,2 dipalmitoylphosphatidylcholine) Catalysis of the reaction: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn- (more detail) 19 NA Homo sapiens

GOA WAG001230 Vitamin B6 metabolism (more detail) 19 NA Homo sapiens

KEGG WIG001970 Nucleotide Metabolism Nucleotide Metabolism (more detail) 19 NA Homo sapiens

WikiPathway MOX016127 Genes associated with Computational Drug Signature floxuridine Genes associated with Computational Drug Signature floxuridine, curated by the Drug Signature Databa (more detail) 19 25990557 Homo sapiens

DSigDB WAG000813 Maturity onset diabetes of the young About 2-5% of type II diabetic patients suffer from a monogenic disease with autosomal domint inheri (more detail) 19 NA Homo sapiens

KEGG WAG000640 role of erk5 in neuronal survival pathway Axons extend significant distances to innervate target tissues. At the site of innervation, target (more detail) 19 NA Homo sapiens

BioCarta WIG000929 Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (more detail) 19 NA Homo sapiens

MSigDB MOX015811 Genes associated with Computational Drug Signature Valspodar Genes associated with Computational Drug Signature Valspodar, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB IEI002349 Protein protein interactors of human gene CENPX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CENPX (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI000196 Protein protein interactors of human gene ACTR5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACTR5 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI008468 Protein protein interactors of human gene MYO18A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYO18A (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D TAX031520 GO:0102568 molecular function phospholipase A2 activity consuming 1,2 dioleoylphosphatidylethanolamine) Catalysis of the reaction: 1-18:1-2-18:1-phosphatidylethanolamine + H2O = 1-oleoyl-sn-glycero-3-phos (more detail) 19 NA Homo sapiens

GOA TAX023239 GO:0036065 biological process fucosylation The covalent attachment of a fucosyl group to an acceptor molecule. (more detail) 19 NA Homo sapiens

GOA IEI008279 Protein protein interactors of human gene MSL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MSL1 (SwissProt ID=Q (more detail) 29 17535438 Homo sapiens

I2D TAX024010 GO:0042771 biological process intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic (more detail) 29 NA Homo sapiens

GOA TAX025586 GO:0046471 biological process phosphatidylglycerol metabolic process The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids (more detail) 29 NA Homo sapiens

GOA IEI012673 Protein protein interactors of human gene SNCAIP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNCAIP (SwissProt ID (more detail) 29 17535438 Homo sapiens

I2D IEI012062 Protein protein interactors of human gene SETD1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SETD1A (SwissProt ID (more detail) 29 17535438 Homo sapiens

I2D IEI009032 Protein protein interactors of human gene NR2F2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR2F2 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI013264 Protein protein interactors of human gene SYMPK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SYMPK (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D WIG000340 Control of skeletal myogenesis by HDAC and calcium/calmodulin dependent kinase (CaMK) The differentiation of muscle cells is transcriptionally regulated, in part by the myocyte enhancer (more detail) 29 NA Homo sapiens

MSigDB WAG000218 ceramide signaling pathway Over 1,000 papers and reviews have been written about the role of ceramide in the production of prog (more detail) 29 NA Homo sapiens

BioCarta WAG000635 fc epsilon receptor i signaling in mast cells The Fc Epsilon Receptor 1 sigling pathway in mast cells uses multiple core sigl path to achieve its (more detail) 29 NA Homo sapiens

BioCarta TAX013219 GO:0000027 biological process ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large (more detail) 29 NA Homo sapiens

GOA WIG000630 Thyroid cancer Papillary thyroid carcinoma (PTC), the most frequent neoplasia originating from the thyroid epitheli (more detail) 29 NA Homo sapiens

MSigDB MOX000702 Genes associated with Computational Drug Signature beta Lapachone Genes associated with Computational Drug Signature beta-Lapachone, curated by the Drug Signature Dat (more detail) 29 25990557 Homo sapiens

DSigDB MOX000209 Genes associated with Computational Drug Signature Pararosaniline Genes associated with Computational Drug Signature Pararosaniline, curated by the Drug Signature Dat (more detail) 29 25990557 Homo sapiens

DSigDB MOX007577 Genes associated with Computational Drug Signature CGP 60474 Genes associated with Computational Drug Signature CGP 60474, curated by the Drug Signature Database (more detail) 29 25990557 Homo sapiens

DSigDB IEI012573 Protein protein interactors of human gene SLU7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLU7 (SwissProt ID=O (more detail) 31 17535438 Homo sapiens

I2D IEI003753 Protein protein interactors of human gene DPM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DPM1 (SwissProt ID=O (more detail) 31 17535438 Homo sapiens

I2D IEI006981 Protein protein interactors of human gene KNG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KNG1 (SwissProt ID=P (more detail) 31 17535438 Homo sapiens

I2D IEI010195 Protein protein interactors of human gene POLDIP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLDIP2 (SwissProt I (more detail) 31 17535438 Homo sapiens

I2D IEI003427 Protein protein interactors of human gene DDX46 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX46 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI008536 Protein protein interactors of human gene NABP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NABP2 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI005793 Protein protein interactors of human gene HEMGN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HEMGN (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D TAX020540 GO:0030513 biological process positive regulation of BMP signaling pathway Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activ (more detail) 31 NA Homo sapiens

GOA IEI009545 Protein protein interactors of human gene PBX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PBX2 (SwissProt ID=P (more detail) 31 17535438 Homo sapiens

I2D IEI009994 Protein protein interactors of human gene PKN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PKN2 (SwissProt ID=Q (more detail) 31 17535438 Homo sapiens

I2D IEI004856 Protein protein interactors of human gene FOSL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOSL2 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI013597 Protein protein interactors of human gene TFAM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TFAM (SwissProt ID=Q (more detail) 31 17535438 Homo sapiens

I2D IEI002241 Protein protein interactors of human gene CDK12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK12 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D WAG001047 Signaling mediated by p38 alpha and p38 beta (more detail) 31 NA Homo sapiens

NCI-Nature Curated FEX000317 Breast Wang04 36genes Table 3. Gene expression was analyzed in five pairs of 5-fluorouracil (5-FU) resistant and parental (more detail) 31 15548681 Homo sapiens

GeneSigDB WAG000266 IL1 mediated signaling events (more detail) 31 NA Homo sapiens

NCI-Nature Curated MEX000557 Genes associated with Approved Drug etoposide Genes associated with Approved Drug etoposide, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB TAX001276 Genes annotated by the GO term GO:0016410. Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule. (more detail) 24 NA Homo sapiens

MSigDB MOX003346 Genes associated with Computational Drug Signature Tozasertib Genes associated with Computational Drug Signature Tozasertib, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens

DSigDB MEX000381 Genes associated with Approved Drug liothyronine Genes associated with Approved Drug liothyronine, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB MOX014363 Genes associated with Computational Drug Signature parthenolide Genes associated with Computational Drug Signature parthenolide, curated by the Drug Signature Datab (more detail) 24 25990557 Homo sapiens

DSigDB WIG000453 TPO Signaling Pathway Thrombopoietin (TPO) binds to its receptor inducing aggregation and activation. TPO signals its grow (more detail) 24 NA Homo sapiens

MSigDB IEI014911 Protein protein interactors of human gene VPS33B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VPS33B (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D TAX027305 GO:0051984 biological process positive regulation of chromosome segregation Any process that activates or increases the frequency, rate or extent of chromosome segregation, the (more detail) 24 NA Homo sapiens

GOA IEI012027 Protein protein interactors of human gene SERPINA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERPINA5 (SwissProt (more detail) 24 17535438 Homo sapiens

I2D TAX030812 GO:0097346 cellular component INO80 type complex A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more tha (more detail) 24 NA Homo sapiens

GOA IEI015172 Protein protein interactors of human gene YTHDC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YTHDC2 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D IEI002460 Protein protein interactors of human gene CHD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD1 (SwissProt ID=O (more detail) 24 17535438 Homo sapiens

I2D TAX034913 GO:2000765 biological process regulation of cytoplasmic translation Any process that modulates the frequency, rate or extent of cytoplasmic translation. (more detail) 24 NA Homo sapiens

GOA IEI009549 Protein protein interactors of human gene PC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PC (SwissProt ID=P11 (more detail) 24 17535438 Homo sapiens

I2D IEI007476 Protein protein interactors of human gene LSM6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSM6 (SwissProt ID=P (more detail) 24 17535438 Homo sapiens

I2D IEI003819 Protein protein interactors of human gene DTX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DTX1 (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D IEI009698 Protein protein interactors of human gene PDK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDK1 (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D IEI009602 Protein protein interactors of human gene PCGF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCGF1 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI003443 Protein protein interactors of human gene DEAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DEAF1 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D WIG000872 Genes involved in Gluconeogenesis (more detail) 33 NA Homo sapiens

MSigDB MOX002066 Genes associated with Computational Drug Signature AH 6809 Genes associated with Computational Drug Signature AH 6809, curated by the Drug Signature Database ( (more detail) 33 25990557 Homo sapiens

DSigDB WAG000438 Signaling events mediated by HDAC Class II (more detail) 33 NA Homo sapiens

NCI-Nature Curated MOX003361 Genes associated with Computational Drug Signature N Oleoyldopamine Genes associated with Computational Drug Signature N-Oleoyldopamine, curated by the Drug Signature D (more detail) 33 25990557 Homo sapiens

DSigDB MOX004895 Genes associated with Computational Drug Signature gemfibrozil Genes associated with Computational Drug Signature gemfibrozil, curated by the Drug Signature Databa (more detail) 33 25990557 Homo sapiens

DSigDB TAX000171 Genes annotated by the GO term GO:0042770. A cascade of processes induced by the detection of DNA damage within a cell. (more detail) 33 NA Homo sapiens

MSigDB WAG001060 Role of Calcineurin dependent NFAT signaling in lymphocytes (more detail) 33 NA Homo sapiens

NCI-Nature Curated WIG000073 Signaling events mediated by HDAC Class II (more detail) 33 NA Homo sapiens

MSigDB IEI001553 Protein protein interactors of human gene C1QA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C1QA (SwissProt ID=P (more detail) 33 17535438 Homo sapiens

I2D IEI015230 Protein protein interactors of human gene ZBTB7B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB7B (SwissProt ID (more detail) 33 17535438 Homo sapiens

I2D IEI005641 Protein protein interactors of human gene H1 3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H1-3 (SwissProt ID=P (more detail) 33 17535438 Homo sapiens

I2D IEI000327 Protein protein interactors of human gene ADSS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADSS2 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI013675 Protein protein interactors of human gene THOC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THOC5 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI011071 Protein protein interactors of human gene RBM15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM15 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI010213 Protein protein interactors of human gene POLR1E from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR1E (SwissProt ID (more detail) 33 17535438 Homo sapiens

I2D IEI001831 Protein protein interactors of human gene CAST from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAST (SwissProt ID=P (more detail) 33 17535438 Homo sapiens

I2D IEI009482 Protein protein interactors of human gene PAPOLA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAPOLA (SwissProt ID (more detail) 35 17535438 Homo sapiens

I2D TAX027891 GO:0060412 biological process ventricular septum morphogenesis The developmental process in which a ventricular septum is generated and organized. A ventricular se (more detail) 35 NA Homo sapiens

GOA IEI004817 Protein protein interactors of human gene FLT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FLT1 (SwissProt ID=P (more detail) 35 17535438 Homo sapiens

I2D TAX025523 GO:0046329 biological process negative regulation of JNK cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction me (more detail) 35 NA Homo sapiens

GOA TAX022050 GO:0033238 biological process regulation of cellular amine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by w (more detail) 35 NA Homo sapiens

GOA IEI007263 Protein protein interactors of human gene LIG3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LIG3 (SwissProt ID=P (more detail) 35 17535438 Homo sapiens

I2D TAX025003 GO:0045191 biological process regulation of isotype switching Any process that modulates the frequency, rate or extent of isotype switching. (more detail) 35 NA Homo sapiens

GOA IEI013008 Protein protein interactors of human gene SS18L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SS18L1 (SwissProt ID (more detail) 35 17535438 Homo sapiens

I2D IEI010550 Protein protein interactors of human gene PRPSAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRPSAP1 (SwissProt I (more detail) 35 17535438 Homo sapiens

I2D IEI012813 Protein protein interactors of human gene SPAG9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPAG9 (SwissProt ID= (more detail) 35 17535438 Homo sapiens

I2D TAX022229 GO:0033762 biological process response to glucagon Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 35 NA Homo sapiens

GOA IEI015235 Protein protein interactors of human gene ZBTB9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB9 (SwissProt ID= (more detail) 35 17535438 Homo sapiens

I2D FOX000009 Neighborhood of ANP32B Neighborhood of ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B in the GCM (more detail) 35 NA Homo sapiens

MSigDB WIG000269 BCR Signaling Pathway Significant progress has been made towards delineation of the intrinsic molecular processes that reg (more detail) 35 NA Homo sapiens

MSigDB MOX002771 Genes associated with Computational Drug Signature Romidepsin Genes associated with Computational Drug Signature Romidepsin, curated by the Drug Signature Databas (more detail) 35 25990557 Homo sapiens

DSigDB WAG000437 FOXM1 transcription factor network (more detail) 35 NA Homo sapiens

NCI-Nature Curated IEI010117 Protein protein interactors of human gene PLS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLS3 (SwissProt ID=P (more detail) 37 17535438 Homo sapiens

I2D TAX016968 GO:0007566 biological process embryo implantation Attachment of the blastocyst to the uterine lining. (more detail) 37 NA Homo sapiens

GOA WEX000045 IL 2 Signaling The genes related to il-2 signaling (immune response) in immune using next-generation sequencer (NGS (more detail) 37 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI014214 Protein protein interactors of human gene TRIB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIB3 (SwissProt ID= (more detail) 37 17535438 Homo sapiens

I2D IEI002178 Protein protein interactors of human gene CDC25B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC25B (SwissProt ID (more detail) 37 17535438 Homo sapiens

I2D IEI015087 Protein protein interactors of human gene WT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WT1 (SwissProt ID=P1 (more detail) 37 17535438 Homo sapiens

I2D WAG000445 FOXA2 and FOXA3 transcription factor networks (more detail) 37 NA Homo sapiens

NCI-Nature Curated TAX013337 GO:0000271 biological process polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of man (more detail) 37 NA Homo sapiens

GOA MOX014776 Genes associated with Computational Drug Signature Redoxal Genes associated with Computational Drug Signature Redoxal, curated by the Drug Signature Database ( (more detail) 37 25990557 Homo sapiens

DSigDB FEX011547 hsa miR 628 5p HITS-CLIP, Functional MTI (Weak) (more detail) 37 NA Homo sapiens

mirTARbase IEI001733 Protein protein interactors of human gene CALD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CALD1 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D TAX032346 GO:1902036 biological process regulation of hematopoietic stem cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation. (more detail) 26 NA Homo sapiens

GOA IEI005575 Protein protein interactors of human gene GTF2A1L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2A1L (SwissProt I (more detail) 26 17535438 Homo sapiens

I2D IEI011671 Protein protein interactors of human gene RTCA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RTCA (SwissProt ID=O (more detail) 26 17535438 Homo sapiens

I2D IEI010339 Protein protein interactors of human gene PPP1R10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R10 (SwissProt I (more detail) 26 17535438 Homo sapiens

I2D TAX027765 GO:0060251 biological process regulation of glial cell proliferation Any process that modulates the frequency, rate or extent of glial cell proliferation. (more detail) 26 NA Homo sapiens

GOA TAX020785 GO:0031063 biological process regulation of histone deacetylation Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histon (more detail) 26 NA Homo sapiens

GOA TAX021962 GO:0033077 biological process T cell differentiation in thymus The process in which a precursor cell type acquires the specialized features of a T cell via a diffe (more detail) 26 NA Homo sapiens

GOA TAX029006 GO:0070566 molecular function adenylyltransferase activity Catalysis of the transfer of an adenylyl group to an acceptor. (more detail) 26 NA Homo sapiens

GOA TAX029494 GO:0071480 biological process cellular response to gamma radiation Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 26 NA Homo sapiens

GOA IEI004631 Protein protein interactors of human gene FBXO11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO11 (SwissProt ID (more detail) 26 17535438 Homo sapiens

I2D IEI006974 Protein protein interactors of human gene KMT2C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KMT2C (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI015373 Protein protein interactors of human gene ZMYND8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZMYND8 (SwissProt ID (more detail) 26 17535438 Homo sapiens

I2D TAX016558 GO:0006730 biological process one carbon metabolic process The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation (more detail) 26 NA Homo sapiens

GOA IEI010630 Protein protein interactors of human gene PSMB10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMB10 (SwissProt ID (more detail) 26 17535438 Homo sapiens

I2D IEI000785 Protein protein interactors of human gene ARF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARF4 (SwissProt ID=P (more detail) 26 17535438 Homo sapiens

I2D IEI012745 Protein protein interactors of human gene SOCS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOCS2 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI001851 Protein protein interactors of human gene CBFA2T3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CBFA2T3 (SwissProt I (more detail) 26 17535438 Homo sapiens

I2D WEX000067 Myc The genes related to myc (signaling pathways) in tumor using next-generation sequencer (NGS) readout (more detail) 26 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas TAX014869 GO:0003950 molecular function NAD+ ADP ribosyltransferase activity Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)- (more detail) 26 NA Homo sapiens

GOA IEI001349 Protein protein interactors of human gene BIRC7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BIRC7 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D WAG000821 Urea cycle and metabolism of amino groups (more detail) 26 NA Homo sapiens

KEGG MOX012622 Genes associated with Computational Drug Signature etoposide Genes associated with Computational Drug Signature etoposide, curated by the Drug Signature Database (more detail) 26 25990557 Homo sapiens

DSigDB TAX000425 Genes annotated by the GO term GO:0044271. The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. (more detail) 26 NA Homo sapiens

MSigDB MOX013092 Genes associated with Computational Drug Signature IDARUBICIN Genes associated with Computational Drug Signature IDARUBICIN, curated by the Drug Signature Databas (more detail) 26 25990557 Homo sapiens

DSigDB FEX001472 Leukemia Tissing07 57genes Table 1 Prednisolone-induced changes in gene expression in pediatric ALL (more detail) 26 17218380 Homo sapiens

GeneSigDB MAX000013 Genes up regulated in immunoglobulin light chain amyloidosis plasma cells (ALPC) compared to multiple myeloma (MM) cells. Immunoglobulin light chain amyloidosis (AL) is characterized by a clonal expansion of plasma cells w (more detail) 26 NA Homo sapiens

MSigDB WIG001094 Genes involved in Post translational modification: synthesis of GPI anchored proteins (more detail) 26 NA Homo sapiens

MSigDB MAX000648 The lung adenocarcinoma TSP (tumor sequencing project) genes that were found significantly mutated by at least one method. Determining the genetic basis of cancer requires comprehensive analyses of large collections of hist (more detail) 26 NA Homo sapiens

MSigDB WIG000460 WNT Signaling Pathway Wnt family members are secreted glycoproteins who bind to cell surface receptors such as Frizzled. W (more detail) 26 NA Homo sapiens

MSigDB MEX003752 Genes associated with Perturbagen Signature nystatin Genes associated with Perturbagen Signature nystatin, curated by the Drug Signature Database (DSigDB (more detail) 26 25990557 Homo sapiens

DSigDB MOX002791 Genes associated with Computational Drug Signature Anacardic acid C15:3 Genes associated with Computational Drug Signature Anacardic acid C15:3, curated by the Drug Signatu (more detail) 26 25990557 Homo sapiens

DSigDB IEI014754 Protein protein interactors of human gene USP13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP13 (SwissProt ID= (more detail) 39 17535438 Homo sapiens

I2D IEI001863 Protein protein interactors of human gene CBR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CBR1 (SwissProt ID=P (more detail) 39 17535438 Homo sapiens

I2D IEI007217 Protein protein interactors of human gene LEO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LEO1 (SwissProt ID=Q (more detail) 39 17535438 Homo sapiens

I2D IEI000733 Protein protein interactors of human gene APOB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APOB (SwissProt ID=P (more detail) 39 17535438 Homo sapiens

I2D IEI013621 Protein protein interactors of human gene TFPT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TFPT (SwissProt ID=P (more detail) 39 17535438 Homo sapiens

I2D MOX003141 Genes associated with Computational Drug Signature Calycosin Genes associated with Computational Drug Signature Calycosin, curated by the Drug Signature Database (more detail) 39 25990557 Homo sapiens

DSigDB TAX013786 GO:0001709 biological process cell fate determination A process involved in cell fate commitment. Once determination has taken place, a cell becomes commi (more detail) 39 NA Homo sapiens

GOA FEX000292 Breast Cicatiello04 51genes ER Table 6 List of genes regulated by estrogen in ZR-75.1 cells which are characterized by periodic exp (more detail) 39 15171711 Homo sapiens

GeneSigDB WIG001748 Mitotic Roles of Polo Like Kinase Mitotic Roles of Polo-Like Kinase (more detail) 39 NA Homo sapiens

Protein Lounge TAX026839 GO:0051156 biological process glucose 6 phosphate metabolic process The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative o (more detail) 21 NA Homo sapiens

GOA IEI001001 Protein protein interactors of human gene ASXL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASXL1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI015580 Protein protein interactors of human gene ZNF496 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF496 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D TAX020546 GO:0030520 biological process intracellular estrogen receptor signaling pathway Any series of molecular signals generated as a consequence of an intracellular estrogen receptor bin (more detail) 21 NA Homo sapiens

GOA IEI010215 Protein protein interactors of human gene POLR1G from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR1G (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI002540 Protein protein interactors of human gene CHTF18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHTF18 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI012608 Protein protein interactors of human gene SMCHD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMCHD1 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI010530 Protein protein interactors of human gene PROX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PROX1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI009046 Protein protein interactors of human gene NRBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NRBP1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI010789 Protein protein interactors of human gene PWP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PWP2 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D TAX028106 GO:0060740 biological process prostate gland epithelium morphogenesis The process in which the anatomical structures of epithelia of the prostate gland are generated and (more detail) 21 NA Homo sapiens

GOA TAX034867 GO:2000678 biological process negative regulation of transcription regulatory region DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulator (more detail) 21 NA Homo sapiens

GOA IEI008860 Protein protein interactors of human gene NKX2 1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NKX2-1 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI012874 Protein protein interactors of human gene SPIB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPIB (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI001276 Protein protein interactors of human gene BCL11B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCL11B (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI010199 Protein protein interactors of human gene POLE3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLE3 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI011386 Protein protein interactors of human gene RNF125 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF125 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI005148 Protein protein interactors of human gene GEMIN6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GEMIN6 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI014575 Protein protein interactors of human gene UBE2G1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2G1 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI000139 Protein protein interactors of human gene ACO2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACO2 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D MOX004174 Genes associated with Computational Drug Signature harmaline Genes associated with Computational Drug Signature harmaline, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens

DSigDB FOX000037 Neighborhood of FANCL Neighborhood of FANCL Fanconi anemia, complementation group L in the GCM expression compendium (more detail) 21 NA Homo sapiens

MSigDB FOX000805 Genes in the cancer module 562 (more detail) 21 NA Homo sapiens

MSigDB FEX000729 Breast Lin09 24genes Additional File 1-5. A list of genes corresponding to certain breast cancer related pathways;Cell Cy (more detail) 21 19695104 Homo sapiens

GeneSigDB MOX012690 Genes associated with Computational Drug Signature Fisetin Genes associated with Computational Drug Signature Fisetin, curated by the Drug Signature Database ( (more detail) 21 25990557 Homo sapiens

DSigDB MOX000811 Genes associated with Computational Drug Signature Delphinidin Genes associated with Computational Drug Signature Delphinidin, curated by the Drug Signature Databa (more detail) 21 25990557 Homo sapiens

DSigDB MOX013466 Genes associated with Computational Drug Signature liothyronine Genes associated with Computational Drug Signature liothyronine, curated by the Drug Signature Datab (more detail) 21 25990557 Homo sapiens

DSigDB WIG001431 CD27 Pathway CD27 Pathway (more detail) 21 NA Homo sapiens

Protein Lounge WAG000045 Signaling events mediated by HDAC Class III (more detail) 21 NA Homo sapiens

NCI-Nature Curated WIG000701 Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B (more detail) 21 NA Homo sapiens

MSigDB MOX000619 Genes associated with Computational Drug Signature Dihydrocapsaicin Genes associated with Computational Drug Signature Dihydrocapsaicin, curated by the Drug Signature D (more detail) 21 25990557 Homo sapiens

DSigDB MAX001711 Genes up regulated in SW480 cells (colon cancer with mutated p53 [GeneID=7157]) upon expression of BRCA1 [GeneID=672] off an adenovirus vector. The breast and ovarian cancer susceptibility gene product BRCA1 has been reported to be expressed in (more detail) 21 NA Homo sapiens

MSigDB IEI004041 Protein protein interactors of human gene EIF3CL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF3CL (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D TAX026775 GO:0051059 molecular function NF kappaB binding Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA (more detail) 28 NA Homo sapiens

GOA TAX024707 GO:0044344 biological process cellular response to fibroblast growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 28 NA Homo sapiens

GOA IEI012820 Protein protein interactors of human gene SPARC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPARC (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI003890 Protein protein interactors of human gene E2F2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene E2F2 (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI001206 Protein protein interactors of human gene BACE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BACE1 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI001419 Protein protein interactors of human gene BRAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRAP (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI007106 Protein protein interactors of human gene L3MBTL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene L3MBTL1 (SwissProt I (more detail) 28 17535438 Homo sapiens

I2D TAX035023 GO:2001038 biological process regulation of cellular response to drug Any process that modulates the frequency, rate or extent of cellular response to drug. (more detail) 28 NA Homo sapiens

GOA IEI010826 Protein protein interactors of human gene QRICH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene QRICH1 (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D IEI011907 Protein protein interactors of human gene SDF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SDF4 (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI012956 Protein protein interactors of human gene SRCAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRCAP (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI014137 Protein protein interactors of human gene TPP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TPP1 (SwissProt ID=O (more detail) 28 17535438 Homo sapiens

I2D WIG000728 Genes involved in Biosynthesis of the N glycan precursor (dolichol lipid linked oligosaccharide, LLO) and transfer to a nascent protein (more detail) 28 NA Homo sapiens

MSigDB TAX000476 Genes annotated by the GO term GO:0051099. Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. (more detail) 28 NA Homo sapiens

MSigDB MOX000840 Genes associated with Computational Drug Signature 15442 64 5 Genes associated with Computational Drug Signature 15442-64-5, curated by the Drug Signature Databas (more detail) 28 25990557 Homo sapiens

DSigDB WAG001055 FoxO family signaling (more detail) 28 NA Homo sapiens

NCI-Nature Curated WIG000734 Genes involved in Ca dependent events (more detail) 28 NA Homo sapiens

MSigDB WIG000880 Genes involved in Glycolysis (more detail) 28 NA Homo sapiens

MSigDB WIG000177 Calcium signaling in the CD4+ TCR pathway (more detail) 28 NA Homo sapiens

MSigDB MOX017593 Genes associated with Computational Drug Signature uracil Genes associated with Computational Drug Signature uracil, curated by the Drug Signature Database (D (more detail) 28 25990557 Homo sapiens

DSigDB TAX000571 Genes annotated by the GO term GO:0030166. The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. (more detail) 15 NA Homo sapiens

MSigDB TAX016220 GO:0006271 biological process DNA strand elongation involved in DNA replication The process in which a DNA strand is synthesized from template DNA during replication by the action (more detail) 15 NA Homo sapiens

GOA TAX017650 GO:0009303 biological process rRNA transcription The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DN (more detail) 15 NA Homo sapiens

GOA TAX024554 GO:0043982 biological process histone H4 K8 acetylation The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 (more detail) 15 NA Homo sapiens

GOA TAX020095 GO:0021879 biological process forebrain neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron that (more detail) 15 NA Homo sapiens

GOA IEI003380 Protein protein interactors of human gene DCUN1D5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCUN1D5 (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D IEI005889 Protein protein interactors of human gene HLF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HLF (SwissProt ID=Q1 (more detail) 15 17535438 Homo sapiens

I2D TAX031691 GO:0140053 biological process mitochondrial gene expression The process in which a mitochondrial gene's sequence is converted into a mature gene product or prod (more detail) 15 NA Homo sapiens

GOA TAX022014 GO:0033169 biological process histone H3 K9 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the his (more detail) 15 NA Homo sapiens

GOA TAX017527 GO:0009129 biological process pyrimidine nucleoside monophosphate metabolic process The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consis (more detail) 15 NA Homo sapiens

GOA TAX019514 GO:0018298 biological process protein chromophore linkage The covalent or noncovalent attachment of a chromophore to a protein. (more detail) 15 NA Homo sapiens

GOA TAX015201 GO:0004523 molecular function RNA DNA hybrid ribonuclease activity Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters. (more detail) 15 NA Homo sapiens

GOA IEI008942 Protein protein interactors of human gene NOP10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOP10 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI002573 Protein protein interactors of human gene CITED2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CITED2 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI010237 Protein protein interactors of human gene POLR3G from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR3G (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI005652 Protein protein interactors of human gene H2AC21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AC21 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D TAX013437 GO:0000478 biological process endonucleolytic cleavage involved in rRNA processing Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript (more detail) 15 NA Homo sapiens

GOA WIG001496 Fanconi's Anaemia Pathway Fanconi's Anaemia Pathway (more detail) 15 NA Homo sapiens

Protein Lounge WIG000036 Circadian rhythm pathway (more detail) 15 NA Homo sapiens

MSigDB WIG000688 Genes involved in Amine derived hormones (more detail) 15 NA Homo sapiens

MSigDB WIG001106 Genes involved in Processive synthesis on the lagging strand (more detail) 15 NA Homo sapiens

MSigDB TAX000742 Genes annotated by the GO term GO:0006364. Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. (more detail) 15 NA Homo sapiens

MSigDB MEX001079 Genes associated with Approved Drug vargatef Genes associated with Approved Drug vargatef, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB MEX002345 Genes associated with Kinase Inhibitor bisindolylmaleimide i Genes associated with Kinase Inhibitor bisindolylmaleimide i, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MEX001495 Genes associated with Kinase Inhibitor H 89 DIHYDROCHLORIDE Genes associated with Kinase Inhibitor H-89 DIHYDROCHLORIDE, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB TAX022409 GO:0034312 biological process diol biosynthetic process The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two (more detail) 15 NA Homo sapiens

GOA TAX022432 GO:0034356 biological process NAD biosynthesis via nicotinamide riboside salvage pathway The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (more detail) 15 NA Homo sapiens

GOA TAX016356 GO:0006474 biological process N terminal protein amino acid acetylation The acetylation of the N-terminal amino acid of proteins. (more detail) 15 NA Homo sapiens

GOA TAX016452 GO:0006586 biological process indolalkylamine metabolic process The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives contain (more detail) 15 NA Homo sapiens

GOA TAX017150 GO:0008242 molecular function omega peptidase activity Catalysis of the removal of terminal peptide residues that are substituted, cyclized or linked by is (more detail) 15 NA Homo sapiens

GOA TAX020381 GO:0030214 biological process hyaluronan catabolic process The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurrin (more detail) 15 NA Homo sapiens

GOA MOX014298 Genes associated with Computational Drug Signature oxindole i Genes associated with Computational Drug Signature oxindole i, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens

DSigDB TAX023816 GO:0042403 biological process thyroid hormone metabolic process The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, la (more detail) 15 NA Homo sapiens

GOA TAX001063 Genes annotated by the GO term GO:0008375. Catalysis of the transfer of an N acetylglucosaminyl residue from UDP N acetyl glucosamine to an oligosaccharide. (more detail) 15 NA Homo sapiens

MSigDB TAX000239 Genes annotated by the GO term GO:0006664. The chemical reactions and pathways involving glycolipids, compounds containing (usually) 1 4 linked monosaccharide residues joined by a glycosyl linkage to a lipid. (more detail) 15 NA Homo sapiens

MSigDB TAX015790 GO:0005527 molecular function macrolide binding Interacting selectively and non-covalently with a macrolide, any of a large group of structurally re (more detail) 15 NA Homo sapiens

GOA TAX015791 GO:0005528 molecular function FK506 binding Interacting selectively and non-covalently with the 23-membered macrolide lactone FK506. (more detail) 15 NA Homo sapiens

GOA TAX015854 GO:0005662 cellular component DNA replication factor A complex A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required (more detail) 15 NA Homo sapiens

GOA IEI001758 Protein protein interactors of human gene CAMP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAMP (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D IEI006431 Protein protein interactors of human gene INTS13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS13 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D WIG002006 Biogenic Amine Synthesis Biogenic Amine Synthesis (more detail) 15 NA Homo sapiens

WikiPathway MEX001973 Genes associated with Kinase Inhibitor GSK429286A Genes associated with Kinase Inhibitor GSK429286A, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB MEX002132 Genes associated with Kinase Inhibitor CGP 60474 Genes associated with Kinase Inhibitor CGP 60474, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB MEX002164 Genes associated with Kinase Inhibitor GSK1220512A Genes associated with Kinase Inhibitor GSK1220512A, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB TAX013599 GO:0001056 molecular function RNA polymerase III activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA (more detail) 15 NA Homo sapiens

GOA TAX020991 GO:0031434 molecular function mitogen activated protein kinase kinase binding Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any prote (more detail) 15 NA Homo sapiens

GOA TAX025836 GO:0046965 molecular function retinoid X receptor binding Interacting selectively and non-covalently with a retinoid X receptor. (more detail) 15 NA Homo sapiens

GOA PEX001185 Proteasome: Proteasome subunit The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essenti (more detail) 15 NA Homo sapiens

Pfam IEI011439 Protein protein interactors of human gene RNF38 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF38 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D WAG000664 Regulation of p38 alpha and p38 beta (more detail) 15 NA Homo sapiens

NCI-Nature Curated WAG000533 Repair synthesis for gap filling by DNA polymerase in TC NER (more detail) 15 NA Homo sapiens

Reactome WIG000420 Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells RXR and RAR are nuclear receptors that bind either all trans retinoic (tRA) or 9cis retinoic acid (9 (more detail) 15 NA Homo sapiens

MSigDB MAX000512 Proteins that regulate activity of PRKDC [GeneID=5591]. Double-strand breaks (DSBs) arise endogenously during normal cellular processes and exogenously by g (more detail) 15 NA Homo sapiens

MSigDB WIG001192 Genes involved in SHC mediated signalling (more detail) 15 NA Homo sapiens

MSigDB WIG001420 Methotrexate Pathway (Cancer Cell), Pharmacodynamics Methotrexate cellular disposition and effects. (more detail) 15 NA Homo sapiens

PharmGKB WIG001756 Murine METS Protein Signaling Murine METS Protein Signaling (more detail) 15 NA Homo sapiens

Protein Lounge WAG000396 Alkaloid biosynthesis I (more detail) 15 NA Homo sapiens

KEGG MAX000761 Genes in the gray cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. Breast cancer is a heterogeneous disease made of various molecular subtypes with different prognosis (more detail) 15 NA Homo sapiens

MSigDB MEX001548 Genes associated with Kinase Inhibitor su6656 Genes associated with Kinase Inhibitor su6656, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB MEX002180 Genes associated with Kinase Inhibitor Alsterpaullone, 2 Cyanoethyl Genes associated with Kinase Inhibitor Alsterpaullone, 2-Cyanoethyl, curated by the Drug Signature D (more detail) 15 25990557 Homo sapiens

DSigDB TAX016572 GO:0006750 biological process glutathione biosynthetic process The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutam (more detail) 15 NA Homo sapiens

GOA TAX018797 GO:0015936 biological process coenzyme A metabolic process The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')panta (more detail) 15 NA Homo sapiens

GOA TAX033418 GO:1904380 biological process endoplasmic reticulum mannose trimming Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control (more detail) 15 NA Homo sapiens

GOA TAX015214 GO:0004549 molecular function tRNA specific ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules. (more detail) 15 NA Homo sapiens

GOA IEI002667 Protein protein interactors of human gene CLP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLP1 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D WAG000667 APC/C mediated degradation of cell cycle proteins (more detail) 15 NA Homo sapiens

Reactome MEX001388 Genes associated with Kinase Inhibitor Kinome 406 Genes associated with Kinase Inhibitor Kinome_406, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB MEX002159 Genes associated with Kinase Inhibitor Kinome 6 Genes associated with Kinase Inhibitor Kinome_6, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB TAX024494 GO:0043650 biological process dicarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic ac (more detail) 15 NA Homo sapiens

GOA WIG001189 Genes involved in SHC1 events in EGFR signaling (more detail) 15 NA Homo sapiens

MSigDB MEX001966 Genes associated with Kinase Inhibitor CHEMBL1950303 Genes associated with Kinase Inhibitor CHEMBL1950303, curated by the Drug Signature Database (DSigDB (more detail) 15 25990557 Homo sapiens

DSigDB TAX021445 GO:0032300 cellular component mismatch repair complex Any complex formed of proteins that act in mismatch repair. (more detail) 15 NA Homo sapiens

GOA TAX023659 GO:0042089 biological process cytokine biosynthetic process The chemical reactions and pathways resulting in the formation of cytokines, any of a group of prote (more detail) 15 NA Homo sapiens

GOA TAX022522 GO:0034483 molecular function heparan sulfate sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5' (more detail) 15 NA Homo sapiens

GOA TAX029270 GO:0071044 biological process histone mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA). (more detail) 15 NA Homo sapiens

GOA TAX029099 GO:0070742 molecular function C2H2 zinc finger domain binding Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H (more detail) 15 NA Homo sapiens

GOA IEI002058 Protein protein interactors of human gene CCNT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNT2 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI004404 Protein protein interactors of human gene FAAP20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAAP20 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI004649 Protein protein interactors of human gene FBXO4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO4 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D WAG001552 Repair synthesis of patch ~27 30 bases long by DNA polymerase (more detail) 15 NA Homo sapiens

Reactome WIG000355 IL 3 signaling pathway Interleukin-3 promotes the proliferation and differentiation of hematopoietic cells through binding (more detail) 15 NA Homo sapiens

MSigDB MOX000439 Genes associated with Computational Drug Signature Surfactin Genes associated with Computational Drug Signature Surfactin, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB TAX021299 GO:0032039 cellular component integrator complex A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-en (more detail) 15 NA Homo sapiens

GOA TAX017601 GO:0009209 biological process pyrimidine ribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosp (more detail) 15 NA Homo sapiens

GOA TAX013560 GO:0000963 biological process mitochondrial RNA processing The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more ma (more detail) 15 NA Homo sapiens

GOA TAX024553 GO:0043981 biological process histone H4 K5 acetylation The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 (more detail) 15 NA Homo sapiens

GOA TAX015334 GO:0004708 molecular function MAP kinase kinase activity Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu (more detail) 15 NA Homo sapiens

GOA IEI003156 Protein protein interactors of human gene CUEDC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUEDC2 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI004089 Protein protein interactors of human gene ELK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELK3 (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D TAX017189 GO:0008301 molecular function DNA binding, bending The activity of binding selectively and non-covalently to and distorting the original structure of D (more detail) 18 NA Homo sapiens

GOA IEI014097 Protein protein interactors of human gene TOR1AIP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TOR1AIP2 (SwissProt (more detail) 18 17535438 Homo sapiens

I2D TAX029187 GO:0070920 biological process regulation of production of small RNA involved in gene silencing by RNA Any process that modulates the frequency, rate or extent of the production of small RNA involved in (more detail) 18 NA Homo sapiens

GOA IEI008794 Protein protein interactors of human gene NFIX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFIX (SwissProt ID=Q (more detail) 18 17535438 Homo sapiens

I2D IEI003849 Protein protein interactors of human gene DUSP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP3 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI008076 Protein protein interactors of human gene MMS22L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MMS22L (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI006284 Protein protein interactors of human gene IKZF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IKZF2 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI008946 Protein protein interactors of human gene NOP53 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOP53 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI004092 Protein protein interactors of human gene ELL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELL2 (SwissProt ID=O (more detail) 18 17535438 Homo sapiens

I2D TAX016856 GO:0007221 biological process positive regulation of transcription of Notch receptor target The activation of transcription of specific genes as a result of Notch signaling, mediated by the No (more detail) 18 NA Homo sapiens

GOA IEI011822 Protein protein interactors of human gene SCAF11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCAF11 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D TAX031916 GO:1900363 biological process regulation of mRNA polyadenylation Any process that modulates the frequency, rate or extent of mRNA polyadenylation. (more detail) 18 NA Homo sapiens

GOA TAX029696 GO:0071837 molecular function HMG box domain binding Interacting selectively and non-covalently with an HMG box domain, a protein domain that consists of (more detail) 18 NA Homo sapiens

GOA TAX018886 GO:0016137 biological process glycoside metabolic process The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is sub (more detail) 18 NA Homo sapiens

GOA IEI014814 Protein protein interactors of human gene UTP18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UTP18 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI006948 Protein protein interactors of human gene KLHL9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHL9 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D TAX032696 GO:1902914 biological process regulation of protein polyubiquitination Any process that modulates the frequency, rate or extent of protein polyubiquitination. (more detail) 18 NA Homo sapiens

GOA IEI005988 Protein protein interactors of human gene HOXC9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXC9 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI003976 Protein protein interactors of human gene EFHD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFHD2 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI014235 Protein protein interactors of human gene TRIM31 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM31 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI006592 Protein protein interactors of human gene JARID2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JARID2 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D MEX000105 Genes associated with Approved Drug valproic acid Genes associated with Approved Drug valproic acid, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB MEX001105 Genes associated with Approved Drug regorafenib Genes associated with Approved Drug regorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB MEX000360 Genes associated with Approved Drug floxuridine Genes associated with Approved Drug floxuridine, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB TAX000539 Genes annotated by the GO term GO:0006493. The formation of O glycans by addition of glycosyl groups either to the hydroxyl group of peptidyl serine, peptidyl threonine, peptidyl hydroxylysine, or peptidyl hydroxyproline, or to the phenol group of peptidyl tyrosine. (more detail) 18 NA Homo sapiens

MSigDB WAG001451 hypoxia and p53 in the cardiovascular system Hypoxic stress, like D damage, induces p53 protein accumulation and p53-dependent apoptosis in oncog (more detail) 18 NA Homo sapiens

BioCarta MOX015872 Genes associated with Computational Drug Signature Vorinostat Genes associated with Computational Drug Signature Vorinostat, curated by the Drug Signature Databas (more detail) 18 25990557 Homo sapiens

DSigDB WIG001243 Genes involved in Synthesis and interconversion of nucleotide di and triphosphates (more detail) 18 NA Homo sapiens

MSigDB TAX016132 GO:0006103 biological process 2 oxoglutarate metabolic process The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is (more detail) 18 NA Homo sapiens

GOA MOX004092 Genes associated with Computational Drug Signature fenthion Genes associated with Computational Drug Signature fenthion, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB MOX003401 Genes associated with Computational Drug Signature Nilotinib Genes associated with Computational Drug Signature Nilotinib, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB WIG000387 Nerve growth factor pathway (NGF) Nerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and prolifera (more detail) 18 NA Homo sapiens

MSigDB MEX000414 Genes associated with Approved Drug cytarabine Genes associated with Approved Drug cytarabine, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB TAX001104 Genes annotated by the GO term GO:0016830. Catalysis of the cleavage of C C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. (more detail) 18 NA Homo sapiens

MSigDB TAX001022 Genes annotated by the GO term GO:0005657. The Y shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. (more detail) 18 NA Homo sapiens

MSigDB WIG001074 Genes involved in Phosphorylation of the APC/C (more detail) 18 NA Homo sapiens

MSigDB TAX000774 Genes annotated by the GO term GO:0044272. The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. (more detail) 18 NA Homo sapiens

MSigDB TAX000731 Genes annotated by the GO term GO:0042254. The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis. (more detail) 18 NA Homo sapiens

MSigDB TAX000330 Genes annotated by the GO term GO:0007127. Progression through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells. (more detail) 18 NA Homo sapiens

MSigDB WAG000230 egf signaling pathway The epidermal growth factor (EGF) peptide induces cellular proliferation through the EGF receptor, w (more detail) 18 NA Homo sapiens

BioCarta TAX025196 GO:0045648 biological process positive regulation of erythrocyte differentiation Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation (more detail) 30 NA Homo sapiens

GOA TAX018001 GO:0010613 biological process positive regulation of cardiac muscle hypertrophy Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or (more detail) 30 NA Homo sapiens

GOA IEI005208 Protein protein interactors of human gene GINS4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GINS4 (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D IEI010196 Protein protein interactors of human gene POLDIP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLDIP3 (SwissProt I (more detail) 30 17535438 Homo sapiens

I2D TAX029174 GO:0070897 biological process DNA templated transcriptional preinitiation complex assembly The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcript (more detail) 30 NA Homo sapiens

GOA IEI006747 Protein protein interactors of human gene KCTD5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KCTD5 (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D IEI012025 Protein protein interactors of human gene SERPINA3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERPINA3 (SwissProt (more detail) 30 17535438 Homo sapiens

I2D IEI010808 Protein protein interactors of human gene PYGB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PYGB (SwissProt ID=P (more detail) 30 17535438 Homo sapiens

I2D TAX018361 GO:0014742 biological process positive regulation of muscle hypertrophy Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. (more detail) 30 NA Homo sapiens

GOA TAX020708 GO:0030901 biological process midbrain development The process whose specific outcome is the progression of the midbrain over time, from its formation (more detail) 30 NA Homo sapiens

GOA TAX032402 GO:1902175 biological process regulation of oxidative stress induced intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic ap (more detail) 30 NA Homo sapiens

GOA IEI011988 Protein protein interactors of human gene SENP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SENP1 (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D IEI011562 Protein protein interactors of human gene RPP30 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPP30 (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D IEI003033 Protein protein interactors of human gene CS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CS (SwissProt ID=O75 (more detail) 30 17535438 Homo sapiens

I2D TAX000237 Genes annotated by the GO term GO:0046474. The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O acyl, O alkyl, or O alkenyl group attached to the glycerol residue. (more detail) 30 NA Homo sapiens

MSigDB MOX004608 Genes associated with Computational Drug Signature pyrogallol Genes associated with Computational Drug Signature pyrogallol, curated by the Drug Signature Databas (more detail) 30 25990557 Homo sapiens

DSigDB FEX012194 hsa miR 6800 5p HITS-CLIP, Functional MTI (Weak) (more detail) 30 NA Homo sapiens

mirTARbase TAX001425 Genes annotated by the GO term GO:0016765. Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor). (more detail) 30 NA Homo sapiens

MSigDB MAX003341 Top genes up regulated in MM4 vs MM1 subgroup of multiple myeloma samples. Bone marrow plasma cells (PCs) from 74 patients with newly diagnosed multiple myeloma (MM), 5 with m (more detail) 30 NA Homo sapiens

MSigDB WIG000093 IL2 signaling events mediated by STAT5 (more detail) 30 NA Homo sapiens

MSigDB MOX016813 Genes associated with Computational Drug Signature etoposide Genes associated with Computational Drug Signature etoposide, curated by the Drug Signature Database (more detail) 30 25990557 Homo sapiens

DSigDB MOX004337 Genes associated with Computational Drug Signature methoxsalen Genes associated with Computational Drug Signature methoxsalen, curated by the Drug Signature Databa (more detail) 30 25990557 Homo sapiens

DSigDB WIG001707 APRIL Pathway APRIL Pathway (more detail) 30 NA Homo sapiens

Protein Lounge MOX005001 Genes associated with Computational Drug Signature CYPROTERONE ACETATE Genes associated with Computational Drug Signature CYPROTERONE ACETATE, curated by the Drug Signatur (more detail) 30 25990557 Homo sapiens

DSigDB IEI012086 Protein protein interactors of human gene SF3B5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SF3B5 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D TAX028918 GO:0070412 molecular function R SMAD binding Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein. (more detail) 23 NA Homo sapiens

GOA IEI015466 Protein protein interactors of human gene ZNF281 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF281 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D TAX031999 GO:1901071 biological process glucosamine containing compound metabolic process The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines). (more detail) 23 NA Homo sapiens

GOA TAX032684 GO:1902895 biological process positive regulation of pri miRNA transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription med (more detail) 23 NA Homo sapiens

GOA IEI013474 Protein protein interactors of human gene TCEAL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCEAL1 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI000861 Protein protein interactors of human gene ARID3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARID3A (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI012941 Protein protein interactors of human gene SPTLC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPTLC1 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI003170 Protein protein interactors of human gene CWC15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CWC15 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI015421 Protein protein interactors of human gene ZNF212 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF212 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI007368 Protein protein interactors of human gene LPCAT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LPCAT1 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI013340 Protein protein interactors of human gene TAF13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF13 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI012659 Protein protein interactors of human gene SNAI2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNAI2 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI002242 Protein protein interactors of human gene CDK13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK13 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D TAX017101 GO:0008171 molecular function O methyltransferase activity Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule. (more detail) 23 NA Homo sapiens

GOA TAX028216 GO:0060969 biological process negative regulation of gene silencing Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or (more detail) 23 NA Homo sapiens

GOA IEI007496 Protein protein interactors of human gene LTF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LTF (SwissProt ID=P0 (more detail) 23 17535438 Homo sapiens

I2D TAX028336 GO:0061157 biological process mRNA destabilization Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradati (more detail) 23 NA Homo sapiens

GOA TAX016962 GO:0007530 biological process sex determination Any process that establishes and transmits the specification of sexual status of an individual organ (more detail) 23 NA Homo sapiens

GOA TAX029848 GO:0072132 biological process mesenchyme morphogenesis The process in which the anatomical structures of a mesenchymal tissue are generated and organized. (more detail) 23 NA Homo sapiens

GOA TAX017120 GO:0008198 molecular function ferrous iron binding Interacting selectively and non-covalently with ferrous iron, Fe(II). (more detail) 23 NA Homo sapiens

GOA MOX004973 Genes associated with Computational Drug Signature Acitretin Genes associated with Computational Drug Signature Acitretin, curated by the Drug Signature Database (more detail) 23 25990557 Homo sapiens

DSigDB WIG001262 Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex (more detail) 23 NA Homo sapiens

MSigDB FEX001704 Liver Chiba04 24genes Table 3. Genes downregulated (ratio (more detail) 23 15452378 Homo sapiens

GeneSigDB TAX000027 Genes annotated by the GO term GO:0006575. The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. (more detail) 23 NA Homo sapiens

MSigDB TAX000169 Genes annotated by the GO term GO:0006308. The chemical reactions and pathways resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3' phosphate group of each constituent deoxyribonucleotide being joined in 3',5' phosphodiester linkage to the 5' hydroxyl group of the deoxyribose moiety of the next one. (more detail) 23 NA Homo sapiens

MSigDB MOX001350 Genes associated with Computational Drug Signature IN1541 Genes associated with Computational Drug Signature IN1541, curated by the Drug Signature Database (D (more detail) 23 25990557 Homo sapiens

DSigDB MOX014717 Genes associated with Computational Drug Signature quinacrine Genes associated with Computational Drug Signature quinacrine, curated by the Drug Signature Databas (more detail) 23 25990557 Homo sapiens

DSigDB FEX003090 StemCell Lim08 23genes Table 5 Genes associated with transcription regulator activity (more detail) 23 18510698 Homo sapiens

GeneSigDB WIG001242 Genes involved in Sulfur amino acid metabolism (more detail) 23 NA Homo sapiens

MSigDB MOX015671 Genes associated with Computational Drug Signature Tyrphostin B42 Genes associated with Computational Drug Signature Tyrphostin B42, curated by the Drug Signature Dat (more detail) 23 25990557 Homo sapiens

DSigDB WIG001102 Genes involved in Pre NOTCH Transcription and Translation (more detail) 23 NA Homo sapiens

MSigDB FEX003207 Stomach Takada05 29genes Table 3. Genes showing high-level amplifications and homozygous deletions among 31 gastric cancer ce (more detail) 23 15723654 Homo sapiens

GeneSigDB MOX017176 Genes associated with Computational Drug Signature triamterene Genes associated with Computational Drug Signature triamterene, curated by the Drug Signature Databa (more detail) 23 25990557 Homo sapiens

DSigDB MOX004344 Genes associated with Computational Drug Signature METHYL PARATHION Genes associated with Computational Drug Signature METHYL PARATHION, curated by the Drug Signature D (more detail) 23 25990557 Homo sapiens

DSigDB IEI013547 Protein protein interactors of human gene TEK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TEK (SwissProt ID=Q0 (more detail) 32 17535438 Homo sapiens

I2D IEI000267 Protein protein interactors of human gene ADD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADD1 (SwissProt ID=P (more detail) 32 17535438 Homo sapiens

I2D IEI009460 Protein protein interactors of human gene PAK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAK4 (SwissProt ID=O (more detail) 32 17535438 Homo sapiens

I2D TAX026302 GO:0048701 biological process embryonic cranial skeleton morphogenesis The process in which the anatomical structures of the cranial skeleton are generated and organized d (more detail) 32 NA Homo sapiens

GOA TAX033575 GO:1904707 biological process positive regulation of vascular smooth muscle cell proliferation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell (more detail) 32 NA Homo sapiens

GOA TAX032258 GO:1901797 biological process negative regulation of signal transduction by p53 class mediator Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by (more detail) 32 NA Homo sapiens

GOA TAX026833 GO:0051150 biological process regulation of smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation. (more detail) 32 NA Homo sapiens

GOA IEI007661 Protein protein interactors of human gene MAP3K20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP3K20 (SwissProt I (more detail) 32 17535438 Homo sapiens

I2D TAX025490 GO:0046189 biological process phenol containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a phenol, any compound containing (more detail) 32 NA Homo sapiens

GOA MEX000411 Genes associated with Approved Drug chlorpromazine hydrochloride Genes associated with Approved Drug chlorpromazine hydrochloride, curated by the Drug Signature Data (more detail) 32 25990557 Homo sapiens

DSigDB WIG001621 Angiopoietin TIE2 Signaling Angiopoietin-TIE2 Signaling (more detail) 32 NA Homo sapiens

Protein Lounge WAG001455 hiv 1 nef: negative effector of fas and tnf HIV infection leads to drastic declines in CD4 T helper cells, in part through apoptosis of uninfect (more detail) 32 NA Homo sapiens

BioCarta MOX004463 Genes associated with Computational Drug Signature oxyphenbutazone Genes associated with Computational Drug Signature oxyphenbutazone, curated by the Drug Signature Da (more detail) 32 25990557 Homo sapiens

DSigDB MOX012889 Genes associated with Computational Drug Signature GNF Pf 3037 Genes associated with Computational Drug Signature GNF-Pf-3037, curated by the Drug Signature Databa (more detail) 32 25990557 Homo sapiens

DSigDB FEX002601 Prostate ChoVega05 44genes Table 2. Genes highly expressed in both cancer and normal libraries (more detail) 32 15529182 Homo sapiens

GeneSigDB MOX013134 Genes associated with Computational Drug Signature indirubin deriv. 7a Genes associated with Computational Drug Signature indirubin deriv. 7a, curated by the Drug Signatur (more detail) 32 25990557 Homo sapiens

DSigDB FOX000838 Genes in the cancer module 80 (more detail) 32 NA Homo sapiens

MSigDB IEI007696 Protein protein interactors of human gene MAPK8IP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPK8IP1 (SwissProt (more detail) 34 17535438 Homo sapiens

I2D FEX001446 Leukemia Lin06 37genes Table 1. Genes that were positively expressed in the adherent culture U937 cells with MSCs (more detail) 34 16780769 Homo sapiens

GeneSigDB IEI013714 Protein protein interactors of human gene TIMM13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TIMM13 (SwissProt ID (more detail) 34 17535438 Homo sapiens

I2D WAG001033 t cell receptor signaling pathway The T Cell Receptor plays a key role in the immune system. The specificity of the receptor is govern (more detail) 34 NA Homo sapiens

BioCarta FEX002600 Prostate Wu04 39genes Table 1 Genes up-regulated by NYK signals in FMS-NYK/DU145-6 cells (more detail) 34 15492251 Homo sapiens

GeneSigDB GEX001170 neoplasms neoplasms associated genes. PAGER constructed this gene set by grouping all genes which are associat (more detail) 34 NA Homo sapiens

GAD MOX002990 Genes associated with Computational Drug Signature Xanthohumol Genes associated with Computational Drug Signature Xanthohumol, curated by the Drug Signature Databa (more detail) 34 25990557 Homo sapiens

DSigDB MOX013261 Genes associated with Computational Drug Signature kaempferol Genes associated with Computational Drug Signature kaempferol, curated by the Drug Signature Databas (more detail) 34 25990557 Homo sapiens

DSigDB IEI005097 Protein protein interactors of human gene GBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GBP2 (SwissProt ID=P (more detail) 34 17535438 Homo sapiens

I2D IEI013007 Protein protein interactors of human gene SS18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SS18 (SwissProt ID=Q (more detail) 34 17535438 Homo sapiens

I2D TAX000412 Genes annotated by the GO term GO:0051348. Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus containing, or other groups, from a donor compound to an acceptor. (more detail) 34 NA Homo sapiens

MSigDB MOX015213 Genes associated with Computational Drug Signature SU 5416 Genes associated with Computational Drug Signature SU 5416, curated by the Drug Signature Database ( (more detail) 34 25990557 Homo sapiens

DSigDB IEI006991 Protein protein interactors of human gene KPNA6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KPNA6 (SwissProt ID= (more detail) 34 17535438 Homo sapiens

I2D WIG001230 Genes involved in Signal transduction by L1 (more detail) 34 NA Homo sapiens

MSigDB MOX016323 Genes associated with Computational Drug Signature leflunomide Genes associated with Computational Drug Signature leflunomide, curated by the Drug Signature Databa (more detail) 34 25990557 Homo sapiens

DSigDB IEI006150 Protein protein interactors of human gene IDE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IDE (SwissProt ID=P1 (more detail) 34 17535438 Homo sapiens

I2D IEI004246 Protein protein interactors of human gene ERC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERC1 (SwissProt ID=Q (more detail) 36 17535438 Homo sapiens

I2D TAX018213 GO:0010907 biological process positive regulation of glucose metabolic process Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic pr (more detail) 36 NA Homo sapiens

GOA TAX025681 GO:0046636 biological process negative regulation of alpha beta T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell acti (more detail) 36 NA Homo sapiens

GOA IEI001465 Protein protein interactors of human gene BTBD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BTBD2 (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D IEI009219 Protein protein interactors of human gene OAT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OAT (SwissProt ID=P0 (more detail) 36 17535438 Homo sapiens

I2D IEI004572 Protein protein interactors of human gene FANCL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FANCL (SwissProt ID= (more detail) 36 17535438 Homo sapiens

I2D IEI007966 Protein protein interactors of human gene MIB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MIB1 (SwissProt ID=Q (more detail) 36 17535438 Homo sapiens

I2D IEI002678 Protein protein interactors of human gene CLTA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLTA (SwissProt ID=P (more detail) 36 17535438 Homo sapiens

I2D TAX000268 Genes annotated by the GO term GO:0002252. Any process of the immune system that occurs as part of an immune response. (more detail) 36 NA Homo sapiens

MSigDB WIG001224 Genes involved in Signalling to ERKs (more detail) 36 NA Homo sapiens

MSigDB MOX000877 Genes associated with Computational Drug Signature Linalool Genes associated with Computational Drug Signature Linalool, curated by the Drug Signature Database (more detail) 36 25990557 Homo sapiens

DSigDB WIG000852 Genes involved in G1 Phase (more detail) 36 NA Homo sapiens

MSigDB WIG000069 Validated transcriptional targets of AP1 family members Fra1 and Fra2 (more detail) 36 NA Homo sapiens

MSigDB IEI004790 Protein protein interactors of human gene FKBP1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FKBP1A (SwissProt ID (more detail) 38 17535438 Homo sapiens

I2D IEI009543 Protein protein interactors of human gene PBRM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PBRM1 (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D TAX019003 GO:0016409 molecular function palmitoyltransferase activity Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule. (more detail) 38 NA Homo sapiens

GOA TAX025226 GO:0045687 biological process positive regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of glia cell differentiation. (more detail) 38 NA Homo sapiens

GOA TAX032651 GO:1902808 biological process positive regulation of cell cycle G1/S phase transition Any process that activates or increases the frequency, rate or extent of cell cycle G1/S phase trans (more detail) 38 NA Homo sapiens

GOA IEI005845 Protein protein interactors of human gene HINFP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HINFP (SwissProt ID= (more detail) 38 17535438 Homo sapiens

I2D MOX017684 Genes associated with Computational Drug Signature 2 Naphthoxyacetic acid Genes associated with Computational Drug Signature 2-Naphthoxyacetic acid, curated by the Drug Signa (more detail) 38 25990557 Homo sapiens

DSigDB TAX016500 GO:0006654 biological process phosphatidic acid biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative (more detail) 38 NA Homo sapiens

GOA TAX001334 Genes annotated by the GO term GO:0047485. Interacting selectively with a protein N terminus, the end of any peptide chain at which the 2 amino (or 2 imino) function of a constituent amino acid is not attached in peptide linkage to another amino acid residue. (more detail) 38 NA Homo sapiens

MSigDB TAX026586 GO:0050779 biological process RNA destabilization Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradativ (more detail) 25 NA Homo sapiens

GOA IEI014292 Protein protein interactors of human gene TRMO from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRMO (SwissProt ID=Q (more detail) 25 17535438 Homo sapiens

I2D TAX021979 GO:0033119 biological process negative regulation of RNA splicing Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing. (more detail) 25 NA Homo sapiens

GOA IEI014118 Protein protein interactors of human gene TPBG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TPBG (SwissProt ID=Q (more detail) 25 17535438 Homo sapiens

I2D IEI006765 Protein protein interactors of human gene KDM5A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM5A (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI005030 Protein protein interactors of human gene GALK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GALK1 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI004557 Protein protein interactors of human gene FAM98A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM98A (SwissProt ID (more detail) 25 17535438 Homo sapiens

I2D TAX026519 GO:0050685 biological process positive regulation of mRNA processing Any process that activates or increases the frequency, rate or extent of mRNA processing. (more detail) 25 NA Homo sapiens

GOA IEI004442 Protein protein interactors of human gene FAM120A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM120A (SwissProt I (more detail) 25 17535438 Homo sapiens

I2D IEI000058 Protein protein interactors of human gene ABCF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABCF2 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI014496 Protein protein interactors of human gene TUT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TUT1 (SwissProt ID=Q (more detail) 25 17535438 Homo sapiens

I2D IEI003971 Protein protein interactors of human gene EFEMP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFEMP1 (SwissProt ID (more detail) 25 17535438 Homo sapiens

I2D IEI010536 Protein protein interactors of human gene PRPF38A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRPF38A (SwissProt I (more detail) 25 17535438 Homo sapiens

I2D IEI002507 Protein protein interactors of human gene CHRAC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHRAC1 (SwissProt ID (more detail) 25 17535438 Homo sapiens

I2D IEI010233 Protein protein interactors of human gene POLR3C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR3C (SwissProt ID (more detail) 25 17535438 Homo sapiens

I2D IEI012588 Protein protein interactors of human gene SMARCA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMARCA1 (SwissProt I (more detail) 25 17535438 Homo sapiens

I2D MOX002959 Genes associated with Computational Drug Signature apicidin Genes associated with Computational Drug Signature apicidin, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB FEX000728 Breast Lin09 28genes Additional File 1-4. A list of genes corresponding to certain breast cancer related pathways;Cell Cy (more detail) 25 19695104 Homo sapiens

GeneSigDB WIG001269 Genes involved in TGF beta receptor signaling activates SMADs (more detail) 25 NA Homo sapiens

MSigDB TAX001064 Genes annotated by the GO term GO:0016407. Catalysis of the transfer of an acetyl group to an acceptor molecule. (more detail) 25 NA Homo sapiens

MSigDB MOX000350 Genes associated with Computational Drug Signature 5 hydroxy 1 (4 hydroxy 3 methoxyphenyl)decan 3 one Genes associated with Computational Drug Signature 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-on (more detail) 25 25990557 Homo sapiens

DSigDB MOX000212 Genes associated with Computational Drug Signature edaravone Genes associated with Computational Drug Signature edaravone, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB WAG001066 Trk receptor signaling mediated by the MAPK pathway (more detail) 25 NA Homo sapiens

NCI-Nature Curated MOX002449 Genes associated with Computational Drug Signature carnosol Genes associated with Computational Drug Signature carnosol, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB WIG000437 TNF/Stress Related Signaling TNF acts on several different signaling pathways through two cell surface receptors, TNFR1 and TNFR2 (more detail) 25 NA Homo sapiens

MSigDB IEI010780 Protein protein interactors of human gene PURB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PURB (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D TAX027942 GO:0060479 biological process lung cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire s (more detail) 20 NA Homo sapiens

GOA IEI005096 Protein protein interactors of human gene GBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GBP1 (SwissProt ID=P (more detail) 20 17535438 Homo sapiens

I2D IEI012788 Protein protein interactors of human gene SOX8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOX8 (SwissProt ID=P (more detail) 20 17535438 Homo sapiens

I2D IEI006039 Protein protein interactors of human gene HSD17B12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSD17B12 (SwissProt (more detail) 20 17535438 Homo sapiens

I2D IEI006353 Protein protein interactors of human gene IL3RA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL3RA (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX027949 GO:0060487 biological process lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial (more detail) 20 NA Homo sapiens

GOA TAX024321 GO:0043371 biological process negative regulation of CD4 positive, alpha beta T cell differentiation Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-b (more detail) 20 NA Homo sapiens

GOA IEI010642 Protein protein interactors of human gene PSMC3IP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMC3IP (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D IEI005016 Protein protein interactors of human gene GADD45B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GADD45B (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D IEI004000 Protein protein interactors of human gene EGR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EGR2 (SwissProt ID=P (more detail) 20 17535438 Homo sapiens

I2D IEI004654 Protein protein interactors of human gene FBXO44 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO44 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI005732 Protein protein interactors of human gene HBS1L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HBS1L (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI000723 Protein protein interactors of human gene APLF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APLF (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI008615 Protein protein interactors of human gene NCBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCBP2 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX034477 GO:2000104 biological process negative regulation of DNA dependent DNA replication Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA repl (more detail) 20 NA Homo sapiens

GOA TAX034907 GO:2000757 biological process negative regulation of peptidyl lysine acetylation Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetyla (more detail) 20 NA Homo sapiens

GOA IEI013357 Protein protein interactors of human gene TAF8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF8 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D TAX026032 GO:0048025 biological process negative regulation of mRNA splicing, via spliceosome Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal m (more detail) 20 NA Homo sapiens

GOA TAX021736 GO:0032727 biological process positive regulation of interferon alpha production Any process that activates or increases the frequency, rate, or extent of interferon-alpha productio (more detail) 20 NA Homo sapiens

GOA IEI008786 Protein protein interactors of human gene NFE2L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFE2L1 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI007571 Protein protein interactors of human gene MAFB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAFB (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI001241 Protein protein interactors of human gene BAZ2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BAZ2A (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI010931 Protein protein interactors of human gene RAD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD1 (SwissProt ID=O (more detail) 20 17535438 Homo sapiens

I2D MOX013772 Genes associated with Computational Drug Signature Molephantinin Genes associated with Computational Drug Signature Molephantinin, curated by the Drug Signature Data (more detail) 20 25990557 Homo sapiens

DSigDB MOX003534 Genes associated with Computational Drug Signature NVP BEZ235 Genes associated with Computational Drug Signature NVP-BEZ235, curated by the Drug Signature Databas (more detail) 20 25990557 Homo sapiens

DSigDB WIG001813 Cardiomyocyte Differentiation through BMP Receptors Cardiomyocyte Differentiation through BMP Receptors (more detail) 20 NA Homo sapiens

Protein Lounge WIG000806 Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity (more detail) 20 NA Homo sapiens

MSigDB MOX000173 Genes associated with Computational Drug Signature 1,2,9,10 tetramethoxyaporphine Genes associated with Computational Drug Signature 1,2,9,10-tetramethoxyaporphine, curated by the Dr (more detail) 20 25990557 Homo sapiens

DSigDB MOX004209 Genes associated with Computational Drug Signature HYPOCHLOROUS ACID Genes associated with Computational Drug Signature HYPOCHLOROUS ACID, curated by the Drug Signature (more detail) 20 25990557 Homo sapiens

DSigDB MOX012699 Genes associated with Computational Drug Signature Flavopiridol hydrochloride Genes associated with Computational Drug Signature Flavopiridol hydrochloride, curated by the Drug S (more detail) 20 25990557 Homo sapiens

DSigDB TAX000910 Genes annotated by the GO term GO:0000118. Complex that possesses histone deacetylase activity. (more detail) 20 NA Homo sapiens

MSigDB MOX001683 Genes associated with Computational Drug Signature Shogaol Genes associated with Computational Drug Signature Shogaol, curated by the Drug Signature Database ( (more detail) 20 25990557 Homo sapiens

DSigDB IEI000970 Protein protein interactors of human gene ASCC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASCC3 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI010236 Protein protein interactors of human gene POLR3F from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR3F (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D TAX025296 GO:0045830 biological process positive regulation of isotype switching Any process that activates or increases the frequency, rate or extent of isotype switching. (more detail) 27 NA Homo sapiens

GOA IEI001416 Protein protein interactors of human gene BPTF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BPTF (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D IEI012352 Protein protein interactors of human gene SLC25A22 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC25A22 (SwissProt (more detail) 27 17535438 Homo sapiens

I2D IEI015503 Protein protein interactors of human gene ZNF346 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF346 (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D TAX033374 GO:1904292 biological process regulation of ERAD pathway Any process that modulates the frequency, rate or extent of ERAD pathway. (more detail) 27 NA Homo sapiens

GOA IEI014302 Protein protein interactors of human gene TRMT2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRMT2A (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D IEI010681 Protein protein interactors of human gene PTBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTBP2 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI004115 Protein protein interactors of human gene ELP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELP2 (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D IEI011799 Protein protein interactors of human gene SARS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SARS2 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI000721 Protein protein interactors of human gene API5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene API5 (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D IEI011530 Protein protein interactors of human gene RPL34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL34 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D WIG000541 Histidine metabolism (more detail) 27 NA Homo sapiens

MSigDB WIG001972 Oxidative Stress Oxidative Stress (more detail) 27 NA Homo sapiens

WikiPathway WIG001386 Sorafenib Pharmacodynamics Mechanism of action of sorafenib (more detail) 27 NA Homo sapiens

PharmGKB WIG001079 Genes involved in PIP3 activates AKT signaling (more detail) 27 NA Homo sapiens

MSigDB WIG000223 Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. na (more detail) 27 NA Homo sapiens

MSigDB GEX167986 Thyroid hormone levels A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the (more detail) 27 23408906 Homo sapiens

GWAS Catalog MOX001458 Genes associated with Computational Drug Signature 60282 87 3 Genes associated with Computational Drug Signature 60282-87-3, curated by the Drug Signature Databas (more detail) 27 25990557 Homo sapiens

DSigDB FOX000209 Neighborhood of SMC1L1 Neighborhood of SMC1L1 NULL in the GNF2 expression compendium (more detail) 27 NA Homo sapiens

MSigDB TAX000222 Genes annotated by the GO term GO:0000082. Progression from G1 phase to S phase of the mitotic cell cycle. (more detail) 27 NA Homo sapiens

MSigDB WIG000070 Glypican 1 network (more detail) 27 NA Homo sapiens

MSigDB MOX001116 Genes associated with Computational Drug Signature 3 methyladenine Genes associated with Computational Drug Signature 3-methyladenine, curated by the Drug Signature Da (more detail) 27 25990557 Homo sapiens

DSigDB WIG000920 Genes involved in Interleukin receptor SHC signaling (more detail) 27 NA Homo sapiens

MSigDB IEI002329 Protein protein interactors of human gene CENPB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CENPB (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI004023 Protein protein interactors of human gene EIF2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF2A (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI008172 Protein protein interactors of human gene MRM3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRM3 (SwissProt ID=Q (more detail) 29 17535438 Homo sapiens

I2D IEI007004 Protein protein interactors of human gene KRR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KRR1 (SwissProt ID=Q (more detail) 29 17535438 Homo sapiens

I2D IEI003996 Protein protein interactors of human gene EGLN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EGLN1 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI010770 Protein protein interactors of human gene PTTG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTTG1 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI007698 Protein protein interactors of human gene MAPK8IP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPK8IP3 (SwissProt (more detail) 29 17535438 Homo sapiens

I2D IEI006405 Protein protein interactors of human gene INO80E from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INO80E (SwissProt ID (more detail) 29 17535438 Homo sapiens

I2D IEI004612 Protein protein interactors of human gene FBXL12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXL12 (SwissProt ID (more detail) 29 17535438 Homo sapiens

I2D FEX000085 BoneMarrow Zhan02 30genes Table 2. The 30 most differentially expressed genes in a comparison of MM1 and MM4 subgroups (more detail) 29 11861292 Homo sapiens

GeneSigDB WIG000085 IGF1 pathway (more detail) 29 NA Homo sapiens

MSigDB MOX003032 Genes associated with Computational Drug Signature Tyrphostin B48 Genes associated with Computational Drug Signature Tyrphostin B48, curated by the Drug Signature Dat (more detail) 29 25990557 Homo sapiens

DSigDB MOX005144 Genes associated with Computational Drug Signature gsno Genes associated with Computational Drug Signature gsno, curated by the Drug Signature Database (DSi (more detail) 29 25990557 Homo sapiens

DSigDB MEX000332 Genes associated with Approved Drug triamterene Genes associated with Approved Drug triamterene, curated by the Drug Signature Database (DSigDB). (more detail) 29 25990557 Homo sapiens

DSigDB MOX003399 Genes associated with Computational Drug Signature dichlorvos Genes associated with Computational Drug Signature dichlorvos, curated by the Drug Signature Databas (more detail) 29 25990557 Homo sapiens

DSigDB WAG001269 IGF1 pathway (more detail) 29 NA Homo sapiens

NCI-Nature Curated MOX006330 Genes associated with Computational Drug Signature 7 AMINO 4 HYDROXY 2 NAPHTHALENESULFONIC ACID Genes associated with Computational Drug Signature 7-AMINO-4-HYDROXY-2-NAPHTHALENESULFONIC ACID, cur (more detail) 29 25990557 Homo sapiens

DSigDB WIG000414 Links between Pyk2 and Map Kinases This diagram is a compilation of Pyk2 effort cascades. In specific cell types the receptor and effoe (more detail) 29 NA Homo sapiens

MSigDB TAX022795 GO:0035269 biological process protein O linked mannosylation The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl (more detail) 14 NA Homo sapiens

GOA IEI013752 Protein protein interactors of human gene TLE4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLE4 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D TAX017605 GO:0009214 biological process cyclic nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide (more detail) 14 NA Homo sapiens

GOA TAX019608 GO:0019104 molecular function DNA N glycosylase activity Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target d (more detail) 14 NA Homo sapiens

GOA TAX020375 GO:0030207 biological process chondroitin sulfate catabolic process The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of (more detail) 14 NA Homo sapiens

GOA TAX025616 GO:0046519 biological process sphingoid metabolic process The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sph (more detail) 14 NA Homo sapiens

GOA TAX015333 GO:0004707 molecular function MAP kinase activity Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphoryla (more detail) 14 NA Homo sapiens

GOA IEI005115 Protein protein interactors of human gene GCM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GCM1 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI008654 Protein protein interactors of human gene NDFIP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NDFIP2 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI010526 Protein protein interactors of human gene PROS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PROS1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI011397 Protein protein interactors of human gene RNF144A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF144A (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI005284 Protein protein interactors of human gene GMFB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GMFB (SwissProt ID=P (more detail) 14 17535438 Homo sapiens

I2D TAX017309 GO:0008499 molecular function UDP galactose:beta N acetylglucosamine beta 1,3 galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosam (more detail) 14 NA Homo sapiens

GOA TAX022515 GO:0034472 biological process snRNA 3' end processing Any process involved in forming the mature 3' end of an snRNA molecule. (more detail) 14 NA Homo sapiens

GOA TAX017528 GO:0009130 biological process pyrimidine nucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphat (more detail) 14 NA Homo sapiens

GOA TAX021056 GO:0031573 biological process intra S DNA damage checkpoint A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention (more detail) 14 NA Homo sapiens

GOA IEI011326 Protein protein interactors of human gene RIOK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RIOK1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX022133 GO:0033549 molecular function MAP kinase phosphatase activity Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate. (more detail) 14 NA Homo sapiens

GOA TAX022760 GO:0035196 biological process production of miRNAs involved in gene silencing by miRNA Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily s (more detail) 14 NA Homo sapiens

GOA TAX017515 GO:0009113 biological process purine nucleobase biosynthetic process The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two (more detail) 14 NA Homo sapiens

GOA TAX019085 GO:0016540 biological process protein autoprocessing Processing which a protein carries out itself. This involves actions such as the autolytic removal o (more detail) 14 NA Homo sapiens

GOA TAX024246 GO:0043240 cellular component Fanconi anaemia nuclear complex A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F) (more detail) 14 NA Homo sapiens

GOA TAX014760 GO:0003688 molecular function DNA replication origin binding Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of (more detail) 14 NA Homo sapiens

GOA TAX032980 GO:1903513 biological process endoplasmic reticulum to cytosol transport The directed movement of substances from endoplasmic reticulum to cytosol. (more detail) 14 NA Homo sapiens

GOA TAX028793 GO:0070198 biological process protein localization to chromosome, telomeric region Any process in which a protein is transported to, or maintained at, the telomeric region of a chromo (more detail) 14 NA Homo sapiens

GOA IEI011375 Protein protein interactors of human gene RNF103 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF103 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI004868 Protein protein interactors of human gene FOXH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXH1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI007094 Protein protein interactors of human gene KSR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KSR2 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI005680 Protein protein interactors of human gene H3 5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H3-5 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D TAX022068 GO:0033276 cellular component transcription factor TFTC complex A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, bu (more detail) 14 NA Homo sapiens

GOA TAX025532 GO:0046341 biological process CDP diacylglycerol metabolic process The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substanc (more detail) 14 NA Homo sapiens

GOA TAX028525 GO:0061647 biological process histone H3 K9 modification The modification of histone H3 at a lysine in position 9 of the histone. (more detail) 14 NA Homo sapiens

GOA TAX016343 GO:0006450 biological process regulation of translational fidelity Any process that modulates the ability of the translational apparatus to interpret the genetic code. (more detail) 14 NA Homo sapiens

GOA TAX021563 GO:0032454 molecular function histone demethylase activity (H3 K9 specific) Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = s (more detail) 14 NA Homo sapiens

GOA TAX019741 GO:0019511 biological process peptidyl proline hydroxylation The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline. (more detail) 14 NA Homo sapiens

GOA TAX025406 GO:0046036 biological process CTP metabolic process The chemical reactions and pathways involving CTP, cytidine triphosphate. (more detail) 14 NA Homo sapiens

GOA TAX026437 GO:0050321 molecular function tau protein kinase activity Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein. (more detail) 14 NA Homo sapiens

GOA TAX025821 GO:0046940 biological process nucleoside monophosphate phosphorylation The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a (more detail) 14 NA Homo sapiens

GOA IEI010275 Protein protein interactors of human gene POU1F1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POU1F1 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI004082 Protein protein interactors of human gene ELF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELF2 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D TAX031164 GO:0098847 molecular function sequence specific single stranded DNA binding Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composi (more detail) 14 NA Homo sapiens

GOA TAX019632 GO:0019206 molecular function nucleoside kinase activity Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate. (more detail) 14 NA Homo sapiens

GOA TAX020741 GO:0030970 biological process retrograde protein transport, ER to cytosol The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytoso (more detail) 14 NA Homo sapiens

GOA WEX000006 Arginine Metabolism The genes related to arginine metabolism (metabolism) in tumor, immune, stroma using next-generation (more detail) 14 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas TAX022896 GO:0035497 molecular function cAMP response element binding Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palin (more detail) 14 NA Homo sapiens

GOA MEX002082 Genes associated with Kinase Inhibitor GW795493X Genes associated with Kinase Inhibitor GW795493X, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX007338 Genes associated with Computational Drug Signature BMS 536924 Genes associated with Computational Drug Signature BMS-536924, curated by the Drug Signature Databas (more detail) 14 25990557 Homo sapiens

DSigDB TAX014066 GO:0002098 biological process tRNA wobble uridine modification The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified. (more detail) 14 NA Homo sapiens

GOA TAX016526 GO:0006684 biological process sphingomyelin metabolic process The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholi (more detail) 14 NA Homo sapiens

GOA TAX016250 GO:0006309 biological process apoptotic DNA fragmentation The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of (more detail) 14 NA Homo sapiens

GOA PEX002210 Pro isomerase: Cyclophilin type peptidyl prolyl cis trans isomerase/CLD The peptidyl-prolyl cis-trans isomerases, also known as cyclophilins, share this domain of about 109 (more detail) 14 NA Homo sapiens

Pfam WAG000639 map kinase inactivation of smrt corepressor Corepressors are coregulators that interact with transcriptiol silencers in a variety of pathways su (more detail) 14 NA Homo sapiens

BioCarta WAG001539 Polymerase switching (more detail) 14 NA Homo sapiens

Reactome WIG000292 Classical Complement Pathway The complement system is part of the defense against invading cells and is composed of about twenty (more detail) 14 NA Homo sapiens

MSigDB FOX000669 Genes in the cancer module 360 (more detail) 14 NA Homo sapiens

MSigDB MAX002048 Composition of the 2 MDa human STAGA complex containing KAT2A [GeneID=2648]. Transcription in eukaryotes is a tightly regulated, multistep process. Gene-specific transcriptional (more detail) 14 NA Homo sapiens

MSigDB WIG000677 Genes involved in Acyl chain remodelling of PS (more detail) 14 NA Homo sapiens

MSigDB MEX001964 Genes associated with Kinase Inhibitor Kinome 859 Genes associated with Kinase Inhibitor Kinome_859, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX001709 Genes associated with Kinase Inhibitor Kinome 1216 Genes associated with Kinase Inhibitor Kinome_1216, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002415 Genes associated with Kinase Inhibitor Ceritinib Genes associated with Kinase Inhibitor Ceritinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002123 Genes associated with Kinase Inhibitor Fostamatinib Genes associated with Kinase Inhibitor Fostamatinib, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens

DSigDB MOX010842 Genes associated with Computational Drug Signature CHEMBL475540 Genes associated with Computational Drug Signature CHEMBL475540, curated by the Drug Signature Datab (more detail) 14 25990557 Homo sapiens

DSigDB TAX016401 GO:0006534 biological process cysteine metabolic process The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid. (more detail) 14 NA Homo sapiens

GOA TAX016205 GO:0006241 biological process CTP biosynthetic process The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate. (more detail) 14 NA Homo sapiens

GOA WAG000405 Keratan sulfate biosynthesis Keratan sulfate (KS) is a glycosaminoglycan with the basic disaccharide unit of N-acetyllactosamine, (more detail) 14 NA Homo sapiens

KEGG WAG000444 Atypical NF kappaB pathway (more detail) 14 NA Homo sapiens

NCI-Nature Curated WAG000252 RXR and RAR hetrodimerization with other nuclear receptor (more detail) 14 NA Homo sapiens

NCI-Nature Curated WAG000510 Polymerase switching on the C strand of the telomere (more detail) 14 NA Homo sapiens

Reactome TAX013438 GO:0000479 biological process endonucleolytic cleavage of tricistronic rRNA transcript (SSU rRNA, 5.8S rRNA, LSU rRNA) Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcrip (more detail) 14 NA Homo sapiens

GOA WIG000981 Genes involved in Metabolism of polyamines (more detail) 14 NA Homo sapiens

MSigDB WIG000179 Ras signaling in the CD4+ TCR pathway (more detail) 14 NA Homo sapiens

MSigDB MEX002228 Genes associated with Kinase Inhibitor Kinome 3196 Genes associated with Kinase Inhibitor Kinome_3196, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002283 Genes associated with Kinase Inhibitor Kinome 708 Genes associated with Kinase Inhibitor Kinome_708, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002135 Genes associated with Kinase Inhibitor Bisindolylmaleimide XI, HCl Genes associated with Kinase Inhibitor Bisindolylmaleimide XI, HCl, curated by the Drug Signature Da (more detail) 14 25990557 Homo sapiens

DSigDB WAG001022 phosphorylation of mek1 by cdk5/p35 down regulates the map kinase pathway Map kises transduce responses to extracellular sigls by a variety of routes, and communicate with ot (more detail) 14 NA Homo sapiens

BioCarta FEX001363 Leukemia Bal05 15genes Table 6 Deregulation of DNA repair proteins in acutely HTLV-1 transformed cells (more detail) 14 15896717 Homo sapiens

GeneSigDB TAX001109 Genes annotated by the GO term GO:0016831. Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound. (more detail) 14 NA Homo sapiens

MSigDB TAX001363 Genes annotated by the GO term GO:0003705. Functions to initiate or regulate RNA polymerase II transcription by binding an enhancer region of DNA. (more detail) 14 NA Homo sapiens

MSigDB MEX001718 Genes associated with Kinase Inhibitor Kinome 450 Genes associated with Kinase Inhibitor Kinome_450, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002094 Genes associated with Kinase Inhibitor Tasocitinib Genes associated with Kinase Inhibitor Tasocitinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX001207 Genes associated with Kinase Inhibitor Kinome 439 Genes associated with Kinase Inhibitor Kinome_439, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB WIG000906 Genes involved in Homologous recombination repair of replication independent double strand breaks (more detail) 14 NA Homo sapiens

MSigDB FOX000733 Genes in the cancer module 445 (more detail) 14 NA Homo sapiens

MSigDB WIG000530 Glycosaminoglycan biosynthesis keratan sulfate (more detail) 14 NA Homo sapiens

MSigDB WIG001257 Genes involved in Synthesis of very long chain fatty acyl CoAs (more detail) 14 NA Homo sapiens

MSigDB WIG001105 Genes involved in Processing of Intronless Pre mRNAs (more detail) 14 NA Homo sapiens

MSigDB MEX001318 Genes associated with Kinase Inhibitor Ibrutinib Genes associated with Kinase Inhibitor Ibrutinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX001945 Genes associated with Kinase Inhibitor Kinome 239 Genes associated with Kinase Inhibitor Kinome_239, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX001731 Genes associated with Kinase Inhibitor TCMDC 141371 Genes associated with Kinase Inhibitor TCMDC-141371, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens

DSigDB MEX002419 Genes associated with Kinase Inhibitor Ibrutinib Genes associated with Kinase Inhibitor Ibrutinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB PEX002160 HLH: Helix loop helix DNA binding domain (more detail) 14 NA Homo sapiens

Pfam TAX013251 GO:0000098 biological process sulfur amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, com (more detail) 14 NA Homo sapiens

GOA WIG000533 Glycosphingolipid biosynthesis globo series (more detail) 14 NA Homo sapiens

MSigDB WIG001315 Genes involved in Viral Messenger RNA Synthesis (more detail) 14 NA Homo sapiens

MSigDB WIG001235 Genes involved in SOS mediated signalling (more detail) 14 NA Homo sapiens

MSigDB TAX001044 Genes annotated by the GO term GO:0005669. A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters. (more detail) 14 NA Homo sapiens

MSigDB WIG000783 Genes involved in Cytosolic sulfonation of small molecules (more detail) 14 NA Homo sapiens

MSigDB WIG000982 Genes involved in Metabolism of porphyrins (more detail) 14 NA Homo sapiens

MSigDB WIG000838 Genes involved in FGFR1 ligand binding and activation (more detail) 14 NA Homo sapiens

MSigDB WIG001155 Genes involved in Repair synthesis for gap filling by DNA polymerase in TC NER (more detail) 14 NA Homo sapiens

MSigDB MEX002375 Genes associated with Kinase Inhibitor dorsomorphin Genes associated with Kinase Inhibitor dorsomorphin, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens

DSigDB MEX002412 Genes associated with Kinase Inhibitor Tofacitinib Genes associated with Kinase Inhibitor Tofacitinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB PEX001442 LSM: LSM domain The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/ (more detail) 14 NA Homo sapiens

Pfam WAG001542 Processing of Intronless Pre mRNAs (more detail) 14 NA Homo sapiens

Reactome WIG000912 Genes involved in Hyaluronan metabolism (more detail) 14 NA Homo sapiens

MSigDB MEX002204 Genes associated with Kinase Inhibitor curcumin Genes associated with Kinase Inhibitor curcumin, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002269 Genes associated with Kinase Inhibitor 841290 80 0 Genes associated with Kinase Inhibitor 841290-80-0, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002015 Genes associated with Kinase Inhibitor BS 181 Genes associated with Kinase Inhibitor BS-181, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX002361 Genes associated with Kinase Inhibitor CHEMBL495696 Genes associated with Kinase Inhibitor CHEMBL495696, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens

DSigDB MEX002083 Genes associated with Kinase Inhibitor Go 6976 Genes associated with Kinase Inhibitor Go 6976, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MEX000147 Genes associated with Approved Drug gemfibrozil Genes associated with Approved Drug gemfibrozil, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB TAX016093 GO:0006047 biological process UDP N acetylglucosamine metabolic process The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-ace (more detail) 14 NA Homo sapiens

GOA WAG001326 MicroRNA biogenesis (more detail) 14 NA Homo sapiens

Reactome WAG001365 Removal of the Flap Intermediate (more detail) 14 NA Homo sapiens

Reactome TAX001142 Genes annotated by the GO term GO:0003887. Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer. (more detail) 14 NA Homo sapiens

MSigDB TAX000236 Genes annotated by the GO term GO:0009064. The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. (more detail) 14 NA Homo sapiens

MSigDB WIG001000 Genes involved in mRNA Decay by 5' to 3' Exoribonuclease (more detail) 14 NA Homo sapiens

MSigDB WIG001041 Genes involved in N Glycan antennae elongation (more detail) 14 NA Homo sapiens

MSigDB MAX003281 An assortment of osteoblast transcriptional regulators. The use of genetically manipulated mouse models, gene and protein discovery and the cataloguing of g (more detail) 14 NA Homo sapiens

MSigDB IEI008932 Protein protein interactors of human gene NOL6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOL6 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D TAX027745 GO:0060216 biological process definitive hemopoiesis A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem ce (more detail) 17 NA Homo sapiens

GOA IEI011906 Protein protein interactors of human gene SDF2L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SDF2L1 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI003912 Protein protein interactors of human gene ECD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ECD (SwissProt ID=O9 (more detail) 17 17535438 Homo sapiens

I2D IEI008264 Protein protein interactors of human gene MS4A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MS4A2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI014818 Protein protein interactors of human gene UTP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UTP4 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D TAX015968 GO:0005847 cellular component mRNA cleavage and polyadenylation specificity factor complex A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence el (more detail) 17 NA Homo sapiens

GOA TAX024534 GO:0043923 biological process positive regulation by host of viral transcription Any process in which a host organism activates or increases the frequency, rate or extent of viral t (more detail) 17 NA Homo sapiens

GOA TAX022718 GO:0035067 biological process negative regulation of histone acetylation Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an ace (more detail) 17 NA Homo sapiens

GOA TAX028044 GO:0060644 biological process mammary gland epithelial cell differentiation The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelia (more detail) 17 NA Homo sapiens

GOA TAX033408 GO:1904355 biological process positive regulation of telomere capping Any process that activates or increases the frequency, rate or extent of telomere capping. (more detail) 17 NA Homo sapiens

GOA IEI014603 Protein protein interactors of human gene UBE4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE4A (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI004329 Protein protein interactors of human gene ETV4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ETV4 (SwissProt ID=P (more detail) 17 17535438 Homo sapiens

I2D IEI010099 Protein protein interactors of human gene PLK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLK3 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D IEI009126 Protein protein interactors of human gene NUAK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUAK2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI003569 Protein protein interactors of human gene DIS3L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIS3L (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX033139 GO:1903798 biological process regulation of production of miRNAs involved in gene silencing by miRNA Any process that modulates the frequency, rate or extent of production of miRNAs involved in gene si (more detail) 17 NA Homo sapiens

GOA WIG000796 Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) (more detail) 17 NA Homo sapiens

MSigDB WAG000661 p38 MAPK signaling pathway (more detail) 17 NA Homo sapiens

NCI-Nature Curated WIG000316 Role of Erk5 in Neuronal Survival Axons extend significant distances to innervate target tissues. At the site of innervation, target t (more detail) 17 NA Homo sapiens

MSigDB WIG000259 Tumor Suppressor Arf Inhibits Ribosomal Biogenesis Cyclin-dependent kinase inhibitor-2A (CDKN2A) goes by the colloquial designation p16, which is somet (more detail) 17 NA Homo sapiens

MSigDB WIG000768 Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (more detail) 17 NA Homo sapiens

MSigDB WIG000204 PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. na (more detail) 17 NA Homo sapiens

MSigDB WAG000217 nerve growth factor pathway (ngf) Nerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and prolifera (more detail) 17 NA Homo sapiens

BioCarta MOX002578 Genes associated with Computational Drug Signature benzo[a]pyrene 7,8 dione Genes associated with Computational Drug Signature benzo[a]pyrene-7,8-dione, curated by the Drug Sig (more detail) 17 25990557 Homo sapiens

DSigDB MOX012704 Genes associated with Computational Drug Signature floxuridine Genes associated with Computational Drug Signature floxuridine, curated by the Drug Signature Databa (more detail) 17 25990557 Homo sapiens

DSigDB TAX001027 Genes annotated by the GO term GO:0030880. Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits. (more detail) 17 NA Homo sapiens

MSigDB MEX000872 Genes associated with Approved Drug melphalan Genes associated with Approved Drug melphalan, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB WIG001156 Genes involved in Resolution of AP sites via the multiple nucleotide patch replacement pathway (more detail) 17 NA Homo sapiens

MSigDB WIG000731 Genes involved in Branched chain amino acid catabolism (more detail) 17 NA Homo sapiens

MSigDB WIG000795 Genes involved in Destabilization of mRNA by KSRP (more detail) 17 NA Homo sapiens

MSigDB TAX000981 Genes annotated by the GO term GO:0055029. A protein complex, located in the nucleus, that possesses DNA directed RNA polymerase activity. (more detail) 17 NA Homo sapiens

MSigDB FEX001589 Leukemia Sanchez Guijo08 19genes SuppTable2o Genes involved in protein phosphorilation (more detail) 17 18722011 Homo sapiens

GeneSigDB WIG002024 Sulfation Biotransformation Reaction Sulfation Biotransformation Reaction (more detail) 17 NA Homo sapiens

WikiPathway TAX000881 Genes annotated by the GO term GO:0000428. A protein complex that possesses DNA directed RNA polymerase activity. (more detail) 17 NA Homo sapiens

MSigDB MEX001914 Genes associated with Kinase Inhibitor 929095 18 1 Genes associated with Kinase Inhibitor 929095-18-1, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB TAX017867 GO:0010165 biological process response to X ray Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 31 NA Homo sapiens

GOA IEI006769 Protein protein interactors of human gene KDM6A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM6A (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI003424 Protein protein interactors of human gene DDX41 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX41 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D WEX000003 Androgen Signaling The genes related to androgen signaling (signaling pathways) in tumor using next-generation sequence (more detail) 31 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI008208 Protein protein interactors of human gene MRPL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPL4 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI010349 Protein protein interactors of human gene PPP1R15A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R15A (SwissProt (more detail) 31 17535438 Homo sapiens

I2D IEI011100 Protein protein interactors of human gene RBMS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBMS1 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D TAX028704 GO:0070059 biological process intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic (more detail) 31 NA Homo sapiens

GOA IEI007477 Protein protein interactors of human gene LSM7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSM7 (SwissProt ID=Q (more detail) 31 17535438 Homo sapiens

I2D MOX001282 Genes associated with Computational Drug Signature 2,2',3,4,4',5' HEXACHLOROBIPHENYL Genes associated with Computational Drug Signature 2,2',3,4,4',5'-HEXACHLOROBIPHENYL, curated by the (more detail) 31 25990557 Homo sapiens

DSigDB MOX004988 Genes associated with Computational Drug Signature amlodipine Genes associated with Computational Drug Signature amlodipine, curated by the Drug Signature Databas (more detail) 31 25990557 Homo sapiens

DSigDB TAX000851 Genes annotated by the GO term GO:0000785. The ordered and organized complex of DNA and protein that forms the chromosome. (more detail) 31 NA Homo sapiens

MSigDB MOX000707 Genes associated with Computational Drug Signature Plumbagin Genes associated with Computational Drug Signature Plumbagin, curated by the Drug Signature Database (more detail) 31 25990557 Homo sapiens

DSigDB WIG000735 Genes involved in CD28 co stimulation (more detail) 31 NA Homo sapiens

MSigDB TAX000082 Genes annotated by the GO term GO:0022411. A cellular process that results in the breakdown of a part of the cell. (more detail) 31 NA Homo sapiens

MSigDB MOX012904 Genes associated with Computational Drug Signature GNF Pf 78 Genes associated with Computational Drug Signature GNF-Pf-78, curated by the Drug Signature Database (more detail) 31 25990557 Homo sapiens

DSigDB MOX003654 Genes associated with Computational Drug Signature ALUMINUM Genes associated with Computational Drug Signature ALUMINUM, curated by the Drug Signature Database (more detail) 31 25990557 Homo sapiens

DSigDB FEX002337 Lymphoma Compagno09 genes Table S2. List of NF-kB related genes analyzed (more detail) 31 19412164 Homo sapiens

GeneSigDB WIG001782 BAFF Receptors in B Cell Signaling BAFF Receptors in B-Cell Signaling (more detail) 31 NA Homo sapiens

Protein Lounge TAX029252 GO:0071010 cellular component prespliceosome A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequ (more detail) 22 NA Homo sapiens

GOA IEI012162 Protein protein interactors of human gene SH3RF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH3RF1 (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D WEX000086 Proteotoxic Stress The genes related to proteotoxic stress (cell function) in tumor using next-generation sequencer (NG (more detail) 22 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI004248 Protein protein interactors of human gene ERCC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERCC1 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI002977 Protein protein interactors of human gene CREBZF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CREBZF (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D IEI011475 Protein protein interactors of human gene RORB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RORB (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI004882 Protein protein interactors of human gene FOXO4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXO4 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI009751 Protein protein interactors of human gene PER1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PER1 (SwissProt ID=O (more detail) 22 17535438 Homo sapiens

I2D IEI007410 Protein protein interactors of human gene LRR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRR1 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI013348 Protein protein interactors of human gene TAF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF3 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D TAX017928 GO:0010467 biological process gene expression The process in which a gene's sequence is converted into a mature gene product or products (proteins (more detail) 22 NA Homo sapiens

GOA IEI006917 Protein protein interactors of human gene KLHL13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHL13 (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D IEI011636 Protein protein interactors of human gene RRN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRN3 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D WIG001137 Genes involved in Regulation of Hypoxia inducible Factor (HIF) by Oxygen (more detail) 22 NA Homo sapiens

MSigDB MEX000955 Genes associated with Approved Drug isotretinoin Genes associated with Approved Drug isotretinoin, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB FEX000744 Breast Speers09 24genes Supplementary Table 3. Kinases overexpressed in ER-positive breast cancer (more detail) 22 19808870 Homo sapiens

GeneSigDB WIG000287 Ceramide Signaling Pathway Over 1,000 papers and reviews have been written about the role of ceramide in the production of prog (more detail) 22 NA Homo sapiens

MSigDB WIG000341 Role of ERBB2 in Signal Transduction and Oncology Her2 or ERBB2 belongs to a class of proteins having high homology with epidermal growth factor recep (more detail) 22 NA Homo sapiens

MSigDB FOX000626 Genes in the cancer module 310 (more detail) 22 NA Homo sapiens

MSigDB WAG000433 control of gene expression by vitamin d receptor The vitamin D receptor, VDR is the mediator of all genomic actions of vitamin D3 and its alogs. It b (more detail) 22 NA Homo sapiens

BioCarta FEX002807 StemCell Shim04 23genes Table 4. Transcription factor-associated genes (more detail) 22 15246160 Homo sapiens

GeneSigDB WAG001373 snRNP Assembly (more detail) 22 NA Homo sapiens

Reactome FEX000557 Breast Lauss08 25genes Table 2 Top 25 genes a subset of the 374 gene list of breast cancer recurrence genes. These are a c (more detail) 22 17899371 Homo sapiens

GeneSigDB MOX006025 Genes associated with Computational Drug Signature 4 aminophenol Genes associated with Computational Drug Signature 4-aminophenol, curated by the Drug Signature Data (more detail) 22 25990557 Homo sapiens

DSigDB MOX004790 Genes associated with Computational Drug Signature triamterene Genes associated with Computational Drug Signature triamterene, curated by the Drug Signature Databa (more detail) 22 25990557 Homo sapiens

DSigDB MOX004153 Genes associated with Computational Drug Signature GLYCYRRHETINIC ACID Genes associated with Computational Drug Signature GLYCYRRHETINIC ACID, curated by the Drug Signatur (more detail) 22 25990557 Homo sapiens

DSigDB FEX000106 BoneMarrow Abraham05 26genes Table 4. Genes with significantly higher average gene expression in AL plasma cells compared to MM (more detail) 22 15388584 Homo sapiens

GeneSigDB FEX001455 Leukemia Camos06 25genes Table 1a Genes with a significant differential expression level (overexpressed and underexpressed) i (more detail) 22 16849538 Homo sapiens

GeneSigDB WAG000447 Alpha synuclein signaling (more detail) 22 NA Homo sapiens

NCI-Nature Curated MOX016032 Genes associated with Computational Drug Signature Cladribine Genes associated with Computational Drug Signature Cladribine, curated by the Drug Signature Databas (more detail) 22 25990557 Homo sapiens

DSigDB MOX016605 Genes associated with Computational Drug Signature Crizotinib Genes associated with Computational Drug Signature Crizotinib, curated by the Drug Signature Databas (more detail) 22 25990557 Homo sapiens

DSigDB FEX003370 Viral Sun01 27genes Cell Cycle Related TABLE 3. Expression Profile of Cell Cycle-Related Genes in BC-2 Cells and Its Effect by MAP30 (more detail) 22 11573962 Homo sapiens

GeneSigDB TAX001257 Genes annotated by the GO term GO:0003729. Interacting selectively with pre messenger RNA (pre mRNA) or messenger RNA (mRNA). (more detail) 22 NA Homo sapiens

MSigDB IEI000964 Protein protein interactors of human gene ASB6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASB6 (SwissProt ID=Q (more detail) 33 17535438 Homo sapiens

I2D IEI004030 Protein protein interactors of human gene EIF2B3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF2B3 (SwissProt ID (more detail) 33 17535438 Homo sapiens

I2D IEI007686 Protein protein interactors of human gene MAPK12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPK12 (SwissProt ID (more detail) 33 17535438 Homo sapiens

I2D IEI013192 Protein protein interactors of human gene SUFU from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUFU (SwissProt ID=Q (more detail) 33 17535438 Homo sapiens

I2D IEI011382 Protein protein interactors of human gene RNF115 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF115 (SwissProt ID (more detail) 33 17535438 Homo sapiens

I2D IEI000922 Protein protein interactors of human gene ARR3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARR3 (SwissProt ID=P (more detail) 33 17535438 Homo sapiens

I2D IEI002250 Protein protein interactors of human gene CDK20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK20 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI014791 Protein protein interactors of human gene USP45 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP45 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D IEI008207 Protein protein interactors of human gene MRPL39 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPL39 (SwissProt ID (more detail) 33 17535438 Homo sapiens

I2D IEI007131 Protein protein interactors of human gene LAMP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LAMP1 (SwissProt ID= (more detail) 33 17535438 Homo sapiens

I2D MOX004117 Genes associated with Computational Drug Signature flutamide Genes associated with Computational Drug Signature flutamide, curated by the Drug Signature Database (more detail) 33 25990557 Homo sapiens

DSigDB MEX000601 Genes associated with Approved Drug lovastatin Genes associated with Approved Drug lovastatin, curated by the Drug Signature Database (DSigDB). (more detail) 33 25990557 Homo sapiens

DSigDB MOX004099 Genes associated with Computational Drug Signature flufenamic acid Genes associated with Computational Drug Signature flufenamic acid, curated by the Drug Signature Da (more detail) 33 25990557 Homo sapiens

DSigDB MOX004016 Genes associated with Computational Drug Signature dobutamine Genes associated with Computational Drug Signature dobutamine, curated by the Drug Signature Databas (more detail) 33 25990557 Homo sapiens

DSigDB MOX002374 Genes associated with Computational Drug Signature fluticasone Genes associated with Computational Drug Signature fluticasone, curated by the Drug Signature Databa (more detail) 33 25990557 Homo sapiens

DSigDB MOX004623 Genes associated with Computational Drug Signature Riboflavine Genes associated with Computational Drug Signature Riboflavine, curated by the Drug Signature Databa (more detail) 33 25990557 Homo sapiens

DSigDB MOX002217 Genes associated with Computational Drug Signature CADMIUM SELENIDE Genes associated with Computational Drug Signature CADMIUM SELENIDE, curated by the Drug Signature D (more detail) 33 25990557 Homo sapiens

DSigDB WIG001806 C. pneumoniae Infection in Atherosclerosis C. pneumoniae Infection in Atherosclerosis (more detail) 33 NA Homo sapiens

Protein Lounge FEX002838 StemCell Roth05 33genes Table 3. Expression of selected genes involved in DNA repair and cell-cycle control in hTERT-transdu (more detail) 33 15741219 Homo sapiens

GeneSigDB WIG000351 Signal transduction through IL1R Interleukin-1 (IL-1) is a pro-inflammatory cytokine that signals primarily through the type 1 IL-1 r (more detail) 33 NA Homo sapiens

MSigDB MAX002602 Genes that are transcriptionally regulated by HIF1A [GeneID=3091]. Hypoxia-inducible factor 1 (HIF-1) activates transcription of genes encoding proteins that mediate a (more detail) 35 NA Homo sapiens

MSigDB TAX026307 GO:0048706 biological process embryonic skeletal system development The process, occurring during the embryonic phase, whose specific outcome is the progression of the (more detail) 35 NA Homo sapiens

GOA MOX001702 Genes associated with Computational Drug Signature isoliquiritigenin Genes associated with Computational Drug Signature isoliquiritigenin, curated by the Drug Signature (more detail) 35 25990557 Homo sapiens

DSigDB IEI009232 Protein protein interactors of human gene OCLN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OCLN (SwissProt ID=Q (more detail) 35 17535438 Homo sapiens

I2D IEI003556 Protein protein interactors of human gene DIDO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIDO1 (SwissProt ID= (more detail) 35 17535438 Homo sapiens

I2D MAX002266 Genes up regulated in BJAB cells (B lymphoma) after glutamine [PubChem=738] deprivation. RAFT1/FRAP/mTOR is a key regulator of cell growth and division and the mammalian target of rapamycin (more detail) 35 NA Homo sapiens

MSigDB WIG000056 EGF receptor (ErbB1) signaling pathway (more detail) 35 NA Homo sapiens

MSigDB MEX000203 Genes associated with Approved Drug menadione Genes associated with Approved Drug menadione, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens

DSigDB MOX003427 Genes associated with Computational Drug Signature Fenbuconazole Genes associated with Computational Drug Signature Fenbuconazole, curated by the Drug Signature Data (more detail) 35 25990557 Homo sapiens

DSigDB TAX019245 GO:0016831 molecular function carboxy lyase activity Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound. (more detail) 35 NA Homo sapiens

GOA MOX014998 Genes associated with Computational Drug Signature SB 415286 Genes associated with Computational Drug Signature SB 415286, curated by the Drug Signature Database (more detail) 35 25990557 Homo sapiens

DSigDB TAX030846 GO:0097421 biological process liver regeneration The regrowth of lost or destroyed liver. (more detail) 35 NA Homo sapiens

GOA TAX033411 GO:1904358 biological process positive regulation of telomere maintenance via telomere lengthening Any process that activates or increases the frequency, rate or extent of telomere maintenance via te (more detail) 35 NA Homo sapiens

GOA IEI008671 Protein protein interactors of human gene NDUFA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NDUFA4 (SwissProt ID (more detail) 35 17535438 Homo sapiens

I2D IEI004341 Protein protein interactors of human gene EVL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EVL (SwissProt ID=Q9 (more detail) 35 17535438 Homo sapiens

I2D MAX002920 Genes up regulated in HUVEC cells (primary endothelium) after stimulation with leukotriene LTD4 [PubChem=3908] or thrombin (F2) [GeneID=2147] for 1 h. Cysteinyl leukotrienes (cysLT), i.e., LTC4, LTD4, and LTE4, are lipid mediators derived from the 5-l (more detail) 35 NA Homo sapiens

MSigDB IEI000855 Protein protein interactors of human gene ARHGEF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARHGEF6 (SwissProt I (more detail) 35 17535438 Homo sapiens

I2D WAG000855 HIV 1 Nef: Negative effector of Fas and TNF alpha (more detail) 35 NA Homo sapiens

NCI-Nature Curated IEI003446 Protein protein interactors of human gene DEDD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DEDD (SwissProt ID=O (more detail) 35 17535438 Homo sapiens

I2D TAX019132 GO:0016620 molecular function oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts (more detail) 35 NA Homo sapiens

GOA TAX021091 GO:0031641 biological process regulation of myelination Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around (more detail) 35 NA Homo sapiens

GOA WIG000081 HIV 1 Nef: Negative effector of Fas and TNF alpha (more detail) 35 NA Homo sapiens

MSigDB IEI009715 Protein protein interactors of human gene PDS5B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDS5B (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI005909 Protein protein interactors of human gene HMGN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMGN1 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI006889 Protein protein interactors of human gene KLF10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF10 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D TAX026864 GO:0051194 biological process positive regulation of cofactor metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 24 NA Homo sapiens

GOA IEI014709 Protein protein interactors of human gene UPF3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UPF3A (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI007676 Protein protein interactors of human gene MAP4K5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP4K5 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D IEI005342 Protein protein interactors of human gene GNS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GNS (SwissProt ID=P1 (more detail) 24 17535438 Homo sapiens

I2D IEI006079 Protein protein interactors of human gene HSPB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSPB2 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI012533 Protein protein interactors of human gene SLC9A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC9A1 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D IEI002654 Protein protein interactors of human gene CLK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLK1 (SwissProt ID=P (more detail) 24 17535438 Homo sapiens

I2D MEX001196 Genes associated with Approved Drug demeclocycline hydrochloride Genes associated with Approved Drug demeclocycline hydrochloride, curated by the Drug Signature Data (more detail) 24 25990557 Homo sapiens

DSigDB WIG000311 Regulation of eIF4e and p70 S6 Kinase eIF-4F and p70 S6 kinase play critical roles in translational regulation. eIF-4F is a complex whose (more detail) 24 NA Homo sapiens

MSigDB MEX000871 Genes associated with Approved Drug dactinomycin Genes associated with Approved Drug dactinomycin, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB MOX013503 Genes associated with Computational Drug Signature lovastatin Genes associated with Computational Drug Signature lovastatin, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens

DSigDB MEX000583 Genes associated with Approved Drug idarubicin Genes associated with Approved Drug idarubicin, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens

DSigDB MOX007261 Genes associated with Computational Drug Signature beta Lapachone Genes associated with Computational Drug Signature beta-Lapachone, curated by the Drug Signature Dat (more detail) 24 25990557 Homo sapiens

DSigDB WIG000890 Genes involved in Growth hormone receptor signaling (more detail) 24 NA Homo sapiens

MSigDB TAX018959 GO:0016289 molecular function CoA hydrolase activity Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group. (more detail) 19 NA Homo sapiens

GOA IEI003362 Protein protein interactors of human gene DCP1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCP1B (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX021461 GO:0032332 biological process positive regulation of chondrocyte differentiation Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation (more detail) 19 NA Homo sapiens

GOA TAX015544 GO:0005003 molecular function ephrin receptor activity Combining with an ephrin to initiate a change in cell activity. (more detail) 19 NA Homo sapiens

GOA IEI005084 Protein protein interactors of human gene GATAD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GATAD1 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI013225 Protein protein interactors of human gene SUPT7L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SUPT7L (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI003654 Protein protein interactors of human gene DNAJB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJB2 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI014782 Protein protein interactors of human gene USP37 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP37 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI000394 Protein protein interactors of human gene AHSG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AHSG (SwissProt ID=P (more detail) 19 17535438 Homo sapiens

I2D IEI014574 Protein protein interactors of human gene UBE2F from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2F (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI005646 Protein protein interactors of human gene H2AC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AC1 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX026220 GO:0048557 biological process embryonic digestive tract morphogenesis The process in which the anatomical structures of the digestive tract are generated and organized du (more detail) 19 NA Homo sapiens

GOA IEI006758 Protein protein interactors of human gene KDM2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM2B (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI003433 Protein protein interactors of human gene DDX52 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX52 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI002673 Protein protein interactors of human gene CLPX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLPX (SwissProt ID=O (more detail) 19 17535438 Homo sapiens

I2D MOX014526 Genes associated with Computational Drug Signature Pinaflavol Genes associated with Computational Drug Signature Pinaflavol, curated by the Drug Signature Databas (more detail) 19 25990557 Homo sapiens

DSigDB MOX016711 Genes associated with Computational Drug Signature harmaline Genes associated with Computational Drug Signature harmaline, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB MOX013034 Genes associated with Computational Drug Signature HTS 05058 Genes associated with Computational Drug Signature HTS-05058, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB MOX003651 Genes associated with Computational Drug Signature alprazolam Genes associated with Computational Drug Signature alprazolam, curated by the Drug Signature Databas (more detail) 19 25990557 Homo sapiens

DSigDB WIG001696 TLR TRIF Pathway TLR-TRIF Pathway (more detail) 19 NA Homo sapiens

Protein Lounge WIG000315 EPO Signaling Pathway Erythropoietin functions to increase the number of red blood cells. Thus, it has found utility as a (more detail) 19 NA Homo sapiens

MSigDB MOX002092 Genes associated with Computational Drug Signature Manumycin A Genes associated with Computational Drug Signature Manumycin A, curated by the Drug Signature Databa (more detail) 19 25990557 Homo sapiens

DSigDB MAX001134 Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive B lineage ALL; here genes up regulated in the drug resistant samples. Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percen (more detail) 19 NA Homo sapiens

MSigDB MOX015899 Genes associated with Computational Drug Signature wortmannin Genes associated with Computational Drug Signature wortmannin, curated by the Drug Signature Databas (more detail) 19 25990557 Homo sapiens

DSigDB MOX001235 Genes associated with Computational Drug Signature FLAVANONE Genes associated with Computational Drug Signature FLAVANONE, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB FEX000053 Bone Dring04 23genes Table 2 Nuclear Genes with significant mean differences between t(4;14) and non-t(4;14) cases arrang (more detail) 19 15355895 Homo sapiens

GeneSigDB MOX003132 Genes associated with Computational Drug Signature alsterpaullone Genes associated with Computational Drug Signature alsterpaullone, curated by the Drug Signature Dat (more detail) 19 25990557 Homo sapiens

DSigDB MOX000446 Genes associated with Computational Drug Signature tetrandrine Genes associated with Computational Drug Signature tetrandrine, curated by the Drug Signature Databa (more detail) 19 25990557 Homo sapiens

DSigDB WIG002035 Estrogen signaling pathway Estrogen signaling pathway (more detail) 19 NA Homo sapiens

WikiPathway MAX000012 Genes down regulated in immunoglobulin light chain amyloidosis plasma cells (ALPC) compared to multiple myeloma (MM) cells. Immunoglobulin light chain amyloidosis (AL) is characterized by a clonal expansion of plasma cells w (more detail) 19 NA Homo sapiens

MSigDB MOX003921 Genes associated with Computational Drug Signature p,p' DDD Genes associated with Computational Drug Signature p,p'-DDD, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB TAX021792 GO:0032801 biological process receptor catabolic process The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecu (more detail) 26 NA Homo sapiens

GOA IEI000375 Protein protein interactors of human gene AGT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AGT (SwissProt ID=P0 (more detail) 26 17535438 Homo sapiens

I2D TAX029405 GO:0071353 biological process cellular response to interleukin 4 Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 26 NA Homo sapiens

GOA IEI010203 Protein protein interactors of human gene POLH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLH (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens

I2D IEI006131 Protein protein interactors of human gene IARS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IARS2 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI009020 Protein protein interactors of human gene NR1D2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR1D2 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI008727 Protein protein interactors of human gene NEFM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEFM (SwissProt ID=P (more detail) 26 17535438 Homo sapiens

I2D TAX030738 GO:0097194 biological process execution phase of apoptosis A stage of the apoptotic process that starts with the controlled breakdown of the cell through the a (more detail) 26 NA Homo sapiens

GOA IEI005564 Protein protein interactors of human gene GSTM3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GSTM3 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI011476 Protein protein interactors of human gene RORC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RORC (SwissProt ID=P (more detail) 26 17535438 Homo sapiens

I2D MOX000942 Genes associated with Computational Drug Signature Mangostin Genes associated with Computational Drug Signature Mangostin, curated by the Drug Signature Database (more detail) 26 25990557 Homo sapiens

DSigDB TAX013303 GO:0000188 biological process inactivation of MAPK activity Any process that terminates the activity of the active enzyme MAP kinase. (more detail) 26 NA Homo sapiens

GOA WAG001237 role of egf receptor transactivation by gpcrs in cardiac hypertrophy One of responses to increased blood pressure is cardiac hypertrophy through increased size of ventri (more detail) 26 NA Homo sapiens

BioCarta TAX000128 Genes annotated by the GO term GO:0006333. The formation or destruction of chromatin structures. (more detail) 26 NA Homo sapiens

MSigDB WIG000264 Regulation of BAD phosphorylation The function of the pro-apoptotic molecule BAD is regulated by phosphorylation of three sites (ser 1 (more detail) 26 NA Homo sapiens

MSigDB MOX016612 Genes associated with Computational Drug Signature COUMESTROL Genes associated with Computational Drug Signature COUMESTROL, curated by the Drug Signature Databas (more detail) 26 25990557 Homo sapiens

DSigDB TAX015592 GO:0005104 molecular function fibroblast growth factor receptor binding Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR). (more detail) 26 NA Homo sapiens

GOA TAX014419 GO:0002756 biological process MyD88 independent toll like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor not re (more detail) 26 NA Homo sapiens

GOA TAX000495 Genes annotated by the GO term GO:0043388. Any process that activates or increases the frequency, rate or extent of DNA binding, selective interaction with deoxyribonucleic acid. (more detail) 26 NA Homo sapiens

MSigDB MOX000622 Genes associated with Computational Drug Signature hesperetin Genes associated with Computational Drug Signature hesperetin, curated by the Drug Signature Databas (more detail) 26 25990557 Homo sapiens

DSigDB FEX001003 EmbryonicStemCell Xu09 26genes Table S8b.cardiac-enriched genes involved in functional categories; this table refers to genes in PP (more detail) 26 19658189 Homo sapiens

GeneSigDB MOX011949 Genes associated with Computational Drug Signature chrysin Genes associated with Computational Drug Signature chrysin, curated by the Drug Signature Database ( (more detail) 26 25990557 Homo sapiens

DSigDB MOX002742 Genes associated with Computational Drug Signature Wogonin Genes associated with Computational Drug Signature Wogonin, curated by the Drug Signature Database ( (more detail) 26 25990557 Homo sapiens

DSigDB MOX012065 Genes associated with Computational Drug Signature COUMESTROL Genes associated with Computational Drug Signature COUMESTROL, curated by the Drug Signature Databas (more detail) 26 25990557 Homo sapiens

DSigDB WAG000010 bcr signaling pathway Significant progress has been made towards delineation of the intrinsic molecular processes that reg (more detail) 26 NA Homo sapiens

BioCarta FEX001325 Leukemia Takagaki04 30genes DownRegulated Table 1b. The thirty most down-regulated genes in CCRF-CEM/10-2 cells relative to CCRFCEM cells afte (more detail) 26 15632314 Homo sapiens

GeneSigDB TAX018254 GO:0010962 biological process regulation of glucan biosynthetic process Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosyntheti (more detail) 28 NA Homo sapiens

GOA TAX035070 GO:2001171 biological process positive regulation of ATP biosynthetic process Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process. (more detail) 28 NA Homo sapiens

GOA IEI000163 Protein protein interactors of human gene ACSL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACSL3 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D TAX020135 GO:0021955 biological process central nervous system neuron axonogenesis Generation of a long process from a neuron whose cell body resides in the central nervous system. Th (more detail) 28 NA Homo sapiens

GOA WEX000109 Vitamin & Cofactor Metabolism The genes related to vitamin & cofactor metabolism (metabolism) in tumor, immune, stroma using next- (more detail) 28 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI006401 Protein protein interactors of human gene INO80 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INO80 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI011077 Protein protein interactors of human gene RBM23 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM23 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI003167 Protein protein interactors of human gene CUX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUX1 (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI000797 Protein protein interactors of human gene ARG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARG1 (SwissProt ID=P (more detail) 28 17535438 Homo sapiens

I2D IEI009868 Protein protein interactors of human gene PHLPP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHLPP1 (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D WIG000965 Genes involved in Lipoprotein metabolism (more detail) 28 NA Homo sapiens

MSigDB TAX016048 GO:0005979 biological process regulation of glycogen biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 28 NA Homo sapiens

GOA MOX017934 Genes associated with Computational Drug Signature Pemetrexed disodium Genes associated with Computational Drug Signature Pemetrexed disodium, curated by the Drug Signatur (more detail) 28 25990557 Homo sapiens

DSigDB WIG001767 LT BetaR Pathway LT-BetaR Pathway (more detail) 28 NA Homo sapiens

Protein Lounge FEX002747 Skin VanGele04 30genes Table 2b List of Classic and Variant MCC classifier genes (Variant specific genes) (more detail) 28 14755241 Homo sapiens

GeneSigDB WAG001057 IL2 signaling events mediated by STAT5 (more detail) 28 NA Homo sapiens

NCI-Nature Curated MOX004526 Genes associated with Computational Drug Signature phosphatidylcholines Genes associated with Computational Drug Signature phosphatidylcholines, curated by the Drug Signatu (more detail) 28 25990557 Homo sapiens

DSigDB WIG001603 OSM Pathway OSM Pathway (more detail) 28 NA Homo sapiens

Protein Lounge MOX004588 Genes associated with Computational Drug Signature PROPIDIUM Genes associated with Computational Drug Signature PROPIDIUM, curated by the Drug Signature Database (more detail) 28 25990557 Homo sapiens

DSigDB IEI014497 Protein protein interactors of human gene TUT4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TUT4 (SwissProt ID=Q (more detail) 30 17535438 Homo sapiens

I2D IEI006355 Protein protein interactors of human gene IL4R from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL4R (SwissProt ID=P (more detail) 30 17535438 Homo sapiens

I2D IEI014440 Protein protein interactors of human gene TTF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTF2 (SwissProt ID=Q (more detail) 30 17535438 Homo sapiens

I2D TAX025245 GO:0045736 biological process negative regulation of cyclin dependent protein serine/threonine kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent prote (more detail) 30 NA Homo sapiens

GOA IEI009074 Protein protein interactors of human gene NSD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NSD1 (SwissProt ID=Q (more detail) 30 17535438 Homo sapiens

I2D IEI000110 Protein protein interactors of human gene ACADM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACADM (SwissProt ID= (more detail) 30 17535438 Homo sapiens

I2D MOX014618 Genes associated with Computational Drug Signature prochlorperazine Genes associated with Computational Drug Signature prochlorperazine, curated by the Drug Signature D (more detail) 30 25990557 Homo sapiens

DSigDB WAG001462 signal transduction through il1r Interleukin-1 (IL-1) is a pro-inflammatory cytokine that sigls primarily through the type 1 IL-1 rec (more detail) 30 NA Homo sapiens

BioCarta MEX003714 Genes associated with Perturbagen Signature nifuroxazide Genes associated with Perturbagen Signature nifuroxazide, curated by the Drug Signature Database (DS (more detail) 30 25990557 Homo sapiens

DSigDB MOX001912 Genes associated with Computational Drug Signature 1' Acetoxychavicol acetate Genes associated with Computational Drug Signature 1'-Acetoxychavicol acetate, curated by the Drug S (more detail) 30 25990557 Homo sapiens

DSigDB TAX015275 GO:0004623 molecular function phospholipase A2 activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. (more detail) 30 NA Homo sapiens

GOA WIG000051 Ephrin B reverse signaling (more detail) 30 NA Homo sapiens

MSigDB MOX003123 Genes associated with Computational Drug Signature kenpaullone Genes associated with Computational Drug Signature kenpaullone, curated by the Drug Signature Databa (more detail) 30 25990557 Homo sapiens

DSigDB TAX000980 Genes annotated by the GO term GO:0044454. Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell. (more detail) 30 NA Homo sapiens

MSigDB TAX000538 Genes annotated by the GO term GO:0006487. The posttranslational glycosylation of protein via the N4 atom of peptidyl asparagine or the N1' atom peptidyl tryptophan. (more detail) 30 NA Homo sapiens

MSigDB TAX015886 GO:0005720 cellular component nuclear heterochromatin A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with (more detail) 30 NA Homo sapiens

GOA MOX012830 Genes associated with Computational Drug Signature genistein Genes associated with Computational Drug Signature genistein, curated by the Drug Signature Database (more detail) 30 25990557 Homo sapiens

DSigDB TAX000819 Genes annotated by the GO term GO:0019058. A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome. (more detail) 30 NA Homo sapiens

MSigDB MOX005181 Genes associated with Computational Drug Signature ( ) Epigallocatechin gallate Genes associated with Computational Drug Signature (-)-Epigallocatechin gallate, curated by the Drug (more detail) 30 25990557 Homo sapiens

DSigDB IEI002008 Protein protein interactors of human gene CCL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCL2 (SwissProt ID=P (more detail) 32 17535438 Homo sapiens

I2D IEI009838 Protein protein interactors of human gene PHF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHF1 (SwissProt ID=O (more detail) 32 17535438 Homo sapiens

I2D TAX026128 GO:0048286 biological process lung alveolus development The process whose specific outcome is the progression of the alveolus over time, from its formation (more detail) 32 NA Homo sapiens

GOA IEI012163 Protein protein interactors of human gene SH3RF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH3RF2 (SwissProt ID (more detail) 32 17535438 Homo sapiens

I2D IEI008435 Protein protein interactors of human gene MYH14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYH14 (SwissProt ID= (more detail) 32 17535438 Homo sapiens

I2D IEI008775 Protein protein interactors of human gene NF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NF1 (SwissProt ID=P2 (more detail) 32 17535438 Homo sapiens

I2D TAX029659 GO:0071772 biological process response to BMP Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 32 NA Homo sapiens

GOA TAX029660 GO:0071773 biological process cellular response to BMP stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 32 NA Homo sapiens

GOA WIG000519 Fructose and mannose metabolism (more detail) 32 NA Homo sapiens

MSigDB WIG000195 Noncanonical Wnt signaling pathway (more detail) 32 NA Homo sapiens

MSigDB MOX017806 Genes associated with Computational Drug Signature prochlorperazine Genes associated with Computational Drug Signature prochlorperazine, curated by the Drug Signature D (more detail) 32 25990557 Homo sapiens

DSigDB IEI006976 Protein protein interactors of human gene KMT2E from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KMT2E (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX027010 GO:0051444 biological process negative regulation of ubiquitin protein transferase activity Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase (more detail) 16 NA Homo sapiens

GOA TAX027068 GO:0051571 biological process positive regulation of histone H3 K4 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a (more detail) 16 NA Homo sapiens

GOA IEI010295 Protein protein interactors of human gene PPARGC1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPARGC1B (SwissProt (more detail) 16 17535438 Homo sapiens

I2D IEI003711 Protein protein interactors of human gene DNTTIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNTTIP1 (SwissProt I (more detail) 16 17535438 Homo sapiens

I2D TAX022731 GO:0035098 cellular component ESC/E(Z) complex A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Dr (more detail) 16 NA Homo sapiens

GOA IEI010823 Protein protein interactors of human gene QPCTL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene QPCTL (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI015823 Protein protein interactors of human gene ZNHIT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNHIT3 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI014995 Protein protein interactors of human gene WDR3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR3 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D TAX020254 GO:0030014 cellular component CCR4 NOT complex The evolutionarily conserved CCR4-NOT complex is involved in several aspects of mRNA metabolism, inc (more detail) 16 NA Homo sapiens

GOA TAX027013 GO:0051447 biological process negative regulation of meiotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the meiotic ce (more detail) 16 NA Homo sapiens

GOA TAX021997 GO:0033145 biological process positive regulation of intracellular steroid hormone receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the activity of any intrace (more detail) 16 NA Homo sapiens

GOA IEI007595 Protein protein interactors of human gene MAGEC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAGEC2 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI015085 Protein protein interactors of human gene WSB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WSB1 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D TAX022034 GO:0033202 cellular component DNA helicase complex A protein complex that possesses DNA helicase activity. (more detail) 16 NA Homo sapiens

GOA TAX019141 GO:0016641 molecular function oxidoreductase activity, acting on the CH NH2 group of donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or e (more detail) 16 NA Homo sapiens

GOA IEI001440 Protein protein interactors of human gene BRIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRIP1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI005701 Protein protein interactors of human gene HAND2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HAND2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI011444 Protein protein interactors of human gene RNF43 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF43 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI008935 Protein protein interactors of human gene NOL9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOL9 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D TAX020758 GO:0031011 cellular component Ino80 complex A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activi (more detail) 16 NA Homo sapiens

GOA IEI007618 Protein protein interactors of human gene MAML1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAML1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX024210 GO:0043186 cellular component P granule A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of m (more detail) 16 NA Homo sapiens

GOA TAX017849 GO:0010042 biological process response to manganese ion Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 16 NA Homo sapiens

GOA TAX029123 GO:0070822 cellular component Sin3 type complex Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core (more detail) 16 NA Homo sapiens

GOA IEI003893 Protein protein interactors of human gene E2F5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene E2F5 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D WIG000691 Genes involved in Amino acid synthesis and interconversion (transamination) (more detail) 16 NA Homo sapiens

MSigDB MAX001655 The 'cytidine analog pathway': genes involved in transport and metabolism of the anti cancer analogs of cytidine: gemcitabine and cytarabine [PubChem=596;3461;6253]. Two cytidine analogues, gemcitabine (dFdC) and 1-beta-d-arabinofuranosylcytosine (AraC), show signif (more detail) 16 NA Homo sapiens

MSigDB FEX001894 Lung Chen07 16genes Table 1. Hazard Ratios for Death from Any Cause for the 125 Patients with NSCLC and Results of Valid (more detail) 16 17202451 Homo sapiens

GeneSigDB MOX016548 Genes associated with Computational Drug Signature chondroitin Genes associated with Computational Drug Signature chondroitin, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB MOX016311 Genes associated with Computational Drug Signature METHYL METHANESULFONATE Genes associated with Computational Drug Signature METHYL METHANESULFONATE, curated by the Drug Sign (more detail) 16 25990557 Homo sapiens

DSigDB TAX001147 Genes annotated by the GO term GO:0008144. Interacting selectively with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease. (more detail) 16 NA Homo sapiens

MSigDB MOX002262 Genes associated with Computational Drug Signature Dracorhodin Genes associated with Computational Drug Signature Dracorhodin, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB MOX001423 Genes associated with Computational Drug Signature phthalic acid Genes associated with Computational Drug Signature phthalic acid, curated by the Drug Signature Data (more detail) 16 25990557 Homo sapiens

DSigDB WIG000284 Cadmium induces DNA synthesis and proliferation in macrophages Exposure to divalent cadmium ions (Cd2+) is a known cancer risk factor, but the molecular mechanisms (more detail) 16 NA Homo sapiens

MSigDB WAG000211 sprouty regulation of tyrosine kinase signals Four different members of the Sprouty protein family block the cellular proliferation and differenti (more detail) 16 NA Homo sapiens

BioCarta TAX001165 Genes annotated by the GO term GO:0008378. Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid. (more detail) 16 NA Homo sapiens

MSigDB TAX013457 GO:0000712 biological process resolution of meiotic recombination intermediates The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recom (more detail) 16 NA Homo sapiens

GOA TAX013863 GO:0001824 biological process blastocyst development The process whose specific outcome is the progression of the blastocyst over time, from its formatio (more detail) 16 NA Homo sapiens

GOA MOX006892 Genes associated with Computational Drug Signature ALDOSTERONE Genes associated with Computational Drug Signature ALDOSTERONE, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB MOX007471 Genes associated with Computational Drug Signature Canertinib dihydrochloride Genes associated with Computational Drug Signature Canertinib dihydrochloride, curated by the Drug S (more detail) 16 25990557 Homo sapiens

DSigDB MOX004802 Genes associated with Computational Drug Signature Trifluridine Genes associated with Computational Drug Signature Trifluridine, curated by the Drug Signature Datab (more detail) 16 25990557 Homo sapiens

DSigDB FEX001747 Liver Semeus08 21genes Table 4. Gene expression profiling in HepG2 cells incubated with or without etoposide (e 50 M) for (more detail) 16 18366759 Homo sapiens

GeneSigDB WAG000392 Glycosaminoglycan degradation (more detail) 16 NA Homo sapiens

KEGG WIG000078 Hypoxic and oxygen homeostasis regulation of HIF 1 alpha (more detail) 16 NA Homo sapiens

MSigDB MOX004175 Genes associated with Computational Drug Signature HARMINE Genes associated with Computational Drug Signature HARMINE, curated by the Drug Signature Database ( (more detail) 16 25990557 Homo sapiens

DSigDB TAX000183 Genes annotated by the GO term GO:0006270. The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action. (more detail) 16 NA Homo sapiens

MSigDB WIG001912 SREBF and miR33 in cholesterol and lipid homeostasis SREBF and miR33 in cholesterol and lipid homeostasis (more detail) 16 NA Homo sapiens

WikiPathway TAX001364 Genes annotated by the GO term GO:0016455. Functions to mediate the interaction of transcriptional activators with the RNA polymerase II general RNA polymerase II transcription factor complex. (more detail) 13 NA Homo sapiens

MSigDB TAX030169 GO:0080009 biological process mRNA methylation The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule. (more detail) 13 NA Homo sapiens

GOA TAX024005 GO:0042762 biological process regulation of sulfur metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 13 NA Homo sapiens

GOA TAX024199 GO:0043173 biological process nucleotide salvage Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified wi (more detail) 13 NA Homo sapiens

GOA TAX016120 GO:0006085 biological process acetyl CoA biosynthetic process The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzy (more detail) 13 NA Homo sapiens

GOA TAX016128 GO:0006098 biological process pentose phosphate shunt The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidi (more detail) 13 NA Homo sapiens

GOA PEX001814 Ets: Ets domain (more detail) 13 NA Homo sapiens

Pfam PEX001420 Pkinase C: Protein kinase C terminal domain (more detail) 13 NA Homo sapiens

Pfam MOX015215 Genes associated with Computational Drug Signature SU11652 Genes associated with Computational Drug Signature SU11652, curated by the Drug Signature Database ( (more detail) 13 25990557 Homo sapiens

DSigDB IEI003322 Protein protein interactors of human gene DBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DBP (SwissProt ID=Q1 (more detail) 13 17535438 Homo sapiens

I2D IEI005700 Protein protein interactors of human gene HAND1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HAND1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI014257 Protein protein interactors of human gene TRIM50 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM50 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI001298 Protein protein interactors of human gene BCORL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCORL1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D WIG001117 Genes involved in Purine salvage (more detail) 13 NA Homo sapiens

MSigDB WIG001363 Antimetabolite Pathway Folate Cycle, Pharmacodynamics Model non-tissue specific cancer cell displaying candidate genes which may be involved in the pharma (more detail) 13 NA Homo sapiens

PharmGKB MEX001397 Genes associated with Kinase Inhibitor AGN PC 04WTVX Genes associated with Kinase Inhibitor AGN-PC-04WTVX, curated by the Drug Signature Database (DSigDB (more detail) 13 25990557 Homo sapiens

DSigDB MEX001688 Genes associated with Kinase Inhibitor GW575808A Genes associated with Kinase Inhibitor GW575808A, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MEX001844 Genes associated with Kinase Inhibitor CHEMBL1999931 Genes associated with Kinase Inhibitor CHEMBL1999931, curated by the Drug Signature Database (DSigDB (more detail) 13 25990557 Homo sapiens

DSigDB MOX005545 Genes associated with Computational Drug Signature 1H Pyrrole 2,5 dione, 3,4 bis(4 methoxyphenyl) Genes associated with Computational Drug Signature 1H-Pyrrole-2,5-dione, 3,4-bis(4-methoxyphenyl)-, (more detail) 13 25990557 Homo sapiens

DSigDB TAX017692 GO:0009437 biological process carnitine metabolic process The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a com (more detail) 13 NA Homo sapiens

GOA TAX013567 GO:0000974 cellular component Prp19 complex A protein complex consisting of Prp19 and associated proteins that is involved in the transition fro (more detail) 13 NA Homo sapiens

GOA TAX018825 GO:0016024 biological process CDP diacylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacyl (more detail) 13 NA Homo sapiens

GOA TAX025557 GO:0046415 biological process urate metabolic process The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the (more detail) 13 NA Homo sapiens

GOA TAX020373 GO:0030205 biological process dermatan sulfate metabolic process The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans (more detail) 13 NA Homo sapiens

GOA TAX020777 GO:0031054 biological process pre miRNA processing Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule. (more detail) 13 NA Homo sapiens

GOA TAX025615 GO:0046514 biological process ceramide catabolic process The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphing (more detail) 13 NA Homo sapiens

GOA TAX020528 GO:0030497 biological process fatty acid elongation The elongation of a fatty acid chain by the sequential addition of two-carbon units. (more detail) 13 NA Homo sapiens

GOA TAX031998 GO:1901070 biological process guanosine containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (gu (more detail) 13 NA Homo sapiens

GOA IEI009089 Protein protein interactors of human gene NSRP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NSRP1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI008390 Protein protein interactors of human gene MUS81 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MUS81 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D WAG000426 calcium signaling by hbx of hepatitis b virus Hepatitis B is a small D virus that contains only 4 open reading frames in its genome. Three of the (more detail) 13 NA Homo sapiens

BioCarta TAX001076 Genes annotated by the GO term GO:0004177. Catalysis of the hydrolysis of N terminal amino acid residues from oligopeptides or polypeptides. (more detail) 13 NA Homo sapiens

MSigDB MAX001067 Genes from selected recurrently amplified regions in soft tissue tumors with supernumerary ring chromosomes. Ring chromosomes and/or giant marker chromosomes have been observed in a variety of human tumor type (more detail) 13 NA Homo sapiens

MSigDB IEI002572 Protein protein interactors of human gene CITED1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CITED1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI004199 Protein protein interactors of human gene EPC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPC2 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI011033 Protein protein interactors of human gene RASL12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RASL12 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI007842 Protein protein interactors of human gene MED13L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MED13L (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D WIG001947 Keap1 Nrf2 Pathway Keap1-Nrf2 Pathway (more detail) 13 NA Homo sapiens

WikiPathway MEX002215 Genes associated with Kinase Inhibitor resveratrol Genes associated with Kinase Inhibitor resveratrol, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MEX002041 Genes associated with Kinase Inhibitor Kinome 506 Genes associated with Kinase Inhibitor Kinome_506, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MEX001488 Genes associated with Kinase Inhibitor GSK2213727A Genes associated with Kinase Inhibitor GSK2213727A, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MEX002141 Genes associated with Kinase Inhibitor roscovitine Genes associated with Kinase Inhibitor roscovitine, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB IEI003377 Protein protein interactors of human gene DCUN1D2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCUN1D2 (SwissProt I (more detail) 13 17535438 Homo sapiens

I2D IEI010429 Protein protein interactors of human gene PRCC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRCC (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D WAG000241 telomeres telomerase cellular aging and immortality Telomeres, which define the ends of chromosomes, consist of short, tandemly repeated D sequences loo (more detail) 13 NA Homo sapiens

BioCarta TAX001153 Genes annotated by the GO term GO:0004521. Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. (more detail) 13 NA Homo sapiens

MSigDB WIG001091 Genes involved in Polymerase switching (more detail) 13 NA Homo sapiens

MSigDB TAX022454 GO:0034380 biological process high density lipoprotein particle assembly The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprote (more detail) 13 NA Homo sapiens

GOA IEI008635 Protein protein interactors of human gene NCOA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCOA4 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI010027 Protein protein interactors of human gene PLAGL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLAGL1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI013125 Protein protein interactors of human gene STK33 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STK33 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D WAG001467 nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells RXR and RAR are nuclear receptors that bind either all trans retinoic (tRA) or 9cis retinoic acid (9 (more detail) 13 NA Homo sapiens

BioCarta WAG000832 mets affect on macrophage differentiation Termil differentiation of cells is often accompanied by repression of cellular proliferation, sugges (more detail) 13 NA Homo sapiens

BioCarta TAX000730 Genes annotated by the GO term GO:0009259. The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5' hydroxyl group of its glycose moiety. (more detail) 13 NA Homo sapiens

MSigDB MEX001504 Genes associated with Kinase Inhibitor PKCbeta Inhibitor Genes associated with Kinase Inhibitor PKCbeta Inhibitor, curated by the Drug Signature Database (DS (more detail) 13 25990557 Homo sapiens

DSigDB MEX001158 Genes associated with Approved Drug cephapirin sodium Genes associated with Approved Drug cephapirin sodium, curated by the Drug Signature Database (DSigD (more detail) 13 25990557 Homo sapiens

DSigDB TAX016606 GO:0006809 biological process nitric oxide biosynthetic process The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (N (more detail) 13 NA Homo sapiens

GOA TAX023700 GO:0042159 biological process lipoprotein catabolic process The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble prot (more detail) 13 NA Homo sapiens

GOA TAX016206 GO:0006244 biological process pyrimidine nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compoun (more detail) 13 NA Homo sapiens

GOA TAX022498 GO:0034450 molecular function ubiquitin ubiquitin ligase activity Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction (more detail) 13 NA Homo sapiens

GOA TAX028976 GO:0070525 biological process tRNA threonylcarbamoyladenosine metabolic process The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside (more detail) 13 NA Homo sapiens

GOA TAX029635 GO:0071712 biological process ER associated misfolded protein catabolic process The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported fro (more detail) 13 NA Homo sapiens

GOA TAX017825 GO:0009982 molecular function pseudouridine synthase activity Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule (more detail) 13 NA Homo sapiens

GOA TAX027872 GO:0060389 biological process pathway restricted SMAD protein phosphorylation The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway rest (more detail) 13 NA Homo sapiens

GOA IEI008616 Protein protein interactors of human gene NCBP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCBP3 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX019337 GO:0017017 molecular function MAP kinase tyrosine/serine/threonine phosphatase activity Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/ (more detail) 13 NA Homo sapiens

GOA TAX024178 GO:0043138 molecular function 3' 5' DNA helicase activity Catalysis of the unwinding of the DNA helix in the direction 3' to 5'. (more detail) 13 NA Homo sapiens

GOA TAX019450 GO:0018027 biological process peptidyl lysine dimethylation The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine. (more detail) 13 NA Homo sapiens

GOA TAX021044 GO:0031543 molecular function peptidyl proline dioxygenase activity Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + s (more detail) 13 NA Homo sapiens

GOA TAX015211 GO:0004535 molecular function poly(A) specific ribonuclease activity Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP. (more detail) 13 NA Homo sapiens

GOA IEI012795 Protein protein interactors of human gene SP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SP2 (SwissProt ID=Q0 (more detail) 13 17535438 Homo sapiens

I2D FAX003056 GSEA KEGG Lung Cancer Tissue Explants (Extracellular Vesicles) RNA Degradation Top 3 KEGG pathways enriched in lung cancer tissue extract extracellular vesicle particles compared (more detail) 13 32795414 Homo sapiens

Cell WAG000018 classical complement pathway The complement system is part of the defense against invading cells and is composed of about twenty (more detail) 13 NA Homo sapiens

BioCarta MAX002148 Genes down regulated in K562 cells (bone marrow) after treatment with dasatinib [PubChem=3062316] or imatinib [PubChem=5291]. Dasatinib is an ATP-competitive, multi-targeted SRC and ABL kinase inhibitor that can bind BCR-ABL i (more detail) 13 NA Homo sapiens

MSigDB MEX002319 Genes associated with Kinase Inhibitor Kinome 491 Genes associated with Kinase Inhibitor Kinome_491, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MEX002003 Genes associated with Kinase Inhibitor Kinome 474 Genes associated with Kinase Inhibitor Kinome_474, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens

DSigDB MOX003268 Genes associated with Computational Drug Signature Dehydroxymethylepoxyquinomicin Genes associated with Computational Drug Signature Dehydroxymethylepoxyquinomicin, curated by the Dr (more detail) 13 25990557 Homo sapiens

DSigDB TAX017253 GO:0008417 molecular function fucosyltransferase activity Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate (more detail) 13 NA Homo sapiens

GOA TAX028337 GO:0061158 biological process 3' UTR mediated mRNA destabilization An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untr (more detail) 13 NA Homo sapiens

GOA TAX016385 GO:0006516 biological process glycoprotein catabolic process The chemical reactions and pathways resulting in the breakdown of glycoproteins, any protein that co (more detail) 13 NA Homo sapiens

GOA TAX016701 GO:0006957 biological process complement activation, alternative pathway Any process involved in the activation of any of the steps of the alternative pathway of the complem (more detail) 13 NA Homo sapiens

GOA TAX029756 GO:0071941 biological process nitrogen cycle metabolic process A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is (more detail) 13 NA Homo sapiens

GOA TAX029259 GO:0071025 biological process RNA surveillance The set of processes involved in identifying and degrading defective or aberrant RNAs. (more detail) 13 NA Homo sapiens

GOA TAX017147 GO:0008239 molecular function dipeptidyl peptidase activity Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain. (more detail) 13 NA Homo sapiens

GOA TAX017640 GO:0009263 biological process deoxyribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound (more detail) 13 NA Homo sapiens

GOA TAX024958 GO:0045116 biological process protein neddylation Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein. (more detail) 13 NA Homo sapiens

GOA TAX024182 GO:0043142 molecular function single stranded DNA dependent ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of singl (more detail) 13 NA Homo sapiens

GOA TAX026083 GO:0048188 cellular component Set1C/COMPASS complex A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex c (more detail) 13 NA Homo sapiens

GOA MOX014367 Genes associated with Computational Drug Signature Pazopanib Genes associated with Computational Drug Signature Pazopanib, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens

DSigDB TAX001333 Genes annotated by the GO term GO:0008276. Catalysis of the transfer of a methyl group (CH3 ) to a protein. (more detail) 13 NA Homo sapiens

MSigDB TAX000909 Genes annotated by the GO term GO:0030530. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II, that which is translated into protein) with protein, which is cell specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA. (more detail) 13 NA Homo sapiens

MSigDB WIG000496 Circadian rhythm mammal (more detail) 13 NA Homo sapiens

MSigDB WIG000624 Sulfur metabolism (more detail) 13 NA Homo sapiens

MSigDB WIG001451 Classical Complement Pathway Classical Complement Pathway (more detail) 13 NA Homo sapiens

Protein Lounge MOX004418 Genes associated with Computational Drug Signature nimodipine Genes associated with Computational Drug Signature nimodipine, curated by the Drug Signature Databas (more detail) 13 25990557 Homo sapiens

DSigDB MOX006679 Genes associated with Computational Drug Signature AGN PC 00BUNE Genes associated with Computational Drug Signature AGN-PC-00BUNE, curated by the Drug Signature Data (more detail) 13 25990557 Homo sapiens

DSigDB TAX031318 GO:0099116 biological process tRNA 5' end processing The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA. (more detail) 13 NA Homo sapiens

GOA TAX019017 GO:0016423 molecular function tRNA (guanine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA contain (more detail) 13 NA Homo sapiens

GOA TAX014841 GO:0003906 molecular function DNA (apurinic or apyrimidinic site) endonuclease activity Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a da (more detail) 13 NA Homo sapiens

GOA TAX034223 GO:1990380 molecular function Lys48 specific deubiquitinase activity Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein. (more detail) 13 NA Homo sapiens

GOA TAX032025 GO:1901160 biological process primary amino compound metabolic process The chemical reactions and pathways involving primary amino compound. (more detail) 13 NA Homo sapiens

GOA IEI014433 Protein protein interactors of human gene TTC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTC5 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D WAG001036 the igf 1 receptor and longevity A demonstrated means to increase lifespan in a wide range of organisms is through the restriction of (more detail) 13 NA Homo sapiens

BioCarta FOX000769 Genes in the cancer module 50 (more detail) 13 NA Homo sapiens

MSigDB MOX005546 Genes associated with Computational Drug Signature 1H Pyrrole 2,5 dione, 3,4 diphenyl Genes associated with Computational Drug Signature 1H-Pyrrole-2,5-dione, 3,4-diphenyl-, curated by t (more detail) 13 25990557 Homo sapiens

DSigDB TAX016459 GO:0006596 biological process polyamine biosynthetic process The chemical reactions and pathways resulting in the formation of polyamines, any organic compound c (more detail) 13 NA Homo sapiens

GOA TAX030746 GO:0097202 biological process activation of cysteine type endopeptidase activity Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase. (more detail) 13 NA Homo sapiens

GOA TAX031126 GO:0098787 biological process mRNA cleavage involved in mRNA processing Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior t (more detail) 13 NA Homo sapiens

GOA IEI011217 Protein protein interactors of human gene RFX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RFX1 (SwissProt ID=P (more detail) 21 17535438 Homo sapiens

I2D TAX025363 GO:0045943 biological process positive regulation of transcription by RNA polymerase I Any process that activates or increases the frequency, rate or extent of transcription mediated by R (more detail) 21 NA Homo sapiens

GOA TAX021870 GO:0032924 biological process activin receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to an activin rece (more detail) 21 NA Homo sapiens

GOA TAX030485 GO:0090312 biological process positive regulation of protein deacetylation Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of a (more detail) 21 NA Homo sapiens

GOA TAX022746 GO:0035145 cellular component exon exon junction complex A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. (more detail) 21 NA Homo sapiens

GOA TAX030507 GO:0090344 biological process negative regulation of cell aging Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progressi (more detail) 21 NA Homo sapiens

GOA IEI007475 Protein protein interactors of human gene LSM5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSM5 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI006297 Protein protein interactors of human gene IL13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL13 (SwissProt ID=P (more detail) 21 17535438 Homo sapiens

I2D IEI005277 Protein protein interactors of human gene GLYR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLYR1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI005918 Protein protein interactors of human gene HMOX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMOX1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI009605 Protein protein interactors of human gene PCGF5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PCGF5 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI008278 Protein protein interactors of human gene MSI2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MSI2 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI004635 Protein protein interactors of human gene FBXO2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO2 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI005995 Protein protein interactors of human gene HOXD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXD4 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D TAX031111 GO:0098751 biological process bone cell development The process whose specific outcome is the progression of a bone cell over time, from initial commitm (more detail) 21 NA Homo sapiens

GOA IEI011438 Protein protein interactors of human gene RNF34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF34 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI012037 Protein protein interactors of human gene SERPINB5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERPINB5 (SwissProt (more detail) 21 17535438 Homo sapiens

I2D WIG000444 Trefoil Factors Initiate Mucosal Healing Maintaining the integrity of the gastrointestinal tract despite the continual presence of microbial (more detail) 21 NA Homo sapiens

MSigDB GEX166666 Crohn's disease Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. (more detail) 21 18587394 Homo sapiens

GWAS Catalog MOX003378 Genes associated with Computational Drug Signature TDZD 8 Genes associated with Computational Drug Signature TDZD-8, curated by the Drug Signature Database (D (more detail) 21 25990557 Homo sapiens

DSigDB TAX001275 Genes annotated by the GO term GO:0008080. Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. (more detail) 21 NA Homo sapiens

MSigDB MOX015660 Genes associated with Computational Drug Signature TTNPB Genes associated with Computational Drug Signature TTNPB, curated by the Drug Signature Database (DS (more detail) 21 25990557 Homo sapiens

DSigDB MOX013771 Genes associated with Computational Drug Signature Molephantin Genes associated with Computational Drug Signature Molephantin, curated by the Drug Signature Databa (more detail) 21 25990557 Homo sapiens

DSigDB FEX001053 Glioblastoma Morandi08 33genes Table 2. Genes down-regulated following CPT treatment in both U87-MG and DBTRG-05; List consists of (more detail) 21 18694480 Homo sapiens

GeneSigDB MOX005110 Genes associated with Computational Drug Signature phenolphthalein Genes associated with Computational Drug Signature phenolphthalein, curated by the Drug Signature Da (more detail) 21 25990557 Homo sapiens

DSigDB MEX000391 Genes associated with Approved Drug apomorphine Genes associated with Approved Drug apomorphine, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens

DSigDB WIG001153 Genes involved in Regulatory RNA pathways (more detail) 21 NA Homo sapiens

MSigDB WAG001249 regulation of eif 4e and p70s6 kinase eIF-4F and p70 S6 kise play critical roles in translatiol regulation. eIF-4F is a complex whose func (more detail) 21 NA Homo sapiens

BioCarta MOX000235 Genes associated with Computational Drug Signature CHLOROTHALONIL Genes associated with Computational Drug Signature CHLOROTHALONIL, curated by the Drug Signature Dat (more detail) 21 25990557 Homo sapiens

DSigDB MOX006598 Genes associated with Computational Drug Signature acetate Genes associated with Computational Drug Signature acetate, curated by the Drug Signature Database ( (more detail) 21 25990557 Homo sapiens

DSigDB MEX001103 Genes associated with Approved Drug cefotaxime sodium salt Genes associated with Approved Drug cefotaxime sodium salt, curated by the Drug Signature Database ( (more detail) 21 25990557 Homo sapiens

DSigDB TAX029086 GO:0070717 molecular function poly purine tract binding Interacting selectively and non-covalently with any stretch of purines (adenine or guanine) in an RN (more detail) 23 NA Homo sapiens

GOA IEI008318 Protein protein interactors of human gene MTDH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTDH (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D IEI004274 Protein protein interactors of human gene ERLEC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERLEC1 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI012394 Protein protein interactors of human gene SLC2A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC2A1 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI011558 Protein protein interactors of human gene RPP14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPP14 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D TAX020762 GO:0031016 biological process pancreas development The process whose specific outcome is the progression of the pancreas over time, from its formation (more detail) 23 NA Homo sapiens

GOA TAX021848 GO:0032897 biological process negative regulation of viral transcription Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription. (more detail) 23 NA Homo sapiens

GOA TAX016793 GO:0007141 biological process male meiosis I A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the fir (more detail) 23 NA Homo sapiens

GOA TAX020764 GO:0031018 biological process endocrine pancreas development The process whose specific outcome is the progression of the endocrine pancreas over time, from its (more detail) 23 NA Homo sapiens

GOA TAX029302 GO:0071157 biological process negative regulation of cell cycle arrest Any process that decreases the rate, frequency, or extent of cell cycle arrest, the process in which (more detail) 23 NA Homo sapiens

GOA IEI010686 Protein protein interactors of human gene PTCH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTCH1 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D TAX018261 GO:0010971 biological process positive regulation of G2/M transition of mitotic cell cycle Any process that increases the rate or extent of progression from G2 phase to M phase of the mitotic (more detail) 23 NA Homo sapiens

GOA TAX024317 GO:0043367 biological process CD4 positive, alpha beta T cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4 (more detail) 23 NA Homo sapiens

GOA IEI004116 Protein protein interactors of human gene ELP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELP3 (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D MAX003265 Genes in cluster 1: strongly up regulated in HFW cells (fibroblast) upon treatment with sodium arsenite [PubChem=26435] at all time points. Arsenic compounds are widely distributed and arsenic ingestion is associated with many human disease (more detail) 23 NA Homo sapiens

MSigDB WAG001444 Thyroid cancer Thyroid cancer is the most common endocrine maligncy and accounts for the majority of endocrine canc (more detail) 23 NA Homo sapiens

KEGG MOX000773 Genes associated with Computational Drug Signature lonidamine Genes associated with Computational Drug Signature lonidamine, curated by the Drug Signature Databas (more detail) 23 25990557 Homo sapiens

DSigDB FOX000019 Neighborhood of CASP2 Neighborhood of CASP2 caspase 2, apoptosis-related cysteine peptidase (neural precursor cell express (more detail) 23 NA Homo sapiens

MSigDB WIG000346 Multiple antiapoptotic pathways from IGF 1R signaling lead to BAD phosphorylation IGF-1R, the type 1 receptor for insulin-like growth factor, mediates cell survival and growth in res (more detail) 23 NA Homo sapiens

MSigDB MOX004879 Genes associated with Computational Drug Signature ETYA Genes associated with Computational Drug Signature ETYA, curated by the Drug Signature Database (DSi (more detail) 23 25990557 Homo sapiens

DSigDB MOX006180 Genes associated with Computational Drug Signature 5 Amino 2 naphthalenesulfonic acid Genes associated with Computational Drug Signature 5-Amino-2-naphthalenesulfonic acid, curated by th (more detail) 23 25990557 Homo sapiens

DSigDB MOX017284 Genes associated with Computational Drug Signature Flavopiridol hydrochloride Genes associated with Computational Drug Signature Flavopiridol hydrochloride, curated by the Drug S (more detail) 23 25990557 Homo sapiens

DSigDB MOX015610 Genes associated with Computational Drug Signature triamterene Genes associated with Computational Drug Signature triamterene, curated by the Drug Signature Databa (more detail) 23 25990557 Homo sapiens

DSigDB MOX003692 Genes associated with Computational Drug Signature apomorphine Genes associated with Computational Drug Signature apomorphine, curated by the Drug Signature Databa (more detail) 23 25990557 Homo sapiens

DSigDB TAX000274 Genes annotated by the GO term GO:0008629. Any process induced by intracellular signals that directly activates any of the steps required for cell death by apoptosis. (more detail) 23 NA Homo sapiens

MSigDB TAX030664 GO:0097066 biological process response to thyroid hormone A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme prod (more detail) 25 NA Homo sapiens

GOA TAX031807 GO:1900101 biological process regulation of endoplasmic reticulum unfolded protein response Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein r (more detail) 25 NA Homo sapiens

GOA IEI000517 Protein protein interactors of human gene ALPP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ALPP (SwissProt ID=P (more detail) 25 17535438 Homo sapiens

I2D IEI012258 Protein protein interactors of human gene SKIV2L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SKIV2L (SwissProt ID (more detail) 25 17535438 Homo sapiens

I2D TAX032838 GO:1903205 biological process regulation of hydrogen peroxide induced cell death Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced cell death. (more detail) 25 NA Homo sapiens

GOA IEI008036 Protein protein interactors of human gene MLLT6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MLLT6 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D TAX032937 GO:1903409 biological process reactive oxygen species biosynthetic process The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molec (more detail) 25 NA Homo sapiens

GOA TAX027828 GO:0060334 biological process regulation of interferon gamma mediated signaling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated (more detail) 25 NA Homo sapiens

GOA TAX027824 GO:0060330 biological process regulation of response to interferon gamma Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response (more detail) 25 NA Homo sapiens

GOA TAX026273 GO:0048665 biological process neuron fate specification The process in which a cell becomes capable of differentiating autonomously into a neuron in an envi (more detail) 25 NA Homo sapiens

GOA MOX016667 Genes associated with Computational Drug Signature DEMECLOCYCLINE HYDROCHLORIDE Genes associated with Computational Drug Signature DEMECLOCYCLINE HYDROCHLORIDE, curated by the Drug (more detail) 25 25990557 Homo sapiens

DSigDB MOX017960 Genes associated with Computational Drug Signature PYRIDOXINE HYDROCHLORIDE Genes associated with Computational Drug Signature PYRIDOXINE HYDROCHLORIDE, curated by the Drug Sig (more detail) 25 25990557 Homo sapiens

DSigDB MOX004290 Genes associated with Computational Drug Signature mebendazole Genes associated with Computational Drug Signature mebendazole, curated by the Drug Signature Databa (more detail) 25 25990557 Homo sapiens

DSigDB MOX003276 Genes associated with Computational Drug Signature Pomalidomide Genes associated with Computational Drug Signature Pomalidomide, curated by the Drug Signature Datab (more detail) 25 25990557 Homo sapiens

DSigDB MOX003091 Genes associated with Computational Drug Signature Lonafarnib Genes associated with Computational Drug Signature Lonafarnib, curated by the Drug Signature Databas (more detail) 25 25990557 Homo sapiens

DSigDB MOX004398 Genes associated with Computational Drug Signature naloxone Genes associated with Computational Drug Signature naloxone, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB MOX003919 Genes associated with Computational Drug Signature dapsone Genes associated with Computational Drug Signature dapsone, curated by the Drug Signature Database ( (more detail) 25 25990557 Homo sapiens

DSigDB FEX003369 Viral Sun01 27genes Apoptosis Related TABLE 2. Expression Profile of Apoptosis-Related Genes in BC-2 Cells and Its Effect by MAP30 (more detail) 25 11573962 Homo sapiens

GeneSigDB WAG000650 bioactive peptide induced signaling pathway Many different peptides act as sigling molecules, including the proinflammatory peptide bradykinin, (more detail) 25 NA Homo sapiens

BioCarta MOX018088 Genes associated with Computational Drug Signature Vemurafenib Genes associated with Computational Drug Signature Vemurafenib, curated by the Drug Signature Databa (more detail) 25 25990557 Homo sapiens

DSigDB MOX014719 Genes associated with Computational Drug Signature QUINACRINE DIHYDROCHLORIDE Genes associated with Computational Drug Signature QUINACRINE DIHYDROCHLORIDE, curated by the Drug S (more detail) 25 25990557 Homo sapiens

DSigDB MOX013248 Genes associated with Computational Drug Signature juglone Genes associated with Computational Drug Signature juglone, curated by the Drug Signature Database ( (more detail) 25 25990557 Homo sapiens

DSigDB MOX004652 Genes associated with Computational Drug Signature CARBARYL Genes associated with Computational Drug Signature CARBARYL, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB MOX000869 Genes associated with Computational Drug Signature ALLETHRIN Genes associated with Computational Drug Signature ALLETHRIN, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB WIG001922 IL 7 signaling pathway IL-7 signaling pathway (more detail) 25 NA Homo sapiens

WikiPathway IEI015194 Protein protein interactors of human gene ZBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBP1 (SwissProt ID=Q (more detail) 18 17535438 Homo sapiens

I2D TAX024574 GO:0044030 biological process regulation of DNA methylation Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group (more detail) 18 NA Homo sapiens

GOA TAX020992 GO:0031435 molecular function mitogen activated protein kinase kinase kinase binding Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, an (more detail) 18 NA Homo sapiens

GOA IEI015704 Protein protein interactors of human gene ZNF687 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF687 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI015212 Protein protein interactors of human gene ZBTB33 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB33 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI001067 Protein protein interactors of human gene ATP1B3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP1B3 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI006433 Protein protein interactors of human gene INTS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS2 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI009752 Protein protein interactors of human gene PER2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PER2 (SwissProt ID=O (more detail) 18 17535438 Homo sapiens

I2D IEI011634 Protein protein interactors of human gene RRM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRM2 (SwissProt ID=P (more detail) 18 17535438 Homo sapiens

I2D IEI008783 Protein protein interactors of human gene NFATC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFATC3 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI001071 Protein protein interactors of human gene ATP2A3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP2A3 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI009110 Protein protein interactors of human gene NTHL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NTHL1 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D TAX026314 GO:0048714 biological process positive regulation of oligodendrocyte differentiation Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentia (more detail) 18 NA Homo sapiens

GOA IEI009718 Protein protein interactors of human gene PDX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDX1 (SwissProt ID=P (more detail) 18 17535438 Homo sapiens

I2D IEI010239 Protein protein interactors of human gene POLR3H from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR3H (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI007150 Protein protein interactors of human gene LARP4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LARP4B (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI014672 Protein protein interactors of human gene UHMK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UHMK1 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI012765 Protein protein interactors of human gene SORL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SORL1 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D TAX021317 GO:0032069 biological process regulation of nuclease activity Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of est (more detail) 18 NA Homo sapiens

GOA IEI009145 Protein protein interactors of human gene NUDT16L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUDT16L1 (SwissProt (more detail) 18 17535438 Homo sapiens

I2D IEI015538 Protein protein interactors of human gene ZNF423 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF423 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI008944 Protein protein interactors of human gene NOP16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOP16 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D MOX000029 Genes associated with Computational Drug Signature Harmol Genes associated with Computational Drug Signature Harmol, curated by the Drug Signature Database (D (more detail) 18 25990557 Homo sapiens

DSigDB MOX003450 Genes associated with Computational Drug Signature 5 Nitroso 8 quinolinol Genes associated with Computational Drug Signature 5-Nitroso-8-quinolinol, curated by the Drug Signa (more detail) 18 25990557 Homo sapiens

DSigDB TAX014634 GO:0003203 biological process endocardial cushion morphogenesis The process in which the anatomical structure of the endocardial cushion is generated and organized. (more detail) 18 NA Homo sapiens

GOA MOX003248 Genes associated with Computational Drug Signature alvespimycin Genes associated with Computational Drug Signature alvespimycin, curated by the Drug Signature Datab (more detail) 18 25990557 Homo sapiens

DSigDB TAX001315 Genes annotated by the GO term GO:0016776. Catalysis of the transfer of a phosphorus containing group from one compound (donor) to a phosphate group (acceptor). (more detail) 18 NA Homo sapiens

MSigDB MOX000121 Genes associated with Computational Drug Signature Tylophorine Genes associated with Computational Drug Signature Tylophorine, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens

DSigDB TAX000030 Genes annotated by the GO term GO:0006040. The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group. (more detail) 18 NA Homo sapiens

MSigDB TAX013220 GO:0000028 biological process ribosomal small subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small (more detail) 18 NA Homo sapiens

GOA MOX006461 Genes associated with Computational Drug Signature A 443654 Genes associated with Computational Drug Signature A-443654, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB FEX000107 BoneMarrow Abraham05 20genes Table 5. Genes with significantly lower average gene expression in AL plasma cells than in MM cells (more detail) 18 15388584 Homo sapiens

GeneSigDB WIG000853 Genes involved in G1/S Specific Transcription (more detail) 18 NA Homo sapiens

MSigDB WAG000236 cdk regulation of dna replication Initiation of D replication in eukaryotes is a highly conserved, multi-step process (replication lic (more detail) 18 NA Homo sapiens

BioCarta WIG000374 CDK Regulation of DNA Replication Initiation of DNA replication in eukaryotes is a highly conserved, multi-step process (replication l (more detail) 18 NA Homo sapiens

MSigDB MOX015249 Genes associated with Computational Drug Signature suramin Genes associated with Computational Drug Signature suramin, curated by the Drug Signature Database ( (more detail) 18 25990557 Homo sapiens

DSigDB IEI001836 Protein protein interactors of human gene CAT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAT (SwissProt ID=P0 (more detail) 27 17535438 Homo sapiens

I2D IEI006354 Protein protein interactors of human gene IL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL4 (SwissProt ID=P0 (more detail) 27 17535438 Homo sapiens

I2D IEI005770 Protein protein interactors of human gene HEATR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HEATR1 (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D IEI008792 Protein protein interactors of human gene NFIC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFIC (SwissProt ID=P (more detail) 27 17535438 Homo sapiens

I2D TAX034438 GO:2000036 biological process regulation of stem cell population maintenance Any process that modulates the frequency, rate or extent of stem cell population maintenance. (more detail) 27 NA Homo sapiens

GOA TAX017980 GO:0010575 biological process positive regulation of vascular endothelial growth factor production Any process that increases or activates the frequency, rate, or extent of production of vascular end (more detail) 27 NA Homo sapiens

GOA TAX034739 GO:2000515 biological process negative regulation of CD4 positive, alpha beta T cell activation Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-bet (more detail) 27 NA Homo sapiens

GOA IEI006115 Protein protein interactors of human gene HUS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HUS1 (SwissProt ID=O (more detail) 27 17535438 Homo sapiens

I2D IEI004659 Protein protein interactors of human gene FBXO7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO7 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI007796 Protein protein interactors of human gene MCM3AP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCM3AP (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D IEI000244 Protein protein interactors of human gene ADAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ADAP1 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI010317 Protein protein interactors of human gene PPIL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPIL1 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI006153 Protein protein interactors of human gene IDH3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IDH3A (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D IEI007450 Protein protein interactors of human gene LRRFIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRRFIP1 (SwissProt I (more detail) 27 17535438 Homo sapiens

I2D IEI009815 Protein protein interactors of human gene PGM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PGM1 (SwissProt ID=P (more detail) 27 17535438 Homo sapiens

I2D IEI005256 Protein protein interactors of human gene GLO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLO1 (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D TAX027832 GO:0060338 biological process regulation of type I interferon mediated signaling pathway Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling p (more detail) 27 NA Homo sapiens

GOA IEI009277 Protein protein interactors of human gene OPA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OPA1 (SwissProt ID=O (more detail) 27 17535438 Homo sapiens

I2D MOX000346 Genes associated with Computational Drug Signature formononetin Genes associated with Computational Drug Signature formononetin, curated by the Drug Signature Datab (more detail) 27 25990557 Homo sapiens

DSigDB TAX000382 Genes annotated by the GO term GO:0045596. Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation. (more detail) 27 NA Homo sapiens

MSigDB FOX000556 Genes in the cancer module 226 (more detail) 27 NA Homo sapiens

MSigDB FEX000424 Breast Rahman06 39genes Table 1. Fold changes of specific genes in MDA-MB-231 cells treated with 3 3?-diindolylmethane (more detail) 27 16651453 Homo sapiens

GeneSigDB MOX002357 Genes associated with Computational Drug Signature bisindolylmaleimide IX Genes associated with Computational Drug Signature bisindolylmaleimide IX, curated by the Drug Signa (more detail) 27 25990557 Homo sapiens

DSigDB MOX002462 Genes associated with Computational Drug Signature Norcantharidin Genes associated with Computational Drug Signature Norcantharidin, curated by the Drug Signature Dat (more detail) 27 25990557 Homo sapiens

DSigDB FOX000532 Genes in the cancer module 200 (more detail) 27 NA Homo sapiens

MSigDB TAX000710 Genes annotated by the GO term GO:0001666. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. (more detail) 27 NA Homo sapiens

MSigDB FEX001853 Lung Ju05 40genes Table 3 Differentially expressed genes related to WNT pathways apoptosis or cell proliferation-ide (more detail) 27 16049682 Homo sapiens

GeneSigDB MOX004762 Genes associated with Computational Drug Signature DL Thyroxine Genes associated with Computational Drug Signature DL-Thyroxine, curated by the Drug Signature Datab (more detail) 27 25990557 Homo sapiens

DSigDB MOX002991 Genes associated with Computational Drug Signature roscovitine Genes associated with Computational Drug Signature roscovitine, curated by the Drug Signature Databa (more detail) 27 25990557 Homo sapiens

DSigDB MOX000814 Genes associated with Computational Drug Signature Benzo(a)pyrene 7,8 dihydrodiol Genes associated with Computational Drug Signature Benzo(a)pyrene 7,8-dihydrodiol, curated by the Dr (more detail) 27 25990557 Homo sapiens

DSigDB MOX004636 Genes associated with Computational Drug Signature Ademetionine Genes associated with Computational Drug Signature Ademetionine, curated by the Drug Signature Datab (more detail) 27 25990557 Homo sapiens

DSigDB IEI013343 Protein protein interactors of human gene TAF1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF1B (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI008358 Protein protein interactors of human gene MTPN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTPN (SwissProt ID=P (more detail) 29 17535438 Homo sapiens

I2D TAX026067 GO:0048147 biological process negative regulation of fibroblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or repr (more detail) 29 NA Homo sapiens

GOA TAX025514 GO:0046320 biological process regulation of fatty acid oxidation Any process that modulates the frequency, rate or extent of fatty acid oxidation. (more detail) 29 NA Homo sapiens

GOA IEI000859 Protein protein interactors of human gene ARID1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARID1B (SwissProt ID (more detail) 29 17535438 Homo sapiens

I2D TAX026739 GO:0051019 molecular function mitogen activated protein kinase binding Interacting selectively and non-covalently with a mitogen-activated protein kinase. (more detail) 29 NA Homo sapiens

GOA TAX024397 GO:0043500 biological process muscle adaptation A process in which muscle adapts, with consequent modifications to structural and/or functional phen (more detail) 29 NA Homo sapiens

GOA IEI007811 Protein protein interactors of human gene MCTS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCTS1 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D IEI004008 Protein protein interactors of human gene EHD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EHD4 (SwissProt ID=Q (more detail) 29 17535438 Homo sapiens

I2D IEI009031 Protein protein interactors of human gene NR2F1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR2F1 (SwissProt ID= (more detail) 29 17535438 Homo sapiens

I2D MOX018062 Genes associated with Computational Drug Signature pyridoxal phosphate Genes associated with Computational Drug Signature pyridoxal phosphate, curated by the Drug Signatur (more detail) 29 25990557 Homo sapiens

DSigDB WIG001530 Granzyme Pathway Granzyme Pathway (more detail) 29 NA Homo sapiens

Protein Lounge FEX003498 Viral Cairo08 76genes Table S9a. Overrepresented GO Terms among Genes Differently Expressed between rC2 and rC1 HB Subclas (more detail) 29 19061838 Homo sapiens

GeneSigDB MEX000457 Genes associated with Approved Drug 5 azacytidine Genes associated with Approved Drug 5-azacytidine, curated by the Drug Signature Database (DSigDB). (more detail) 29 25990557 Homo sapiens

DSigDB FOX000175 Neighborhood of MSH6 Neighborhood of MSH6 mutS homolog 6 (E. coli) in the GNF2 expression compendium (more detail) 29 NA Homo sapiens

MSigDB FEX001672 Leukemia Chiaretti10 38genes Supplemental Table1b: Differentially expressed genes between high in HOXA patients (more detail) 29 20418243 Homo sapiens

GeneSigDB FOX000103 Neighborhood of CBFB Neighborhood of CBFB core-binding factor, beta subunit in the GNF2 expression compendium (more detail) 29 NA Homo sapiens

MSigDB FEX001907 Lung Johnson07 46genes Table 1. Cell cycle cell division and cell proliferation genes that respond to excess let-7 (more detail) 29 17699775 Homo sapiens

GeneSigDB MOX004857 Genes associated with Computational Drug Signature ZIRAM Genes associated with Computational Drug Signature ZIRAM, curated by the Drug Signature Database (DS (more detail) 29 25990557 Homo sapiens

DSigDB WIG001517 GADD45 Pathway GADD45 Pathway (more detail) 29 NA Homo sapiens

Protein Lounge MOX003507 Genes associated with Computational Drug Signature PI 103 Genes associated with Computational Drug Signature PI-103, curated by the Drug Signature Database (D (more detail) 29 25990557 Homo sapiens

DSigDB IEI008521 Protein protein interactors of human gene NAA15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NAA15 (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D TAX021106 GO:0031663 biological process lipopolysaccharide mediated signaling pathway A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor o (more detail) 31 NA Homo sapiens

GOA TAX032406 GO:1902186 biological process regulation of viral release from host cell Any process that modulates the frequency, rate or extent of viral release from host cell. (more detail) 31 NA Homo sapiens

GOA TAX018042 GO:0010665 biological process regulation of cardiac muscle cell apoptotic process Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programme (more detail) 31 NA Homo sapiens

GOA TAX024411 GO:0043516 biological process regulation of DNA damage response, signal transduction by p53 class mediator Any process that modulates the frequency, rate or extent of the cascade of processes induced by the (more detail) 31 NA Homo sapiens

GOA TAX032314 GO:1901976 biological process regulation of cell cycle checkpoint Any process that modulates the frequency, rate or extent of cell cycle checkpoint. (more detail) 31 NA Homo sapiens

GOA TAX025673 GO:0046627 biological process negative regulation of insulin receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signa (more detail) 31 NA Homo sapiens

GOA IEI014438 Protein protein interactors of human gene TTC9C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTC9C (SwissProt ID= (more detail) 31 17535438 Homo sapiens

I2D IEI007703 Protein protein interactors of human gene MAPKAPK5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAPKAPK5 (SwissProt (more detail) 31 17535438 Homo sapiens

I2D IEI012032 Protein protein interactors of human gene SERPINB12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERPINB12 (SwissProt (more detail) 31 17535438 Homo sapiens

I2D TAX016787 GO:0007127 biological process meiosis I The first meiotic nuclear division in which homologous chromosomes are paired and segregated from ea (more detail) 31 NA Homo sapiens

GOA TAX017846 GO:0010039 biological process response to iron ion Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 31 NA Homo sapiens

GOA TAX027306 GO:0051985 biological process negative regulation of chromosome segregation Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation (more detail) 31 NA Homo sapiens

GOA IEI013077 Protein protein interactors of human gene STAMBPL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAMBPL1 (SwissProt (more detail) 31 17535438 Homo sapiens

I2D TAX019011 GO:0016417 molecular function S acyltransferase activity Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule. (more detail) 31 NA Homo sapiens

GOA MOX017109 Genes associated with Computational Drug Signature captopril Genes associated with Computational Drug Signature captopril, curated by the Drug Signature Database (more detail) 31 25990557 Homo sapiens

DSigDB MOX003675 Genes associated with Computational Drug Signature AMPHETAMINE Genes associated with Computational Drug Signature AMPHETAMINE, curated by the Drug Signature Databa (more detail) 31 25990557 Homo sapiens

DSigDB IEI010551 Protein protein interactors of human gene PRPSAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRPSAP2 (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D IEI004198 Protein protein interactors of human gene EPC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPC1 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI008017 Protein protein interactors of human gene MKNK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MKNK2 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI004558 Protein protein interactors of human gene FAM98B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM98B (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI010204 Protein protein interactors of human gene POLI from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLI (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI009834 Protein protein interactors of human gene PHC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHC3 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI013320 Protein protein interactors of human gene TAB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAB3 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI005962 Protein protein interactors of human gene HOXA10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXA10 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI002205 Protein protein interactors of human gene CDCA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDCA5 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI002490 Protein protein interactors of human gene CHMP2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHMP2B (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI014610 Protein protein interactors of human gene UBL5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBL5 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI006402 Protein protein interactors of human gene INO80B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INO80B (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI009445 Protein protein interactors of human gene PAG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAG1 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI002274 Protein protein interactors of human gene CDKN2AIP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDKN2AIP (SwissProt (more detail) 20 17535438 Homo sapiens

I2D IEI001091 Protein protein interactors of human gene ATP5ME from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP5ME (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI004397 Protein protein interactors of human gene F7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene F7 (SwissProt ID=P08 (more detail) 20 17535438 Homo sapiens

I2D IEI003686 Protein protein interactors of human gene DNAJC8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJC8 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI002559 Protein protein interactors of human gene CILK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CILK1 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX015873 GO:0005685 cellular component U1 snRNP A ribonucleoprotein complex that contains small nuclear RNA U1. (more detail) 20 NA Homo sapiens

GOA MEX002625 Genes associated with Perturbagen Signature AR A014418 Genes associated with Perturbagen Signature AR-A014418, curated by the Drug Signature Database (DSig (more detail) 20 25990557 Homo sapiens

DSigDB WIG001563 IL 9 Pathway IL-9 Pathway (more detail) 20 NA Homo sapiens

Protein Lounge TAX001025 Genes annotated by the GO term GO:0033279. Either of the two ribonucleoprotein complexes that associate to form a ribosome. (more detail) 20 NA Homo sapiens

MSigDB MAX001734 Genes up regulated in HCT116 cells (colon cancer) after treatment with amifostine [PubChem=2141] depending on the presence of TP53 [GeneID=7157]: TP53 positive vs TP53 null cells. The aminothiol WR1065 exerts selective cytoprotective effects in normal cells compared to cancer cel (more detail) 20 NA Homo sapiens

MSigDB MOX006583 Genes associated with Computational Drug Signature acacetin Genes associated with Computational Drug Signature acacetin, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB TAX013913 GO:0001892 biological process embryonic placenta development The embryonically driven process whose specific outcome is the progression of the placenta over time (more detail) 20 NA Homo sapiens

GOA MOX012480 Genes associated with Computational Drug Signature edaravone Genes associated with Computational Drug Signature edaravone, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB MOX001747 Genes associated with Computational Drug Signature Nimbolide Genes associated with Computational Drug Signature Nimbolide, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB WIG001749 MNAR/PELP1 and Estrogen Receptor Interaction MNAR/PELP1 and Estrogen Receptor Interaction (more detail) 20 NA Homo sapiens

Protein Lounge MOX003219 Genes associated with Computational Drug Signature Pyridaben Genes associated with Computational Drug Signature Pyridaben, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB MOX001014 Genes associated with Computational Drug Signature acacetin Genes associated with Computational Drug Signature acacetin, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB FEX001372 Leukemia Gebauer05 20genes PHCCells Table 2b.Table showing the 20 most strongly expressed genes in PHC. The genes were ranked by the mea (more detail) 20 15950496 Homo sapiens

GeneSigDB WAG000012 cell cycle: g2/m checkpoint The G2/M D damage checkpoint prevents the cell from entering mitosis (M phase) if the genome is dama (more detail) 20 NA Homo sapiens

BioCarta WAG001006 tpo signaling pathway Thrombopoietin (TPO) binds to its receptor inducing aggregation and activation. TPO sigls its growth (more detail) 20 NA Homo sapiens

BioCarta TAX013660 GO:0001502 biological process cartilage condensation The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes. (more detail) 20 NA Homo sapiens

GOA FEX000249 Breast Bertucci02 23genes Figure 2A. Molecular Classification of poor-prognosis breast tumors; a 23-gene set (more detail) 20 12538167 Homo sapiens

GeneSigDB MOX012423 Genes associated with Computational Drug Signature Doramapimod Genes associated with Computational Drug Signature Doramapimod, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB FEX002383 Mouth Ruutu04 15genes Table V. Genes which increased expression (two-fold or more) detected in both UT-SCC cell lines (UT- (more detail) 15 15517866 Homo sapiens

GeneSigDB IEI006439 Protein protein interactors of human gene INTS7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS7 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D TAX028783 GO:0070182 molecular function DNA polymerase binding Interacting selectively and non-covalently with a DNA polymerase. (more detail) 15 NA Homo sapiens

GOA IEI015240 Protein protein interactors of human gene ZC3H12A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZC3H12A (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D IEI005247 Protein protein interactors of human gene GLI2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLI2 (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D IEI012954 Protein protein interactors of human gene SRBD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRBD1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D WIG000532 Glycosphingolipid biosynthesis ganglio series (more detail) 15 NA Homo sapiens

MSigDB TAX024031 GO:0042809 molecular function vitamin D receptor binding Interacting selectively and non-covalently with the vitamin D receptor, a nuclear receptor that medi (more detail) 15 NA Homo sapiens

GOA MAX002681 Selected electrophile and drug detoxication genes down regulated in A549 and H460 cells (lung cancer) upon knockdown of NFE2L2 [GeneID=4780] by RNAi. Nuclear factor erythroid-2-related factor 2 (Nrf2) is a redox-sensitive transcription factor that re (more detail) 15 NA Homo sapiens

MSigDB MOX000069 Genes associated with Computational Drug Signature Cinobufagin Genes associated with Computational Drug Signature Cinobufagin, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB TAX020400 GO:0030238 biological process male sex determination The specification of male sex of an individual organism. (more detail) 15 NA Homo sapiens

GOA IEI011434 Protein protein interactors of human gene RNF25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF25 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI005282 Protein protein interactors of human gene GMEB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GMEB1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI005978 Protein protein interactors of human gene HOXB7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXB7 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI000096 Protein protein interactors of human gene ABRAXAS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABRAXAS1 (SwissProt (more detail) 15 17535438 Homo sapiens

I2D FEX001587 Leukemia Sanchez Guijo08 15genes SuppTable2m Genes related to the ubiquitination process (more detail) 15 18722011 Homo sapiens

GeneSigDB MAX001755 Non histone proteins that are acetylated. The path to the discovery of suberoylanilide hydroxamic acid (SAHA, vorinostat) began over three dec (more detail) 15 NA Homo sapiens

MSigDB WIG001050 Genes involved in Oxygen dependent Proline Hydroxylation of Hypoxia inducible Factor Alpha (more detail) 15 NA Homo sapiens

MSigDB TAX017788 GO:0009881 molecular function photoreceptor activity The function of absorbing and responding to incidental electromagnetic radiation, particularly visib (more detail) 15 NA Homo sapiens

GOA TAX018786 GO:0015923 molecular function mannosidase activity Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cycl (more detail) 15 NA Homo sapiens

GOA TAX015862 GO:0005671 cellular component Ada2/Gcn5/Ada3 transcription activator complex A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of tra (more detail) 15 NA Homo sapiens

GOA IEI010241 Protein protein interactors of human gene POLRMT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLRMT (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI003567 Protein protein interactors of human gene DIRAS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIRAS3 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI012870 Protein protein interactors of human gene SPHK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPHK1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI014813 Protein protein interactors of human gene UTP15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UTP15 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI000993 Protein protein interactors of human gene ASPM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASPM (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D MOX012826 Genes associated with Computational Drug Signature gemfibrozil Genes associated with Computational Drug Signature gemfibrozil, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB MOX012985 Genes associated with Computational Drug Signature HARMINE Genes associated with Computational Drug Signature HARMINE, curated by the Drug Signature Database ( (more detail) 15 25990557 Homo sapiens

DSigDB TAX027570 GO:0055089 biological process fatty acid homeostasis Any process involved in the maintenance of an internal steady state of fatty acid within an organism (more detail) 15 NA Homo sapiens

GOA IEI003519 Protein protein interactors of human gene DHFR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHFR (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D TAX023285 GO:0036149 biological process phosphatidylinositol acyl chain remodeling Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation (more detail) 15 NA Homo sapiens

GOA TAX034441 GO:2000042 biological process negative regulation of double strand break repair via homologous recombination Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break re (more detail) 15 NA Homo sapiens

GOA IEI004854 Protein protein interactors of human gene FOSB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOSB (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D IEI004986 Protein protein interactors of human gene GAA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GAA (SwissProt ID=P1 (more detail) 15 17535438 Homo sapiens

I2D IEI001462 Protein protein interactors of human gene BTBD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BTBD1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D FEX001389 Leukemia Chiaretti05 16genes Table 4. Kinase genes with high-level gene expression in samples without known molecular rearrangeme (more detail) 15 16243790 Homo sapiens

GeneSigDB WIG001034 Genes involved in NRIF signals cell death from the nucleus (more detail) 15 NA Homo sapiens

MSigDB WIG001225 Genes involved in Signalling to p38 via RIT and RIN (more detail) 15 NA Homo sapiens

MSigDB WAG000601 Parkinson's disease Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal n (more detail) 15 NA Homo sapiens

KEGG TAX013242 GO:0000076 biological process DNA replication checkpoint A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is co (more detail) 15 NA Homo sapiens

GOA TAX001169 Genes annotated by the GO term GO:0004364. Catalysis of the reaction: R X + glutathione = H X + R S glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. (more detail) 15 NA Homo sapiens

MSigDB MOX000574 Genes associated with Computational Drug Signature MELAMINE Genes associated with Computational Drug Signature MELAMINE, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX002767 Genes associated with Computational Drug Signature tazarotene Genes associated with Computational Drug Signature tazarotene, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens

DSigDB TAX021899 GO:0032968 biological process positive regulation of transcription elongation from RNA polymerase II promoter Any process that activates or increases the frequency, rate or extent of transcription elongation, t (more detail) 15 NA Homo sapiens

GOA TAX032842 GO:1903209 biological process positive regulation of oxidative stress induced cell death Any process that activates or increases the frequency, rate or extent of oxidative stress-induced ce (more detail) 15 NA Homo sapiens

GOA MOX014862 Genes associated with Computational Drug Signature Rocaglamide Genes associated with Computational Drug Signature Rocaglamide, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB IEI008971 Protein protein interactors of human gene NPAT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NPAT (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI010276 Protein protein interactors of human gene POU2AF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POU2AF1 (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D IEI013079 Protein protein interactors of human gene STAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAP2 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI012616 Protein protein interactors of human gene SMG6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMG6 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D TAX025593 GO:0046479 biological process glycosphingolipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with (more detail) 12 NA Homo sapiens

GOA IEI015099 Protein protein interactors of human gene XAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XAF1 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI002829 Protein protein interactors of human gene COMMD10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD10 (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI009844 Protein protein interactors of human gene PHF19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHF19 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI006837 Protein protein interactors of human gene KIF26B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIF26B (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D TAX022775 GO:0035246 biological process peptidyl arginine N methylation The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein. (more detail) 12 NA Homo sapiens

GOA TAX016866 GO:0007252 biological process I kappaB phosphorylation The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosph (more detail) 12 NA Homo sapiens

GOA TAX017498 GO:0009086 biological process methionine biosynthetic process The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio) (more detail) 12 NA Homo sapiens

GOA TAX019493 GO:0018206 biological process peptidyl methionine modification The modification of peptidyl-methionine. (more detail) 12 NA Homo sapiens

GOA TAX027189 GO:0051787 molecular function misfolded protein binding Interacting selectively and non-covalently with a misfolded protein. (more detail) 12 NA Homo sapiens

GOA TAX021302 GO:0032042 biological process mitochondrial DNA metabolic process The chemical reactions and pathways involving mitochondrial DNA. (more detail) 12 NA Homo sapiens

GOA TAX017338 GO:0008540 cellular component proteasome regulatory particle, base subcomplex The subcomplex of the proteasome regulatory particle that directly associates with the proteasome co (more detail) 12 NA Homo sapiens

GOA TAX019285 GO:0016889 molecular function endodeoxyribonuclease activity, producing 3' phosphomonoesters Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal bre (more detail) 12 NA Homo sapiens

GOA TAX020617 GO:0030677 cellular component ribonuclease P complex A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-t (more detail) 12 NA Homo sapiens

GOA TAX017394 GO:0008655 biological process pyrimidine containing compound salvage Any process that generates a pyrimidine-containing compound, any nucleobase, nucleoside, nucleotide (more detail) 12 NA Homo sapiens

GOA TAX018169 GO:0010857 molecular function calcium dependent protein kinase activity Catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the pres (more detail) 12 NA Homo sapiens

GOA TAX030428 GO:0090239 biological process regulation of histone H4 acetylation Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modificatio (more detail) 12 NA Homo sapiens

GOA TAX018950 GO:0016273 molecular function arginine N methyltransferase activity Enables the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine (more detail) 12 NA Homo sapiens

GOA TAX025469 GO:0046133 biological process pyrimidine ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside i (more detail) 12 NA Homo sapiens

GOA IEI003378 Protein protein interactors of human gene DCUN1D3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCUN1D3 (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI005588 Protein protein interactors of human gene GTF2IRD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2IRD1 (SwissProt (more detail) 12 17535438 Homo sapiens

I2D IEI014170 Protein protein interactors of human gene TRAF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRAF7 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI000925 Protein protein interactors of human gene ARRDC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARRDC1 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI011402 Protein protein interactors of human gene RNF150 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF150 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI011635 Protein protein interactors of human gene RRM2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRM2B (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI012861 Protein protein interactors of human gene SPECC1L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPECC1L (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI006896 Protein protein interactors of human gene KLF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF2 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI008128 Protein protein interactors of human gene MPHOSPH10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MPHOSPH10 (SwissProt (more detail) 12 17535438 Homo sapiens

I2D TAX017151 GO:0008250 cellular component oligosaccharyltransferase complex A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers li (more detail) 12 NA Homo sapiens

GOA TAX031127 GO:0098789 biological process pre mRNA cleavage required for polyadenylation The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. (more detail) 12 NA Homo sapiens

GOA TAX024132 GO:0043047 molecular function single stranded telomeric DNA binding Interacting selectively and non-covalently with single-stranded telomere-associated DNA. (more detail) 12 NA Homo sapiens

GOA TAX024153 GO:0043097 biological process pyrimidine nucleoside salvage Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting (more detail) 12 NA Homo sapiens

GOA TAX024184 GO:0043144 biological process snoRNA processing Any process involved in the conversion of a primary small nucleolar RNA (snoRNA) transcript into a m (more detail) 12 NA Homo sapiens

GOA TAX027451 GO:0052803 biological process imidazole containing compound metabolic process The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containi (more detail) 12 NA Homo sapiens

GOA TAX020376 GO:0030208 biological process dermatan sulfate biosynthetic process The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminog (more detail) 12 NA Homo sapiens

GOA IEI015203 Protein protein interactors of human gene ZBTB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI003719 Protein protein interactors of human gene DOCK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DOCK4 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI004090 Protein protein interactors of human gene ELK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELK4 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI005789 Protein protein interactors of human gene HELQ from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HELQ (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI006561 Protein protein interactors of human gene ITPK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ITPK1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI001255 Protein protein interactors of human gene BBX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BBX (SwissProt ID=Q8 (more detail) 12 17535438 Homo sapiens

I2D TAX015866 GO:0005675 cellular component holo TFIIH complex A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the lar (more detail) 12 NA Homo sapiens

GOA IEI003710 Protein protein interactors of human gene DNTT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNTT (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D TAX023784 GO:0042340 biological process keratan sulfate catabolic process The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglyc (more detail) 12 NA Homo sapiens

GOA TAX023824 GO:0042415 biological process norepinephrine metabolic process The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medu (more detail) 12 NA Homo sapiens

GOA TAX019207 GO:0016775 molecular function phosphotransferase activity, nitrogenous group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenou (more detail) 12 NA Homo sapiens

GOA TAX018951 GO:0016274 molecular function protein arginine N methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine (more detail) 12 NA Homo sapiens

GOA IEI009753 Protein protein interactors of human gene PER3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PER3 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D TAX022860 GO:0035404 biological process histone serine phosphorylation The modification of histones by addition of a phosphate group to a serine residue. (more detail) 12 NA Homo sapiens

GOA TAX017614 GO:0009223 biological process pyrimidine deoxyribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, (more detail) 12 NA Homo sapiens

GOA TAX017523 GO:0009125 biological process nucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a comp (more detail) 12 NA Homo sapiens

GOA TAX019732 GO:0019471 biological process 4 hydroxyproline metabolic process The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino a (more detail) 12 NA Homo sapiens

GOA TAX020718 GO:0030914 cellular component STAGA complex A large multiprotein complex that possesses histone acetyltransferase and is involved in regulation (more detail) 12 NA Homo sapiens

GOA TAX028832 GO:0070262 biological process peptidyl serine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine. (more detail) 12 NA Homo sapiens

GOA IEI010833 Protein protein interactors of human gene QTRT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene QTRT2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX021981 GO:0033127 biological process regulation of histone phosphorylation Any process that modulates the frequency, rate or extent of the addition of one or more phosphate gr (more detail) 12 NA Homo sapiens

GOA TAX028916 GO:0070410 molecular function co SMAD binding Interacting selectively and non-covalently with a common mediator SMAD signaling protein. (more detail) 12 NA Homo sapiens

GOA TAX017541 GO:0009143 biological process nucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compo (more detail) 12 NA Homo sapiens

GOA TAX019767 GO:0019627 biological process urea metabolic process The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2. (more detail) 12 NA Homo sapiens

GOA TAX026800 GO:0051103 biological process DNA ligation involved in DNA repair The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, tha (more detail) 12 NA Homo sapiens

GOA TAX020748 GO:0030983 molecular function mismatched DNA binding Interacting selectively and non-covalently with double-stranded DNA containing one or more mismatche (more detail) 12 NA Homo sapiens

GOA TAX030008 GO:0072425 biological process signal transduction involved in G2 DNA damage checkpoint A signal transduction process that contributes to a G2/M transition DNA damage checkpoint. (more detail) 12 NA Homo sapiens

GOA TAX022674 GO:0034969 biological process histone arginine methylation The modification of a histone by addition of a methyl group to an arginine residue. (more detail) 12 NA Homo sapiens

GOA TAX030192 GO:0080182 biological process histone H3 K4 trimethylation The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the his (more detail) 12 NA Homo sapiens

GOA TAX019454 GO:0018065 biological process protein cofactor linkage The covalent attachment of a cofactor to a protein. (more detail) 12 NA Homo sapiens

GOA TAX025721 GO:0046710 biological process GDP metabolic process The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate. (more detail) 12 NA Homo sapiens

GOA IEI004884 Protein protein interactors of human gene FOXP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXP1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI006017 Protein protein interactors of human gene HR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HR (SwissProt ID=O43 (more detail) 12 17535438 Homo sapiens

I2D MEX001806 Genes associated with Kinase Inhibitor Vandetanib Genes associated with Kinase Inhibitor Vandetanib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001209 Genes associated with Kinase Inhibitor 172889 26 8 Genes associated with Kinase Inhibitor 172889-26-8, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MOX012907 Genes associated with Computational Drug Signature Go 6976 Genes associated with Computational Drug Signature Go 6976, curated by the Drug Signature Database ( (more detail) 12 25990557 Homo sapiens

DSigDB FEX001485 Leukemia Li07 12genes DNARepair Supplementary Table1e Genes over-expressed in the highest PKC-? expressing (quartile 4) DLBCL patien (more detail) 12 17313671 Homo sapiens

GeneSigDB TAX001060 Genes annotated by the GO term GO:0008408. Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. (more detail) 12 NA Homo sapiens

MSigDB WIG000570 Non homologous end joining Nonhomologous end joining (NHEJ) eliminates DNA double-strand breaks (DSBs) by direct ligation. NHEJ (more detail) 12 NA Homo sapiens

MSigDB MEX001427 Genes associated with Kinase Inhibitor GSK1326255A Genes associated with Kinase Inhibitor GSK1326255A, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB PEX001140 GST N: Glutathione S transferase, N terminal domain Function: conjugation of reduced glutathione to a variety of targets. Also included in the alignment (more detail) 12 NA Homo sapiens

Pfam TAX013463 GO:0000722 biological process telomere maintenance via recombination Any recombinational process that contributes to the maintenance of proper telomeric length. (more detail) 12 NA Homo sapiens

GOA MEX001931 Genes associated with Kinase Inhibitor GW305178X Genes associated with Kinase Inhibitor GW305178X, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001610 Genes associated with Kinase Inhibitor CHEMBL1965660 Genes associated with Kinase Inhibitor CHEMBL1965660, curated by the Drug Signature Database (DSigDB (more detail) 12 25990557 Homo sapiens

DSigDB MOX003662 Genes associated with Computational Drug Signature Aminolevulinic acid Genes associated with Computational Drug Signature Aminolevulinic acid, curated by the Drug Signatur (more detail) 12 25990557 Homo sapiens

DSigDB TAX013805 GO:0001741 cellular component XY body A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has beco (more detail) 12 NA Homo sapiens

GOA TAX016167 GO:0006171 biological process cAMP biosynthetic process The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, a (more detail) 12 NA Homo sapiens

GOA FEX001162 Immune Kong10 12genes ImmPort TGF betaFamilyMemberReceptors ImmPort genelist of cytokine receptors: TGF-beta Family Member Receptors (more detail) 12 20460173 Homo sapiens

GeneSigDB WAG000909 RNA Polymerase III Transcription Termination (more detail) 12 NA Homo sapiens

Reactome WAG000627 melanocyte development and pigmentation pathway Studies with homozygous knockout mice have suggested that stem cell factor (SCF or KITLG), c-Kit, mi (more detail) 12 NA Homo sapiens

BioCarta TAX001391 Genes annotated by the GO term GO:0016566. Any activity that stops or downregulates transcription of specific genes or sets of genes. (more detail) 12 NA Homo sapiens

MSigDB MAX002909 Examples of transcription factors whose activities are regulated by MAPK1 and MAPK3 [GeneID=5594;5595] phosphorylation. The mitogen-activated protein kinases (MAPKs) are a family of serine/threonine kinases that play an (more detail) 12 NA Homo sapiens

MSigDB TAX000429 Genes annotated by the GO term GO:0007219. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell. (more detail) 12 NA Homo sapiens

MSigDB MEX001944 Genes associated with Kinase Inhibitor GSK1173862A Genes associated with Kinase Inhibitor GSK1173862A, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001510 Genes associated with Kinase Inhibitor go 6983 Genes associated with Kinase Inhibitor go 6983, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MOX003330 Genes associated with Computational Drug Signature AR A014418 Genes associated with Computational Drug Signature AR-A014418, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB WAG000308 RNA Polymerase III Transcription (more detail) 12 NA Homo sapiens

Reactome TAX001244 Genes annotated by the GO term GO:0008235. Catalysis of the hydrolysis of terminal peptide linkages in oligopeptides or polypeptides. Enzymes of this class contain a chelated metal ion essential to their catalytic activity at their active sites. (more detail) 12 NA Homo sapiens

MSigDB MEX002294 Genes associated with Kinase Inhibitor PYRAZOLOPYRIDAZINE 1 Genes associated with Kinase Inhibitor PYRAZOLOPYRIDAZINE 1, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB MEX002002 Genes associated with Kinase Inhibitor Aurora Kinase/Cdk Inhibitor Genes associated with Kinase Inhibitor Aurora Kinase/Cdk Inhibitor, curated by the Drug Signature Da (more detail) 12 25990557 Homo sapiens

DSigDB MEX002408 Genes associated with Kinase Inhibitor Afatinib Genes associated with Kinase Inhibitor Afatinib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB TAX016435 GO:0006568 biological process tryptophan metabolic process The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol- (more detail) 12 NA Homo sapiens

GOA MOX016117 Genes associated with Computational Drug Signature aphidicolin Genes associated with Computational Drug Signature aphidicolin, curated by the Drug Signature Databa (more detail) 12 25990557 Homo sapiens

DSigDB FEX001570 Leukemia Andreeff08 12genes Supplementary Table 7 Genes associated with response to treatment. (more detail) 12 18668134 Homo sapiens

GeneSigDB WIG000367 Lectin Induced Complement Pathway The complement cascade of proteolytic factors involved in cellular lysis can be initiated by several (more detail) 12 NA Homo sapiens

MSigDB TAX000763 Genes annotated by the GO term GO:0046519. The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds. (more detail) 12 NA Homo sapiens

MSigDB WIG000840 Genes involved in FGFR4 ligand binding and activation (more detail) 12 NA Homo sapiens

MSigDB WIG000776 Genes involved in CS/DS degradation (more detail) 12 NA Homo sapiens

MSigDB MEX001913 Genes associated with Kinase Inhibitor Purvalanol B Genes associated with Kinase Inhibitor Purvalanol B, curated by the Drug Signature Database (DSigDB) (more detail) 12 25990557 Homo sapiens

DSigDB WAG001448 Nonhomologous end joining Nonhomologous end joining (NHEJ) elimites D double-strand breaks (DSBs) by direct ligation. NHEJ inv (more detail) 12 NA Homo sapiens

KEGG TAX013280 GO:0000153 cellular component cytoplasmic ubiquitin ligase complex A ubiquitin ligase complex found in the cytoplasm. (more detail) 12 NA Homo sapiens

GOA WIG000839 Genes involved in FGFR2c ligand binding and activation (more detail) 12 NA Homo sapiens

MSigDB MEX002340 Genes associated with Kinase Inhibitor Kinome 10 Genes associated with Kinase Inhibitor Kinome_10, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB PEX000754 Peptidase M10: Matrixin The members of this family are enzymes that cleave peptides. These proteases require zinc for cataly (more detail) 12 NA Homo sapiens

Pfam PEX001246 UCH: Ubiquitin carboxyl terminal hydrolase (more detail) 12 NA Homo sapiens

Pfam WAG000429 il 2 signaling pathway Interleukin 2 (IL-2) is a potent cytokine that can lead to cellular activation and proliferation. IL (more detail) 12 NA Homo sapiens

BioCarta FEX001571 Leukemia Andreeff08 13genes Supplementary Table 8 Differentially expressed genes in AML with 11q23 rearrangements vs. other UNFA (more detail) 12 18668134 Homo sapiens

GeneSigDB WAG001527 RNA Polymerase III Chain Elongation (more detail) 12 NA Homo sapiens

Reactome TAX001382 Genes annotated by the GO term GO:0032182. Interacting selectively and non covalently with a small conjugating protein such as ubiquitin or a ubiquitin like protein. (more detail) 12 NA Homo sapiens

MSigDB WIG001032 Genes involved in Notch HLH transcription pathway (more detail) 12 NA Homo sapiens

MSigDB MEX001423 Genes associated with Kinase Inhibitor Kinome 249 Genes associated with Kinase Inhibitor Kinome_249, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001323 Genes associated with Kinase Inhibitor Tyrphostin AG 1478 Genes associated with Kinase Inhibitor Tyrphostin AG 1478, curated by the Drug Signature Database (D (more detail) 12 25990557 Homo sapiens

DSigDB MEX001933 Genes associated with Kinase Inhibitor rottlerin Genes associated with Kinase Inhibitor rottlerin, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MOX001645 Genes associated with Computational Drug Signature 2,3,4,7,8 PENTACHLORODIBENZOFURAN Genes associated with Computational Drug Signature 2,3,4,7,8-PENTACHLORODIBENZOFURAN, curated by the (more detail) 12 25990557 Homo sapiens

DSigDB MEX001775 Genes associated with Kinase Inhibitor Kinome 3513 Genes associated with Kinase Inhibitor Kinome_3513, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB PEX001280 Methyltransf 25: Methyltransferase domain This family appears to be a methyltransferase domain. (more detail) 12 NA Homo sapiens

Pfam MOX013103 Genes associated with Computational Drug Signature Ilomastat Genes associated with Computational Drug Signature Ilomastat, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB TAX015032 GO:0004185 molecular function serine type carboxypeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the C-terminus of a (more detail) 12 NA Homo sapiens

GOA TAX000035 Genes annotated by the GO term GO:0030521. Any series of molecular signals generated as a consequence of an androgen binding to its receptor. (more detail) 12 NA Homo sapiens

MSigDB FOX000803 Genes in the cancer module 56 (more detail) 12 NA Homo sapiens

MSigDB TAX000985 Genes annotated by the GO term GO:0016363. The dense fibrillar network lying on the inner side of the nuclear membrane. (more detail) 12 NA Homo sapiens

MSigDB WIG001148 Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex (more detail) 12 NA Homo sapiens

MSigDB MEX001644 Genes associated with Kinase Inhibitor 172889 27 9 Genes associated with Kinase Inhibitor 172889-27-9, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001992 Genes associated with Kinase Inhibitor bisindolylmaleimide i Genes associated with Kinase Inhibitor bisindolylmaleimide i, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB MEX002367 Genes associated with Kinase Inhibitor Kinome 501 Genes associated with Kinase Inhibitor Kinome_501, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001816 Genes associated with Kinase Inhibitor Kinome 490 Genes associated with Kinase Inhibitor Kinome_490, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB WAG001481 Circadian rhythm pathway (more detail) 12 NA Homo sapiens

NCI-Nature Curated TAX001062 Genes annotated by the GO term GO:0008376. Catalysis of the transfer of an N acetylgalactosaminyl residue from UDP N acetyl galactosamine to an oligosaccharide. (more detail) 12 NA Homo sapiens

MSigDB TAX001240 Genes annotated by the GO term GO:0004707. Catalysis of the phosphorylation of proteins. Mitogen activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation or differentiation inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli. (more detail) 12 NA Homo sapiens

MSigDB TAX000803 Genes annotated by the GO term GO:0006399. The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. (more detail) 12 NA Homo sapiens

MSigDB WIG001567 Inhibition of Ribosome Biogenesis by p14(ARF) Inhibition of Ribosome Biogenesis by p14(ARF) (more detail) 12 NA Homo sapiens

Protein Lounge TAX001277 Genes annotated by the GO term GO:0008170. Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. (more detail) 12 NA Homo sapiens

MSigDB MEX001329 Genes associated with Kinase Inhibitor Afatinib Genes associated with Kinase Inhibitor Afatinib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001634 Genes associated with Kinase Inhibitor Tandutinib Genes associated with Kinase Inhibitor Tandutinib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB TAX017893 GO:0010288 biological process response to lead ion Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 22 NA Homo sapiens

GOA IEI012254 Protein protein interactors of human gene SKAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SKAP2 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI013683 Protein protein interactors of human gene THRSP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THRSP (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D TAX029905 GO:0072215 biological process regulation of metanephros development Any process that modulates the rate, frequency or extent of metanephros development. Metanephros dev (more detail) 22 NA Homo sapiens

GOA IEI000358 Protein protein interactors of human gene AGK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AGK (SwissProt ID=Q5 (more detail) 22 17535438 Homo sapiens

I2D IEI008238 Protein protein interactors of human gene MRPS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPS2 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI013750 Protein protein interactors of human gene TLE2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLE2 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI003422 Protein protein interactors of human gene DDX3Y from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX3Y (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI004705 Protein protein interactors of human gene FEM1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FEM1B (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI011393 Protein protein interactors of human gene RNF138 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF138 (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D IEI000963 Protein protein interactors of human gene ASB5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASB5 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI011963 Protein protein interactors of human gene SELENOS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SELENOS (SwissProt I (more detail) 22 17535438 Homo sapiens

I2D IEI009972 Protein protein interactors of human gene PITX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PITX2 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI000764 Protein protein interactors of human gene APRT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APRT (SwissProt ID=P (more detail) 22 17535438 Homo sapiens

I2D IEI003757 Protein protein interactors of human gene DPP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DPP3 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI008259 Protein protein interactors of human gene MRTFA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRTFA (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D MOX001725 Genes associated with Computational Drug Signature Aluminium sulfate Genes associated with Computational Drug Signature Aluminium sulfate, curated by the Drug Signature (more detail) 22 25990557 Homo sapiens

DSigDB WIG000485 beta Alanine metabolism (more detail) 22 NA Homo sapiens

MSigDB WIG001195 Genes involved in Signaling by BMP (more detail) 22 NA Homo sapiens

MSigDB WIG000807 Genes involved in Downregulation of TGF beta receptor signaling (more detail) 22 NA Homo sapiens

MSigDB MOX011939 Genes associated with Computational Drug Signature cholecalciferol Genes associated with Computational Drug Signature cholecalciferol, curated by the Drug Signature Da (more detail) 22 25990557 Homo sapiens

DSigDB MOX001716 Genes associated with Computational Drug Signature rosmarinic acid Genes associated with Computational Drug Signature rosmarinic acid, curated by the Drug Signature Da (more detail) 22 25990557 Homo sapiens

DSigDB MAX000475 Cancer related genes down regulated in any of four hepatoma cell lines following 24 h treatment with TSA [PubChem=5562]. OBJECTIVE: Histone deacetylase (HDAC) inhibitors have been reported to induce cell growth arrest, ap (more detail) 22 NA Homo sapiens

MSigDB MAX000265 Growth factor signaling components up regulated in hepatocellular carcinoma (HCC). Dysregulation of pleiotropic growth factors, receptors and their downstream signaling pathway compon (more detail) 22 NA Homo sapiens

MSigDB MOX003646 Genes associated with Computational Drug Signature aldrin Genes associated with Computational Drug Signature aldrin, curated by the Drug Signature Database (D (more detail) 22 25990557 Homo sapiens

DSigDB IEI009356 Protein protein interactors of human gene OSGIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OSGIN1 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D TAX020624 GO:0030687 cellular component preribosome, large subunit precursor A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins inc (more detail) 24 NA Homo sapiens

GOA TAX023016 GO:0035666 biological process TRIF dependent toll like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where (more detail) 24 NA Homo sapiens

GOA IEI012976 Protein protein interactors of human gene SRP54 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRP54 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI015585 Protein protein interactors of human gene ZNF510 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF510 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D IEI009541 Protein protein interactors of human gene PBK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PBK (SwissProt ID=Q9 (more detail) 24 17535438 Homo sapiens

I2D IEI002297 Protein protein interactors of human gene CDYL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDYL (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D IEI012134 Protein protein interactors of human gene SH2B2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH2B2 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI014933 Protein protein interactors of human gene VRK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VRK2 (SwissProt ID=Q (more detail) 24 17535438 Homo sapiens

I2D IEI010402 Protein protein interactors of human gene PPP4R3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP4R3A (SwissProt I (more detail) 24 17535438 Homo sapiens

I2D IEI002732 Protein protein interactors of human gene CNOT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNOT2 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D TAX030335 GO:0090103 biological process cochlea morphogenesis The process in which the cochlea is generated and organized. (more detail) 24 NA Homo sapiens

GOA TAX025109 GO:0045445 biological process myoblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A (more detail) 24 NA Homo sapiens

GOA TAX021965 GO:0033081 biological process regulation of T cell differentiation in thymus Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus. (more detail) 24 NA Homo sapiens

GOA IEI001941 Protein protein interactors of human gene CCDC22 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCDC22 (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D IEI006154 Protein protein interactors of human gene IDH3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IDH3B (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI006226 Protein protein interactors of human gene IGF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGF2 (SwissProt ID=P (more detail) 24 17535438 Homo sapiens

I2D IEI003128 Protein protein interactors of human gene CTPS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTPS2 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D WIG000505 Dorso ventral axis formation (more detail) 24 NA Homo sapiens

MSigDB TAX000522 Genes annotated by the GO term GO:0051091. Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription. (more detail) 24 NA Homo sapiens

MSigDB FEX010385 hsa miR 4278 HITS-CLIP, Functional MTI (Weak) (more detail) 24 NA Homo sapiens

mirTARbase WIG000197 Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. na (more detail) 24 NA Homo sapiens

MSigDB FEX002389 MultipleMyeloma Gutierrez10 29genes Table 4 Potential microRNA (miRNA)?mRNA interactions deregulated in the multiple myeloma (MM) with m (more detail) 24 20054351 Homo sapiens

GeneSigDB MOX005911 Genes associated with Computational Drug Signature 3 O Methylquercetin Genes associated with Computational Drug Signature 3-O-Methylquercetin, curated by the Drug Signatur (more detail) 24 25990557 Homo sapiens

DSigDB FEX003493 Viral Cairo08 25genes Table S5. Overrepresented pathways (p (more detail) 24 19061838 Homo sapiens

GeneSigDB FEX001061 HeadandNeck Sok03 31genes Table 3d. Gene Descriptions of HNSCCA(head and neck squamous cell carcinomas)-related genes with P (more detail) 24 12874079 Homo sapiens

GeneSigDB MOX007294 Genes associated with Computational Drug Signature biochanin A Genes associated with Computational Drug Signature biochanin A, curated by the Drug Signature Databa (more detail) 24 25990557 Homo sapiens

DSigDB TAX022451 GO:0034377 biological process plasma lipoprotein particle assembly The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein par (more detail) 26 NA Homo sapiens

GOA TAX019376 GO:0017091 molecular function AU rich element binding Interacting selectively and non-covalently with a region of RNA containing frequent adenine and urid (more detail) 26 NA Homo sapiens

GOA IEI008849 Protein protein interactors of human gene NKAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NKAP (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens

I2D TAX021688 GO:0032647 biological process regulation of interferon alpha production Any process that modulates the frequency, rate, or extent of interferon-alpha production. (more detail) 26 NA Homo sapiens

GOA IEI012289 Protein protein interactors of human gene SLC16A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC16A1 (SwissProt I (more detail) 26 17535438 Homo sapiens

I2D IEI005273 Protein protein interactors of human gene GLUL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLUL (SwissProt ID=P (more detail) 26 17535438 Homo sapiens

I2D IEI010007 Protein protein interactors of human gene PLA2G2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLA2G2A (SwissProt I (more detail) 26 17535438 Homo sapiens

I2D IEI008968 Protein protein interactors of human gene NPAS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NPAS2 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D IEI014990 Protein protein interactors of human gene WDR20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR20 (SwissProt ID= (more detail) 26 17535438 Homo sapiens

I2D TAX023038 GO:0035710 biological process CD4 positive, alpha beta T cell activation The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure t (more detail) 26 NA Homo sapiens

GOA IEI015874 Protein protein interactors of human gene ZZZ3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZZZ3 (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens

I2D MOX017807 Genes associated with Computational Drug Signature Temsirolimus Genes associated with Computational Drug Signature Temsirolimus, curated by the Drug Signature Datab (more detail) 26 25990557 Homo sapiens

DSigDB FEX001665 Leukemia Nath10 26genes Table 1. Gene expression profiling of Jurkat T cells treated with p-NO-ASA (the para isomer of NO-do (more detail) 26 20188076 Homo sapiens

GeneSigDB FEX000651 Breast Liu08 26genes Table 4: Expression of cell cycle genes in breast cancers. (more detail) 26 18786252 Homo sapiens

GeneSigDB WIG000192 VEGFR1 specific signals (more detail) 26 NA Homo sapiens

MSigDB MAX000011 Genes up regulated in HUVEC cells (endothelium) at 30 min after VEGFA [GeneID=7422] stimulation. Vascular endothelial growth factor (VEGF) is one of the most important factors that stimulate angiog (more detail) 26 NA Homo sapiens

MSigDB WAG001063 Trk receptor signaling mediated by PI3K and PLC gamma (more detail) 26 NA Homo sapiens

NCI-Nature Curated MOX002269 Genes associated with Computational Drug Signature Tyrphostin 23 Genes associated with Computational Drug Signature Tyrphostin 23, curated by the Drug Signature Data (more detail) 26 25990557 Homo sapiens

DSigDB PEX001075 ubiquitin: Ubiquitin family This family contains a number of ubiquitin-like proteins: SUMO (smt3 homologue) (see Swiss:Q02724), (more detail) 26 NA Homo sapiens

Pfam MOX015667 Genes associated with Computational Drug Signature Tyrphostin 23 Genes associated with Computational Drug Signature Tyrphostin 23, curated by the Drug Signature Data (more detail) 26 25990557 Homo sapiens

DSigDB MOX013270 Genes associated with Computational Drug Signature kenpaullone Genes associated with Computational Drug Signature kenpaullone, curated by the Drug Signature Databa (more detail) 26 25990557 Homo sapiens

DSigDB MEX000357 Genes associated with Approved Drug estradiol Genes associated with Approved Drug estradiol, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens

DSigDB WIG001569 iNOS Signaling iNOS Signaling (more detail) 26 NA Homo sapiens

Protein Lounge FEX001596 Leukemia Tsai08 30genes Table 2 Details of the selected genes by the frequency-based method for the Leukemia data set (more detail) 26 18842155 Homo sapiens

GeneSigDB TAX031934 GO:1900409 biological process positive regulation of cellular response to oxidative stress Any process that activates or increases the frequency, rate or extent of cellular response to oxidat (more detail) 17 NA Homo sapiens

GOA IEI003180 Protein protein interactors of human gene CXCL10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CXCL10 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI011421 Protein protein interactors of human gene RNF19A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF19A (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D TAX030562 GO:0090545 cellular component CHD type complex A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) famil (more detail) 17 NA Homo sapiens

GOA TAX019107 GO:0016581 cellular component NuRD complex An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activi (more detail) 17 NA Homo sapiens

GOA TAX022634 GO:0034719 cellular component SMN Sm protein complex A protein complex formed by the association of several methylated Sm proteins with the SMN complex; (more detail) 17 NA Homo sapiens

GOA IEI011095 Protein protein interactors of human gene RBM4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM4B (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI013344 Protein protein interactors of human gene TAF1C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF1C (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX025954 GO:0047617 molecular function acyl CoA hydrolase activity Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate. (more detail) 17 NA Homo sapiens

GOA IEI008920 Protein protein interactors of human gene NOC3L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOC3L (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI009501 Protein protein interactors of human gene PARN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PARN (SwissProt ID=O (more detail) 17 17535438 Homo sapiens

I2D IEI003978 Protein protein interactors of human gene EFNA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFNA1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI011085 Protein protein interactors of human gene RBM34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM34 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI004563 Protein protein interactors of human gene FAN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAN1 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D TAX027582 GO:0055106 molecular function ubiquitin protein transferase regulator activity Modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent att (more detail) 17 NA Homo sapiens

GOA IEI008855 Protein protein interactors of human gene NKIRAS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NKIRAS1 (SwissProt I (more detail) 17 17535438 Homo sapiens

I2D IEI007716 Protein protein interactors of human gene MARCHF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MARCHF7 (SwissProt I (more detail) 17 17535438 Homo sapiens

I2D TAX020783 GO:0031061 biological process negative regulation of histone methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition (more detail) 17 NA Homo sapiens

GOA TAX028170 GO:0060850 biological process regulation of transcription involved in cell fate commitment Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II (more detail) 17 NA Homo sapiens

GOA IEI006925 Protein protein interactors of human gene KLHL22 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHL22 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI013773 Protein protein interactors of human gene TLX3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLX3 (SwissProt ID=O (more detail) 17 17535438 Homo sapiens

I2D IEI001432 Protein protein interactors of human gene BRF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRF1 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D TAX020391 GO:0030224 biological process monocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized feat (more detail) 17 NA Homo sapiens

GOA TAX032809 GO:1903131 biological process mononuclear cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mononucl (more detail) 17 NA Homo sapiens

GOA IEI012786 Protein protein interactors of human gene SOX6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SOX6 (SwissProt ID=P (more detail) 17 17535438 Homo sapiens

I2D IEI013535 Protein protein interactors of human gene TEAD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TEAD1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX020787 GO:0031065 biological process positive regulation of histone deacetylation Any process that activates or increases the frequency, rate or extent of the removal of acetyl group (more detail) 17 NA Homo sapiens

GOA TAX034496 GO:2000136 biological process regulation of cell proliferation involved in heart morphogenesis Any process that modulates the frequency, rate or extent of cell proliferation involved in heart mor (more detail) 17 NA Homo sapiens

GOA IEI009450 Protein protein interactors of human gene PAGR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAGR1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI009453 Protein protein interactors of human gene PAIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAIP1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI003287 Protein protein interactors of human gene DACH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DACH1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI010346 Protein protein interactors of human gene PPP1R14A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R14A (SwissProt (more detail) 17 17535438 Homo sapiens

I2D IEI014655 Protein protein interactors of human gene UFL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UFL1 (SwissProt ID=O (more detail) 17 17535438 Homo sapiens

I2D IEI015826 Protein protein interactors of human gene ZNRF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNRF1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI008793 Protein protein interactors of human gene NFIL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFIL3 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D MOX000593 Genes associated with Computational Drug Signature tranilast Genes associated with Computational Drug Signature tranilast, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens

DSigDB MOX013108 Genes associated with Computational Drug Signature Imatinib Genes associated with Computational Drug Signature Imatinib, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens

DSigDB MAX001131 Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive ALL (B and T lineage ALL); here genes down regulated in the drug resistant samples. Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percen (more detail) 17 NA Homo sapiens

MSigDB MOX002364 Genes associated with Computational Drug Signature o6 benzylguanine Genes associated with Computational Drug Signature o6-benzylguanine, curated by the Drug Signature D (more detail) 17 25990557 Homo sapiens

DSigDB TAX000049 Genes annotated by the GO term GO:0006576. The chemical reactions and pathways involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. (more detail) 17 NA Homo sapiens

MSigDB TAX000046 Genes annotated by the GO term GO:0006284. In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. (more detail) 17 NA Homo sapiens

MSigDB MOX000752 Genes associated with Computational Drug Signature estradiol valerate Genes associated with Computational Drug Signature estradiol valerate, curated by the Drug Signature (more detail) 17 25990557 Homo sapiens

DSigDB WAG000006 regulation of cell cycle progression by plk3 The focus of this pathway is to illustrate the role of Polo-like Kise 3 (Plk3 also known as Prk and (more detail) 17 NA Homo sapiens

BioCarta WIG000359 IL 7 Signal Transduction IL-7 is a key cytokine in the immune system, essential for normal development of B cells and T cells (more detail) 17 NA Homo sapiens

MSigDB TAX014620 GO:0003181 biological process atrioventricular valve morphogenesis The process in which the structure of the atrioventricular valve is generated and organized. (more detail) 17 NA Homo sapiens

GOA WIG000244 The 4 1BB dependent immune response The activation of T cells requires a co-stimulatory signal with T cell receptor activation, provided (more detail) 17 NA Homo sapiens

MSigDB WIG000609 Renin angiotensin system (more detail) 17 NA Homo sapiens

MSigDB MOX003478 Genes associated with Computational Drug Signature NVP TAE684 Genes associated with Computational Drug Signature NVP-TAE684, curated by the Drug Signature Databas (more detail) 17 25990557 Homo sapiens

DSigDB MOX008552 Genes associated with Computational Drug Signature CHEMBL199925 Genes associated with Computational Drug Signature CHEMBL199925, curated by the Drug Signature Datab (more detail) 17 25990557 Homo sapiens

DSigDB MOX006928 Genes associated with Computational Drug Signature alsterpaullone Genes associated with Computational Drug Signature alsterpaullone, curated by the Drug Signature Dat (more detail) 17 25990557 Homo sapiens

DSigDB MAX001553 Components of RNA post transcriptional modification machinery up regulated in MDA MB 435 cells (breast cancer) whose metastatic potential has been reduced by expression of NME1 [GeneID=4830]. The role of Gemin5 in alternative mRNA splicing, tumor cell motility, and proteomic instability was (more detail) 17 NA Homo sapiens

MSigDB TAX000993 Genes annotated by the GO term GO:0044452. Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. (more detail) 17 NA Homo sapiens

MSigDB MEX000735 Genes associated with Approved Drug prochlorperazine edisylate Genes associated with Approved Drug prochlorperazine edisylate, curated by the Drug Signature Databa (more detail) 17 25990557 Homo sapiens

DSigDB MOX004184 Genes associated with Computational Drug Signature HEXACHLOROBENZENE Genes associated with Computational Drug Signature HEXACHLOROBENZENE, curated by the Drug Signature (more detail) 17 25990557 Homo sapiens

DSigDB MOX014722 Genes associated with Computational Drug Signature quinalizarin Genes associated with Computational Drug Signature quinalizarin, curated by the Drug Signature Datab (more detail) 17 25990557 Homo sapiens

DSigDB TAX001415 Genes annotated by the GO term GO:0046966. Interacting selectively with a thyroid hormone receptor. (more detail) 17 NA Homo sapiens

MSigDB WAG000992 Renin angiotensin system (more detail) 17 NA Homo sapiens

KEGG MAX002558 Genes encoding substrates of IkappaB kinase (IKK) complex. Transcription factors of the NF-kappaB family regulate hundreds of genes in the context of multiple (more detail) 17 NA Homo sapiens

MSigDB WIG001201 Genes involved in Signaling by FGFR1 fusion mutants (more detail) 17 NA Homo sapiens

MSigDB WIG001124 Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor (more detail) 17 NA Homo sapiens

MSigDB MOX001972 Genes associated with Computational Drug Signature curcumin II Genes associated with Computational Drug Signature curcumin II, curated by the Drug Signature Databa (more detail) 17 25990557 Homo sapiens

DSigDB TAX025141 GO:0045577 biological process regulation of B cell differentiation Any process that modulates the frequency, rate or extent of B cell differentiation. (more detail) 28 NA Homo sapiens

GOA TAX019405 GO:0017145 biological process stem cell division The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or (more detail) 28 NA Homo sapiens

GOA IEI014857 Protein protein interactors of human gene VCPIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VCPIP1 (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D IEI014999 Protein protein interactors of human gene WDR36 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR36 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI007959 Protein protein interactors of human gene MGRN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MGRN1 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI000341 Protein protein interactors of human gene AFG3L2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AFG3L2 (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D TAX021955 GO:0033048 biological process negative regulation of mitotic sister chromatid segregation Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segre (more detail) 28 NA Homo sapiens

GOA IEI008310 Protein protein interactors of human gene MTAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTAP (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI008448 Protein protein interactors of human gene MYL12B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYL12B (SwissProt ID (more detail) 28 17535438 Homo sapiens

I2D IEI013448 Protein protein interactors of human gene TBL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBL3 (SwissProt ID=Q (more detail) 28 17535438 Homo sapiens

I2D IEI002185 Protein protein interactors of human gene CDC40 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC40 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D IEI007273 Protein protein interactors of human gene LIMD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LIMD1 (SwissProt ID= (more detail) 28 17535438 Homo sapiens

I2D MOX000184 Genes associated with Computational Drug Signature juglone Genes associated with Computational Drug Signature juglone, curated by the Drug Signature Database ( (more detail) 28 25990557 Homo sapiens

DSigDB WAG001317 Downstream TCR signaling (more detail) 28 NA Homo sapiens

Reactome MEX000942 Genes associated with Approved Drug methysergide maleate Genes associated with Approved Drug methysergide maleate, curated by the Drug Signature Database (DS (more detail) 28 25990557 Homo sapiens

DSigDB FEX002418 Ovarian Clarke04 28genes Table 1. Gene expression affected by (more detail) 28 15452549 Homo sapiens

GeneSigDB MOX003678 Genes associated with Computational Drug Signature Amrinone Genes associated with Computational Drug Signature Amrinone, curated by the Drug Signature Database (more detail) 28 25990557 Homo sapiens

DSigDB WAG000625 phospholipids as signalling intermediaries Sphingosine-1-phosphate (S1P) is an example of lipid messengers with both intracellular and extracel (more detail) 28 NA Homo sapiens

BioCarta MOX003706 Genes associated with Computational Drug Signature NSC321521 Genes associated with Computational Drug Signature NSC321521, curated by the Drug Signature Database (more detail) 28 25990557 Homo sapiens

DSigDB TAX014638 GO:0003208 biological process cardiac ventricle morphogenesis The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives (more detail) 28 NA Homo sapiens

GOA MOX000195 Genes associated with Computational Drug Signature Chinomethionate Genes associated with Computational Drug Signature Chinomethionate, curated by the Drug Signature Da (more detail) 28 25990557 Homo sapiens

DSigDB TAX016287 GO:0006376 biological process mRNA splice site selection Selection of a splice site by components of the assembling spliceosome. (more detail) 28 NA Homo sapiens

GOA FEX003217 Stomach Hofsli05 30genes Table 2b. Genes significantlya regulated by (b) gastrin and not by HGF and (c) HGF and not by gastri (more detail) 28 15846300 Homo sapiens

GeneSigDB MOX000219 Genes associated with Computational Drug Signature Honokiol Genes associated with Computational Drug Signature Honokiol, curated by the Drug Signature Database (more detail) 28 25990557 Homo sapiens

DSigDB MAX001669 Genes un methylated aberrantly in HCT116 and Colo320 (colon cancer) cells. Aberrant CpG methylation of tumor suppressor gene regulatory elements is associated with transcripti (more detail) 28 NA Homo sapiens

MSigDB MOX004897 Genes associated with Computational Drug Signature Epirubicin Genes associated with Computational Drug Signature Epirubicin, curated by the Drug Signature Databas (more detail) 28 25990557 Homo sapiens

DSigDB WIG001915 Cell Differentiation meta Cell Differentiation - meta (more detail) 19 NA Homo sapiens

WikiPathway MOX014565 Genes associated with Computational Drug Signature Plumbagin Genes associated with Computational Drug Signature Plumbagin, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB MEX000368 Genes associated with Approved Drug spironolactone Genes associated with Approved Drug spironolactone, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB FEX003048 Stemcell Lee08 21genes Supplementary Table 2. Differentially expressed proteins relating to RNA post transcriptional modifi (more detail) 19 18245461 Homo sapiens

GeneSigDB TAX000652 Genes annotated by the GO term GO:0045637. Any process that modulates the frequency, rate or extent of myeloid cell differentiation. (more detail) 19 NA Homo sapiens

MSigDB WIG000445 TGF beta signaling pathway TGF-beta regulates growth and proliferation of cells, blocking growth of many cell types. The TGF-be (more detail) 19 NA Homo sapiens

MSigDB WAG000007 role of mal in rho mediated activation of srf Serum response factor (SRF) is a transcription factor, which binds to a serum response element (SRE) (more detail) 19 NA Homo sapiens

BioCarta MAX001135 Genes distinguishing vincristine [PubChem=5978] resistant and sensitive ALL (B and T lineage ALL); here genes down regulated in the drug resistant samples. Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percen (more detail) 19 NA Homo sapiens

MSigDB MOX003103 Genes associated with Computational Drug Signature RH 1 Genes associated with Computational Drug Signature RH 1, curated by the Drug Signature Database (DSi (more detail) 19 25990557 Homo sapiens

DSigDB MOX001113 Genes associated with Computational Drug Signature Methoxycamptothecin Genes associated with Computational Drug Signature Methoxycamptothecin, curated by the Drug Signatur (more detail) 19 25990557 Homo sapiens

DSigDB WIG000371 Role of MAL in Rho Mediated Activation of SRF Serum response factor (SRF) is a transcription factor, which binds to a serum response element (SRE) (more detail) 19 NA Homo sapiens

MSigDB FEX001456 Leukemia Camos06 22genes Table 1b Genes with a significant differential expression level (overexpressed and underexpressed) i (more detail) 19 16849538 Homo sapiens

GeneSigDB MOX016511 Genes associated with Computational Drug Signature CEFIXIME Genes associated with Computational Drug Signature CEFIXIME, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB MEX000291 Genes associated with Approved Drug pyrimethamine Genes associated with Approved Drug pyrimethamine, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB MOX014068 Genes associated with Computational Drug Signature norepinephrine Genes associated with Computational Drug Signature norepinephrine, curated by the Drug Signature Dat (more detail) 19 25990557 Homo sapiens

DSigDB MOX004244 Genes associated with Computational Drug Signature ketamine Genes associated with Computational Drug Signature ketamine, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB MEX000603 Genes associated with Approved Drug simvastatin Genes associated with Approved Drug simvastatin, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens

DSigDB TAX019698 GO:0019370 biological process leukotriene biosynthetic process The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically a (more detail) 19 NA Homo sapiens

GOA TAX025290 GO:0045821 biological process positive regulation of glycolytic process Any process that activates or increases the frequency, rate or extent of glycolysis. (more detail) 19 NA Homo sapiens

GOA IEI008426 Protein protein interactors of human gene MYEF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYEF2 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI012877 Protein protein interactors of human gene SPIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPIN1 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX026265 GO:0048645 biological process animal organ formation The process pertaining to the initial formation of an animal organ from unspecified parts. The proce (more detail) 19 NA Homo sapiens

GOA TAX019777 GO:0019682 biological process glyceraldehyde 3 phosphate metabolic process The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate (more detail) 19 NA Homo sapiens

GOA TAX019211 GO:0016780 molecular function phosphotransferase activity, for other substituted phosphate groups Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl re (more detail) 19 NA Homo sapiens

GOA IEI006429 Protein protein interactors of human gene INTS11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS11 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI011109 Protein protein interactors of human gene RBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBP1 (SwissProt ID=P (more detail) 19 17535438 Homo sapiens

I2D IEI015366 Protein protein interactors of human gene ZMYM3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZMYM3 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI001072 Protein protein interactors of human gene ATP2B1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP2B1 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI006419 Protein protein interactors of human gene INSIG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INSIG1 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI015792 Protein protein interactors of human gene ZNF827 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF827 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI011352 Protein protein interactors of human gene RMI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RMI1 (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D IEI008523 Protein protein interactors of human gene NAA20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NAA20 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI000965 Protein protein interactors of human gene ASB7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASB7 (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D IEI006845 Protein protein interactors of human gene KIF4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIF4A (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI011090 Protein protein interactors of human gene RBM42 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM42 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI007165 Protein protein interactors of human gene LBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LBP (SwissProt ID=P1 (more detail) 19 17535438 Homo sapiens

I2D TAX027178 GO:0051769 biological process regulation of nitric oxide synthase biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 19 NA Homo sapiens

GOA IEI008162 Protein protein interactors of human gene MRC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRC2 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI000951 Protein protein interactors of human gene ASB11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASB11 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI011994 Protein protein interactors of human gene SENP8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SENP8 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI005910 Protein protein interactors of human gene HMGN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMGN2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI001437 Protein protein interactors of human gene BRINP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRINP1 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI008927 Protein protein interactors of human gene NOL11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOL11 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI003558 Protein protein interactors of human gene DIO2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIO2 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI005584 Protein protein interactors of human gene GTF2H3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2H3 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI006430 Protein protein interactors of human gene INTS12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS12 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI011567 Protein protein interactors of human gene RPRD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPRD2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI014616 Protein protein interactors of human gene UBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBP1 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D TAX022561 GO:0034616 biological process response to laminar fluid shear stress Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 14 NA Homo sapiens

GOA TAX019385 GO:0017110 molecular function nucleoside diphosphatase activity Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate. (more detail) 14 NA Homo sapiens

GOA IEI015003 Protein protein interactors of human gene WDR43 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR43 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI002565 Protein protein interactors of human gene CIR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CIR1 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI009506 Protein protein interactors of human gene PARP14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PARP14 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI003359 Protein protein interactors of human gene DCLRE1C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCLRE1C (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI013477 Protein protein interactors of human gene TCEAL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TCEAL4 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI000728 Protein protein interactors of human gene APMAP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APMAP (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI000799 Protein protein interactors of human gene ARGLU1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARGLU1 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI006781 Protein protein interactors of human gene KHK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KHK (SwissProt ID=P5 (more detail) 14 17535438 Homo sapiens

I2D TAX019705 GO:0019377 biological process glycolipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-ac (more detail) 14 NA Homo sapiens

GOA IEI001752 Protein protein interactors of human gene CAMK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAMK4 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI008903 Protein protein interactors of human gene NMNAT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NMNAT1 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI010205 Protein protein interactors of human gene POLK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLK (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI004120 Protein protein interactors of human gene ELSPBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELSPBP1 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI004648 Protein protein interactors of human gene FBXO38 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO38 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI005392 Protein protein interactors of human gene GPATCH8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GPATCH8 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI006919 Protein protein interactors of human gene KLHL15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHL15 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D TAX025326 GO:0045898 biological process regulation of RNA polymerase II transcriptional preinitiation complex assembly Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preini (more detail) 14 NA Homo sapiens

GOA WAG001290 Cell Cycle, Mitotic (more detail) 14 NA Homo sapiens

Reactome WAG001325 M/G1 Transition (more detail) 14 NA Homo sapiens

Reactome TAX001136 Genes annotated by the GO term GO:0019239. Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3). (more detail) 14 NA Homo sapiens

MSigDB FEX001819 Lung Yuan04 14genes Table 1a. Alterations in Gene Expression in NCI-H522 Cells Treated by 5-Aza-dC: Genes downregulated (more detail) 14 15256063 Homo sapiens

GeneSigDB MEX001428 Genes associated with Kinase Inhibitor Imatinib Genes associated with Kinase Inhibitor Imatinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX015812 Genes associated with Computational Drug Signature Valstar Genes associated with Computational Drug Signature Valstar, curated by the Drug Signature Database ( (more detail) 14 25990557 Homo sapiens

DSigDB WAG001486 Assembly of the pre replicative complex (more detail) 14 NA Homo sapiens

Reactome FEX002302 Lymphoma Staege08 26genes Figure 2a. Examples of Hodgkin (more detail) 14 18400362 Homo sapiens

GeneSigDB WIG000676 Genes involved in Acyl chain remodelling of PI (more detail) 14 NA Homo sapiens

MSigDB WIG001444 Checkpoint Comparative Pathways Checkpoint Comparative Pathways (more detail) 14 NA Homo sapiens

Protein Lounge MEX000415 Genes associated with Approved Drug trifluridine Genes associated with Approved Drug trifluridine, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX003477 Genes associated with Computational Drug Signature Pazopanib Genes associated with Computational Drug Signature Pazopanib, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB MEX000511 Genes associated with Approved Drug cladribine Genes associated with Approved Drug cladribine, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB PEX001173 zf C3HC4 3: Zinc finger, C3HC4 type (RING finger) (more detail) 14 NA Homo sapiens

Pfam PEX001911 Sulfotransfer 1: Sulfotransferase domain (more detail) 14 NA Homo sapiens

Pfam WAG001077 Apoptotic cleavage of cellular proteins (more detail) 14 NA Homo sapiens

Reactome FEX001254 Leukemia Li02 16genes Table 3. Partially Up-Regulated Genes in Patients with CML (more detail) 14 12041670 Homo sapiens

GeneSigDB TAX000365 Genes annotated by the GO term GO:0002573. The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. (more detail) 14 NA Homo sapiens

MSigDB WIG000281 CD40L Signaling Pathway The CD40 receptor was first associated with expression in B cells and the role it plays through its (more detail) 14 NA Homo sapiens

MSigDB WIG001494 Extrinsic Prothrombin Activation Pathway Extrinsic Prothrombin Activation Pathway (more detail) 14 NA Homo sapiens

Protein Lounge WIG000096 IL5 mediated signaling events (more detail) 14 NA Homo sapiens

MSigDB MOX004907 Genes associated with Computational Drug Signature NIMUSTINE Genes associated with Computational Drug Signature NIMUSTINE, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB WIG001256 Genes involved in Synthesis of substrates in N glycan biosythesis (more detail) 14 NA Homo sapiens

MSigDB TAX001014 Genes annotated by the GO term GO:0016605. A class of nuclear body; they react against SP100 auto antibodies (PML, promyelocytic leukemia); cells typically contain 10 30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection. (more detail) 14 NA Homo sapiens

MSigDB MEX002411 Genes associated with Kinase Inhibitor Imatinib Genes associated with Kinase Inhibitor Imatinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX002289 Genes associated with Computational Drug Signature Dibenzoylmethane Genes associated with Computational Drug Signature Dibenzoylmethane, curated by the Drug Signature D (more detail) 14 25990557 Homo sapiens

DSigDB WAG000642 cadmium induces dna synthesis and proliferation in macrophages Exposure to divalent cadmium ions (Cd2+) is a known cancer risk factor, but the molecular mechanisms (more detail) 14 NA Homo sapiens

BioCarta WAG000077 DNA Replication Pre Initiation (more detail) 14 NA Homo sapiens

Reactome MAX000922 Genes encoding the NF kB core signaling proteins. This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-kap (more detail) 14 NA Homo sapiens

MSigDB TAX013609 GO:0001091 molecular function RNA polymerase II basal transcription factor binding Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, any (more detail) 14 NA Homo sapiens

GOA TAX015222 GO:0004559 molecular function alpha mannosidase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides (more detail) 14 NA Homo sapiens

GOA WAG000802 N Glycan degradation (more detail) 14 NA Homo sapiens

KEGG WAG001502 G1/S Transition (more detail) 14 NA Homo sapiens

Reactome IEI010146 Protein protein interactors of human gene PMPCB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PMPCB (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D TAX018182 GO:0010874 biological process regulation of cholesterol efflux Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux i (more detail) 21 NA Homo sapiens

GOA TAX031106 GO:0098743 biological process cell aggregation The clustering together and adhesion of initially separate cells to form an aggregate. Examples inc (more detail) 21 NA Homo sapiens

GOA IEI010258 Protein protein interactors of human gene POP7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POP7 (SwissProt ID=O (more detail) 21 17535438 Homo sapiens

I2D IEI003013 Protein protein interactors of human gene CRY2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CRY2 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI009025 Protein protein interactors of human gene NR1I3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR1I3 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI014593 Protein protein interactors of human gene UBE2T from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2T (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI013579 Protein protein interactors of human gene TET3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TET3 (SwissProt ID=O (more detail) 21 17535438 Homo sapiens

I2D IEI005105 Protein protein interactors of human gene GCDH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GCDH (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D TAX024847 GO:0044788 biological process modulation by host of viral process A process in which a host organism modulates the frequency, rate or extent of any of a process being (more detail) 21 NA Homo sapiens

GOA IEI005945 Protein protein interactors of human gene HNRNPLL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HNRNPLL (SwissProt I (more detail) 21 17535438 Homo sapiens

I2D TAX020837 GO:0031128 biological process developmental induction A developmental process involving two tissues in which one tissue (the inducer) produces a signal th (more detail) 21 NA Homo sapiens

GOA IEI000878 Protein protein interactors of human gene ARL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARL2 (SwissProt ID=P (more detail) 21 17535438 Homo sapiens

I2D IEI001264 Protein protein interactors of human gene BCAS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCAS3 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI001825 Protein protein interactors of human gene CASP8AP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CASP8AP2 (SwissProt (more detail) 21 17535438 Homo sapiens

I2D IEI003327 Protein protein interactors of human gene DCAF11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCAF11 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI003591 Protein protein interactors of human gene DLGAP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLGAP3 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI006578 Protein protein interactors of human gene JADE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JADE1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI010464 Protein protein interactors of human gene PRIM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRIM1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI015165 Protein protein interactors of human gene YOD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YOD1 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI004084 Protein protein interactors of human gene ELF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELF4 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D MOX000537 Genes associated with Computational Drug Signature propachlor Genes associated with Computational Drug Signature propachlor, curated by the Drug Signature Databas (more detail) 21 25990557 Homo sapiens

DSigDB MOX003712 Genes associated with Computational Drug Signature Azinphos methyl Genes associated with Computational Drug Signature Azinphos-methyl, curated by the Drug Signature Da (more detail) 21 25990557 Homo sapiens

DSigDB MOX000452 Genes associated with Computational Drug Signature tolfenamic acid Genes associated with Computational Drug Signature tolfenamic acid, curated by the Drug Signature Da (more detail) 21 25990557 Homo sapiens

DSigDB MEX003602 Genes associated with Perturbagen Signature metoclopramide Genes associated with Perturbagen Signature metoclopramide, curated by the Drug Signature Database ( (more detail) 21 25990557 Homo sapiens

DSigDB MOX004071 Genes associated with Computational Drug Signature ethoxyquin Genes associated with Computational Drug Signature ethoxyquin, curated by the Drug Signature Databas (more detail) 21 25990557 Homo sapiens

DSigDB MOX003195 Genes associated with Computational Drug Signature SCH 202676 hydrobromide Genes associated with Computational Drug Signature SCH-202676 hydrobromide, curated by the Drug Sign (more detail) 21 25990557 Homo sapiens

DSigDB MOX000169 Genes associated with Computational Drug Signature hypericin Genes associated with Computational Drug Signature hypericin, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens

DSigDB WIG001284 Genes involved in TRAF6 mediated NF kB activation (more detail) 21 NA Homo sapiens

MSigDB WAG001030 the information processing pathway at the ifn beta enhancer The packaging of eukaryotic D into nucleosomes inhibits the access of factors to D and results in th (more detail) 21 NA Homo sapiens

BioCarta TAX024888 GO:0045006 biological process DNA deamination The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosi (more detail) 11 NA Homo sapiens

GOA IEI015051 Protein protein interactors of human gene WFS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WFS1 (SwissProt ID=O (more detail) 11 17535438 Homo sapiens

I2D IEI002971 Protein protein interactors of human gene CREB3L3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CREB3L3 (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D IEI004026 Protein protein interactors of human gene EIF2AK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF2AK3 (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D IEI012882 Protein protein interactors of human gene SPINDOC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPINDOC (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D TAX016573 GO:0006751 biological process glutathione catabolic process The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutam (more detail) 11 NA Homo sapiens

GOA TAX018923 GO:0016233 biological process telomere capping A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome (more detail) 11 NA Homo sapiens

GOA TAX025410 GO:0046040 biological process IMP metabolic process The chemical reactions and pathways involving IMP, inosine monophosphate. (more detail) 11 NA Homo sapiens

GOA IEI000866 Protein protein interactors of human gene ARID5B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARID5B (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D TAX029261 GO:0071027 biological process nuclear RNA surveillance The set of processes involved in identifying and degrading defective or aberrant RNAs within the nuc (more detail) 11 NA Homo sapiens

GOA TAX028492 GO:0061578 molecular function Lys63 specific deubiquitinase activity Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein. (more detail) 11 NA Homo sapiens

GOA IEI011353 Protein protein interactors of human gene RMI2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RMI2 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI001628 Protein protein interactors of human gene C5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C5 (SwissProt ID=P01 (more detail) 11 17535438 Homo sapiens

I2D TAX021790 GO:0032799 biological process low density lipoprotein receptor particle metabolic process The chemical reactions and pathways involving low-density lipoprotein receptors. (more detail) 11 NA Homo sapiens

GOA TAX030592 GO:0090656 biological process t circle formation A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t (more detail) 11 NA Homo sapiens

GOA TAX024863 GO:0044819 biological process mitotic G1/S transition checkpoint A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part (more detail) 11 NA Homo sapiens

GOA TAX019803 GO:0019774 cellular component proteasome core complex, beta subunit complex The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. (more detail) 11 NA Homo sapiens

GOA TAX032423 GO:1902222 biological process erythrose 4 phosphate/phosphoenolpyruvate family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolp (more detail) 11 NA Homo sapiens

GOA TAX017810 GO:0009931 molecular function calcium dependent protein serine/threonine kinase activity Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a pro (more detail) 11 NA Homo sapiens

GOA TAX019457 GO:0018095 biological process protein polyglutamylation The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glut (more detail) 11 NA Homo sapiens

GOA TAX019234 GO:0016813 molecular function hydrolase activity, acting on carbon nitrogen (but not peptide) bonds, in linear amidines Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound (more detail) 11 NA Homo sapiens

GOA TAX025414 GO:0046051 biological process UTP metabolic process The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate. (more detail) 11 NA Homo sapiens

GOA TAX027301 GO:0051974 biological process negative regulation of telomerase activity Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reac (more detail) 11 NA Homo sapiens

GOA TAX020834 GO:0031125 biological process rRNA 3' end processing Any process involved in forming the mature 3' end of an rRNA molecule. (more detail) 11 NA Homo sapiens

GOA TAX034367 GO:1990825 molecular function sequence specific mRNA binding Interacting selectively and non-covalently with messenger RNA (mRNA) of a specific nucleotide compos (more detail) 11 NA Homo sapiens

GOA TAX035020 GO:2001034 biological process positive regulation of double strand break repair via nonhomologous end joining Any process that activates or increases the frequency, rate or extent of double-strand break repair (more detail) 11 NA Homo sapiens

GOA IEI015263 Protein protein interactors of human gene ZCCHC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZCCHC3 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI009536 Protein protein interactors of human gene PAX9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAX9 (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D IEI015824 Protein protein interactors of human gene ZNHIT6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNHIT6 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI011564 Protein protein interactors of human gene RPP40 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPP40 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI000557 Protein protein interactors of human gene ANAPC15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC15 (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D IEI001331 Protein protein interactors of human gene BHLHE41 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BHLHE41 (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D TAX026503 GO:0050667 biological process homocysteine metabolic process The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercapt (more detail) 11 NA Homo sapiens

GOA IEI005102 Protein protein interactors of human gene GCAT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GCAT (SwissProt ID=O (more detail) 11 17535438 Homo sapiens

I2D IEI005975 Protein protein interactors of human gene HOXB4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXB4 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI001010 Protein protein interactors of human gene ATAD5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATAD5 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI014876 Protein protein interactors of human gene VGLL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VGLL4 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D TAX017549 GO:0009151 biological process purine deoxyribonucleotide metabolic process The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of d (more detail) 11 NA Homo sapiens

GOA TAX017676 GO:0009396 biological process folic acid containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of folic acid and its derivatives. (more detail) 11 NA Homo sapiens

GOA TAX025037 GO:0045259 cellular component proton transporting ATP synthase complex A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP dur (more detail) 11 NA Homo sapiens

GOA TAX032422 GO:1902221 biological process erythrose 4 phosphate/phosphoenolpyruvate family amino acid metabolic process The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino (more detail) 11 NA Homo sapiens

GOA TAX021301 GO:0032041 molecular function NAD dependent histone deacetylase activity (H3 K14 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine ( (more detail) 11 NA Homo sapiens

GOA TAX023502 GO:0038110 biological process interleukin 2 mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-2 to a receptor on the surface (more detail) 11 NA Homo sapiens

GOA TAX019284 GO:0016888 molecular function endodeoxyribonuclease activity, producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal bre (more detail) 11 NA Homo sapiens

GOA IEI009086 Protein protein interactors of human gene NSMCE3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NSMCE3 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI003921 Protein protein interactors of human gene ECM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ECM1 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI004133 Protein protein interactors of human gene EME1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EME1 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI013771 Protein protein interactors of human gene TLX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TLX1 (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D IEI007759 Protein protein interactors of human gene MBD3L2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MBD3L2 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI008535 Protein protein interactors of human gene NABP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NABP1 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D TAX034254 GO:1990440 biological process positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress Any process that activates or increases the frequency, rate or extent of transcription from an RNA p (more detail) 11 NA Homo sapiens

GOA IEI010281 Protein protein interactors of human gene POU3F2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POU3F2 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI005598 Protein protein interactors of human gene GTPBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTPBP1 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI006232 Protein protein interactors of human gene IGFBP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGFBP1 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D TAX017559 GO:0009162 biological process deoxyribonucleoside monophosphate metabolic process The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consis (more detail) 11 NA Homo sapiens

GOA TAX019086 GO:0016553 biological process base conversion or substitution editing Any base modification or substitution events that result in alterations in the coding potential or s (more detail) 11 NA Homo sapiens

GOA TAX024844 GO:0044783 biological process G1 DNA damage checkpoint A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase in the (more detail) 11 NA Homo sapiens

GOA TAX023893 GO:0042555 cellular component MCM complex A hexameric protein complex required for the initiation and regulation of DNA replication. (more detail) 11 NA Homo sapiens

GOA TAX020794 GO:0031078 molecular function histone deacetylase activity (H3 K14 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine ( (more detail) 11 NA Homo sapiens

GOA IEI009084 Protein protein interactors of human gene NSMCE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NSMCE1 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI005576 Protein protein interactors of human gene GTF2A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2A2 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI000071 Protein protein interactors of human gene ABHD14B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABHD14B (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D TAX027747 GO:0060218 biological process hematopoietic stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hematopoieti (more detail) 11 NA Homo sapiens

GOA TAX030586 GO:0090646 biological process mitochondrial tRNA processing The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an ami (more detail) 11 NA Homo sapiens

GOA TAX030321 GO:0090085 biological process regulation of protein deubiquitination Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiq (more detail) 11 NA Homo sapiens

GOA TAX023196 GO:0035999 biological process tetrahydrofolate interconversion The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydr (more detail) 11 NA Homo sapiens

GOA TAX016266 GO:0006346 biological process methylation dependent chromatin silencing Repression of transcription by methylation of DNA, leading to the formation of heterochromatin. (more detail) 11 NA Homo sapiens

GOA TAX024627 GO:0044213 molecular function intronic transcription regulatory region DNA binding Interacting selectively and non-covalently with an intronic DNA region that regulates the transcript (more detail) 11 NA Homo sapiens

GOA TAX001048 Genes annotated by the GO term GO:0005689. The minor (U12 dependent) spliceosome is composed of the snRNPs, U11, U12, U4atac, U6atac, and U5 (which is also a component of the major spliceosome). This minor form of the spliceosome is responsible for the splicing of the majority of introns with atypical AT AC terminal dinucleotides, as well as other non canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site. (more detail) 11 NA Homo sapiens

MSigDB WIG001576 Alternative Complement Pathway Alternative Complement Pathway (more detail) 11 NA Homo sapiens

Protein Lounge TAX000444 Genes annotated by the GO term GO:0031365. The alteration of the N terminal amino acid residue in a protein. (more detail) 11 NA Homo sapiens

MSigDB WIG000738 Genes involved in CDC6 association with the ORC:origin complex (more detail) 11 NA Homo sapiens

MSigDB WIG001763 Lectin Induced Complement Pathway Lectin Induced Complement Pathway (more detail) 11 NA Homo sapiens

Protein Lounge MEX001817 Genes associated with Kinase Inhibitor alsterpaullone Genes associated with Kinase Inhibitor alsterpaullone, curated by the Drug Signature Database (DSigD (more detail) 11 25990557 Homo sapiens

DSigDB TAX016426 GO:0006559 biological process L phenylalanine catabolic process The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpro (more detail) 11 NA Homo sapiens

GOA TAX013598 GO:0001055 molecular function RNA polymerase II activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA (more detail) 11 NA Homo sapiens

GOA TAX014637 GO:0003207 biological process cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac chamber from unspecified (more detail) 11 NA Homo sapiens

GOA TAX016136 GO:0006107 biological process oxaloacetate metabolic process The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an imp (more detail) 11 NA Homo sapiens

GOA PEX002167 HMG box: HMG (high mobility group) box (more detail) 11 NA Homo sapiens

Pfam TAX015108 GO:0004385 molecular function guanylate kinase activity Catalysis of the reaction: ATP + GMP = ADP + GDP. (more detail) 11 NA Homo sapiens

GOA TAX016175 GO:0006183 biological process GTP biosynthetic process The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate. (more detail) 11 NA Homo sapiens

GOA TAX015253 GO:0004596 molecular function peptide alpha N acetyltransferase activity Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the (more detail) 11 NA Homo sapiens

GOA WAG001372 SLBP Dependent Processing of Replication Dependent Histone Pre mRNAs (more detail) 11 NA Homo sapiens

Reactome TAX000233 Genes annotated by the GO term GO:0006007. The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco hexose. (more detail) 11 NA Homo sapiens

MSigDB WIG001312 Genes involved in Unwinding of DNA (more detail) 11 NA Homo sapiens

MSigDB TAX001444 Genes annotated by the GO term GO:0043130. Interacting selectively and non covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. (more detail) 11 NA Homo sapiens

MSigDB WIG001194 Genes involved in Signaling by activated point mutants of FGFR1 (more detail) 11 NA Homo sapiens

MSigDB MEX002233 Genes associated with Kinase Inhibitor CHEMBL1969102 Genes associated with Kinase Inhibitor CHEMBL1969102, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens

DSigDB MEX001687 Genes associated with Kinase Inhibitor Saracatinib Genes associated with Kinase Inhibitor Saracatinib, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB TAX014102 GO:0002178 cellular component palmitoyltransferase complex A protein complex with palmitoyltransferase activity. (more detail) 11 NA Homo sapiens

GOA TAX015875 GO:0005687 cellular component U4 snRNP A ribonucleoprotein complex that contains small nuclear RNA U4. (more detail) 11 NA Homo sapiens

GOA MOX014978 Genes associated with Computational Drug Signature Saracatinib Genes associated with Computational Drug Signature Saracatinib, curated by the Drug Signature Databa (more detail) 11 25990557 Homo sapiens

DSigDB WIG001203 Genes involved in Signaling by FGFR3 mutants (more detail) 11 NA Homo sapiens

MSigDB MEX001244 Genes associated with Kinase Inhibitor 761437 28 9 Genes associated with Kinase Inhibitor 761437-28-9, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MOX012940 Genes associated with Computational Drug Signature GSK690693 Genes associated with Computational Drug Signature GSK690693, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens

DSigDB TAX016420 GO:0006553 biological process lysine metabolic process The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid. (more detail) 11 NA Homo sapiens

GOA TAX016516 GO:0006670 biological process sphingosine metabolic process The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-o (more detail) 11 NA Homo sapiens

GOA TAX013995 GO:0002003 biological process angiotensin maturation The process leading to the attainment of the full functional capacity of angiotensin by conversion o (more detail) 11 NA Homo sapiens

GOA TAX013642 GO:0001206 molecular function distal enhancer DNA binding transcription repressor activity, RNA polymerase II specific A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA (more detail) 11 NA Homo sapiens

GOA TAX013231 GO:0000050 biological process urea cycle The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield ure (more detail) 11 NA Homo sapiens

GOA WAG000850 mechanisms of transcriptional repression by dna methylation Tumorigenesis is known to be a multistep process in which defects in various cancer genes accumulate (more detail) 11 NA Homo sapiens

BioCarta TAX000178 Genes annotated by the GO term GO:0006304. The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. (more detail) 11 NA Homo sapiens

MSigDB TAX000554 Genes annotated by the GO term GO:0051604. The process leading to the attainment of the full functional capacity of a protein. (more detail) 11 NA Homo sapiens

MSigDB MAX001794 Genes identified with the Fanconi anemia (FA) and the FA pathway. Fanconi anaemia (FA) is a rare recessive disorder associated with chromosomal fragility, aplastic an (more detail) 11 NA Homo sapiens

MSigDB MEX002305 Genes associated with Kinase Inhibitor Kinome 248 Genes associated with Kinase Inhibitor Kinome_248, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MOX002281 Genes associated with Computational Drug Signature Eldecalcitol Genes associated with Computational Drug Signature Eldecalcitol, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens

DSigDB TAX016350 GO:0006465 biological process signal peptide processing The proteolytic removal of a signal peptide from a protein during or after transport to a specific l (more detail) 11 NA Homo sapiens

GOA TAX016376 GO:0006501 biological process C terminal protein lipidation The covalent attachment of a lipid group to the carboxy terminus of a protein. (more detail) 11 NA Homo sapiens

GOA TAX016430 GO:0006563 biological process L serine metabolic process The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amin (more detail) 11 NA Homo sapiens

GOA TAX013871 GO:0001833 biological process inner cell mass cell proliferation The proliferation of cells in the inner cell mass. (more detail) 11 NA Homo sapiens

GOA TAX015907 GO:0005753 cellular component mitochondrial proton transporting ATP synthase complex A proton-transporting ATP synthase complex found in the mitochondrial membrane. (more detail) 11 NA Homo sapiens

GOA WIG001452 Cleavage and Polyadenylation of Pre mRNA Cleavage and Polyadenylation of Pre-mRNA (more detail) 11 NA Homo sapiens

Protein Lounge WIG000396 Deregulation of CDK5 in Alzheimers Disease Cyclin-dependent kinase 5 (cdk5), a multi-functional kinase, and its neuron-specific activator p35 a (more detail) 11 NA Homo sapiens

MSigDB WIG000308 Map Kinase Inactivation of SMRT Corepressor Corepressors are coregulators that interact with transcriptional silencers in a variety of pathways (more detail) 11 NA Homo sapiens

MSigDB TAX001266 Genes annotated by the GO term GO:0004715. Catalysis of the reaction: ATP + a protein L tyrosine = ADP + a protein L tyrosine phosphate. (more detail) 11 NA Homo sapiens

MSigDB WIG000956 Genes involved in Keratan sulfate degradation (more detail) 11 NA Homo sapiens

MSigDB MEX001255 Genes associated with Kinase Inhibitor Kinome 1199 Genes associated with Kinase Inhibitor Kinome_1199, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MEX001348 Genes associated with Kinase Inhibitor GW589933X Genes associated with Kinase Inhibitor GW589933X, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MOX001108 Genes associated with Computational Drug Signature Arsenic acid Genes associated with Computational Drug Signature Arsenic acid, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens

DSigDB MEX001674 Genes associated with Kinase Inhibitor InSolutionÃ‚Â¿Ã‚Â¿KT5720 Genes associated with Kinase Inhibitor InSolutionÃ‚Â¿Ã‚Â¿KT5720, curated by the Drug Signa (more detail) 11 25990557 Homo sapiens

DSigDB MOX000562 Genes associated with Computational Drug Signature Diethyl sulfate Genes associated with Computational Drug Signature Diethyl sulfate, curated by the Drug Signature Da (more detail) 11 25990557 Homo sapiens

DSigDB MOX000409 Genes associated with Computational Drug Signature PIMARIC ACID Genes associated with Computational Drug Signature PIMARIC ACID, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens

DSigDB WAG000242 lectin induced complement pathway The complement cascade of proteolytic factors involved in cellular lysis can be initiated by several (more detail) 11 NA Homo sapiens

BioCarta TAX000243 Genes annotated by the GO term GO:0006687. The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide. (more detail) 11 NA Homo sapiens

MSigDB WIG001231 Genes involved in SLBP Dependent Processing of Replication Dependent Histone Pre mRNAs (more detail) 11 NA Homo sapiens

MSigDB WIG000999 Genes involved in mRNA Decay by 3' to 5' Exoribonuclease (more detail) 11 NA Homo sapiens

MSigDB TAX000694 Genes annotated by the GO term GO:0050792. Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts. (more detail) 11 NA Homo sapiens

MSigDB MEX000630 Genes associated with Approved Drug gemcitabine hydrochloride Genes associated with Approved Drug gemcitabine hydrochloride, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens

DSigDB MOX009947 Genes associated with Computational Drug Signature CHEMBL380598 Genes associated with Computational Drug Signature CHEMBL380598, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens

DSigDB TAX016454 GO:0006590 biological process thyroid hormone generation The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodo (more detail) 11 NA Homo sapiens

GOA TAX013656 GO:0001325 biological process formation of extrachromosomal circular DNA Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not (more detail) 11 NA Homo sapiens

GOA MEX001269 Genes associated with Kinase Inhibitor A 443654 Genes associated with Kinase Inhibitor A-443654, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MEX002211 Genes associated with Kinase Inhibitor Kinome 812 Genes associated with Kinase Inhibitor Kinome_812, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MEX001927 Genes associated with Kinase Inhibitor Kinome 528 Genes associated with Kinase Inhibitor Kinome_528, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MEX001820 Genes associated with Kinase Inhibitor CHEMBL1970317 Genes associated with Kinase Inhibitor CHEMBL1970317, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens

DSigDB MEX001836 Genes associated with Kinase Inhibitor CHEMBL456252 Genes associated with Kinase Inhibitor CHEMBL456252, curated by the Drug Signature Database (DSigDB) (more detail) 11 25990557 Homo sapiens

DSigDB TAX016425 GO:0006558 biological process L phenylalanine metabolic process The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylp (more detail) 11 NA Homo sapiens

GOA TAX014178 GO:0002320 biological process lymphoid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a lymphoid progenito (more detail) 11 NA Homo sapiens

GOA TAX013627 GO:0001161 molecular function intronic transcription regulatory region sequence specific DNA binding Interacting selectively and non-covalently with an intronic DNA sequence that regulates the transcri (more detail) 11 NA Homo sapiens

GOA WAG001439 Circadian rhythm Circadian rhythm is an interl biological clock, which ebles to sustain an approximately 24-hour rhyt (more detail) 11 NA Homo sapiens

KEGG TAX001108 Genes annotated by the GO term GO:0004180. Catalysis of the hydrolytic cleavage of the terminal or penultimate peptide bond at the C terminal end of a peptide or polypeptide. (more detail) 11 NA Homo sapiens

MSigDB WIG000283 Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway Map kinases transduce responses to extracellular signals by a variety of routes, and communicate wit (more detail) 11 NA Homo sapiens

MSigDB FOX000544 Genes in the cancer module 211 (more detail) 11 NA Homo sapiens

MSigDB TAX000918 Genes annotated by the GO term GO:0032039. A protein complex that stably associates with the C terminus of RNA polymerase II and mediates 3' end processing of small nuclear RNAs generated by RNA polymerase II. (more detail) 11 NA Homo sapiens

MSigDB MAX002130 Genes within amplicon 7p15 identified in a copy number alterations study of 191 breast tumor samples. A single cancer cell contains large numbers of genetic alterations that in combination create the ma (more detail) 11 NA Homo sapiens

MSigDB TAX000443 Genes annotated by the GO term GO:0006044. The chemical reactions and pathways involving N acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide moiety of a glycoprotein. (more detail) 11 NA Homo sapiens

MSigDB TAX000254 Genes annotated by the GO term GO:0042168. The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. (more detail) 11 NA Homo sapiens

MSigDB TAX001151 Genes annotated by the GO term GO:0016893. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5' phosphomonoesters. (more detail) 11 NA Homo sapiens

MSigDB TAX000241 Genes annotated by the GO term GO:0006516. The chemical reactions and pathways resulting in the breakdown of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues other than as a moiety of nucleic acid; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. (more detail) 11 NA Homo sapiens

MSigDB WIG001118 Genes involved in Pyrimidine catabolism (more detail) 11 NA Homo sapiens

MSigDB MEX000413 Genes associated with Approved Drug ampicillin Genes associated with Approved Drug ampicillin, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MEX001625 Genes associated with Kinase Inhibitor PDK1/Akt/Flt Dual Pathway Inhibitor Genes associated with Kinase Inhibitor PDK1/Akt/Flt Dual Pathway Inhibitor, curated by the Drug Sign (more detail) 11 25990557 Homo sapiens

DSigDB MEX001639 Genes associated with Kinase Inhibitor Ruboxistaurin Genes associated with Kinase Inhibitor Ruboxistaurin, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens

DSigDB MEX001203 Genes associated with Kinase Inhibitor Cdk2 Inhibitor IV, NU6140 Genes associated with Kinase Inhibitor Cdk2 Inhibitor IV, NU6140, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens

DSigDB MOX000825 Genes associated with Computational Drug Signature Lead dinitrate Genes associated with Computational Drug Signature Lead dinitrate, curated by the Drug Signature Dat (more detail) 11 25990557 Homo sapiens

DSigDB MOX004688 Genes associated with Computational Drug Signature streptonigrin Genes associated with Computational Drug Signature streptonigrin, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens

DSigDB TAX013347 GO:0000288 biological process nuclear transcribed mRNA catabolic process, deadenylation dependent decay A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordere (more detail) 11 NA Homo sapiens

GOA FEX001486 Leukemia Li07 12genes DNA/RNAProteinSynthesis Supplementary Table1f Genes over-expressed in the highest PKC-? expressing (quartile 4) DLBCL patien (more detail) 11 17313671 Homo sapiens

GeneSigDB WIG000434 Activation of Src by Protein tyrosine phosphatase alpha Progression through the cell cycle is accompanied by activation of the proto-oncogene c-Src, a prote (more detail) 11 NA Homo sapiens

MSigDB TAX000125 Genes annotated by the GO term GO:0006672. The chemical reactions and pathways involving ceramides, any N acylated sphingoid. (more detail) 11 NA Homo sapiens

MSigDB TAX001091 Genes annotated by the GO term GO:0004003. Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of the DNA helix. (more detail) 11 NA Homo sapiens

MSigDB TAX000560 Genes annotated by the GO term GO:0000209. Addition of multiple ubiquitin moieties to a protein, forming a ubiquitin chain. (more detail) 11 NA Homo sapiens

MSigDB TAX023884 GO:0042537 biological process benzene containing compound metabolic process The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, co (more detail) 23 NA Homo sapiens

GOA TAX017112 GO:0008187 molecular function poly pyrimidine tract binding Interacting selectively and non-covalently with any stretch of pyrimidines (cytosine or uracil) in a (more detail) 23 NA Homo sapiens

GOA IEI006026 Protein protein interactors of human gene HRNR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HRNR (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D IEI004135 Protein protein interactors of human gene EMG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EMG1 (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D IEI015210 Protein protein interactors of human gene ZBTB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB3 (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI006342 Protein protein interactors of human gene IL2RA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL2RA (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D TAX016940 GO:0007492 biological process endoderm development The process whose specific outcome is the progression of the endoderm over time, from its formation (more detail) 23 NA Homo sapiens

GOA IEI006197 Protein protein interactors of human gene IFNGR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFNGR1 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI004846 Protein protein interactors of human gene FNTA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FNTA (SwissProt ID=P (more detail) 23 17535438 Homo sapiens

I2D IEI010972 Protein protein interactors of human gene RALYL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RALYL (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI001499 Protein protein interactors of human gene BZW2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BZW2 (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D IEI014521 Protein protein interactors of human gene TXNIP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TXNIP (SwissProt ID= (more detail) 23 17535438 Homo sapiens

I2D IEI014223 Protein protein interactors of human gene TRIM17 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM17 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D IEI008618 Protein protein interactors of human gene NCDN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCDN (SwissProt ID=Q (more detail) 23 17535438 Homo sapiens

I2D IEI002999 Protein protein interactors of human gene CRNKL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CRNKL1 (SwissProt ID (more detail) 23 17535438 Homo sapiens

I2D TAX032371 GO:1902100 biological process negative regulation of metaphase/anaphase transition of cell cycle Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase tran (more detail) 23 NA Homo sapiens

GOA MAX003179 Genes down regulated by expression of HBV X protein (HBVgp3) [GeneID=944566] in SK Hep 1 cells (hepatocellular carcinoma). Hepatitis B virus (HBV) is a major risk factor for the development of hepatocellular carcinoma (HCC) (more detail) 23 NA Homo sapiens

MSigDB MOX007465 Genes associated with Computational Drug Signature camptothecin Genes associated with Computational Drug Signature camptothecin, curated by the Drug Signature Datab (more detail) 23 25990557 Homo sapiens

DSigDB FEX003368 Viral Sun01 27genes SignalTransduction Related TABLE 1. Expression Profile of Signal Transduction-Related Genes in BC-2 Cells and Its Effect by MAP (more detail) 23 11573962 Homo sapiens

GeneSigDB WAG000036 Calcium signaling in the CD4+ TCR pathway (more detail) 23 NA Homo sapiens

NCI-Nature Curated TAX015274 GO:0004622 molecular function lysophospholipase activity Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate. (more detail) 23 NA Homo sapiens

GOA MOX017753 Genes associated with Computational Drug Signature PAPAVERINE HYDROCHLORIDE Genes associated with Computational Drug Signature PAPAVERINE HYDROCHLORIDE, curated by the Drug Sig (more detail) 23 25990557 Homo sapiens

DSigDB FOX000165 Neighborhood of MBD4 Neighborhood of MBD4 methyl-CpG binding domain protein 4 in the GNF2 expression compendium (more detail) 23 NA Homo sapiens

MSigDB TAX000176 Genes annotated by the GO term GO:0031570. Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure. (more detail) 23 NA Homo sapiens

MSigDB FEX001178 InVitro Haouzi10 24genes Supplemental Table S2. List of growth factor (B) genes significantly modulated during the endometria (more detail) 23 20042535 Homo sapiens

GeneSigDB MOX016565 Genes associated with Computational Drug Signature sulindac Genes associated with Computational Drug Signature sulindac, curated by the Drug Signature Database (more detail) 23 25990557 Homo sapiens

DSigDB WIG000296 CTCF: First Multivalent Nuclear Factor CTCF is central to signaling pathways in immature B cells elicited by cross-linking the Ig BCR and s (more detail) 23 NA Homo sapiens

MSigDB FEX003384 Viral Baran Marszak02 26genes Table 3. Decreased expression (26 genes); Genbank Accession Number Mean of EBV+/EBV- Ratio and Name (more detail) 23 12429807 Homo sapiens

GeneSigDB WIG000421 Ras Signaling Pathway Ras activates many signaling cascades. Here we illustrate some of the well-characterized cascades in (more detail) 23 NA Homo sapiens

MSigDB WIG000403 Regulation of PGC 1a Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1a) is a tissue-specific c (more detail) 23 NA Homo sapiens

MSigDB FEX000055 Bone Ohali04 26genes Table 3. Selected over-expressed genes in the microarray-based poor prognosis signature ES patients (more detail) 23 15467746 Homo sapiens

GeneSigDB WIG000147 Signaling events mediated by PRL (more detail) 23 NA Homo sapiens

MSigDB MOX002971 Genes associated with Computational Drug Signature 4,5,6,7 tetrabromobenzotriazole Genes associated with Computational Drug Signature 4,5,6,7-tetrabromobenzotriazole, curated by the D (more detail) 23 25990557 Homo sapiens

DSigDB IEI005408 Protein protein interactors of human gene GPKOW from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GPKOW (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI005655 Protein protein interactors of human gene H2AC7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AC7 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D TAX021485 GO:0032369 biological process negative regulation of lipid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement (more detail) 25 NA Homo sapiens

GOA IEI000370 Protein protein interactors of human gene AGPS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AGPS (SwissProt ID=O (more detail) 25 17535438 Homo sapiens

I2D IEI015143 Protein protein interactors of human gene YARS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YARS1 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D TAX025362 GO:0045940 biological process positive regulation of steroid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 25 NA Homo sapiens

GOA IEI014065 Protein protein interactors of human gene TNS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNS3 (SwissProt ID=Q (more detail) 25 17535438 Homo sapiens

I2D IEI009744 Protein protein interactors of human gene PELI2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PELI2 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D TAX023243 GO:0036075 biological process replacement ossification Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation. (more detail) 25 NA Homo sapiens

GOA IEI014513 Protein protein interactors of human gene TXNDC11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TXNDC11 (SwissProt I (more detail) 25 17535438 Homo sapiens

I2D IEI003385 Protein protein interactors of human gene DDAH2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDAH2 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D IEI014932 Protein protein interactors of human gene VRK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VRK1 (SwissProt ID=Q (more detail) 25 17535438 Homo sapiens

I2D TAX024116 GO:0043027 molecular function cysteine type endopeptidase inhibitor activity involved in apoptotic process Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic p (more detail) 25 NA Homo sapiens

GOA IEI009691 Protein protein interactors of human gene PDIA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDIA2 (SwissProt ID= (more detail) 25 17535438 Homo sapiens

I2D FEX001784 Lung McDoniels Silversar 26genes Table 2. Differentially Expressed Genes in Adenocarcinomas and Squamous Cell Carcinomas. (more detail) 25 11896569 Homo sapiens

GeneSigDB MEX002605 Genes associated with Perturbagen Signature amprolium Genes associated with Perturbagen Signature amprolium, curated by the Drug Signature Database (DSigD (more detail) 25 25990557 Homo sapiens

DSigDB WIG000186 Endogenous TLR signaling (more detail) 25 NA Homo sapiens

MSigDB MOX016074 Genes associated with Computational Drug Signature 3,4 dichloroisocoumarin Genes associated with Computational Drug Signature 3,4-dichloroisocoumarin, curated by the Drug Sign (more detail) 25 25990557 Homo sapiens

DSigDB MOX003193 Genes associated with Computational Drug Signature Lu 19005 Genes associated with Computational Drug Signature Lu 19005, curated by the Drug Signature Database (more detail) 25 25990557 Homo sapiens

DSigDB MAX001661 'Wilm's tumor signature': genes highly expressed in Wilm's tumor samples compared to normal fetal kidney and a heterologous tumor, Burkit lymphoma. Wilms' tumor (WT) has been considered a prototype for arrested cellular differentiation in cancer, b (more detail) 25 NA Homo sapiens

MSigDB WIG000230 Interleukin 4 (IL 4) Pathway na (more detail) 25 NA Homo sapiens

MSigDB FEX001215 Kidney Shi04 29genes Table 1 Differentially Expressed Genes in RE Treated RCC 54 (more detail) 25 15280659 Homo sapiens

GeneSigDB TAX013963 GO:0001958 biological process endochondral ossification Replacement ossification wherein bone tissue replaces cartilage. (more detail) 25 NA Homo sapiens

GOA MOX000886 Genes associated with Computational Drug Signature ipriflavone Genes associated with Computational Drug Signature ipriflavone, curated by the Drug Signature Databa (more detail) 25 25990557 Homo sapiens

DSigDB MOX004039 Genes associated with Computational Drug Signature EMETINE Genes associated with Computational Drug Signature EMETINE, curated by the Drug Signature Database ( (more detail) 25 25990557 Homo sapiens

DSigDB FEX001865 Lung Noh05 43genes Table 1a. NHBE cells present different gene expression profiles in response to trichostatin A treatm (more detail) 27 16357148 Homo sapiens

GeneSigDB MAX002844 Genes up regulated in Caco 2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 2h. Shigella invades the human intestinal mucosa, thus causing bacillary dysentery, an acute recto-colit (more detail) 27 NA Homo sapiens

MSigDB MOX007515 Genes associated with Computational Drug Signature catechol Genes associated with Computational Drug Signature catechol, curated by the Drug Signature Database (more detail) 27 25990557 Homo sapiens

DSigDB MOX004512 Genes associated with Computational Drug Signature phenylbutazone Genes associated with Computational Drug Signature phenylbutazone, curated by the Drug Signature Dat (more detail) 27 25990557 Homo sapiens

DSigDB MOX001581 Genes associated with Computational Drug Signature Galangin Genes associated with Computational Drug Signature Galangin, curated by the Drug Signature Database (more detail) 27 25990557 Homo sapiens

DSigDB WIG001601 Nur77 Signaling in T Cell Nur77 Signaling in T-Cell (more detail) 27 NA Homo sapiens

Protein Lounge WIG000307 Phospholipids as signalling intermediaries Sphingosine-1-phosphate (S1P) is an example of lipid messengers with both intracellular and extracel (more detail) 27 NA Homo sapiens

MSigDB WIG001704 Toll Comparative Pathway Toll Comparative Pathway (more detail) 27 NA Homo sapiens

Protein Lounge MOX005086 Genes associated with Computational Drug Signature benzoic acid Genes associated with Computational Drug Signature benzoic acid, curated by the Drug Signature Datab (more detail) 27 25990557 Homo sapiens

DSigDB MOX003156 Genes associated with Computational Drug Signature 2,6,9,9 tetramethylcycloundeca 2,6,10 trien 1 one Genes associated with Computational Drug Signature 2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one (more detail) 27 25990557 Homo sapiens

DSigDB MOX003128 Genes associated with Computational Drug Signature CI 1040 Genes associated with Computational Drug Signature CI-1040, curated by the Drug Signature Database ( (more detail) 27 25990557 Homo sapiens

DSigDB MOX001009 Genes associated with Computational Drug Signature Dienogest Genes associated with Computational Drug Signature Dienogest, curated by the Drug Signature Database (more detail) 27 25990557 Homo sapiens

DSigDB FEX000845 Colon VanErk04 34genes Table 2. Early response genes in HT29 cells after exposure to high concentration of curcumin (100 ?m (more detail) 27 15140256 Homo sapiens

GeneSigDB MOX012122 Genes associated with Computational Drug Signature cyclosporin A Genes associated with Computational Drug Signature cyclosporin A, curated by the Drug Signature Data (more detail) 27 25990557 Homo sapiens

DSigDB IEI008389 Protein protein interactors of human gene MUL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MUL1 (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D IEI014501 Protein protein interactors of human gene TWF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TWF1 (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D IEI008180 Protein protein interactors of human gene MRPL10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPL10 (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D IEI012655 Protein protein interactors of human gene SMYD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMYD3 (SwissProt ID= (more detail) 27 17535438 Homo sapiens

I2D TAX025151 GO:0045589 biological process regulation of regulatory T cell differentiation Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells. (more detail) 27 NA Homo sapiens

GOA TAX019783 GO:0019707 molecular function protein cysteine S acyltransferase activity Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule. (more detail) 27 NA Homo sapiens

GOA IEI008211 Protein protein interactors of human gene MRPL42 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPL42 (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D TAX019782 GO:0019706 molecular function protein cysteine S palmitoyltransferase activity Catalysis of the transfer of a palmitoyl group to a sulfur atom on the cysteine of a protein molecul (more detail) 27 NA Homo sapiens

GOA TAX032441 GO:1902253 biological process regulation of intrinsic apoptotic signaling pathway by p53 class mediator Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by (more detail) 27 NA Homo sapiens

GOA IEI009746 Protein protein interactors of human gene PELO from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PELO (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D IEI002451 Protein protein interactors of human gene CHAF1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHAF1B (SwissProt ID (more detail) 27 17535438 Homo sapiens

I2D IEI007093 Protein protein interactors of human gene KSR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KSR1 (SwissProt ID=Q (more detail) 27 17535438 Homo sapiens

I2D TAX016966 GO:0007549 biological process dosage compensation Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sex (more detail) 16 NA Homo sapiens

GOA IEI014390 Protein protein interactors of human gene TSPYL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TSPYL2 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI009029 Protein protein interactors of human gene NR2E1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR2E1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI009942 Protein protein interactors of human gene PIM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIM2 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI014704 Protein protein interactors of human gene UNG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UNG (SwissProt ID=P1 (more detail) 16 17535438 Homo sapiens

I2D TAX017468 GO:0009048 biological process dosage compensation by inactivation of X chromosome Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global in (more detail) 16 NA Homo sapiens

GOA IEI012216 Protein protein interactors of human gene SIK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIK1 (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D IEI010943 Protein protein interactors of human gene RAD51C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD51C (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI014252 Protein protein interactors of human gene TRIM47 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM47 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI012036 Protein protein interactors of human gene SERPINB4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERPINB4 (SwissProt (more detail) 16 17535438 Homo sapiens

I2D IEI006599 Protein protein interactors of human gene JMJD1C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JMJD1C (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI011178 Protein protein interactors of human gene REPIN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene REPIN1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI002940 Protein protein interactors of human gene CPSF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CPSF4 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI009188 Protein protein interactors of human gene NUSAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUSAP1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI012812 Protein protein interactors of human gene SPAG8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPAG8 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI012615 Protein protein interactors of human gene SMG5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMG5 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI005817 Protein protein interactors of human gene HEY1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HEY1 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI003532 Protein protein interactors of human gene DHRS7B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHRS7B (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI015311 Protein protein interactors of human gene ZFP36L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZFP36L1 (SwissProt I (more detail) 16 17535438 Homo sapiens

I2D TAX034918 GO:2000773 biological process negative regulation of cellular senescence Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence. (more detail) 16 NA Homo sapiens

GOA TAX029341 GO:0071243 biological process cellular response to arsenic containing substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 16 NA Homo sapiens

GOA IEI006382 Protein protein interactors of human gene INA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INA (SwissProt ID=Q1 (more detail) 16 17535438 Homo sapiens

I2D IEI008960 Protein protein interactors of human gene NOTCH4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOTCH4 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX024443 GO:0043555 biological process regulation of translation in response to stress Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the (more detail) 16 NA Homo sapiens

GOA IEI009853 Protein protein interactors of human gene PHF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHF7 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D TAX022007 GO:0033158 biological process regulation of protein import into nucleus, translocation Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, (more detail) 16 NA Homo sapiens

GOA TAX025176 GO:0045623 biological process negative regulation of T helper cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differen (more detail) 16 NA Homo sapiens

GOA IEI014262 Protein protein interactors of human gene TRIM56 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM56 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX015313 GO:0004675 molecular function transmembrane receptor protein serine/threonine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to in (more detail) 16 NA Homo sapiens

GOA IEI002204 Protein protein interactors of human gene CDCA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDCA4 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D WIG000399 p53 Signaling Pathway p53 is a transcription factor who's activity is regulated by phosphorylation. The function is p53 is (more detail) 16 NA Homo sapiens

MSigDB WIG001144 Genes involved in Regulation of KIT signaling (more detail) 16 NA Homo sapiens

MSigDB WIG000675 Genes involved in Acyl chain remodelling of PG (more detail) 16 NA Homo sapiens

MSigDB TAX016389 GO:0006521 biological process regulation of cellular amino acid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 16 NA Homo sapiens

GOA MOX001892 Genes associated with Computational Drug Signature Isorhamnetin Genes associated with Computational Drug Signature Isorhamnetin, curated by the Drug Signature Datab (more detail) 16 25990557 Homo sapiens

DSigDB TAX000592 Genes annotated by the GO term GO:0009894. Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. (more detail) 16 NA Homo sapiens

MSigDB MOX013343 Genes associated with Computational Drug Signature L 741,626 Genes associated with Computational Drug Signature L-741,626, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB WAG000399 Cysteine metabolism (more detail) 16 NA Homo sapiens

KEGG MOX002562 Genes associated with Computational Drug Signature Fluazinam Genes associated with Computational Drug Signature Fluazinam, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB MOX000852 Genes associated with Computational Drug Signature benzo[a]pyrene 3,6 dione Genes associated with Computational Drug Signature benzo[a]pyrene-3,6-dione, curated by the Drug Sig (more detail) 16 25990557 Homo sapiens

DSigDB TAX014043 GO:0002070 biological process epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epit (more detail) 16 NA Homo sapiens

GOA MOX006933 Genes associated with Computational Drug Signature Altenusin Genes associated with Computational Drug Signature Altenusin, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB WAG001358 Synthesis of glycosylphosphatidylinositol (GPI) (more detail) 16 NA Homo sapiens

Reactome GEX001179 neural tube defects neural tube defects associated genes. PAGER constructed this gene set by grouping all genes which ar (more detail) 16 NA Homo sapiens

GAD MEX000353 Genes associated with Approved Drug mitomycin c Genes associated with Approved Drug mitomycin c, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB MOX003672 Genes associated with Computational Drug Signature amodiaquine Genes associated with Computational Drug Signature amodiaquine, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB MOX005520 Genes associated with Computational Drug Signature 172889 27 9 Genes associated with Computational Drug Signature 172889-27-9, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB MOX003413 Genes associated with Computational Drug Signature NVP AEW541 Genes associated with Computational Drug Signature NVP-AEW541, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens

DSigDB MEX000863 Genes associated with Approved Drug mycophenolic acid Genes associated with Approved Drug mycophenolic acid, curated by the Drug Signature Database (DSigD (more detail) 16 25990557 Homo sapiens

DSigDB TAX016068 GO:0006004 biological process fucose metabolic process The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers (more detail) 16 NA Homo sapiens

GOA IEI000977 Protein protein interactors of human gene ASGR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASGR1 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI013354 Protein protein interactors of human gene TAF6L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAF6L (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI004620 Protein protein interactors of human gene FBXL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXL2 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D TAX031683 GO:0140033 molecular function acetylation dependent protein binding Interacting selectively and non-covalently with a protein upon acetylation of the target protein. (more detail) 18 NA Homo sapiens

GOA IEI006888 Protein protein interactors of human gene KLF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF1 (SwissProt ID=Q (more detail) 18 17535438 Homo sapiens

I2D IEI012972 Protein protein interactors of human gene SRM from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRM (SwissProt ID=P1 (more detail) 18 17535438 Homo sapiens

I2D TAX027917 GO:0060444 biological process branching involved in mammary gland duct morphogenesis The process in which the branching structure of the mammary gland duct is generated and organized. T (more detail) 18 NA Homo sapiens

GOA TAX020392 GO:0030225 biological process macrophage differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of a macr (more detail) 18 NA Homo sapiens

GOA TAX024104 GO:0043011 biological process myeloid dendritic cell differentiation The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocomp (more detail) 18 NA Homo sapiens

GOA IEI013070 Protein protein interactors of human gene STAG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAG1 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI001323 Protein protein interactors of human gene BFAR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BFAR (SwissProt ID=Q (more detail) 18 17535438 Homo sapiens

I2D IEI006581 Protein protein interactors of human gene JAG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene JAG1 (SwissProt ID=P (more detail) 18 17535438 Homo sapiens

I2D IEI010479 Protein protein interactors of human gene PRKAR1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRKAR1B (SwissProt I (more detail) 18 17535438 Homo sapiens

I2D TAX026828 GO:0051145 biological process smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscl (more detail) 18 NA Homo sapiens

GOA TAX026809 GO:0051123 biological process RNA polymerase II transcriptional preinitiation complex assembly The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA t (more detail) 18 NA Homo sapiens

GOA TAX027626 GO:0060037 biological process pharyngeal system development The process whose specific outcome is the progression of the pharyngeal system over time, from its f (more detail) 18 NA Homo sapiens

GOA TAX029016 GO:0070577 molecular function lysine acetylated histone binding Interacting selectively and non-covalently with a histone in which a lysine residue has been modifie (more detail) 18 NA Homo sapiens

GOA TAX029247 GO:0071004 cellular component U2 type prespliceosome A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while (more detail) 18 NA Homo sapiens

GOA TAX021912 GO:0032986 biological process protein DNA complex disassembly The disaggregation of a protein-DNA complex into its constituent components. (more detail) 18 NA Homo sapiens

GOA TAX023284 GO:0036148 biological process phosphatidylglycerol acyl chain remodeling Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation (more detail) 18 NA Homo sapiens

GOA IEI001151 Protein protein interactors of human gene ATXN7L3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATXN7L3 (SwissProt I (more detail) 18 17535438 Homo sapiens

I2D IEI004154 Protein protein interactors of human gene ENC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ENC1 (SwissProt ID=O (more detail) 18 17535438 Homo sapiens

I2D MOX012577 Genes associated with Computational Drug Signature estradiol Genes associated with Computational Drug Signature estradiol, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB MOX001960 Genes associated with Computational Drug Signature Ginsenoside Re Genes associated with Computational Drug Signature Ginsenoside Re, curated by the Drug Signature Dat (more detail) 18 25990557 Homo sapiens

DSigDB WAG001470 transcription factor creb and its extracellular signals The transcription factor CREB binds the cyclic AMP response element (CRE) and activates transcriptio (more detail) 18 NA Homo sapiens

BioCarta MOX018096 Genes associated with Computational Drug Signature ZINC OXIDE Genes associated with Computational Drug Signature ZINC OXIDE, curated by the Drug Signature Databas (more detail) 18 25990557 Homo sapiens

DSigDB TAX000473 Genes annotated by the GO term GO:0042440. The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin. (more detail) 18 NA Homo sapiens

MSigDB MOX015097 Genes associated with Computational Drug Signature simvastatin Genes associated with Computational Drug Signature simvastatin, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens

DSigDB MOX015595 Genes associated with Computational Drug Signature tranilast Genes associated with Computational Drug Signature tranilast, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB MOX001864 Genes associated with Computational Drug Signature Mollugin Genes associated with Computational Drug Signature Mollugin, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB MOX003497 Genes associated with Computational Drug Signature Veliparib Genes associated with Computational Drug Signature Veliparib, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB TAX014161 GO:0002293 biological process alpha beta T cell differentiation involved in immune response The process in which an antigenically naive alpha-beta T cell acquires the specialized features of a (more detail) 18 NA Homo sapiens

GOA MOX004647 Genes associated with Computational Drug Signature selegiline Genes associated with Computational Drug Signature selegiline, curated by the Drug Signature Databas (more detail) 18 25990557 Homo sapiens

DSigDB MOX003682 Genes associated with Computational Drug Signature Anethole trithione Genes associated with Computational Drug Signature Anethole trithione, curated by the Drug Signature (more detail) 18 25990557 Homo sapiens

DSigDB MOX001255 Genes associated with Computational Drug Signature 76180 96 6 Genes associated with Computational Drug Signature 76180-96-6, curated by the Drug Signature Databas (more detail) 18 25990557 Homo sapiens

DSigDB MOX002636 Genes associated with Computational Drug Signature Rubitecan Genes associated with Computational Drug Signature Rubitecan, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB MOX006548 Genes associated with Computational Drug Signature AC1LEORR Genes associated with Computational Drug Signature AC1LEORR, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB MEX000573 Genes associated with Approved Drug budesonide Genes associated with Approved Drug budesonide, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB FOX000563 Genes in the cancer module 236 (more detail) 18 NA Homo sapiens

MSigDB TAX014158 GO:0002287 biological process alpha beta T cell activation involved in immune response The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, (more detail) 18 NA Homo sapiens

GOA WIG001196 Genes involved in Signaling by constitutively active EGFR (more detail) 18 NA Homo sapiens

MSigDB WIG001557 IL 2 Gene Expression in Activated and Quiescent T Cells IL-2 Gene Expression in Activated and Quiescent T-Cells (more detail) 18 NA Homo sapiens

Protein Lounge MOX007049 Genes associated with Computational Drug Signature apomorphine Genes associated with Computational Drug Signature apomorphine, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens

DSigDB MOX003386 Genes associated with Computational Drug Signature KU 55933 Genes associated with Computational Drug Signature KU-55933, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB WIG000413 PTEN dependent cell cycle arrest and apoptosis PTEN is a tumor suppressor gene. Recombinant PTEN is capable of dephosphorylating phosphatidylinosit (more detail) 18 NA Homo sapiens

MSigDB WIG001364 Doxorubicin Pathway (Cancer Cell), Pharmacodynamics Representation of the candidate genes involved in the action of doxorubicin in a stylized cancer cel (more detail) 18 NA Homo sapiens

PharmGKB TAX013300 GO:0000185 biological process activation of MAPKKK activity Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK). (more detail) 18 NA Homo sapiens

GOA MOX014695 Genes associated with Computational Drug Signature pyrimethamine Genes associated with Computational Drug Signature pyrimethamine, curated by the Drug Signature Data (more detail) 18 25990557 Homo sapiens

DSigDB MOX018079 Genes associated with Computational Drug Signature HARMINE Genes associated with Computational Drug Signature HARMINE, curated by the Drug Signature Database ( (more detail) 18 25990557 Homo sapiens

DSigDB IEI006133 Protein protein interactors of human gene IBTK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IBTK (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI010465 Protein protein interactors of human gene PRIM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRIM2 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI009979 Protein protein interactors of human gene PJA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PJA2 (SwissProt ID=O (more detail) 20 17535438 Homo sapiens

I2D IEI014977 Protein protein interactors of human gene WDCP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDCP (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI012576 Protein protein interactors of human gene SLX4IP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLX4IP (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI011107 Protein protein interactors of human gene RBMY1A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBMY1A1 (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D IEI004300 Protein protein interactors of human gene ESPL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ESPL1 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI002668 Protein protein interactors of human gene CLPB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLPB (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI011645 Protein protein interactors of human gene RRP9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RRP9 (SwissProt ID=O (more detail) 20 17535438 Homo sapiens

I2D WEX000099 TH2 Differentiation The genes related to th2 differentiation (adaptive immunity) in immune using next-generation sequenc (more detail) 20 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI006293 Protein protein interactors of human gene IL12A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL12A (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D TAX026867 GO:0051197 biological process positive regulation of coenzyme metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 20 NA Homo sapiens

GOA TAX025197 GO:0045649 biological process regulation of macrophage differentiation Any process that modulates the frequency, rate or extent of macrophage differentiation. (more detail) 20 NA Homo sapiens

GOA TAX019027 GO:0016441 biological process posttranscriptional gene silencing The inactivation of gene expression by a posttranscriptional mechanism. (more detail) 20 NA Homo sapiens

GOA IEI009085 Protein protein interactors of human gene NSMCE2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NSMCE2 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI007760 Protein protein interactors of human gene MBD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MBD4 (SwissProt ID=O (more detail) 20 17535438 Homo sapiens

I2D IEI006638 Protein protein interactors of human gene KATNA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KATNA1 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D TAX020980 GO:0031418 molecular function L ascorbic acid binding Interacting selectively and non-covalently with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4- (more detail) 20 NA Homo sapiens

GOA TAX020652 GO:0030813 biological process positive regulation of nucleotide catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 20 NA Homo sapiens

GOA TAX032259 GO:1901798 biological process positive regulation of signal transduction by p53 class mediator Any process that activates or increases the frequency, rate or extent of signal transduction by p53 (more detail) 20 NA Homo sapiens

GOA IEI003353 Protein protein interactors of human gene DCK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCK (SwissProt ID=P2 (more detail) 20 17535438 Homo sapiens

I2D IEI004609 Protein protein interactors of human gene FBP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBP2 (SwissProt ID=O (more detail) 20 17535438 Homo sapiens

I2D MOX004286 Genes associated with Computational Drug Signature maprotiline Genes associated with Computational Drug Signature maprotiline, curated by the Drug Signature Databa (more detail) 20 25990557 Homo sapiens

DSigDB MAX000644 The lung adenocarcinoma TSP (tumor sequencing project) genes mutations in which show positive correlation with the higher overall mutation rate. Determining the genetic basis of cancer requires comprehensive analyses of large collections of hist (more detail) 20 NA Homo sapiens

MSigDB MOX003047 Genes associated with Computational Drug Signature Dutasteride Genes associated with Computational Drug Signature Dutasteride, curated by the Drug Signature Databa (more detail) 20 25990557 Homo sapiens

DSigDB MOX000395 Genes associated with Computational Drug Signature Nobiletin Genes associated with Computational Drug Signature Nobiletin, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB FEX002198 Lymphoma Qiu03 42genes Table 1 General ALL markers; A total of 39 genes among which four were unknown were expressed in e (more detail) 20 12970791 Homo sapiens

GeneSigDB MOX001370 Genes associated with Computational Drug Signature 13 Cis retinal Genes associated with Computational Drug Signature 13-Cis retinal, curated by the Drug Signature Dat (more detail) 20 25990557 Homo sapiens

DSigDB WAG000400 Lysine biosynthesis (more detail) 20 NA Homo sapiens

KEGG MOX005160 Genes associated with Computational Drug Signature Lopinavir Genes associated with Computational Drug Signature Lopinavir, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB WAG000046 Signaling events mediated by PRL (more detail) 20 NA Homo sapiens

NCI-Nature Curated MOX005065 Genes associated with Computational Drug Signature riluzole Genes associated with Computational Drug Signature riluzole, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB TAX000618 Genes annotated by the GO term GO:0006275. Any process that modulates the frequency, rate or extent of DNA replication. (more detail) 20 NA Homo sapiens

MSigDB FEX001327 Leukemia Neben05 22genes Table 2. Differentially expressed genes in AML samples with FLT3-LM (n=36) FLT3-LM (n=20) and NRAS (more detail) 20 15674343 Homo sapiens

GeneSigDB FEX002373 MesenchymalStemCells Boeuf08 23genes Table 4. Genes down-regulated during chondrogenic differentiation of MSC spheroids; Mean expression (more detail) 20 18702172 Homo sapiens

GeneSigDB PEX000530 Sushi: Sushi repeat (SCR repeat) (more detail) 20 NA Homo sapiens

Pfam WAG001023 nf kb signaling pathway Nuclear factor kB (NF-kB) is a nuclear transcription factor that regulates expression of a large num (more detail) 20 NA Homo sapiens

BioCarta MAX001956 Genes involved in glycolysis; based on literature and sequence annotation resources and converted to Affymetrix HG U133A probe sets. DNA microarrays can be used to identify gene expression changes characteristic of human disease. Thi (more detail) 20 NA Homo sapiens

MSigDB MOX002973 Genes associated with Computational Drug Signature Goniothalamin Genes associated with Computational Drug Signature Goniothalamin, curated by the Drug Signature Data (more detail) 20 25990557 Homo sapiens

DSigDB TAX000229 Genes annotated by the GO term GO:0048732. The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. (more detail) 13 NA Homo sapiens

MSigDB TAX013488 GO:0000783 cellular component nuclear telomere cap complex A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects (more detail) 13 NA Homo sapiens

GOA MOX012422 Genes associated with Computational Drug Signature dopamine Genes associated with Computational Drug Signature dopamine, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens

DSigDB TAX001395 Genes annotated by the GO term GO:0003707. Combining with a steroid hormone to initiate a change in cell activity. (more detail) 13 NA Homo sapiens

MSigDB TAX013487 GO:0000782 cellular component telomere cap complex A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes (more detail) 13 NA Homo sapiens

GOA TAX013294 GO:0000177 cellular component cytoplasmic exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity pr (more detail) 13 NA Homo sapiens

GOA WAG001011 p53 signaling pathway p53 is a transcription factor who's activity is regulated by phosphorylation. The function is p53 is (more detail) 13 NA Homo sapiens

BioCarta TAX000359 Genes annotated by the GO term GO:0006376. Selection of a splice site by components of the assembling spliceosome. (more detail) 13 NA Homo sapiens

MSigDB MOX002107 Genes associated with Computational Drug Signature O,P' DDE Genes associated with Computational Drug Signature O,P'-DDE, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens

DSigDB MOX013132 Genes associated with Computational Drug Signature Indatraline hydrochloride Genes associated with Computational Drug Signature Indatraline hydrochloride, curated by the Drug Si (more detail) 13 25990557 Homo sapiens

DSigDB TAX013868 GO:0001829 biological process trophectodermal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a trophect (more detail) 13 NA Homo sapiens

GOA MOX000126 Genes associated with Computational Drug Signature 2 Phenylphenol Genes associated with Computational Drug Signature 2-Phenylphenol, curated by the Drug Signature Dat (more detail) 13 25990557 Homo sapiens

DSigDB MOX002247 Genes associated with Computational Drug Signature DENSPM Genes associated with Computational Drug Signature DENSPM, curated by the Drug Signature Database (D (more detail) 13 25990557 Homo sapiens

DSigDB TAX013532 GO:0000900 molecular function translation repressor activity, mRNA regulatory element binding Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through (more detail) 13 NA Homo sapiens

GOA TAX013376 GO:0000346 cellular component transcription export complex The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRN (more detail) 13 NA Homo sapiens

GOA FEX003379 Viral Ruutu02 16genes Table I ? Upregulated Genes in all Passages of UT-DEC-1 (an HPV-33-positive cell line) Compared to C (more detail) 13 12115547 Homo sapiens

GeneSigDB WIG000931 Genes involved in Initial triggering of complement (more detail) 13 NA Homo sapiens

MSigDB MEX003656 Genes associated with Perturbagen Signature moroxydine Genes associated with Perturbagen Signature moroxydine, curated by the Drug Signature Database (DSig (more detail) 13 25990557 Homo sapiens

DSigDB TAX000221 Genes annotated by the GO term GO:0000080. Progression through G1 phase, one of two 'gap' phases in the mitotic cell cycle; G1 is the interval between the completion of mitosis and the beginning of DNA synthesis. (more detail) 13 NA Homo sapiens

MSigDB WIG000422 RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage Cell cycle checkpoint controls at the G1 to S transition and the G2 to M transition prevent the cell (more detail) 13 NA Homo sapiens

MSigDB FEX002183 Lymphoma Kari03 25genes Table S3a.Signature Membership Unique Genes: ARHB Signature Genes (more detail) 13 12782714 Homo sapiens

GeneSigDB WIG000258 Oxidative Stress Induced Gene Expression Via Nrf2 Reactive oxygen species (ROS) can damage biological macromolecules and are detrimental to cellular h (more detail) 13 NA Homo sapiens

MSigDB FOX000752 Genes in the cancer module 474 (more detail) 13 NA Homo sapiens

MSigDB IEI003852 Protein protein interactors of human gene DUSP6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP6 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI006907 Protein protein interactors of human gene KLHDC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHDC3 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI014580 Protein protein interactors of human gene UBE2J2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2J2 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI001426 Protein protein interactors of human gene BRD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRD3 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D TAX019106 GO:0016580 cellular component Sin3 complex A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor (more detail) 13 NA Homo sapiens

GOA TAX032683 GO:1902894 biological process negative regulation of pri miRNA transcription by RNA polymerase II Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription (more detail) 13 NA Homo sapiens

GOA IEI015264 Protein protein interactors of human gene ZCCHC7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZCCHC7 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI004254 Protein protein interactors of human gene ERCC6L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERCC6L (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI000556 Protein protein interactors of human gene ANAPC13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC13 (SwissProt I (more detail) 13 17535438 Homo sapiens

I2D IEI014409 Protein protein interactors of human gene TTC14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTC14 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX019251 GO:0016840 molecular function carbon nitrogen lyase activity Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond o (more detail) 13 NA Homo sapiens

GOA TAX033554 GO:1904668 biological process positive regulation of ubiquitin protein ligase activity Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase ac (more detail) 13 NA Homo sapiens

GOA IEI009103 Protein protein interactors of human gene NT5DC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NT5DC2 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI001461 Protein protein interactors of human gene BTAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BTAF1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX017659 GO:0009313 biological process oligosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with b (more detail) 13 NA Homo sapiens

GOA TAX034592 GO:2000303 biological process regulation of ceramide biosynthetic process Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process. (more detail) 13 NA Homo sapiens

GOA IEI008937 Protein protein interactors of human gene NOM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOM1 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI004298 Protein protein interactors of human gene ESF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ESF1 (SwissProt ID=Q (more detail) 13 17535438 Homo sapiens

I2D IEI005982 Protein protein interactors of human gene HOXC11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXC11 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI000968 Protein protein interactors of human gene ASCC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASCC1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX023156 GO:0035925 molecular function mRNA 3' UTR AU rich region binding Interacting selectively and non-covalently with a region containing frequent adenine and uridine bas (more detail) 13 NA Homo sapiens

GOA TAX020623 GO:0030686 cellular component 90S preribosome A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisi (more detail) 13 NA Homo sapiens

GOA IEI010345 Protein protein interactors of human gene PPP1R13L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R13L (SwissProt (more detail) 13 17535438 Homo sapiens

I2D IEI004296 Protein protein interactors of human gene ESCO2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ESCO2 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI004904 Protein protein interactors of human gene FRK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FRK (SwissProt ID=P4 (more detail) 13 17535438 Homo sapiens

I2D IEI013635 Protein protein interactors of human gene TGFBRAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TGFBRAP1 (SwissProt (more detail) 13 17535438 Homo sapiens

I2D IEI014250 Protein protein interactors of human gene TRIM45 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM45 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI001020 Protein protein interactors of human gene ATF6B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATF6B (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX030363 GO:0090153 biological process regulation of sphingolipid biosynthetic process Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid (more detail) 13 NA Homo sapiens

GOA TAX024004 GO:0042761 biological process very long chain fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid which has a chain len (more detail) 13 NA Homo sapiens

GOA IEI006205 Protein protein interactors of human gene IFRD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFRD2 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI013394 Protein protein interactors of human gene TASOR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TASOR (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI014275 Protein protein interactors of human gene TRIM74 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM74 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI000978 Protein protein interactors of human gene ASGR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASGR2 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX017856 GO:0010092 biological process specification of animal organ identity The regionalization process in which the identity of an animal organ primordium is specified. Identi (more detail) 13 NA Homo sapiens

GOA TAX030744 GO:0097200 molecular function cysteine type endopeptidase activity involved in execution phase of apoptosis Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism i (more detail) 13 NA Homo sapiens

GOA IEI011356 Protein protein interactors of human gene RMND5B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RMND5B (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D TAX021810 GO:0032823 biological process regulation of natural killer cell differentiation Any process that modulates the frequency, rate or extent of natural killer cell differentiation. (more detail) 13 NA Homo sapiens

GOA IEI009019 Protein protein interactors of human gene NR1D1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NR1D1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI010585 Protein protein interactors of human gene PRSS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRSS3 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI003982 Protein protein interactors of human gene EFNA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFNA5 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D IEI012666 Protein protein interactors of human gene SNAPC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNAPC1 (SwissProt ID (more detail) 13 17535438 Homo sapiens

I2D IEI006483 Protein protein interactors of human gene IRF2BP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IRF2BP1 (SwissProt I (more detail) 13 17535438 Homo sapiens

I2D IEI013609 Protein protein interactors of human gene TFDP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TFDP2 (SwissProt ID= (more detail) 13 17535438 Homo sapiens

I2D TAX033756 GO:1905038 biological process regulation of membrane lipid metabolic process Any process that modulates the frequency, rate or extent of membrane lipid metabolic process. (more detail) 13 NA Homo sapiens

GOA IEI005800 Protein protein interactors of human gene HERC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HERC4 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI002428 Protein protein interactors of human gene CFH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CFH (SwissProt ID=P0 (more detail) 22 17535438 Homo sapiens

I2D IEI007501 Protein protein interactors of human gene LUC7L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LUC7L (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI014056 Protein protein interactors of human gene TNPO2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNPO2 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI011328 Protein protein interactors of human gene RIOK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RIOK3 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI008459 Protein protein interactors of human gene MYLK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYLK2 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI008248 Protein protein interactors of human gene MRPS31 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MRPS31 (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D IEI005851 Protein protein interactors of human gene HIPK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HIPK1 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI002040 Protein protein interactors of human gene CCND2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCND2 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI012938 Protein protein interactors of human gene SPTBN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPTBN2 (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D IEI010506 Protein protein interactors of human gene PRLR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRLR (SwissProt ID=P (more detail) 22 17535438 Homo sapiens

I2D TAX025305 GO:0045841 biological process negative regulation of mitotic metaphase/anaphase transition Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process (more detail) 22 NA Homo sapiens

GOA TAX022936 GO:0035561 biological process regulation of chromatin binding Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is (more detail) 22 NA Homo sapiens

GOA IEI007831 Protein protein interactors of human gene MEAF6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MEAF6 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI004027 Protein protein interactors of human gene EIF2AK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF2AK4 (SwissProt I (more detail) 22 17535438 Homo sapiens

I2D IEI013537 Protein protein interactors of human gene TEAD3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TEAD3 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI004282 Protein protein interactors of human gene ERO1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ERO1A (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI011408 Protein protein interactors of human gene RNF167 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF167 (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D IEI012175 Protein protein interactors of human gene SHC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SHC3 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI006731 Protein protein interactors of human gene KCTD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KCTD1 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI008393 Protein protein interactors of human gene MUTYH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MUTYH (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI002739 Protein protein interactors of human gene CNOT9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNOT9 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D IEI013674 Protein protein interactors of human gene THOC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THOC3 (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D TAX022047 GO:0033233 biological process regulation of protein sumoylation Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein (more detail) 22 NA Homo sapiens

GOA TAX023148 GO:0035909 biological process aorta morphogenesis The process in which the anatomical structures of an aorta are generated and organized. An aorta is (more detail) 22 NA Homo sapiens

GOA IEI002740 Protein protein interactors of human gene CNP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNP (SwissProt ID=P0 (more detail) 22 17535438 Homo sapiens

I2D IEI009462 Protein protein interactors of human gene PAK6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAK6 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens

I2D IEI003687 Protein protein interactors of human gene DNAJC9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJC9 (SwissProt ID (more detail) 22 17535438 Homo sapiens

I2D IEI006620 Protein protein interactors of human gene KALRN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KALRN (SwissProt ID= (more detail) 22 17535438 Homo sapiens

I2D WAG000215 regulation of bad phosphorylation The function of the pro-apoptotic molecule BAD is regulated by phosphorylation of three sites (ser 1 (more detail) 22 NA Homo sapiens

BioCarta FEX000054 Bone Ohali04 23genes Table 2. Selected down-regulated genes in the microarray-based poor prognosis signature ES patients (more detail) 22 15467746 Homo sapiens

GeneSigDB MOX016135 Genes associated with Computational Drug Signature DEOXYCHOLIC ACID Genes associated with Computational Drug Signature DEOXYCHOLIC ACID, curated by the Drug Signature D (more detail) 22 25990557 Homo sapiens

DSigDB MOX004788 Genes associated with Computational Drug Signature triamcinolone Genes associated with Computational Drug Signature triamcinolone, curated by the Drug Signature Data (more detail) 22 25990557 Homo sapiens

DSigDB WIG000289 Apoptotic Signaling in Response to DNA Damage The cellular activation of the caspase cascade resulting in cell death is triggered by chemical dama (more detail) 22 NA Homo sapiens

MSigDB FAX000181 Targets of MicroRNA TACGGGT,MIR 99A,MIR 100,MIR 99B (more detail) 22 NA Homo sapiens

MSigDB TAX000968 Genes annotated by the GO term GO:0005761. A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. (more detail) 22 NA Homo sapiens

MSigDB TAX014140 GO:0002262 biological process myeloid cell homeostasis The process of regulating the proliferation and elimination of myeloid cells such that the total num (more detail) 22 NA Homo sapiens

GOA MOX000542 Genes associated with Computational Drug Signature Amentoflavone Genes associated with Computational Drug Signature Amentoflavone, curated by the Drug Signature Data (more detail) 22 25990557 Homo sapiens

DSigDB MEX000186 Genes associated with Approved Drug leflunomide Genes associated with Approved Drug leflunomide, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens

DSigDB TAX000999 Genes annotated by the GO term GO:0000313. A ribosome contained within a subcellular organelle. (more detail) 22 NA Homo sapiens

MSigDB MOX013718 Genes associated with Computational Drug Signature mifepristone Genes associated with Computational Drug Signature mifepristone, curated by the Drug Signature Datab (more detail) 22 25990557 Homo sapiens

DSigDB FEX000129 Brain Watson02 24genes Table 2. GenBank Accession Number Gene Name and Reported Chromosomal Localization of Gene Transcri (more detail) 22 12163391 Homo sapiens

GeneSigDB MOX003995 Genes associated with Computational Drug Signature dimethoate Genes associated with Computational Drug Signature dimethoate, curated by the Drug Signature Databas (more detail) 22 25990557 Homo sapiens

DSigDB IEI007198 Protein protein interactors of human gene LDHAL6B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LDHAL6B (SwissProt I (more detail) 24 17535438 Homo sapiens

I2D IEI006180 Protein protein interactors of human gene IFIT5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFIT5 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI009186 Protein protein interactors of human gene NUPR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUPR1 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI000959 Protein protein interactors of human gene ASB18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASB18 (SwissProt ID= (more detail) 24 17535438 Homo sapiens

I2D IEI005724 Protein protein interactors of human gene HBB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HBB (SwissProt ID=P6 (more detail) 24 17535438 Homo sapiens

I2D IEI009686 Protein protein interactors of human gene PDGFRL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDGFRL (SwissProt ID (more detail) 24 17535438 Homo sapiens

I2D TAX018416 GO:0014888 biological process striated muscle adaptation Any process in which striated muscle adapts, with consequent modifications to structural and/or func (more detail) 24 NA Homo sapiens

GOA TAX025110 GO:0045446 biological process endothelial cell differentiation The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of (more detail) 24 NA Homo sapiens

GOA MOX001835 Genes associated with Computational Drug Signature leflunomide Genes associated with Computational Drug Signature leflunomide, curated by the Drug Signature Databa (more detail) 24 25990557 Homo sapiens

DSigDB MOX003046 Genes associated with Computational Drug Signature Fludioxonil Genes associated with Computational Drug Signature Fludioxonil, curated by the Drug Signature Databa (more detail) 24 25990557 Homo sapiens

DSigDB MOX004148 Genes associated with Computational Drug Signature nitroglycerin Genes associated with Computational Drug Signature nitroglycerin, curated by the Drug Signature Data (more detail) 24 25990557 Homo sapiens

DSigDB MOX018101 Genes associated with Computational Drug Signature rolipram Genes associated with Computational Drug Signature rolipram, curated by the Drug Signature Database (more detail) 24 25990557 Homo sapiens

DSigDB TAX000066 Genes annotated by the GO term GO:0016052. The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. (more detail) 24 NA Homo sapiens

MSigDB WAG001072 Plasma membrane estrogen receptor signaling (more detail) 24 NA Homo sapiens

NCI-Nature Curated MOX003115 Genes associated with Computational Drug Signature enoxolone Genes associated with Computational Drug Signature enoxolone, curated by the Drug Signature Database (more detail) 24 25990557 Homo sapiens

DSigDB MOX012888 Genes associated with Computational Drug Signature GNF PF 2893 Genes associated with Computational Drug Signature GNF-PF-2893, curated by the Drug Signature Databa (more detail) 24 25990557 Homo sapiens

DSigDB MOX012891 Genes associated with Computational Drug Signature GNF Pf 3464 Genes associated with Computational Drug Signature GNF-Pf-3464, curated by the Drug Signature Databa (more detail) 24 25990557 Homo sapiens

DSigDB MOX004865 Genes associated with Computational Drug Signature 2 Acetamidofluorene Genes associated with Computational Drug Signature 2-Acetamidofluorene, curated by the Drug Signatur (more detail) 24 25990557 Homo sapiens

DSigDB WIG001335 Fluoropyrimidine Pathway, Pharmacokinetics Representation of the metabolic pathways for fluoropyrimidines. (more detail) 24 NA Homo sapiens

PharmGKB MOX005801 Genes associated with Computational Drug Signature 3,4 dichloroisocoumarin Genes associated with Computational Drug Signature 3,4-dichloroisocoumarin, curated by the Drug Sign (more detail) 24 25990557 Homo sapiens

DSigDB MOX004432 Genes associated with Computational Drug Signature norethindrone Genes associated with Computational Drug Signature norethindrone, curated by the Drug Signature Data (more detail) 24 25990557 Homo sapiens

DSigDB MOX004085 Genes associated with Computational Drug Signature fenbendazole Genes associated with Computational Drug Signature fenbendazole, curated by the Drug Signature Datab (more detail) 24 25990557 Homo sapiens

DSigDB TAX000463 Genes annotated by the GO term GO:0046489. The chemical reactions and pathways resulting in the formation of phosphoinositides, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of inositol. (more detail) 24 NA Homo sapiens

MSigDB FEX001206 Kidney Takahashi03 30genes papillary Table 2. Relatively more highly expressed genes in papillary RCC. (more detail) 24 14555994 Homo sapiens

GeneSigDB WAG001461 skeletal muscle hypertrophy is regulated via akt mtor pathway Skeletal muscle atrophies with disuse while with increased use and increased load skeletal muscle ex (more detail) 24 NA Homo sapiens

BioCarta WIG000786 Genes involved in DARPP 32 events (more detail) 24 NA Homo sapiens

MSigDB MOX003029 Genes associated with Computational Drug Signature Everolimus Genes associated with Computational Drug Signature Everolimus, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens

DSigDB WIG000401 Role of Parkin in the Ubiquitin Proteasomal Pathway The motor defects of Parkinson's disease are related to the loss of dopaminergic neurons in specific (more detail) 10 NA Homo sapiens

MSigDB TAX001239 Genes annotated by the GO term GO:0000030. Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid. (more detail) 10 NA Homo sapiens

MSigDB WIG000813 Genes involved in E2F enabled inhibition of pre replication complex formation (more detail) 10 NA Homo sapiens

MSigDB WIG000951 Genes involved in IRAK1 recruits IKK complex (more detail) 10 NA Homo sapiens

MSigDB TAX000608 Genes annotated by the GO term GO:0033044. Any process that modulates the frequency, rate or extent of the processes involved in the formation, arrangement of constituent parts, or disassembly of a chromosome. (more detail) 10 NA Homo sapiens

MSigDB MEX001630 Genes associated with Kinase Inhibitor Kinome 2812 Genes associated with Kinase Inhibitor Kinome_2812, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MOX000561 Genes associated with Computational Drug Signature CICLOPIROX Genes associated with Computational Drug Signature CICLOPIROX, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB MOX013046 Genes associated with Computational Drug Signature hydrocortisone Genes associated with Computational Drug Signature hydrocortisone, curated by the Drug Signature Dat (more detail) 10 25990557 Homo sapiens

DSigDB MOX013102 Genes associated with Computational Drug Signature IK 682 Genes associated with Computational Drug Signature IK-682, curated by the Drug Signature Database (D (more detail) 10 25990557 Homo sapiens

DSigDB MOX012803 Genes associated with Computational Drug Signature gamma Imino ATP Genes associated with Computational Drug Signature gamma-Imino-ATP, curated by the Drug Signature Da (more detail) 10 25990557 Homo sapiens

DSigDB TAX016295 GO:0006390 biological process mitochondrial transcription The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA poly (more detail) 10 NA Homo sapiens

GOA TAX025050 GO:0045292 biological process mRNA cis splicing, via spliceosome The joining together, after removal of an intervening sequence composed of one or more introns, of t (more detail) 10 NA Homo sapiens

GOA TAX025440 GO:0046087 biological process cytidine metabolic process The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucl (more detail) 10 NA Homo sapiens

GOA TAX025496 GO:0046218 biological process indolalkylamine catabolic process The chemical reactions and pathways resulting in the breakdown of indolalkylamines, indole or indole (more detail) 10 NA Homo sapiens

GOA TAX028786 GO:0070189 biological process kynurenine metabolic process The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine. (more detail) 10 NA Homo sapiens

GOA IEI003155 Protein protein interactors of human gene CUEDC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CUEDC1 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI001568 Protein protein interactors of human gene C1S from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C1S (SwissProt ID=P0 (more detail) 10 17535438 Homo sapiens

I2D WAG000028 the prc2 complex sets long term gene silencing through modification of histone tails Packaging of D into chromatin allows the cell to store its genetic information efficiently and has a (more detail) 10 NA Homo sapiens

BioCarta WIG000627 Taurine and hypotaurine metabolism (more detail) 10 NA Homo sapiens

MSigDB TAX000228 Genes annotated by the GO term GO:0016458. Any mechanism, at the level of transcription or post transcription, causing long term gene inactivation. (more detail) 10 NA Homo sapiens

MSigDB TAX000574 Genes annotated by the GO term GO:0006163. The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5' hydroxyl group of its glycose moiety. (more detail) 10 NA Homo sapiens

MSigDB WIG000670 Genes involved in Activation of the AP 1 family of transcription factors (more detail) 10 NA Homo sapiens

MSigDB WIG001122 Genes involved in RAF/MAP kinase cascade (more detail) 10 NA Homo sapiens

MSigDB WIG001046 Genes involved in Opsins (more detail) 10 NA Homo sapiens

MSigDB WIG001362 Fluoropyrimidine Pathway, Pharmacodynamics Model non-tissue-specific cancer cell displaying genes which may be involved in the pharmacodynamics (more detail) 10 NA Homo sapiens

PharmGKB MOX000174 Genes associated with Computational Drug Signature Harman Genes associated with Computational Drug Signature Harman, curated by the Drug Signature Database (D (more detail) 10 25990557 Homo sapiens

DSigDB MOX002143 Genes associated with Computational Drug Signature Theaflavin Genes associated with Computational Drug Signature Theaflavin, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB TAX021318 GO:0032070 biological process regulation of deoxyribonuclease activity Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolys (more detail) 10 NA Homo sapiens

GOA TAX016437 GO:0006570 biological process tyrosine metabolic process The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxy (more detail) 10 NA Homo sapiens

GOA TAX016197 GO:0006222 biological process UMP biosynthetic process The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate. (more detail) 10 NA Homo sapiens

GOA TAX017569 GO:0009174 biological process pyrimidine ribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophos (more detail) 10 NA Homo sapiens

GOA TAX030815 GO:0097354 biological process prenylation The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups (more detail) 10 NA Homo sapiens

GOA TAX029184 GO:0070914 biological process UV damage excision repair A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision i (more detail) 10 NA Homo sapiens

GOA TAX017487 GO:0009071 biological process serine family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, (more detail) 10 NA Homo sapiens

GOA TAX025403 GO:0046033 biological process AMP metabolic process The chemical reactions and pathways involving AMP, adenosine monophosphate. (more detail) 10 NA Homo sapiens

GOA TAX027064 GO:0051567 biological process histone H3 K9 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of t (more detail) 10 NA Homo sapiens

GOA TAX020619 GO:0030681 cellular component multimeric ribonuclease P complex A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules (more detail) 10 NA Homo sapiens

GOA TAX013894 GO:0001867 biological process complement activation, lectin pathway Any process involved in the activation of any of the steps of the lectin pathway of the complement c (more detail) 10 NA Homo sapiens

GOA PEX001072 FKBP C: FKBP type peptidyl prolyl cis trans isomerase (more detail) 10 NA Homo sapiens

Pfam IEI015015 Protein protein interactors of human gene WDR5B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR5B (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI003850 Protein protein interactors of human gene DUSP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP4 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI004196 Protein protein interactors of human gene EPB41L5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPB41L5 (SwissProt I (more detail) 10 17535438 Homo sapiens

I2D TAX023825 GO:0042416 biological process dopamine biosynthetic process The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotra (more detail) 10 NA Homo sapiens

GOA TAX023834 GO:0042428 biological process serotonin metabolic process The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotran (more detail) 10 NA Homo sapiens

GOA WIG000430 E2F1 Destruction Pathway E2F-1 is a transcription factor that regulates the expression of genes involved in the cell cycle an (more detail) 10 NA Homo sapiens

MSigDB MAX000416 List of the transcription factors up regulated 1 hr after wounding HDF cells (dermal fibroblasts). P27kip is a key inhibitory protein of the cell-cycle progression, which is rapidly downregulated in (more detail) 10 NA Homo sapiens

MSigDB MEX001900 Genes associated with Kinase Inhibitor BMS 345541 free base Genes associated with Kinase Inhibitor BMS-345541 free base, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB MEX002245 Genes associated with Kinase Inhibitor Kinome 192 Genes associated with Kinase Inhibitor Kinome_192, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MOX003525 Genes associated with Computational Drug Signature Navitoclax Genes associated with Computational Drug Signature Navitoclax, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB MOX003328 Genes associated with Computational Drug Signature Procyanidin B2 Genes associated with Computational Drug Signature Procyanidin B2, curated by the Drug Signature Dat (more detail) 10 25990557 Homo sapiens

DSigDB MOX001178 Genes associated with Computational Drug Signature DIHEXYL PHTHALATE Genes associated with Computational Drug Signature DIHEXYL PHTHALATE, curated by the Drug Signature (more detail) 10 25990557 Homo sapiens

DSigDB MOX001874 Genes associated with Computational Drug Signature ropinirole Genes associated with Computational Drug Signature ropinirole, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB MOX002387 Genes associated with Computational Drug Signature Malvidin Genes associated with Computational Drug Signature Malvidin, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB TAX021476 GO:0032356 molecular function oxidized DNA binding Interacting selectively and non-covalently with oxidized residues in DNA. (more detail) 10 NA Homo sapiens

GOA TAX022481 GO:0034427 biological process nuclear transcribed mRNA catabolic process, exonucleolytic, 3' 5' The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occu (more detail) 10 NA Homo sapiens

GOA TAX016200 GO:0006228 biological process UTP biosynthetic process The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate. (more detail) 10 NA Homo sapiens

GOA TAX016230 GO:0006285 biological process base excision repair, AP site formation The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recog (more detail) 10 NA Homo sapiens

GOA TAX016248 GO:0006307 biological process DNA dealkylation involved in DNA repair The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine b (more detail) 10 NA Homo sapiens

GOA TAX030619 GO:0090735 biological process DNA repair complex assembly The aggregation, arrangement and bonding together of a set of components to form a DNA repair comple (more detail) 10 NA Homo sapiens

GOA TAX031099 GO:0098734 biological process macromolecule depalmitoylation The removal of palymitoyl groups from a macromolecule. (more detail) 10 NA Homo sapiens

GOA TAX013470 GO:0000730 biological process DNA recombinase assembly The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into hi (more detail) 10 NA Homo sapiens

GOA TAX019681 GO:0019336 biological process phenol containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing (more detail) 10 NA Homo sapiens

GOA TAX018787 GO:0015924 molecular function mannosyl oligosaccharide mannosidase activity Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharid (more detail) 10 NA Homo sapiens

GOA TAX023964 GO:0042693 biological process muscle cell fate commitment The process in which the cellular identity of muscle cells is acquired and determined. (more detail) 10 NA Homo sapiens

GOA TAX019288 GO:0016892 molecular function endoribonuclease activity, producing 3' phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks t (more detail) 10 NA Homo sapiens

GOA TAX025548 GO:0046385 biological process deoxyribose phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phospho (more detail) 10 NA Homo sapiens

GOA TAX020835 GO:0031126 biological process snoRNA 3' end processing Any process involved in forming the mature 3' end of a snoRNA molecule. (more detail) 10 NA Homo sapiens

GOA MOX015964 Genes associated with Computational Drug Signature ZM 336372 Genes associated with Computational Drug Signature ZM 336372, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB FEX010709 hsa miR 518a 3p HITS-CLIP, Functional MTI (Weak) (more detail) 10 NA Homo sapiens

mirTARbase IEI015871 Protein protein interactors of human gene ZYG11B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZYG11B (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI004634 Protein protein interactors of human gene FBXO17 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO17 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI012607 Protein protein interactors of human gene SMC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMC6 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI014249 Protein protein interactors of human gene TRIM44 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM44 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D MEX002193 Genes associated with Kinase Inhibitor Kinome 1218 Genes associated with Kinase Inhibitor Kinome_1218, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MOX001741 Genes associated with Computational Drug Signature DIISODECYL PHTHALATE Genes associated with Computational Drug Signature DIISODECYL PHTHALATE, curated by the Drug Signatu (more detail) 10 25990557 Homo sapiens

DSigDB MOX008993 Genes associated with Computational Drug Signature CHEMBL230686 Genes associated with Computational Drug Signature CHEMBL230686, curated by the Drug Signature Datab (more detail) 10 25990557 Homo sapiens

DSigDB TAX021793 GO:0032802 biological process low density lipoprotein particle receptor catabolic process The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle (more detail) 10 NA Homo sapiens

GOA TAX022681 GO:0034982 biological process mitochondrial protein processing The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import. (more detail) 10 NA Homo sapiens

GOA TAX017642 GO:0009265 biological process 2' deoxyribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compou (more detail) 10 NA Homo sapiens

GOA TAX017823 GO:0009972 biological process cytidine deamination The removal of amino group in the presence of water. (more detail) 10 NA Homo sapiens

GOA TAX024077 GO:0042975 molecular function peroxisome proliferator activated receptor binding Interacting selectively and non-covalently with any of the peroxisome proliferator activated recepto (more detail) 10 NA Homo sapiens

GOA TAX019522 GO:0018342 biological process protein prenylation The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups (more detail) 10 NA Homo sapiens

GOA TAX027223 GO:0051864 molecular function histone demethylase activity (H3 K36 specific) Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = (more detail) 10 NA Homo sapiens

GOA TAX025608 GO:0046501 biological process protoporphyrinogen IX metabolic process The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the (more detail) 10 NA Homo sapiens

GOA TAX015203 GO:0004526 molecular function ribonuclease P activity Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor. (more detail) 10 NA Homo sapiens

GOA TAX034824 GO:2000628 biological process regulation of miRNA metabolic process Any process that modulates the frequency, rate or extent of miRNA metabolic process. (more detail) 10 NA Homo sapiens

GOA TAX032698 GO:1902916 biological process positive regulation of protein polyubiquitination Any process that activates or increases the frequency, rate or extent of protein polyubiquitination. (more detail) 10 NA Homo sapiens

GOA MOX014386 Genes associated with Computational Drug Signature PD 0183812 Genes associated with Computational Drug Signature PD-0183812, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB MOX014394 Genes associated with Computational Drug Signature PD166326 Genes associated with Computational Drug Signature PD166326, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB MOX017941 Genes associated with Computational Drug Signature Afatinib Genes associated with Computational Drug Signature Afatinib, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB IEI002742 Protein protein interactors of human gene CNPY2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNPY2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI011193 Protein protein interactors of human gene REV3L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene REV3L (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI013729 Protein protein interactors of human gene TIMP3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TIMP3 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI014826 Protein protein interactors of human gene UVSSA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UVSSA (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D TAX021089 GO:0031639 biological process plasminogen activation The process in which inactive plasminogen is processed to active plasmin. This process includes clea (more detail) 10 NA Homo sapiens

GOA WAG000643 e2f1 destruction pathway E2F-1 is a transcription factor that regulates the expression of genes involved in the cell cycle an (more detail) 10 NA Homo sapiens

BioCarta TAX013391 GO:0000394 biological process RNA splicing, via endonucleolytic cleavage and ligation Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites i (more detail) 10 NA Homo sapiens

GOA WIG001114 Genes involved in Purine catabolism (more detail) 10 NA Homo sapiens

MSigDB WIG001154 Genes involved in Removal of the Flap Intermediate from the C strand (more detail) 10 NA Homo sapiens

MSigDB WIG001702 TOB in Osteoblast Signaling TOB in Osteoblast Signaling (more detail) 10 NA Homo sapiens

Protein Lounge MEX001588 Genes associated with Kinase Inhibitor AG F 35231 Genes associated with Kinase Inhibitor AG-F-35231, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MOX000539 Genes associated with Computational Drug Signature Tetrac Genes associated with Computational Drug Signature Tetrac, curated by the Drug Signature Database (D (more detail) 10 25990557 Homo sapiens

DSigDB TAX017386 GO:0008641 molecular function ubiquitin like modifier activating enzyme activity Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through (more detail) 10 NA Homo sapiens

GOA TAX022776 GO:0035247 biological process peptidyl arginine omega N methylation The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue (more detail) 10 NA Homo sapiens

GOA TAX023130 GO:0035871 biological process protein K11 linked deubiquitination A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquiti (more detail) 10 NA Homo sapiens

GOA TAX017568 GO:0009173 biological process pyrimidine ribonucleoside monophosphate metabolic process The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound co (more detail) 10 NA Homo sapiens

GOA TAX028990 GO:0070544 biological process histone H3 K36 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the hi (more detail) 10 NA Homo sapiens

GOA TAX025413 GO:0046049 biological process UMP metabolic process The chemical reactions and pathways involving UMP, uridine monophosphate. (more detail) 10 NA Homo sapiens

GOA IEI008788 Protein protein interactors of human gene NFE2L3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFE2L3 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI009457 Protein protein interactors of human gene PAK1IP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAK1IP1 (SwissProt I (more detail) 10 17535438 Homo sapiens

I2D IEI003418 Protein protein interactors of human gene DDX31 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDX31 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI007758 Protein protein interactors of human gene MBD3L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MBD3L1 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D WAG001466 overview of telomerase protein component gene htert transcriptional regulation Telomerase is an enzyme which replicates the termil sequences of eukaryotic chromosomes, mely the te (more detail) 10 NA Homo sapiens

BioCarta TAX013257 GO:0000109 cellular component nucleotide excision repair complex Any complex formed of proteins that act in nucleotide-excision repair. (more detail) 10 NA Homo sapiens

GOA GEX000779 head and neck cancer lung cancer head and neck cancer lung cancer associated genes. PAGER constructed this gene set by grouping all g (more detail) 10 NA Homo sapiens

GAD WAG001540 Processing of Capped Intronless Pre mRNA (more detail) 10 NA Homo sapiens

Reactome WAG001144 Removal of the Flap Intermediate from the C strand (more detail) 10 NA Homo sapiens

Reactome WAG001149 Unwinding of DNA (more detail) 10 NA Homo sapiens

Reactome WAG000934 SLBP independent Processing of Histone Pre mRNAs (more detail) 10 NA Homo sapiens

Reactome TAX000998 Genes annotated by the GO term GO:0008250. A multisubunit protein complex in the endoplasmic reticulum membrane of eukaryotes that transfers lipid linked oligosaccharide precursor to asparagine residues on nascent proteins; includes at least nine different subunits, at least in yeast. (more detail) 10 NA Homo sapiens

MSigDB TAX000992 Genes annotated by the GO term GO:0000152. A ubiquitin ligase complex found in the nucleus. (more detail) 10 NA Homo sapiens

MSigDB WIG001130 Genes involved in Regulated proteolysis of p75NTR (more detail) 10 NA Homo sapiens

MSigDB MEX002334 Genes associated with Kinase Inhibitor Nilotinib Genes associated with Kinase Inhibitor Nilotinib, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MEX001700 Genes associated with Kinase Inhibitor PD 173074 Genes associated with Kinase Inhibitor PD 173074, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MEX002075 Genes associated with Kinase Inhibitor 1 [4 (4 aminothieno[2,3 d]pyrimidin 5 yl)phenyl] 3 (3 methylphenyl)urea Genes associated with Kinase Inhibitor 1-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-(3-methylp (more detail) 10 25990557 Homo sapiens

DSigDB MEX002168 Genes associated with Kinase Inhibitor GW782612X Genes associated with Kinase Inhibitor GW782612X, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB TAX013373 GO:0000338 biological process protein deneddylation The removal of a ubiquitin-like protein of the NEDD8 type from a protein. (more detail) 10 NA Homo sapiens

GOA TAX000253 Genes annotated by the GO term GO:0006783. The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. (more detail) 10 NA Homo sapiens

MSigDB TAX001187 Genes annotated by the GO term GO:0042826. Interacting selectively with the enzyme histone deacetylase. (more detail) 10 NA Homo sapiens

MSigDB TAX001188 Genes annotated by the GO term GO:0042054. Catalysis of the transfer of a methyl group (CH3 ) to a histone. (more detail) 10 NA Homo sapiens

MSigDB TAX001413 Genes annotated by the GO term GO:0042162. Interacting selectively with telomere associated DNA, usually characterized by highly repetitive sequences. (more detail) 10 NA Homo sapiens

MSigDB MAX002908 Examples of transcription factors whose activities are regulated by MAPK14 [GeneID=1432] phosphorylation. The mitogen-activated protein kinases (MAPKs) are a family of serine/threonine kinases that play an (more detail) 10 NA Homo sapiens

MSigDB TAX000732 Genes annotated by the GO term GO:0031123. Any process involved in forming the mature 3' end of an RNA molecule. (more detail) 10 NA Homo sapiens

MSigDB MEX001313 Genes associated with Kinase Inhibitor GSK2220400A Genes associated with Kinase Inhibitor GSK2220400A, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MEX000759 Genes associated with Approved Drug imatinib mesylate Genes associated with Approved Drug imatinib mesylate, curated by the Drug Signature Database (DSigD (more detail) 10 25990557 Homo sapiens

DSigDB MEX001679 Genes associated with Kinase Inhibitor Kinome 504 Genes associated with Kinase Inhibitor Kinome_504, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MOX002958 Genes associated with Computational Drug Signature nitroaspirin Genes associated with Computational Drug Signature nitroaspirin, curated by the Drug Signature Datab (more detail) 10 25990557 Homo sapiens

DSigDB TAX031782 GO:1900044 biological process regulation of protein K63 linked ubiquitination Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination. (more detail) 10 NA Homo sapiens

GOA PEX001755 Forkhead: Forkhead domain (more detail) 10 NA Homo sapiens

Pfam FEX010970 hsa miR 518d 3p HITS-CLIP, Functional MTI (Weak) (more detail) 10 NA Homo sapiens

mirTARbase IEI008905 Protein protein interactors of human gene NMRAL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NMRAL1 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI002317 Protein protein interactors of human gene CELF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CELF2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI010940 Protein protein interactors of human gene RAD51AP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAD51AP1 (SwissProt (more detail) 10 17535438 Homo sapiens

I2D IEI005911 Protein protein interactors of human gene HMGN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMGN3 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI014643 Protein protein interactors of human gene UCK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UCK2 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D TAX023838 GO:0042436 biological process indole containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole ( (more detail) 10 NA Homo sapiens

GOA WAG000695 Nicotinate metabolism (more detail) 10 NA Homo sapiens

Reactome TAX013349 GO:0000290 biological process deadenylation dependent decapping of nuclear transcribed mRNA Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a mini (more detail) 10 NA Homo sapiens

GOA TAX001377 Genes annotated by the GO term GO:0008373. Catalysis of the formation of sialylglycoconjugates via transfer of the sialic acid group from CMP to one of several glycoconjugate acceptors. (more detail) 10 NA Homo sapiens

MSigDB WIG001568 Inhibition of Ribosome Biogenesis by p19(ARF) Inhibition of Ribosome Biogenesis by p19(ARF) (more detail) 10 NA Homo sapiens

Protein Lounge TAX000990 Genes annotated by the GO term GO:0043596. The Y shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. (more detail) 10 NA Homo sapiens

MSigDB TAX000031 Genes annotated by the GO term GO:0042982. The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of beta amyloid, a glycoprotein associated with Alzheimer's disease. (more detail) 10 NA Homo sapiens

MSigDB TAX001324 Genes annotated by the GO term GO:0033558. Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate. (more detail) 10 NA Homo sapiens

MSigDB WIG000913 Genes involved in Hyaluronan uptake and degradation (more detail) 10 NA Homo sapiens

MSigDB FOX000430 Genes in the cancer module 101 (more detail) 10 NA Homo sapiens

MSigDB FOX000542 Genes in the cancer module 21 (more detail) 10 NA Homo sapiens

MSigDB TAX001149 Genes annotated by the GO term GO:0004520. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. (more detail) 10 NA Homo sapiens

MSigDB TAX001291 Genes annotated by the GO term GO:0016706. Catalysis of an oxidation reduction (redox) reaction in which hydrogen or electrons are transferred from 2 oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor. (more detail) 10 NA Homo sapiens

MSigDB TAX000991 Genes annotated by the GO term GO:0016607. A discrete extra nucleolar subnuclear domain, 20 50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy. (more detail) 10 NA Homo sapiens

MSigDB MEX000910 Genes associated with Approved Drug telaprevir Genes associated with Approved Drug telaprevir, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MEX001919 Genes associated with Kinase Inhibitor BMS 345541 free base Genes associated with Kinase Inhibitor BMS-345541 free base, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB MEX001641 Genes associated with Kinase Inhibitor 1 [4 (4 Aminothieno[2,3 D]pyrimidin 5 Yl)phenyl] 3 [2 Fluoro 5 (Trifluoromethyl)phenyl]urea Genes associated with Kinase Inhibitor 1-[4-(4-Aminothieno[2,3-D]pyrimidin-5-Yl)phenyl]-3-[2-Fluoro- (more detail) 10 25990557 Homo sapiens

DSigDB MEX001743 Genes associated with Kinase Inhibitor CHEMBL1956068 Genes associated with Kinase Inhibitor CHEMBL1956068, curated by the Drug Signature Database (DSigDB (more detail) 10 25990557 Homo sapiens

DSigDB MOX004187 Genes associated with Computational Drug Signature hexestrol Genes associated with Computational Drug Signature hexestrol, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB MOX013460 Genes associated with Computational Drug Signature Linifanib Genes associated with Computational Drug Signature Linifanib, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB TAX016421 GO:0006554 biological process lysine catabolic process The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid. (more detail) 10 NA Homo sapiens

GOA TAX016436 GO:0006569 biological process tryptophan catabolic process The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid (more detail) 10 NA Homo sapiens

GOA TAX030593 GO:0090657 biological process telomeric loop disassembly The telomere maintenance process in which telomeric loops are disassembled to permit efficient telom (more detail) 10 NA Homo sapiens

GOA TAX017184 GO:0008296 molecular function 3' 5' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule. (more detail) 10 NA Homo sapiens

GOA TAX031043 GO:0098599 molecular function palmitoyl hydrolase activity Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate. (more detail) 10 NA Homo sapiens

GOA TAX017526 GO:0009128 biological process purine nucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a (more detail) 10 NA Homo sapiens

GOA TAX024250 GO:0043247 biological process telomere maintenance in response to DNA damage Any process that occur in response to the presence of critically short or damaged telomeres. (more detail) 10 NA Homo sapiens

GOA TAX013621 GO:0001134 molecular function transcription regulator recruiting activity Interacting selectively and non-covalently with a specific transcription factor, which may be a sing (more detail) 10 NA Homo sapiens

GOA TAX018798 GO:0015937 biological process coenzyme A biosynthetic process The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5 (more detail) 10 NA Homo sapiens

GOA TAX019449 GO:0018026 biological process peptidyl lysine monomethylation The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine. (more detail) 10 NA Homo sapiens

GOA TAX019474 GO:0018158 biological process protein oxidation The modification of a protein amino acid by oxidation. (more detail) 10 NA Homo sapiens

GOA TAX020998 GO:0031442 biological process positive regulation of mRNA 3' end processing Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing. (more detail) 10 NA Homo sapiens

GOA TAX031702 GO:0140078 molecular function class I DNA (apurinic or apyrimidinic site) endonuclease activity Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving a (more detail) 10 NA Homo sapiens

GOA TAX016178 GO:0006188 biological process IMP biosynthetic process The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate. (more detail) 10 NA Homo sapiens

GOA TAX015237 GO:0004576 molecular function oligosaccharyl transferase activity Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbo (more detail) 10 NA Homo sapiens

GOA PEX002031 Metallophos: Calcineurin like phosphoesterase This family includes a diverse range of phosphoesterases 1, including protein phosphoserine phosphat (more detail) 10 NA Homo sapiens

Pfam IEI003853 Protein protein interactors of human gene DUSP7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP7 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI004655 Protein protein interactors of human gene FBXO45 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO45 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI005649 Protein protein interactors of human gene H2AC14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene H2AC14 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI006921 Protein protein interactors of human gene KLHL18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHL18 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI007734 Protein protein interactors of human gene MASP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MASP2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI014768 Protein protein interactors of human gene USP24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP24 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D WAG000834 il 3 signaling pathway Interleukin-3 promotes the proliferation and differentiation of hematopoietic cells through binding (more detail) 10 NA Homo sapiens

BioCarta WIG000335 Glycolysis Pathway Glycolysis was one of the first metabolic pathways studied and is one of the best understood, in ter (more detail) 10 NA Homo sapiens

MSigDB WIG000304 Apoptotic DNA fragmentation and tissue homeostasis Apoptotic cell death can be triggered by many different cellular stimuli, resulting in activation of (more detail) 10 NA Homo sapiens

MSigDB TAX000534 Genes annotated by the GO term GO:0006471. The transfer, from NAD, of ADP ribose to protein amino acids. (more detail) 10 NA Homo sapiens

MSigDB MEX001222 Genes associated with Kinase Inhibitor GSK 3 Inhibitor XIII Genes associated with Kinase Inhibitor GSK-3 Inhibitor XIII, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens

DSigDB MEX002390 Genes associated with Kinase Inhibitor CHEMBL212299 Genes associated with Kinase Inhibitor CHEMBL212299, curated by the Drug Signature Database (DSigDB) (more detail) 10 25990557 Homo sapiens

DSigDB MEX001737 Genes associated with Kinase Inhibitor GW612286X Genes associated with Kinase Inhibitor GW612286X, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens

DSigDB MOX000496 Genes associated with Computational Drug Signature Aspidin Genes associated with Computational Drug Signature Aspidin, curated by the Drug Signature Database ( (more detail) 10 25990557 Homo sapiens

DSigDB MOX003045 Genes associated with Computational Drug Signature Cyprodinil Genes associated with Computational Drug Signature Cyprodinil, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB TAX022130 GO:0033523 biological process histone H2B ubiquitination The modification of histone H2B by addition of ubiquitin groups. (more detail) 10 NA Homo sapiens

GOA TAX016414 GO:0006547 biological process histidine metabolic process The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. (more detail) 10 NA Homo sapiens

GOA TAX016463 GO:0006600 biological process creatine metabolic process The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a com (more detail) 10 NA Homo sapiens

GOA TAX017292 GO:0008474 molecular function palmitoyl (protein) hydrolase activity Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein. (more detail) 10 NA Homo sapiens

GOA TAX016193 GO:0006216 biological process cytidine catabolic process The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a wid (more detail) 10 NA Homo sapiens

GOA TAX031001 GO:0098505 molecular function G rich strand telomeric DNA binding Interacting selectively and non-covalently with G-rich, single-stranded, telomere-associated DNA. (more detail) 10 NA Homo sapiens

GOA TAX028951 GO:0070475 biological process rRNA base methylation The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in (more detail) 10 NA Homo sapiens

GOA TAX019280 GO:0016884 molecular function carbon nitrogen ligase activity, with glutamine as amido N donor Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases cat (more detail) 10 NA Homo sapiens

GOA TAX019282 GO:0016886 molecular function ligase activity, forming phosphoric ester bonds Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric (more detail) 10 NA Homo sapiens

GOA TAX021054 GO:0031571 biological process mitotic G1 DNA damage checkpoint A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G1/S t (more detail) 10 NA Homo sapiens

GOA TAX014641 GO:0003211 biological process cardiac ventricle formation The developmental process pertaining to the initial formation of a cardiac ventricle from unspecifie (more detail) 10 NA Homo sapiens

GOA MOX014383 Genes associated with Computational Drug Signature PD 0173956 Genes associated with Computational Drug Signature PD-0173956, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens

DSigDB IEI002469 Protein protein interactors of human gene CHD9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD9 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D IEI002835 Protein protein interactors of human gene COMMD6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD6 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI004565 Protein protein interactors of human gene FANCB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FANCB (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI011560 Protein protein interactors of human gene RPP25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPP25 (SwissProt ID= (more detail) 10 17535438 Homo sapiens

I2D IEI007412 Protein protein interactors of human gene LRRC14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRRC14 (SwissProt ID (more detail) 10 17535438 Homo sapiens

I2D IEI001576 Protein protein interactors of human gene C1orf174 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C1orf174 (SwissProt (more detail) 10 17535438 Homo sapiens

I2D IEI008506 Protein protein interactors of human gene MYT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYT1 (SwissProt ID=Q (more detail) 10 17535438 Homo sapiens

I2D TAX001163 Genes annotated by the GO term GO:0008417. Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid. (more detail) 10 NA Homo sapiens

MSigDB IEI006813 Protein protein interactors of human gene KIDINS220 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIDINS220 (SwissProt (more detail) 15 17535438 Homo sapiens

I2D IEI011291 Protein protein interactors of human gene RHOT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RHOT1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D TAX027892 GO:0060413 biological process atrial septum morphogenesis The developmental process in which atrial septum is generated and organized. The atrial septum separ (more detail) 15 NA Homo sapiens

GOA IEI006299 Protein protein interactors of human gene IL13RA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL13RA2 (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D IEI001618 Protein protein interactors of human gene C4A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C4A (SwissProt ID=P0 (more detail) 15 17535438 Homo sapiens

I2D IEI007500 Protein protein interactors of human gene LTV1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LTV1 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI013375 Protein protein interactors of human gene TAOK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAOK1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI004117 Protein protein interactors of human gene ELP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ELP4 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI003171 Protein protein interactors of human gene CWC22 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CWC22 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI012160 Protein protein interactors of human gene SH3PXD2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH3PXD2A (SwissProt (more detail) 15 17535438 Homo sapiens

I2D IEI003223 Protein protein interactors of human gene CYLC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CYLC2 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI015745 Protein protein interactors of human gene ZNF746 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF746 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI006892 Protein protein interactors of human gene KLF13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF13 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI012554 Protein protein interactors of human gene SLFN11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLFN11 (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI005737 Protein protein interactors of human gene HCFC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HCFC2 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI005037 Protein protein interactors of human gene GALNT12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GALNT12 (SwissProt I (more detail) 15 17535438 Homo sapiens

I2D IEI002698 Protein protein interactors of human gene CMSS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CMSS1 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI006770 Protein protein interactors of human gene KDM6B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KDM6B (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI006049 Protein protein interactors of human gene HSDL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSDL2 (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D TAX034224 GO:1990381 molecular function ubiquitin specific protease binding Interacting selectively and non-covalently with a ubiquitin-specific protease. (more detail) 15 NA Homo sapiens

GOA IEI008323 Protein protein interactors of human gene MTF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTF2 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI007470 Protein protein interactors of human gene LSM14A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSM14A (SwissProt ID (more detail) 15 17535438 Homo sapiens

I2D IEI012709 Protein protein interactors of human gene SNURF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNURF (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D IEI012047 Protein protein interactors of human gene SERPING1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERPING1 (SwissProt (more detail) 15 17535438 Homo sapiens

I2D IEI004703 Protein protein interactors of human gene FECH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FECH (SwissProt ID=P (more detail) 15 17535438 Homo sapiens

I2D TAX027179 GO:0051770 biological process positive regulation of nitric oxide synthase biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 15 NA Homo sapiens

GOA TAX026182 GO:0048485 biological process sympathetic nervous system development The process whose specific outcome is the progression of the sympathetic nervous system over time, f (more detail) 15 NA Homo sapiens

GOA TAX022982 GO:0035613 molecular function RNA stem loop binding Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is (more detail) 15 NA Homo sapiens

GOA TAX018938 GO:0016254 biological process preassembly of GPI anchor in ER membrane The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the e (more detail) 15 NA Homo sapiens

GOA IEI007002 Protein protein interactors of human gene KRI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KRI1 (SwissProt ID=Q (more detail) 15 17535438 Homo sapiens

I2D IEI003316 Protein protein interactors of human gene DBF4B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DBF4B (SwissProt ID= (more detail) 15 17535438 Homo sapiens

I2D MEX000539 Genes associated with Approved Drug triamcinolone Genes associated with Approved Drug triamcinolone, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens

DSigDB MOX002025 Genes associated with Computational Drug Signature CYFLUTHRIN Genes associated with Computational Drug Signature CYFLUTHRIN, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens

DSigDB WIG000342 Hypoxia Inducible Factor in the Cardiovascular System Hypoxia (or low O2 levels) affects various pathologies. First, tissue ischemia, a variation in O2 te (more detail) 15 NA Homo sapiens

MSigDB WAG000222 akt signaling pathway Many cell-surface receptors induce production of second messengers like PIP3, phosphatidylinositol 3 (more detail) 15 NA Homo sapiens

BioCarta MOX002651 Genes associated with Computational Drug Signature Oroxylin A Genes associated with Computational Drug Signature Oroxylin A, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens

DSigDB MOX000383 Genes associated with Computational Drug Signature Paraoxon methyl Genes associated with Computational Drug Signature Paraoxon-methyl, curated by the Drug Signature Da (more detail) 15 25990557 Homo sapiens

DSigDB WIG000114 LPA4 mediated signaling events (more detail) 15 NA Homo sapiens

MSigDB TAX000502 Genes annotated by the GO term GO:0043507. Any process that activates or increases the frequency, rate or extent of JUN kinase activity. (more detail) 15 NA Homo sapiens

MSigDB MOX000197 Genes associated with Computational Drug Signature naringin Genes associated with Computational Drug Signature naringin, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX000984 Genes associated with Computational Drug Signature 2 AMINOANTHRAQUINONE Genes associated with Computational Drug Signature 2-AMINOANTHRAQUINONE, curated by the Drug Signatu (more detail) 15 25990557 Homo sapiens

DSigDB MOX003456 Genes associated with Computational Drug Signature PCI 24781 Genes associated with Computational Drug Signature PCI-24781, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB TAX015216 GO:0004551 molecular function nucleotide diphosphatase activity Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides. (more detail) 15 NA Homo sapiens

GOA MOX002993 Genes associated with Computational Drug Signature L 741,626 Genes associated with Computational Drug Signature L-741,626, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX004612 Genes associated with Computational Drug Signature quinacrine Genes associated with Computational Drug Signature quinacrine, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens

DSigDB MEX003984 Genes associated with Perturbagen Signature profenamine Genes associated with Perturbagen Signature profenamine, curated by the Drug Signature Database (DSi (more detail) 15 25990557 Homo sapiens

DSigDB MOX004189 Genes associated with Computational Drug Signature 4 Hexylresorcinol Genes associated with Computational Drug Signature 4-Hexylresorcinol, curated by the Drug Signature (more detail) 15 25990557 Homo sapiens

DSigDB WIG000772 Genes involved in CREB phosphorylation through the activation of CaMKII (more detail) 15 NA Homo sapiens

MSigDB MOX001142 Genes associated with Computational Drug Signature Benzo[e]pyrene Genes associated with Computational Drug Signature Benzo[e]pyrene, curated by the Drug Signature Dat (more detail) 15 25990557 Homo sapiens

DSigDB WIG000779 Genes involved in Cyclin A/B1 associated events during G2/M transition (more detail) 15 NA Homo sapiens

MSigDB MOX015668 Genes associated with Computational Drug Signature Tyrphostin 25 Genes associated with Computational Drug Signature Tyrphostin 25, curated by the Drug Signature Data (more detail) 15 25990557 Homo sapiens

DSigDB MOX007581 Genes associated with Computational Drug Signature Cgs 15943 Genes associated with Computational Drug Signature Cgs 15943, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX000363 Genes associated with Computational Drug Signature alfacalcidol Genes associated with Computational Drug Signature alfacalcidol, curated by the Drug Signature Datab (more detail) 15 25990557 Homo sapiens

DSigDB MOX003572 Genes associated with Computational Drug Signature 49843 98 3 Genes associated with Computational Drug Signature 49843-98-3, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens

DSigDB MEX000667 Genes associated with Approved Drug sertraline hydrochloride Genes associated with Approved Drug sertraline hydrochloride, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX004792 Genes associated with Computational Drug Signature Metrifonate Genes associated with Computational Drug Signature Metrifonate, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB MOX000975 Genes associated with Computational Drug Signature 3,14 Dihydroxybufa 20,22 dienolide Genes associated with Computational Drug Signature 3,14-Dihydroxybufa-20,22-dienolide, curated by th (more detail) 15 25990557 Homo sapiens

DSigDB TAX000220 Genes annotated by the GO term GO:0051318. Progression through G1 phase, one of two 'gap' phases in the cell cycle; G1 is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis. (more detail) 15 NA Homo sapiens

MSigDB MOX006991 Genes associated with Computational Drug Signature amsacrine Genes associated with Computational Drug Signature amsacrine, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens

DSigDB MOX002164 Genes associated with Computational Drug Signature fumonisin b1 Genes associated with Computational Drug Signature fumonisin b1, curated by the Drug Signature Datab (more detail) 15 25990557 Homo sapiens

DSigDB WIG000060 Validated nuclear estrogen receptor beta network (more detail) 15 NA Homo sapiens

MSigDB WIG000404 Multi step Regulation of Transcription by Pitx2 Many transcription factors play essential roles in normal development by determining the proliferati (more detail) 15 NA Homo sapiens

MSigDB MOX002792 Genes associated with Computational Drug Signature CHEMBL55802 Genes associated with Computational Drug Signature CHEMBL55802, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens

DSigDB IEI010232 Protein protein interactors of human gene POLR3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR3B (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI010572 Protein protein interactors of human gene PRRC2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRRC2B (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI007983 Protein protein interactors of human gene MIDEAS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MIDEAS (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI014175 Protein protein interactors of human gene TRAM1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRAM1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI000097 Protein protein interactors of human gene ABRAXAS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ABRAXAS2 (SwissProt (more detail) 17 17535438 Homo sapiens

I2D IEI006537 Protein protein interactors of human gene ITGAX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ITGAX (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI003883 Protein protein interactors of human gene DYRK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DYRK4 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI002735 Protein protein interactors of human gene CNOT6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNOT6 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI010903 Protein protein interactors of human gene RAB6B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RAB6B (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI015410 Protein protein interactors of human gene ZNF189 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF189 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI008816 Protein protein interactors of human gene NGLY1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NGLY1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D TAX017877 GO:0010224 biological process response to UV B Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 17 NA Homo sapiens

GOA TAX023661 GO:0042093 biological process T helper cell differentiation The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helpe (more detail) 17 NA Homo sapiens

GOA IEI011390 Protein protein interactors of human gene RNF130 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF130 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D WEX000023 EGFR Signaling The genes related to egfr signaling (signaling pathways) in tumor using next-generation sequencer (N (more detail) 17 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI001425 Protein protein interactors of human gene BRD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRD2 (SwissProt ID=P (more detail) 17 17535438 Homo sapiens

I2D IEI001236 Protein protein interactors of human gene BATF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BATF2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI005816 Protein protein interactors of human gene HEXIM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HEXIM2 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI012064 Protein protein interactors of human gene SETD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SETD2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI004235 Protein protein interactors of human gene EPSTI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EPSTI1 (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI009525 Protein protein interactors of human gene PATL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PATL1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI002926 Protein protein interactors of human gene CPNE3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CPNE3 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI004392 Protein protein interactors of human gene F2RL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene F2RL1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI003493 Protein protein interactors of human gene DET1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DET1 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens

I2D IEI002487 Protein protein interactors of human gene CHMP1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHMP1A (SwissProt ID (more detail) 17 17535438 Homo sapiens

I2D IEI015323 Protein protein interactors of human gene ZFPM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZFPM2 (SwissProt ID= (more detail) 17 17535438 Homo sapiens

I2D IEI006224 Protein protein interactors of human gene IGF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGF1 (SwissProt ID=P (more detail) 17 17535438 Homo sapiens

I2D TAX023746 GO:0042274 biological process ribosomal small subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arr (more detail) 17 NA Homo sapiens

GOA TAX018196 GO:0010888 biological process negative regulation of lipid storage Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accu (more detail) 17 NA Homo sapiens

GOA MOX017878 Genes associated with Computational Drug Signature tranilast Genes associated with Computational Drug Signature tranilast, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens

DSigDB GEX168106 Simon et al., 2012 04 01, Genes and Development, A key role for EZH2 and associated genes in mouse and human adult T cell acute leukemia T-cell leukemia (T-ALL) Mutation type(Somatic mutation) (more detail) 17 22431509 Homo sapiens

NGS Catalog MOX004251 Genes associated with Computational Drug Signature labetalol Genes associated with Computational Drug Signature labetalol, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens

DSigDB WIG001248 Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) (more detail) 17 NA Homo sapiens

MSigDB WIG000170 Regulation of cytoplasmic and nuclear SMAD2/3 signaling (more detail) 17 NA Homo sapiens

MSigDB TAX000188 Genes annotated by the GO term GO:0048598. The process by which anatomical structures are generated and organized during the embryonic phase. Morphogenesis pertains to the creation of form. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. (more detail) 17 NA Homo sapiens

MSigDB TAX000638 Genes annotated by the GO term GO:0043506. Any process that modulates the frequency, rate or extent of JUN kinase activity. (more detail) 17 NA Homo sapiens

MSigDB TAX000472 Genes annotated by the GO term GO:0046148. The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin. (more detail) 17 NA Homo sapiens

MSigDB MOX014878 Genes associated with Computational Drug Signature rosmarinic acid Genes associated with Computational Drug Signature rosmarinic acid, curated by the Drug Signature Da (more detail) 17 25990557 Homo sapiens

DSigDB TAX000279 Genes annotated by the GO term GO:0051701. An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. (more detail) 17 NA Homo sapiens

MSigDB WAG001618 Reductive carboxylate cycle (CO2 fixation) (more detail) 17 NA Homo sapiens

KEGG MEX000034 Genes associated with Approved Drug amlexanox Genes associated with Approved Drug amlexanox, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens

DSigDB WIG000008 Cellular roles of Anthrax toxin (more detail) 17 NA Homo sapiens

MSigDB FOX000764 Genes in the cancer module 492 (more detail) 17 NA Homo sapiens

MSigDB WIG001458 Activation of NF KappaB by PKR Activation of NF-KappaB by PKR (more detail) 17 NA Homo sapiens

Protein Lounge WIG000450 TNFR2 Signaling Pathway TNFR2 is the receptor for the 171 amino acid 19 kD TNF(beta) (a.k.a. lymphotoxin). TNF(beta) is prod (more detail) 17 NA Homo sapiens

MSigDB MOX013197 Genes associated with Computational Drug Signature Isokaempferide Genes associated with Computational Drug Signature Isokaempferide, curated by the Drug Signature Dat (more detail) 17 25990557 Homo sapiens

DSigDB WIG001082 Genes involved in PKA mediated phosphorylation of CREB (more detail) 17 NA Homo sapiens

MSigDB MOX004892 Genes associated with Computational Drug Signature Phorbol 12,13 dibutyrate Genes associated with Computational Drug Signature Phorbol 12,13-dibutyrate, curated by the Drug Sig (more detail) 17 25990557 Homo sapiens

DSigDB MOX002707 Genes associated with Computational Drug Signature Brucinum Genes associated with Computational Drug Signature Brucinum, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens

DSigDB MOX001945 Genes associated with Computational Drug Signature AT 877 Genes associated with Computational Drug Signature AT 877, curated by the Drug Signature Database (D (more detail) 17 25990557 Homo sapiens

DSigDB FEX000679 Breast Habermann09 18genes Supplemental Table 2: Expression levels of genes that are potentially involved in the maintenance of (more detail) 17 19101988 Homo sapiens

GeneSigDB WAG001629 D Glutamine and D glutamate metabolism (more detail) 17 NA Homo sapiens

KEGG WAG001456 growth hormone signaling pathway Growth hormone plays a major role in regulating growth during childhood and adolescence and also reg (more detail) 17 NA Homo sapiens

BioCarta TAX014162 GO:0002294 biological process CD4 positive, alpha beta T cell differentiation involved in immune response The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized (more detail) 17 NA Homo sapiens

GOA MOX016917 Genes associated with Computational Drug Signature letrozole Genes associated with Computational Drug Signature letrozole, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens

DSigDB TAX000818 Genes annotated by the GO term GO:0019079. Any process involved directly in viral genome replication, including viral nucleotide metabolism. (more detail) 19 NA Homo sapiens

MSigDB FEX000156 Brain Hui04 33genes Table 1 SERM-responsible genes (more detail) 19 15604281 Homo sapiens

GeneSigDB MOX001820 Genes associated with Computational Drug Signature benazepril Genes associated with Computational Drug Signature benazepril, curated by the Drug Signature Databas (more detail) 19 25990557 Homo sapiens

DSigDB MOX013407 Genes associated with Computational Drug Signature leflunomide Genes associated with Computational Drug Signature leflunomide, curated by the Drug Signature Databa (more detail) 19 25990557 Homo sapiens

DSigDB MOX001236 Genes associated with Computational Drug Signature Rutaecarpine Genes associated with Computational Drug Signature Rutaecarpine, curated by the Drug Signature Datab (more detail) 19 25990557 Homo sapiens

DSigDB FEX001373 Leukemia Gebauer05 19genes Table 3a. Genes which are significantly regulated by stimulation with 1 ng/ml IL-1Beta in SW1353 cel (more detail) 19 15950496 Homo sapiens

GeneSigDB MOX005044 Genes associated with Computational Drug Signature 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE Genes associated with Computational Drug Signature 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE, cu (more detail) 19 25990557 Homo sapiens

DSigDB MOX001585 Genes associated with Computational Drug Signature prostaglandin J2 Genes associated with Computational Drug Signature prostaglandin J2, curated by the Drug Signature D (more detail) 19 25990557 Homo sapiens

DSigDB GEX167149 LDL cholesterol Genetic variants influencing circulating lipid levels and risk of coronary artery disease. (more detail) 19 20864672 Homo sapiens

GWAS Catalog WIG000375 Role of MEF2D in T cell Apoptosis Mef2 pathway. (more detail) 19 NA Homo sapiens

MSigDB TAX000170 Genes annotated by the GO term GO:0000077. A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds. (more detail) 19 NA Homo sapiens

MSigDB FEX000886 Colon Grade06 19genes Table 1b. Expression and P values for additional genes from ingenuity pathway analysis networks in F (more detail) 19 16397240 Homo sapiens

GeneSigDB TAX014199 GO:0002360 biological process T cell lineage commitment The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell. (more detail) 19 NA Homo sapiens

GOA MOX002069 Genes associated with Computational Drug Signature mometasone furoate Genes associated with Computational Drug Signature mometasone furoate, curated by the Drug Signature (more detail) 19 25990557 Homo sapiens

DSigDB MOX004553 Genes associated with Computational Drug Signature Chloroethylene Genes associated with Computational Drug Signature Chloroethylene, curated by the Drug Signature Dat (more detail) 19 25990557 Homo sapiens

DSigDB MOX004177 Genes associated with Computational Drug Signature heme Genes associated with Computational Drug Signature heme, curated by the Drug Signature Database (DSi (more detail) 19 25990557 Homo sapiens

DSigDB MEX000416 Genes associated with Approved Drug medroxyprogesterone acetate Genes associated with Approved Drug medroxyprogesterone acetate, curated by the Drug Signature Datab (more detail) 19 25990557 Homo sapiens

DSigDB TAX014052 GO:0002082 biological process regulation of oxidative phosphorylation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 19 NA Homo sapiens

GOA WIG000198 Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. na (more detail) 19 NA Homo sapiens

MSigDB WAG000224 tnf/stress related signaling TNF acts on several different sigling pathways through two cell surface receptors, TNFR1 and TNFR2 ( (more detail) 19 NA Homo sapiens

BioCarta TAX034895 GO:2000738 biological process positive regulation of stem cell differentiation Any process that activates or increases the frequency, rate or extent of stem cell differentiation. (more detail) 19 NA Homo sapiens

GOA IEI002988 Protein protein interactors of human gene CRIP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CRIP2 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI003548 Protein protein interactors of human gene DHX58 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DHX58 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX027574 GO:0055093 biological process response to hyperoxia Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 19 NA Homo sapiens

GOA IEI005822 Protein protein interactors of human gene HGF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HGF (SwissProt ID=P1 (more detail) 19 17535438 Homo sapiens

I2D IEI004148 Protein protein interactors of human gene EMSY from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EMSY (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D IEI012263 Protein protein interactors of human gene SLA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLA (SwissProt ID=Q1 (more detail) 19 17535438 Homo sapiens

I2D IEI005149 Protein protein interactors of human gene GEMIN7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GEMIN7 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D TAX029098 GO:0070741 biological process response to interleukin 6 Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 19 NA Homo sapiens

GOA IEI001075 Protein protein interactors of human gene ATP2B4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP2B4 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI007243 Protein protein interactors of human gene LGMN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LGMN (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D IEI010198 Protein protein interactors of human gene POLE2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLE2 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D TAX032360 GO:1902074 biological process response to salt Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 19 NA Homo sapiens

GOA TAX035004 GO:2001014 biological process regulation of skeletal muscle cell differentiation Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. (more detail) 19 NA Homo sapiens

GOA IEI014419 Protein protein interactors of human gene TTC27 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTC27 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI003831 Protein protein interactors of human gene DUS3L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUS3L (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI003762 Protein protein interactors of human gene DPP9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DPP9 (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens

I2D TAX032678 GO:1902884 biological process positive regulation of response to oxidative stress Any process that activates or increases the frequency, rate or extent of response to oxidative stres (more detail) 19 NA Homo sapiens

GOA TAX021615 GO:0032527 biological process protein exit from endoplasmic reticulum The directed movement of proteins from the endoplasmic reticulum. (more detail) 19 NA Homo sapiens

GOA TAX023176 GO:0035967 biological process cellular response to topologically incorrect protein Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 19 NA Homo sapiens

GOA IEI005206 Protein protein interactors of human gene GINS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GINS2 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI001273 Protein protein interactors of human gene BCKDK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCKDK (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI000860 Protein protein interactors of human gene ARID2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARID2 (SwissProt ID= (more detail) 19 17535438 Homo sapiens

I2D IEI015211 Protein protein interactors of human gene ZBTB32 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB32 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI000588 Protein protein interactors of human gene ANKMY2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANKMY2 (SwissProt ID (more detail) 19 17535438 Homo sapiens

I2D IEI015418 Protein protein interactors of human gene ZNF207 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF207 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI003126 Protein protein interactors of human gene CTNND2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTNND2 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI004857 Protein protein interactors of human gene FOXA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXA1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI005749 Protein protein interactors of human gene HDAC10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HDAC10 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI000442 Protein protein interactors of human gene AKR1B1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKR1B1 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI005567 Protein protein interactors of human gene GSTO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GSTO1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI008138 Protein protein interactors of human gene MPP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MPP1 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D TAX032836 GO:1903203 biological process regulation of oxidative stress induced neuron death Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron death. (more detail) 21 NA Homo sapiens

GOA IEI009413 Protein protein interactors of human gene P4HA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene P4HA1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI015821 Protein protein interactors of human gene ZNHIT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNHIT1 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI007215 Protein protein interactors of human gene LENG8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LENG8 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D TAX025225 GO:0045686 biological process negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiat (more detail) 21 NA Homo sapiens

GOA IEI014040 Protein protein interactors of human gene TNKS1BP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNKS1BP1 (SwissProt (more detail) 21 17535438 Homo sapiens

I2D TAX018640 GO:0015645 molecular function fatty acid ligase activity Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP. (more detail) 21 NA Homo sapiens

GOA IEI002586 Protein protein interactors of human gene CKS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CKS2 (SwissProt ID=P (more detail) 21 17535438 Homo sapiens

I2D IEI011019 Protein protein interactors of human gene RASD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RASD2 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI005254 Protein protein interactors of human gene GLMN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GLMN (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI007234 Protein protein interactors of human gene LGALS7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LGALS7 (SwissProt ID (more detail) 21 17535438 Homo sapiens

I2D IEI000454 Protein protein interactors of human gene AKT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKT3 (SwissProt ID=Q (more detail) 21 17535438 Homo sapiens

I2D IEI003997 Protein protein interactors of human gene EGLN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EGLN2 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI007122 Protein protein interactors of human gene LAMA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LAMA4 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI001743 Protein protein interactors of human gene CAMK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAMK1 (SwissProt ID= (more detail) 21 17535438 Homo sapiens

I2D IEI004384 Protein protein interactors of human gene F10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene F10 (SwissProt ID=P0 (more detail) 21 17535438 Homo sapiens

I2D MOX014579 Genes associated with Computational Drug Signature Poriol Genes associated with Computational Drug Signature Poriol, curated by the Drug Signature Database (D (more detail) 21 25990557 Homo sapiens

DSigDB MAX002363 Proteins phosporylated in HCT116 cells (colon cancer) upon p53 [GeneID=7157] activation. The p53 tumor suppressor regulates transcription of target genes. We have previously analysed the p5 (more detail) 21 NA Homo sapiens

MSigDB MAX003277 Proteins associated with ZNF143 [GeneID=7702] in HeLa cells, based on MudPIT analysis. Chromatin remodeling and histone modification are essential for eukaryotic transcription regulation, (more detail) 21 NA Homo sapiens

MSigDB MOX017139 Genes associated with Computational Drug Signature Axitinib Genes associated with Computational Drug Signature Axitinib, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens

DSigDB TAX000337 Genes annotated by the GO term GO:0007498. The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. (more detail) 21 NA Homo sapiens

MSigDB MOX017223 Genes associated with Computational Drug Signature triamcinolone Genes associated with Computational Drug Signature triamcinolone, curated by the Drug Signature Data (more detail) 21 25990557 Homo sapiens

DSigDB MEX000915 Genes associated with Approved Drug clomifene citrate Genes associated with Approved Drug clomifene citrate, curated by the Drug Signature Database (DSigD (more detail) 21 25990557 Homo sapiens

DSigDB MOX016400 Genes associated with Computational Drug Signature nimodipine Genes associated with Computational Drug Signature nimodipine, curated by the Drug Signature Databas (more detail) 21 25990557 Homo sapiens

DSigDB TAX000138 Genes annotated by the GO term GO:0051188. The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein. (more detail) 21 NA Homo sapiens

MSigDB WIG001939 EBV LMP1 signaling EBV LMP1 signaling (more detail) 21 NA Homo sapiens

WikiPathway MAX002839 Genes modulated in HeLa cells (cervical carcinoma) by TNF [GeneID=7124] not via NFKB pathway. Tumor necrosis factor (TNF) is a pro-inflammatory cytokine that controls expression of inflammatory (more detail) 21 NA Homo sapiens

MSigDB MOX017247 Genes associated with Computational Drug Signature ETHANE Genes associated with Computational Drug Signature ETHANE, curated by the Drug Signature Database (D (more detail) 21 25990557 Homo sapiens

DSigDB MOX012587 Genes associated with Computational Drug Signature ethinyl estradiol Genes associated with Computational Drug Signature ethinyl estradiol, curated by the Drug Signature (more detail) 21 25990557 Homo sapiens

DSigDB MOX005730 Genes associated with Computational Drug Signature 2 Methoxy 1,4 naphthoquinone Genes associated with Computational Drug Signature 2-Methoxy-1,4-naphthoquinone, curated by the Drug (more detail) 21 25990557 Homo sapiens

DSigDB MEX000659 Genes associated with Approved Drug paroxetine hydrochloride Genes associated with Approved Drug paroxetine hydrochloride, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens

DSigDB MOX000659 Genes associated with Computational Drug Signature Styrene oxide Genes associated with Computational Drug Signature Styrene oxide, curated by the Drug Signature Data (more detail) 21 25990557 Homo sapiens

DSigDB MOX004270 Genes associated with Computational Drug Signature loperamide Genes associated with Computational Drug Signature loperamide, curated by the Drug Signature Databas (more detail) 21 25990557 Homo sapiens

DSigDB TAX014685 GO:0003300 biological process cardiac muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardi (more detail) 21 NA Homo sapiens

GOA MOX015416 Genes associated with Computational Drug Signature tamoxifen Genes associated with Computational Drug Signature tamoxifen, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens

DSigDB FEX011520 hsa miR 6881 5p HITS-CLIP, Functional MTI (Weak) (more detail) 21 NA Homo sapiens

mirTARbase MOX004424 Genes associated with Computational Drug Signature nitrofurantoin Genes associated with Computational Drug Signature nitrofurantoin, curated by the Drug Signature Dat (more detail) 21 25990557 Homo sapiens

DSigDB TAX018392 GO:0014842 biological process regulation of skeletal muscle satellite cell proliferation Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell prolifera (more detail) 12 NA Homo sapiens

GOA IEI001364 Protein protein interactors of human gene BLVRA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BLVRA (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI009423 Protein protein interactors of human gene PABPC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PABPC3 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI004643 Protein protein interactors of human gene FBXO30 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO30 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI012120 Protein protein interactors of human gene SGK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SGK3 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI005977 Protein protein interactors of human gene HOXB6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXB6 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI012669 Protein protein interactors of human gene SNAPC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNAPC4 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI012931 Protein protein interactors of human gene SPSB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPSB2 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI000594 Protein protein interactors of human gene ANKRD13A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANKRD13A (SwissProt (more detail) 12 17535438 Homo sapiens

I2D IEI008274 Protein protein interactors of human gene MSH4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MSH4 (SwissProt ID=O (more detail) 12 17535438 Homo sapiens

I2D TAX023418 GO:0036499 biological process PERK mediated unfolded protein response A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR (more detail) 12 NA Homo sapiens

GOA IEI002858 Protein protein interactors of human gene COPS9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COPS9 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI006356 Protein protein interactors of human gene IL5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL5 (SwissProt ID=P0 (more detail) 12 17535438 Homo sapiens

I2D IEI013605 Protein protein interactors of human gene TFB2M from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TFB2M (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX023431 GO:0036513 cellular component Derlin 1 retrotranslocation complex A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degra (more detail) 12 NA Homo sapiens

GOA IEI008943 Protein protein interactors of human gene NOP14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOP14 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI009194 Protein protein interactors of human gene NVL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NVL (SwissProt ID=O1 (more detail) 12 17535438 Homo sapiens

I2D IEI004624 Protein protein interactors of human gene FBXL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXL3 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI005414 Protein protein interactors of human gene GPN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GPN3 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI006301 Protein protein interactors of human gene IL15RA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL15RA (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI013524 Protein protein interactors of human gene TDGF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TDGF1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI000521 Protein protein interactors of human gene ALX4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ALX4 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI001107 Protein protein interactors of human gene ATP6V0D1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP6V0D1 (SwissProt (more detail) 12 17535438 Homo sapiens

I2D IEI001451 Protein protein interactors of human gene BRWD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRWD1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D IEI009859 Protein protein interactors of human gene PHKB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHKB (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI010459 Protein protein interactors of human gene PRG2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRG2 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D TAX021073 GO:0031597 cellular component cytosolic proteasome complex A proteasome complex found in the cytosol of a cell. (more detail) 12 NA Homo sapiens

GOA IEI002679 Protein protein interactors of human gene CLTB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLTB (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI003593 Protein protein interactors of human gene DLGAP5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLGAP5 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI011406 Protein protein interactors of human gene RNF165 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF165 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI007187 Protein protein interactors of human gene LCOR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LCOR (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI007392 Protein protein interactors of human gene LRIG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LRIG1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX028887 GO:0070365 biological process hepatocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a hepatocy (more detail) 12 NA Homo sapiens

GOA TAX018792 GO:0015929 molecular function hexosaminidase activity Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) re (more detail) 12 NA Homo sapiens

GOA TAX014950 GO:0004062 molecular function aryl sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bispho (more detail) 12 NA Homo sapiens

GOA TAX034548 GO:2000232 biological process regulation of rRNA processing Any process that modulates the frequency, rate or extent of rRNA processing. (more detail) 12 NA Homo sapiens

GOA IEI015202 Protein protein interactors of human gene ZBTB18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB18 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI003403 Protein protein interactors of human gene DDT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DDT (SwissProt ID=P3 (more detail) 12 17535438 Homo sapiens

I2D IEI005094 Protein protein interactors of human gene GBE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GBE1 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens

I2D IEI011549 Protein protein interactors of human gene RPL7L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL7L1 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI014635 Protein protein interactors of human gene UBXN4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBXN4 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX029235 GO:0070989 biological process oxidative demethylation The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. ele (more detail) 12 NA Homo sapiens

GOA IEI008018 Protein protein interactors of human gene MKRN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MKRN1 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX022628 GO:0034709 cellular component methylosome A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifi (more detail) 12 NA Homo sapiens

GOA TAX030803 GO:0097329 biological process response to antimetabolite Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 12 NA Homo sapiens

GOA IEI004492 Protein protein interactors of human gene FAM193B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM193B (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI006440 Protein protein interactors of human gene INTS8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INTS8 (SwissProt ID= (more detail) 12 17535438 Homo sapiens

I2D TAX017729 GO:0009635 biological process response to herbicide Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 12 NA Homo sapiens

GOA TAX025101 GO:0045414 biological process regulation of interleukin 8 biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 12 NA Homo sapiens

GOA TAX019214 GO:0016783 molecular function sulfurtransferase activity Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor). (more detail) 12 NA Homo sapiens

GOA IEI009784 Protein protein interactors of human gene PFKFB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PFKFB3 (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI011097 Protein protein interactors of human gene RBM6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM6 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens

I2D IEI011941 Protein protein interactors of human gene SEC61A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SEC61A2 (SwissProt I (more detail) 12 17535438 Homo sapiens

I2D IEI000112 Protein protein interactors of human gene ACADSB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACADSB (SwissProt ID (more detail) 12 17535438 Homo sapiens

I2D IEI000412 Protein protein interactors of human gene AK1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AK1 (SwissProt ID=P0 (more detail) 12 17535438 Homo sapiens

I2D TAX020570 GO:0030575 biological process nuclear body organization A process that is carried out at the cellular level which results in the assembly, arrangement of co (more detail) 12 NA Homo sapiens

GOA MOX007458 Genes associated with Computational Drug Signature calcitriol Genes associated with Computational Drug Signature calcitriol, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB WAG001468 il 7 signal transduction IL-7 is a key cytokine in the immune system, essential for normal development of B cells and T cells (more detail) 12 NA Homo sapiens

BioCarta TAX000232 Genes annotated by the GO term GO:0006041. The chemical reactions and pathways involving glucosamine (2 amino 2 deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin. (more detail) 12 NA Homo sapiens

MSigDB WAG000231 granzyme a mediated apoptosis pathway One mechanism used by cytotoxic T cells to kill tumor cells and virus-infected cells is the release (more detail) 12 NA Homo sapiens

BioCarta WIG000826 Genes involved in ERKs are inactivated (more detail) 12 NA Homo sapiens

MSigDB WIG000661 Genes involved in Activation of Chaperones by ATF6 alpha (more detail) 12 NA Homo sapiens

MSigDB MOX002319 Genes associated with Computational Drug Signature mycophenolate mofetil Genes associated with Computational Drug Signature mycophenolate mofetil, curated by the Drug Signat (more detail) 12 25990557 Homo sapiens

DSigDB MOX014118 Genes associated with Computational Drug Signature NSC 645827 Genes associated with Computational Drug Signature NSC-645827, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB WAG001032 rb tumor suppressor/checkpoint signaling in response to dna damage Cell cycle checkpoint controls at the G1 to S transition and the G2 to M transition prevent the cell (more detail) 12 NA Homo sapiens

BioCarta MEX000350 Genes associated with Approved Drug dexamethasone Genes associated with Approved Drug dexamethasone, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MEX001056 Genes associated with Approved Drug cefdinir Genes associated with Approved Drug cefdinir, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB MOX001104 Genes associated with Computational Drug Signature BAPTA Genes associated with Computational Drug Signature BAPTA, curated by the Drug Signature Database (DS (more detail) 12 25990557 Homo sapiens

DSigDB MOX004019 Genes associated with Computational Drug Signature DL DOPA Genes associated with Computational Drug Signature DL-DOPA, curated by the Drug Signature Database ( (more detail) 12 25990557 Homo sapiens

DSigDB WAG000524 TRAF6 Mediated Induction of the antiviral cytokine IFN alpha/beta cascade (more detail) 12 NA Homo sapiens

Reactome MOX000715 Genes associated with Computational Drug Signature 2 Aminobiphenyl Genes associated with Computational Drug Signature 2-Aminobiphenyl, curated by the Drug Signature Da (more detail) 12 25990557 Homo sapiens

DSigDB MOX006139 Genes associated with Computational Drug Signature 483 60 3 Genes associated with Computational Drug Signature 483-60-3, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB MOX002260 Genes associated with Computational Drug Signature 5,7 Dimethoxyflavone Genes associated with Computational Drug Signature 5,7-Dimethoxyflavone, curated by the Drug Signatu (more detail) 12 25990557 Homo sapiens

DSigDB WIG000456 Control of Gene Expression by Vitamin D Receptor The vitamin D receptor, VDR is the mediator of all genomic actions of vitamin D3 and its analogs. It (more detail) 12 NA Homo sapiens

MSigDB MAX000646 The lung adenocarcinoma TSP (tumor sequencing project) genes with significantly higher frequencies of nonsense, splice site, and frame shift mutations. Determining the genetic basis of cancer requires comprehensive analyses of large collections of hist (more detail) 12 NA Homo sapiens

MSigDB WIG000805 Genes involved in Downregulation of ERBB2:ERBB3 signaling (more detail) 12 NA Homo sapiens

MSigDB WIG001023 Genes involved in NF kB activation through FADD/RIP 1 pathway mediated by caspase 8 and 10 (more detail) 12 NA Homo sapiens

MSigDB WIG001157 Genes involved in Resolution of AP sites via the single nucleotide replacement pathway (more detail) 12 NA Homo sapiens

MSigDB PEX000411 AAA: ATPase family associated with various cellular activities (AAA) AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, o (more detail) 12 NA Homo sapiens

Pfam MOX012563 Genes associated with Computational Drug Signature Erlotinib Genes associated with Computational Drug Signature Erlotinib, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB MOX015623 Genes associated with Computational Drug Signature Trifluridine Genes associated with Computational Drug Signature Trifluridine, curated by the Drug Signature Datab (more detail) 12 25990557 Homo sapiens

DSigDB MOX015993 Genes associated with Computational Drug Signature {5 fluoro 2 methyl 1 [4 (methylsulfinyl)benzylidene] 1h inden 3 yl}acetic acid Genes associated with Computational Drug Signature {5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylide (more detail) 12 25990557 Homo sapiens

DSigDB MOX017940 Genes associated with Computational Drug Signature cefaclor Genes associated with Computational Drug Signature cefaclor, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB WIG000454 Trka Receptor Signaling Pathway Nerve growth factor (NGF) is a neurotrophic factor that stimulates neuronal survival and growth thro (more detail) 12 NA Homo sapiens

MSigDB FOX000593 Genes in the cancer module 272 (more detail) 12 NA Homo sapiens

MSigDB WIG000928 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 (more detail) 12 NA Homo sapiens

MSigDB MEX000927 Genes associated with Approved Drug diclofenac sodium Genes associated with Approved Drug diclofenac sodium, curated by the Drug Signature Database (DSigD (more detail) 12 25990557 Homo sapiens

DSigDB MEX000753 Genes associated with Approved Drug clofarabine Genes associated with Approved Drug clofarabine, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens

DSigDB PEX001984 Methyltransf 11: Methyltransferase domain Members of this family are SAM dependent methyltransferases. (more detail) 12 NA Homo sapiens

Pfam WAG001263 Hypoxic and oxygen homeostasis regulation of HIF 1 alpha (more detail) 12 NA Homo sapiens

NCI-Nature Curated TAX000879 Genes annotated by the GO term GO:0005665. RNA polymerase II, one of three nuclear DNA directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. (more detail) 12 NA Homo sapiens

MSigDB MOX014228 Genes associated with Computational Drug Signature ofloxacin Genes associated with Computational Drug Signature ofloxacin, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB TAX001381 Genes annotated by the GO term GO:0046332. Interacting selectively with a SMAD signaling protein. (more detail) 12 NA Homo sapiens

MSigDB MOX004548 Genes associated with Computational Drug Signature PLATINUM Genes associated with Computational Drug Signature PLATINUM, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB MOX002932 Genes associated with Computational Drug Signature AZARIBINE Genes associated with Computational Drug Signature AZARIBINE, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens

DSigDB MOX012000 Genes associated with Computational Drug Signature Cladribine Genes associated with Computational Drug Signature Cladribine, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB PEX002387 FGF: Fibroblast growth factor Fibroblast growth factors are a family of proteins involved in growth and differentiation in a wide (more detail) 12 NA Homo sapiens

Pfam MOX014858 Genes associated with Computational Drug Signature Ro 4396686 Genes associated with Computational Drug Signature Ro-4396686, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB MOX014927 Genes associated with Computational Drug Signature S (+) Rolipram Genes associated with Computational Drug Signature S-(+)-Rolipram, curated by the Drug Signature Dat (more detail) 12 25990557 Homo sapiens

DSigDB WAG000421 multiple antiapoptotic pathways from igf 1r signaling lead to bad phosphorylation IGF-1R, the type 1 receptor for insulin-like growth factor, mediates cell survival and growth in res (more detail) 12 NA Homo sapiens

BioCarta MOX004952 Genes associated with Computational Drug Signature 38966 21 1 Genes associated with Computational Drug Signature 38966-21-1, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens

DSigDB TAX028108 GO:0060742 biological process epithelial cell differentiation involved in prostate gland development The process in which a relatively unspecialized cell acquires specialized features of an epithelial (more detail) 9 NA Homo sapiens

GOA TAX015962 GO:0005838 cellular component proteasome regulatory particle A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex rec (more detail) 9 NA Homo sapiens

GOA IEI002347 Protein protein interactors of human gene CENPV from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CENPV (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D TAX023788 GO:0042354 biological process L fucose metabolic process The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in (more detail) 9 NA Homo sapiens

GOA TAX023831 GO:0042424 biological process catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically (more detail) 9 NA Homo sapiens

GOA TAX022916 GO:0035520 biological process monoubiquitinated protein deubiquitination The removal of the ubiquitin group from a monoubiquitinated protein. (more detail) 9 NA Homo sapiens

GOA TAX017556 GO:0009158 biological process ribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a (more detail) 9 NA Homo sapiens

GOA TAX017566 GO:0009169 biological process purine ribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphat (more detail) 9 NA Homo sapiens

GOA TAX027233 GO:0051880 molecular function G quadruplex DNA binding Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four (more detail) 9 NA Homo sapiens

GOA TAX032254 GO:1901750 biological process leukotriene D4 biosynthetic process The chemical reactions and pathways resulting in the formation of leukotriene D4. (more detail) 9 NA Homo sapiens

GOA IEI010267 Protein protein interactors of human gene POTEE from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POTEE (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI006828 Protein protein interactors of human gene KIF20B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIF20B (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D TAX029262 GO:0071028 biological process nuclear mRNA surveillance The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nu (more detail) 9 NA Homo sapiens

GOA TAX030308 GO:0090070 biological process positive regulation of ribosome biogenesis Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis (more detail) 9 NA Homo sapiens

GOA TAX029017 GO:0070578 cellular component RISC loading complex A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RIS (more detail) 9 NA Homo sapiens

GOA TAX025466 GO:0046130 biological process purine ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucle (more detail) 9 NA Homo sapiens

GOA TAX025842 GO:0046972 molecular function histone acetyltransferase activity (H4 K16 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acet (more detail) 9 NA Homo sapiens

GOA TAX026490 GO:0050654 biological process chondroitin sulfate proteoglycan metabolic process The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein who (more detail) 9 NA Homo sapiens

GOA IEI008791 Protein protein interactors of human gene NFIB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NFIB (SwissProt ID=O (more detail) 9 17535438 Homo sapiens

I2D IEI002833 Protein protein interactors of human gene COMMD4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD4 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI003505 Protein protein interactors of human gene DGKA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DGKA (SwissProt ID=P (more detail) 9 17535438 Homo sapiens

I2D IEI005839 Protein protein interactors of human gene HIF3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HIF3A (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI012886 Protein protein interactors of human gene SPINK5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPINK5 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI006903 Protein protein interactors of human gene KLF9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLF9 (SwissProt ID=Q (more detail) 9 17535438 Homo sapiens

I2D IEI013687 Protein protein interactors of human gene THTPA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene THTPA (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI015175 Protein protein interactors of human gene YTHDF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene YTHDF3 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI010342 Protein protein interactors of human gene PPP1R12B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R12B (SwissProt (more detail) 9 17535438 Homo sapiens

I2D IEI004835 Protein protein interactors of human gene FN3KRP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FN3KRP (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI015861 Protein protein interactors of human gene ZSWIM8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZSWIM8 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI010320 Protein protein interactors of human gene PPIL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPIL4 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI004617 Protein protein interactors of human gene FBXL17 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXL17 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI004872 Protein protein interactors of human gene FOXJ3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FOXJ3 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI005802 Protein protein interactors of human gene HERC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HERC6 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI013117 Protein protein interactors of human gene STK19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STK19 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI000334 Protein protein interactors of human gene AFAP1L2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AFAP1L2 (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D IEI000587 Protein protein interactors of human gene ANKLE2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANKLE2 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI014259 Protein protein interactors of human gene TRIM52 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM52 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI000971 Protein protein interactors of human gene ASCL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASCL1 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D TAX022662 GO:0034770 biological process histone H4 K20 methylation The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of (more detail) 9 NA Homo sapiens

GOA TAX028922 GO:0070419 cellular component nonhomologous end joining complex A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. (more detail) 9 NA Homo sapiens

GOA TAX023363 GO:0036374 molecular function glutathione hydrolase activity Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate. (more detail) 9 NA Homo sapiens

GOA TAX030850 GO:0097428 biological process protein maturation by iron sulfur cluster transfer The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that (more detail) 9 NA Homo sapiens

GOA TAX029368 GO:0071287 biological process cellular response to manganese ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 9 NA Homo sapiens

GOA TAX021505 GO:0032389 cellular component MutLalpha complex A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In h (more detail) 9 NA Homo sapiens

GOA IEI001450 Protein protein interactors of human gene BRSK2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BRSK2 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D TAX029188 GO:0070922 biological process small RNA loading onto RISC The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (more detail) 9 NA Homo sapiens

GOA TAX023419 GO:0036500 biological process ATF6 mediated unfolded protein response A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (act (more detail) 9 NA Homo sapiens

GOA TAX017426 GO:0008821 molecular function crossover junction endodeoxyribonuclease activity Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossov (more detail) 9 NA Homo sapiens

GOA TAX024015 GO:0042776 biological process mitochondrial ATP synthesis coupled proton transport The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (pr (more detail) 9 NA Homo sapiens

GOA TAX017531 GO:0009133 biological process nucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compou (more detail) 9 NA Homo sapiens

GOA TAX024086 GO:0042987 biological process amyloid precursor protein catabolic process The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), t (more detail) 9 NA Homo sapiens

GOA TAX024814 GO:0044666 cellular component MLL3/4 complex A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protei (more detail) 9 NA Homo sapiens

GOA TAX019419 GO:0017162 molecular function aryl hydrocarbon receptor binding Interacting selectively and non-covalently with an aryl hydrocarbon receptor. (more detail) 9 NA Homo sapiens

GOA TAX025438 GO:0046085 biological process adenosine metabolic process The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found wi (more detail) 9 NA Homo sapiens

GOA TAX032862 GO:1903265 biological process positive regulation of tumor necrosis factor mediated signaling pathway Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-media (more detail) 9 NA Homo sapiens

GOA TAX016873 GO:0007260 biological process tyrosine phosphorylation of STAT protein The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and (more detail) 9 NA Homo sapiens

GOA TAX017606 GO:0009215 biological process purine deoxyribonucleoside triphosphate metabolic process The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound co (more detail) 9 NA Homo sapiens

GOA TAX024562 GO:0043995 molecular function histone acetyltransferase activity (H4 K5 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acety (more detail) 9 NA Homo sapiens

GOA TAX019781 GO:0019695 biological process choline metabolic process The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino al (more detail) 9 NA Homo sapiens

GOA TAX019491 GO:0018202 biological process peptidyl histidine modification The modification of peptidyl-histidine. (more detail) 9 NA Homo sapiens

GOA TAX020181 GO:0022417 biological process protein maturation by protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or mu (more detail) 9 NA Homo sapiens

GOA TAX031817 GO:1900112 biological process regulation of histone H3 K9 trimethylation Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation. (more detail) 9 NA Homo sapiens

GOA TAX031902 GO:1900247 biological process regulation of cytoplasmic translational elongation Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation. (more detail) 9 NA Homo sapiens

GOA TAX014916 GO:0004017 molecular function adenylate kinase activity Catalysis of the reaction: ATP + AMP = 2 ADP. (more detail) 9 NA Homo sapiens

GOA TAX028506 GO:0061614 biological process pri miRNA transcription by RNA polymerase II The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polyme (more detail) 9 NA Homo sapiens

GOA IEI002202 Protein protein interactors of human gene CDCA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDCA2 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI015393 Protein protein interactors of human gene ZNF143 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF143 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI003840 Protein protein interactors of human gene DUSP16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP16 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI011435 Protein protein interactors of human gene RNF26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF26 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI011553 Protein protein interactors of human gene RPLP0P6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPLP0P6 (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D IEI005972 Protein protein interactors of human gene HOXB13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXB13 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D TAX029193 GO:0070933 biological process histone H4 deacetylation The modification of histone H4 by the removal of one or more acetyl groups. (more detail) 9 NA Homo sapiens

GOA TAX022761 GO:0035197 molecular function siRNA binding Interacting selectively and non-covalently with a small interfering RNA, a 21-23 nucleotide RNA that (more detail) 9 NA Homo sapiens

GOA TAX022781 GO:0035252 molecular function UDP xylosyltransferase activity Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule. (more detail) 9 NA Homo sapiens

GOA TAX030711 GO:0097157 molecular function pre mRNA intronic binding Interacting selectively and non-covalently with an intronic sequence of a pre-messenger RNA (pre-mRN (more detail) 9 NA Homo sapiens

GOA TAX024563 GO:0043996 molecular function histone acetyltransferase activity (H4 K8 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acety (more detail) 9 NA Homo sapiens

GOA TAX019410 GO:0017151 molecular function DEAD/H box RNA helicase binding Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase. (more detail) 9 NA Homo sapiens

GOA TAX026609 GO:0050812 biological process regulation of acyl CoA biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 9 NA Homo sapiens

GOA TAX027070 GO:0051573 biological process negative regulation of histone H3 K9 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition (more detail) 9 NA Homo sapiens

GOA TAX027071 GO:0051574 biological process positive regulation of histone H3 K9 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a (more detail) 9 NA Homo sapiens

GOA TAX020953 GO:0031371 cellular component ubiquitin conjugating enzyme complex Any complex that possesses ubiquitin conjugating enzyme activity. (more detail) 9 NA Homo sapiens

GOA TAX020776 GO:0031053 biological process primary miRNA processing Any process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule (more detail) 9 NA Homo sapiens

GOA TAX025943 GO:0047498 molecular function calcium dependent phospholipase A2 activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. (more detail) 9 NA Homo sapiens

GOA TAX019916 GO:0020027 biological process hemoglobin metabolic process The chemical reactions and pathways involving hemoglobin, including its uptake and utilization. (more detail) 9 NA Homo sapiens

GOA TAX032253 GO:1901748 biological process leukotriene D4 metabolic process The chemical reactions and pathways involving leukotriene D4. (more detail) 9 NA Homo sapiens

GOA TAX033141 GO:1903800 biological process positive regulation of production of miRNAs involved in gene silencing by miRNA Any process that activates or increases the frequency, rate or extent of production of miRNAs involv (more detail) 9 NA Homo sapiens

GOA IEI009000 Protein protein interactors of human gene NPR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NPR1 (SwissProt ID=P (more detail) 9 17535438 Homo sapiens

I2D IEI004989 Protein protein interactors of human gene GAB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GAB3 (SwissProt ID=Q (more detail) 9 17535438 Homo sapiens

I2D IEI000385 Protein protein interactors of human gene AHCYL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AHCYL2 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI013995 Protein protein interactors of human gene TNFAIP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNFAIP2 (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D IEI000831 Protein protein interactors of human gene ARHGAP9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARHGAP9 (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D IEI000862 Protein protein interactors of human gene ARID3B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARID3B (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D TAX025597 GO:0046487 biological process glyoxylate metabolic process The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH. (more detail) 9 NA Homo sapiens

GOA TAX015321 GO:0004690 molecular function cyclic nucleotide dependent protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the pres (more detail) 9 NA Homo sapiens

GOA TAX034606 GO:2000320 biological process negative regulation of T helper 17 cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differ (more detail) 9 NA Homo sapiens

GOA IEI015204 Protein protein interactors of human gene ZBTB20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB20 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI009341 Protein protein interactors of human gene ORMDL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ORMDL3 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI004640 Protein protein interactors of human gene FBXO27 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO27 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI012933 Protein protein interactors of human gene SPSB4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPSB4 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI014806 Protein protein interactors of human gene USP9Y from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP9Y (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI003358 Protein protein interactors of human gene DCLRE1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCLRE1B (SwissProt I (more detail) 9 17535438 Homo sapiens

I2D IEI010256 Protein protein interactors of human gene POP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POP4 (SwissProt ID=O (more detail) 9 17535438 Homo sapiens

I2D IEI006174 Protein protein interactors of human gene IFI6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFI6 (SwissProt ID=P (more detail) 9 17535438 Homo sapiens

I2D IEI006261 Protein protein interactors of human gene IGLC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGLC1 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI000943 Protein protein interactors of human gene ASAH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASAH1 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D TAX017104 GO:0008174 molecular function mRNA methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in (more detail) 9 NA Homo sapiens

GOA TAX016855 GO:0007220 biological process Notch receptor processing The series of successive proteolytic cleavages of the Notch protein, which result in an active form (more detail) 9 NA Homo sapiens

GOA TAX024464 GO:0043596 cellular component nuclear replication fork The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA (more detail) 9 NA Homo sapiens

GOA TAX020600 GO:0030647 biological process aminoglycoside antibiotic metabolic process The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of (more detail) 9 NA Homo sapiens

GOA TAX026486 GO:0050650 biological process chondroitin sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, (more detail) 9 NA Homo sapiens

GOA TAX034836 GO:2000644 biological process regulation of receptor catabolic process Any process that modulates the frequency, rate or extent of receptor catabolic process. (more detail) 9 NA Homo sapiens

GOA TAX034550 GO:2000234 biological process positive regulation of rRNA processing Any process that activates or increases the frequency, rate or extent of rRNA processing. (more detail) 9 NA Homo sapiens

GOA TAX027915 GO:0060442 biological process branching involved in prostate gland morphogenesis The process in which the branching structure of the prostate gland is generated and organized. A bra (more detail) 9 NA Homo sapiens

GOA IEI014238 Protein protein interactors of human gene TRIM34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM34 (SwissProt ID (more detail) 9 17535438 Homo sapiens

I2D IEI014337 Protein protein interactors of human gene TRUB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRUB1 (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D IEI014360 Protein protein interactors of human gene TSKS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TSKS (SwissProt ID=Q (more detail) 9 17535438 Homo sapiens

I2D TAX023754 GO:0042285 molecular function xylosyltransferase activity Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate (more detail) 9 NA Homo sapiens

GOA TAX023789 GO:0042355 biological process L fucose catabolic process The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose). (more detail) 9 NA Homo sapiens

GOA TAX023856 GO:0042473 biological process outer ear morphogenesis The process in which the anatomical structures of the outer ear are generated and organized. The out (more detail) 9 NA Homo sapiens

GOA TAX022022 GO:0033182 biological process regulation of histone ubiquitination Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a h (more detail) 9 NA Homo sapiens

GOA TAX014994 GO:0004126 molecular function cytidine deaminase activity Catalysis of the reaction: cytidine + H2O = uridine + NH3. (more detail) 9 NA Homo sapiens

GOA TAX021477 GO:0032357 molecular function oxidized purine DNA binding Interacting selectively and non-covalently with oxidized purine residues in DNA. (more detail) 9 NA Homo sapiens

GOA TAX030481 GO:0090308 biological process regulation of methylation dependent chromatin silencing Any process that modulates the rate, frequency, or extent of the repression of transcription by meth (more detail) 9 NA Homo sapiens

GOA TAX019674 GO:0019317 biological process fucose catabolic process The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose). (more detail) 9 NA Homo sapiens

GOA TAX019765 GO:0019614 biological process catechol containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Cat (more detail) 9 NA Homo sapiens

GOA TAX021046 GO:0031545 molecular function peptidyl proline 4 dioxygenase activity Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-pro (more detail) 9 NA Homo sapiens

GOA TAX025617 GO:0046520 biological process sphingoid biosynthetic process The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of comp (more detail) 9 NA Homo sapiens

GOA TAX033553 GO:1904667 biological process negative regulation of ubiquitin protein ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligas (more detail) 9 NA Homo sapiens

GOA TAX034603 GO:2000317 biological process negative regulation of T helper 17 type immune response Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune (more detail) 9 NA Homo sapiens

GOA TAX028794 GO:0070199 biological process establishment of protein localization to chromosome The directed movement of a protein to a specific location on a chromosome. (more detail) 9 NA Homo sapiens

GOA IEI009677 Protein protein interactors of human gene PDE8A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDE8A (SwissProt ID= (more detail) 9 17535438 Homo sapiens

I2D MAX002047 Composition of the 2 MDa human PCAF complex. Transcription in eukaryotes is a tightly regulated, multistep process. Gene-specific transcriptional (more detail) 9 NA Homo sapiens

MSigDB MEX002218 Genes associated with Kinase Inhibitor BX 517 Genes associated with Kinase Inhibitor BX-517, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX001901 Genes associated with Kinase Inhibitor Kinome 709 Genes associated with Kinase Inhibitor Kinome_709, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MOX013420 Genes associated with Computational Drug Signature leucettamine B Genes associated with Computational Drug Signature leucettamine B, curated by the Drug Signature Dat (more detail) 9 25990557 Homo sapiens

DSigDB TAX014794 GO:0003810 molecular function protein glutamine gamma glutamyltransferase activity Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This re (more detail) 9 NA Homo sapiens

GOA TAX000735 Genes annotated by the GO term GO:0006354. The extension of an RNA molecule after transcription initiation by the addition of ribonucleotides catalyzed by an RNA polymerase. (more detail) 9 NA Homo sapiens

MSigDB MEX001433 Genes associated with Kinase Inhibitor S1107 Selleck Genes associated with Kinase Inhibitor S1107_Selleck, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens

DSigDB MEX001377 Genes associated with Kinase Inhibitor Kinome 468 Genes associated with Kinase Inhibitor Kinome_468, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX001403 Genes associated with Kinase Inhibitor NCGC00346961 01 Genes associated with Kinase Inhibitor NCGC00346961-01, curated by the Drug Signature Database (DSig (more detail) 9 25990557 Homo sapiens

DSigDB MEX001253 Genes associated with Kinase Inhibitor Kinome 242 Genes associated with Kinase Inhibitor Kinome_242, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX001260 Genes associated with Kinase Inhibitor Sunitinib Genes associated with Kinase Inhibitor Sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX001049 Genes associated with Approved Drug sunitinib malate Genes associated with Approved Drug sunitinib malate, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens

DSigDB MEX001071 Genes associated with Approved Drug belinostat Genes associated with Approved Drug belinostat, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX002310 Genes associated with Kinase Inhibitor Tozasertib Genes associated with Kinase Inhibitor Tozasertib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX002231 Genes associated with Kinase Inhibitor 1 NM PP1 Genes associated with Kinase Inhibitor 1-NM-PP1, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX002104 Genes associated with Kinase Inhibitor PF 477736 Genes associated with Kinase Inhibitor PF-477736, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MOX001818 Genes associated with Computational Drug Signature deferiprone Genes associated with Computational Drug Signature deferiprone, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens

DSigDB TAX016405 GO:0006538 biological process glutamate catabolic process The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopen (more detail) 9 NA Homo sapiens

GOA TAX013710 GO:0001574 biological process ganglioside biosynthetic process The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying (more detail) 9 NA Homo sapiens

GOA TAX015240 GO:0004579 molecular function dolichyl diphosphooligosaccharide protein glycotransferase activity Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl dipho (more detail) 9 NA Homo sapiens

GOA MOX012536 Genes associated with Computational Drug Signature Enzastaurin Genes associated with Computational Drug Signature Enzastaurin, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens

DSigDB MOX015634 Genes associated with Computational Drug Signature trimetrexate Genes associated with Computational Drug Signature trimetrexate, curated by the Drug Signature Datab (more detail) 9 25990557 Homo sapiens

DSigDB TAX016214 GO:0006265 biological process DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded D (more detail) 9 NA Homo sapiens

GOA TAX013597 GO:0001054 molecular function RNA polymerase I activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA (more detail) 9 NA Homo sapiens

GOA TAX014054 GO:0002084 biological process protein depalmitoylation The removal of palymitoyl groups from a lipoprotein. (more detail) 9 NA Homo sapiens

GOA PEX001484 Rhodanese: Rhodanese like domain Rhodanese has an internal duplication. This Pfam represents a single copy of this duplicated domain (more detail) 9 NA Homo sapiens

Pfam GEX000310 brain cancer brain cancer associated genes. PAGER constructed this gene set by grouping all genes which are assoc (more detail) 9 NA Homo sapiens

GAD FEX002392 MultipleMyeloma Gutierrez10 10genes Supplementary table 3: List of miRNA target genes which were significantly deregulated in the MM wit (more detail) 9 20054351 Homo sapiens

GeneSigDB TAX015856 GO:0005664 cellular component nuclear origin of replication recognition complex A multisubunit complex that is located at the replication origins of a chromosome in the nucleus. (more detail) 9 NA Homo sapiens

GOA WIG002010 Heme Biosynthesis Heme Biosynthesis (more detail) 9 NA Homo sapiens

WikiPathway TAX013431 GO:0000463 biological process maturation of LSU rRNA from tricistronic rRNA transcript (SSU rRNA, 5.8S rRNA, LSU rRNA) Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molec (more detail) 9 NA Homo sapiens

GOA WAG000648 alternative complement pathway The complement system of plasma proteins is an important part of the immune system that forms a casc (more detail) 9 NA Homo sapiens

BioCarta WAG001543 Pyrimidine biosynthesis (interconversion) (more detail) 9 NA Homo sapiens

Reactome WAG000297 NF kB is activated and signals survival (more detail) 9 NA Homo sapiens

Reactome WAG001367 Ribonucleotide salvage (more detail) 9 NA Homo sapiens

Reactome TAX001019 Genes annotated by the GO term GO:0008287. A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein. (more detail) 9 NA Homo sapiens

MSigDB WIG000856 Genes involved in G2/M DNA damage checkpoint (more detail) 9 NA Homo sapiens

MSigDB WIG001116 Genes involved in Purine ribonucleoside monophosphate biosynthesis (more detail) 9 NA Homo sapiens

MSigDB MEX001374 Genes associated with Kinase Inhibitor CHEMBL411903 Genes associated with Kinase Inhibitor CHEMBL411903, curated by the Drug Signature Database (DSigDB) (more detail) 9 25990557 Homo sapiens

DSigDB MEX001380 Genes associated with Kinase Inhibitor lfm a13 Genes associated with Kinase Inhibitor lfm-a13, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX001289 Genes associated with Kinase Inhibitor SU11274 Genes associated with Kinase Inhibitor SU11274, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX000496 Genes associated with Approved Drug amiloride hydrochloride Genes associated with Approved Drug amiloride hydrochloride, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens

DSigDB MEX001211 Genes associated with Kinase Inhibitor purvalanol A Genes associated with Kinase Inhibitor purvalanol A, curated by the Drug Signature Database (DSigDB) (more detail) 9 25990557 Homo sapiens

DSigDB MOX001487 Genes associated with Computational Drug Signature Dipentyl phthalate Genes associated with Computational Drug Signature Dipentyl phthalate, curated by the Drug Signature (more detail) 9 25990557 Homo sapiens

DSigDB MOX008615 Genes associated with Computational Drug Signature CHEMBL204357 Genes associated with Computational Drug Signature CHEMBL204357, curated by the Drug Signature Datab (more detail) 9 25990557 Homo sapiens

DSigDB TAX016294 GO:0006388 biological process tRNA splicing, via endonucleolytic cleavage and ligation Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' sp (more detail) 9 NA Homo sapiens

GOA TAX016157 GO:0006152 biological process purine nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family (more detail) 9 NA Homo sapiens

GOA WAG000332 mRNA Processing (more detail) 9 NA Homo sapiens

Reactome TAX000812 Genes annotated by the GO term GO:0030968. The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER related stress; results in changes in the regulation of transcription and translation. (more detail) 9 NA Homo sapiens

MSigDB MEX001449 Genes associated with Kinase Inhibitor CHEMBL47203 Genes associated with Kinase Inhibitor CHEMBL47203, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX001888 Genes associated with Kinase Inhibitor Oxindole Based Inhibitor 54 Genes associated with Kinase Inhibitor Oxindole-Based Inhibitor 54, curated by the Drug Signature Da (more detail) 9 25990557 Homo sapiens

DSigDB MEX002033 Genes associated with Kinase Inhibitor Sorafenib Genes associated with Kinase Inhibitor Sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX002191 Genes associated with Kinase Inhibitor CHEMBL241517 Genes associated with Kinase Inhibitor CHEMBL241517, curated by the Drug Signature Database (DSigDB) (more detail) 9 25990557 Homo sapiens

DSigDB MOX001876 Genes associated with Computational Drug Signature 2,2' Azobis(2 amidinopropane) Genes associated with Computational Drug Signature 2,2'-Azobis(2-amidinopropane), curated by the Dru (more detail) 9 25990557 Homo sapiens

DSigDB TAX013771 GO:0001682 biological process tRNA 5' leader removal Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P. (more detail) 9 NA Homo sapiens

GOA TAX014763 GO:0003691 molecular function double stranded telomeric DNA binding Interacting selectively and non-covalently with double-stranded telomere-associated DNA. (more detail) 9 NA Homo sapiens

GOA PEX002198 GST C 3: Glutathione S transferase, C terminal domain This domain is closely related to Pfam:PF00043. (more detail) 9 NA Homo sapiens

Pfam TAX016094 GO:0006048 biological process UDP N acetylglucosamine biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substan (more detail) 9 NA Homo sapiens

GOA PEX001840 EphA2 TM: Ephrin type A receptor 2 transmembrane domain Epha2_TM represents the left-handed dimer transmembrane domain of of EphA2 receptor. This domain ol (more detail) 9 NA Homo sapiens

Pfam MOX012197 Genes associated with Computational Drug Signature Debromohymenialdisine Genes associated with Computational Drug Signature Debromohymenialdisine, curated by the Drug Signat (more detail) 9 25990557 Homo sapiens

DSigDB MOX017130 Genes associated with Computational Drug Signature Ruxolitinib Genes associated with Computational Drug Signature Ruxolitinib, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens

DSigDB WAG001013 cyclin e destruction pathway Cyclins are proteins that associate with cyclin-dependent protein kises to regulate their activity a (more detail) 9 NA Homo sapiens

BioCarta FOX000822 Genes in the cancer module 65 (more detail) 9 NA Homo sapiens

MSigDB TAX000442 Genes annotated by the GO term GO:0009225. The chemical reactions and pathways involving nucleotide sugars, any nucleotide in which the distal phosphoric residue of a nucleoside 5' diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. (more detail) 9 NA Homo sapiens

MSigDB MEX001398 Genes associated with Kinase Inhibitor JNK Inhibitor V Genes associated with Kinase Inhibitor JNK Inhibitor V, curated by the Drug Signature Database (DSig (more detail) 9 25990557 Homo sapiens

DSigDB MEX000945 Genes associated with Approved Drug mycophenolate mofetil Genes associated with Approved Drug mycophenolate mofetil, curated by the Drug Signature Database (D (more detail) 9 25990557 Homo sapiens

DSigDB MEX001563 Genes associated with Kinase Inhibitor Kinome 2079 Genes associated with Kinase Inhibitor Kinome_2079, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX002121 Genes associated with Kinase Inhibitor CHEMBL2062937 Genes associated with Kinase Inhibitor CHEMBL2062937, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens

DSigDB MEX002183 Genes associated with Kinase Inhibitor PDGF Receptor Tyrosine Kinase Inhibitor V Genes associated with Kinase Inhibitor PDGF Receptor Tyrosine Kinase Inhibitor V, curated by the Dru (more detail) 9 25990557 Homo sapiens

DSigDB MOX005434 Genes associated with Computational Drug Signature 1 NM PP1 Genes associated with Computational Drug Signature 1-NM-PP1, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens

DSigDB MOX010669 Genes associated with Computational Drug Signature CHEMBL448246 Genes associated with Computational Drug Signature CHEMBL448246, curated by the Drug Signature Datab (more detail) 9 25990557 Homo sapiens

DSigDB FEX010108 hsa miR 518f 3p HITS-CLIP, Functional MTI (Weak) (more detail) 9 NA Homo sapiens

mirTARbase WAG000285 DNA strand elongation (more detail) 9 NA Homo sapiens

Reactome MAX000144 Set 'Core 9': 'embryonic stem cell' transcription regulators that are preferentially and coordinately overexpressed in the high grade, ER negative breast cancer tumors. Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear, howev (more detail) 9 NA Homo sapiens

MSigDB WIG001309 Genes involved in Tryptophan catabolism (more detail) 9 NA Homo sapiens

MSigDB TAX001384 Genes annotated by the GO term GO:0019783. Catalysis of the hydrolysis of various forms of polymeric ubiquitin or ubiquitin like sequences (e.g. APG8, ISG15, NEDD8, SUMO). Will remove ubiquitin like sequences from larger leaving groups. (more detail) 9 NA Homo sapiens

MSigDB MEX000935 Genes associated with Approved Drug amphotericin b Genes associated with Approved Drug amphotericin b, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX001887 Genes associated with Kinase Inhibitor aminopurvalanol A Genes associated with Kinase Inhibitor aminopurvalanol A, curated by the Drug Signature Database (DS (more detail) 9 25990557 Homo sapiens

DSigDB MEX001911 Genes associated with Kinase Inhibitor ML 9 Genes associated with Kinase Inhibitor ML-9, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX002119 Genes associated with Kinase Inhibitor GW809897X Genes associated with Kinase Inhibitor GW809897X, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX001793 Genes associated with Kinase Inhibitor CHEMBL1979577 Genes associated with Kinase Inhibitor CHEMBL1979577, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens

DSigDB MEX001823 Genes associated with Kinase Inhibitor GW843682X Genes associated with Kinase Inhibitor GW843682X, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX002147 Genes associated with Kinase Inhibitor CHEMBL1979883 Genes associated with Kinase Inhibitor CHEMBL1979883, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens

DSigDB MOX001810 Genes associated with Computational Drug Signature N Chlorothylnitrosourea sarcosinamide Genes associated with Computational Drug Signature N-Chlorothylnitrosourea sarcosinamide, curated by (more detail) 9 25990557 Homo sapiens

DSigDB MOX007345 Genes associated with Computational Drug Signature BMS 754807 Genes associated with Computational Drug Signature BMS-754807, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens

DSigDB TAX016398 GO:0006531 biological process aspartate metabolic process The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-ami (more detail) 9 NA Homo sapiens

GOA TAX016427 GO:0006560 biological process proline metabolic process The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyc (more detail) 9 NA Homo sapiens

GOA TAX016439 GO:0006573 biological process valine metabolic process The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid. (more detail) 9 NA Homo sapiens

GOA TAX016183 GO:0006198 biological process cAMP catabolic process The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, a (more detail) 9 NA Homo sapiens

GOA PEX001977 Peptidase C14: Caspase domain (more detail) 9 NA Homo sapiens

Pfam PEX002570 zf RING 2: Ring finger domain (more detail) 9 NA Homo sapiens

Pfam MOX017187 Genes associated with Computational Drug Signature keratan sulfate Genes associated with Computational Drug Signature keratan sulfate, curated by the Drug Signature Da (more detail) 9 25990557 Homo sapiens

DSigDB PEX001660 HECT: HECT domain (ubiquitin transferase) The name HECT comes from Homologous to the E6-AP Carboxyl Terminus. (more detail) 9 NA Homo sapiens

Pfam WAG000263 Ras signaling in the CD4+ TCR pathway (more detail) 9 NA Homo sapiens

NCI-Nature Curated WAG001258 regulation of splicing through sam68 While transcriptiol regulation is often viewed as the most prevalent way extracellular sigls to regu (more detail) 9 NA Homo sapiens

BioCarta WAG000888 Lagging Strand Synthesis (more detail) 9 NA Homo sapiens

Reactome MEX001372 Genes associated with Kinase Inhibitor Kinome 1335 Genes associated with Kinase Inhibitor Kinome_1335, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX001682 Genes associated with Kinase Inhibitor 7 Hydroxystaurosporine Genes associated with Kinase Inhibitor 7-Hydroxystaurosporine, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens

DSigDB MEX002068 Genes associated with Kinase Inhibitor BX 320 Genes associated with Kinase Inhibitor BX-320, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MOX000289 Genes associated with Computational Drug Signature Benzo[ghi]perylene Genes associated with Computational Drug Signature Benzo[ghi]perylene, curated by the Drug Signature (more detail) 9 25990557 Homo sapiens

DSigDB MOX002420 Genes associated with Computational Drug Signature Obacunone Genes associated with Computational Drug Signature Obacunone, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens

DSigDB MOX004598 Genes associated with Computational Drug Signature Pyocyanin Genes associated with Computational Drug Signature Pyocyanin, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens

DSigDB MOX004912 Genes associated with Computational Drug Signature MPTP Genes associated with Computational Drug Signature MPTP, curated by the Drug Signature Database (DSi (more detail) 9 25990557 Homo sapiens

DSigDB TAX013421 GO:0000447 biological process endonucleolytic cleavage in ITS1 to separate SSU rRNA from 5.8S rRNA and LSU rRNA from tricistronic rRNA transcript (SSU rRNA, 5.8S rRNA, LSU rRNA) Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produ (more detail) 9 NA Homo sapiens

GOA WAG001548 Telomere C strand (Lagging Strand) Synthesis (more detail) 9 NA Homo sapiens

Reactome FEX001569 Leukemia Andreeff08 09genes Supplementary Table 6 Genes associated with overall survival. (more detail) 9 18668134 Homo sapiens

GeneSigDB TAX001241 Genes annotated by the GO term GO:0004709. Catalysis of the phosphorylation and activation of MAP kinase kinases; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases. (more detail) 9 NA Homo sapiens

MSigDB TAX000764 Genes annotated by the GO term GO:0030148. The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long chain amine diol sphingosine or a closely related base (a sphingoid). (more detail) 9 NA Homo sapiens

MSigDB TAX000576 Genes annotated by the GO term GO:0006220. The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5' hydroxyl group of its glycose moiety. (more detail) 9 NA Homo sapiens

MSigDB MEX001354 Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX002000 Genes associated with Kinase Inhibitor CHEMBL1993941 Genes associated with Kinase Inhibitor CHEMBL1993941, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens

DSigDB MEX001691 Genes associated with Kinase Inhibitor Kinome 413 Genes associated with Kinase Inhibitor Kinome_413, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MEX002078 Genes associated with Kinase Inhibitor Kinome 2052 Genes associated with Kinase Inhibitor Kinome_2052, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens

DSigDB MOX003435 Genes associated with Computational Drug Signature 2,5 dimethylcelecoxib Genes associated with Computational Drug Signature 2,5-dimethylcelecoxib, curated by the Drug Signat (more detail) 9 25990557 Homo sapiens

DSigDB MOX004685 Genes associated with Computational Drug Signature STERIGMATOCYSTIN Genes associated with Computational Drug Signature STERIGMATOCYSTIN, curated by the Drug Signature D (more detail) 9 25990557 Homo sapiens

DSigDB MOX003187 Genes associated with Computational Drug Signature Deferasirox Genes associated with Computational Drug Signature Deferasirox, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens

DSigDB TAX013510 GO:0000808 cellular component origin recognition complex A multisubunit complex that is located at the replication origins of a chromosome. (more detail) 9 NA Homo sapiens

GOA WAG000293 Leading Strand Synthesis (more detail) 9 NA Homo sapiens

Reactome WAG001128 Processive synthesis on the lagging strand (more detail) 9 NA Homo sapiens

Reactome WAG001044 carm1 and regulation of the estrogen receptor Several forms of post-translatiol modification regulate protein activities. Recently, protein methy (more detail) 9 NA Homo sapiens

BioCarta WIG000327 Free Radical Induced Apoptosis Oxidative stress is one factor that can trigger programmed cell death. Activated neutrophils respond (more detail) 9 NA Homo sapiens

MSigDB TAX027767 GO:0060253 biological process negative regulation of glial cell proliferation Any process that stops or decreases the rate or extent of glial cell proliferation. (more detail) 14 NA Homo sapiens

GOA TAX032902 GO:1903350 biological process response to dopamine Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 14 NA Homo sapiens

GOA TAX032903 GO:1903351 biological process cellular response to dopamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 14 NA Homo sapiens

GOA TAX034813 GO:2000615 biological process regulation of histone H3 K9 acetylation Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation. (more detail) 14 NA Homo sapiens

GOA IEI011427 Protein protein interactors of human gene RNF213 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF213 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI006484 Protein protein interactors of human gene IRF2BP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IRF2BP2 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI007620 Protein protein interactors of human gene MAML3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAML3 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI003627 Protein protein interactors of human gene DNA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNA2 (SwissProt ID=P (more detail) 14 17535438 Homo sapiens

I2D IEI012190 Protein protein interactors of human gene SHOC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SHOC2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI001350 Protein protein interactors of human gene BIRC8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BIRC8 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX028736 GO:0070102 biological process interleukin 6 mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface (more detail) 14 NA Homo sapiens

GOA TAX030307 GO:0090069 biological process regulation of ribosome biogenesis Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis (more detail) 14 NA Homo sapiens

GOA IEI007125 Protein protein interactors of human gene LAMB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LAMB2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI008758 Protein protein interactors of human gene NEU1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NEU1 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI009052 Protein protein interactors of human gene NRF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NRF1 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI009158 Protein protein interactors of human gene NUFIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUFIP1 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI012228 Protein protein interactors of human gene SIPA1L1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIPA1L1 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI015377 Protein protein interactors of human gene ZNF106 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF106 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI002837 Protein protein interactors of human gene COMMD8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COMMD8 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI002929 Protein protein interactors of human gene CPNE6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CPNE6 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D IEI011282 Protein protein interactors of human gene RHOBTB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RHOBTB2 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI001550 Protein protein interactors of human gene C1D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C1D (SwissProt ID=Q1 (more detail) 14 17535438 Homo sapiens

I2D IEI004636 Protein protein interactors of human gene FBXO21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO21 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI012463 Protein protein interactors of human gene SLC39A7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC39A7 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI000372 Protein protein interactors of human gene AGR3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AGR3 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D IEI006862 Protein protein interactors of human gene KIR2DL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIR2DL4 (SwissProt I (more detail) 14 17535438 Homo sapiens

I2D IEI007892 Protein protein interactors of human gene MERTK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MERTK (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX018401 GO:0014857 biological process regulation of skeletal muscle cell proliferation Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. (more detail) 14 NA Homo sapiens

GOA TAX029906 GO:0072216 biological process positive regulation of metanephros development Any process that increases the rate, frequency or extent of metanephros development. Metanephros dev (more detail) 14 NA Homo sapiens

GOA IEI014220 Protein protein interactors of human gene TRIM15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM15 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D TAX021371 GO:0032183 molecular function SUMO binding Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO. (more detail) 14 NA Homo sapiens

GOA TAX025607 GO:0046500 biological process S adenosylmethionine metabolic process The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an (more detail) 14 NA Homo sapiens

GOA TAX028214 GO:0060967 biological process negative regulation of gene silencing by RNA Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing b (more detail) 14 NA Homo sapiens

GOA IEI008833 Protein protein interactors of human gene NIN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NIN (SwissProt ID=Q8 (more detail) 14 17535438 Homo sapiens

I2D IEI015250 Protein protein interactors of human gene ZC3H7B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZC3H7B (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI008538 Protein protein interactors of human gene NACA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NACA2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens

I2D TAX023209 GO:0036020 cellular component endolysosome membrane The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle forme (more detail) 14 NA Homo sapiens

GOA IEI001736 Protein protein interactors of human gene CALML3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CALML3 (SwissProt ID (more detail) 14 17535438 Homo sapiens

I2D IEI012606 Protein protein interactors of human gene SMC5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMC5 (SwissProt ID=Q (more detail) 14 17535438 Homo sapiens

I2D TAX027703 GO:0060149 biological process negative regulation of posttranscriptional gene silencing Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a (more detail) 14 NA Homo sapiens

GOA TAX021777 GO:0032785 biological process negative regulation of DNA templated transcription, elongation Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongati (more detail) 14 NA Homo sapiens

GOA MEX000897 Genes associated with Approved Drug sulindac Genes associated with Approved Drug sulindac, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB WIG001238 Genes involved in Spry regulation of FGF signaling (more detail) 14 NA Homo sapiens

MSigDB MOX010752 Genes associated with Computational Drug Signature CHEMBL460515 Genes associated with Computational Drug Signature CHEMBL460515, curated by the Drug Signature Datab (more detail) 14 25990557 Homo sapiens

DSigDB WAG001018 pten dependent cell cycle arrest and apoptosis PTEN is a tumor suppressor gene. Recombint PTEN is capable of dephosphorylating phosphatidylinositol (more detail) 14 NA Homo sapiens

BioCarta MOX017720 Genes associated with Computational Drug Signature LEVOSIMENDAN Genes associated with Computational Drug Signature LEVOSIMENDAN, curated by the Drug Signature Datab (more detail) 14 25990557 Homo sapiens

DSigDB TAX000200 Genes annotated by the GO term GO:0006984. Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation. (more detail) 14 NA Homo sapiens

MSigDB MEX000200 Genes associated with Approved Drug mefenamic acid Genes associated with Approved Drug mefenamic acid, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX018040 Genes associated with Computational Drug Signature VANADIUM Genes associated with Computational Drug Signature VANADIUM, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB WIG000611 Riboflavin metabolism (more detail) 14 NA Homo sapiens

MSigDB WAG000002 hypoxia inducible factor in the cardivascular system Hypoxia (or low O2 levels) affects various pathologies. First, tissue ischemia, a variation in O2 te (more detail) 14 NA Homo sapiens

BioCarta TAX000301 Genes annotated by the GO term GO:0030216. The process whereby a relatively unspecialized cell acquires specialized features of a keratinocyte. (more detail) 14 NA Homo sapiens

MSigDB WIG001058 Genes involved in p75NTR signals via NF kB (more detail) 14 NA Homo sapiens

MSigDB MOX004534 Genes associated with Computational Drug Signature Phylloquinone Genes associated with Computational Drug Signature Phylloquinone, curated by the Drug Signature Data (more detail) 14 25990557 Homo sapiens

DSigDB FEX000378 Breast Chinnaiyan06 71genes saha Table I. Consolidated List of Genes Demonstrating Significant Up-Regulation ( (more detail) 14 16152586 Homo sapiens

GeneSigDB FOX000721 Genes in the cancer module 429 (more detail) 14 NA Homo sapiens

MSigDB MEX000824 Genes associated with Approved Drug griseofulvin Genes associated with Approved Drug griseofulvin, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens

DSigDB MOX003817 Genes associated with Computational Drug Signature cephalothin Genes associated with Computational Drug Signature cephalothin, curated by the Drug Signature Databa (more detail) 14 25990557 Homo sapiens

DSigDB MOX016618 Genes associated with Computational Drug Signature bucladesine Genes associated with Computational Drug Signature bucladesine, curated by the Drug Signature Databa (more detail) 14 25990557 Homo sapiens

DSigDB MOX017039 Genes associated with Computational Drug Signature carbidopa Genes associated with Computational Drug Signature carbidopa, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB PEX001100 Myb DNA binding: Myb like DNA binding domain This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family 1. (more detail) 14 NA Homo sapiens

Pfam GEX000966 kidney transplant kidney transplant associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 14 NA Homo sapiens

GAD MOX001169 Genes associated with Computational Drug Signature pirarubicin Genes associated with Computational Drug Signature pirarubicin, curated by the Drug Signature Databa (more detail) 14 25990557 Homo sapiens

DSigDB MOX001245 Genes associated with Computational Drug Signature SODIUM CHROMATE Genes associated with Computational Drug Signature SODIUM CHROMATE, curated by the Drug Signature Da (more detail) 14 25990557 Homo sapiens

DSigDB MOX000003 Genes associated with Computational Drug Signature Alpinumisoflavone Genes associated with Computational Drug Signature Alpinumisoflavone, curated by the Drug Signature (more detail) 14 25990557 Homo sapiens

DSigDB MOX016497 Genes associated with Computational Drug Signature 4,5,6,7 tetrabromobenzotriazole Genes associated with Computational Drug Signature 4,5,6,7-tetrabromobenzotriazole, curated by the D (more detail) 14 25990557 Homo sapiens

DSigDB WIG001769 Base Excision Repair Pathway Base Excision Repair Pathway (more detail) 14 NA Homo sapiens

Protein Lounge MOX004317 Genes associated with Computational Drug Signature mestranol Genes associated with Computational Drug Signature mestranol, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens

DSigDB IEI015018 Protein protein interactors of human gene WDR62 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR62 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI003228 Protein protein interactors of human gene CYP17A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CYP17A1 (SwissProt I (more detail) 16 17535438 Homo sapiens

I2D IEI011653 Protein protein interactors of human gene RSF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RSF1 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D TAX020422 GO:0030275 molecular function LRR domain binding Interacting selectively and non-covalently with a LRR domain (leucine rich repeats) of a protein. (more detail) 16 NA Homo sapiens

GOA IEI007673 Protein protein interactors of human gene MAP4K2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP4K2 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI007780 Protein protein interactors of human gene MCAT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MCAT (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI001539 Protein protein interactors of human gene C18orf25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene C18orf25 (SwissProt (more detail) 16 17535438 Homo sapiens

I2D TAX031572 GO:0106058 biological process positive regulation of calcineurin mediated signaling Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signal (more detail) 16 NA Homo sapiens

GOA IEI002044 Protein protein interactors of human gene CCNE2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCNE2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI002462 Protein protein interactors of human gene CHD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD2 (SwissProt ID=O (more detail) 16 17535438 Homo sapiens

I2D TAX021922 GO:0033002 biological process muscle cell proliferation The expansion of a muscle cell population by cell division. (more detail) 16 NA Homo sapiens

GOA TAX034418 GO:2000001 biological process regulation of DNA damage checkpoint Any process that modulates the frequency, rate or extent of a DNA damage checkpoint. (more detail) 16 NA Homo sapiens

GOA IEI009253 Protein protein interactors of human gene OGFR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OGFR (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI003834 Protein protein interactors of human gene DUSP10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP10 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX026778 GO:0051081 biological process nuclear envelope disassembly The controlled breakdown of the nuclear envelope in the context of a normal process. (more detail) 16 NA Homo sapiens

GOA TAX020501 GO:0030397 biological process membrane disassembly The controlled breakdown of any cell membrane in the context of a normal process such as autophagy. (more detail) 16 NA Homo sapiens

GOA IEI001724 Protein protein interactors of human gene CADPS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CADPS2 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI006347 Protein protein interactors of human gene IL32 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL32 (SwissProt ID=P (more detail) 16 17535438 Homo sapiens

I2D IEI014284 Protein protein interactors of human gene TRIP11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIP11 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX020039 GO:0021772 biological process olfactory bulb development The progression of the olfactory bulb over time from its initial formation until its mature state. T (more detail) 16 NA Homo sapiens

GOA IEI002979 Protein protein interactors of human gene CRELD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CRELD1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI004015 Protein protein interactors of human gene EID2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EID2 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens

I2D IEI004409 Protein protein interactors of human gene FABP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FABP4 (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D IEI014217 Protein protein interactors of human gene TRIM11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM11 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI002803 Protein protein interactors of human gene COL3A1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COL3A1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI003479 Protein protein interactors of human gene DENR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DENR (SwissProt ID=O (more detail) 16 17535438 Homo sapiens

I2D TAX029165 GO:0070886 biological process positive regulation of calcineurin NFAT signaling cascade Any process that activates or increases the frequency, rate or extent of signaling via the calcineur (more detail) 16 NA Homo sapiens

GOA TAX017087 GO:0008143 molecular function poly(A) binding Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, (more detail) 16 NA Homo sapiens

GOA TAX025589 GO:0046475 biological process glycerophospholipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivati (more detail) 16 NA Homo sapiens

GOA IEI008742 Protein protein interactors of human gene NELFA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NELFA (SwissProt ID= (more detail) 16 17535438 Homo sapiens

I2D TAX022164 GO:0033599 biological process regulation of mammary gland epithelial cell proliferation Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferat (more detail) 16 NA Homo sapiens

GOA TAX030665 GO:0097067 biological process cellular response to thyroid hormone stimulus A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene ex (more detail) 16 NA Homo sapiens

GOA TAX026163 GO:0048384 biological process retinoic acid receptor signaling pathway The series of molecular signals generated as a consequence of a retinoic acid receptor binding to on (more detail) 16 NA Homo sapiens

GOA TAX026834 GO:0051151 biological process negative regulation of smooth muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell dif (more detail) 16 NA Homo sapiens

GOA IEI015567 Protein protein interactors of human gene ZNF473 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF473 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D IEI009974 Protein protein interactors of human gene PIWIL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIWIL1 (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D TAX030707 GO:0097153 molecular function cysteine type endopeptidase activity involved in apoptotic process Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism i (more detail) 16 NA Homo sapiens

GOA IEI002589 Protein protein interactors of human gene CLASRP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CLASRP (SwissProt ID (more detail) 16 17535438 Homo sapiens

I2D WIG000423 Acetylation and Deacetylation of RelA in The Nucleus (more detail) 16 NA Homo sapiens

MSigDB WAG000003 alk in cardiac myocytes Heart formation is cued by a combition of positive and negative sigls from surrounding tissues. Inh (more detail) 16 NA Homo sapiens

BioCarta TAX000127 Genes annotated by the GO term GO:0031497. The assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. (more detail) 16 NA Homo sapiens

MSigDB WIG001926 IL 9 signaling pathway IL-9 signaling pathway (more detail) 16 NA Homo sapiens

WikiPathway MOX004031 Genes associated with Computational Drug Signature dydrogesterone Genes associated with Computational Drug Signature dydrogesterone, curated by the Drug Signature Dat (more detail) 16 25990557 Homo sapiens

DSigDB MOX004259 Genes associated with Computational Drug Signature levamisole Genes associated with Computational Drug Signature levamisole, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens

DSigDB MOX002190 Genes associated with Computational Drug Signature Isoorientin Genes associated with Computational Drug Signature Isoorientin, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB MOX002326 Genes associated with Computational Drug Signature KN 62 Genes associated with Computational Drug Signature KN-62, curated by the Drug Signature Database (DS (more detail) 16 25990557 Homo sapiens

DSigDB MOX015609 Genes associated with Computational Drug Signature triamcinolone Genes associated with Computational Drug Signature triamcinolone, curated by the Drug Signature Data (more detail) 16 25990557 Homo sapiens

DSigDB FOX000732 Genes in the cancer module 444 (more detail) 16 NA Homo sapiens

MSigDB MOX001610 Genes associated with Computational Drug Signature PK 11195 Genes associated with Computational Drug Signature PK 11195, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB MOX005136 Genes associated with Computational Drug Signature Ethene Genes associated with Computational Drug Signature Ethene, curated by the Drug Signature Database (D (more detail) 16 25990557 Homo sapiens

DSigDB MAX002760 High level amplifications detected in oral squamous cell carcinoma (OSCC) lines by array CGH analysis. Array-based comparative genomic hybridization (array-CGH) has good potential for the high-throughput (more detail) 16 NA Homo sapiens

MSigDB MEX000196 Genes associated with Approved Drug mebendazole Genes associated with Approved Drug mebendazole, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens

DSigDB MOX001007 Genes associated with Computational Drug Signature Brassinolide Genes associated with Computational Drug Signature Brassinolide, curated by the Drug Signature Datab (more detail) 16 25990557 Homo sapiens

DSigDB MOX003367 Genes associated with Computational Drug Signature Lapatinib Genes associated with Computational Drug Signature Lapatinib, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB MAX000730 Cluster 6: selected luminal genes clustered together across breast cancer samples. Previous microarray studies on breast cancer identified multiple tumour classes, of which the most p (more detail) 16 NA Homo sapiens

MSigDB WIG000268 B Cell Survival Pathway Physical interactions between intergrin alpha4beta1 heterodimer expressed on B cells and counter rec (more detail) 16 NA Homo sapiens

MSigDB MOX000590 Genes associated with Computational Drug Signature Mevastatin Genes associated with Computational Drug Signature Mevastatin, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens

DSigDB MOX004758 Genes associated with Computational Drug Signature thymidine Genes associated with Computational Drug Signature thymidine, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens

DSigDB MAX003181 Genes down regulated by expression of HBV X protein (HBVgp3) [GeneID=944566] in primary hepatocytes. Hepatitis B virus (HBV) is a major risk factor for the development of hepatocellular carcinoma (HCC) (more detail) 16 NA Homo sapiens

MSigDB MOX001547 Genes associated with Computational Drug Signature trequinsin Genes associated with Computational Drug Signature trequinsin, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens

DSigDB MOX007183 Genes associated with Computational Drug Signature bay 11 7082 Genes associated with Computational Drug Signature bay 11-7082, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens

DSigDB MOX013565 Genes associated with Computational Drug Signature Mangiferin Genes associated with Computational Drug Signature Mangiferin, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens

DSigDB TAX016261 GO:0006337 biological process nucleosome disassembly The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin compo (more detail) 16 NA Homo sapiens

GOA MOX015798 Genes associated with Computational Drug Signature Ursolic acid Genes associated with Computational Drug Signature Ursolic acid, curated by the Drug Signature Datab (more detail) 16 25990557 Homo sapiens

DSigDB WAG000249 chromatin remodeling by hswi/snf atp dependent complexes The eukaryotic genome is packaged by histone and nonhistone proteins to form chromatin. The assembly (more detail) 16 NA Homo sapiens

BioCarta FEX002338 Lymphoma Germinal07 18genes Table S10. Gene expression values of the main regulatory network distinguishing ABC and GCB (more detail) 16 19455257 Homo sapiens

GeneSigDB IEI004678 Protein protein interactors of human gene FCGR2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FCGR2A (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D TAX033039 GO:1903599 biological process positive regulation of autophagy of mitochondrion Any process that activates or increases the frequency, rate or extent of mitochondrion degradation b (more detail) 18 NA Homo sapiens

GOA TAX019933 GO:0021522 biological process spinal cord motor neuron differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural (more detail) 18 NA Homo sapiens

GOA IEI010741 Protein protein interactors of human gene PTPN4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTPN4 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI005281 Protein protein interactors of human gene GMDS from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GMDS (SwissProt ID=O (more detail) 18 17535438 Homo sapiens

I2D TAX029158 GO:0070875 biological process positive regulation of glycogen metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 18 NA Homo sapiens

GOA TAX022758 GO:0035194 biological process posttranscriptional gene silencing by RNA Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules tha (more detail) 18 NA Homo sapiens

GOA IEI013129 Protein protein interactors of human gene STK38L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STK38L (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D TAX021274 GO:0031998 biological process regulation of fatty acid beta oxidation Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation. (more detail) 18 NA Homo sapiens

GOA IEI008333 Protein protein interactors of human gene MTHFD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MTHFD2 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI014815 Protein protein interactors of human gene UTP20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UTP20 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI009138 Protein protein interactors of human gene NUDT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NUDT1 (SwissProt ID= (more detail) 18 17535438 Homo sapiens

I2D IEI008581 Protein protein interactors of human gene NAT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NAT2 (SwissProt ID=P (more detail) 18 17535438 Homo sapiens

I2D TAX029506 GO:0071498 biological process cellular response to fluid shear stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 18 NA Homo sapiens

GOA IEI003554 Protein protein interactors of human gene DIAPH3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIAPH3 (SwissProt ID (more detail) 18 17535438 Homo sapiens

I2D IEI004576 Protein protein interactors of human gene FAR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAR1 (SwissProt ID=Q (more detail) 18 17535438 Homo sapiens

I2D MOX005034 Genes associated with Computational Drug Signature SAQUINAVIR Genes associated with Computational Drug Signature SAQUINAVIR, curated by the Drug Signature Databas (more detail) 18 25990557 Homo sapiens

DSigDB MOX018063 Genes associated with Computational Drug Signature AlphaRedisol Genes associated with Computational Drug Signature AlphaRedisol, curated by the Drug Signature Datab (more detail) 18 25990557 Homo sapiens

DSigDB WIG000789 Genes involved in Deadenylation of mRNA (more detail) 18 NA Homo sapiens

MSigDB MOX004076 Genes associated with Computational Drug Signature N ethylmaleimide Genes associated with Computational Drug Signature N-ethylmaleimide, curated by the Drug Signature D (more detail) 18 25990557 Homo sapiens

DSigDB MOX016920 Genes associated with Computational Drug Signature fenbendazole Genes associated with Computational Drug Signature fenbendazole, curated by the Drug Signature Datab (more detail) 18 25990557 Homo sapiens

DSigDB TAX000805 Genes annotated by the GO term GO:0035295. The process whose specific outcome is the progression of a tube over time, from its intial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary genital tracts. (more detail) 18 NA Homo sapiens

MSigDB MOX017591 Genes associated with Computational Drug Signature pyrimethamine Genes associated with Computational Drug Signature pyrimethamine, curated by the Drug Signature Data (more detail) 18 25990557 Homo sapiens

DSigDB MOX002430 Genes associated with Computational Drug Signature selenium(6+) Genes associated with Computational Drug Signature selenium(6+), curated by the Drug Signature Datab (more detail) 18 25990557 Homo sapiens

DSigDB MOX004292 Genes associated with Computational Drug Signature mechlorethamine Genes associated with Computational Drug Signature mechlorethamine, curated by the Drug Signature Da (more detail) 18 25990557 Homo sapiens

DSigDB MOX000334 Genes associated with Computational Drug Signature ERIODICTYOL Genes associated with Computational Drug Signature ERIODICTYOL, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens

DSigDB MEX000802 Genes associated with Approved Drug lapatinib Genes associated with Approved Drug lapatinib, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens

DSigDB WIG001120 Genes involved in Pyruvate metabolism (more detail) 18 NA Homo sapiens

MSigDB TAX000389 Genes annotated by the GO term GO:0051053. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. (more detail) 18 NA Homo sapiens

MSigDB TAX000011 Genes annotated by the GO term GO:0051092. Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF kappaB. (more detail) 18 NA Homo sapiens

MSigDB FEX001628 Leukemia Ueno09 26genes Table 2. Changes in cell cycle-related genes after PU.1 induction (more detail) 18 19749795 Homo sapiens

GeneSigDB FEX001952 Lung Chitale09 25genes KRAS Table 1b. KRAS expression profiles (more detail) 18 19525976 Homo sapiens

GeneSigDB FEX002371 MesenchymalStemCells Rider08 21genes Table 1. Stem cell self-renewal and maintenance gene expression in bone marrow-derived mesenchymal s (more detail) 18 18356575 Homo sapiens

GeneSigDB MOX017486 Genes associated with Computational Drug Signature Congo red Genes associated with Computational Drug Signature Congo red, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens

DSigDB MAX001433 Genes from the 12p region that were up regulated in yolk sac tumor cells compared to normal testis. Adult male germ cell tumors (GCTs) comprise distinct groups: seminomas and nonseminomas, which inclu (more detail) 18 NA Homo sapiens

MSigDB MOX004764 Genes associated with Computational Drug Signature ticlopidine Genes associated with Computational Drug Signature ticlopidine, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens

DSigDB WIG000433 Sprouty regulation of tyrosine kinase signals Four different members of the Sprouty protein family block the cellular proliferation and differenti (more detail) 18 NA Homo sapiens

MSigDB FEX001484 Leukemia Li07 19genes Supplementary Table1d Genes over-expressed in the highest PKC-? expressing (quartile 4) DLBCL patien (more detail) 18 17313671 Homo sapiens

GeneSigDB TAX000119 Genes annotated by the GO term GO:0006921. The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. (more detail) 18 NA Homo sapiens

MSigDB WIG002041 Serotonin Receptor 4/6/7 and NR3C Signaling Serotonin Receptor 4/6/7 and NR3C Signaling (more detail) 18 NA Homo sapiens

WikiPathway IEI002293 Protein protein interactors of human gene CDX2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDX2 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI014318 Protein protein interactors of human gene TRPC4AP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRPC4AP (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D IEI009856 Protein protein interactors of human gene PHIP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHIP (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI006576 Protein protein interactors of human gene IWS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IWS1 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI007289 Protein protein interactors of human gene LIN9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LIN9 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI015367 Protein protein interactors of human gene ZMYM4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZMYM4 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI011493 Protein protein interactors of human gene RPF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPF2 (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D TAX029371 GO:0071295 biological process cellular response to vitamin Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 20 NA Homo sapiens

GOA TAX016789 GO:0007130 biological process synaptonemal complex assembly The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds p (more detail) 20 NA Homo sapiens

GOA IEI000995 Protein protein interactors of human gene ASPSCR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ASPSCR1 (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D TAX029312 GO:0071173 biological process spindle assembly checkpoint A cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly (more detail) 20 NA Homo sapiens

GOA IEI007602 Protein protein interactors of human gene MAGEH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAGEH1 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI013434 Protein protein interactors of human gene TBCA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBCA (SwissProt ID=Q (more detail) 20 17535438 Homo sapiens

I2D IEI009345 Protein protein interactors of human gene OSBPL10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OSBPL10 (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D IEI010920 Protein protein interactors of human gene RABGGTB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RABGGTB (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D IEI011831 Protein protein interactors of human gene SCAND1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCAND1 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI011307 Protein protein interactors of human gene RIDA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RIDA (SwissProt ID=P (more detail) 20 17535438 Homo sapiens

I2D IEI010328 Protein protein interactors of human gene PPM1F from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPM1F (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI015647 Protein protein interactors of human gene ZNF593 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF593 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D TAX029313 GO:0071174 biological process mitotic spindle checkpoint A mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase t (more detail) 20 NA Homo sapiens

GOA TAX016874 GO:0007263 biological process nitric oxide mediated signal transduction Any intracellular signal transduction in which the signal is passed on within the cell via nitric ox (more detail) 20 NA Homo sapiens

GOA IEI000889 Protein protein interactors of human gene ARL6IP5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARL6IP5 (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D TAX032403 GO:1902176 biological process negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-ind (more detail) 20 NA Homo sapiens

GOA IEI001959 Protein protein interactors of human gene CCDC59 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CCDC59 (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI002134 Protein protein interactors of human gene CD40LG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CD40LG (SwissProt ID (more detail) 20 17535438 Homo sapiens

I2D IEI002243 Protein protein interactors of human gene CDK14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK14 (SwissProt ID= (more detail) 20 17535438 Homo sapiens

I2D IEI002252 Protein protein interactors of human gene CDK2AP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDK2AP2 (SwissProt I (more detail) 20 17535438 Homo sapiens

I2D IEI005176 Protein protein interactors of human gene GGH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GGH (SwissProt ID=Q9 (more detail) 20 17535438 Homo sapiens

I2D TAX016779 GO:0007094 biological process mitotic spindle assembly checkpoint A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division (more detail) 20 NA Homo sapiens

GOA GEX001252 overall effect overall effect associated genes. PAGER constructed this gene set by grouping all genes which are ass (more detail) 20 NA Homo sapiens

GAD WIG000332 Corticosteroids and cardioprotection Myocardial infarction damages heart tissue both during the initial ischemia and the subsequent reper (more detail) 20 NA Homo sapiens

MSigDB MOX003189 Genes associated with Computational Drug Signature 2,2',4,6,6' pentachlorobiphenyl Genes associated with Computational Drug Signature 2,2',4,6,6'-pentachlorobiphenyl, curated by the D (more detail) 20 25990557 Homo sapiens

DSigDB WAG001224 Alkaloid biosynthesis II (more detail) 20 NA Homo sapiens

KEGG MOX017938 Genes associated with Computational Drug Signature tolfenamic acid Genes associated with Computational Drug Signature tolfenamic acid, curated by the Drug Signature Da (more detail) 20 25990557 Homo sapiens

DSigDB WIG001405 ACE Inhibitor Pathway, Pharmacodynamics Model, non-tissue-specific cell displaying genes which may be involved in the ACE inhibitor pathway (more detail) 20 NA Homo sapiens

PharmGKB WIG001359 Agents Acting on the Renin Angiotensin System Pathway, Pharmacodynamics Genes involved in the pharmacodynamics of the drugs that act on the renin-angiotensin-aldosterone sy (more detail) 20 NA Homo sapiens

PharmGKB MOX003197 Genes associated with Computational Drug Signature 1,3,5 Tris(4 hydroxyphenyl) 4 propyl 1H pyrazole Genes associated with Computational Drug Signature 1,3,5-Tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole, (more detail) 20 25990557 Homo sapiens

DSigDB MOX017695 Genes associated with Computational Drug Signature sulpiride Genes associated with Computational Drug Signature sulpiride, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB GEX000989 leukemia leukemia associated genes. PAGER constructed this gene set by grouping all genes which are associate (more detail) 20 NA Homo sapiens

GAD MAX000390 Genes up regulated in K562 cells (chronic myelogenous leukemia, CML) expressing TP53 and MYC [GeneID=7157;4609]. We have previously demonstrated that c-Myc impairs p53-mediated apoptosis in K562 human leukemia cel (more detail) 20 NA Homo sapiens

MSigDB GEX000631 endometrial cancer endometrial cancer associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 20 NA Homo sapiens

GAD MOX016811 Genes associated with Computational Drug Signature Eplerenone Genes associated with Computational Drug Signature Eplerenone, curated by the Drug Signature Databas (more detail) 20 25990557 Homo sapiens

DSigDB FEX000500 Breast Ma07 28genes recurrence Table 1. The 28-gene signature for breast cancer recurrent and metastatic potential (more detail) 20 17404081 Homo sapiens

GeneSigDB MOX002517 Genes associated with Computational Drug Signature Teriflunomide Genes associated with Computational Drug Signature Teriflunomide, curated by the Drug Signature Data (more detail) 20 25990557 Homo sapiens

DSigDB MOX012163 Genes associated with Computational Drug Signature daidzein Genes associated with Computational Drug Signature daidzein, curated by the Drug Signature Database (more detail) 20 25990557 Homo sapiens

DSigDB IEI014638 Protein protein interactors of human gene UBXN8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBXN8 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D TAX020932 GO:0031332 cellular component RNAi effector complex Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most kno (more detail) 11 NA Homo sapiens

GOA IEI015481 Protein protein interactors of human gene ZNF318 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF318 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI015751 Protein protein interactors of human gene ZNF76 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF76 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI002825 Protein protein interactors of human gene COLGALT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COLGALT1 (SwissProt (more detail) 11 17535438 Homo sapiens

I2D IEI011813 Protein protein interactors of human gene SBF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SBF1 (SwissProt ID=O (more detail) 11 17535438 Homo sapiens

I2D IEI012721 Protein protein interactors of human gene SNX19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SNX19 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI012890 Protein protein interactors of human gene SPINT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPINT2 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI006515 Protein protein interactors of human gene ISY1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ISY1 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D TAX017216 GO:0008349 molecular function MAP kinase kinase kinase kinase activity Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kin (more detail) 11 NA Homo sapiens

GOA TAX017016 GO:0008020 molecular function G protein coupled photoreceptor activity Combining with incidental electromagnetic radiation, particularly visible light, and transmitting th (more detail) 11 NA Homo sapiens

GOA IEI003899 Protein protein interactors of human gene EAF2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EAF2 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI012041 Protein protein interactors of human gene SERPINC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SERPINC1 (SwissProt (more detail) 11 17535438 Homo sapiens

I2D IEI006257 Protein protein interactors of human gene IGKC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IGKC (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D IEI000145 Protein protein interactors of human gene ACOT8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACOT8 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI014428 Protein protein interactors of human gene TTC37 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTC37 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D TAX025327 GO:0045899 biological process positive regulation of RNA polymerase II transcriptional preinitiation complex assembly Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcrip (more detail) 11 NA Homo sapiens

GOA IEI000738 Protein protein interactors of human gene APOBEC3C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APOBEC3C (SwissProt (more detail) 11 17535438 Homo sapiens

I2D IEI014439 Protein protein interactors of human gene TTF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TTF1 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D TAX025365 GO:0045945 biological process positive regulation of transcription by RNA polymerase III Any process that activates or increases the frequency, rate or extent of transcription mediated by R (more detail) 11 NA Homo sapiens

GOA TAX014907 GO:0004000 molecular function adenosine deaminase activity Catalysis of the reaction: adenosine + H2O = inosine + NH3. (more detail) 11 NA Homo sapiens

GOA IEI002171 Protein protein interactors of human gene CDC14A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC14A (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D TAX016714 GO:0006983 biological process ER overload response The series of molecular signals generated by the accumulation of normal or misfolded proteins in the (more detail) 11 NA Homo sapiens

GOA TAX030895 GO:0097504 cellular component Gemini of coiled bodies Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or C (more detail) 11 NA Homo sapiens

GOA TAX024446 GO:0043560 molecular function insulin receptor substrate binding Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins (more detail) 11 NA Homo sapiens

GOA TAX020664 GO:0030850 biological process prostate gland development The process whose specific outcome is the progression of the prostate gland over time, from its form (more detail) 11 NA Homo sapiens

GOA TAX026404 GO:0050072 molecular function m7G(5')pppN diphosphatase activity Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosi (more detail) 11 NA Homo sapiens

GOA TAX031808 GO:1900102 biological process negative regulation of endoplasmic reticulum unfolded protein response Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum u (more detail) 11 NA Homo sapiens

GOA IEI003747 Protein protein interactors of human gene DPH1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DPH1 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI011384 Protein protein interactors of human gene RNF122 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF122 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI005113 Protein protein interactors of human gene GCLC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GCLC (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D IEI012617 Protein protein interactors of human gene SMG7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMG7 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI006345 Protein protein interactors of human gene IL3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IL3 (SwissProt ID=P0 (more detail) 11 17535438 Homo sapiens

I2D TAX025299 GO:0045835 biological process negative regulation of meiotic nuclear division Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. (more detail) 11 NA Homo sapiens

GOA TAX021010 GO:0031462 cellular component Cul2 RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form (more detail) 11 NA Homo sapiens

GOA IEI003855 Protein protein interactors of human gene DUSP9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP9 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI015227 Protein protein interactors of human gene ZBTB5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZBTB5 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI015358 Protein protein interactors of human gene ZMAT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZMAT3 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI015424 Protein protein interactors of human gene ZNF217 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF217 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI015495 Protein protein interactors of human gene ZNF335 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF335 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI009992 Protein protein interactors of human gene PKMYT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PKMYT1 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI010773 Protein protein interactors of human gene PTX3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTX3 (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D IEI004684 Protein protein interactors of human gene FCHO1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FCHO1 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI011379 Protein protein interactors of human gene RNF113A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF113A (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D IEI011431 Protein protein interactors of human gene RNF220 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF220 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI011771 Protein protein interactors of human gene SALL2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SALL2 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI006961 Protein protein interactors of human gene KLK9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLK9 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI009951 Protein protein interactors of human gene PIP4K2A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIP4K2A (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D IEI014070 Protein protein interactors of human gene TOB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TOB2 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI000846 Protein protein interactors of human gene ARHGEF25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARHGEF25 (SwissProt (more detail) 11 17535438 Homo sapiens

I2D IEI007468 Protein protein interactors of human gene LSM11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LSM11 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI008103 Protein protein interactors of human gene MOK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MOK (SwissProt ID=Q9 (more detail) 11 17535438 Homo sapiens

I2D IEI008397 Protein protein interactors of human gene MVK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MVK (SwissProt ID=Q0 (more detail) 11 17535438 Homo sapiens

I2D TAX019028 GO:0016442 cellular component RISC complex A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfe (more detail) 11 NA Homo sapiens

GOA IEI006204 Protein protein interactors of human gene IFRD1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene IFRD1 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI006947 Protein protein interactors of human gene KLHL8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHL8 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI013856 Protein protein interactors of human gene TMEM165 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TMEM165 (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D TAX019363 GO:0017070 molecular function U6 snRNA binding Interacting selectively and non-covalently with the U6 small nuclear RNA (U6 snRNA). (more detail) 11 NA Homo sapiens

GOA TAX027085 GO:0051593 biological process response to folic acid Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 11 NA Homo sapiens

GOA IEI008939 Protein protein interactors of human gene NOMO2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOMO2 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D TAX024380 GO:0043471 biological process regulation of cellular carbohydrate catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways res (more detail) 11 NA Homo sapiens

GOA TAX025534 GO:0046349 biological process amino sugar biosynthetic process The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing (more detail) 11 NA Homo sapiens

GOA IEI002466 Protein protein interactors of human gene CHD6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHD6 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI009220 Protein protein interactors of human gene OAZ1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OAZ1 (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D IEI003574 Protein protein interactors of human gene DIXDC1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIXDC1 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI003603 Protein protein interactors of human gene DLX5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DLX5 (SwissProt ID=P (more detail) 11 17535438 Homo sapiens

I2D WEX000100 TH9 Differentiation The genes related to th9 differentiation (adaptive immunity) in immune using next-generation sequenc (more detail) 11 NA Homo sapiens

GeoMx Cancer Transcriptome Atlas IEI006141 Protein protein interactors of human gene ICE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ICE1 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D TAX028917 GO:0070411 molecular function I SMAD binding Interacting selectively and non-covalently with an inhibitory SMAD signaling protein. (more detail) 11 NA Homo sapiens

GOA TAX025031 GO:0045240 cellular component dihydrolipoyl dehydrogenase complex A protein complex that possesses alpha-ketoglutarate dehydrogenase activity. (more detail) 11 NA Homo sapiens

GOA TAX024476 GO:0043619 biological process regulation of transcription from RNA polymerase II promoter in response to oxidative stress Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a (more detail) 11 NA Homo sapiens

GOA TAX026315 GO:0048715 biological process negative regulation of oligodendrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differ (more detail) 11 NA Homo sapiens

GOA IEI003331 Protein protein interactors of human gene DCAF13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCAF13 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI003333 Protein protein interactors of human gene DCAF16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCAF16 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D IEI009828 Protein protein interactors of human gene PHACTR4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHACTR4 (SwissProt I (more detail) 11 17535438 Homo sapiens

I2D IEI011134 Protein protein interactors of human gene RCL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RCL1 (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens

I2D IEI005986 Protein protein interactors of human gene HOXC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HOXC6 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI012932 Protein protein interactors of human gene SPSB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SPSB3 (SwissProt ID= (more detail) 11 17535438 Homo sapiens

I2D IEI014204 Protein protein interactors of human gene TRERF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRERF1 (SwissProt ID (more detail) 11 17535438 Homo sapiens

I2D TAX019270 GO:0016868 molecular function intramolecular transferase activity, phosphotransferases Catalysis of the transfer of a phosphate group from one position to another within a single molecule (more detail) 11 NA Homo sapiens

GOA TAX013645 GO:0001222 molecular function transcription corepressor binding Interacting selectively and non-covalently with a transcription corepressor, any protein involved in (more detail) 11 NA Homo sapiens

GOA TAX001135 Genes annotated by the GO term GO:0019213. Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. (more detail) 11 NA Homo sapiens

MSigDB PEX000515 PWWP: PWWP domain The PWWP domain is named after a conserved Pro-Trp-Trp-Pro motif 1. The domain binds to Histone-4 me (more detail) 11 NA Homo sapiens

Pfam PEX002663 PARP: Poly(ADP ribose) polymerase catalytic domain Poly(ADP-ribose) polymerase catalyses the covalent attachment of ADP-ribose units from NAD+ to itsel (more detail) 11 NA Homo sapiens

Pfam MOX015669 Genes associated with Computational Drug Signature Tyrphostin AG 1478 Genes associated with Computational Drug Signature Tyrphostin AG 1478, curated by the Drug Signature (more detail) 11 25990557 Homo sapiens

DSigDB WIG000356 IL 4 signaling pathway Interleukin 4 (IL-4) is a cytokine that can lead to development of Th2 cells. The 140 kD IL-4 Recept (more detail) 11 NA Homo sapiens

MSigDB TAX000285 Genes annotated by the GO term GO:0032623. The appearance of interleukin 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. (more detail) 11 NA Homo sapiens

MSigDB MOX001701 Genes associated with Computational Drug Signature butein Genes associated with Computational Drug Signature butein, curated by the Drug Signature Database (D (more detail) 11 25990557 Homo sapiens

DSigDB MOX003569 Genes associated with Computational Drug Signature Isocarbophos Genes associated with Computational Drug Signature Isocarbophos, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens

DSigDB MOX004632 Genes associated with Computational Drug Signature RUTHENIUM Genes associated with Computational Drug Signature RUTHENIUM, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens

DSigDB MOX003951 Genes associated with Computational Drug Signature Diatrizoic acid Genes associated with Computational Drug Signature Diatrizoic acid, curated by the Drug Signature Da (more detail) 11 25990557 Homo sapiens

DSigDB MOX013697 Genes associated with Computational Drug Signature METOPRINE Genes associated with Computational Drug Signature METOPRINE, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens

DSigDB WAG001311 Common Pathway (more detail) 11 NA Homo sapiens

Reactome MAX002741 Pre mitotic cell cycle regulators (CDC) identified in an shRNA screen of the ubiquitin pathway components. The spindle checkpoint prevents chromosome mis-segregation by delaying sister chromatid separation u (more detail) 11 NA Homo sapiens

MSigDB TAX000496 Genes annotated by the GO term GO:0051054. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA. (more detail) 11 NA Homo sapiens

MSigDB MOX000524 Genes associated with Computational Drug Signature ALUMINUM CHLORIDE Genes associated with Computational Drug Signature ALUMINUM CHLORIDE, curated by the Drug Signature (more detail) 11 25990557 Homo sapiens

DSigDB MOX012824 Genes associated with Computational Drug Signature Gefitinib Genes associated with Computational Drug Signature Gefitinib, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens

DSigDB WIG000411 Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle Sonic Hedgehog (Shh) is a secreted protein identified genetically as an important developmental fact (more detail) 11 NA Homo sapiens

MSigDB MEX000894 Genes associated with Approved Drug tiotixene Genes associated with Approved Drug tiotixene, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MOX000313 Genes associated with Computational Drug Signature Cortisol succinate Genes associated with Computational Drug Signature Cortisol succinate, curated by the Drug Signature (more detail) 11 25990557 Homo sapiens

DSigDB WIG000428 Granzyme A mediated Apoptosis Pathway One mechanism used by cytotoxic T cells to kill tumor cells and virus-infected cells is the release (more detail) 11 NA Homo sapiens

MSigDB WIG000368 Reversal of Insulin Resistance by Leptin The insulin resistance of type II diabetes appears to be caused in part by the presence of high leve (more detail) 11 NA Homo sapiens

MSigDB WIG000732 Genes involved in Calnexin/calreticulin cycle (more detail) 11 NA Homo sapiens

MSigDB MOX000124 Genes associated with Computational Drug Signature Alantolactone Genes associated with Computational Drug Signature Alantolactone, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens

DSigDB MOX001019 Genes associated with Computational Drug Signature Triciribine Genes associated with Computational Drug Signature Triciribine, curated by the Drug Signature Databa (more detail) 11 25990557 Homo sapiens

DSigDB MOX004749 Genes associated with Computational Drug Signature thiopental Genes associated with Computational Drug Signature thiopental, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens

DSigDB TAX013830 GO:0001779 biological process natural killer cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a natural (more detail) 11 NA Homo sapiens

GOA TAX015893 GO:0005736 cellular component RNA polymerase I complex RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a mu (more detail) 11 NA Homo sapiens

GOA MOX015490 Genes associated with Computational Drug Signature testosterone Genes associated with Computational Drug Signature testosterone, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens

DSigDB WIG001025 Genes involved in NF kB is activated and signals survival (more detail) 11 NA Homo sapiens

MSigDB MEX000832 Genes associated with Approved Drug mometasone furoate Genes associated with Approved Drug mometasone furoate, curated by the Drug Signature Database (DSig (more detail) 11 25990557 Homo sapiens

DSigDB MOX001221 Genes associated with Computational Drug Signature Cadmium telluride Genes associated with Computational Drug Signature Cadmium telluride, curated by the Drug Signature (more detail) 11 25990557 Homo sapiens

DSigDB MOX003005 Genes associated with Computational Drug Signature Perifosine Genes associated with Computational Drug Signature Perifosine, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens

DSigDB MOX005581 Genes associated with Computational Drug Signature 2,4 PYRIDINEDICARBOXYLIC ACID Genes associated with Computational Drug Signature 2,4-PYRIDINEDICARBOXYLIC ACID, curated by the Dru (more detail) 11 25990557 Homo sapiens

DSigDB MOX004896 Genes associated with Computational Drug Signature aclarubicin Genes associated with Computational Drug Signature aclarubicin, curated by the Drug Signature Databa (more detail) 11 25990557 Homo sapiens

DSigDB MOX015148 Genes associated with Computational Drug Signature Sorafenib Genes associated with Computational Drug Signature Sorafenib, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens

DSigDB WAG000213 regulation of transcriptional activity by pml The PML nuclear bodies are ring-shaped nuclear substructures associated with the regulation of trans (more detail) 11 NA Homo sapiens

BioCarta FEX003432 Viral Llovet06 12genes Table 1. Genes Significantly Dysregulated in Early HCC Compared With Dysplatic Nodules; 5 genes were (more detail) 11 17087938 Homo sapiens

GeneSigDB WAG001024 trka receptor signaling pathway Nerve growth factor (NGF) is a neurotrophic factor that stimulates neurol survival and growth throug (more detail) 11 NA Homo sapiens

BioCarta WAG001017 hemoglobins chaperone The function of hemoglobin in oxygen transport by red blood cells requires precise assembly of a tet (more detail) 11 NA Homo sapiens

BioCarta GEX000537 cytogenetic studies cytogenetic studies associated genes. PAGER constructed this gene set by grouping all genes which ar (more detail) 11 NA Homo sapiens

GAD MOX015826 Genes associated with Computational Drug Signature Vatalanib succinate Genes associated with Computational Drug Signature Vatalanib succinate, curated by the Drug Signatur (more detail) 11 25990557 Homo sapiens

DSigDB MAX000845 Genes from the lightyellow module which are up regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1 palmitoyl 2 arachidonyl sn 3 glycerophosphorylcholine (oxPAPC). Oxidized phospholipids are thought to promote atherogenesis by stimulating endothelial cells (ECs) t (more detail) 11 NA Homo sapiens

MSigDB MEX000512 Genes associated with Approved Drug beclomethasone Genes associated with Approved Drug beclomethasone, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens

DSigDB MOX004059 Genes associated with Computational Drug Signature estramustine Genes associated with Computational Drug Signature estramustine, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens

DSigDB MOX005003 Genes associated with Computational Drug Signature quinolinic acid Genes associated with Computational Drug Signature quinolinic acid, curated by the Drug Signature Da (more detail) 11 25990557 Homo sapiens

DSigDB MOX017415 Genes associated with Computational Drug Signature nitrous oxide Genes associated with Computational Drug Signature nitrous oxide, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens

DSigDB MOX012697 Genes associated with Computational Drug Signature flavin adenine dinucleotide Genes associated with Computational Drug Signature flavin adenine dinucleotide, curated by the Drug (more detail) 11 25990557 Homo sapiens

DSigDB FEX011734 hsa miR 518b HITS-CLIP, Functional MTI (Weak) (more detail) 11 NA Homo sapiens