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Quick fact for:    ASPP1_HUMAN

41 (medium- to high-quality) out of 139 (all quality) protein-protein interactions are found in HAPPI.


Category Reference to External data Sources
Uniprot ID ASPP1_HUMAN  (Click here for interactions)
Uniprot Accession Number Q96KQ4
Full Name Apoptosis-stimulating of p53 protein 1
Gene Symbol PPP1R13B
Function Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.
Sequence Length 1090 AA.
Molecular Weight 119585
Primary References MEDLINE = 21541920
PUBMED =11684014
Database Cross References UniprotID : ASPP1_HUMAN
Ensembl : ENSG00000088808
KEGG : hsa:23368
HPD : HPD_1209 , HPD_1381 , HPD_140 , HPD_1408 , HPD_1424 , HPD_1579 , HPD_179 , HPD_351 , HPD_736 , HPD_745 , HPD_749 , HPD_963 ,
PharmGKB : PA33622
RefSeq : NP_056131.2
IPI : IPI00306903,
UniGene : Hs.436113 ,
GeneCards : PPP1R13B ,
HGNC : HGNC:14950 ,
ProDom : PD000066 ,
GoID : GO:0005737 , GO:0005634 , GO:0005515 , GO:0006917 , GO:0045786 ,
Protein Sequence MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDHMMYEHLQIWG
PRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGDKRTEYGVGNPRVELTLSELQDMAARQQQ
QIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNL
SAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQ
LNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYI
QVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVK
QGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRP
SAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADK
GSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGS
LSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLAN
APRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLE
ELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA
PSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYE
VEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAI
FASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILR
RKDESETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA