Y-SUMO
(more detail)
24 NA Homo sapiens
TAX001256
Genes annotated by the GO term GO:0003774. Catalysis of movement along a polymeric molecule such as a microfilament or microtubule, coupled to the hydrolysis of a nucleoside triphosphate. (more detail) 28 NA Homo sapiens
PEX000566
C2: C2 domain (more detail) 26 NA Homo sapiens
WIG000110
Integrin family cell surface interactions (more detail) 26 NA Homo sapiens
WIG000657
Genes involved in activated TAK1 mediates p38 MAPK activation (more detail) 17 NA Homo sapiens
TAX017592
GO:0009200 biological process deoxyribonucleoside triphosphate metabolic process The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consist (more detail) 17 NA Homo sapiens
TAX019178
GO:0016722 molecular function oxidoreductase activity, oxidizing metal ions Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered. (more detail) 17 NA Homo sapiens
MEX000868
Genes associated with Approved Drug alitretinoin Genes associated with Approved Drug alitretinoin, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
TAX022751
GO:0035173 molecular function histone kinase activity Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-so (more detail) 17 NA Homo sapiens
WIG001082
Genes involved in PKA mediated phosphorylation of CREB (more detail) 17 NA Homo sapiens
TAX014870
GO:0003951 molecular function NAD+ kinase activity Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+). (more detail) 17 NA Homo sapiens
MEX000745
Genes associated with Approved Drug vardenafil Genes associated with Approved Drug vardenafil, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
TAX021019
GO:0031489 molecular function myosin V binding Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule inv (more detail) 17 NA Homo sapiens
TAX018968
GO:0016307 molecular function phosphatidylinositol phosphate kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bis (more detail) 17 NA Homo sapiens
IEI011407
Protein protein interactors of human gene RNF166 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF166 (SwissProt ID (more detail) 17 17535438 Homo sapiens
TAX024341
GO:0043395 molecular function heparan sulfate proteoglycan binding Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan con (more detail) 14 NA Homo sapiens
MEX002415
Genes associated with Kinase Inhibitor Ceritinib Genes associated with Kinase Inhibitor Ceritinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002094
Genes associated with Kinase Inhibitor Tasocitinib Genes associated with Kinase Inhibitor Tasocitinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002123
Genes associated with Kinase Inhibitor Fostamatinib Genes associated with Kinase Inhibitor Fostamatinib, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens
TAX017515
GO:0009113 biological process purine nucleobase biosynthetic process The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two (more detail) 14 NA Homo sapiens
MEX001945
Genes associated with Kinase Inhibitor Kinome 239 Genes associated with Kinase Inhibitor Kinome_239, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002269
Genes associated with Kinase Inhibitor 841290 80 0 Genes associated with Kinase Inhibitor 841290-80-0, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002361
Genes associated with Kinase Inhibitor CHEMBL495696 Genes associated with Kinase Inhibitor CHEMBL495696, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens
MEX001709
Genes associated with Kinase Inhibitor Kinome 1216 Genes associated with Kinase Inhibitor Kinome_1216, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX001731
Genes associated with Kinase Inhibitor TCMDC 141371 Genes associated with Kinase Inhibitor TCMDC-141371, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens
MEX002082
Genes associated with Kinase Inhibitor GW795493X Genes associated with Kinase Inhibitor GW795493X, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MOX010842
Genes associated with Computational Drug Signature CHEMBL475540 Genes associated with Computational Drug Signature CHEMBL475540, curated by the Drug Signature Datab (more detail) 14 25990557 Homo sapiens
TAX020565
GO:0030553 molecular function cGMP binding Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyc (more detail) 14 NA Homo sapiens
MEX000096
Genes associated with Approved Drug dichlorphenamide Genes associated with Approved Drug dichlorphenamide, curated by the Drug Signature Database (DSigDB (more detail) 14 25990557 Homo sapiens
MEX001318
Genes associated with Kinase Inhibitor Ibrutinib Genes associated with Kinase Inhibitor Ibrutinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
TAX015745
GO:0005388 molecular function calcium transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to th (more detail) 14 NA Homo sapiens
MEX002411
Genes associated with Kinase Inhibitor Imatinib Genes associated with Kinase Inhibitor Imatinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
FOX000435
Genes in the cancer module 106 (more detail) 14 NA Homo sapiens
TAX026437
GO:0050321 molecular function tau protein kinase activity Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein. (more detail) 14 NA Homo sapiens
MEX001718
Genes associated with Kinase Inhibitor Kinome 450 Genes associated with Kinase Inhibitor Kinome_450, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
TAX021563
GO:0032454 molecular function histone demethylase activity (H3 K9 specific) Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = s (more detail) 14 NA Homo sapiens
MEX001428
Genes associated with Kinase Inhibitor Imatinib Genes associated with Kinase Inhibitor Imatinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
TAX019632
GO:0019206 molecular function nucleoside kinase activity Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate. (more detail) 14 NA Homo sapiens
TAX017153
GO:0008252 molecular function nucleotidase activity Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate. (more detail) 14 NA Homo sapiens
MEX001207
Genes associated with Kinase Inhibitor Kinome 439 Genes associated with Kinase Inhibitor Kinome_439, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002135
Genes associated with Kinase Inhibitor Bisindolylmaleimide XI, HCl Genes associated with Kinase Inhibitor Bisindolylmaleimide XI, HCl, curated by the Drug Signature Da (more detail) 14 25990557 Homo sapiens
MEX002412
Genes associated with Kinase Inhibitor Tofacitinib Genes associated with Kinase Inhibitor Tofacitinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002228
Genes associated with Kinase Inhibitor Kinome 3196 Genes associated with Kinase Inhibitor Kinome_3196, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
TAX025821
GO:0046940 biological process nucleoside monophosphate phosphorylation The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a (more detail) 14 NA Homo sapiens
TAX017871
GO:0010181 molecular function FMN binding Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) (more detail) 14 NA Homo sapiens
MEX002375
Genes associated with Kinase Inhibitor dorsomorphin Genes associated with Kinase Inhibitor dorsomorphin, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens
MEX001964
Genes associated with Kinase Inhibitor Kinome 859 Genes associated with Kinase Inhibitor Kinome_859, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
TAX019115
GO:0016594 molecular function glycine binding Interacting selectively and non-covalently with glycine, aminoethanoic acid. (more detail) 14 NA Homo sapiens
MEX002419
Genes associated with Kinase Inhibitor Ibrutinib Genes associated with Kinase Inhibitor Ibrutinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002015
Genes associated with Kinase Inhibitor BS 181 Genes associated with Kinase Inhibitor BS-181, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002283
Genes associated with Kinase Inhibitor Kinome 708 Genes associated with Kinase Inhibitor Kinome_708, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
TAX015333
GO:0004707 molecular function MAP kinase activity Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphoryla (more detail) 14 NA Homo sapiens
PEX001173
zf C3HC4 3: Zinc finger, C3HC4 type (RING finger) (more detail) 14 NA Homo sapiens
MOX003921
Genes associated with Computational Drug Signature p,p' DDD Genes associated with Computational Drug Signature p,p'-DDD, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens
TAX016185
GO:0006206 biological process pyrimidine nucleobase metabolic process The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogeno (more detail) 19 NA Homo sapiens
TAX029359
GO:0071276 biological process cellular response to cadmium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 31 NA Homo sapiens
TAX032406
GO:1902186 biological process regulation of viral release from host cell Any process that modulates the frequency, rate or extent of viral release from host cell. (more detail) 31 NA Homo sapiens
MOX004106
Genes associated with Computational Drug Signature floxuridine Genes associated with Computational Drug Signature floxuridine, curated by the Drug Signature Databa (more detail) 31 25990557 Homo sapiens
MEX000006
Genes associated with Approved Drug dopamine Genes associated with Approved Drug dopamine, curated by the Drug Signature Database (DSigDB). (more detail) 31 25990557 Homo sapiens
MEX000765
Genes associated with Approved Drug methotrexate Genes associated with Approved Drug methotrexate, curated by the Drug Signature Database (DSigDB). (more detail) 31 25990557 Homo sapiens
MOX004409
Genes associated with Computational Drug Signature nicardipine Genes associated with Computational Drug Signature nicardipine, curated by the Drug Signature Databa (more detail) 31 25990557 Homo sapiens
IEI011386
Protein protein interactors of human gene RNF125 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF125 (SwissProt ID (more detail) 21 17535438 Homo sapiens
IEI003206
Protein protein interactors of human gene CYB5A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CYB5A (SwissProt ID= (more detail) 21 17535438 Homo sapiens
MOX000235
Genes associated with Computational Drug Signature CHLOROTHALONIL Genes associated with Computational Drug Signature CHLOROTHALONIL, curated by the Drug Signature Dat (more detail) 21 25990557 Homo sapiens
WIG000164
S1P1 pathway (more detail) 21 NA Homo sapiens
MEX000017
Genes associated with Approved Drug acetaminophen Genes associated with Approved Drug acetaminophen, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens
TAX016174
GO:0006182 biological process cGMP biosynthetic process The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosph (more detail) 21 NA Homo sapiens
TAX023849
GO:0042454 biological process ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside i (more detail) 21 NA Homo sapiens
TAX030300
GO:0090050 biological process positive regulation of cell migration involved in sprouting angiogenesis Any process that increases the frequency, rate or extent of cell migration involved in sprouting ang (more detail) 21 NA Homo sapiens
MOX013135
Genes associated with Computational Drug Signature INDIRUBIN 3' MONOXIME Genes associated with Computational Drug Signature INDIRUBIN-3'-MONOXIME, curated by the Drug Signat (more detail) 29 25990557 Homo sapiens
WIG000791
Genes involved in Degradation of the extracellular matrix (more detail) 29 NA Homo sapiens
WIG001933
One Carbon Metabolism One Carbon Metabolism (more detail) 29 NA Homo sapiens
WIG000155
Reelin signaling pathway (more detail) 29 NA Homo sapiens
MOX012024
Genes associated with Computational Drug Signature clozapine Genes associated with Computational Drug Signature clozapine, curated by the Drug Signature Database (more detail) 29 25990557 Homo sapiens
WIG000070
Glypican 1 network (more detail) 27 NA Homo sapiens
WAG000446
Reelin signaling pathway (more detail) 27 NA Homo sapiens
WIG001098
Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC (more detail) 27 NA Homo sapiens
TAX001202
Genes annotated by the GO term GO:0016836. Catalysis of the cleavage of a carbon oxygen bond by elimination of water. (more detail) 27 NA Homo sapiens
WIG001119
Genes involved in Pyrimidine metabolism (more detail) 23 NA Homo sapiens
WIG001262
Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex (more detail) 23 NA Homo sapiens
WIG000568
Nitrogen metabolism (more detail) 23 NA Homo sapiens
TAX029421
GO:0071377 biological process cellular response to glucagon stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 25 NA Homo sapiens
TAX017584
GO:0009190 biological process cyclic nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide (more detail) 25 NA Homo sapiens
WIG001113
Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation (more detail) 25 NA Homo sapiens
TAX024002
GO:0042759 biological process long chain fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty (more detail) 25 NA Homo sapiens
TAX027419
GO:0052652 biological process cyclic purine nucleotide metabolic process The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phospha (more detail) 25 NA Homo sapiens
WIG001412
Statin Pathway, Pharmacodynamics Genes involved in mediating statin effects on hepatic cholesterol metabolism and consequent effects (more detail) 25 NA Homo sapiens
MOX001830
Genes associated with Computational Drug Signature Prochloraz Genes associated with Computational Drug Signature Prochloraz, curated by the Drug Signature Databas (more detail) 25 25990557 Homo sapiens
MEX000353
Genes associated with Approved Drug mitomycin c Genes associated with Approved Drug mitomycin c, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
TAX014902
GO:0003995 molecular function acyl CoA dehydrogenase activity Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. (more detail) 16 NA Homo sapiens
TAX015313
GO:0004675 molecular function transmembrane receptor protein serine/threonine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to in (more detail) 16 NA Homo sapiens
WIG000954
Genes involved in JNK (c Jun kinases) phosphorylation and activation mediated by activated human TAK1 (more detail) 16 NA Homo sapiens
TAX030179
GO:0080111 biological process DNA demethylation The removal of a methyl group from one or more nucleotides within an DNA molecule. (more detail) 16 NA Homo sapiens
MOX006892
Genes associated with Computational Drug Signature ALDOSTERONE Genes associated with Computational Drug Signature ALDOSTERONE, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens
TAX015326
GO:0004697 molecular function protein kinase C activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylgl (more detail) 16 NA Homo sapiens
MEX000018
Genes associated with Approved Drug acetazolamide Genes associated with Approved Drug acetazolamide, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
TAX001196
Genes annotated by the GO term GO:0016814. Catalysis of the hydrolysis of any non peptide carbon nitrogen bond in a cyclic amidine, a compound of the form R C(=NH) NH2. (more detail) 16 NA Homo sapiens
TAX024154
GO:0043101 biological process purine containing compound salvage Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or n (more detail) 16 NA Homo sapiens
MOX015097
Genes associated with Computational Drug Signature simvastatin Genes associated with Computational Drug Signature simvastatin, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens
MEX000802
Genes associated with Approved Drug lapatinib Genes associated with Approved Drug lapatinib, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
FOX000431
Genes in the cancer module 102 (more detail) 18 NA Homo sapiens
MOX012577
Genes associated with Computational Drug Signature estradiol Genes associated with Computational Drug Signature estradiol, curated by the Drug Signature Database (more detail) 18 25990557 Homo sapiens
MOX004764
Genes associated with Computational Drug Signature ticlopidine Genes associated with Computational Drug Signature ticlopidine, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens
TAX001206
Genes annotated by the GO term GO:0004428. Catalysis of the phosphorylation of myo inositol (1,2,3,5/4,6 cyclohexanehexol) or a phosphatidylinositol. (more detail) 18 NA Homo sapiens
MEX000414
Genes associated with Approved Drug cytarabine Genes associated with Approved Drug cytarabine, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
MOX015857
Genes associated with Computational Drug Signature vinblastine Genes associated with Computational Drug Signature vinblastine, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens
MOX001335
Genes associated with Computational Drug Signature tryptamine Genes associated with Computational Drug Signature tryptamine, curated by the Drug Signature Databas (more detail) 18 25990557 Homo sapiens
WIG000455
uCalpain and friends in Cell spread The mammalian calpain gene family curently contains 13 distinct large subunit products most of which (more detail) 18 NA Homo sapiens
IEI014239
Protein protein interactors of human gene TRIM35 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM35 (SwissProt ID (more detail) 18 17535438 Homo sapiens
MEX002003
Genes associated with Kinase Inhibitor Kinome 474 Genes associated with Kinase Inhibitor Kinome_474, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MEX001472
Genes associated with Kinase Inhibitor PI 103 Genes associated with Kinase Inhibitor PI-103, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MEX001488
Genes associated with Kinase Inhibitor GSK2213727A Genes associated with Kinase Inhibitor GSK2213727A, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
WIG000680
Genes involved in Adenylate cyclase inhibitory pathway (more detail) 13 NA Homo sapiens
MEX000308
Genes associated with Approved Drug sulfanilamide Genes associated with Approved Drug sulfanilamide, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MEX002141
Genes associated with Kinase Inhibitor roscovitine Genes associated with Kinase Inhibitor roscovitine, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MOX015215
Genes associated with Computational Drug Signature SU11652 Genes associated with Computational Drug Signature SU11652, curated by the Drug Signature Database ( (more detail) 13 25990557 Homo sapiens
MEX001844
Genes associated with Kinase Inhibitor CHEMBL1999931 Genes associated with Kinase Inhibitor CHEMBL1999931, curated by the Drug Signature Database (DSigDB (more detail) 13 25990557 Homo sapiens
MOX007591
Genes associated with Computational Drug Signature CGS 27023A Genes associated with Computational Drug Signature CGS-27023A, curated by the Drug Signature Databas (more detail) 13 25990557 Homo sapiens
PEX000151
PDEase I: 3'5' cyclic nucleotide phosphodiesterase (more detail) 13 NA Homo sapiens
MEX002319
Genes associated with Kinase Inhibitor Kinome 491 Genes associated with Kinase Inhibitor Kinome_491, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
TAX023225
GO:0036041 molecular function long chain fatty acid binding Interacting selectively and non-covalently with a long-chain fatty acid. A long-chain fatty acid is (more detail) 13 NA Homo sapiens
TAX015959
GO:0005832 cellular component chaperonin containing T complex A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor. (more detail) 13 NA Homo sapiens
WAG000544
Xenobiotics (more detail) 13 NA Homo sapiens
MEX001688
Genes associated with Kinase Inhibitor GW575808A Genes associated with Kinase Inhibitor GW575808A, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
TAX022771
GO:0035240 molecular function dopamine binding Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by (more detail) 13 NA Homo sapiens
TAX020970
GO:0031402 molecular function sodium ion binding Interacting selectively and non-covalently with sodium ions (Na+). (more detail) 13 NA Homo sapiens
TAX001059
Genes annotated by the GO term GO:0004114. Catalysis of the reaction: nucleoside 3',5' cyclic phosphate + H2O = nucleoside 5' phosphate. (more detail) 13 NA Homo sapiens
MEX001397
Genes associated with Kinase Inhibitor AGN PC 04WTVX Genes associated with Kinase Inhibitor AGN-PC-04WTVX, curated by the Drug Signature Database (DSigDB (more detail) 13 25990557 Homo sapiens
MEX002041
Genes associated with Kinase Inhibitor Kinome 506 Genes associated with Kinase Inhibitor Kinome_506, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MEX001504
Genes associated with Kinase Inhibitor PKCbeta Inhibitor Genes associated with Kinase Inhibitor PKCbeta Inhibitor, curated by the Drug Signature Database (DS (more detail) 13 25990557 Homo sapiens
PEX000638
Cadherin: Cadherin domain (more detail) 13 NA Homo sapiens
WAG000886
Endogenous sterols (more detail) 13 NA Homo sapiens
TAX017154
GO:0008253 molecular function 5' nucleotidase activity Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. (more detail) 13 NA Homo sapiens
TAX001103
Genes annotated by the GO term GO:0004089. Catalysis of the reaction: H2CO3 = CO2 + H2O. (more detail) 13 NA Homo sapiens
WIG001117
Genes involved in Purine salvage (more detail) 13 NA Homo sapiens
MEX000731
Genes associated with Approved Drug nicotine Genes associated with Approved Drug nicotine, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
PEX001420
Pkinase C: Protein kinase C terminal domain (more detail) 13 NA Homo sapiens
MEX002215
Genes associated with Kinase Inhibitor resveratrol Genes associated with Kinase Inhibitor resveratrol, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
TAX028909
GO:0070402 molecular function NADPH binding Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine din (more detail) 13 NA Homo sapiens
IEI009743
Protein protein interactors of human gene PELI1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PELI1 (SwissProt ID= (more detail) 28 17535438 Homo sapiens
IEI009673
Protein protein interactors of human gene PDE6D from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDE6D (SwissProt ID= (more detail) 28 17535438 Homo sapiens
TAX016386
GO:0006517 biological process protein deglycosylation The removal of sugar residues from a glycosylated protein. (more detail) 28 NA Homo sapiens
MOX003633
Genes associated with Computational Drug Signature 58 64 0 Genes associated with Computational Drug Signature 58-64-0, curated by the Drug Signature Database ( (more detail) 28 25990557 Homo sapiens
TAX025470
GO:0046134 biological process pyrimidine nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of one of a family of organic molecul (more detail) 28 NA Homo sapiens
WIG000965
Genes involved in Lipoprotein metabolism (more detail) 28 NA Homo sapiens
IEI014615
Protein protein interactors of human gene UBOX5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBOX5 (SwissProt ID= (more detail) 20 17535438 Homo sapiens
TAX023652
GO:0042069 biological process regulation of catecholamine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 20 NA Homo sapiens
TAX016617
GO:0006825 biological process copper ion transport The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means (more detail) 20 NA Homo sapiens
TAX023645
GO:0042053 biological process regulation of dopamine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 20 NA Homo sapiens
GEX000631
endometrial cancer endometrial cancer associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 20 NA Homo sapiens
IEI003821
Protein protein interactors of human gene DTX3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DTX3 (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens
WAG001020
erk and pi 3 kinase are necessary for collagen binding in corneal epithelia Activation of the MAPK kise pathway has been identified as a mechanism that integrins use to regulat (more detail) 26 NA Homo sapiens
MOX002269
Genes associated with Computational Drug Signature Tyrphostin 23 Genes associated with Computational Drug Signature Tyrphostin 23, curated by the Drug Signature Data (more detail) 26 25990557 Homo sapiens
WIG000098
IL8 and CXCR1 mediated signaling events (more detail) 26 NA Homo sapiens
MOX015667
Genes associated with Computational Drug Signature Tyrphostin 23 Genes associated with Computational Drug Signature Tyrphostin 23, curated by the Drug Signature Data (more detail) 26 25990557 Homo sapiens
MAX000648
The lung adenocarcinoma TSP (tumor sequencing project) genes that were found significantly mutated by at least one method. Determining the genetic basis of cancer requires comprehensive analyses of large collections of hist (more detail) 26 NA Homo sapiens
WIG000136
p38 MAPK signaling pathway (more detail) 26 NA Homo sapiens
WIG001185
Genes involved in Sema4D induced cell migration and growth cone collapse (more detail) 26 NA Homo sapiens
MEX000558
Genes associated with Approved Drug dobutamine Genes associated with Approved Drug dobutamine, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens
TAX022451
GO:0034377 biological process plasma lipoprotein particle assembly The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein par (more detail) 26 NA Homo sapiens
MOX001260
Genes associated with Computational Drug Signature 1 NAPHTHOL Genes associated with Computational Drug Signature 1-NAPHTHOL, curated by the Drug Signature Databas (more detail) 26 25990557 Homo sapiens
TAX017481
GO:0009065 biological process glutamine family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine famil (more detail) 26 NA Homo sapiens
WIG001938
Signal Transduction of S1P Receptor Signal Transduction of S1P Receptor (more detail) 24 NA Homo sapiens
TAX023835
GO:0042430 biological process indole containing compound metabolic process The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) sk (more detail) 24 NA Homo sapiens
TAX020168
GO:0022400 biological process regulation of rhodopsin mediated signaling pathway Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling. (more detail) 24 NA Homo sapiens
WIG000958
Genes involved in Kinesins (more detail) 24 NA Homo sapiens
WIG000165
S1P2 pathway (more detail) 24 NA Homo sapiens
MOX013503
Genes associated with Computational Drug Signature lovastatin Genes associated with Computational Drug Signature lovastatin, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens
MOX003346
Genes associated with Computational Drug Signature Tozasertib Genes associated with Computational Drug Signature Tozasertib, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens
WIG001399
Acetaminophen Pathway, Pharmacokinetics Stylized diagram showing acetaminophen metabolism and transport in the liver and kidney. (more detail) 24 NA Homo sapiens
IEI009462
Protein protein interactors of human gene PAK6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PAK6 (SwissProt ID=Q (more detail) 22 17535438 Homo sapiens
IEI011408
Protein protein interactors of human gene RNF167 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF167 (SwissProt ID (more detail) 22 17535438 Homo sapiens
WIG001027
Genes involved in Nitric oxide stimulates guanylate cyclase (more detail) 22 NA Homo sapiens
MOX011939
Genes associated with Computational Drug Signature cholecalciferol Genes associated with Computational Drug Signature cholecalciferol, curated by the Drug Signature Da (more detail) 22 25990557 Homo sapiens
WIG000432
Aspirin Blocks Signaling Pathway Involved in Platelet Activation Activation of the protease-activated GPCRs in platelets contributes to platelet activation in clotti (more detail) 22 NA Homo sapiens
TAX001122
Genes annotated by the GO term GO:0048037. Interacting selectively with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. (more detail) 22 NA Homo sapiens
TAX022907
GO:0035510 biological process DNA dealkylation The removal of an alkyl group from one or more nucleotides within an DNA molecule. (more detail) 22 NA Homo sapiens
MOX015586
Genes associated with Computational Drug Signature Tozasertib Genes associated with Computational Drug Signature Tozasertib, curated by the Drug Signature Databas (more detail) 22 25990557 Homo sapiens
GEX000362
cardiovascular disease cardiovascular disease associated genes. PAGER constructed this gene set by grouping all genes which (more detail) 22 NA Homo sapiens
TAX025471
GO:0046135 biological process pyrimidine nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecul (more detail) 22 NA Homo sapiens
WIG000392
Nitric Oxide Signaling Pathway Glutamatergic-mediated nitric oxide (NO) production occurs via the N-methyl-D-aspartic acid (NMDA) p (more detail) 22 NA Homo sapiens
TAX019278
GO:0016881 molecular function acid amino acid ligase activity Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomita (more detail) 22 NA Homo sapiens
MEX000955
Genes associated with Approved Drug isotretinoin Genes associated with Approved Drug isotretinoin, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens
WIG000114
LPA4 mediated signaling events (more detail) 15 NA Homo sapiens
WIG001407
Etoposide Pathway, Pharmacokinetics/Pharmacodynamics Etoposide cellular disposition and effects. (more detail) 15 NA Homo sapiens
FEX001389
Leukemia Chiaretti05 16genes Table 4. Kinase genes with high-level gene expression in samples without known molecular rearrangeme (more detail) 15 16243790 Homo sapiens
WAG000848
tgf beta signaling pathway TGF-beta regulates growth and proliferation of cells, blocking growth of many cell types. The TGF-be (more detail) 15 NA Homo sapiens
MOX012062
Genes associated with Computational Drug Signature coumarin Genes associated with Computational Drug Signature coumarin, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens
MEX000095
Genes associated with Approved Drug diclofenac Genes associated with Approved Drug diclofenac, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
WAG000396
Alkaloid biosynthesis I (more detail) 15 NA Homo sapiens
TAX015201
GO:0004523 molecular function RNA DNA hybrid ribonuclease activity Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters. (more detail) 15 NA Homo sapiens
MOX000383
Genes associated with Computational Drug Signature Paraoxon methyl Genes associated with Computational Drug Signature Paraoxon-methyl, curated by the Drug Signature Da (more detail) 15 25990557 Homo sapiens
TAX022014
GO:0033169 biological process histone H3 K9 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the his (more detail) 15 NA Homo sapiens
WIG000821
Genes involved in Endogenous sterols (more detail) 15 NA Homo sapiens
TAX022131
GO:0033539 biological process fatty acid beta oxidation using acyl CoA dehydrogenase A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which convert (more detail) 15 NA Homo sapiens
IEI000425
Protein protein interactors of human gene AKAP13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AKAP13 (SwissProt ID (more detail) 27 17535438 Homo sapiens
MOX014254
Genes associated with Computational Drug Signature omeprazole Genes associated with Computational Drug Signature omeprazole, curated by the Drug Signature Databas (more detail) 27 25990557 Homo sapiens
TAX000062
Genes annotated by the GO term GO:0006816. The directed movement of calcium (Ca) ions into, out of, within or between cells. (more detail) 27 NA Homo sapiens
MOX004512
Genes associated with Computational Drug Signature phenylbutazone Genes associated with Computational Drug Signature phenylbutazone, curated by the Drug Signature Dat (more detail) 27 25990557 Homo sapiens
MOX007515
Genes associated with Computational Drug Signature catechol Genes associated with Computational Drug Signature catechol, curated by the Drug Signature Database (more detail) 27 25990557 Homo sapiens
WIG000773
Genes involved in CREB phosphorylation through the activation of Ras (more detail) 27 NA Homo sapiens
WIG001226
Genes involved in Signalling to RAS (more detail) 27 NA Homo sapiens
FEX000008
Bladder Ying Hao02 30genes Table 1. List of differentially expressed genes in TCC samples (more detail) 27 12644218 Homo sapiens
FEX000284
Breast Bieche04 27genes Table 2. Target genes tested; 27 xenobiotic-metabolizing target genes the ESR1/ERalpha gene (coding (more detail) 27 15084249 Homo sapiens
MOX001458
Genes associated with Computational Drug Signature 60282 87 3 Genes associated with Computational Drug Signature 60282-87-3, curated by the Drug Signature Databas (more detail) 27 25990557 Homo sapiens
TAX023155
GO:0035924 biological process cellular response to vascular endothelial growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 27 NA Homo sapiens
IEI010346
Protein protein interactors of human gene PPP1R14A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R14A (SwissProt (more detail) 17 17535438 Homo sapiens
TAX016392
GO:0006525 biological process arginine metabolic process The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. (more detail) 17 NA Homo sapiens
MOX004036
Genes associated with Computational Drug Signature EDTA Genes associated with Computational Drug Signature EDTA, curated by the Drug Signature Database (DSi (more detail) 17 25990557 Homo sapiens
MEX000872
Genes associated with Approved Drug melphalan Genes associated with Approved Drug melphalan, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
MOX014380
Genes associated with Computational Drug Signature PD 173074 Genes associated with Computational Drug Signature PD 173074, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens
WAG000448
Class I PI3K signaling events (more detail) 17 NA Homo sapiens
MOX001945
Genes associated with Computational Drug Signature AT 877 Genes associated with Computational Drug Signature AT 877, curated by the Drug Signature Database (D (more detail) 17 25990557 Homo sapiens
TAX022450
GO:0034375 biological process high density lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein partic (more detail) 17 NA Homo sapiens
MOX001042
Genes associated with Computational Drug Signature Solvent Yellow ?14 Genes associated with Computational Drug Signature Solvent Yellow-?14, curated by the Drug Signature (more detail) 17 25990557 Homo sapiens
MOX007396
Genes associated with Computational Drug Signature bromocriptine Genes associated with Computational Drug Signature bromocriptine, curated by the Drug Signature Data (more detail) 17 25990557 Homo sapiens
MEX000211
Genes associated with Approved Drug methazolamide Genes associated with Approved Drug methazolamide, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
WIG000291
Regulation of ck1/cdk5 by type 1 glutamate receptors Cdk5 is a cyclin dependent protein kinase involved in dopaminergic signaling in the neostriatal regi (more detail) 17 NA Homo sapiens
WAG000661
p38 MAPK signaling pathway (more detail) 17 NA Homo sapiens
MOX002364
Genes associated with Computational Drug Signature o6 benzylguanine Genes associated with Computational Drug Signature o6-benzylguanine, curated by the Drug Signature D (more detail) 17 25990557 Homo sapiens
WIG001344
Bisphosphonate Pathway, Pharmacodynamics Representation of genes involved in bisphosphonates' effects in osteoclasts. (more detail) 17 NA Homo sapiens
WIG001670
Shigella Invasion Shigella Invasion (more detail) 25 NA Homo sapiens
MOX005142
Genes associated with Computational Drug Signature Permethrin Genes associated with Computational Drug Signature Permethrin, curated by the Drug Signature Databas (more detail) 25 25990557 Homo sapiens
MOX014719
Genes associated with Computational Drug Signature QUINACRINE DIHYDROCHLORIDE Genes associated with Computational Drug Signature QUINACRINE DIHYDROCHLORIDE, curated by the Drug S (more detail) 25 25990557 Homo sapiens
TAX013310
GO:0000217 molecular function DNA secondary structure binding Interacting selectively and non-covalently with DNA containing secondary structure elements such as (more detail) 25 NA Homo sapiens
MEX001816
Genes associated with Kinase Inhibitor Kinome 490 Genes associated with Kinase Inhibitor Kinome_490, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MOX012907
Genes associated with Computational Drug Signature Go 6976 Genes associated with Computational Drug Signature Go 6976, curated by the Drug Signature Database ( (more detail) 12 25990557 Homo sapiens
TAX001244
Genes annotated by the GO term GO:0008235. Catalysis of the hydrolysis of terminal peptide linkages in oligopeptides or polypeptides. Enzymes of this class contain a chelated metal ion essential to their catalytic activity at their active sites. (more detail) 12 NA Homo sapiens
MEX000703
Genes associated with Approved Drug brinzolamide Genes associated with Approved Drug brinzolamide, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001510
Genes associated with Kinase Inhibitor go 6983 Genes associated with Kinase Inhibitor go 6983, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MOX001809
Genes associated with Computational Drug Signature Cerebrosterol Genes associated with Computational Drug Signature Cerebrosterol, curated by the Drug Signature Data (more detail) 12 25990557 Homo sapiens
MOX004782
Genes associated with Computational Drug Signature tranylcypromine Genes associated with Computational Drug Signature tranylcypromine, curated by the Drug Signature Da (more detail) 12 25990557 Homo sapiens
TAX019910
GO:0019992 molecular function diacylglycerol binding Interacting selectively and non-covalently with diacylglycerol, a diester of glycerol and two fatty (more detail) 12 NA Homo sapiens
TAX032186
GO:1901611 molecular function phosphatidylglycerol binding Interacting selectively and non-covalently with phosphatidylglycerol. (more detail) 12 NA Homo sapiens
PEX002346
Arf: ADP ribosylation factor family Pfam combines a number of different Prosite families together (more detail) 12 NA Homo sapiens
TAX001240
Genes annotated by the GO term GO:0004707. Catalysis of the phosphorylation of proteins. Mitogen activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation or differentiation inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli. (more detail) 12 NA Homo sapiens
TAX001308
Genes annotated by the GO term GO:0005548. Enables the directed movement of phospholipids into, out of, within or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono or diester. (more detail) 12 NA Homo sapiens
MEX001806
Genes associated with Kinase Inhibitor Vandetanib Genes associated with Kinase Inhibitor Vandetanib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
WIG000415
Rab GTPases Mark Targets In The Endocytotic Machinery The eukaryotic cell contains compartments with distinct functions bounded by lipid bilayer membranes (more detail) 12 NA Homo sapiens
MEX001423
Genes associated with Kinase Inhibitor Kinome 249 Genes associated with Kinase Inhibitor Kinome_249, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX002408
Genes associated with Kinase Inhibitor Afatinib Genes associated with Kinase Inhibitor Afatinib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
TAX020705
GO:0030898 molecular function actin dependent ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of an ac (more detail) 12 NA Homo sapiens
MEX001634
Genes associated with Kinase Inhibitor Tandutinib Genes associated with Kinase Inhibitor Tandutinib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001209
Genes associated with Kinase Inhibitor 172889 26 8 Genes associated with Kinase Inhibitor 172889-26-8, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MOX003985
Genes associated with Computational Drug Signature dihydroergotamine Genes associated with Computational Drug Signature dihydroergotamine, curated by the Drug Signature (more detail) 12 25990557 Homo sapiens
TAX023988
GO:0042738 biological process exogenous drug catabolic process The chemical reactions and pathways resulting in the breakdown of a drug that has originated externa (more detail) 12 NA Homo sapiens
MEX001323
Genes associated with Kinase Inhibitor Tyrphostin AG 1478 Genes associated with Kinase Inhibitor Tyrphostin AG 1478, curated by the Drug Signature Database (D (more detail) 12 25990557 Homo sapiens
MEX001329
Genes associated with Kinase Inhibitor Afatinib Genes associated with Kinase Inhibitor Afatinib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
TAX017541
GO:0009143 biological process nucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compo (more detail) 12 NA Homo sapiens
TAX031968
GO:1900750 molecular function oligopeptide binding Interacting selectively and non-covalently with an oligopeptide. (more detail) 12 NA Homo sapiens
PEX002465
C1 1: Phorbol esters/diacylglycerol binding domain (C1 domain) This domain is also known as the Protein kinase C conserved region 1 (C1) domain. (more detail) 12 NA Homo sapiens
MEX001933
Genes associated with Kinase Inhibitor rottlerin Genes associated with Kinase Inhibitor rottlerin, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001944
Genes associated with Kinase Inhibitor GSK1173862A Genes associated with Kinase Inhibitor GSK1173862A, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX002294
Genes associated with Kinase Inhibitor PYRAZOLOPYRIDAZINE 1 Genes associated with Kinase Inhibitor PYRAZOLOPYRIDAZINE 1, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens
MEX002002
Genes associated with Kinase Inhibitor Aurora Kinase/Cdk Inhibitor Genes associated with Kinase Inhibitor Aurora Kinase/Cdk Inhibitor, curated by the Drug Signature Da (more detail) 12 25990557 Homo sapiens
MEX001913
Genes associated with Kinase Inhibitor Purvalanol B Genes associated with Kinase Inhibitor Purvalanol B, curated by the Drug Signature Database (DSigDB) (more detail) 12 25990557 Homo sapiens
MEX001610
Genes associated with Kinase Inhibitor CHEMBL1965660 Genes associated with Kinase Inhibitor CHEMBL1965660, curated by the Drug Signature Database (DSigDB (more detail) 12 25990557 Homo sapiens
MEX002340
Genes associated with Kinase Inhibitor Kinome 10 Genes associated with Kinase Inhibitor Kinome_10, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001775
Genes associated with Kinase Inhibitor Kinome 3513 Genes associated with Kinase Inhibitor Kinome_3513, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
TAX015797
GO:0005542 molecular function folic acid binding Interacting selectively and non-covalently with folic acid, pteroylglutamic acid. Folic acid is wide (more detail) 12 NA Homo sapiens
MEX001427
Genes associated with Kinase Inhibitor GSK1326255A Genes associated with Kinase Inhibitor GSK1326255A, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX000972
Genes associated with Approved Drug dorzolamide Genes associated with Approved Drug dorzolamide, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX002367
Genes associated with Kinase Inhibitor Kinome 501 Genes associated with Kinase Inhibitor Kinome_501, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
PEX000411
AAA: ATPase family associated with various cellular activities (AAA) AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, o (more detail) 12 NA Homo sapiens
PEX000754
Peptidase M10: Matrixin The members of this family are enzymes that cleave peptides. These proteases require zinc for cataly (more detail) 12 NA Homo sapiens
MOX014858
Genes associated with Computational Drug Signature Ro 4396686 Genes associated with Computational Drug Signature Ro-4396686, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens
FEX001162
Immune Kong10 12genes ImmPort TGF betaFamilyMemberReceptors ImmPort genelist of cytokine receptors: TGF-beta Family Member Receptors (more detail) 12 20460173 Homo sapiens
WIG001099
Genes involved in Presynaptic nicotinic acetylcholine receptors (more detail) 12 NA Homo sapiens
WIG001162
Genes involved in Reversible Hydration of Carbon Dioxide (more detail) 12 NA Homo sapiens
MEX001644
Genes associated with Kinase Inhibitor 172889 27 9 Genes associated with Kinase Inhibitor 172889-27-9, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001931
Genes associated with Kinase Inhibitor GW305178X Genes associated with Kinase Inhibitor GW305178X, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
TAX029235
GO:0070989 biological process oxidative demethylation The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. ele (more detail) 12 NA Homo sapiens
TAX029069
GO:0070679 molecular function inositol 1,4,5 trisphosphate binding Interacting selectively and non-covalently with inositol 1,4,5 trisphosphate. (more detail) 12 NA Homo sapiens
MEX000603
Genes associated with Approved Drug simvastatin Genes associated with Approved Drug simvastatin, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens
WIG002023
Tamoxifen metabolism Tamoxifen metabolism (more detail) 19 NA Homo sapiens
TAX015544
GO:0005003 molecular function ephrin receptor activity Combining with an ephrin to initiate a change in cell activity. (more detail) 19 NA Homo sapiens
TAX017546
GO:0009148 biological process pyrimidine nucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate (more detail) 19 NA Homo sapiens
MOX001383
Genes associated with Computational Drug Signature 4 Aminodiphenylamine Genes associated with Computational Drug Signature 4-Aminodiphenylamine, curated by the Drug Signatu (more detail) 19 25990557 Homo sapiens
WIG000468
alpha Linolenic acid metabolism (more detail) 19 NA Homo sapiens
MEX000368
Genes associated with Approved Drug spironolactone Genes associated with Approved Drug spironolactone, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens
MOX001793
Genes associated with Computational Drug Signature FLAVONE Genes associated with Computational Drug Signature FLAVONE, curated by the Drug Signature Database ( (more detail) 23 25990557 Homo sapiens
MOX004969
Genes associated with Computational Drug Signature pravastatin Genes associated with Computational Drug Signature pravastatin, curated by the Drug Signature Databa (more detail) 23 25990557 Homo sapiens
TAX000680
Genes annotated by the GO term GO:0051056. Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction. (more detail) 23 NA Homo sapiens
MOX015240
Genes associated with Computational Drug Signature Sulfuretin Genes associated with Computational Drug Signature Sulfuretin, curated by the Drug Signature Databas (more detail) 23 25990557 Homo sapiens
WIG000346
Multiple antiapoptotic pathways from IGF 1R signaling lead to BAD phosphorylation IGF-1R, the type 1 receptor for insulin-like growth factor, mediates cell survival and growth in res (more detail) 23 NA Homo sapiens
MOX017189
Genes associated with Computational Drug Signature Ketanserin Genes associated with Computational Drug Signature Ketanserin, curated by the Drug Signature Databas (more detail) 23 25990557 Homo sapiens
TAX018190
GO:0010882 biological process regulation of cardiac muscle contraction by calcium ion signaling Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing t (more detail) 23 NA Homo sapiens
MEX000635
Genes associated with Approved Drug aripiprazole Genes associated with Approved Drug aripiprazole, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens
TAX017483
GO:0009067 biological process aspartate family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the aspartate famil (more detail) 23 NA Homo sapiens
TAX020642
GO:0030742 molecular function GTP dependent protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or (more detail) 23 NA Homo sapiens
TAX018640
GO:0015645 molecular function fatty acid ligase activity Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP. (more detail) 21 NA Homo sapiens
MOX000907
Genes associated with Computational Drug Signature POTASSIUM BROMATE Genes associated with Computational Drug Signature POTASSIUM BROMATE, curated by the Drug Signature (more detail) 21 25990557 Homo sapiens
WAG000607
gamma Hexachlorocyclohexane degradation (more detail) 21 NA Homo sapiens
TAX018182
GO:0010874 biological process regulation of cholesterol efflux Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux i (more detail) 21 NA Homo sapiens
MOX015416
Genes associated with Computational Drug Signature tamoxifen Genes associated with Computational Drug Signature tamoxifen, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens
WIG001284
Genes involved in TRAF6 mediated NF kB activation (more detail) 21 NA Homo sapiens
MOX007549
Genes associated with Computational Drug Signature Cdk9 Inhibitor II Genes associated with Computational Drug Signature Cdk9 Inhibitor II, curated by the Drug Signature (more detail) 21 25990557 Homo sapiens
IEI005481
Protein protein interactors of human gene GRB14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRB14 (SwissProt ID= (more detail) 21 17535438 Homo sapiens
WEX000027
ERBB2 Signaling The genes related to erbb2 signaling (signaling pathways) in tumor using next-generation sequencer ( (more detail) 21 NA Homo sapiens
TAX017605
GO:0009214 biological process cyclic nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide (more detail) 14 NA Homo sapiens
MEX002204
Genes associated with Kinase Inhibitor curcumin Genes associated with Kinase Inhibitor curcumin, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
TAX001127
Genes annotated by the GO term GO:0004112. Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate. (more detail) 14 NA Homo sapiens
FOX000643
Genes in the cancer module 328 (more detail) 14 NA Homo sapiens
WIG001402
Abacavir Pathway, Pharmacokinetics/Pharmacodynamics Schematic representation of abacavir metabolism and mechanism of action. The potential mechanism of (more detail) 14 NA Homo sapiens
TAX015726
GO:0005344 molecular function oxygen carrier activity Enables the directed movement of oxygen into, out of or within a cell, or between cells. (more detail) 14 NA Homo sapiens
MOX007338
Genes associated with Computational Drug Signature BMS 536924 Genes associated with Computational Drug Signature BMS-536924, curated by the Drug Signature Databas (more detail) 14 25990557 Homo sapiens
MEX002083
Genes associated with Kinase Inhibitor Go 6976 Genes associated with Kinase Inhibitor Go 6976, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
WAG001623
alpha Linolenic acid metabolism (more detail) 14 NA Homo sapiens
IEI011498
Protein protein interactors of human gene RPH3AL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPH3AL (SwissProt ID (more detail) 14 17535438 Homo sapiens
IEI012134
Protein protein interactors of human gene SH2B2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH2B2 (SwissProt ID= (more detail) 24 17535438 Homo sapiens
TAX017609
GO:0009218 biological process pyrimidine ribonucleotide metabolic process The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of (more detail) 24 NA Homo sapiens
MEX000557
Genes associated with Approved Drug etoposide Genes associated with Approved Drug etoposide, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens
MOX004865
Genes associated with Computational Drug Signature 2 Acetamidofluorene Genes associated with Computational Drug Signature 2-Acetamidofluorene, curated by the Drug Signatur (more detail) 24 25990557 Homo sapiens
MOX004432
Genes associated with Computational Drug Signature norethindrone Genes associated with Computational Drug Signature norethindrone, curated by the Drug Signature Data (more detail) 24 25990557 Homo sapiens
WIG000115
VEGFR3 signaling in lymphatic endothelium (more detail) 24 NA Homo sapiens
IEI001755
Protein protein interactors of human gene CAMKMT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CAMKMT (SwissProt ID (more detail) 16 17535438 Homo sapiens
IEI011497
Protein protein interactors of human gene RPH3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPH3A (SwissProt ID= (more detail) 16 17535438 Homo sapiens
TAX020215
GO:0022848 molecular function acetylcholine gated cation selective channel activity Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acet (more detail) 16 NA Homo sapiens
WIG000429
Sonic Hedgehog (Shh) Pathway Sonic Hedgehog (Shh) is one of a family of three secreted proteins, including Indian Hedgehog (Ihh) (more detail) 16 NA Homo sapiens
MOX001246
Genes associated with Computational Drug Signature 2 Propenoicacid, 3 phenyl Genes associated with Computational Drug Signature 2-Propenoicacid, 3-phenyl-, curated by the Drug S (more detail) 16 25990557 Homo sapiens
TAX017600
GO:0009208 biological process pyrimidine ribonucleoside triphosphate metabolic process The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound con (more detail) 16 NA Homo sapiens
PEX001876
ADH zinc N: Zinc binding dehydrogenase (more detail) 16 NA Homo sapiens
TAX016000
GO:0005892 cellular component acetylcholine gated channel complex A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions m (more detail) 16 NA Homo sapiens
WIG001087
Genes involved in Platelet calcium homeostasis (more detail) 16 NA Homo sapiens
PEX002317
EGF: EGF like domain There is no clear separation between noise and signal. Pfam:PF00053 is very similar, but has 8 inste (more detail) 16 NA Homo sapiens
WIG001374
Carbamazepine Pathway, Pharmacokinetics Stylized liver cell depicting candidate genes involved in the pharmacokinetics of carbamazepine. (more detail) 16 NA Homo sapiens
MEX000266
Genes associated with Approved Drug phenylbutazone Genes associated with Approved Drug phenylbutazone, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
WAG001613
Caffeine metabolism (more detail) 16 NA Homo sapiens
MOX002190
Genes associated with Computational Drug Signature Isoorientin Genes associated with Computational Drug Signature Isoorientin, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens
MOX003479
Genes associated with Computational Drug Signature 1,1 Bis(4 hydroxyphenyl)cyclohexane Genes associated with Computational Drug Signature 1,1-Bis(4-hydroxyphenyl)cyclohexane, curated by t (more detail) 16 25990557 Homo sapiens
WIG001195
Genes involved in Signaling by BMP (more detail) 22 NA Homo sapiens
TAX017611
GO:0009220 biological process pyrimidine ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a com (more detail) 22 NA Homo sapiens
PEX000769
SET: SET domain SET domains are protein lysine methyltransferase enzymes. SET domains appear to be protein-protein i (more detail) 22 NA Homo sapiens
MEX000341
Genes associated with Approved Drug troglitazone Genes associated with Approved Drug troglitazone, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens
WAG001236
links between pyk2 and map kinases This diagram is a compilation of Pyk2 effort cascades. In specific cell types the receptor and effo (more detail) 22 NA Homo sapiens
TAX021909
GO:0032982 cellular component myosin filament A protein complex containing myosin heavy chains, plus associated light chains and other proteins, i (more detail) 22 NA Homo sapiens
MOX012918
Genes associated with Computational Drug Signature GR 127935 Genes associated with Computational Drug Signature GR-127935, curated by the Drug Signature Database (more detail) 22 25990557 Homo sapiens
TAX022129
GO:0033522 biological process histone H2A ubiquitination The modification of histone H2A by addition of one or more ubiquitin groups. (more detail) 22 NA Homo sapiens
IEI007743
Protein protein interactors of human gene MATK from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MATK (SwissProt ID=P (more detail) 22 17535438 Homo sapiens
IEI012162
Protein protein interactors of human gene SH3RF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH3RF1 (SwissProt ID (more detail) 22 17535438 Homo sapiens
IEI009956
Protein protein interactors of human gene PIP5K1A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PIP5K1A (SwissProt I (more detail) 22 17535438 Homo sapiens
MOX007067
Genes associated with Computational Drug Signature Aripiprazole Genes associated with Computational Drug Signature Aripiprazole, curated by the Drug Signature Datab (more detail) 18 25990557 Homo sapiens
TAX029618
GO:0071682 cellular component endocytic vesicle lumen The volume enclosed by the membrane of an endocytic vesicle. (more detail) 18 NA Homo sapiens
WIG001331
Tamoxifen Pathway, Pharmacokinetics Tamoxifen metabolism in the liver. (more detail) 18 NA Homo sapiens
FOX000613
Genes in the cancer module 294 (more detail) 18 NA Homo sapiens
MOX000334
Genes associated with Computational Drug Signature ERIODICTYOL Genes associated with Computational Drug Signature ERIODICTYOL, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens
WIG001243
Genes involved in Synthesis and interconversion of nucleotide di and triphosphates (more detail) 18 NA Homo sapiens
WIG000649
Genes involved in ABCA transporters in lipid homeostasis (more detail) 18 NA Homo sapiens
TAX015215
GO:0004550 molecular function nucleoside diphosphate kinase activity Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. (more detail) 18 NA Homo sapiens
TAX023286
GO:0036150 biological process phosphatidylserine acyl chain remodeling Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation re (more detail) 20 NA Homo sapiens
WIG001743
Mismatch Repair Pathway in Eukaryotes Mismatch Repair Pathway in Eukaryotes (more detail) 20 NA Homo sapiens
MOX004700
Genes associated with Computational Drug Signature sulfinpyrazone Genes associated with Computational Drug Signature sulfinpyrazone, curated by the Drug Signature Dat (more detail) 20 25990557 Homo sapiens
TAX001089
Genes annotated by the GO term GO:0015662. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high energy aspartyl phosphoryl enzyme intermediate. (more detail) 20 NA Homo sapiens
WAG001222
Glyoxylate and dicarboxylate metabolism (more detail) 20 NA Homo sapiens
WIG000242
Wnt/Ca2+/cyclic GMP signaling. na (more detail) 20 NA Homo sapiens
TAX016370
GO:0006491 biological process N glycan processing The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosacc (more detail) 20 NA Homo sapiens
TAX029370
GO:0071294 biological process cellular response to zinc ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 20 NA Homo sapiens
IEI009429
Protein protein interactors of human gene PACRG from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PACRG (SwissProt ID= (more detail) 20 17535438 Homo sapiens
TAX024202
GO:0043176 molecular function amine binding Interacting selectively and non-covalently with any organic compound that is weakly basic in charact (more detail) 11 NA Homo sapiens
TAX024281
GO:0043295 molecular function glutathione binding Interacting selectively and non-covalently with glutathione; a tripeptide composed of the three amin (more detail) 11 NA Homo sapiens
IEI011334
Protein protein interactors of human gene RIPK4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RIPK4 (SwissProt ID= (more detail) 11 17535438 Homo sapiens
MEX001687
Genes associated with Kinase Inhibitor Saracatinib Genes associated with Kinase Inhibitor Saracatinib, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX001836
Genes associated with Kinase Inhibitor CHEMBL456252 Genes associated with Kinase Inhibitor CHEMBL456252, curated by the Drug Signature Database (DSigDB) (more detail) 11 25990557 Homo sapiens
TAX001071
Genes annotated by the GO term GO:0043531. Interacting selectively with ADP, adenosine 5' diphosphate. (more detail) 11 NA Homo sapiens
WIG001356
Imatinib Pathway, Pharmacokinetics/Pharmacodynamics Imatinib Pathway, Pharmacokinetics/Pharmacodynamics (more detail) 11 NA Homo sapiens
MEX001639
Genes associated with Kinase Inhibitor Ruboxistaurin Genes associated with Kinase Inhibitor Ruboxistaurin, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens
TAX015008
GO:0004143 molecular function diacylglycerol kinase activity Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate. (more detail) 11 NA Homo sapiens
TAX001265
Genes annotated by the GO term GO:0004889. (more detail) 11 NA Homo sapiens
MEX001817
Genes associated with Kinase Inhibitor alsterpaullone Genes associated with Kinase Inhibitor alsterpaullone, curated by the Drug Signature Database (DSigD (more detail) 11 25990557 Homo sapiens
MEX001203
Genes associated with Kinase Inhibitor Cdk2 Inhibitor IV, NU6140 Genes associated with Kinase Inhibitor Cdk2 Inhibitor IV, NU6140, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens
TAX001098
Genes annotated by the GO term GO:0015085. Catalysis of the transfer of calcium (Ca) ions from one side of a membrane to the other. (more detail) 11 NA Homo sapiens
TAX000975
Genes annotated by the GO term GO:0005892. A protein complex that acts as an acetylcholine receptor, and forms a transmembrane channel through which ions may pass in response to ligand binding. The complex is a homo or heteropentamer of subunits that are members of a neurotransmitter receptor superfamily. (more detail) 11 NA Homo sapiens
MOX014978
Genes associated with Computational Drug Signature Saracatinib Genes associated with Computational Drug Signature Saracatinib, curated by the Drug Signature Databa (more detail) 11 25990557 Homo sapiens
MEX001244
Genes associated with Kinase Inhibitor 761437 28 9 Genes associated with Kinase Inhibitor 761437-28-9, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX002233
Genes associated with Kinase Inhibitor CHEMBL1969102 Genes associated with Kinase Inhibitor CHEMBL1969102, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens
MEX002305
Genes associated with Kinase Inhibitor Kinome 248 Genes associated with Kinase Inhibitor Kinome_248, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX001820
Genes associated with Kinase Inhibitor CHEMBL1970317 Genes associated with Kinase Inhibitor CHEMBL1970317, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens
MEX001269
Genes associated with Kinase Inhibitor A 443654 Genes associated with Kinase Inhibitor A-443654, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
TAX026973
GO:0051378 molecular function serotonin binding Interacting selectively and non-covalently with serotonin (5-hydroxytryptamine), a monoamine neurotr (more detail) 11 NA Homo sapiens
TAX001091
Genes annotated by the GO term GO:0004003. Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of the DNA helix. (more detail) 11 NA Homo sapiens
TAX001266
Genes annotated by the GO term GO:0004715. Catalysis of the reaction: ATP + a protein L tyrosine = ADP + a protein L tyrosine phosphate. (more detail) 11 NA Homo sapiens
MEX001625
Genes associated with Kinase Inhibitor PDK1/Akt/Flt Dual Pathway Inhibitor Genes associated with Kinase Inhibitor PDK1/Akt/Flt Dual Pathway Inhibitor, curated by the Drug Sign (more detail) 11 25990557 Homo sapiens
MOX003439
Genes associated with Computational Drug Signature trans 1,2 Dihydro 1,2 naphthalenediol Genes associated with Computational Drug Signature trans-1,2-Dihydro-1,2-naphthalenediol, curated by (more detail) 11 25990557 Homo sapiens
TAX017216
GO:0008349 molecular function MAP kinase kinase kinase kinase activity Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kin (more detail) 11 NA Homo sapiens
TAX017549
GO:0009151 biological process purine deoxyribonucleotide metabolic process The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of d (more detail) 11 NA Homo sapiens
MEX000003
Genes associated with Approved Drug bupropion Genes associated with Approved Drug bupropion, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX001348
Genes associated with Kinase Inhibitor GW589933X Genes associated with Kinase Inhibitor GW589933X, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MOX012940
Genes associated with Computational Drug Signature GSK690693 Genes associated with Computational Drug Signature GSK690693, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens
MEX001255
Genes associated with Kinase Inhibitor Kinome 1199 Genes associated with Kinase Inhibitor Kinome_1199, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX002211
Genes associated with Kinase Inhibitor Kinome 812 Genes associated with Kinase Inhibitor Kinome_812, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX001927
Genes associated with Kinase Inhibitor Kinome 528 Genes associated with Kinase Inhibitor Kinome_528, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
TAX014953
GO:0004065 molecular function arylsulfatase activity Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate. (more detail) 11 NA Homo sapiens
WIG000396
Deregulation of CDK5 in Alzheimers Disease Cyclin-dependent kinase 5 (cdk5), a multi-functional kinase, and its neuron-specific activator p35 a (more detail) 11 NA Homo sapiens
TAX001084
Genes annotated by the GO term GO:0004065. Catalysis of the reaction: a phenol sulfate + H2O = a phenol + SO4(2 ) (sulfate). (more detail) 11 NA Homo sapiens
WIG001271
Genes involved in The activation of arylsulfatases (more detail) 11 NA Homo sapiens
MOX012301
Genes associated with Computational Drug Signature Dihydroergotamine mesylate Genes associated with Computational Drug Signature Dihydroergotamine mesylate, curated by the Drug S (more detail) 13 25990557 Homo sapiens
WIG001363
Antimetabolite Pathway Folate Cycle, Pharmacodynamics Model non-tissue specific cancer cell displaying candidate genes which may be involved in the pharma (more detail) 13 NA Homo sapiens
TAX001076
Genes annotated by the GO term GO:0004177. Catalysis of the hydrolysis of N terminal amino acid residues from oligopeptides or polypeptides. (more detail) 13 NA Homo sapiens
TAX001395
Genes annotated by the GO term GO:0003707. Combining with a steroid hormone to initiate a change in cell activity. (more detail) 13 NA Homo sapiens
TAX022454
GO:0034380 biological process high density lipoprotein particle assembly The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprote (more detail) 13 NA Homo sapiens
TAX027710
GO:0060158 biological process phospholipase C activating dopamine receptor signaling pathway The series of molecular signals generated as a consequence of a dopamine receptor binding to its phy (more detail) 13 NA Homo sapiens
MEX000071
Genes associated with Approved Drug chlorthalidone Genes associated with Approved Drug chlorthalidone, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
WIG001054
Genes involved in p38MAPK events (more detail) 13 NA Homo sapiens
TAX021890
GO:0032958 biological process inositol phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6 (more detail) 13 NA Homo sapiens
TAX017640
GO:0009263 biological process deoxyribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound (more detail) 13 NA Homo sapiens
FOX000478
Genes in the cancer module 148 (more detail) 13 NA Homo sapiens
MOX002107
Genes associated with Computational Drug Signature O,P' DDE Genes associated with Computational Drug Signature O,P'-DDE, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens
PEX000778
ADH N: Alcohol dehydrogenase GroES like domain This is the catalytic domain of alcohol dehydrogenases. Many of them contain an inserted zinc bindi (more detail) 13 NA Homo sapiens
MOX001847
Genes associated with Computational Drug Signature Ginkgolide B Genes associated with Computational Drug Signature Ginkgolide B, curated by the Drug Signature Datab (more detail) 13 25990557 Homo sapiens
MOX003926
Genes associated with Computational Drug Signature N,N Diethyl 3 methylbenzamide Genes associated with Computational Drug Signature N,N-Diethyl-3-methylbenzamide, curated by the Dru (more detail) 13 25990557 Homo sapiens
MOX015080
Genes associated with Computational Drug Signature SERTINDOLE Genes associated with Computational Drug Signature SERTINDOLE, curated by the Drug Signature Databas (more detail) 13 25990557 Homo sapiens
TAX029714
GO:0071872 biological process cellular response to epinephrine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 13 NA Homo sapiens
IEI014257
Protein protein interactors of human gene TRIM50 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM50 (SwissProt ID (more detail) 13 17535438 Homo sapiens
WIG000416
Rac 1 cell motility signaling pathway Rac-1 is a small G-protein in the Rho family that regulates cell motility in response to extracellul (more detail) 23 NA Homo sapiens
TAX001287
Genes annotated by the GO term GO:0016627. Catalysis of an oxidation reduction (redox) reaction in which a CH CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. (more detail) 23 NA Homo sapiens
MOX017030
Genes associated with Computational Drug Signature Guanosine 5' monophosphate disodium salt Genes associated with Computational Drug Signature Guanosine 5'-monophosphate disodium salt, curated (more detail) 23 25990557 Homo sapiens
TAX013943
GO:0001935 biological process endothelial cell proliferation The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell popula (more detail) 23 NA Homo sapiens
WIG000398
Hypoxia and p53 in the Cardiovascular system Hypoxic stress, like DNA damage, induces p53 protein accumulation and p53-dependent apoptosis in onc (more detail) 23 NA Homo sapiens
TAX001073
Genes annotated by the GO term GO:0043176. Interacting selectively with any organic compound that is weakly basic in character and contains an amino or a substituted amino group. (more detail) 23 NA Homo sapiens
MEX000170
Genes associated with Approved Drug indomethacin Genes associated with Approved Drug indomethacin, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens
MOX012290
Genes associated with Computational Drug Signature diethylstilbestrol Genes associated with Computational Drug Signature diethylstilbestrol, curated by the Drug Signature (more detail) 23 25990557 Homo sapiens
WAG000831
fmlp induced chemokine gene expression in hmc 1 cells Neutrophils respond to bacterial infection by releasing reactive oxygen species that kill bacteria a (more detail) 23 NA Homo sapiens
MOX004212
Genes associated with Computational Drug Signature ifosfamide Genes associated with Computational Drug Signature ifosfamide, curated by the Drug Signature Databas (more detail) 23 25990557 Homo sapiens
WIG000279
CCR3 signaling in Eosinophils Eosinophils are a key class of leukocytes involved in inflammatory responses, including allergic rea (more detail) 23 NA Homo sapiens
IEI014316
Protein protein interactors of human gene TRPC3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRPC3 (SwissProt ID= (more detail) 23 17535438 Homo sapiens
IEI011415
Protein protein interactors of human gene RNF181 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF181 (SwissProt ID (more detail) 21 17535438 Homo sapiens
TAX035013
GO:2001026 biological process regulation of endothelial cell chemotaxis Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis. (more detail) 21 NA Homo sapiens
MOX016016
Genes associated with Computational Drug Signature hydralazine Genes associated with Computational Drug Signature hydralazine, curated by the Drug Signature Databa (more detail) 21 25990557 Homo sapiens
MOX012587
Genes associated with Computational Drug Signature ethinyl estradiol Genes associated with Computational Drug Signature ethinyl estradiol, curated by the Drug Signature (more detail) 21 25990557 Homo sapiens
TAX025468
GO:0046132 biological process pyrimidine ribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside i (more detail) 21 NA Homo sapiens
TAX019139
GO:0016638 molecular function oxidoreductase activity, acting on the CH NH2 group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or e (more detail) 21 NA Homo sapiens
WAG000632
regulation of ck1/cdk5 by type 1 glutamate receptors Cdk5 is a cyclin dependent protein kise involved in dopaminergic sigling in the neostriatal region o (more detail) 21 NA Homo sapiens
WIG000673
Genes involved in Acyl chain remodelling of PC (more detail) 21 NA Homo sapiens
MOX004245
Genes associated with Computational Drug Signature Ketanserin Genes associated with Computational Drug Signature Ketanserin, curated by the Drug Signature Databas (more detail) 21 25990557 Homo sapiens
MOX003049
Genes associated with Computational Drug Signature Ezetimibe Genes associated with Computational Drug Signature Ezetimibe, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens
MOX000537
Genes associated with Computational Drug Signature propachlor Genes associated with Computational Drug Signature propachlor, curated by the Drug Signature Databas (more detail) 21 25990557 Homo sapiens
TAX025119
GO:0045503 molecular function dynein light chain binding Interacting selectively and non-covalently with a light chain of the dynein complex. (more detail) 21 NA Homo sapiens
TAX015035
GO:0004198 molecular function calcium dependent cysteine type endopeptidase activity Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using (more detail) 21 NA Homo sapiens
MEX000391
Genes associated with Approved Drug apomorphine Genes associated with Approved Drug apomorphine, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens
MOX000169
Genes associated with Computational Drug Signature hypericin Genes associated with Computational Drug Signature hypericin, curated by the Drug Signature Database (more detail) 21 25990557 Homo sapiens
WIG001431
CD27 Pathway CD27 Pathway (more detail) 21 NA Homo sapiens
MOX012826
Genes associated with Computational Drug Signature gemfibrozil Genes associated with Computational Drug Signature gemfibrozil, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens
TAX017601
GO:0009209 biological process pyrimidine ribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosp (more detail) 15 NA Homo sapiens
MOX012423
Genes associated with Computational Drug Signature Doramapimod Genes associated with Computational Drug Signature Doramapimod, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens
TAX024494
GO:0043650 biological process dicarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic ac (more detail) 15 NA Homo sapiens
WIG000394
Nuclear Receptors in Lipid Metabolism and Toxicity Nuclear receptors are transcription factors that are activated upon binding to its ligands. Initiall (more detail) 15 NA Homo sapiens
WIG001225
Genes involved in Signalling to p38 via RIT and RIN (more detail) 15 NA Homo sapiens
FOX000724
Genes in the cancer module 431 (more detail) 15 NA Homo sapiens
TAX018183
GO:0010875 biological process positive regulation of cholesterol efflux Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux i (more detail) 15 NA Homo sapiens
WIG001420
Methotrexate Pathway (Cancer Cell), Pharmacodynamics Methotrexate cellular disposition and effects. (more detail) 15 NA Homo sapiens
TAX023285
GO:0036149 biological process phosphatidylinositol acyl chain remodeling Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation (more detail) 15 NA Homo sapiens
WIG000010
Arf6 downstream pathway (more detail) 15 NA Homo sapiens
MOX013566
Genes associated with Computational Drug Signature Mangostin Genes associated with Computational Drug Signature Mangostin, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens
MOX015656
Genes associated with Computational Drug Signature tryptamine Genes associated with Computational Drug Signature tryptamine, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens
TAX018649
GO:0015671 biological process oxygen transport The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of so (more detail) 15 NA Homo sapiens
WIG000652
Genes involved in Acetylcholine Binding And Downstream Events (more detail) 15 NA Homo sapiens
WIG001924
Fatty Acid Omega Oxidation Fatty Acid Omega Oxidation (more detail) 15 NA Homo sapiens
IEI011248
Protein protein interactors of human gene RGS16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RGS16 (SwissProt ID= (more detail) 15 17535438 Homo sapiens
TAX027222
GO:0051861 molecular function glycolipid binding Interacting selectively and non-covalently with a glycolipid, any compound containing one or more mo (more detail) 19 NA Homo sapiens
MOX002446
Genes associated with Computational Drug Signature Bergamottin Genes associated with Computational Drug Signature Bergamottin, curated by the Drug Signature Databa (more detail) 19 25990557 Homo sapiens
TAX031520
GO:0102568 molecular function phospholipase A2 activity consuming 1,2 dioleoylphosphatidylethanolamine) Catalysis of the reaction: 1-18:1-2-18:1-phosphatidylethanolamine + H2O = 1-oleoyl-sn-glycero-3-phos (more detail) 19 NA Homo sapiens
TAX000919
Genes annotated by the GO term GO:0008305. Any member of a family of heterodimeric transmembrane receptors for cell adhesion molecules. The alpha and beta subunits are noncovalently bonded. (more detail) 19 NA Homo sapiens
TAX031519
GO:0102567 molecular function phospholipase A2 activity (consuming 1,2 dipalmitoylphosphatidylcholine) Catalysis of the reaction: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn- (more detail) 19 NA Homo sapiens
WAG000007
role of mal in rho mediated activation of srf Serum response factor (SRF) is a transcription factor, which binds to a serum response element (SRE) (more detail) 19 NA Homo sapiens
MEX000123
Genes associated with Approved Drug fenofibrate Genes associated with Approved Drug fenofibrate, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens
WAG001471
signaling pathway from g protein families G-aS-coupled receptors stimulate adenylyl cyclase (AC), which synthesizes cAMP from ATP. In contras (more detail) 19 NA Homo sapiens
MOX017355
Genes associated with Computational Drug Signature Phytic acid Genes associated with Computational Drug Signature Phytic acid, curated by the Drug Signature Databa (more detail) 19 25990557 Homo sapiens
TAX030312
GO:0090075 biological process relaxation of muscle A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a numb (more detail) 19 NA Homo sapiens
GEX166739
Cholesterol, total Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (more detail) 19 19060911 Homo sapiens
TAX033385
GO:1904315 molecular function transmitter gated ion channel activity involved in regulation of postsynaptic membrane potential Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane p (more detail) 19 NA Homo sapiens
WIG000371
Role of MAL in Rho Mediated Activation of SRF Serum response factor (SRF) is a transcription factor, which binds to a serum response element (SRE) (more detail) 19 NA Homo sapiens
TAX017959
GO:0010529 biological process negative regulation of transposition Any process that decreases the frequency, rate or extent of transposition. Transposition results in (more detail) 19 NA Homo sapiens
MOX016028
Genes associated with Computational Drug Signature cytidine Genes associated with Computational Drug Signature cytidine, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens
WAG000640
role of erk5 in neuronal survival pathway Axons extend significant distances to innervate target tissues. At the site of innervation, target (more detail) 19 NA Homo sapiens
MOX001301
Genes associated with Computational Drug Signature coumarin Genes associated with Computational Drug Signature coumarin, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens
GEX000421
cholesterol, total cholesterol, total associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 19 NA Homo sapiens
TAX017958
GO:0010528 biological process regulation of transposition Any process that modulates the frequency, rate or extent of transposition. Transposition results in (more detail) 19 NA Homo sapiens
IEI008966
Protein protein interactors of human gene NOXA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NOXA1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens
IEI007898
Protein protein interactors of human gene METAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene METAP2 (SwissProt ID (more detail) 17 17535438 Homo sapiens
IEI004731
Protein protein interactors of human gene FGF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FGF1 (SwissProt ID=P (more detail) 17 17535438 Homo sapiens
TAX024505
GO:0043691 biological process reverse cholesterol transport The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for (more detail) 17 NA Homo sapiens
MOX004849
Genes associated with Computational Drug Signature Yohimbine Genes associated with Computational Drug Signature Yohimbine, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens
MOX013197
Genes associated with Computational Drug Signature Isokaempferide Genes associated with Computational Drug Signature Isokaempferide, curated by the Drug Signature Dat (more detail) 17 25990557 Homo sapiens
TAX013394
GO:0000400 molecular function four way junction DNA binding Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Hol (more detail) 17 NA Homo sapiens
WIG000170
Regulation of cytoplasmic and nuclear SMAD2/3 signaling (more detail) 17 NA Homo sapiens
TAX033408
GO:1904355 biological process positive regulation of telomere capping Any process that activates or increases the frequency, rate or extent of telomere capping. (more detail) 17 NA Homo sapiens
MOX014722
Genes associated with Computational Drug Signature quinalizarin Genes associated with Computational Drug Signature quinalizarin, curated by the Drug Signature Datab (more detail) 17 25990557 Homo sapiens
MOX000172
Genes associated with Computational Drug Signature ferulic acid Genes associated with Computational Drug Signature ferulic acid, curated by the Drug Signature Datab (more detail) 17 25990557 Homo sapiens
WAG001618
Reductive carboxylate cycle (CO2 fixation) (more detail) 17 NA Homo sapiens
MEX001588
Genes associated with Kinase Inhibitor AG F 35231 Genes associated with Kinase Inhibitor AG-F-35231, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX002390
Genes associated with Kinase Inhibitor CHEMBL212299 Genes associated with Kinase Inhibitor CHEMBL212299, curated by the Drug Signature Database (DSigDB) (more detail) 10 25990557 Homo sapiens
MEX002193
Genes associated with Kinase Inhibitor Kinome 1218 Genes associated with Kinase Inhibitor Kinome_1218, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MOX001278
Genes associated with Computational Drug Signature Zearalenol Genes associated with Computational Drug Signature Zearalenol, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens
TAX017823
GO:0009972 biological process cytidine deamination The removal of amino group in the presence of water. (more detail) 10 NA Homo sapiens
MEX001630
Genes associated with Kinase Inhibitor Kinome 2812 Genes associated with Kinase Inhibitor Kinome_2812, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX002168
Genes associated with Kinase Inhibitor GW782612X Genes associated with Kinase Inhibitor GW782612X, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MOX002210
Genes associated with Computational Drug Signature Hypaconitine Genes associated with Computational Drug Signature Hypaconitine, curated by the Drug Signature Datab (more detail) 10 25990557 Homo sapiens
PEX001635
zf B box: B box zinc finger (more detail) 10 NA Homo sapiens
MOX013985
Genes associated with Computational Drug Signature naringenin Genes associated with Computational Drug Signature naringenin, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens
MEX002245
Genes associated with Kinase Inhibitor Kinome 192 Genes associated with Kinase Inhibitor Kinome_192, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX002334
Genes associated with Kinase Inhibitor Nilotinib Genes associated with Kinase Inhibitor Nilotinib, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX001737
Genes associated with Kinase Inhibitor GW612286X Genes associated with Kinase Inhibitor GW612286X, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MOX012803
Genes associated with Computational Drug Signature gamma Imino ATP Genes associated with Computational Drug Signature gamma-Imino-ATP, curated by the Drug Signature Da (more detail) 10 25990557 Homo sapiens
TAX030778
GO:0097267 biological process omega hydroxylase P450 pathway The chemical reactions and pathways by which arachidonic acid is converted to other compounds initia (more detail) 10 NA Homo sapiens
MOX014383
Genes associated with Computational Drug Signature PD 0173956 Genes associated with Computational Drug Signature PD-0173956, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens
MEX001313
Genes associated with Kinase Inhibitor GSK2220400A Genes associated with Kinase Inhibitor GSK2220400A, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX001900
Genes associated with Kinase Inhibitor BMS 345541 free base Genes associated with Kinase Inhibitor BMS-345541 free base, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
MOX003351
Genes associated with Computational Drug Signature 6,7 dihydroxyflavone Genes associated with Computational Drug Signature 6,7-dihydroxyflavone, curated by the Drug Signatu (more detail) 10 25990557 Homo sapiens
TAX027223
GO:0051864 molecular function histone demethylase activity (H3 K36 specific) Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = (more detail) 10 NA Homo sapiens
WIG000679
Genes involved in Adenylate cyclase activating pathway (more detail) 10 NA Homo sapiens
MEX001641
Genes associated with Kinase Inhibitor 1 [4 (4 Aminothieno[2,3 D]pyrimidin 5 Yl)phenyl] 3 [2 Fluoro 5 (Trifluoromethyl)phenyl]urea Genes associated with Kinase Inhibitor 1-[4-(4-Aminothieno[2,3-D]pyrimidin-5-Yl)phenyl]-3-[2-Fluoro- (more detail) 10 25990557 Homo sapiens
MEX001679
Genes associated with Kinase Inhibitor Kinome 504 Genes associated with Kinase Inhibitor Kinome_504, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
TAX028990
GO:0070544 biological process histone H3 K36 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the hi (more detail) 10 NA Homo sapiens
PEX002031
Metallophos: Calcineurin like phosphoesterase This family includes a diverse range of phosphoesterases 1, including protein phosphoserine phosphat (more detail) 10 NA Homo sapiens
MEX001222
Genes associated with Kinase Inhibitor GSK 3 Inhibitor XIII Genes associated with Kinase Inhibitor GSK-3 Inhibitor XIII, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
MEX000658
Genes associated with Approved Drug sildenafil citrate Genes associated with Approved Drug sildenafil citrate, curated by the Drug Signature Database (DSig (more detail) 10 25990557 Homo sapiens
MEX001919
Genes associated with Kinase Inhibitor BMS 345541 free base Genes associated with Kinase Inhibitor BMS-345541 free base, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
MEX001743
Genes associated with Kinase Inhibitor CHEMBL1956068 Genes associated with Kinase Inhibitor CHEMBL1956068, curated by the Drug Signature Database (DSigDB (more detail) 10 25990557 Homo sapiens
MOX008993
Genes associated with Computational Drug Signature CHEMBL230686 Genes associated with Computational Drug Signature CHEMBL230686, curated by the Drug Signature Datab (more detail) 10 25990557 Homo sapiens
WAG000812
1 and 2 Methylnaphthalene degradation (more detail) 10 NA Homo sapiens
MEX001700
Genes associated with Kinase Inhibitor PD 173074 Genes associated with Kinase Inhibitor PD 173074, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX000193
Genes associated with Approved Drug mafenide Genes associated with Approved Drug mafenide, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
TAX022215
GO:0033691 molecular function sialic acid binding Interacting selectively and non-covalently with sialic acid, any of a variety of N- or O- substitute (more detail) 10 NA Homo sapiens
IEI015829
Protein protein interactors of human gene ZNRF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNRF4 (SwissProt ID= (more detail) 10 17535438 Homo sapiens
MEX002075
Genes associated with Kinase Inhibitor 1 [4 (4 aminothieno[2,3 d]pyrimidin 5 yl)phenyl] 3 (3 methylphenyl)urea Genes associated with Kinase Inhibitor 1-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-(3-methylp (more detail) 10 25990557 Homo sapiens
MOX003384
Genes associated with Computational Drug Signature monohydroxymethoxychlor Genes associated with Computational Drug Signature monohydroxymethoxychlor, curated by the Drug Sign (more detail) 10 25990557 Homo sapiens
MOX005477
Genes associated with Computational Drug Signature 10Z Hymenialdisine Genes associated with Computational Drug Signature 10Z-Hymenialdisine, curated by the Drug Signature (more detail) 10 25990557 Homo sapiens
MOX007171
Genes associated with Computational Drug Signature balanol Genes associated with Computational Drug Signature balanol, curated by the Drug Signature Database ( (more detail) 10 25990557 Homo sapiens
TAX016193
GO:0006216 biological process cytidine catabolic process The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a wid (more detail) 10 NA Homo sapiens
TAX017121
GO:0008199 molecular function ferric iron binding Interacting selectively and non-covalently with ferric iron, Fe(III). (more detail) 10 NA Homo sapiens
TAX019116
GO:0016595 molecular function glutamate binding Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid. (more detail) 10 NA Homo sapiens
TAX025440
GO:0046087 biological process cytidine metabolic process The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucl (more detail) 10 NA Homo sapiens
PEX000629
EF hand 1: EF hand The EF-hands can be divided into two classes: signalling proteins and buffering/transport proteins. (more detail) 10 NA Homo sapiens
MOX012431
Genes associated with Computational Drug Signature doxorubicin Genes associated with Computational Drug Signature doxorubicin, curated by the Drug Signature Databa (more detail) 10 25990557 Homo sapiens
MOX014394
Genes associated with Computational Drug Signature PD166326 Genes associated with Computational Drug Signature PD166326, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
IEI015099
Protein protein interactors of human gene XAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XAF1 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens
IEI011406
Protein protein interactors of human gene RNF165 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF165 (SwissProt ID (more detail) 12 17535438 Homo sapiens
MOX005504
Genes associated with Computational Drug Signature 153436 54 5 Genes associated with Computational Drug Signature 153436-54-5, curated by the Drug Signature Databa (more detail) 12 25990557 Homo sapiens
MOX012992
Genes associated with Computational Drug Signature heme Genes associated with Computational Drug Signature heme, curated by the Drug Signature Database (DSi (more detail) 12 25990557 Homo sapiens
TAX018169
GO:0010857 molecular function calcium dependent protein kinase activity Catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the pres (more detail) 12 NA Homo sapiens
FOX000803
Genes in the cancer module 56 (more detail) 12 NA Homo sapiens
WIG001411
Sympathetic Nerve Pathway (Pre and Post Ganglionic Junction) Simplified diagram of a sympathetic neuronal junction displaying genes involved in neurotransmitter (more detail) 12 NA Homo sapiens
TAX017513
GO:0009111 biological process vitamin catabolic process The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unre (more detail) 12 NA Homo sapiens
TAX015811
GO:0005583 cellular component fibrillar collagen trimer Any triple helical collagen trimer that forms fibrils. (more detail) 12 NA Homo sapiens
MOX003474
Genes associated with Computational Drug Signature 4 Cumylphenol Genes associated with Computational Drug Signature 4-Cumylphenol, curated by the Drug Signature Data (more detail) 12 25990557 Homo sapiens
MOX004015
Genes associated with Computational Drug Signature DMPP Genes associated with Computational Drug Signature DMPP, curated by the Drug Signature Database (DSi (more detail) 12 25990557 Homo sapiens
WAG001025
ucalpain and friends in cell spread The mammalian calpain gene family curently contains 13 distinct large subunit products most of which (more detail) 12 NA Homo sapiens
TAX022220
GO:0033700 biological process phospholipid efflux The directed movement of a phospholipid out of a cell or organelle. (more detail) 12 NA Homo sapiens
FEX000735
Breast Culhane09 12genes MolecularSubtype 12 Genes used for breast cancer molecular subtype assignment (more detail) 12 19723662 Homo sapiens
MOX013103
Genes associated with Computational Drug Signature Ilomastat Genes associated with Computational Drug Signature Ilomastat, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens
TAX016435
GO:0006568 biological process tryptophan metabolic process The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol- (more detail) 12 NA Homo sapiens
MEX001992
Genes associated with Kinase Inhibitor bisindolylmaleimide i Genes associated with Kinase Inhibitor bisindolylmaleimide i, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens
TAX015960
GO:0005833 cellular component hemoglobin complex An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated (more detail) 12 NA Homo sapiens
MEX000350
Genes associated with Approved Drug dexamethasone Genes associated with Approved Drug dexamethasone, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
TAX019327
GO:0017000 biological process antibiotic biosynthetic process The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produce (more detail) 12 NA Homo sapiens
WIG000251
Rho Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation The A-kinase anchor protein 13 (AKAP13, also known as AKAP-LBC) is one of a group of structurally di (more detail) 12 NA Homo sapiens
IEI010642
Protein protein interactors of human gene PSMC3IP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMC3IP (SwissProt I (more detail) 20 17535438 Homo sapiens
TAX033170
GO:1903861 biological process positive regulation of dendrite extension Any process that activates or increases the frequency, rate or extent of dendrite extension. (more detail) 20 NA Homo sapiens
IEI011247
Protein protein interactors of human gene RGS14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RGS14 (SwissProt ID= (more detail) 20 17535438 Homo sapiens
WIG001375
Zidovudine Pathway, Pharmacokinetics/Pharmacodynamics Representation of candidate genes involved in the metabolism of zidovudine and its mechanism of anti (more detail) 20 NA Homo sapiens
GEX001252
overall effect overall effect associated genes. PAGER constructed this gene set by grouping all genes which are ass (more detail) 20 NA Homo sapiens
MOX000808
Genes associated with Computational Drug Signature cypermethrin Genes associated with Computational Drug Signature cypermethrin, curated by the Drug Signature Datab (more detail) 20 25990557 Homo sapiens
MOX004209
Genes associated with Computational Drug Signature HYPOCHLOROUS ACID Genes associated with Computational Drug Signature HYPOCHLOROUS ACID, curated by the Drug Signature (more detail) 20 25990557 Homo sapiens
TAX025549
GO:0046386 biological process deoxyribose phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phospho (more detail) 20 NA Homo sapiens
MAX000644
The lung adenocarcinoma TSP (tumor sequencing project) genes mutations in which show positive correlation with the higher overall mutation rate. Determining the genetic basis of cancer requires comprehensive analyses of large collections of hist (more detail) 20 NA Homo sapiens
MOX002843
Genes associated with Computational Drug Signature Ziprasidone Genes associated with Computational Drug Signature Ziprasidone, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens
TAX025694
GO:0046655 biological process folic acid metabolic process The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely (more detail) 18 NA Homo sapiens
WIG000750
Genes involved in cGMP effects (more detail) 18 NA Homo sapiens
WIG000443
Telomeres, Telomerase, Cellular Aging, and Immortality Telomeres, which define the ends of chromosomes, consist of short, tandemly repeated DNA sequences l (more detail) 18 NA Homo sapiens
TAX023284
GO:0036148 biological process phosphatidylglycerol acyl chain remodeling Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation (more detail) 18 NA Homo sapiens
TAX023830
GO:0042423 biological process catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of any of a group of physiologically (more detail) 18 NA Homo sapiens
MOX001389
Genes associated with Computational Drug Signature PHENOTHIAZINE Genes associated with Computational Drug Signature PHENOTHIAZINE, curated by the Drug Signature Data (more detail) 18 25990557 Homo sapiens
TAX017747
GO:0009713 biological process catechol containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Cat (more detail) 18 NA Homo sapiens
WAG001470
transcription factor creb and its extracellular signals The transcription factor CREB binds the cyclic AMP response element (CRE) and activates transcriptio (more detail) 18 NA Homo sapiens
WIG001376
Lamivudine Pathway, Pharmacokinetics/Pharmacodynamics Representation of candidate genes involved in the metabolism of lamivudine and its mechanism of anti (more detail) 18 NA Homo sapiens
TAX018617
GO:0015464 molecular function acetylcholine receptor activity Combining with acetylcholine and transmitting the signal from one side of the membrane to the other (more detail) 18 NA Homo sapiens
WAG001451
hypoxia and p53 in the cardiovascular system Hypoxic stress, like D damage, induces p53 protein accumulation and p53-dependent apoptosis in oncog (more detail) 18 NA Homo sapiens
WAG000628
atm signaling pathway The ataxia telangiectasia-mutated gene (ATM) encodes a protein kise that acts as a tumor suppressor. (more detail) 18 NA Homo sapiens
FOX000663
Genes in the cancer module 354 (more detail) 18 NA Homo sapiens
MOX007049
Genes associated with Computational Drug Signature apomorphine Genes associated with Computational Drug Signature apomorphine, curated by the Drug Signature Databa (more detail) 18 25990557 Homo sapiens
TAX029385
GO:0071318 biological process cellular response to ATP Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 18 NA Homo sapiens
FAX003050
GSEA GO Pancreatic Cancer Tissue Explants (Extracellular Vesicles) Regulation of Actin Cytoskeleton Top 3 pathways enriched in pancreatic cancer tissue extract extracellular vesicle particles compared (more detail) 18 32795414 Homo sapiens
IEI014235
Protein protein interactors of human gene TRIM31 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM31 (SwissProt ID (more detail) 18 17535438 Homo sapiens
IEI011251
Protein protein interactors of human gene RGS19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RGS19 (SwissProt ID= (more detail) 18 17535438 Homo sapiens
WEX000006
Arginine Metabolism The genes related to arginine metabolism (metabolism) in tumor, immune, stroma using next-generation (more detail) 14 NA Homo sapiens
IEI000706
Protein protein interactors of human gene APBA2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APBA2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens
IEI011375
Protein protein interactors of human gene RNF103 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF103 (SwissProt ID (more detail) 14 17535438 Homo sapiens
MOX014837
Genes associated with Computational Drug Signature risperidone Genes associated with Computational Drug Signature risperidone, curated by the Drug Signature Databa (more detail) 14 25990557 Homo sapiens
MOX014487
Genes associated with Computational Drug Signature phenylbutazone Genes associated with Computational Drug Signature phenylbutazone, curated by the Drug Signature Dat (more detail) 14 25990557 Homo sapiens
MOX012560
Genes associated with Computational Drug Signature ERIODICTYOL Genes associated with Computational Drug Signature ERIODICTYOL, curated by the Drug Signature Databa (more detail) 14 25990557 Homo sapiens
TAX001136
Genes annotated by the GO term GO:0019239. Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3). (more detail) 14 NA Homo sapiens
TAX025406
GO:0046036 biological process CTP metabolic process The chemical reactions and pathways involving CTP, cytidine triphosphate. (more detail) 14 NA Homo sapiens
MOX003477
Genes associated with Computational Drug Signature Pazopanib Genes associated with Computational Drug Signature Pazopanib, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens
TAX016205
GO:0006241 biological process CTP biosynthetic process The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate. (more detail) 14 NA Homo sapiens
WIG000167
S1P4 pathway (more detail) 14 NA Homo sapiens
WAG000639
map kinase inactivation of smrt corepressor Corepressors are coregulators that interact with transcriptiol silencers in a variety of pathways su (more detail) 14 NA Homo sapiens
MEX000147
Genes associated with Approved Drug gemfibrozil Genes associated with Approved Drug gemfibrozil, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
WIG000766
Genes involved in Common Pathway (more detail) 14 NA Homo sapiens
TAX015222
GO:0004559 molecular function alpha mannosidase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides (more detail) 14 NA Homo sapiens
MOX004317
Genes associated with Computational Drug Signature mestranol Genes associated with Computational Drug Signature mestranol, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens
TAX019700
GO:0019372 biological process lipoxygenase pathway The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or (more detail) 14 NA Homo sapiens
MEX000169
Genes associated with Approved Drug indapamide Genes associated with Approved Drug indapamide, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX000824
Genes associated with Approved Drug griseofulvin Genes associated with Approved Drug griseofulvin, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
WIG001410
Irinotecan Pathway, Pharmacodynamics Model non-tissue specific cancer cell displaying genes which may be involved in the irinotecan pathw (more detail) 14 NA Homo sapiens
WIG000676
Genes involved in Acyl chain remodelling of PI (more detail) 14 NA Homo sapiens
WIG000272
Ca++/ Calmodulin dependent Protein Kinase Activation The calcium/calmodulin-dependent kinases (CaMKs) are involved in a large number of cellular response (more detail) 14 NA Homo sapiens
TAX019141
GO:0016641 molecular function oxidoreductase activity, acting on the CH NH2 group of donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or e (more detail) 16 NA Homo sapiens
MOX001423
Genes associated with Computational Drug Signature phthalic acid Genes associated with Computational Drug Signature phthalic acid, curated by the Drug Signature Data (more detail) 16 25990557 Homo sapiens
WIG002027
Estrogen metabolism Estrogen metabolism (more detail) 16 NA Homo sapiens
WAG000423
human cytomegalovirus and map kinase pathways To replicate in the host cell, viruses commandeer cellular sigling pathways. Cytomegalovirus (CMV) i (more detail) 16 NA Homo sapiens
MOX007471
Genes associated with Computational Drug Signature Canertinib dihydrochloride Genes associated with Computational Drug Signature Canertinib dihydrochloride, curated by the Drug S (more detail) 16 25990557 Homo sapiens
MOX001547
Genes associated with Computational Drug Signature trequinsin Genes associated with Computational Drug Signature trequinsin, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens
MOX015954
Genes associated with Computational Drug Signature Ziprasidone Genes associated with Computational Drug Signature Ziprasidone, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens
GEX001179
neural tube defects neural tube defects associated genes. PAGER constructed this gene set by grouping all genes which ar (more detail) 16 NA Homo sapiens
WIG000675
Genes involved in Acyl chain remodelling of PG (more detail) 16 NA Homo sapiens
MEX000042
Genes associated with Approved Drug azathioprine Genes associated with Approved Drug azathioprine, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
MEX000237
Genes associated with Approved Drug nimodipine Genes associated with Approved Drug nimodipine, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
WIG000042
DNA PK pathway in nonhomologous end joining (more detail) 16 NA Homo sapiens
TAX026500
GO:0050664 molecular function oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or el (more detail) 16 NA Homo sapiens
WAG000034
Glypican 1 network (more detail) 16 NA Homo sapiens
MOX011932
Genes associated with Computational Drug Signature chlorpromazine Genes associated with Computational Drug Signature chlorpromazine, curated by the Drug Signature Dat (more detail) 16 25990557 Homo sapiens
MEX000118
Genes associated with Approved Drug ethoxzolamide Genes associated with Approved Drug ethoxzolamide, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
MOX005520
Genes associated with Computational Drug Signature 172889 27 9 Genes associated with Computational Drug Signature 172889-27-9, curated by the Drug Signature Databa (more detail) 16 25990557 Homo sapiens
TAX029713
GO:0071871 biological process response to epinephrine Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 16 NA Homo sapiens
IEI014005
Protein protein interactors of human gene TNFRSF11A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNFRSF11A (SwissProt (more detail) 16 17535438 Homo sapiens
IEI004550
Protein protein interactors of human gene FAM86B2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM86B2 (SwissProt I (more detail) 16 17535438 Homo sapiens
MEX002078
Genes associated with Kinase Inhibitor Kinome 2052 Genes associated with Kinase Inhibitor Kinome_2052, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001793
Genes associated with Kinase Inhibitor CHEMBL1979577 Genes associated with Kinase Inhibitor CHEMBL1979577, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MOX005434
Genes associated with Computational Drug Signature 1 NM PP1 Genes associated with Computational Drug Signature 1-NM-PP1, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens
MOX002838
Genes associated with Computational Drug Signature CTK2F5402 Genes associated with Computational Drug Signature CTK2F5402, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens
TAX015558
GO:0005024 molecular function transforming growth factor beta activated receptor activity Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side (more detail) 9 NA Homo sapiens
MOX012536
Genes associated with Computational Drug Signature Enzastaurin Genes associated with Computational Drug Signature Enzastaurin, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
MEX001289
Genes associated with Kinase Inhibitor SU11274 Genes associated with Kinase Inhibitor SU11274, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001888
Genes associated with Kinase Inhibitor Oxindole Based Inhibitor 54 Genes associated with Kinase Inhibitor Oxindole-Based Inhibitor 54, curated by the Drug Signature Da (more detail) 9 25990557 Homo sapiens
MEX001563
Genes associated with Kinase Inhibitor Kinome 2079 Genes associated with Kinase Inhibitor Kinome_2079, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002231
Genes associated with Kinase Inhibitor 1 NM PP1 Genes associated with Kinase Inhibitor 1-NM-PP1, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002191
Genes associated with Kinase Inhibitor CHEMBL241517 Genes associated with Kinase Inhibitor CHEMBL241517, curated by the Drug Signature Database (DSigDB) (more detail) 9 25990557 Homo sapiens
MEX000151
Genes associated with Approved Drug glyburide Genes associated with Approved Drug glyburide, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
TAX017328
GO:0008525 molecular function phosphatidylcholine transporter activity Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells (more detail) 9 NA Homo sapiens
TAX014916
GO:0004017 molecular function adenylate kinase activity Catalysis of the reaction: ATP + AMP = 2 ADP. (more detail) 9 NA Homo sapiens
PEX002570
zf RING 2: Ring finger domain (more detail) 9 NA Homo sapiens
MOX014196
Genes associated with Computational Drug Signature nu6102 Genes associated with Computational Drug Signature nu6102, curated by the Drug Signature Database (D (more detail) 9 25990557 Homo sapiens
WAG000658
nitric oxide signaling pathway Glutamatergic-mediated nitric oxide (NO) production occurs via the N-methyl-D-aspartic acid (NMDA) p (more detail) 9 NA Homo sapiens
MEX001449
Genes associated with Kinase Inhibitor CHEMBL47203 Genes associated with Kinase Inhibitor CHEMBL47203, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002310
Genes associated with Kinase Inhibitor Tozasertib Genes associated with Kinase Inhibitor Tozasertib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002033
Genes associated with Kinase Inhibitor Sorafenib Genes associated with Kinase Inhibitor Sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002183
Genes associated with Kinase Inhibitor PDGF Receptor Tyrosine Kinase Inhibitor V Genes associated with Kinase Inhibitor PDGF Receptor Tyrosine Kinase Inhibitor V, curated by the Dru (more detail) 9 25990557 Homo sapiens
MOX002712
Genes associated with Computational Drug Signature 7 Hydroxy 4 (trifluoromethyl)coumarin Genes associated with Computational Drug Signature 7-Hydroxy-4-(trifluoromethyl)coumarin, curated by (more detail) 9 25990557 Homo sapiens
TAX017531
GO:0009133 biological process nucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compou (more detail) 9 NA Homo sapiens
MEX001403
Genes associated with Kinase Inhibitor NCGC00346961 01 Genes associated with Kinase Inhibitor NCGC00346961-01, curated by the Drug Signature Database (DSig (more detail) 9 25990557 Homo sapiens
MEX001354
Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002218
Genes associated with Kinase Inhibitor BX 517 Genes associated with Kinase Inhibitor BX-517, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MOX000229
Genes associated with Computational Drug Signature Ajmalicine hydrochloride Genes associated with Computational Drug Signature Ajmalicine hydrochloride, curated by the Drug Sig (more detail) 9 25990557 Homo sapiens
MOX013420
Genes associated with Computational Drug Signature leucettamine B Genes associated with Computational Drug Signature leucettamine B, curated by the Drug Signature Dat (more detail) 9 25990557 Homo sapiens
TAX021309
GO:0032052 molecular function bile acid binding Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic aci (more detail) 9 NA Homo sapiens
TAX017606
GO:0009215 biological process purine deoxyribonucleoside triphosphate metabolic process The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound co (more detail) 9 NA Homo sapiens
TAX025943
GO:0047498 molecular function calcium dependent phospholipase A2 activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. (more detail) 9 NA Homo sapiens
TAX032187
GO:1901612 molecular function cardiolipin binding Interacting selectively and non-covalently with cardiolipin. (more detail) 9 NA Homo sapiens
PEX001840
EphA2 TM: Ephrin type A receptor 2 transmembrane domain Epha2_TM represents the left-handed dimer transmembrane domain of of EphA2 receptor. This domain ol (more detail) 9 NA Homo sapiens
MOX012169
Genes associated with Computational Drug Signature dantrolene Genes associated with Computational Drug Signature dantrolene, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens
TAX001241
Genes annotated by the GO term GO:0004709. Catalysis of the phosphorylation and activation of MAP kinase kinases; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases. (more detail) 9 NA Homo sapiens
MEX001372
Genes associated with Kinase Inhibitor Kinome 1335 Genes associated with Kinase Inhibitor Kinome_1335, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001049
Genes associated with Approved Drug sunitinib malate Genes associated with Approved Drug sunitinib malate, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MEX001887
Genes associated with Kinase Inhibitor aminopurvalanol A Genes associated with Kinase Inhibitor aminopurvalanol A, curated by the Drug Signature Database (DS (more detail) 9 25990557 Homo sapiens
MEX002402
Genes associated with Kinase Inhibitor Lapatinib Genes associated with Kinase Inhibitor Lapatinib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002068
Genes associated with Kinase Inhibitor BX 320 Genes associated with Kinase Inhibitor BX-320, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002147
Genes associated with Kinase Inhibitor CHEMBL1979883 Genes associated with Kinase Inhibitor CHEMBL1979883, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MEX001211
Genes associated with Kinase Inhibitor purvalanol A Genes associated with Kinase Inhibitor purvalanol A, curated by the Drug Signature Database (DSigDB) (more detail) 9 25990557 Homo sapiens
MOX007345
Genes associated with Computational Drug Signature BMS 754807 Genes associated with Computational Drug Signature BMS-754807, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens
MOX012943
Genes associated with Computational Drug Signature GTPL21 Genes associated with Computational Drug Signature GTPL21, curated by the Drug Signature Database (D (more detail) 9 25990557 Homo sapiens
TAX030481
GO:0090308 biological process regulation of methylation dependent chromatin silencing Any process that modulates the rate, frequency, or extent of the repression of transcription by meth (more detail) 9 NA Homo sapiens
TAX019181
GO:0016725 molecular function oxidoreductase activity, acting on CH or CH2 groups Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or elec (more detail) 9 NA Homo sapiens
PEX002330
ArfGap: Putative GTPase activating protein for Arf Putative zinc fingers with GTPase activating proteins (GAPs) towards the small GTPase, Arf. The GAP (more detail) 9 NA Homo sapiens
MOX014421
Genes associated with Computational Drug Signature pergolide Genes associated with Computational Drug Signature pergolide, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens
FEX000430
Breast Park06 11genes ABC transporters Table 2. Differentially expressed ABC transporters ordered by significance (more detail) 9 16752223 Homo sapiens
WIG001347
Erlotinib Pathway, Pharmacokinetics Model human liver cell showing genes involved in the transportation and metabolism of Erlotinib. (more detail) 9 NA Homo sapiens
MEX001433
Genes associated with Kinase Inhibitor S1107 Selleck Genes associated with Kinase Inhibitor S1107_Selleck, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MEX001377
Genes associated with Kinase Inhibitor Kinome 468 Genes associated with Kinase Inhibitor Kinome_468, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001380
Genes associated with Kinase Inhibitor lfm a13 Genes associated with Kinase Inhibitor lfm-a13, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002119
Genes associated with Kinase Inhibitor GW809897X Genes associated with Kinase Inhibitor GW809897X, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
TAX014994
GO:0004126 molecular function cytidine deaminase activity Catalysis of the reaction: cytidine + H2O = uridine + NH3. (more detail) 9 NA Homo sapiens
TAX017263
GO:0008429 molecular function phosphatidylethanolamine binding Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerop (more detail) 9 NA Homo sapiens
TAX016183
GO:0006198 biological process cAMP catabolic process The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, a (more detail) 9 NA Homo sapiens
TAX015321
GO:0004690 molecular function cyclic nucleotide dependent protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the pres (more detail) 9 NA Homo sapiens
MOX012197
Genes associated with Computational Drug Signature Debromohymenialdisine Genes associated with Computational Drug Signature Debromohymenialdisine, curated by the Drug Signat (more detail) 9 25990557 Homo sapiens
WAG000929
Removal of aminoterminal propeptides from gamma carboxylated proteins (more detail) 9 NA Homo sapiens
MEX001398
Genes associated with Kinase Inhibitor JNK Inhibitor V Genes associated with Kinase Inhibitor JNK Inhibitor V, curated by the Drug Signature Database (DSig (more detail) 9 25990557 Homo sapiens
MEX001911
Genes associated with Kinase Inhibitor ML 9 Genes associated with Kinase Inhibitor ML-9, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002000
Genes associated with Kinase Inhibitor CHEMBL1993941 Genes associated with Kinase Inhibitor CHEMBL1993941, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MEX001691
Genes associated with Kinase Inhibitor Kinome 413 Genes associated with Kinase Inhibitor Kinome_413, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002104
Genes associated with Kinase Inhibitor PF 477736 Genes associated with Kinase Inhibitor PF-477736, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MOX002520
Genes associated with Computational Drug Signature Risedronate Genes associated with Computational Drug Signature Risedronate, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
MOX008615
Genes associated with Computational Drug Signature CHEMBL204357 Genes associated with Computational Drug Signature CHEMBL204357, curated by the Drug Signature Datab (more detail) 9 25990557 Homo sapiens
TAX016398
GO:0006531 biological process aspartate metabolic process The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-ami (more detail) 9 NA Homo sapiens
TAX014794
GO:0003810 molecular function protein glutamine gamma glutamyltransferase activity Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This re (more detail) 9 NA Homo sapiens
MEX001374
Genes associated with Kinase Inhibitor CHEMBL411903 Genes associated with Kinase Inhibitor CHEMBL411903, curated by the Drug Signature Database (DSigDB) (more detail) 9 25990557 Homo sapiens
MEX002121
Genes associated with Kinase Inhibitor CHEMBL2062937 Genes associated with Kinase Inhibitor CHEMBL2062937, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MEX001823
Genes associated with Kinase Inhibitor GW843682X Genes associated with Kinase Inhibitor GW843682X, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MOX001487
Genes associated with Computational Drug Signature Dipentyl phthalate Genes associated with Computational Drug Signature Dipentyl phthalate, curated by the Drug Signature (more detail) 9 25990557 Homo sapiens
TAX020972
GO:0031404 molecular function chloride ion binding Interacting selectively and non-covalently with chloride ions (Cl-). (more detail) 9 NA Homo sapiens
PEX000235
HATPase c: Histidine kinase , DNA gyrase B , and HSP90 like ATPase This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and (more detail) 9 NA Homo sapiens
FEX001900
Lung Yabuki07 10genes Table 4. ABC transporter genes highly expressed in drug-resistant cell line NCI-H460/PTX250 relative (more detail) 9 17284363 Homo sapiens
TAX023761
GO:0042301 molecular function phosphate ion binding Interacting selectively and non-covalently with phosphate. (more detail) 9 NA Homo sapiens
WAG001367
Ribonucleotide salvage (more detail) 9 NA Homo sapiens
MEX001253
Genes associated with Kinase Inhibitor Kinome 242 Genes associated with Kinase Inhibitor Kinome_242, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001901
Genes associated with Kinase Inhibitor Kinome 709 Genes associated with Kinase Inhibitor Kinome_709, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
IEI014053
Protein protein interactors of human gene TNP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNP1 (SwissProt ID=P (more detail) 9 17535438 Homo sapiens
IEI011435
Protein protein interactors of human gene RNF26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF26 (SwissProt ID= (more detail) 9 17535438 Homo sapiens
IEI000711
Protein protein interactors of human gene APBB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APBB3 (SwissProt ID= (more detail) 9 17535438 Homo sapiens
IEI007230
Protein protein interactors of human gene LGALS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LGALS2 (SwissProt ID (more detail) 11 17535438 Homo sapiens
TAX024234
GO:0043225 molecular function ATPase coupled anion transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to th (more detail) 11 NA Homo sapiens
MOX014544
Genes associated with Computational Drug Signature Pirinixic acid Genes associated with Computational Drug Signature Pirinixic acid, curated by the Drug Signature Dat (more detail) 11 25990557 Homo sapiens
GEX001017
liver cancer liver cancer associated genes. PAGER constructed this gene set by grouping all genes which are assoc (more detail) 11 NA Homo sapiens
MEX000894
Genes associated with Approved Drug tiotixene Genes associated with Approved Drug tiotixene, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX000334
Genes associated with Approved Drug trichlormethiazide Genes associated with Approved Drug trichlormethiazide, curated by the Drug Signature Database (DSig (more detail) 11 25990557 Homo sapiens
MEX000623
Genes associated with Approved Drug zileuton Genes associated with Approved Drug zileuton, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MOX000403
Genes associated with Computational Drug Signature PHENTHOATE Genes associated with Computational Drug Signature PHENTHOATE, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens
MOX005071
Genes associated with Computational Drug Signature fluorescein Genes associated with Computational Drug Signature fluorescein, curated by the Drug Signature Databa (more detail) 11 25990557 Homo sapiens
TAX026889
GO:0051238 biological process sequestering of metal ion The process of binding or confining metal ions such that they are separated from other components of (more detail) 11 NA Homo sapiens
TAX001108
Genes annotated by the GO term GO:0004180. Catalysis of the hydrolytic cleavage of the terminal or penultimate peptide bond at the C terminal end of a peptide or polypeptide. (more detail) 11 NA Homo sapiens
WIG001360
Benzodiazepine Pathway, Pharmacokinetics Benzodiazepine Pathway, Pharmacokinetics (more detail) 11 NA Homo sapiens
MEX000232
Genes associated with Approved Drug nevirapine Genes associated with Approved Drug nevirapine, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MOX013109
Genes associated with Computational Drug Signature IMAZODAN Genes associated with Computational Drug Signature IMAZODAN, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens
TAX017559
GO:0009162 biological process deoxyribonucleoside monophosphate metabolic process The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consis (more detail) 11 NA Homo sapiens
TAX017810
GO:0009931 molecular function calcium dependent protein serine/threonine kinase activity Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a pro (more detail) 11 NA Homo sapiens
MOX001039
Genes associated with Computational Drug Signature PROFENOFOS Genes associated with Computational Drug Signature PROFENOFOS, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens
MOX004349
Genes associated with Computational Drug Signature 4,4' METHYLENEBIS(2 CHLOROANILINE) Genes associated with Computational Drug Signature 4,4'-METHYLENEBIS(2-CHLOROANILINE), curated by th (more detail) 11 25990557 Homo sapiens
TAX019234
GO:0016813 molecular function hydrolase activity, acting on carbon nitrogen (but not peptide) bonds, in linear amidines Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound (more detail) 11 NA Homo sapiens
WIG000308
Map Kinase Inactivation of SMRT Corepressor Corepressors are coregulators that interact with transcriptional silencers in a variety of pathways (more detail) 11 NA Homo sapiens
PEX002226
Globin: Globin (more detail) 11 NA Homo sapiens
TAX031324
GO:0099133 biological process ATP hydrolysis coupled anion transmembrane transport The transport of an inorganic anion across a membrane and against an electrochemical gradient, using (more detail) 11 NA Homo sapiens
MOX001119
Genes associated with Computational Drug Signature 15(S) HETE d8 Genes associated with Computational Drug Signature 15(S)-HETE-d8, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens
MEX000395
Genes associated with Approved Drug cephalothin Genes associated with Approved Drug cephalothin, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX000630
Genes associated with Approved Drug gemcitabine hydrochloride Genes associated with Approved Drug gemcitabine hydrochloride, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens
MEX001674
Genes associated with Kinase Inhibitor InSolution¿¿KT5720 Genes associated with Kinase Inhibitor InSolution¿¿KT5720, curated by the Drug Signa (more detail) 11 25990557 Homo sapiens
IEI010099
Protein protein interactors of human gene PLK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLK3 (SwissProt ID=Q (more detail) 17 17535438 Homo sapiens
TAX024200
GO:0043174 biological process nucleoside salvage Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucl (more detail) 17 NA Homo sapiens
IEI015826
Protein protein interactors of human gene ZNRF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNRF1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens
IEI007716
Protein protein interactors of human gene MARCHF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MARCHF7 (SwissProt I (more detail) 17 17535438 Homo sapiens
IEI006539
Protein protein interactors of human gene ITGB1BP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ITGB1BP1 (SwissProt (more detail) 17 17535438 Homo sapiens
IEI000750
Protein protein interactors of human gene APOH from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene APOH (SwissProt ID=P (more detail) 17 17535438 Homo sapiens
TAX020754
GO:0031000 biological process response to caffeine Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 17 NA Homo sapiens
MOX002222
Genes associated with Computational Drug Signature calphostin C Genes associated with Computational Drug Signature calphostin C, curated by the Drug Signature Datab (more detail) 17 25990557 Homo sapiens
TAX018918
GO:0016226 biological process iron sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster. (more detail) 17 NA Homo sapiens
TAX020267
GO:0030033 biological process microvillus assembly Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. (more detail) 17 NA Homo sapiens
MOX018086
Genes associated with Computational Drug Signature Vandetanib Genes associated with Computational Drug Signature Vandetanib, curated by the Drug Signature Databas (more detail) 17 25990557 Homo sapiens
TAX001061
Genes annotated by the GO term GO:0042166. Interacting selectively with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. (more detail) 17 NA Homo sapiens
MEX000233
Genes associated with Approved Drug nicardipine Genes associated with Approved Drug nicardipine, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
TAX027554
GO:0055070 biological process copper ion homeostasis Any process involved in the maintenance of an internal steady state of copper ions within an organis (more detail) 17 NA Homo sapiens
GEX001228
oral cancer oral cancer associated genes. PAGER constructed this gene set by grouping all genes which are associ (more detail) 17 NA Homo sapiens
WIG000339
Human Cytomegalovirus and Map Kinase Pathways To replicate in the host cell, viruses commandeer cellular signaling pathways. Cytomegalovirus (CMV) (more detail) 17 NA Homo sapiens
WIG001389
Mycophenolic acid Pathway, Pharmacokinetics/Pharmacodynamics Schematic representation of mycophenolic acid metabolism. (more detail) 17 NA Homo sapiens
MOX002790
Genes associated with Computational Drug Signature bisindolylmaleimide iv Genes associated with Computational Drug Signature bisindolylmaleimide iv, curated by the Drug Signa (more detail) 17 25990557 Homo sapiens
MOX004606
Genes associated with Computational Drug Signature pyrilamine Genes associated with Computational Drug Signature pyrilamine, curated by the Drug Signature Databas (more detail) 17 25990557 Homo sapiens
WAG001629
D Glutamine and D glutamate metabolism (more detail) 17 NA Homo sapiens
TAX020846
GO:0031163 biological process metallo sulfur cluster assembly The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster. (more detail) 17 NA Homo sapiens
WAG001238
role of nicotinic acetylcholine receptors in the regulation of apoptosis Nicotinic acetylcholine receptors are essential for neuromuscular sigling and are also expressed in (more detail) 17 NA Homo sapiens
GEX166741
LDL cholesterol Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (more detail) 17 19060911 Homo sapiens
TAX023315
GO:0036270 biological process response to diuretic Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 17 NA Homo sapiens
MOX004495
Genes associated with Computational Drug Signature pergolide Genes associated with Computational Drug Signature pergolide, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens
MAX001083
Genes down regulated in MDA MB 231 cells (breast cancer, mutated TP53 [GeneID=7157] ) undergoing mitotic arrest and apoptosis after treatment with 100 nM docetaxel [PubChem=148124] . Among microtubule-targeting agents, docetaxel has received recent interest owing to its good therape (more detail) 17 NA Homo sapiens
MOX013108
Genes associated with Computational Drug Signature Imatinib Genes associated with Computational Drug Signature Imatinib, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens
MOX004628
Genes associated with Computational Drug Signature Rose bengale Genes associated with Computational Drug Signature Rose bengale, curated by the Drug Signature Datab (more detail) 17 25990557 Homo sapiens
GEX000094
anemia, sickle cell anemia, sickle cell associated genes. PAGER constructed this gene set by grouping all genes which ar (more detail) 17 NA Homo sapiens
TAX013968
GO:0001963 biological process synaptic transmission, dopaminergic The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent act (more detail) 15 NA Homo sapiens
MOX017432
Genes associated with Computational Drug Signature 5 METHOXYTRYPTAMINE Genes associated with Computational Drug Signature 5-METHOXYTRYPTAMINE, curated by the Drug Signatur (more detail) 15 25990557 Homo sapiens
MOX007135
Genes associated with Computational Drug Signature azathioprine Genes associated with Computational Drug Signature azathioprine, curated by the Drug Signature Datab (more detail) 15 25990557 Homo sapiens
WIG001330
Estrogen Metabolism Pathway Estrogen metabolism in the liver. (more detail) 15 NA Homo sapiens
TAX017512
GO:0009110 biological process vitamin biosynthetic process The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unre (more detail) 15 NA Homo sapiens
TAX018786
GO:0015923 molecular function mannosidase activity Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cycl (more detail) 15 NA Homo sapiens
TAX018797
GO:0015936 biological process coenzyme A metabolic process The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')panta (more detail) 15 NA Homo sapiens
TAX015216
GO:0004551 molecular function nucleotide diphosphatase activity Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides. (more detail) 15 NA Homo sapiens
WIG000266
Roles of fl arrestin dependent Recruitment of Src Kinases in GPCR Signaling The binding of -arrestins to agonist-occupied GPCRs coincides with the recruitment of Src family tyr (more detail) 15 NA Homo sapiens
MOX004340
Genes associated with Computational Drug Signature 5 METHOXYTRYPTAMINE Genes associated with Computational Drug Signature 5-METHOXYTRYPTAMINE, curated by the Drug Signatur (more detail) 15 25990557 Homo sapiens
TAX017527
GO:0009129 biological process pyrimidine nucleoside monophosphate metabolic process The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consis (more detail) 15 NA Homo sapiens
TAX016452
GO:0006586 biological process indolalkylamine metabolic process The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives contain (more detail) 15 NA Homo sapiens
WIG001189
Genes involved in SHC1 events in EGFR signaling (more detail) 15 NA Homo sapiens
MEX000144
Genes associated with Approved Drug furosemide Genes associated with Approved Drug furosemide, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
TAX027031
GO:0051481 biological process negative regulation of cytosolic calcium ion concentration Any process that decreases the concentration of calcium ions in the cytosol. (more detail) 15 NA Homo sapiens
MOX012722
Genes associated with Computational Drug Signature FLUOXETINE HYDROCHLORIDE Genes associated with Computational Drug Signature FLUOXETINE HYDROCHLORIDE, curated by the Drug Sig (more detail) 15 25990557 Homo sapiens
WIG001365
Doxorubicin Pathway (Cardiomyocyte Cell), Pharmacodynamics Representation of the candidate genes involved in adverse effects of doxorubicin in a stylized cardi (more detail) 15 NA Homo sapiens
MOX004189
Genes associated with Computational Drug Signature 4 Hexylresorcinol Genes associated with Computational Drug Signature 4-Hexylresorcinol, curated by the Drug Signature (more detail) 15 25990557 Homo sapiens
IEI011434
Protein protein interactors of human gene RNF25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF25 (SwissProt ID= (more detail) 15 17535438 Homo sapiens
IEI010345
Protein protein interactors of human gene PPP1R13L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R13L (SwissProt (more detail) 13 17535438 Homo sapiens
IEI014320
Protein protein interactors of human gene TRPC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRPC6 (SwissProt ID= (more detail) 13 17535438 Homo sapiens
TAX024182
GO:0043142 molecular function single stranded DNA dependent ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of singl (more detail) 13 NA Homo sapiens
TAX022449
GO:0034374 biological process low density lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particl (more detail) 13 NA Homo sapiens
TAX034843
GO:2000651 biological process positive regulation of sodium ion transmembrane transporter activity Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane tr (more detail) 13 NA Homo sapiens
MOX002394
Genes associated with Computational Drug Signature SERTINDOLE Genes associated with Computational Drug Signature SERTINDOLE, curated by the Drug Signature Databas (more detail) 13 25990557 Homo sapiens
TAX032025
GO:1901160 biological process primary amino compound metabolic process The chemical reactions and pathways involving primary amino compound. (more detail) 13 NA Homo sapiens
TAX015211
GO:0004535 molecular function poly(A) specific ribonuclease activity Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP. (more detail) 13 NA Homo sapiens
FOX000641
Genes in the cancer module 326 (more detail) 13 NA Homo sapiens
MAX000819
Proteins identified by mass spectrometry in complexes containing ALKBH8 [GeneID=91801] . tRNA nucleosides are extensively modified to ensure their proper function in translation. However, m (more detail) 13 NA Homo sapiens
MEX000121
Genes associated with Approved Drug felbamate Genes associated with Approved Drug felbamate, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MOX016663
Genes associated with Computational Drug Signature methoxsalen Genes associated with Computational Drug Signature methoxsalen, curated by the Drug Signature Databa (more detail) 13 25990557 Homo sapiens
GEX166601
Triglycerides Newly identified loci that influence lipid concentrations and risk of coronary artery disease. (more detail) 13 18193043 Homo sapiens
TAX031998
GO:1901070 biological process guanosine containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (gu (more detail) 13 NA Homo sapiens
PEX000005
Carb anhydrase: Eukaryotic type carbonic anhydrase (more detail) 13 NA Homo sapiens
WIG001268
Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (more detail) 13 NA Homo sapiens
MOX002178
Genes associated with Computational Drug Signature CHEBI:71224 Genes associated with Computational Drug Signature CHEBI:71224, curated by the Drug Signature Databa (more detail) 13 25990557 Homo sapiens
MEX002661
Genes associated with Perturbagen Signature BCB000039 Genes associated with Perturbagen Signature BCB000039, curated by the Drug Signature Database (DSigD (more detail) 13 25990557 Homo sapiens
TAX001304
Genes annotated by the GO term GO:0004623. Catalysis of the reaction: phosphatidylcholine + H2O = 1 acylglycerophosphocholine + a carboxylate. (more detail) 13 NA Homo sapiens
TAX018087
GO:0010745 biological process negative regulation of macrophage derived foam cell differentiation Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentia (more detail) 13 NA Homo sapiens
TAX031261
GO:0098993 cellular component anchored component of synaptic vesicle membrane The component of the synaptic vesicle membrane consisting of the gene products that are tethered to (more detail) 13 NA Homo sapiens
MOX014367
Genes associated with Computational Drug Signature Pazopanib Genes associated with Computational Drug Signature Pazopanib, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens
MEX001627
Genes associated with Kinase Inhibitor GW770249X Genes associated with Kinase Inhibitor GW770249X, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MOX009479
Genes associated with Computational Drug Signature CHEMBL292495 Genes associated with Computational Drug Signature CHEMBL292495, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens
PEX000542
Acyl CoA dh N: Acyl CoA dehydrogenase, N terminal domain The N-terminal domain of Acyl-CoA dehydrogenase is an all-alpha domain. (more detail) 8 NA Homo sapiens
MOX012715
Genes associated with Computational Drug Signature flunisolide Genes associated with Computational Drug Signature flunisolide, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
WAG000816
Atrazine degradation (more detail) 8 NA Homo sapiens
MEX001462
Genes associated with Kinase Inhibitor SU9516 Genes associated with Kinase Inhibitor SU9516, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MOX006316
Genes associated with Computational Drug Signature 693228 63 6 Genes associated with Computational Drug Signature 693228-63-6, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
TAX023356
GO:0036353 biological process histone H2A K119 monoubiquitination The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in (more detail) 8 NA Homo sapiens
TAX013720
GO:0001591 molecular function dopamine neurotransmitter receptor activity, coupled via Gi/Go Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go (more detail) 8 NA Homo sapiens
TAX014903
GO:0003996 molecular function acyl CoA ligase activity Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-Co (more detail) 8 NA Homo sapiens
MOX011633
Genes associated with Computational Drug Signature CHEMBL608532 Genes associated with Computational Drug Signature CHEMBL608532, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens
MOX014069
Genes associated with Computational Drug Signature norfloxacin Genes associated with Computational Drug Signature norfloxacin, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
MOX002811
Genes associated with Computational Drug Signature DIHEPTYL PHTHALATE Genes associated with Computational Drug Signature DIHEPTYL PHTHALATE, curated by the Drug Signature (more detail) 8 25990557 Homo sapiens
MOX004546
Genes associated with Computational Drug Signature piribedil Genes associated with Computational Drug Signature piribedil, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
TAX017596
GO:0009204 biological process deoxyribonucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate (more detail) 8 NA Homo sapiens
TAX021562
GO:0032453 molecular function histone demethylase activity (H3 K4 specific) Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein. (more detail) 8 NA Homo sapiens
TAX001313
Genes annotated by the GO term GO:0016849. (more detail) 8 NA Homo sapiens
WIG001338
Gefitinib Pathway, Pharmacokinetics Representation of the candidate genes involved in the transportation and metabolism of gefitinib. (more detail) 8 NA Homo sapiens
MEX001325
Genes associated with Kinase Inhibitor Kinome 463 Genes associated with Kinase Inhibitor Kinome_463, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX002309
Genes associated with Kinase Inhibitor Kinome 203 Genes associated with Kinase Inhibitor Kinome_203, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001657
Genes associated with Kinase Inhibitor Kinome 3177 Genes associated with Kinase Inhibitor Kinome_3177, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001547
Genes associated with Kinase Inhibitor 732983 37 8 Genes associated with Kinase Inhibitor 732983-37-8, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001586
Genes associated with Kinase Inhibitor Cdk4 Inhibitor Genes associated with Kinase Inhibitor Cdk4 Inhibitor, curated by the Drug Signature Database (DSigD (more detail) 8 25990557 Homo sapiens
MEX002272
Genes associated with Kinase Inhibitor Kinome 876 Genes associated with Kinase Inhibitor Kinome_876, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX002351
Genes associated with Kinase Inhibitor 406209 26 5 Genes associated with Kinase Inhibitor 406209-26-5, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001480
Genes associated with Kinase Inhibitor Src Kinase Inhibitor I Genes associated with Kinase Inhibitor Src Kinase Inhibitor I, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
MEX002257
Genes associated with Kinase Inhibitor 4 anilinopyrimidine 8c Genes associated with Kinase Inhibitor 4-anilinopyrimidine 8c, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
MEX001470
Genes associated with Kinase Inhibitor Kinome 258 Genes associated with Kinase Inhibitor Kinome_258, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MOX004787
Genes associated with Computational Drug Signature TROLEANDOMYCIN Genes associated with Computational Drug Signature TROLEANDOMYCIN, curated by the Drug Signature Dat (more detail) 8 25990557 Homo sapiens
TAX022851
GO:0035381 molecular function ATP gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the (more detail) 8 NA Homo sapiens
TAX020398
GO:0030235 molecular function nitric oxide synthase regulator activity Modulates the activity of nitric oxide synthase. (more detail) 8 NA Homo sapiens
PEX000414
zf RanBP: Zn finger in Ran binding protein and others (more detail) 8 NA Homo sapiens
PEX002086
zf CXXC: CXXC zinc finger domain This domain contains eight conserved cysteine residues that bind to two zinc ions. The CXXC domain (more detail) 8 NA Homo sapiens
WAG000300
Gamma carboxylation, transport, and amino terminal cleavage of proteins (more detail) 8 NA Homo sapiens
MEX001241
Genes associated with Kinase Inhibitor Kinome 77 Genes associated with Kinase Inhibitor Kinome_77, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001264
Genes associated with Kinase Inhibitor SB 747651A Genes associated with Kinase Inhibitor SB-747651A, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001319
Genes associated with Kinase Inhibitor CHEMBL592030 Genes associated with Kinase Inhibitor CHEMBL592030, curated by the Drug Signature Database (DSigDB) (more detail) 8 25990557 Homo sapiens
MEX001338
Genes associated with Kinase Inhibitor 5Z 7 Oxozeaenol Genes associated with Kinase Inhibitor 5Z-7-Oxozeaenol, curated by the Drug Signature Database (DSig (more detail) 8 25990557 Homo sapiens
MEX002242
Genes associated with Kinase Inhibitor Kinome 3566 Genes associated with Kinase Inhibitor Kinome_3566, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001609
Genes associated with Kinase Inhibitor 2zv2 Genes associated with Kinase Inhibitor 2zv2, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX002140
Genes associated with Kinase Inhibitor Vatalanib Genes associated with Kinase Inhibitor Vatalanib, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MOX000295
Genes associated with Computational Drug Signature bromperidol Genes associated with Computational Drug Signature bromperidol, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
MOX004918
Genes associated with Computational Drug Signature fluconazole Genes associated with Computational Drug Signature fluconazole, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
TAX017555
GO:0009157 biological process deoxyribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphat (more detail) 8 NA Homo sapiens
TAX021249
GO:0031956 molecular function medium chain fatty acid CoA ligase activity Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl- (more detail) 8 NA Homo sapiens
TAX018911
GO:0016208 molecular function AMP binding Interacting selectively and non-covalently with AMP, adenosine monophosphate. (more detail) 8 NA Homo sapiens
TAX014802
GO:0003831 molecular function beta N acetylglucosaminylglycopeptide beta 1,4 galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-g (more detail) 8 NA Homo sapiens
MOX014914
Genes associated with Computational Drug Signature Ruboxistaurin Genes associated with Computational Drug Signature Ruboxistaurin, curated by the Drug Signature Data (more detail) 8 25990557 Homo sapiens
TAX017329
GO:0008526 molecular function phosphatidylinositol transporter activity Enables the directed movement of phosphatidylinositol into, out of or within a cell, or between cell (more detail) 8 NA Homo sapiens
TAX026501
GO:0050665 biological process hydrogen peroxide biosynthetic process The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potent (more detail) 8 NA Homo sapiens
PEX001793
Acyl CoA dh M: Acyl CoA dehydrogenase, middle domain Central domain of Acyl-CoA dehydrogenase has a beta-barrel fold. (more detail) 8 NA Homo sapiens
PEX002505
F5 F8 type C: F5/8 type C domain This domain is also known as the discoidin (DS) domain family 1. (more detail) 8 NA Homo sapiens
MOX015025
Genes associated with Computational Drug Signature SC 44463 Genes associated with Computational Drug Signature SC-44463, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
MOX014153
Genes associated with Computational Drug Signature NSC160436 Genes associated with Computational Drug Signature NSC160436, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
MOX014852
Genes associated with Computational Drug Signature ro 32 0432 Genes associated with Computational Drug Signature ro 32-0432, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
WAG000016
rho selective guanine exchange factor akap13 mediates stress fiber formation The A-kise anchor protein 13 (AKAP13, also known as AKAP-LBC) is one of a group of structurally dive (more detail) 8 NA Homo sapiens
MEX001661
Genes associated with Kinase Inhibitor CGP 57380 Genes associated with Kinase Inhibitor CGP 57380, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001541
Genes associated with Kinase Inhibitor Bay 65 1942 hydrochloride Genes associated with Kinase Inhibitor Bay 65-1942 hydrochloride, curated by the Drug Signature Data (more detail) 8 25990557 Homo sapiens
MEX001920
Genes associated with Kinase Inhibitor GW784307A Genes associated with Kinase Inhibitor GW784307A, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001975
Genes associated with Kinase Inhibitor 1173900 33 8 Genes associated with Kinase Inhibitor 1173900-33-8, curated by the Drug Signature Database (DSigDB) (more detail) 8 25990557 Homo sapiens
MEX002300
Genes associated with Kinase Inhibitor GSK619487A Genes associated with Kinase Inhibitor GSK619487A, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MOX003434
Genes associated with Computational Drug Signature Lorcaserin Genes associated with Computational Drug Signature Lorcaserin, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
MOX003906
Genes associated with Computational Drug Signature cyproterone Genes associated with Computational Drug Signature cyproterone, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
MOX007443
Genes associated with Computational Drug Signature cabergoline Genes associated with Computational Drug Signature cabergoline, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
MOX012657
Genes associated with Computational Drug Signature Fasudil Genes associated with Computational Drug Signature Fasudil, curated by the Drug Signature Database ( (more detail) 8 25990557 Homo sapiens
TAX022635
GO:0034720 biological process histone H3 K4 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the his (more detail) 8 NA Homo sapiens
TAX016394
GO:0006527 biological process arginine catabolic process The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidami (more detail) 8 NA Homo sapiens
TAX019172
GO:0016713 molecular function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron sulfur protein as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred (more detail) 8 NA Homo sapiens
TAX019281
GO:0016885 molecular function ligase activity, forming carbon carbon bonds Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis (more detail) 8 NA Homo sapiens
PEX002015
Ephrin lbd: Ephrin receptor ligand binding domain The Eph receptors, which bind to ephrins Pfam:PF00812 are a large family of receptor tyrosine kinase (more detail) 8 NA Homo sapiens
PEX000706
PI3 PI4 kinase: Phosphatidylinositol 3 and 4 kinase Some members of this family probably do not have lipid kinase activity and are protein kinases, e.g. (more detail) 8 NA Homo sapiens
MEX001406
Genes associated with Kinase Inhibitor CHEMBL1967720 Genes associated with Kinase Inhibitor CHEMBL1967720, curated by the Drug Signature Database (DSigDB (more detail) 8 25990557 Homo sapiens
MEX001489
Genes associated with Kinase Inhibitor Kinome 458 Genes associated with Kinase Inhibitor Kinome_458, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MOX004333
Genes associated with Computational Drug Signature methomyl Genes associated with Computational Drug Signature methomyl, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
TAX022977
GO:0035608 biological process protein deglutamylation The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encode (more detail) 8 NA Homo sapiens
TAX023318
GO:0036289 biological process peptidyl serine autophosphorylation The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine r (more detail) 8 NA Homo sapiens
TAX030195
GO:0085020 biological process protein K6 linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine (more detail) 8 NA Homo sapiens
TAX013473
GO:0000733 biological process DNA strand renaturation The identification and annealing of complementary base pairs in single-strand DNA. (more detail) 8 NA Homo sapiens
TAX025980
GO:0047760 molecular function butyrate CoA ligase activity Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA. (more detail) 8 NA Homo sapiens
PEX000430
Acyl CoA dh 1: Acyl CoA dehydrogenase, C terminal domain C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle. (more detail) 8 NA Homo sapiens
PEX002016
JmjN: jmjN domain (more detail) 8 NA Homo sapiens
MOX012672
Genes associated with Computational Drug Signature ferulic acid Genes associated with Computational Drug Signature ferulic acid, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens
MOX015947
Genes associated with Computational Drug Signature ZILEUTON Genes associated with Computational Drug Signature ZILEUTON, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
TAX031502
GO:0102391 molecular function decanoate CoA ligase activity Catalysis of the reaction: decanoate + ATP(4-) + coenzyme A(4-) <=> decanoyl-CoA(4-) + AMP(2-) + dip (more detail) 8 NA Homo sapiens
TAX001126
Genes annotated by the GO term GO:0009975. Catalysis of a ring closure reaction. (more detail) 8 NA Homo sapiens
MEX000605
Genes associated with Approved Drug cabergoline Genes associated with Approved Drug cabergoline, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
WAG000128
Transport of gamma carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (more detail) 8 NA Homo sapiens
WIG001326
Warfarin Pathway, Pharmacokinetics Representation of the candidate genes involved in transport, metabolism and clearance of warfarin. (more detail) 8 NA Homo sapiens
MEX000728
Genes associated with Approved Drug flunisolide Genes associated with Approved Drug flunisolide, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX002316
Genes associated with Kinase Inhibitor GW693917A Genes associated with Kinase Inhibitor GW693917A, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
TAX024179
GO:0043139 molecular function 5' 3' DNA helicase activity Catalysis of the unwinding of the DNA helix in the direction 5' to 3'. (more detail) 8 NA Homo sapiens
IEI004896
Protein protein interactors of human gene FPR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FPR1 (SwissProt ID=P (more detail) 8 17535438 Homo sapiens
IEI007712
Protein protein interactors of human gene MARCHF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MARCHF3 (SwissProt I (more detail) 8 17535438 Homo sapiens
MOX015798
Genes associated with Computational Drug Signature Ursolic acid Genes associated with Computational Drug Signature Ursolic acid, curated by the Drug Signature Datab (more detail) 16 25990557 Homo sapiens
MOX001203
Genes associated with Computational Drug Signature AFLATOXIN G1 Genes associated with Computational Drug Signature AFLATOXIN G1, curated by the Drug Signature Datab (more detail) 16 25990557 Homo sapiens
MOX006275
Genes associated with Computational Drug Signature 6 bromo N (3 chlorophenyl)quinazolin 4 amine Genes associated with Computational Drug Signature 6-bromo-N-(3-chlorophenyl)quinazolin-4-amine, cur (more detail) 16 25990557 Homo sapiens
WIG000756
Genes involved in Chylomicron mediated lipid transport (more detail) 16 NA Homo sapiens
TAX001121
Genes annotated by the GO term GO:0050662. Interacting selectively with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. (more detail) 16 NA Homo sapiens
MOX016854
Genes associated with Computational Drug Signature piroxicam Genes associated with Computational Drug Signature piroxicam, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens
WIG001101
Genes involved in Pre NOTCH Processing in Golgi (more detail) 16 NA Homo sapiens
WAG000402
One carbon pool by folate (more detail) 16 NA Homo sapiens
TAX017849
GO:0010042 biological process response to manganese ion Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 16 NA Homo sapiens
TAX021398
GO:0032225 biological process regulation of synaptic transmission, dopaminergic Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the (more detail) 16 NA Homo sapiens
MEX000863
Genes associated with Approved Drug mycophenolic acid Genes associated with Approved Drug mycophenolic acid, curated by the Drug Signature Database (DSigD (more detail) 16 25990557 Homo sapiens
TAX000972
Genes annotated by the GO term GO:0016459. A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes. (more detail) 16 NA Homo sapiens
MOX002183
Genes associated with Computational Drug Signature 3,5 dinitrocatechol Genes associated with Computational Drug Signature 3,5-dinitrocatechol, curated by the Drug Signatur (more detail) 16 25990557 Homo sapiens
MOX013713
Genes associated with Computational Drug Signature miconazole Genes associated with Computational Drug Signature miconazole, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens
MOX017243
Genes associated with Computational Drug Signature linezolid Genes associated with Computational Drug Signature linezolid, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens
MOX004175
Genes associated with Computational Drug Signature HARMINE Genes associated with Computational Drug Signature HARMINE, curated by the Drug Signature Database ( (more detail) 16 25990557 Homo sapiens
TAX022357
GO:0034185 molecular function apolipoprotein binding Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipopr (more detail) 16 NA Homo sapiens
TAX025671
GO:0046625 molecular function sphingolipid binding Interacting selectively and non-covalently with sphingolipids, a class of lipids containing the long (more detail) 16 NA Homo sapiens
WIG000246
Role of nicotinic acetylcholine receptors in the regulation of apoptosis Nicotinic acetylcholine receptors are essential for neuromuscular signaling and are also expressed i (more detail) 16 NA Homo sapiens
WIG002039
Serotonin Receptor 2 and ELK SRF/GATA4 signaling Serotonin Receptor 2 and ELK-SRF/GATA4 signaling (more detail) 16 NA Homo sapiens
MOX013343
Genes associated with Computational Drug Signature L 741,626 Genes associated with Computational Drug Signature L-741,626, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens
TAX019229
GO:0016805 molecular function dipeptidase activity Catalysis of the hydrolysis of a dipeptide. (more detail) 16 NA Homo sapiens
TAX000332
Genes annotated by the GO term GO:0007131. The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity. (more detail) 16 NA Homo sapiens
MEX003101
Genes associated with Perturbagen Signature dyclonine Genes associated with Perturbagen Signature dyclonine, curated by the Drug Signature Database (DSigD (more detail) 16 25990557 Homo sapiens
MEX000196
Genes associated with Approved Drug mebendazole Genes associated with Approved Drug mebendazole, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
MOX000280
Genes associated with Computational Drug Signature p Propenylanisole Genes associated with Computational Drug Signature p-Propenylanisole, curated by the Drug Signature (more detail) 16 25990557 Homo sapiens
MOX006224
Genes associated with Computational Drug Signature 5 METHOXYTRYPTAMINE Genes associated with Computational Drug Signature 5-METHOXYTRYPTAMINE, curated by the Drug Signatur (more detail) 16 25990557 Homo sapiens
TAX023483
GO:0038084 biological process vascular endothelial growth factor signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF (more detail) 16 NA Homo sapiens
IEI002734
Protein protein interactors of human gene CNOT4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CNOT4 (SwissProt ID= (more detail) 16 17535438 Homo sapiens
IEI001335
Protein protein interactors of human gene BICD2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BICD2 (SwissProt ID= (more detail) 16 17535438 Homo sapiens
IEI010295
Protein protein interactors of human gene PPARGC1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPARGC1B (SwissProt (more detail) 16 17535438 Homo sapiens
IEI005012
Protein protein interactors of human gene GABRR1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GABRR1 (SwissProt ID (more detail) 16 17535438 Homo sapiens
IEI007618
Protein protein interactors of human gene MAML1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAML1 (SwissProt ID= (more detail) 16 17535438 Homo sapiens
IEI009853
Protein protein interactors of human gene PHF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PHF7 (SwissProt ID=Q (more detail) 16 17535438 Homo sapiens
IEI003834
Protein protein interactors of human gene DUSP10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DUSP10 (SwissProt ID (more detail) 16 17535438 Homo sapiens
IEI002187
Protein protein interactors of human gene CDC42BPA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC42BPA (SwissProt (more detail) 16 17535438 Homo sapiens
TAX028786
GO:0070189 biological process kynurenine metabolic process The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine. (more detail) 10 NA Homo sapiens
WEX000075
Nucleotide Synthesis The genes related to nucleotide synthesis (metabolism) in tumor, immune, stroma using next-generatio (more detail) 10 NA Homo sapiens
IEI010042
Protein protein interactors of human gene PLCE1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLCE1 (SwissProt ID= (more detail) 10 17535438 Homo sapiens
MOX007992
Genes associated with Computational Drug Signature CHEMBL119841 Genes associated with Computational Drug Signature CHEMBL119841, curated by the Drug Signature Datab (more detail) 10 25990557 Homo sapiens
TAX017642
GO:0009265 biological process 2' deoxyribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compou (more detail) 10 NA Homo sapiens
TAX017526
GO:0009128 biological process purine nucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a (more detail) 10 NA Homo sapiens
TAX023834
GO:0042428 biological process serotonin metabolic process The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotran (more detail) 10 NA Homo sapiens
WAG000847
protein kinase a at the centrosome Protein kise A regulatory subunit RIIalpha (PKA-RIIa) is tightly bound to centrosomal structures dur (more detail) 10 NA Homo sapiens
FOX000751
Genes in the cancer module 471 (more detail) 10 NA Homo sapiens
WIG001114
Genes involved in Purine catabolism (more detail) 10 NA Homo sapiens
MOX003796
Genes associated with Computational Drug Signature carbofuran Genes associated with Computational Drug Signature carbofuran, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens
MOX001445
Genes associated with Computational Drug Signature 1 aminobenzotriazole Genes associated with Computational Drug Signature 1-aminobenzotriazole, curated by the Drug Signatu (more detail) 10 25990557 Homo sapiens
MOX001513
Genes associated with Computational Drug Signature Anthraflavic acid Genes associated with Computational Drug Signature Anthraflavic acid, curated by the Drug Signature (more detail) 10 25990557 Homo sapiens
MOX007586
Genes associated with Computational Drug Signature CGS 12066B Genes associated with Computational Drug Signature CGS-12066B, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens
TAX019280
GO:0016884 molecular function carbon nitrogen ligase activity, with glutamine as amido N donor Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases cat (more detail) 10 NA Homo sapiens
TAX025403
GO:0046033 biological process AMP metabolic process The chemical reactions and pathways involving AMP, adenosine monophosphate. (more detail) 10 NA Homo sapiens
TAX025932
GO:0047429 molecular function nucleoside triphosphate diphosphatase activity Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide. (more detail) 10 NA Homo sapiens
TAX031753
GO:0150077 biological process regulation of neuroinflammatory response Any process that modulates the frequency, rate or extent of neuroinflammatory response. (more detail) 10 NA Homo sapiens
TAX000002
Genes annotated by the GO term GO:0030048. Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. (more detail) 10 NA Homo sapiens
FOX000542
Genes in the cancer module 21 (more detail) 10 NA Homo sapiens
TAX001291
Genes annotated by the GO term GO:0016706. Catalysis of an oxidation reduction (redox) reaction in which hydrogen or electrons are transferred from 2 oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor. (more detail) 10 NA Homo sapiens
TAX000574
Genes annotated by the GO term GO:0006163. The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5' hydroxyl group of its glycose moiety. (more detail) 10 NA Homo sapiens
TAX018787
GO:0015924 molecular function mannosyl oligosaccharide mannosidase activity Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharid (more detail) 10 NA Homo sapiens
MOX017941
Genes associated with Computational Drug Signature Afatinib Genes associated with Computational Drug Signature Afatinib, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
MOX013102
Genes associated with Computational Drug Signature IK 682 Genes associated with Computational Drug Signature IK-682, curated by the Drug Signature Database (D (more detail) 10 25990557 Homo sapiens
TAX016436
GO:0006569 biological process tryptophan catabolic process The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid (more detail) 10 NA Homo sapiens
TAX016834
GO:0007195 biological process adenylate cyclase inhibiting dopamine receptor signaling pathway The series of molecular signals generated as a consequence of a dopamine receptor binding to its phy (more detail) 10 NA Homo sapiens
TAX033238
GO:1903978 biological process regulation of microglial cell activation Any process that modulates the frequency, rate or extent of microglial cell activation. (more detail) 10 NA Homo sapiens
WIG001142
Genes involved in Regulation of Insulin Secretion by Acetylcholine (more detail) 10 NA Homo sapiens
MOX005033
Genes associated with Computational Drug Signature Quinpirole dihydrochloride Genes associated with Computational Drug Signature Quinpirole dihydrochloride, curated by the Drug S (more detail) 10 25990557 Homo sapiens
TAX019179
GO:0016723 molecular function oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and NAD+ or (more detail) 10 NA Homo sapiens
TAX020939
GO:0031340 biological process positive regulation of vesicle fusion Any process that activates or increases the frequency, rate or extent of vesicle fusion. (more detail) 10 NA Homo sapiens
MOX012247
Genes associated with Computational Drug Signature dexamethasone Genes associated with Computational Drug Signature dexamethasone, curated by the Drug Signature Data (more detail) 10 25990557 Homo sapiens
WIG000313
Eph Kinases and ephrins support platelet aggregation Eph kinases are a family of receptor tyrosine kinases with an extracellular domain that binds their (more detail) 10 NA Homo sapiens
MAX002889
Protein kinase genes most significantly up regulated in ASPS (alveolar soft part sarcoma) tumors compared to four other types of primitive sarcomas. Specific chromosomal translocations encoding chimeric transcription factors are considered to play c (more detail) 10 NA Homo sapiens
MOX001741
Genes associated with Computational Drug Signature DIISODECYL PHTHALATE Genes associated with Computational Drug Signature DIISODECYL PHTHALATE, curated by the Drug Signatu (more detail) 10 25990557 Homo sapiens
MOX013460
Genes associated with Computational Drug Signature Linifanib Genes associated with Computational Drug Signature Linifanib, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
TAX016437
GO:0006570 biological process tyrosine metabolic process The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxy (more detail) 10 NA Homo sapiens
TAX019038
GO:0016461 cellular component unconventional myosin complex A portmanteau term for myosins other than myosin II. (more detail) 10 NA Homo sapiens
TAX025496
GO:0046218 biological process indolalkylamine catabolic process The chemical reactions and pathways resulting in the breakdown of indolalkylamines, indole or indole (more detail) 10 NA Homo sapiens
MOX017651
Genes associated with Computational Drug Signature Regorafenib Genes associated with Computational Drug Signature Regorafenib, curated by the Drug Signature Databa (more detail) 10 25990557 Homo sapiens
MOX016606
Genes associated with Computational Drug Signature deferiprone Genes associated with Computational Drug Signature deferiprone, curated by the Drug Signature Databa (more detail) 10 25990557 Homo sapiens
TAX000776
Genes annotated by the GO term GO:0006801. The chemical reactions and pathways involving superoxide, the superoxide anion O2 (superoxide free radical), or any compound containing this species. (more detail) 10 NA Homo sapiens
MEX000741
Genes associated with Approved Drug fulvestrant Genes associated with Approved Drug fulvestrant, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
TAX025548
GO:0046385 biological process deoxyribose phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phospho (more detail) 10 NA Homo sapiens
MOX014549
Genes associated with Computational Drug Signature piroxicam Genes associated with Computational Drug Signature piroxicam, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
MEX001186
Genes associated with Approved Drug piroxicam Genes associated with Approved Drug piroxicam, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MOX001178
Genes associated with Computational Drug Signature DIHEXYL PHTHALATE Genes associated with Computational Drug Signature DIHEXYL PHTHALATE, curated by the Drug Signature (more detail) 10 25990557 Homo sapiens
MOX003048
Genes associated with Computational Drug Signature Pitavastatin calcium Genes associated with Computational Drug Signature Pitavastatin calcium, curated by the Drug Signatu (more detail) 10 25990557 Homo sapiens
MOX002396
Genes associated with Computational Drug Signature Tolcapone Genes associated with Computational Drug Signature Tolcapone, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
WIG001122
Genes involved in RAF/MAP kinase cascade (more detail) 10 NA Homo sapiens
TAX034131
GO:1990001 biological process inhibition of cysteine type endopeptidase activity involved in apoptotic process Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an a (more detail) 10 NA Homo sapiens
TAX023713
GO:0042178 biological process xenobiotic catabolic process The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound (more detail) 10 NA Homo sapiens
TAX023838
GO:0042436 biological process indole containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole ( (more detail) 10 NA Homo sapiens
IEI010519
Protein protein interactors of human gene PROC from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PROC (SwissProt ID=P (more detail) 14 17535438 Homo sapiens
IEI005727
Protein protein interactors of human gene HBEGF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HBEGF (SwissProt ID= (more detail) 14 17535438 Homo sapiens
MOX016310
Genes associated with Computational Drug Signature phenylbutazone Genes associated with Computational Drug Signature phenylbutazone, curated by the Drug Signature Dat (more detail) 14 25990557 Homo sapiens
WIG000179
Ras signaling in the CD4+ TCR pathway (more detail) 14 NA Homo sapiens
MOX004706
Genes associated with Computational Drug Signature sulpiride Genes associated with Computational Drug Signature sulpiride, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens
TAX017511
GO:0009109 biological process coenzyme catabolic process The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprote (more detail) 14 NA Homo sapiens
MOX016942
Genes associated with Computational Drug Signature flurbiprofen Genes associated with Computational Drug Signature flurbiprofen, curated by the Drug Signature Datab (more detail) 14 25990557 Homo sapiens
TAX023792
GO:0042359 biological process vitamin D metabolic process The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble comp (more detail) 14 NA Homo sapiens
WIG001322
Atorvastatin/Lovastatin/Simvastatin Pathway, Pharmacokinetics Drug-specific representation of the candidate genes involved in transport, metabolism and clearance. (more detail) 14 NA Homo sapiens
TAX034813
GO:2000615 biological process regulation of histone H3 K9 acetylation Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation. (more detail) 14 NA Homo sapiens
MOX014037
Genes associated with Computational Drug Signature nimesulide Genes associated with Computational Drug Signature nimesulide, curated by the Drug Signature Databas (more detail) 14 25990557 Homo sapiens
WIG001041
Genes involved in N Glycan antennae elongation (more detail) 14 NA Homo sapiens
TAX000931
Genes annotated by the GO term GO:0005871. Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work. (more detail) 14 NA Homo sapiens
TAX024043
GO:0042834 molecular function peptidoglycan binding Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a c (more detail) 14 NA Homo sapiens
FEX001923
Lung Magda08 21genes Table 1a. Transcriptional responses in A549 cultures treated with zinc ionophores (more detail) 14 18593933 Homo sapiens
WIG001494
Extrinsic Prothrombin Activation Pathway Extrinsic Prothrombin Activation Pathway (more detail) 14 NA Homo sapiens
MEX000971
Genes associated with Approved Drug acitretin Genes associated with Approved Drug acitretin, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
TAX017528
GO:0009130 biological process pyrimidine nucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphat (more detail) 14 NA Homo sapiens
MOX014988
Genes associated with Computational Drug Signature SB 206553 Genes associated with Computational Drug Signature SB 206553, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens
MOX017994
Genes associated with Computational Drug Signature SERTINDOLE Genes associated with Computational Drug Signature SERTINDOLE, curated by the Drug Signature Databas (more detail) 14 25990557 Homo sapiens
MOX017850
Genes associated with Computational Drug Signature thymine Genes associated with Computational Drug Signature thymine, curated by the Drug Signature Database ( (more detail) 14 25990557 Homo sapiens
FEX003322
Thyroid Arora09 21genes Table 1. Sixty-One Genes Differentially Expressed Between Benign Borderline and/or Malignant Thyro (more detail) 14 19658182 Homo sapiens
WIG000677
Genes involved in Acyl chain remodelling of PS (more detail) 14 NA Homo sapiens
WIG001327
Warfarin Pathway, Pharmacodynamics Simplified diagram of the target of warfarin action and downstream genes and effects. (more detail) 14 NA Homo sapiens
MEX000511
Genes associated with Approved Drug cladribine Genes associated with Approved Drug cladribine, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MOX004084
Genes associated with Computational Drug Signature 4602 84 0 Genes associated with Computational Drug Signature 4602-84-0, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens
MOX003817
Genes associated with Computational Drug Signature cephalothin Genes associated with Computational Drug Signature cephalothin, curated by the Drug Signature Databa (more detail) 14 25990557 Homo sapiens
MOX000540
Genes associated with Computational Drug Signature zaprinast Genes associated with Computational Drug Signature zaprinast, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens
MOX000004
Genes associated with Computational Drug Signature alachlor Genes associated with Computational Drug Signature alachlor, curated by the Drug Signature Database (more detail) 14 25990557 Homo sapiens
MOX013208
Genes associated with Computational Drug Signature Isoquercitrin Genes associated with Computational Drug Signature Isoquercitrin, curated by the Drug Signature Data (more detail) 14 25990557 Homo sapiens
TAX022382
GO:0034236 molecular function protein kinase A catalytic subunit binding Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kin (more detail) 14 NA Homo sapiens
IEI000632
Protein protein interactors of human gene ANKS1B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANKS1B (SwissProt ID (more detail) 12 17535438 Homo sapiens
IEI011402
Protein protein interactors of human gene RNF150 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF150 (SwissProt ID (more detail) 12 17535438 Homo sapiens
IEI015328
Protein protein interactors of human gene ZFYVE16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZFYVE16 (SwissProt I (more detail) 12 17535438 Homo sapiens
TAX028448
GO:0061478 biological process response to platelet aggregation inhibitor Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 12 NA Homo sapiens
TAX029448
GO:0071415 biological process cellular response to purine containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 12 NA Homo sapiens
IEI012174
Protein protein interactors of human gene SHC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SHC2 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens
IEI014170
Protein protein interactors of human gene TRAF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRAF7 (SwissProt ID= (more detail) 12 17535438 Homo sapiens
MOX013014
Genes associated with Computational Drug Signature Hexylene glycol Genes associated with Computational Drug Signature Hexylene glycol, curated by the Drug Signature Da (more detail) 12 25990557 Homo sapiens
TAX027590
GO:0055119 biological process relaxation of cardiac muscle The process in which the extent of cardiac muscle contraction is reduced. (more detail) 12 NA Homo sapiens
WAG000450
S1P1 pathway (more detail) 12 NA Homo sapiens
FEX001677
Leukemia Cleaver10 12genes Table S3b. GSEA leading edges from Wnt/Ca2+/cGMP pathway (more detail) 12 20459861 Homo sapiens
GEX001644
venous thrombosis venous thrombosis associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 12 NA Homo sapiens
TAX000075
Genes annotated by the GO term GO:0032488. A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP bound active state. (more detail) 12 NA Homo sapiens
WIG000903
Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (more detail) 12 NA Homo sapiens
MEX000753
Genes associated with Approved Drug clofarabine Genes associated with Approved Drug clofarabine, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX000432
Genes associated with Approved Drug 4 benzyloxyphenol Genes associated with Approved Drug 4-benzyloxyphenol, curated by the Drug Signature Database (DSigD (more detail) 12 25990557 Homo sapiens
MOX002005
Genes associated with Computational Drug Signature metolachlor Genes associated with Computational Drug Signature metolachlor, curated by the Drug Signature Databa (more detail) 12 25990557 Homo sapiens
MEX000537
Genes associated with Approved Drug bromocriptine mesylate Genes associated with Approved Drug bromocriptine mesylate, curated by the Drug Signature Database ( (more detail) 12 25990557 Homo sapiens
MOX000494
Genes associated with Computational Drug Signature Norharman Genes associated with Computational Drug Signature Norharman, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens
MOX005527
Genes associated with Computational Drug Signature 180083 23 2 Genes associated with Computational Drug Signature 180083-23-2, curated by the Drug Signature Databa (more detail) 12 25990557 Homo sapiens
TAX022445
GO:0034370 biological process triglyceride rich lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein p (more detail) 12 NA Homo sapiens
TAX016167
GO:0006171 biological process cAMP biosynthetic process The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, a (more detail) 12 NA Homo sapiens
WIG000252
AKAP95 role in mitosis and chromosome dynamics The chromatin packaging of the genome is dynamic, changing with the cell cycle and with transcriptio (more detail) 12 NA Homo sapiens
MOX013677
Genes associated with Computational Drug Signature methylergonovine Genes associated with Computational Drug Signature methylergonovine, curated by the Drug Signature D (more detail) 12 25990557 Homo sapiens
TAX020748
GO:0030983 molecular function mismatched DNA binding Interacting selectively and non-covalently with double-stranded DNA containing one or more mismatche (more detail) 12 NA Homo sapiens
MOX016489
Genes associated with Computational Drug Signature cccp Genes associated with Computational Drug Signature cccp, curated by the Drug Signature Database (DSi (more detail) 12 25990557 Homo sapiens
MOX017808
Genes associated with Computational Drug Signature 2,6 Di tert butyl 4 methylphenol Genes associated with Computational Drug Signature 2,6-Di-tert-butyl-4-methylphenol, curated by the (more detail) 12 25990557 Homo sapiens
TAX023824
GO:0042415 biological process norepinephrine metabolic process The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medu (more detail) 12 NA Homo sapiens
MEX000611
Genes associated with Approved Drug nefazodone hydrochloride Genes associated with Approved Drug nefazodone hydrochloride, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens
MOX002238
Genes associated with Computational Drug Signature 2',4' Dihydroxychalcone Genes associated with Computational Drug Signature 2',4'-Dihydroxychalcone, curated by the Drug Sign (more detail) 12 25990557 Homo sapiens
TAX018591
GO:0015368 molecular function calcium:cation antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to th (more detail) 12 NA Homo sapiens
WIG000406
Phospholipase C epsilon pathway Proposed model for b2-AR- and prostanoid-receptor-mediated PLC and calcium signalling. Receptors cou (more detail) 12 NA Homo sapiens
WIG001125
Genes involved in Receptor ligand binding initiates the second proteolytic cleavage of Notch receptor (more detail) 12 NA Homo sapiens
MOX004772
Genes associated with Computational Drug Signature tolbutamide Genes associated with Computational Drug Signature tolbutamide, curated by the Drug Signature Databa (more detail) 12 25990557 Homo sapiens
MOX005179
Genes associated with Computational Drug Signature ( ) Epicatechin Genes associated with Computational Drug Signature (-)-Epicatechin, curated by the Drug Signature Da (more detail) 12 25990557 Homo sapiens
TAX025469
GO:0046133 biological process pyrimidine ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside i (more detail) 12 NA Homo sapiens
TAX015503
GO:0004952 molecular function dopamine neurotransmitter receptor activity Combining with the neurotransmitter dopamine to initiate a change in cell activity. (more detail) 12 NA Homo sapiens
MOX004350
Genes associated with Computational Drug Signature methylergonovine Genes associated with Computational Drug Signature methylergonovine, curated by the Drug Signature D (more detail) 12 25990557 Homo sapiens
MOX004165
Genes associated with Computational Drug Signature cyclic gmp Genes associated with Computational Drug Signature cyclic gmp, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens
MOX003937
Genes associated with Computational Drug Signature beta Heparin Genes associated with Computational Drug Signature beta-Heparin, curated by the Drug Signature Datab (more detail) 12 25990557 Homo sapiens
MOX000332
Genes associated with Computational Drug Signature Triphenyltin hydroxide Genes associated with Computational Drug Signature Triphenyltin hydroxide, curated by the Drug Signa (more detail) 12 25990557 Homo sapiens
MOX013630
Genes associated with Computational Drug Signature mestranol Genes associated with Computational Drug Signature mestranol, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens
PEX001225
NUDIX: NUDIX domain (more detail) 12 NA Homo sapiens
MOX015159
Genes associated with Computational Drug Signature spermine Genes associated with Computational Drug Signature spermine, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens
MOX014927
Genes associated with Computational Drug Signature S (+) Rolipram Genes associated with Computational Drug Signature S-(+)-Rolipram, curated by the Drug Signature Dat (more detail) 12 25990557 Homo sapiens
FEX002443
Ovarian Bonome05 13genes Table 2B. Pathway genes unique to LMP ovarian tumors that inhibit tumor progression and metastasis ( (more detail) 12 16288054 Homo sapiens
FEX002748
Skin VanGele04 12genes Table 3a List of MCC and SCLC classifier genes (MCC specific genes) (more detail) 12 14755241 Homo sapiens
TAX001232
Genes annotated by the GO term GO:0001727. Catalysis of the phosphorylation of a simple or complex lipid. (more detail) 12 NA Homo sapiens
MEX000218
Genes associated with Approved Drug metolazone Genes associated with Approved Drug metolazone, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
TAX017523
GO:0009125 biological process nucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a comp (more detail) 12 NA Homo sapiens
TAX033635
GO:1904816 biological process positive regulation of protein localization to chromosome, telomeric region Any process that activates or increases the frequency, rate or extent of protein localization to chr (more detail) 12 NA Homo sapiens
MOX005346
Genes associated with Computational Drug Signature 1 (1 Naphthyl)piperazine Genes associated with Computational Drug Signature 1-(1-Naphthyl)piperazine, curated by the Drug Sig (more detail) 12 25990557 Homo sapiens
MOX000341
Genes associated with Computational Drug Signature flunisolide Genes associated with Computational Drug Signature flunisolide, curated by the Drug Signature Databa (more detail) 12 25990557 Homo sapiens
MOX000823
Genes associated with Computational Drug Signature Enilconazole Genes associated with Computational Drug Signature Enilconazole, curated by the Drug Signature Datab (more detail) 12 25990557 Homo sapiens
MOX001010
Genes associated with Computational Drug Signature ANILINE Genes associated with Computational Drug Signature ANILINE, curated by the Drug Signature Database ( (more detail) 12 25990557 Homo sapiens
MOX001594
Genes associated with Computational Drug Signature CYHALOTHRIN Genes associated with Computational Drug Signature CYHALOTHRIN, curated by the Drug Signature Databa (more detail) 12 25990557 Homo sapiens
WIG001188
Genes involved in Serotonin receptors (more detail) 12 NA Homo sapiens
TAX001062
Genes annotated by the GO term GO:0008376. Catalysis of the transfer of an N acetylgalactosaminyl residue from UDP N acetyl galactosamine to an oligosaccharide. (more detail) 12 NA Homo sapiens
TAX001448
Genes annotated by the GO term GO:0019842. Interacting selectively with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. (more detail) 12 NA Homo sapiens
TAX028903
GO:0070383 biological process DNA cytosine deamination The removal of an amino group from a cytosine residue in DNA, forming a uracil residue. (more detail) 7 NA Homo sapiens
IEI009782
Protein protein interactors of human gene PFKFB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PFKFB1 (SwissProt ID (more detail) 7 17535438 Homo sapiens
TAX024180
GO:0043140 molecular function ATP dependent 3' 5' DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the (more detail) 7 NA Homo sapiens
IEI010453
Protein protein interactors of human gene PRELP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PRELP (SwissProt ID= (more detail) 7 17535438 Homo sapiens
TAX024212
GO:0043190 cellular component ATP binding cassette (ABC) transporter complex A complex for the transport of metabolites into and out of the cell, typically comprised of four dom (more detail) 7 NA Homo sapiens
TAX022755
GO:0035184 molecular function histone threonine kinase activity Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any (more detail) 7 NA Homo sapiens
TAX022845
GO:0035374 molecular function chondroitin sulfate binding Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of (more detail) 7 NA Homo sapiens
TAX016869
GO:0007256 biological process activation of JNKK activity The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are i (more detail) 7 NA Homo sapiens
TAX030546
GO:0090494 biological process dopamine uptake The directed movement of dopamine into a cell. (more detail) 7 NA Homo sapiens
TAX031754
GO:0150078 biological process positive regulation of neuroinflammatory response Any process that activates or increases the frequency, rate or extent of neuroinflammatory response. (more detail) 7 NA Homo sapiens
TAX032246
GO:1901725 biological process regulation of histone deacetylase activity Any process that modulates the frequency, rate or extent of histone deacetylase activity. (more detail) 7 NA Homo sapiens
PEX000006
ABC tran: ABC transporter ABC transporters for a large family of proteins responsible for translocation of a variety of compou (more detail) 7 NA Homo sapiens
MOX014751
Genes associated with Computational Drug Signature Racemetirosine Genes associated with Computational Drug Signature Racemetirosine, curated by the Drug Signature Dat (more detail) 7 25990557 Homo sapiens
MOX014577
Genes associated with Computational Drug Signature PONATINIB Genes associated with Computational Drug Signature PONATINIB, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens
WIG001415
Cyclophosphamide Pathway, Pharmacokinetics Model human liver cell showing genes involved in the metabolism of cyclophosphamide. (more detail) 7 NA Homo sapiens
MEX001916
Genes associated with Kinase Inhibitor (E) N Methyl 2 ((3 (2 (pyridin 2 yl)vinyl) 1H indazol 6 yl)thio)benzamide Genes associated with Kinase Inhibitor (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)th (more detail) 7 25990557 Homo sapiens
MEX001614
Genes associated with Kinase Inhibitor Kinome 245 Genes associated with Kinase Inhibitor Kinome_245, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001693
Genes associated with Kinase Inhibitor Kinome 421 Genes associated with Kinase Inhibitor Kinome_421, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX001172
Genes associated with Computational Drug Signature naringenin chalcone Genes associated with Computational Drug Signature naringenin chalcone, curated by the Drug Signatur (more detail) 7 25990557 Homo sapiens
MOX006665
Genes associated with Computational Drug Signature AGN PC 001QKA Genes associated with Computational Drug Signature AGN-PC-001QKA, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens
MOX005106
Genes associated with Computational Drug Signature Delavirdine Genes associated with Computational Drug Signature Delavirdine, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX005257
Genes associated with Computational Drug Signature (R) ( ) Rolipram Genes associated with Computational Drug Signature (R)-(-)-Rolipram, curated by the Drug Signature D (more detail) 7 25990557 Homo sapiens
MOX011447
Genes associated with Computational Drug Signature CHEMBL575896 Genes associated with Computational Drug Signature CHEMBL575896, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
MOX013239
Genes associated with Computational Drug Signature JNJ 10198409 Genes associated with Computational Drug Signature JNJ-10198409, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
MOX012707
Genes associated with Computational Drug Signature fluconazole Genes associated with Computational Drug Signature fluconazole, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX014469
Genes associated with Computational Drug Signature Phenol, 4,4' (3 methyl 1 butenylidene)bis Genes associated with Computational Drug Signature Phenol, 4,4'-(3-methyl-1-butenylidene)bis-, curat (more detail) 7 25990557 Homo sapiens
FEX002728
Sarcoma Baird05 12genes Table 2. Tyrosine kinases and receptor tyrosine kinases associated with individual tumor groups (sho (more detail) 7 16230383 Homo sapiens
MAX001885
Nuclear receptors whose expression correlated with that of aromatase (CYP19A1) [GeneID=1588] in a panel of breast cancer biopsies. Aromatase is a key enzyme in intratumoral estrogen production required for the production of estroge (more detail) 7 NA Homo sapiens
MEX001399
Genes associated with Kinase Inhibitor MLS002232309 Genes associated with Kinase Inhibitor MLS002232309, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens
MEX001245
Genes associated with Kinase Inhibitor Kinome 131 Genes associated with Kinase Inhibitor Kinome_131, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX000589
Genes associated with Approved Drug atracurium besylate Genes associated with Approved Drug atracurium besylate, curated by the Drug Signature Database (DSi (more detail) 7 25990557 Homo sapiens
MEX001754
Genes associated with Kinase Inhibitor Kinome 471 Genes associated with Kinase Inhibitor Kinome_471, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX000632
Genes associated with Computational Drug Signature N Nitrosodipropylamine Genes associated with Computational Drug Signature N-Nitrosodipropylamine, curated by the Drug Signa (more detail) 7 25990557 Homo sapiens
MOX006535
Genes associated with Computational Drug Signature AC1L27WO Genes associated with Computational Drug Signature AC1L27WO, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens
MOX005340
Genes associated with Computational Drug Signature 1,5 Diaminopentane Genes associated with Computational Drug Signature 1,5-Diaminopentane, curated by the Drug Signature (more detail) 7 25990557 Homo sapiens
MOX004454
Genes associated with Computational Drug Signature oxazepam Genes associated with Computational Drug Signature oxazepam, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens
MOX006363
Genes associated with Computational Drug Signature 722544 51 6 Genes associated with Computational Drug Signature 722544-51-6, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX011982
Genes associated with Computational Drug Signature Cipemastat Genes associated with Computational Drug Signature Cipemastat, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
MOX011430
Genes associated with Computational Drug Signature CHEMBL574589 Genes associated with Computational Drug Signature CHEMBL574589, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
TAX021417
GO:0032261 biological process purine nucleotide salvage Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis. (more detail) 7 NA Homo sapiens
TAX022992
GO:0035627 biological process ceramide transport The directed movement of ceramides into, out of or within a cell, or between cells, by means of some (more detail) 7 NA Homo sapiens
TAX022861
GO:0035405 biological process histone threonine phosphorylation The modification of histones by addition of a phosphate group to a threonine residue. (more detail) 7 NA Homo sapiens
TAX030545
GO:0090493 biological process catecholamine uptake The directed movement of catecholamine into a cell. (more detail) 7 NA Homo sapiens
TAX017779
GO:0009820 biological process alkaloid metabolic process The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which (more detail) 7 NA Homo sapiens
TAX019078
GO:0016530 molecular function metallochaperone activity Assists in the delivery of metal ions to target proteins or compartments. (more detail) 7 NA Homo sapiens
TAX033240
GO:1903980 biological process positive regulation of microglial cell activation Any process that activates or increases the frequency, rate or extent of microglial cell activation. (more detail) 7 NA Homo sapiens
TAX015322
GO:0004691 molecular function cAMP dependent protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the pres (more detail) 7 NA Homo sapiens
TAX015345
GO:0004723 molecular function calcium dependent protein serine/threonine phosphatase activity Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein (more detail) 7 NA Homo sapiens
MOX011750
Genes associated with Computational Drug Signature CHEMBL76100 Genes associated with Computational Drug Signature CHEMBL76100, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX012200
Genes associated with Computational Drug Signature Decyl Sulfamate Genes associated with Computational Drug Signature Decyl Sulfamate, curated by the Drug Signature Da (more detail) 7 25990557 Homo sapiens
MOX012531
Genes associated with Computational Drug Signature ENOXIMONE Genes associated with Computational Drug Signature ENOXIMONE, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens
MOX014316
Genes associated with Computational Drug Signature p coumaric acid Genes associated with Computational Drug Signature p-coumaric acid, curated by the Drug Signature Da (more detail) 7 25990557 Homo sapiens
MEX000052
Genes associated with Approved Drug busulfan Genes associated with Approved Drug busulfan, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001611
Genes associated with Kinase Inhibitor Kinome 125 Genes associated with Kinase Inhibitor Kinome_125, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001494
Genes associated with Kinase Inhibitor EGFR/ErbB 2/ErbB 4 Inhibitor Genes associated with Kinase Inhibitor EGFR/ErbB-2/ErbB-4 Inhibitor, curated by the Drug Signature D (more detail) 7 25990557 Homo sapiens
MOX000978
Genes associated with Computational Drug Signature CHLORIC ACID Genes associated with Computational Drug Signature CHLORIC ACID, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
MOX000101
Genes associated with Computational Drug Signature 3 Oxoestr 4 en 17 yl decanoate Genes associated with Computational Drug Signature 3-Oxoestr-4-en-17-yl decanoate, curated by the Dr (more detail) 7 25990557 Homo sapiens
MOX003088
Genes associated with Computational Drug Signature Ranirestat Genes associated with Computational Drug Signature Ranirestat, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
TAX022682
GO:0034983 biological process peptidyl lysine deacetylation The removal of an acetyl group from an acetylated lysine residue in a peptide or protein. (more detail) 7 NA Homo sapiens
TAX023332
GO:0036310 molecular function annealing helicase activity Catalysis of the ATP-dependent rewinding of single-stranded DNA (ssDNA) to reform base pairs between (more detail) 7 NA Homo sapiens
TAX017745
GO:0009698 biological process phenylpropanoid metabolic process The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid. (more detail) 7 NA Homo sapiens
TAX019329
GO:0017002 molecular function activin activated receptor activity Combining with activin and transmitting the signal from one side of the membrane to the other to ini (more detail) 7 NA Homo sapiens
TAX019505
GO:0018243 biological process protein O linked glycosylation via threonine The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; (more detail) 7 NA Homo sapiens
TAX018969
GO:0016308 molecular function 1 phosphatidylinositol 4 phosphate 5 kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo- (more detail) 7 NA Homo sapiens
PEX000267
BIR: Inhibitor of Apoptosis domain BIR stands for Baculovirus Inhibitor of apoptosis protein Repeat. It is found repeated in inhibitor (more detail) 7 NA Homo sapiens
MOX011743
Genes associated with Computational Drug Signature CHEMBL74983 Genes associated with Computational Drug Signature CHEMBL74983, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX015778
Genes associated with Computational Drug Signature UNII ZZ6VH5MZ17 Genes associated with Computational Drug Signature UNII-ZZ6VH5MZ17, curated by the Drug Signature Da (more detail) 7 25990557 Homo sapiens
WAG000119
Synthesis of DNA (more detail) 7 NA Homo sapiens
MEX001607
Genes associated with Kinase Inhibitor Kinome 41 Genes associated with Kinase Inhibitor Kinome_41, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001619
Genes associated with Kinase Inhibitor GW410563A Genes associated with Kinase Inhibitor GW410563A, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002330
Genes associated with Kinase Inhibitor Kinome 423 Genes associated with Kinase Inhibitor Kinome_423, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002065
Genes associated with Kinase Inhibitor Kinome 1078 Genes associated with Kinase Inhibitor Kinome_1078, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001824
Genes associated with Kinase Inhibitor Kinome 575 Genes associated with Kinase Inhibitor Kinome_575, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX006666
Genes associated with Computational Drug Signature AGN PC 001QKE Genes associated with Computational Drug Signature AGN-PC-001QKE, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens
MOX005843
Genes associated with Computational Drug Signature 3 (4 Hydroxy phenyl) 2,3 diphenyl acrylonitrile Genes associated with Computational Drug Signature 3-(4-Hydroxy-phenyl)-2,3-diphenyl-acrylonitrile, (more detail) 7 25990557 Homo sapiens
MOX003142
Genes associated with Computational Drug Signature Emtricitabine Genes associated with Computational Drug Signature Emtricitabine, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens
MOX002873
Genes associated with Computational Drug Signature Benfuracarb Genes associated with Computational Drug Signature Benfuracarb, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX007218
Genes associated with Computational Drug Signature BENZOLAMIDE Genes associated with Computational Drug Signature BENZOLAMIDE, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX009490
Genes associated with Computational Drug Signature CHEMBL294120 Genes associated with Computational Drug Signature CHEMBL294120, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
MOX013193
Genes associated with Computational Drug Signature isogranulatimide Genes associated with Computational Drug Signature isogranulatimide, curated by the Drug Signature D (more detail) 7 25990557 Homo sapiens
TAX022691
GO:0035005 molecular function 1 phosphatidylinositol 4 phosphate 3 kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo- (more detail) 7 NA Homo sapiens
TAX017348
GO:0008559 molecular function xenobiotic transmembrane transporting ATPase activity Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out). (more detail) 7 NA Homo sapiens
TAX022563
GO:0034618 molecular function arginine binding Interacting selectively and non-covalently with 2-amino-5-(carbamimidamido)pentanoic acid. (more detail) 7 NA Homo sapiens
TAX030521
GO:0090382 biological process phagosome maturation A process that is carried out at the cellular level which results in the arrangement of constituent (more detail) 7 NA Homo sapiens
TAX021593
GO:0032489 biological process regulation of Cdc42 protein signal transduction Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction. (more detail) 7 NA Homo sapiens
TAX015488
GO:0004931 molecular function extracellularly ATP gated cation channel activity Enables the transmembrane transfer of a cation by a channel that opens when ATP is bound by the chan (more detail) 7 NA Homo sapiens
TAX015545
GO:0005004 molecular function GPI linked ephrin receptor activity Combining with a GPI-anchored ephrin to initiate a change in cell activity. (more detail) 7 NA Homo sapiens
TAX015329
GO:0004703 molecular function G protein coupled receptor kinase activity Catalysis of the reaction: ATP + G-protein coupled receptor = ADP + G-protein coupled receptor phosp (more detail) 7 NA Homo sapiens
PEX000297
EGF CA: Calcium binding EGF domain (more detail) 7 NA Homo sapiens
PEX002283
EF hand 5: EF hand (more detail) 7 NA Homo sapiens
MOX014637
Genes associated with Computational Drug Signature Prostratin Genes associated with Computational Drug Signature Prostratin, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
MEX001256
Genes associated with Kinase Inhibitor 1 [4 (4 amino 6 methylthieno[2,3 d]pyrimidin 5 yl)phenyl] 3 (3,5 dimethylphenyl)urea Genes associated with Kinase Inhibitor 1-[4-(4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl)phenyl]-3-( (more detail) 7 25990557 Homo sapiens
MEX001660
Genes associated with Kinase Inhibitor GW827099X Genes associated with Kinase Inhibitor GW827099X, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001608
Genes associated with Kinase Inhibitor Kinome 332 Genes associated with Kinase Inhibitor Kinome_332, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001637
Genes associated with Kinase Inhibitor MRT67307 Genes associated with Kinase Inhibitor MRT67307, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX001058
Genes associated with Computational Drug Signature Dimethyl phthalate Genes associated with Computational Drug Signature Dimethyl phthalate, curated by the Drug Signature (more detail) 7 25990557 Homo sapiens
MEX001808
Genes associated with Kinase Inhibitor TG003 Genes associated with Kinase Inhibitor TG003, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
TAX014770
GO:0003708 molecular function retinoic acid receptor activity Combining with retinoic acid and transmitting the signal to the transcriptional machinery by interac (more detail) 7 NA Homo sapiens
TAX015557
GO:0005021 molecular function vascular endothelial growth factor activated receptor activity Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the pl (more detail) 7 NA Homo sapiens
PEX000031
Peptidase M14: Zinc carboxypeptidase (more detail) 7 NA Homo sapiens
PEX000852
EF hand 8: EF hand domain pair (more detail) 7 NA Homo sapiens
PEX000859
Annexin: Annexin This family of annexins also includes giardin that has been shown to function as an annexin 1. (more detail) 7 NA Homo sapiens
MOX011736
Genes associated with Computational Drug Signature CHEMBL73495 Genes associated with Computational Drug Signature CHEMBL73495, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX012111
Genes associated with Computational Drug Signature Cyclofenil diphenol Genes associated with Computational Drug Signature Cyclofenil diphenol, curated by the Drug Signatur (more detail) 7 25990557 Homo sapiens
MOX016283
Genes associated with Computational Drug Signature Bivalirudin Genes associated with Computational Drug Signature Bivalirudin, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX014225
Genes associated with Computational Drug Signature Octyl Sulfamate Genes associated with Computational Drug Signature Octyl Sulfamate, curated by the Drug Signature Da (more detail) 7 25990557 Homo sapiens
TAX013232
GO:0000052 biological process citrulline metabolic process The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino a (more detail) 7 NA Homo sapiens
MEX001322
Genes associated with Kinase Inhibitor CHEMBL189231 Genes associated with Kinase Inhibitor CHEMBL189231, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens
MEX001540
Genes associated with Kinase Inhibitor GW300660X Genes associated with Kinase Inhibitor GW300660X, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002282
Genes associated with Kinase Inhibitor Akt inhibitor VIII Genes associated with Kinase Inhibitor Akt inhibitor VIII, curated by the Drug Signature Database (D (more detail) 7 25990557 Homo sapiens
MOX001925
Genes associated with Computational Drug Signature Germacrone Genes associated with Computational Drug Signature Germacrone, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
MEX001792
Genes associated with Kinase Inhibitor GSK994854A Genes associated with Kinase Inhibitor GSK994854A, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002185
Genes associated with Kinase Inhibitor Kinome 507 Genes associated with Kinase Inhibitor Kinome_507, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX000836
Genes associated with Approved Drug rocuronium bromide Genes associated with Approved Drug rocuronium bromide, curated by the Drug Signature Database (DSig (more detail) 7 25990557 Homo sapiens
MOX001516
Genes associated with Computational Drug Signature Rimcazole Genes associated with Computational Drug Signature Rimcazole, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens
MOX000584
Genes associated with Computational Drug Signature DIISONONYL PHTHALATE Genes associated with Computational Drug Signature DIISONONYL PHTHALATE, curated by the Drug Signatu (more detail) 7 25990557 Homo sapiens
MOX006051
Genes associated with Computational Drug Signature 4 cycloheptyliden(4 hydroxyphenyl)methylphenol Genes associated with Computational Drug Signature 4-cycloheptyliden(4-hydroxyphenyl)methylphenol, c (more detail) 7 25990557 Homo sapiens
TAX017272
GO:0008443 molecular function phosphofructokinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a phosphofructose substrate mol (more detail) 7 NA Homo sapiens
TAX023696
GO:0042148 biological process strand invasion The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the rec (more detail) 7 NA Homo sapiens
TAX017774
GO:0009804 biological process coumarin metabolic process The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic sk (more detail) 7 NA Homo sapiens
MOX015388
Genes associated with Computational Drug Signature SYRINGIC ACID Genes associated with Computational Drug Signature SYRINGIC ACID, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens
MOX014397
Genes associated with Computational Drug Signature PD173955 Genes associated with Computational Drug Signature PD173955, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens
MOX014459
Genes associated with Computational Drug Signature Phenelzine Genes associated with Computational Drug Signature Phenelzine, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
TAX023840
GO:0042439 biological process ethanolamine containing compound metabolic process The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived fr (more detail) 7 NA Homo sapiens
WAG001315
DNA Replication (more detail) 7 NA Homo sapiens
GEX000715
gallstones gallstones associated genes. PAGER constructed this gene set by grouping all genes which are associa (more detail) 7 NA Homo sapiens
MEX001379
Genes associated with Kinase Inhibitor Kinome 683 Genes associated with Kinase Inhibitor Kinome_683, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX000990
Genes associated with Approved Drug nateglinide Genes associated with Approved Drug nateglinide, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002258
Genes associated with Kinase Inhibitor GW795486X Genes associated with Kinase Inhibitor GW795486X, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002270
Genes associated with Kinase Inhibitor Tozasertib Genes associated with Kinase Inhibitor Tozasertib, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002271
Genes associated with Kinase Inhibitor Oxindole Based Inhibitor 80 Genes associated with Kinase Inhibitor Oxindole-Based Inhibitor 80, curated by the Drug Signature Da (more detail) 7 25990557 Homo sapiens
MEX002157
Genes associated with Kinase Inhibitor Kinome 2847 Genes associated with Kinase Inhibitor Kinome_2847, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001870
Genes associated with Kinase Inhibitor CHEMBL458415 Genes associated with Kinase Inhibitor CHEMBL458415, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens
MOX003102
Genes associated with Computational Drug Signature 5 Hydroxydiclofenac Genes associated with Computational Drug Signature 5-Hydroxydiclofenac, curated by the Drug Signatur (more detail) 7 25990557 Homo sapiens
MOX006664
Genes associated with Computational Drug Signature AGN PC 001QK8 Genes associated with Computational Drug Signature AGN-PC-001QK8, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens
MOX011418
Genes associated with Computational Drug Signature CHEMBL573935 Genes associated with Computational Drug Signature CHEMBL573935, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
TAX022729
GO:0035095 biological process behavioral response to nicotine Any process that results in a change in the behavior of an organism as a result of a nicotine stimul (more detail) 7 NA Homo sapiens
GEX168000
Alcohol dependence Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replic (more detail) 7 23456092 Homo sapiens
TAX015055
GO:0004321 molecular function fatty acyl CoA synthase activity Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain ac (more detail) 7 NA Homo sapiens
GEX000411
cholesterol cholesterol, hdl cholesterol, ldl lipoprotein triglycerides cholesterol cholesterol, hdl cholesterol, ldl lipoprotein triglycerides associated genes. PAGER cons (more detail) 7 NA Homo sapiens
GEX001563
tardive dyskinesia tardive dyskinesia associated genes. PAGER constructed this gene set by grouping all genes which are (more detail) 7 NA Homo sapiens
MEX000094
Genes associated with Approved Drug diazoxide Genes associated with Approved Drug diazoxide, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001877
Genes associated with Kinase Inhibitor CHEMBL508928 Genes associated with Kinase Inhibitor CHEMBL508928, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens
MEX002291
Genes associated with Kinase Inhibitor CHEMBL188268 Genes associated with Kinase Inhibitor CHEMBL188268, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens
MEX001845
Genes associated with Kinase Inhibitor Lapatinib Genes associated with Kinase Inhibitor Lapatinib, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX000150
Genes associated with Computational Drug Signature CYTISINE Genes associated with Computational Drug Signature CYTISINE, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens
MOX002769
Genes associated with Computational Drug Signature Tebuconazole Genes associated with Computational Drug Signature Tebuconazole, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
MOX011199
Genes associated with Computational Drug Signature CHEMBL538718 Genes associated with Computational Drug Signature CHEMBL538718, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
TAX022381
GO:0034235 molecular function GPI anchor binding Interacting selectively and non-covalently with any glycosylphosphatidylinositol anchor. GPI anchors (more detail) 7 NA Homo sapiens
TAX015373
GO:0004767 molecular function sphingomyelin phosphodiesterase activity Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+). (more detail) 7 NA Homo sapiens
TAX017364
GO:0008603 molecular function cAMP dependent protein kinase regulator activity Modulation of the activity of the enzyme cAMP-dependent protein kinase. (more detail) 7 NA Homo sapiens
WIG000275
Transcription Regulation by Methyltransferase of CARM1 Several forms of post-translational modification regulate protein activities. Recently, protein meth (more detail) 13 NA Homo sapiens
MOX001310
Genes associated with Computational Drug Signature lauric acid Genes associated with Computational Drug Signature lauric acid, curated by the Drug Signature Databa (more detail) 13 25990557 Homo sapiens
WIG001346
Taxane Pathway, Pharmacokinetics Representation of the genes involved in the metabolism and transport of paclitaxel and docetaxel, an (more detail) 13 NA Homo sapiens
MOX006679
Genes associated with Computational Drug Signature AGN PC 00BUNE Genes associated with Computational Drug Signature AGN-PC-00BUNE, curated by the Drug Signature Data (more detail) 13 25990557 Homo sapiens
TAX024005
GO:0042762 biological process regulation of sulfur metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 13 NA Homo sapiens
TAX000568
Genes annotated by the GO term GO:0051262. The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits. (more detail) 13 NA Homo sapiens
MEX000933
Genes associated with Approved Drug vitamin d3 Genes associated with Approved Drug vitamin d3, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
WIG001334
Platinum Pathway, Pharmacokinetics/Pharmacodynamics Representation of the candidate genes involved in the metabolism of platinum containing drugs. (more detail) 13 NA Homo sapiens
WIG000990
Genes involved in Mitochondrial Fatty Acid Beta Oxidation (more detail) 13 NA Homo sapiens
TAX000730
Genes annotated by the GO term GO:0009259. The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5' hydroxyl group of its glycose moiety. (more detail) 13 NA Homo sapiens
MOX012666
Genes associated with Computational Drug Signature fenofibrate Genes associated with Computational Drug Signature fenofibrate, curated by the Drug Signature Databa (more detail) 13 25990557 Homo sapiens
TAX016606
GO:0006809 biological process nitric oxide biosynthetic process The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (N (more detail) 13 NA Homo sapiens
MOX005546
Genes associated with Computational Drug Signature 1H Pyrrole 2,5 dione, 3,4 diphenyl Genes associated with Computational Drug Signature 1H-Pyrrole-2,5-dione, 3,4-diphenyl-, curated by t (more detail) 13 25990557 Homo sapiens
WIG001403
Irinotecan Pathway, Pharmacokinetics Model human liver cell showing blood, bile and intestinal compartments, indicating tissue specific i (more detail) 13 NA Homo sapiens
WIG000321
Extrinsic Prothrombin Activation Pathway Blood coagulation or clotting takes place in 3 essential phases. The first phase is the activation o (more detail) 13 NA Homo sapiens
TAX033633
GO:1904814 biological process regulation of protein localization to chromosome, telomeric region Any process that modulates the frequency, rate or extent of protein localization to chromosome, telo (more detail) 13 NA Homo sapiens
MOX012167
Genes associated with Computational Drug Signature danazol Genes associated with Computational Drug Signature danazol, curated by the Drug Signature Database ( (more detail) 13 25990557 Homo sapiens
MAX002986
Cluster 4: ECM related genes up regulated in dermal fibroblasts later than 30 min after TGFB1 [GeneID=7040] addition; kept increasing with time. Despite major advances in the understanding of the intimate mechanisms of transforming growth factor (more detail) 13 NA Homo sapiens
MOX014330
Genes associated with Computational Drug Signature paclitaxel Genes associated with Computational Drug Signature paclitaxel, curated by the Drug Signature Databas (more detail) 13 25990557 Homo sapiens
WIG000248
Attenuation of GPCR Signaling The G-protein coupled receptor (GPCR) family transduces extracellular signals across the plasma memb (more detail) 13 NA Homo sapiens
MEX000727
Genes associated with Approved Drug bexarotene Genes associated with Approved Drug bexarotene, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MEX001158
Genes associated with Approved Drug cephapirin sodium Genes associated with Approved Drug cephapirin sodium, curated by the Drug Signature Database (DSigD (more detail) 13 25990557 Homo sapiens
MOX000126
Genes associated with Computational Drug Signature 2 Phenylphenol Genes associated with Computational Drug Signature 2-Phenylphenol, curated by the Drug Signature Dat (more detail) 13 25990557 Homo sapiens
MOX006059
Genes associated with Computational Drug Signature 4 Hexylresorcinol Genes associated with Computational Drug Signature 4-Hexylresorcinol, curated by the Drug Signature (more detail) 13 25990557 Homo sapiens
TAX026119
GO:0048266 biological process behavioral response to pain Any process that results in a change in the behavior of an organism as a result of a pain stimulus. (more detail) 13 NA Homo sapiens
MOX005545
Genes associated with Computational Drug Signature 1H Pyrrole 2,5 dione, 3,4 bis(4 methoxyphenyl) Genes associated with Computational Drug Signature 1H-Pyrrole-2,5-dione, 3,4-bis(4-methoxyphenyl)-, (more detail) 13 25990557 Homo sapiens
TAX018193
GO:0010885 biological process regulation of cholesterol storage Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the acc (more detail) 13 NA Homo sapiens
TAX019450
GO:0018027 biological process peptidyl lysine dimethylation The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine. (more detail) 13 NA Homo sapiens
MOX016097
Genes associated with Computational Drug Signature tyramine Genes associated with Computational Drug Signature tyramine, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens
GEX000370
carotid atherosclerosis carotid atherosclerosis associated genes. PAGER constructed this gene set by grouping all genes whic (more detail) 13 NA Homo sapiens
WAG001278
Regulation of cytoplasmic and nuclear SMAD2/3 signaling (more detail) 13 NA Homo sapiens
WIG001927
Irinotecan Pathway Irinotecan Pathway (more detail) 13 NA Homo sapiens
GEX167322
D dimer levels Genetic predictors of fibrin D-dimer levels in healthy adults. (more detail) 13 21502573 Homo sapiens
TAX021044
GO:0031543 molecular function peptidyl proline dioxygenase activity Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + s (more detail) 13 NA Homo sapiens
MOX015935
Genes associated with Computational Drug Signature zaprinast Genes associated with Computational Drug Signature zaprinast, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens
FEX000014
Bladder Tsunoda05 13genes Table 2. The differential expression between KK47 and KK47/DDP20 (more detail) 13 15608674 Homo sapiens
MOX012731
Genes associated with Computational Drug Signature flutamide Genes associated with Computational Drug Signature flutamide, curated by the Drug Signature Database (more detail) 13 25990557 Homo sapiens
TAX015443
GO:0004859 molecular function phospholipase inhibitor activity Stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolys (more detail) 13 NA Homo sapiens
MOX014294
Genes associated with Computational Drug Signature oxiconazole Genes associated with Computational Drug Signature oxiconazole, curated by the Drug Signature Databa (more detail) 13 25990557 Homo sapiens
IEI008456
Protein protein interactors of human gene MYL9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MYL9 (SwissProt ID=P (more detail) 13 17535438 Homo sapiens
IEI011256
Protein protein interactors of human gene RGS4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RGS4 (SwissProt ID=P (more detail) 13 17535438 Homo sapiens
IEI008635
Protein protein interactors of human gene NCOA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NCOA4 (SwissProt ID= (more detail) 13 17535438 Homo sapiens
IEI009745
Protein protein interactors of human gene PELI3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PELI3 (SwissProt ID= (more detail) 13 17535438 Homo sapiens
TAX024199
GO:0043173 biological process nucleotide salvage Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified wi (more detail) 13 NA Homo sapiens
IEI014240
Protein protein interactors of human gene TRIM36 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM36 (SwissProt ID (more detail) 13 17535438 Homo sapiens
IEI011142
Protein protein interactors of human gene RCVRN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RCVRN (SwissProt ID= (more detail) 13 17535438 Homo sapiens
IEI000332
Protein protein interactors of human gene AFAP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene AFAP1 (SwissProt ID= (more detail) 13 17535438 Homo sapiens
IEI003982
Protein protein interactors of human gene EFNA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFNA5 (SwissProt ID= (more detail) 13 17535438 Homo sapiens
IEI014275
Protein protein interactors of human gene TRIM74 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM74 (SwissProt ID (more detail) 13 17535438 Homo sapiens
MOX001244
Genes associated with Computational Drug Signature ISOPROTURON Genes associated with Computational Drug Signature ISOPROTURON, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
MOX003014
Genes associated with Computational Drug Signature Sitaxentan Genes associated with Computational Drug Signature Sitaxentan, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens
TAX021413
GO:0032252 biological process secretory granule localization Any process in which a secretory granule is transported to, and/or maintained in, a specific locatio (more detail) 9 NA Homo sapiens
GEX166599
HDL cholesterol Newly identified loci that influence lipid concentrations and risk of coronary artery disease. (more detail) 9 18193043 Homo sapiens
TAX025466
GO:0046130 biological process purine ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucle (more detail) 9 NA Homo sapiens
TAX031751
GO:0150065 biological process regulation of deacetylase activity Any process that modulates the frequency, rate or extent of deacetylase activity. (more detail) 9 NA Homo sapiens
WAG001543
Pyrimidine biosynthesis (interconversion) (more detail) 9 NA Homo sapiens
MEX000784
Genes associated with Approved Drug naproxen Genes associated with Approved Drug naproxen, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX000164
Genes associated with Approved Drug phenelzine Genes associated with Approved Drug phenelzine, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MOX003018
Genes associated with Computational Drug Signature Dipropyl phthalate Genes associated with Computational Drug Signature Dipropyl phthalate, curated by the Drug Signature (more detail) 9 25990557 Homo sapiens
TAX022427
GO:0034350 biological process regulation of glial cell apoptotic process Any process that modulates the frequency, rate, or extent of glial cell apoptotic process. (more detail) 9 NA Homo sapiens
TAX017556
GO:0009158 biological process ribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a (more detail) 9 NA Homo sapiens
TAX017566
GO:0009169 biological process purine ribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphat (more detail) 9 NA Homo sapiens
TAX014921
GO:0004022 molecular function alcohol dehydrogenase (NAD) activity Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+. (more detail) 9 NA Homo sapiens
FOX000822
Genes in the cancer module 65 (more detail) 9 NA Homo sapiens
MOX006175
Genes associated with Computational Drug Signature 5 (Nonyloxy)tryptamine Genes associated with Computational Drug Signature 5-(Nonyloxy)tryptamine, curated by the Drug Signa (more detail) 9 25990557 Homo sapiens
TAX018217
GO:0010912 biological process positive regulation of isomerase activity Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or str (more detail) 9 NA Homo sapiens
TAX027572
GO:0055091 biological process phospholipid homeostasis Any process involved in the maintenance of an internal steady state of phospholipid within an organi (more detail) 9 NA Homo sapiens
TAX020167
GO:0022038 biological process corpus callosum development The process whose specific outcome is the progression of the corpus callosum over time, from its for (more detail) 9 NA Homo sapiens
TAX016157
GO:0006152 biological process purine nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family (more detail) 9 NA Homo sapiens
MOX016736
Genes associated with Computational Drug Signature dihydroergotamine Genes associated with Computational Drug Signature dihydroergotamine, curated by the Drug Signature (more detail) 9 25990557 Homo sapiens
MOX012718
Genes associated with Computational Drug Signature fluorescein Genes associated with Computational Drug Signature fluorescein, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
WAG000092
Gamma carboxylation of protein precursors (more detail) 9 NA Homo sapiens
MEX000624
Genes associated with Approved Drug clopidogrel Genes associated with Approved Drug clopidogrel, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MOX001107
Genes associated with Computational Drug Signature VINCLOZOLIN Genes associated with Computational Drug Signature VINCLOZOLIN, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
MOX005078
Genes associated with Computational Drug Signature oxiglutatione Genes associated with Computational Drug Signature oxiglutatione, curated by the Drug Signature Data (more detail) 9 25990557 Homo sapiens
MOX006632
Genes associated with Computational Drug Signature Adenosine diphosphate Genes associated with Computational Drug Signature Adenosine diphosphate, curated by the Drug Signat (more detail) 9 25990557 Homo sapiens
MOX003167
Genes associated with Computational Drug Signature Almotriptan Genes associated with Computational Drug Signature Almotriptan, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
MOX012289
Genes associated with Computational Drug Signature DIETHYLENETRIAMINE Genes associated with Computational Drug Signature DIETHYLENETRIAMINE, curated by the Drug Signature (more detail) 9 25990557 Homo sapiens
MOX010669
Genes associated with Computational Drug Signature CHEMBL448246 Genes associated with Computational Drug Signature CHEMBL448246, curated by the Drug Signature Datab (more detail) 9 25990557 Homo sapiens
MOX002137
Genes associated with Computational Drug Signature Dipropyl 5 CT Genes associated with Computational Drug Signature Dipropyl-5-CT, curated by the Drug Signature Data (more detail) 9 25990557 Homo sapiens
MOX012774
Genes associated with Computational Drug Signature Fulvestrant Genes associated with Computational Drug Signature Fulvestrant, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
WIG000193
VEGF and VEGFR signaling network (more detail) 9 NA Homo sapiens
WIG001309
Genes involved in Tryptophan catabolism (more detail) 9 NA Homo sapiens
MOX004089
Genes associated with Computational Drug Signature fenoprofen Genes associated with Computational Drug Signature fenoprofen, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens
MOX001138
Genes associated with Computational Drug Signature 4 Hydroxyestrone Genes associated with Computational Drug Signature 4-Hydroxyestrone, curated by the Drug Signature D (more detail) 9 25990557 Homo sapiens
MOX005589
Genes associated with Computational Drug Signature 2,6 Di tert butyl 4 methylphenol Genes associated with Computational Drug Signature 2,6-Di-tert-butyl-4-methylphenol, curated by the (more detail) 9 25990557 Homo sapiens
MOX013660
Genes associated with Computational Drug Signature Methoxybufotenin Genes associated with Computational Drug Signature Methoxybufotenin, curated by the Drug Signature D (more detail) 9 25990557 Homo sapiens
MOX013567
Genes associated with Computational Drug Signature Manidipine dihydrochloride Genes associated with Computational Drug Signature Manidipine dihydrochloride, curated by the Drug S (more detail) 9 25990557 Homo sapiens
TAX016405
GO:0006538 biological process glutamate catabolic process The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopen (more detail) 9 NA Homo sapiens
TAX018216
GO:0010911 biological process regulation of isomerase activity Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or str (more detail) 9 NA Homo sapiens
TAX014726
GO:0003373 biological process dynamin family protein polymerization involved in membrane fission The process of creating dynamin family protein polymers, compounds composed of a large number of dyn (more detail) 9 NA Homo sapiens
MOX015748
Genes associated with Computational Drug Signature UNII J8AY0Z4CBP Genes associated with Computational Drug Signature UNII-J8AY0Z4CBP, curated by the Drug Signature Da (more detail) 9 25990557 Homo sapiens
MOX015544
Genes associated with Computational Drug Signature ticlopidine Genes associated with Computational Drug Signature ticlopidine, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
MOX014217
Genes associated with Computational Drug Signature OCHRATOXIN A Genes associated with Computational Drug Signature OCHRATOXIN A, curated by the Drug Signature Datab (more detail) 9 25990557 Homo sapiens
MEX000314
Genes associated with Approved Drug tazarotene Genes associated with Approved Drug tazarotene, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX000326
Genes associated with Approved Drug tolazamide Genes associated with Approved Drug tolazamide, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MOX000336
Genes associated with Computational Drug Signature estradiol cypionate Genes associated with Computational Drug Signature estradiol cypionate, curated by the Drug Signatur (more detail) 9 25990557 Homo sapiens
TAX030624
GO:0097001 molecular function ceramide binding Interacting selectively and non-covalently with any ceramide, a class of lipids that is composed of (more detail) 9 NA Homo sapiens
TAX031369
GO:0099509 biological process regulation of presynaptic cytosolic calcium ion concentration Any process that regulates the concentration of calcium in the presynaptic cytosol. (more detail) 9 NA Homo sapiens
TAX025438
GO:0046085 biological process adenosine metabolic process The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found wi (more detail) 9 NA Homo sapiens
TAX014727
GO:0003374 biological process dynamin family protein polymerization involved in mitochondrial fission The process of creating dynamin protein family polymers, compounds composed of a large number of dyn (more detail) 9 NA Homo sapiens
MOX016671
Genes associated with Computational Drug Signature dTTP Genes associated with Computational Drug Signature dTTP, curated by the Drug Signature Database (DSi (more detail) 9 25990557 Homo sapiens
MOX017827
Genes associated with Computational Drug Signature tetrahydrofolate Genes associated with Computational Drug Signature tetrahydrofolate, curated by the Drug Signature D (more detail) 9 25990557 Homo sapiens
GEX000878
hypertriglyceridemia hypertriglyceridemia associated genes. PAGER constructed this gene set by grouping all genes which a (more detail) 9 NA Homo sapiens
MEX000560
Genes associated with Approved Drug halofantrine hydrochloride Genes associated with Approved Drug halofantrine hydrochloride, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
MEX001260
Genes associated with Kinase Inhibitor Sunitinib Genes associated with Kinase Inhibitor Sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001148
Genes associated with Approved Drug cefoxitin sodium Genes associated with Approved Drug cefoxitin sodium, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MOX003612
Genes associated with Computational Drug Signature ACENOCOUMAROL Genes associated with Computational Drug Signature ACENOCOUMAROL, curated by the Drug Signature Data (more detail) 9 25990557 Homo sapiens
MEX001682
Genes associated with Kinase Inhibitor 7 Hydroxystaurosporine Genes associated with Kinase Inhibitor 7-Hydroxystaurosporine, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens
MOX004379
Genes associated with Computational Drug Signature dimethyl [4 (methylamino) 4 oxobut 2 en 2 yl] phosphate Genes associated with Computational Drug Signature dimethyl [4-(methylamino)-4-oxobut-2-en-2-yl] pho (more detail) 9 25990557 Homo sapiens
MOX004502
Genes associated with Computational Drug Signature Phenelzine Genes associated with Computational Drug Signature Phenelzine, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens
MOX002276
Genes associated with Computational Drug Signature Benidipine Genes associated with Computational Drug Signature Benidipine, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens
TAX027430
GO:0052696 biological process flavonoid glucuronidation The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucu (more detail) 9 NA Homo sapiens
PEX001455
Gelsolin: Gelsolin repeat (more detail) 9 NA Homo sapiens
MOX016178
Genes associated with Computational Drug Signature ZILEUTON Genes associated with Computational Drug Signature ZILEUTON, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens
MOX014863
Genes associated with Computational Drug Signature rockout Genes associated with Computational Drug Signature rockout, curated by the Drug Signature Database ( (more detail) 9 25990557 Homo sapiens
TAX023796
GO:0042363 biological process fat soluble vitamin catabolic process The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins (more detail) 9 NA Homo sapiens
GEX000594
dna dna associated genes. PAGER constructed this gene set by grouping all genes which are associated wit (more detail) 9 NA Homo sapiens
MEX000225
Genes associated with Approved Drug minoxidil Genes associated with Approved Drug minoxidil, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
TAX029380
GO:0071313 biological process cellular response to caffeine Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 9 NA Homo sapiens
IEI004318
Protein protein interactors of human gene ETFBKMT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ETFBKMT (SwissProt I (more detail) 9 17535438 Homo sapiens
IEI003981
Protein protein interactors of human gene EFNA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFNA4 (SwissProt ID= (more detail) 9 17535438 Homo sapiens
TAX033659
GO:1904869 biological process regulation of protein localization to Cajal body Any process that modulates the frequency, rate or extent of protein localization to Cajal body. (more detail) 9 NA Homo sapiens
TAX033660
GO:1904871 biological process positive regulation of protein localization to Cajal body Any process that activates or increases the frequency, rate or extent of protein localization to Caj (more detail) 9 NA Homo sapiens
IEI014238
Protein protein interactors of human gene TRIM34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM34 (SwissProt ID (more detail) 9 17535438 Homo sapiens
IEI014051
Protein protein interactors of human gene TNNT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNNT2 (SwissProt ID= (more detail) 11 17535438 Homo sapiens
IEI001688
Protein protein interactors of human gene CABP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CABP1 (SwissProt ID= (more detail) 11 17535438 Homo sapiens
IEI001257
Protein protein interactors of human gene BCAN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCAN (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens
IEI003034
Protein protein interactors of human gene CSAD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CSAD (SwissProt ID=Q (more detail) 11 17535438 Homo sapiens
IEI000846
Protein protein interactors of human gene ARHGEF25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARHGEF25 (SwissProt (more detail) 11 17535438 Homo sapiens
MOX003674
Genes associated with Computational Drug Signature amoxicillin Genes associated with Computational Drug Signature amoxicillin, curated by the Drug Signature Databa (more detail) 11 25990557 Homo sapiens
MAX003204
Genes down regulated in NB4 cells (acute promyelocytic leukemia, APL) by tretinoin [PubChem=444795] alone. Differentiation induction is an effective therapy for acute promyelocytic leukemia (APL), which dram (more detail) 11 NA Homo sapiens
MOX001108
Genes associated with Computational Drug Signature Arsenic acid Genes associated with Computational Drug Signature Arsenic acid, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens
MOX002801
Genes associated with Computational Drug Signature 2 Ethylhexyl 2 cyano 3,3 diphenylacrylate Genes associated with Computational Drug Signature 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate, curate (more detail) 11 25990557 Homo sapiens
MOX012849
Genes associated with Computational Drug Signature Glaucine Methiodide Genes associated with Computational Drug Signature Glaucine Methiodide, curated by the Drug Signatur (more detail) 11 25990557 Homo sapiens
MOX002556
Genes associated with Computational Drug Signature XANOMELINE Genes associated with Computational Drug Signature XANOMELINE, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens
TAX031168
GO:0098856 biological process intestinal lipid absorption Any process in which lipids are taken up from the contents of the intestine. (more detail) 11 NA Homo sapiens
TAX027085
GO:0051593 biological process response to folic acid Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 11 NA Homo sapiens
TAX026404
GO:0050072 molecular function m7G(5')pppN diphosphatase activity Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosi (more detail) 11 NA Homo sapiens
MOX011936
Genes associated with Computational Drug Signature Chlorpyrifos oxon Genes associated with Computational Drug Signature Chlorpyrifos oxon, curated by the Drug Signature (more detail) 11 25990557 Homo sapiens
FOX000786
Genes in the cancer module 528 (more detail) 11 NA Homo sapiens
MOX003596
Genes associated with Computational Drug Signature Bisphenol AF Genes associated with Computational Drug Signature Bisphenol AF, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens
MOX004688
Genes associated with Computational Drug Signature streptonigrin Genes associated with Computational Drug Signature streptonigrin, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens
TAX023196
GO:0035999 biological process tetrahydrofolate interconversion The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydr (more detail) 11 NA Homo sapiens
MOX015826
Genes associated with Computational Drug Signature Vatalanib succinate Genes associated with Computational Drug Signature Vatalanib succinate, curated by the Drug Signatur (more detail) 11 25990557 Homo sapiens
TAX001373
Genes annotated by the GO term GO:0004993. Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity. (more detail) 11 NA Homo sapiens
MOX003625
Genes associated with Computational Drug Signature aconitine Genes associated with Computational Drug Signature aconitine, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens
MOX002483
Genes associated with Computational Drug Signature 2 Propenamide, 2 cyano 3 (3,4 dihydroxy 5 nitrophenyl) N,N diethyl Genes associated with Computational Drug Signature 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitroph (more detail) 11 25990557 Homo sapiens
MOX004570
Genes associated with Computational Drug Signature PRIMAQUINE Genes associated with Computational Drug Signature PRIMAQUINE, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens
TAX016547
GO:0006707 biological process cholesterol catabolic process The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-o (more detail) 11 NA Homo sapiens
GEX167625
Mean platelet volume A meta-analysis and genome-wide association study of platelet count and mean platelet volume in afri (more detail) 11 22423221 Homo sapiens
TAX033388
GO:1904321 biological process response to forskolin Any process that results in a change in state or activity of a cell or an organism (in terms of move (more detail) 11 NA Homo sapiens
TAX033389
GO:1904322 biological process cellular response to forskolin Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 11 NA Homo sapiens
TAX015294
GO:0004652 molecular function polynucleotide adenylyltransferase activity Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition o (more detail) 11 NA Homo sapiens
WIG000283
Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway Map kinases transduce responses to extracellular signals by a variety of routes, and communicate wit (more detail) 11 NA Homo sapiens
MAX002741
Pre mitotic cell cycle regulators (CDC) identified in an shRNA screen of the ubiquitin pathway components. The spindle checkpoint prevents chromosome mis-segregation by delaying sister chromatid separation u (more detail) 11 NA Homo sapiens
TAX026590
GO:0050786 molecular function RAGE receptor binding Interacting selectively and non-covalently with the RAGE receptor, the receptor for advanced glycati (more detail) 11 NA Homo sapiens
TAX025414
GO:0046051 biological process UTP metabolic process The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate. (more detail) 11 NA Homo sapiens
TAX020664
GO:0030850 biological process prostate gland development The process whose specific outcome is the progression of the prostate gland over time, from its form (more detail) 11 NA Homo sapiens
TAX016175
GO:0006183 biological process GTP biosynthetic process The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate. (more detail) 11 NA Homo sapiens
FOX000544
Genes in the cancer module 211 (more detail) 11 NA Homo sapiens
TAX019284
GO:0016888 molecular function endodeoxyribonuclease activity, producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal bre (more detail) 11 NA Homo sapiens
TAX025410
GO:0046040 biological process IMP metabolic process The chemical reactions and pathways involving IMP, inosine monophosphate. (more detail) 11 NA Homo sapiens
GEX000225
behcet's disease behcet's disease associated genes. PAGER constructed this gene set by grouping all genes which are a (more detail) 11 NA Homo sapiens
WAG000849
phospholipase c epsilon pathway Proposed model for b2-AR- and prostanoid-receptor-mediated PLC and calcium siglling. Receptors coup (more detail) 11 NA Homo sapiens
MOX002475
Genes associated with Computational Drug Signature (5 methyl 3 (morpholinomethyl) 2,3 dihydro [1,4]oxazino[2,3,4 hi]indol 6 yl)(naphthalen 1 yl)methanone Genes associated with Computational Drug Signature (5-methyl-3-(morpholinomethyl)-2,3-dihydro-[1,4]o (more detail) 11 25990557 Homo sapiens
TAX018377
GO:0014819 biological process regulation of skeletal muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction. (more detail) 11 NA Homo sapiens
TAX018881
GO:0016127 biological process sterol catabolic process The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more (more detail) 11 NA Homo sapiens
MOX016777
Genes associated with Computational Drug Signature alpha Ecdysone Genes associated with Computational Drug Signature alpha-Ecdysone, curated by the Drug Signature Dat (more detail) 11 25990557 Homo sapiens
PEX000515
PWWP: PWWP domain The PWWP domain is named after a conserved Pro-Trp-Trp-Pro motif 1. The domain binds to Histone-4 me (more detail) 11 NA Homo sapiens
MOX014035
Genes associated with Computational Drug Signature nilutamide Genes associated with Computational Drug Signature nilutamide, curated by the Drug Signature Databas (more detail) 11 25990557 Homo sapiens
WIG000378
Monocyte and its Surface Molecules Monocytes are a class of phagocytes involved in non-specific immune defense that develop into macrop (more detail) 11 NA Homo sapiens
WIG000310
Regulation of eIF2 Protein phosphorylation plays an important role in the control of translation by eukaryotic initiati (more detail) 11 NA Homo sapiens
MEX000552
Genes associated with Approved Drug zidovudine Genes associated with Approved Drug zidovudine, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX000236
Genes associated with Approved Drug nilutamide Genes associated with Approved Drug nilutamide, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MOX000213
Genes associated with Computational Drug Signature TRIPHENYL PHOSPHATE Genes associated with Computational Drug Signature TRIPHENYL PHOSPHATE, curated by the Drug Signatur (more detail) 11 25990557 Homo sapiens
MEX002453
Genes associated with Perturbagen Signature 10 methoxyharmalan Genes associated with Perturbagen Signature 10-methoxyharmalan, curated by the Drug Signature Databa (more detail) 11 25990557 Homo sapiens
MOX001070
Genes associated with Computational Drug Signature 1,3,5[10] Estratriene 2,3 diol 17 one Genes associated with Computational Drug Signature 1,3,5[10]-Estratriene-2,3-diol-17-one, curated by (more detail) 11 25990557 Homo sapiens
TAX000802
Genes annotated by the GO term GO:0006100. The chemical reactions and pathways involving intermediates of the tricarboxylic acid cycle. (more detail) 11 NA Homo sapiens
TAX021272
GO:0031996 molecular function thioesterase binding Interacting selectively and non-covalently with any thioesterase enzyme. (more detail) 11 NA Homo sapiens
WAG001311
Common Pathway (more detail) 11 NA Homo sapiens
-->
Sorry, no more than 100 PAGs View PAGs' network View gene set network
Sorry, no more than 125 PAGs
A PHP Error was encountered
Severity: Warning
Message: urlencode() expects parameter 1 to be string, array given
Filename: browse/gs_result.php
Line Number: 938
A PHP Error was encountered
Severity: Warning
Message: urlencode() expects parameter 1 to be string, array given
Filename: browse/gs_result.php
Line Number: 946
GOA 
