Y-U
(more detail)
439 NA Homo sapiens
TAX019814
GO:0019787 molecular function ubiquitin like protein transferase activity Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y (more detail) 463 NA Homo sapiens
TAX021916
GO:0032991 cellular component protein containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipi (more detail) 4915 NA Homo sapiens
TAX016349
GO:0006464 biological process cellular protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polyp (more detail) 2961 NA Homo sapiens
TAX023298
GO:0036211 biological process protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polyp (more detail) 2961 NA Homo sapiens
TAX024354
GO:0043412 biological process macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysacchar (more detail) 3156 NA Homo sapiens
TAX019752
GO:0019538 biological process protein metabolic process The chemical reactions and pathways involving a protein. Includes protein modification. (more detail) 4056 NA Homo sapiens
TAX024653
GO:0044267 biological process cellular protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general (more detail) 3259 NA Homo sapiens
TAX016382
GO:0006511 biological process ubiquitin dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 448 NA Homo sapiens
TAX019889
GO:0019941 biological process modification dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 454 NA Homo sapiens
TAX024488
GO:0043632 biological process modification dependent macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by cova (more detail) 464 NA Homo sapiens
TAX027094
GO:0051603 biological process proteolysis involved in cellular protein catabolic process The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pat (more detail) 526 NA Homo sapiens
TAX031704
GO:0140096 molecular function catalytic activity, acting on a protein Catalytic activity that acts to modify a protein. (more detail) 2386 NA Homo sapiens
TAX021011
GO:0031463 cellular component Cul3 RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form (more detail) 71 NA Homo sapiens
TAX019187
GO:0016740 molecular function transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-co (more detail) 2422 NA Homo sapiens
TAX013304
GO:0000209 biological process protein polyubiquitination Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. (more detail) 237 NA Homo sapiens
TAX024652
GO:0044265 biological process cellular macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecul (more detail) 750 NA Homo sapiens
TAX017939
GO:0010498 biological process proteasomal protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 279 NA Homo sapiens
TAX017473
GO:0009057 biological process macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of h (more detail) 907 NA Homo sapiens
TAX024191
GO:0043161 biological process proteasome mediated ubiquitin dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 257 NA Homo sapiens
TAX020341
GO:0030163 biological process protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of th (more detail) 368 NA Homo sapiens
TAX016380
GO:0006508 biological process proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide (more detail) 1264 NA Homo sapiens
TAX024504
GO:0043687 biological process post translational protein modification The process of covalently altering one or more amino acids in a protein after the protein has been c (more detail) 362 NA Homo sapiens
TAX019572
GO:0019005 cellular component SCF ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form (more detail) 50 NA Homo sapiens
TAX032172
GO:1901575 biological process organic substance catabolic process The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecula (more detail) 1548 NA Homo sapiens
TAX024644
GO:0044248 biological process cellular catabolic process The chemical reactions and pathways resulting in the breakdown of substances, carried out by individ (more detail) 1554 NA Homo sapiens
TAX028518
GO:0061630 molecular function ubiquitin protein ligase activity Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X (more detail) 231 NA Homo sapiens
TAX028530
GO:0061659 molecular function ubiquitin like protein ligase activity Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction (more detail) 236 NA Homo sapiens
TAX017472
GO:0009056 biological process catabolic process The chemical reactions and pathways resulting in the breakdown of substances, including the breakdow (more detail) 1788 NA Homo sapiens
TAX032165
GO:1901565 biological process organonitrogen compound catabolic process The chemical reactions and pathways resulting in the breakdown of organonitrogen compound. (more detail) 719 NA Homo sapiens
WIG000698
Genes involved in Antigen processing: Ubiquitination & Proteasome degradation (more detail) 199 NA Homo sapiens
WIG000638
Ubiquitin mediated proteolysis Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions (more detail) 130 NA Homo sapiens
TAX013279
GO:0000152 cellular component nuclear ubiquitin ligase complex A ubiquitin ligase complex found in the nucleus. (more detail) 40 NA Homo sapiens
WIG000763
Genes involved in Class I MHC mediated antigen processing & presentation (more detail) 237 NA Homo sapiens
WAG000988
Ubiquitin mediated proteolysis Protein ubiquitition plays an important role in eukaryotic cellular processes. It mainly functions a (more detail) 121 NA Homo sapiens
IEI011120
Protein protein interactors of human gene RBX1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBX1 (SwissProt ID=P (more detail) 148 17535438 Homo sapiens
TAX030168
GO:0080008 cellular component Cul4 RING E3 ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the (more detail) 32 NA Homo sapiens
TAX001049
Genes annotated by the GO term GO:0000151. A protein complex that includes a ubiquitin protein ligase (E3) and other proteins that may confer substrate specificity on the complex. (more detail) 25 NA Homo sapiens
TAX001065
Genes annotated by the GO term GO:0016881. Catalysis of the ligation of an acid to an amino acid via a carbon nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. (more detail) 56 NA Homo sapiens
TAX001383
Genes annotated by the GO term GO:0019787. Catalysis of ATP dependent isopeptide bond formation between the carboxy terminal residues of a small conjugating protein such as ubiquitin or a ubiquitin like protein, and a substrate lysine residue. (more detail) 50 NA Homo sapiens
TAX015868
GO:0005680 cellular component anaphase promoting complex A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby tr (more detail) 21 NA Homo sapiens
TAX000093
Genes annotated by the GO term GO:0044257. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. (more detail) 54 NA Homo sapiens
TAX001228
Genes annotated by the GO term GO:0016879. Catalysis of the ligation of two substances via a carbon nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. (more detail) 65 NA Homo sapiens
TAX001387
Genes annotated by the GO term GO:0008639. Catalysis of the covalent attachment of small proteins, such as ubiquitin or ubiquitin like proteins, to lysine residues on a target protein. This function may be performed alone or in conjunction with an E3, ubiquitin like protein ligase. (more detail) 51 NA Homo sapiens
TAX020843
GO:0031146 biological process SCF dependent proteasomal ubiquitin dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 23 NA Homo sapiens
TAX016383
GO:0006513 biological process protein monoubiquitination Addition of a single ubiquitin group to a protein. (more detail) 60 NA Homo sapiens
TAX001445
Genes annotated by the GO term GO:0004842. Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N ubiquityllysine. (more detail) 48 NA Homo sapiens
TAX000542
Genes annotated by the GO term GO:0030163. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. (more detail) 65 NA Homo sapiens
TAX020842
GO:0031145 biological process anaphase promoting complex dependent catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 36 NA Homo sapiens
WAG000074
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (more detail) 16 NA Homo sapiens
TAX029226
GO:0070979 biological process protein K11 linked ubiquitination A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubi (more detail) 28 NA Homo sapiens
TAX019100
GO:0016574 biological process histone ubiquitination The modification of histones by addition of ubiquitin groups. (more detail) 40 NA Homo sapiens
WAG000667
APC/C mediated degradation of cell cycle proteins (more detail) 15 NA Homo sapiens
WAG000906
Inactivation of APC/C via direct inhibition of the APC/C complex (more detail) 18 NA Homo sapiens
IEI004657
Protein protein interactors of human gene FBXO5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO5 (SwissProt ID= (more detail) 32 17535438 Homo sapiens
TAX000570
Genes annotated by the GO term GO:0016567. The process by which one or more ubiquitin moieties are added to a protein. (more detail) 39 NA Homo sapiens
WAG000466
APC/C:Cdc20 mediated degradation of mitotic proteins (more detail) 19 NA Homo sapiens
WIG000929
Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (more detail) 19 NA Homo sapiens
WAG001346
Regulation of APC/C activators between G1/S and early anaphase (more detail) 19 NA Homo sapiens
WAG000455
APC Cdc20 mediated degradation of Nek2A (more detail) 20 NA Homo sapiens
WAG001293
APC/C:Cdc20 mediated degradation of Cyclin B (more detail) 17 NA Homo sapiens
WIG000768
Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (more detail) 17 NA Homo sapiens
WIG000700
Genes involved in APC Cdc20 mediated degradation of Nek2A (more detail) 23 NA Homo sapiens
WAG000509
Phosphorylation of the APC/C (more detail) 16 NA Homo sapiens
WIG000701
Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B (more detail) 21 NA Homo sapiens
TAX030929
GO:0097602 molecular function cullin family protein binding Interacting selectively and non-covalently with any member of the cullin family, hydrophobic protein (more detail) 18 NA Homo sapiens
WIG001074
Genes involved in Phosphorylation of the APC/C (more detail) 18 NA Homo sapiens
IEI002180
Protein protein interactors of human gene CDC26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC26 (SwissProt ID= (more detail) 23 17535438 Homo sapiens
TAX022733
GO:0035102 cellular component PRC1 complex A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-11 (more detail) 12 NA Homo sapiens
TAX021012
GO:0031464 cellular component Cul4A RING E3 ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form (more detail) 12 NA Homo sapiens
TAX013280
GO:0000153 cellular component cytoplasmic ubiquitin ligase complex A ubiquitin ligase complex found in the cytoplasm. (more detail) 12 NA Homo sapiens
TAX022129
GO:0033522 biological process histone H2A ubiquitination The modification of histone H2A by addition of one or more ubiquitin groups. (more detail) 22 NA Homo sapiens
IEI000558
Protein protein interactors of human gene ANAPC16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC16 (SwissProt I (more detail) 18 17535438 Homo sapiens
IEI000557
Protein protein interactors of human gene ANAPC15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC15 (SwissProt I (more detail) 11 17535438 Homo sapiens
TAX021010
GO:0031462 cellular component Cul2 RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form (more detail) 11 NA Homo sapiens
TAX000992
Genes annotated by the GO term GO:0000152. A ubiquitin ligase complex found in the nucleus. (more detail) 10 NA Homo sapiens
IEI000556
Protein protein interactors of human gene ANAPC13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC13 (SwissProt I (more detail) 13 17535438 Homo sapiens
MAX003000
Subunits of the anaphase promoting complex (APC). Genomic instability can be found in most cancer cells. Cell proliferation is under tight control to (more detail) 12 NA Homo sapiens
IEI003377
Protein protein interactors of human gene DCUN1D2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCUN1D2 (SwissProt I (more detail) 13 17535438 Homo sapiens
TAX020953
GO:0031371 cellular component ubiquitin conjugating enzyme complex Any complex that possesses ubiquitin conjugating enzyme activity. (more detail) 9 NA Homo sapiens
TAX021014
GO:0031466 cellular component Cul5 RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form (more detail) 7 NA Homo sapiens
PEX001617
Cullin: Cullin family (more detail) 7 NA Homo sapiens
IEI003378
Protein protein interactors of human gene DCUN1D3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCUN1D3 (SwissProt I (more detail) 12 17535438 Homo sapiens
TAX030640
GO:0097027 molecular function ubiquitin protein transferase activator activity Increases the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent att (more detail) 8 NA Homo sapiens
PEX002503
Kelch 1: Kelch motif The kelch motif was initially discovered in Kelch (Swiss:Q04652). In this protein there are six copi (more detail) 6 NA Homo sapiens
TAX020698
GO:0030891 cellular component VCB complex A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for e (more detail) 6 NA Homo sapiens
IEI011862
Protein protein interactors of human gene SCML1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCML1 (SwissProt ID= (more detail) 8 17535438 Homo sapiens
TAX022124
GO:0033503 cellular component HULC complex A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin (more detail) 5 NA Homo sapiens
TAX029671
GO:0071797 cellular component LUBAC complex A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targe (more detail) 5 NA Homo sapiens
TAX021013
GO:0031465 cellular component Cul4B RING E3 ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form (more detail) 5 NA Homo sapiens
PEX000357
F box like: F box like This is an F-box-like family. (more detail) 5 NA Homo sapiens
TAX021015
GO:0031467 cellular component Cul7 RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form (more detail) 5 NA Homo sapiens
TAX013529
GO:0000835 cellular component ER ubiquitin ligase complex A ubiquitin ligase complex found in the ER. (more detail) 5 NA Homo sapiens
TAX013530
GO:0000836 cellular component Hrd1p ubiquitin ligase complex A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membran (more detail) 5 NA Homo sapiens
TAX017888
GO:0010265 biological process SCF complex assembly The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc (more detail) 6 NA Homo sapiens
TAX027595
GO:0055131 molecular function C3HC4 type RING finger domain binding Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3 (more detail) 6 NA Homo sapiens
PEX000032
BACK: BTB And C terminal Kelch This domain is found associated with Pfam:PF00651 and Pfam:PF01344 1. The BACK domain is found juxta (more detail) 4 NA Homo sapiens
PEX001701
Cullin Nedd8: Cullin protein neddylation domain This is the neddylation site of cullin proteins which are a family of structurally related proteins (more detail) 4 NA Homo sapiens
TAX030647
GO:0097039 biological process protein linear polyubiquitination A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-termina (more detail) 3 NA Homo sapiens
PEX000817
Cullin binding: Cullin binding This domain binds to cullins and to Rbx-1, components of an E3 ubiquitin ligase complex for neddylat (more detail) 3 NA Homo sapiens
IEI003332
Protein protein interactors of human gene DCAF15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCAF15 (SwissProt ID (more detail) 3 17535438 Homo sapiens
TAX029560
GO:0071596 biological process ubiquitin dependent protein catabolic process via the N end rule pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently ta (more detail) 3 NA Homo sapiens
TAX034263
GO:1990452 cellular component Parkin FBXW7 Cul1 ubiquitin ligase complex A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) a (more detail) 3 NA Homo sapiens
PEX002192
IBR: IBR domain, a half RING finger domain The IBR (In Between Ring fingers) domain is often found to occur between pairs of ring fingers (Pfam (more detail) 3 NA Homo sapiens
MEX002466
Genes associated with Perturbagen Signature 2 deoxy D glucose Genes associated with Perturbagen Signature 2-deoxy-D-glucose, curated by the Drug Signature Databas (more detail) 3 25990557 Homo sapiens
TAX013531
GO:0000839 cellular component Hrd1p ubiquitin ligase ERAD L complex A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains dur (more detail) 3 NA Homo sapiens
TAX016777
GO:0007091 biological process metaphase/anaphase transition of mitotic cell cycle The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, trigger (more detail) 4 NA Homo sapiens
IEI012371
Protein protein interactors of human gene SLC25A43 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLC25A43 (SwissProt (more detail) 4 17535438 Homo sapiens
IEI007201
Protein protein interactors of human gene LDHD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LDHD (SwissProt ID=Q (more detail) 4 17535438 Homo sapiens
TAX024845
GO:0044784 biological process metaphase/anaphase transition of cell cycle The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cyc (more detail) 4 NA Homo sapiens
IEI011877
Protein protein interactors of human gene SCNN1D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SCNN1D (SwissProt ID (more detail) 4 17535438 Homo sapiens
PEX001181
ANAPC3: Anaphase promoting complex, cyclosome, subunit 3 Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosom (more detail) 4 NA Homo sapiens
IEI015024
Protein protein interactors of human gene WDR76 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR76 (SwissProt ID= (more detail) 4 17535438 Homo sapiens
PEX000368
ANAPC4 WD40: Anaphase promoting complex subunit 4 WD40 domain Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilise (more detail) 4 NA Homo sapiens
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GOA 
