Y-U
(more detail)
439 NA Homo sapiens
TAX019482
GO:0018193 biological process peptidyl amino acid modification The alteration of an amino acid residue in a peptide. (more detail) 844 NA Homo sapiens
TAX015788
GO:0005524 molecular function ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally import (more detail) 1460 NA Homo sapiens
TAX021636
GO:0032559 molecular function adenyl ribonucleotide binding Interacting selectively and non-covalently with an adenyl ribonucleotide, any compound consisting of (more detail) 1510 NA Homo sapiens
TAX020566
GO:0030554 molecular function adenyl nucleotide binding Interacting selectively and non-covalently with adenyl nucleotides, any compound consisting of adeno (more detail) 1520 NA Homo sapiens
TAX017088
GO:0008144 molecular function drug binding Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substan (more detail) 1709 NA Homo sapiens
TAX001431
Genes annotated by the GO term GO:0016772. Catalysis of the transfer of a phosphorus containing group from one compound (donor) to another (acceptor). (more detail) 419 NA Homo sapiens
TAX021555
GO:0032446 biological process protein modification by small protein conjugation A protein modification process in which one or more groups of a small protein, such as ubiquitin or (more detail) 671 NA Homo sapiens
TAX019094
GO:0016567 biological process protein ubiquitination The process in which one or more ubiquitin groups are added to a protein. (more detail) 621 NA Homo sapiens
FEX002708
Manning02 624genes ProteinKinases protein kinases : The protein kinase complement of the human genome (more detail) 363 12471243 Homo sapiens
TAX023000
GO:0035639 molecular function purine ribonucleoside triphosphate binding Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound con (more detail) 1788 NA Homo sapiens
TAX021632
GO:0032555 molecular function purine ribonucleotide binding Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of (more detail) 1845 NA Homo sapiens
TAX021630
GO:0032553 molecular function ribonucleotide binding Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribon (more detail) 1860 NA Homo sapiens
TAX019366
GO:0017076 molecular function purine nucleotide binding Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a pur (more detail) 1856 NA Homo sapiens
TAX001221
Genes annotated by the GO term GO:0016301. Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. (more detail) 364 NA Homo sapiens
TAX023252
GO:0036094 molecular function small molecule binding Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeri (more detail) 2457 NA Homo sapiens
TAX013287
GO:0000166 molecular function nucleotide binding Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleosid (more detail) 2091 NA Homo sapiens
TAX032073
GO:1901265 molecular function nucleoside phosphate binding Interacting selectively and non-covalently with nucleoside phosphate. (more detail) 2092 NA Homo sapiens
MEX002069
Genes associated with Kinase Inhibitor staurosporine Genes associated with Kinase Inhibitor staurosporine, curated by the Drug Signature Database (DSigDB (more detail) 313 25990557 Homo sapiens
TAX030822
GO:0097367 molecular function carbohydrate derivative binding Interacting selectively and non-covalently with a carbohydrate derivative. (more detail) 2148 NA Homo sapiens
TAX029048
GO:0070647 biological process protein modification by small protein conjugation or removal A protein modification process in which one or more groups of a small protein, such as ubiquitin or (more detail) 921 NA Homo sapiens
TAX001314
Genes annotated by the GO term GO:0016773. Catalysis of the transfer of a phosphorus containing group from one compound (donor) to an alcohol group (acceptor). (more detail) 329 NA Homo sapiens
TAX024195
GO:0043168 molecular function anion binding Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net (more detail) 2688 NA Homo sapiens
TAX034193
GO:1990234 cellular component transferase complex A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group (more detail) 724 NA Homo sapiens
TAX019198
GO:0016757 molecular function transferase activity, transferring glycosyl groups Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). (more detail) 286 NA Homo sapiens
MEX002285
Genes associated with Kinase Inhibitor Lestaurtinib Genes associated with Kinase Inhibitor Lestaurtinib, curated by the Drug Signature Database (DSigDB) (more detail) 270 25990557 Homo sapiens
MEX000996
Genes associated with Approved Drug sunitinib Genes associated with Approved Drug sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 256 25990557 Homo sapiens
TAX000053
Genes annotated by the GO term GO:0043412. The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer, resulting in a change in its properties. (more detail) 634 NA Homo sapiens
MEX001673
Genes associated with Kinase Inhibitor SureCN1564574 Genes associated with Kinase Inhibitor SureCN1564574, curated by the Drug Signature Database (DSigDB (more detail) 254 25990557 Homo sapiens
TAX001329
Genes annotated by the GO term GO:0004672. Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. (more detail) 281 NA Homo sapiens
TAX000557
Genes annotated by the GO term GO:0006464. The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co translational, post translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre translation modification). (more detail) 615 NA Homo sapiens
TAX019192
GO:0016746 molecular function transferase activity, transferring acyl groups Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). (more detail) 246 NA Homo sapiens
TAX028530
GO:0061659 molecular function ubiquitin like protein ligase activity Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction (more detail) 236 NA Homo sapiens
TAX028518
GO:0061630 molecular function ubiquitin protein ligase activity Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X (more detail) 231 NA Homo sapiens
MEX001467
Genes associated with Kinase Inhibitor OTSSP167 Genes associated with Kinase Inhibitor OTSSP167, curated by the Drug Signature Database (DSigDB). (more detail) 234 25990557 Homo sapiens
TAX019188
GO:0016741 molecular function transferase activity, transferring one carbon groups Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor). (more detail) 224 NA Homo sapiens
TAX019193
GO:0016747 molecular function transferase activity, transferring acyl groups other than amino acyl groups Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to anot (more detail) 216 NA Homo sapiens
TAX017098
GO:0008168 molecular function methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule. (more detail) 213 NA Homo sapiens
TAX019199
GO:0016758 molecular function transferase activity, transferring hexosyl groups Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). (more detail) 207 NA Homo sapiens
MEX001791
Genes associated with Kinase Inhibitor NVP TAE684 Genes associated with Kinase Inhibitor NVP-TAE684, curated by the Drug Signature Database (DSigDB). (more detail) 210 25990557 Homo sapiens
MEX001635
Genes associated with Kinase Inhibitor BX 912 Genes associated with Kinase Inhibitor BX-912, curated by the Drug Signature Database (DSigDB). (more detail) 203 25990557 Homo sapiens
MEX001224
Genes associated with Kinase Inhibitor NVP TAE684 Genes associated with Kinase Inhibitor NVP-TAE684, curated by the Drug Signature Database (DSigDB). (more detail) 203 25990557 Homo sapiens
MEX001522
Genes associated with Kinase Inhibitor 841290 80 0 Genes associated with Kinase Inhibitor 841290-80-0, curated by the Drug Signature Database (DSigDB). (more detail) 201 25990557 Homo sapiens
TAX000089
Genes annotated by the GO term GO:0044260. The chemical reactions and pathways involving macromolecules, large molecules including proteins, nucleic acids and carbohydrates, as carried out by individual cells. (more detail) 1094 NA Homo sapiens
MEX001777
Genes associated with Kinase Inhibitor HG 14 10 04 Genes associated with Kinase Inhibitor HG-14-10-04, curated by the Drug Signature Database (DSigDB). (more detail) 202 25990557 Homo sapiens
TAX000096
Genes annotated by the GO term GO:0044267. The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification. (more detail) 1080 NA Homo sapiens
MEX000995
Genes associated with Approved Drug bosutinib Genes associated with Approved Drug bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 199 25990557 Homo sapiens
MEX001653
Genes associated with Kinase Inhibitor staurosporine Genes associated with Kinase Inhibitor staurosporine, curated by the Drug Signature Database (DSigDB (more detail) 195 25990557 Homo sapiens
MEX002024
Genes associated with Kinase Inhibitor 841290 80 0 Genes associated with Kinase Inhibitor 841290-80-0, curated by the Drug Signature Database (DSigDB). (more detail) 192 25990557 Homo sapiens
TAX001337
Genes annotated by the GO term GO:0004674. Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate. (more detail) 202 NA Homo sapiens
TAX000052
Genes annotated by the GO term GO:0043283. The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. (more detail) 1637 NA Homo sapiens
TAX000555
Genes annotated by the GO term GO:0019538. The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. (more detail) 1187 NA Homo sapiens
TAX013304
GO:0000209 biological process protein polyubiquitination Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. (more detail) 237 NA Homo sapiens
TAX000530
Genes annotated by the GO term GO:0043687. The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome. (more detail) 462 NA Homo sapiens
TAX025737
GO:0046777 biological process protein autophosphorylation The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylat (more detail) 198 NA Homo sapiens
IEI006058
Protein protein interactors of human gene HSP90AA1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSP90AA1 (SwissProt (more detail) 831 17535438 Homo sapiens
TAX015958
GO:0005829 cellular component cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate (more detail) 4846 NA Homo sapiens
MEX002397
Genes associated with Kinase Inhibitor Sunitinib Genes associated with Kinase Inhibitor Sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 185 25990557 Homo sapiens
IEI006060
Protein protein interactors of human gene HSP90AB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HSP90AB1 (SwissProt (more detail) 703 17535438 Homo sapiens
MEX002276
Genes associated with Kinase Inhibitor Sunitinib Genes associated with Kinase Inhibitor Sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 183 25990557 Homo sapiens
MEX001215
Genes associated with Kinase Inhibitor KW 2449 Genes associated with Kinase Inhibitor KW-2449, curated by the Drug Signature Database (DSigDB). (more detail) 182 25990557 Homo sapiens
TAX032530
GO:1902494 cellular component catalytic complex A protein complex which is capable of catalytic activity. (more detail) 1315 NA Homo sapiens
TAX015338
GO:0004713 molecular function protein tyrosine kinase activity Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. (more detail) 181 NA Homo sapiens
TAX000469
Genes annotated by the GO term GO:0016310. The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. (more detail) 303 NA Homo sapiens
TAX000540
Genes annotated by the GO term GO:0006468. The process of introducing a phosphate group on to a protein. (more detail) 270 NA Homo sapiens
PEX001788
Pkinase: Protein kinase domain (more detail) 165 NA Homo sapiens
TAX017474
GO:0009058 biological process biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-r (more detail) 4323 NA Homo sapiens
TAX032173
GO:1901576 biological process organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of an organic substance, any molecula (more detail) 4266 NA Homo sapiens
TAX021416
GO:0032259 biological process methylation The process in which a methyl group is covalently attached to a molecule. (more detail) 286 NA Homo sapiens
TAX019769
GO:0019637 biological process organophosphate metabolic process The chemical reactions and pathways involving organophosphates, any phosphate-containing organic com (more detail) 922 NA Homo sapiens
TAX019498
GO:0018212 biological process peptidyl tyrosine modification The modification of peptidyl-tyrosine. (more detail) 193 NA Homo sapiens
MEX002280
Genes associated with Kinase Inhibitor Vargatef Genes associated with Kinase Inhibitor Vargatef, curated by the Drug Signature Database (DSigDB). (more detail) 158 25990557 Homo sapiens
MEX002417
Genes associated with Kinase Inhibitor Nintedanib Genes associated with Kinase Inhibitor Nintedanib, curated by the Drug Signature Database (DSigDB). (more detail) 158 25990557 Homo sapiens
TAX019463
GO:0018108 biological process peptidyl tyrosine phosphorylation The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine. (more detail) 190 NA Homo sapiens
TAX017409
GO:0008757 molecular function S adenosylmethionine dependent methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate. (more detail) 157 NA Homo sapiens
MEX001450
Genes associated with Kinase Inhibitor 602306 29 6 Genes associated with Kinase Inhibitor 602306-29-6, curated by the Drug Signature Database (DSigDB). (more detail) 154 25990557 Homo sapiens
TAX019495
GO:0018209 biological process peptidyl serine modification The modification of peptidyl-serine. (more detail) 194 NA Homo sapiens
MEX001768
Genes associated with Kinase Inhibitor HG 9 91 01 Genes associated with Kinase Inhibitor HG-9-91-01, curated by the Drug Signature Database (DSigDB). (more detail) 150 25990557 Homo sapiens
MEX002012
Genes associated with Kinase Inhibitor Foretinib Genes associated with Kinase Inhibitor Foretinib, curated by the Drug Signature Database (DSigDB). (more detail) 149 25990557 Homo sapiens
TAX019460
GO:0018105 biological process peptidyl serine phosphorylation The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine. (more detail) 175 NA Homo sapiens
TAX032019
GO:1901135 biological process carbohydrate derivative metabolic process The chemical reactions and pathways involving carbohydrate derivative. (more detail) 854 NA Homo sapiens
MEX001293
Genes associated with Kinase Inhibitor AST 487 Genes associated with Kinase Inhibitor AST 487, curated by the Drug Signature Database (DSigDB). (more detail) 147 25990557 Homo sapiens
MEX001676
Genes associated with Kinase Inhibitor 627908 92 3 Genes associated with Kinase Inhibitor 627908-92-3, curated by the Drug Signature Database (DSigDB). (more detail) 146 25990557 Homo sapiens
MEX001712
Genes associated with Kinase Inhibitor HG6 64 1 Genes associated with Kinase Inhibitor HG6-64-1, curated by the Drug Signature Database (DSigDB). (more detail) 145 25990557 Homo sapiens
TAX017118
GO:0008194 molecular function UDP glycosyltransferase activity Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule. (more detail) 144 NA Homo sapiens
MEX001115
Genes associated with Approved Drug crizotinib Genes associated with Approved Drug crizotinib, curated by the Drug Signature Database (DSigDB). (more detail) 146 25990557 Homo sapiens
MEX002396
Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 140 25990557 Homo sapiens
TAX024645
GO:0044249 biological process cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individ (more detail) 4154 NA Homo sapiens
MEX002010
Genes associated with Kinase Inhibitor MLS006011171 Genes associated with Kinase Inhibitor MLS006011171, curated by the Drug Signature Database (DSigDB) (more detail) 142 25990557 Homo sapiens
TAX022935
GO:0035556 biological process intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become ac (more detail) 1481 NA Homo sapiens
MEX002403
Genes associated with Kinase Inhibitor Crizotinib Genes associated with Kinase Inhibitor Crizotinib, curated by the Drug Signature Database (DSigDB). (more detail) 137 25990557 Homo sapiens
TAX030531
GO:0090407 biological process organophosphate biosynthetic process The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phos (more detail) 546 NA Homo sapiens
TAX024661
GO:0044281 biological process small molecule metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, (more detail) 1677 NA Homo sapiens
TAX019210
GO:0016779 molecular function nucleotidyltransferase activity Catalysis of the transfer of a nucleotidyl group to a reactant. (more detail) 136 NA Homo sapiens
MEX001285
Genes associated with Kinase Inhibitor WH 4 023 Genes associated with Kinase Inhibitor WH-4-023, curated by the Drug Signature Database (DSigDB). (more detail) 136 25990557 Homo sapiens
MEX001421
Genes associated with Kinase Inhibitor Crizotinib Genes associated with Kinase Inhibitor Crizotinib, curated by the Drug Signature Database (DSigDB). (more detail) 135 25990557 Homo sapiens
MEX001848
Genes associated with Kinase Inhibitor Tg 101348 Genes associated with Kinase Inhibitor Tg-101348, curated by the Drug Signature Database (DSigDB). (more detail) 132 25990557 Homo sapiens
TAX032021
GO:1901137 biological process carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative. (more detail) 443 NA Homo sapiens
TAX013278
GO:0000151 cellular component ubiquitin ligase complex A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase acti (more detail) 304 NA Homo sapiens
TAX024646
GO:0044255 biological process cellular lipid metabolic process The chemical reactions and pathways involving lipids, as carried out by individual cells. (more detail) 938 NA Homo sapiens
MEX001551
Genes associated with Kinase Inhibitor AZD4547 Genes associated with Kinase Inhibitor AZD4547, curated by the Drug Signature Database (DSigDB). (more detail) 126 25990557 Homo sapiens
TAX028722
GO:0070085 biological process glycosylation The covalent attachment and further modification of carbohydrate residues to a substrate molecule. (more detail) 244 NA Homo sapiens
MEX001881
Genes associated with Kinase Inhibitor K 252a, Nocardiopsis sp. Genes associated with Kinase Inhibitor K-252a, Nocardiopsis sp., curated by the Drug Signature Datab (more detail) 125 25990557 Homo sapiens
MEX002327
Genes associated with Kinase Inhibitor Midostaurin Genes associated with Kinase Inhibitor Midostaurin, curated by the Drug Signature Database (DSigDB). (more detail) 125 25990557 Homo sapiens
TAX032166
GO:1901566 biological process organonitrogen compound biosynthetic process The chemical reactions and pathways resulting in the formation of organonitrogen compound. (more detail) 925 NA Homo sapiens
TAX016365
GO:0006486 biological process protein glycosylation A protein modification process that results in the addition of a carbohydrate or carbohydrate deriva (more detail) 233 NA Homo sapiens
TAX024355
GO:0043413 biological process macromolecule glycosylation The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polyn (more detail) 233 NA Homo sapiens
MEX002097
Genes associated with Kinase Inhibitor 1092351 67 1 Genes associated with Kinase Inhibitor 1092351-67-1, curated by the Drug Signature Database (DSigDB) (more detail) 120 25990557 Homo sapiens
MEX002317
Genes associated with Kinase Inhibitor CGP74514A Genes associated with Kinase Inhibitor CGP74514A, curated by the Drug Signature Database (DSigDB). (more detail) 122 25990557 Homo sapiens
MEX001279
Genes associated with Kinase Inhibitor AGN PC 04XSRZ Genes associated with Kinase Inhibitor AGN-PC-04XSRZ, curated by the Drug Signature Database (DSigDB (more detail) 119 25990557 Homo sapiens
MEX002416
Genes associated with Kinase Inhibitor Dabrafenib Genes associated with Kinase Inhibitor Dabrafenib, curated by the Drug Signature Database (DSigDB). (more detail) 121 25990557 Homo sapiens
MEX001869
Genes associated with Kinase Inhibitor Dabrafenib Genes associated with Kinase Inhibitor Dabrafenib, curated by the Drug Signature Database (DSigDB). (more detail) 121 25990557 Homo sapiens
MEX001460
Genes associated with Kinase Inhibitor CP 466722 Genes associated with Kinase Inhibitor CP-466722, curated by the Drug Signature Database (DSigDB). (more detail) 117 25990557 Homo sapiens
MEX001667
Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 116 25990557 Homo sapiens
TAX015894
GO:0005737 cellular component cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcell (more detail) 4130 NA Homo sapiens
MEX002025
Genes associated with Kinase Inhibitor PD173955 Genes associated with Kinase Inhibitor PD173955, curated by the Drug Signature Database (DSigDB). (more detail) 114 25990557 Homo sapiens
TAX017797
GO:0009893 biological process positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 3295 NA Homo sapiens
TAX016484
GO:0006629 biological process lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but no (more detail) 1183 NA Homo sapiens
MEX000921
Genes associated with Approved Drug dasatinib Genes associated with Approved Drug dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 144 25990557 Homo sapiens
TAX024356
GO:0043414 biological process macromolecule methylation The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynuc (more detail) 226 NA Homo sapiens
IEI014567
Protein protein interactors of human gene UBE2D2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2D2 (SwissProt ID (more detail) 211 17535438 Homo sapiens
TAX019492
GO:0018205 biological process peptidyl lysine modification The modification of peptidyl-lysine. (more detail) 256 NA Homo sapiens
TAX024196
GO:0043169 molecular function cation binding Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net (more detail) 4200 NA Homo sapiens
MEX001267
Genes associated with Kinase Inhibitor OTSSP167 Genes associated with Kinase Inhibitor OTSSP167, curated by the Drug Signature Database (DSigDB). (more detail) 108 25990557 Homo sapiens
TAX026202
GO:0048522 biological process positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of a cellular process, any of (more detail) 4935 NA Homo sapiens
TAX025777
GO:0046872 molecular function metal ion binding Interacting selectively and non-covalently with any metal ion. (more detail) 4109 NA Homo sapiens
TAX020967
GO:0031399 biological process regulation of protein modification process Any process that modulates the frequency, rate or extent of the covalent alteration of one or more a (more detail) 1744 NA Homo sapiens
MEX000922
Genes associated with Approved Drug vandetanib Genes associated with Approved Drug vandetanib, curated by the Drug Signature Database (DSigDB). (more detail) 114 25990557 Homo sapiens
TAX001426
Genes annotated by the GO term GO:0016757. Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). (more detail) 111 NA Homo sapiens
TAX026894
GO:0051247 biological process positive regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 1570 NA Homo sapiens
MEX000804
Genes associated with Approved Drug sorafenib Genes associated with Approved Drug sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 115 25990557 Homo sapiens
TAX020925
GO:0031325 biological process positive regulation of cellular metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 3034 NA Homo sapiens
IEI014566
Protein protein interactors of human gene UBE2D1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2D1 (SwissProt ID (more detail) 247 17535438 Homo sapiens
TAX022578
GO:0034641 biological process cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, a (more detail) 4908 NA Homo sapiens
TAX016044
GO:0005975 biological process carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds bas (more detail) 455 NA Homo sapiens
MEX001316
Genes associated with Kinase Inhibitor 405169 16 6 Genes associated with Kinase Inhibitor 405169-16-6, curated by the Drug Signature Database (DSigDB). (more detail) 103 25990557 Homo sapiens
IEI014568
Protein protein interactors of human gene UBE2D3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2D3 (SwissProt ID (more detail) 202 17535438 Homo sapiens
MEX002384
Genes associated with Kinase Inhibitor A 443654 Genes associated with Kinase Inhibitor A-443654, curated by the Drug Signature Database (DSigDB). (more detail) 104 25990557 Homo sapiens
MEX001932
Genes associated with Kinase Inhibitor Crizotinib Genes associated with Kinase Inhibitor Crizotinib, curated by the Drug Signature Database (DSigDB). (more detail) 101 25990557 Homo sapiens
TAX017992
GO:0010604 biological process positive regulation of macromolecule metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 3056 NA Homo sapiens
MEX002187
Genes associated with Kinase Inhibitor Antibiotic K 252a Genes associated with Kinase Inhibitor Antibiotic K 252a, curated by the Drug Signature Database (DS (more detail) 100 25990557 Homo sapiens
MEX001715
Genes associated with Kinase Inhibitor PHA 767491 Genes associated with Kinase Inhibitor PHA-767491, curated by the Drug Signature Database (DSigDB). (more detail) 100 25990557 Homo sapiens
TAX024744
GO:0044428 cellular component nuclear part Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chrom (more detail) 4273 NA Homo sapiens
MEX002223
Genes associated with Kinase Inhibitor CHEMBL1908395 Genes associated with Kinase Inhibitor CHEMBL1908395, curated by the Drug Signature Database (DSigDB (more detail) 99 25990557 Homo sapiens
TAX020229
GO:0023014 biological process signal transduction by protein phosphorylation A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to (more detail) 319 NA Homo sapiens
TAX019001
GO:0016407 molecular function acetyltransferase activity Catalysis of the transfer of an acetyl group to an acceptor molecule. (more detail) 98 NA Homo sapiens
TAX026893
GO:0051246 biological process regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways invo (more detail) 2724 NA Homo sapiens
TAX019004
GO:0016410 molecular function N acyltransferase activity Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule. (more detail) 97 NA Homo sapiens
TAX026848
GO:0051173 biological process positive regulation of nitrogen compound metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and (more detail) 2921 NA Homo sapiens
TAX017100
GO:0008170 molecular function N methyltransferase activity Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. (more detail) 95 NA Homo sapiens
MEX001872
Genes associated with Kinase Inhibitor Cdk1/2 Inhibitor III Genes associated with Kinase Inhibitor Cdk1/2 Inhibitor III, curated by the Drug Signature Database (more detail) 95 25990557 Homo sapiens
TAX017368
GO:0008610 biological process lipid biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an or (more detail) 562 NA Homo sapiens
TAX024488
GO:0043632 biological process modification dependent macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by cova (more detail) 464 NA Homo sapiens
TAX016382
GO:0006511 biological process ubiquitin dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 448 NA Homo sapiens
TAX019889
GO:0019941 biological process modification dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 454 NA Homo sapiens
MEX001763
Genes associated with Kinase Inhibitor PKR Inhibitor Genes associated with Kinase Inhibitor PKR Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 92 25990557 Homo sapiens
MEX001047
Genes associated with Approved Drug axitinib Genes associated with Approved Drug axitinib, curated by the Drug Signature Database (DSigDB). (more detail) 104 25990557 Homo sapiens
TAX025760
GO:0046834 biological process lipid phosphorylation The process of introducing one or more phosphate groups into a lipid, any member of a group of subst (more detail) 112 NA Homo sapiens
WIG000638
Ubiquitin mediated proteolysis Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions (more detail) 130 NA Homo sapiens
MEX002413
Genes associated with Kinase Inhibitor Ponatinib Genes associated with Kinase Inhibitor Ponatinib, curated by the Drug Signature Database (DSigDB). (more detail) 90 25990557 Homo sapiens
TAX017168
GO:0008276 molecular function protein methyltransferase activity Catalysis of the transfer of a methyl group (CH3-) to a protein. (more detail) 90 NA Homo sapiens
WAG000604
Glycan structures biosynthesis 1 (more detail) 104 NA Homo sapiens
MEX001740
Genes associated with Kinase Inhibitor A 770041 Genes associated with Kinase Inhibitor A-770041, curated by the Drug Signature Database (DSigDB). (more detail) 92 25990557 Homo sapiens
TAX025596
GO:0046486 biological process glycerolipid metabolic process The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Dia (more detail) 400 NA Homo sapiens
TAX019096
GO:0016570 biological process histone modification The covalent alteration of one or more amino acid residues within a histone protein. (more detail) 352 NA Homo sapiens
MEX002312
Genes associated with Kinase Inhibitor Tozasertib Genes associated with Kinase Inhibitor Tozasertib, curated by the Drug Signature Database (DSigDB). (more detail) 87 25990557 Homo sapiens
TAX019095
GO:0016569 biological process covalent chromatin modification The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups (more detail) 362 NA Homo sapiens
MEX001604
Genes associated with Kinase Inhibitor BRD K29385665 001 01 1 Genes associated with Kinase Inhibitor BRD-K29385665-001-01-1, curated by the Drug Signature Databas (more detail) 86 25990557 Homo sapiens
WAG000988
Ubiquitin mediated proteolysis Protein ubiquitition plays an important role in eukaryotic cellular processes. It mainly functions a (more detail) 121 NA Homo sapiens
MEX001926
Genes associated with Kinase Inhibitor AGN PC 045KSD Genes associated with Kinase Inhibitor AGN-PC-045KSD, curated by the Drug Signature Database (DSigDB (more detail) 85 25990557 Homo sapiens
TAX016498
GO:0006650 biological process glycerophospholipid metabolic process The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophospha (more detail) 332 NA Homo sapiens
TAX019496
GO:0018210 biological process peptidyl threonine modification The modification of peptidyl-threonine. (more detail) 86 NA Homo sapiens
MEX001819
Genes associated with Kinase Inhibitor Palbociclib Genes associated with Kinase Inhibitor Palbociclib, curated by the Drug Signature Database (DSigDB). (more detail) 83 25990557 Homo sapiens
MEX002400
Genes associated with Kinase Inhibitor Palbociclib Genes associated with Kinase Inhibitor Palbociclib, curated by the Drug Signature Database (DSigDB). (more detail) 83 25990557 Homo sapiens
MEX001840
Genes associated with Kinase Inhibitor SB 218078 Genes associated with Kinase Inhibitor SB 218078, curated by the Drug Signature Database (DSigDB). (more detail) 83 25990557 Homo sapiens
MEX002344
Genes associated with Kinase Inhibitor staurosporine Genes associated with Kinase Inhibitor staurosporine, curated by the Drug Signature Database (DSigDB (more detail) 82 25990557 Homo sapiens
TAX028544
GO:0061695 cellular component transferase complex, transferring phosphorus containing groups A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one (more detail) 190 NA Homo sapiens
MEX002399
Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 81 25990557 Homo sapiens
MEX002053
Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 81 25990557 Homo sapiens
TAX017049
GO:0008080 molecular function N acetyltransferase activity Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. (more detail) 81 NA Homo sapiens
TAX013286
GO:0000165 biological process MAPK cascade An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade (more detail) 294 NA Homo sapiens
MEX001415
Genes associated with Kinase Inhibitor Kinome 3629 Genes associated with Kinase Inhibitor Kinome_3629, curated by the Drug Signature Database (DSigDB). (more detail) 80 25990557 Homo sapiens
MEX001982
Genes associated with Kinase Inhibitor Aurora A Inhibitor I Genes associated with Kinase Inhibitor Aurora A Inhibitor I, curated by the Drug Signature Database (more detail) 80 25990557 Homo sapiens
TAX025771
GO:0046854 biological process phosphatidylinositol phosphorylation The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophos (more detail) 100 NA Homo sapiens
TAX016555
GO:0006725 biological process cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized (more detail) 4620 NA Homo sapiens
TAX032108
GO:1901360 biological process organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound. (more detail) 4827 NA Homo sapiens
TAX017939
GO:0010498 biological process proteasomal protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 279 NA Homo sapiens
MOX013004
Genes associated with Computational Drug Signature hesperadin Genes associated with Computational Drug Signature hesperadin, curated by the Drug Signature Databas (more detail) 79 25990557 Homo sapiens
TAX022690
GO:0035004 molecular function phosphatidylinositol 3 kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. (more detail) 79 NA Homo sapiens
TAX025594
GO:0046483 biological process heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular (more detail) 4579 NA Homo sapiens
MEX001742
Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 78 25990557 Homo sapiens
TAX019627
GO:0019199 molecular function transmembrane receptor protein kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to in (more detail) 77 NA Homo sapiens
TAX019462
GO:0018107 biological process peptidyl threonine phosphorylation The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. (more detail) 79 NA Homo sapiens
MEX000761
Genes associated with Approved Drug gefitinib Genes associated with Approved Drug gefitinib, curated by the Drug Signature Database (DSigDB). (more detail) 88 25990557 Homo sapiens
PEX002586
Pkinase Tyr: Protein tyrosine kinase (more detail) 76 NA Homo sapiens
MEX001238
Genes associated with Kinase Inhibitor A 674563 Genes associated with Kinase Inhibitor A-674563, curated by the Drug Signature Database (DSigDB). (more detail) 75 25990557 Homo sapiens
TAX001428
Genes annotated by the GO term GO:0016758. Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). (more detail) 80 NA Homo sapiens
TAX021916
GO:0032991 cellular component protein containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipi (more detail) 4915 NA Homo sapiens
TAX016151
GO:0006139 biological process nucleobase containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. (more detail) 4414 NA Homo sapiens
TAX026231
GO:0048583 biological process regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to st (more detail) 4003 NA Homo sapiens
TAX017393
GO:0008654 biological process phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containin (more detail) 259 NA Homo sapiens
TAX024191
GO:0043161 biological process proteasome mediated ubiquitin dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 257 NA Homo sapiens
TAX021009
GO:0031461 cellular component cullin RING ubiquitin ligase complex Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family a (more detail) 176 NA Homo sapiens
TAX027456
GO:0052813 molecular function phosphatidylinositol bisphosphate kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol bisphosphate = ADP + a phosphatidylinositol (more detail) 71 NA Homo sapiens
TAX019213
GO:0016782 molecular function transferase activity, transferring sulfur containing groups Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (accepto (more detail) 71 NA Homo sapiens
TAX017133
GO:0008213 biological process protein alkylation The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an (more detail) 123 NA Homo sapiens
TAX016361
GO:0006479 biological process protein methylation The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by th (more detail) 123 NA Homo sapiens
TAX020411
GO:0030258 biological process lipid modification The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properti (more detail) 243 NA Homo sapiens
MAX000766
Genes required for proliferation of DLD 1 cell (colon cancer with APC [GeneID=324] deletions), based on shRNA screen. Aberrant activation of the canonical WNT/beta-catenin pathway occurs in almost all colorectal cancer (more detail) 165 NA Homo sapiens
TAX025598
GO:0046488 biological process phosphatidylinositol metabolic process The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a (more detail) 208 NA Homo sapiens
TAX016809
GO:0007165 biological process signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a (more detail) 4709 NA Homo sapiens
TAX025818
GO:0046934 molecular function phosphatidylinositol 4,5 bisphosphate 3 kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl- (more detail) 68 NA Homo sapiens
WIG000698
Genes involved in Antigen processing: Ubiquitination & Proteasome degradation (more detail) 199 NA Homo sapiens
TAX019201
GO:0016765 molecular function transferase activity, transferring alkyl or aryl (other than methyl) groups Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to an (more detail) 67 NA Homo sapiens
TAX024432
GO:0043543 biological process protein acylation The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to (more detail) 166 NA Homo sapiens
TAX022372
GO:0034212 molecular function peptide N acetyltransferase activity Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reac (more detail) 66 NA Homo sapiens
MEX001550
Genes associated with Kinase Inhibitor Cyt387 Genes associated with Kinase Inhibitor Cyt387, curated by the Drug Signature Database (DSigDB). (more detail) 65 25990557 Homo sapiens
IEI014571
Protein protein interactors of human gene UBE2E1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2E1 (SwissProt ID (more detail) 125 17535438 Homo sapiens
MEX001346
Genes associated with Kinase Inhibitor WZ4002 Genes associated with Kinase Inhibitor WZ4002, curated by the Drug Signature Database (DSigDB). (more detail) 64 25990557 Homo sapiens
MEX002134
Genes associated with Kinase Inhibitor BRD K83972459 001 01 9 Genes associated with Kinase Inhibitor BRD-K83972459-001-01-9, curated by the Drug Signature Databas (more detail) 64 25990557 Homo sapiens
MEX002414
Genes associated with Kinase Inhibitor Ruzolitinib Genes associated with Kinase Inhibitor Ruzolitinib, curated by the Drug Signature Database (DSigDB). (more detail) 63 25990557 Homo sapiens
MEX002376
Genes associated with Kinase Inhibitor PHA 665752 Genes associated with Kinase Inhibitor PHA-665752, curated by the Drug Signature Database (DSigDB). (more detail) 63 25990557 Homo sapiens
TAX018953
GO:0016278 molecular function lysine N methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group (more detail) 63 NA Homo sapiens
MEX001850
Genes associated with Kinase Inhibitor AGN PC 0D0DBW Genes associated with Kinase Inhibitor AGN-PC-0D0DBW, curated by the Drug Signature Database (DSigDB (more detail) 62 25990557 Homo sapiens
TAX018954
GO:0016279 molecular function protein lysine N methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group (more detail) 62 NA Homo sapiens
TAX026199
GO:0048519 biological process negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. (more detail) 4829 NA Homo sapiens
TAX017103
GO:0008173 molecular function RNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule. (more detail) 61 NA Homo sapiens
TAX015339
GO:0004714 molecular function transmembrane receptor protein tyrosine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to in (more detail) 61 NA Homo sapiens
MEX001543
Genes associated with Kinase Inhibitor Ruxolitinib Genes associated with Kinase Inhibitor Ruxolitinib, curated by the Drug Signature Database (DSigDB). (more detail) 61 25990557 Homo sapiens
MEX002406
Genes associated with Kinase Inhibitor Sorafenib Genes associated with Kinase Inhibitor Sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 59 25990557 Homo sapiens
TAX023646
GO:0042054 molecular function histone methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-hi (more detail) 59 NA Homo sapiens
IEI014569
Protein protein interactors of human gene UBE2D4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2D4 (SwissProt ID (more detail) 98 17535438 Homo sapiens
TAX028564
GO:0061733 molecular function peptide lysine N acetyltransferase activity Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide. (more detail) 58 NA Homo sapiens
TAX027224
GO:0051865 biological process protein autoubiquitination The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an ide (more detail) 58 NA Homo sapiens
MEX002129
Genes associated with Kinase Inhibitor Flavopiridol Genes associated with Kinase Inhibitor Flavopiridol, curated by the Drug Signature Database (DSigDB) (more detail) 58 25990557 Homo sapiens
TAX001090
Genes annotated by the GO term GO:0005524. Interacting selectively with ATP, adenosine 5' triphosphate, a universally important coenzyme and enzyme regulator. (more detail) 151 NA Homo sapiens
TAX001070
Genes annotated by the GO term GO:0032559. Interacting selectively with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. (more detail) 158 NA Homo sapiens
TAX019200
GO:0016763 molecular function transferase activity, transferring pentosyl groups Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). (more detail) 57 NA Homo sapiens
TAX001069
Genes annotated by the GO term GO:0030554. Interacting selectively with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate. (more detail) 164 NA Homo sapiens
MEX001357
Genes associated with Kinase Inhibitor BX 795 Genes associated with Kinase Inhibitor BX-795, curated by the Drug Signature Database (DSigDB). (more detail) 56 25990557 Homo sapiens
TAX015116
GO:0004402 molecular function histone acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone. (more detail) 56 NA Homo sapiens
MOX015198
Genes associated with Computational Drug Signature staurosporine Genes associated with Computational Drug Signature staurosporine, curated by the Drug Signature Data (more detail) 120 25990557 Homo sapiens
MEX001456
Genes associated with Kinase Inhibitor Vandetanib Genes associated with Kinase Inhibitor Vandetanib, curated by the Drug Signature Database (DSigDB). (more detail) 55 25990557 Homo sapiens
MEX002358
Genes associated with Kinase Inhibitor JAK3 Inhibitor VI Genes associated with Kinase Inhibitor JAK3 Inhibitor VI, curated by the Drug Signature Database (DS (more detail) 55 25990557 Homo sapiens
MEX002061
Genes associated with Kinase Inhibitor 878739 06 1 Genes associated with Kinase Inhibitor 878739-06-1, curated by the Drug Signature Database (DSigDB). (more detail) 55 25990557 Homo sapiens
MEX001371
Genes associated with Kinase Inhibitor Sorafenib Genes associated with Kinase Inhibitor Sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 55 25990557 Homo sapiens
MEX002395
Genes associated with Kinase Inhibitor Vandetanib Genes associated with Kinase Inhibitor Vandetanib, curated by the Drug Signature Database (DSigDB). (more detail) 55 25990557 Homo sapiens
WIG001989
Insulin Signaling Insulin Signaling (more detail) 159 NA Homo sapiens
TAX001424
Genes annotated by the GO term GO:0016746. Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). (more detail) 59 NA Homo sapiens
TAX027442
GO:0052742 molecular function phosphatidylinositol kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate. (more detail) 54 NA Homo sapiens
MEX001204
Genes associated with Kinase Inhibitor Ro 31 8220 mesylate Genes associated with Kinase Inhibitor Ro 31-8220 mesylate, curated by the Drug Signature Database ( (more detail) 54 25990557 Homo sapiens
MEX001851
Genes associated with Kinase Inhibitor GW305074X Genes associated with Kinase Inhibitor GW305074X, curated by the Drug Signature Database (DSigDB). (more detail) 54 25990557 Homo sapiens
MEX002381
Genes associated with Kinase Inhibitor Neratinib Genes associated with Kinase Inhibitor Neratinib, curated by the Drug Signature Database (DSigDB). (more detail) 54 25990557 Homo sapiens
TAX001341
Genes annotated by the GO term GO:0004713. Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. (more detail) 63 NA Homo sapiens
MEX001227
Genes associated with Kinase Inhibitor 718630 59 2 Genes associated with Kinase Inhibitor 718630-59-2, curated by the Drug Signature Database (DSigDB). (more detail) 53 25990557 Homo sapiens
WIG001649
Ras Pathway Ras Pathway (more detail) 146 NA Homo sapiens
TAX013666
GO:0001510 biological process RNA methylation Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonu (more detail) 71 NA Homo sapiens
TAX017089
GO:0008146 molecular function sulfotransferase activity Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydro (more detail) 52 NA Homo sapiens
MEX002048
Genes associated with Kinase Inhibitor 1,9 Pyrazoloanthrone Genes associated with Kinase Inhibitor 1,9-Pyrazoloanthrone, curated by the Drug Signature Database (more detail) 52 25990557 Homo sapiens
MOX003562
Genes associated with Computational Drug Signature PONATINIB Genes associated with Computational Drug Signature PONATINIB, curated by the Drug Signature Database (more detail) 59 25990557 Homo sapiens
TAX016371
GO:0006493 biological process protein O linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to (more detail) 100 NA Homo sapiens
TAX015340
GO:0004715 molecular function non membrane spanning protein tyrosine kinase activity Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-me (more detail) 51 NA Homo sapiens
TAX017227
GO:0008375 molecular function acetylglucosaminyltransferase activity Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a suga (more detail) 51 NA Homo sapiens
TAX001439
Genes annotated by the GO term GO:0019199. (more detail) 51 NA Homo sapiens
WIG001490
Estrogen Pathway Estrogen Pathway (more detail) 113 NA Homo sapiens
TAX017226
GO:0008374 molecular function O acyltransferase activity Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule. (more detail) 50 NA Homo sapiens
MEX002421
Genes associated with Kinase Inhibitor Cabozantinib Genes associated with Kinase Inhibitor Cabozantinib, curated by the Drug Signature Database (DSigDB) (more detail) 50 25990557 Homo sapiens
TAX019445
GO:0018022 biological process peptidyl lysine methylation The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative. (more detail) 79 NA Homo sapiens
TAX016355
GO:0006473 biological process protein acetylation The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from ace (more detail) 129 NA Homo sapiens
MEX002401
Genes associated with Kinase Inhibitor Pazopanib Genes associated with Kinase Inhibitor Pazopanib, curated by the Drug Signature Database (DSigDB). (more detail) 49 25990557 Homo sapiens
MEX002248
Genes associated with Kinase Inhibitor Go 6976 Genes associated with Kinase Inhibitor Go 6976, curated by the Drug Signature Database (DSigDB). (more detail) 49 25990557 Homo sapiens
MEX001333
Genes associated with Kinase Inhibitor Staurosporine, N Benzoyl Genes associated with Kinase Inhibitor Staurosporine, N-Benzoyl, curated by the Drug Signature Datab (more detail) 49 25990557 Homo sapiens
MEX001534
Genes associated with Kinase Inhibitor Pazopanib Genes associated with Kinase Inhibitor Pazopanib, curated by the Drug Signature Database (DSigDB). (more detail) 49 25990557 Homo sapiens
MEX001876
Genes associated with Kinase Inhibitor AZD 9291 Genes associated with Kinase Inhibitor AZD-9291, curated by the Drug Signature Database (DSigDB). (more detail) 49 25990557 Homo sapiens
TAX023482
GO:0038083 biological process peptidyl tyrosine autophosphorylation The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosi (more detail) 49 NA Homo sapiens
TAX021011
GO:0031463 cellular component Cul3 RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form (more detail) 71 NA Homo sapiens
TAX001387
Genes annotated by the GO term GO:0008639. Catalysis of the covalent attachment of small proteins, such as ubiquitin or ubiquitin like proteins, to lysine residues on a target protein. This function may be performed alone or in conjunction with an E3, ubiquitin like protein ligase. (more detail) 51 NA Homo sapiens
FEX001656
Leukemia Tavolaro10 56genes Table 3. PK genes highly and specifically expressed in CLL. (more detail) 51 20036005 Homo sapiens
TAX025583
GO:0046467 biological process membrane lipid biosynthetic process The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found i (more detail) 119 NA Homo sapiens
TAX019631
GO:0019205 molecular function nucleobase containing compound kinase activity Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside (more detail) 48 NA Homo sapiens
TAX029196
GO:0070936 biological process protein K48 linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine (more detail) 48 NA Homo sapiens
MEX001296
Genes associated with Kinase Inhibitor Ruboxistaurin Genes associated with Kinase Inhibitor Ruboxistaurin, curated by the Drug Signature Database (DSigDB (more detail) 48 25990557 Homo sapiens
IEI007770
Protein protein interactors of human gene MBP from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MBP (SwissProt ID=P0 (more detail) 80 17535438 Homo sapiens
TAX001383
Genes annotated by the GO term GO:0019787. Catalysis of ATP dependent isopeptide bond formation between the carboxy terminal residues of a small conjugating protein such as ubiquitin or a ubiquitin like protein, and a substrate lysine residue. (more detail) 50 NA Homo sapiens
WAG001218
Glycan structures biosynthesis 2 (more detail) 62 NA Homo sapiens
MEX001248
Genes associated with Kinase Inhibitor Ro 3306 Genes associated with Kinase Inhibitor Ro-3306, curated by the Drug Signature Database (DSigDB). (more detail) 47 25990557 Homo sapiens
MEX001345
Genes associated with Kinase Inhibitor GSK690693 Genes associated with Kinase Inhibitor GSK690693, curated by the Drug Signature Database (DSigDB). (more detail) 47 25990557 Homo sapiens
TAX019447
GO:0018024 molecular function histone lysine N methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + (more detail) 47 NA Homo sapiens
TAX019097
GO:0016571 biological process histone methylation The modification of histones by addition of methyl groups. (more detail) 84 NA Homo sapiens
MEX002045
Genes associated with Kinase Inhibitor Cediranib Genes associated with Kinase Inhibitor Cediranib, curated by the Drug Signature Database (DSigDB). (more detail) 46 25990557 Homo sapiens
TAX018967
GO:0016303 molecular function 1 phosphatidylinositol 3 kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3 (more detail) 46 NA Homo sapiens
WIG000604
Pyrimidine metabolism (more detail) 95 NA Homo sapiens
IEI014597
Protein protein interactors of human gene UBE2W from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2W (SwissProt ID= (more detail) 76 17535438 Homo sapiens
TAX001445
Genes annotated by the GO term GO:0004842. Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N ubiquityllysine. (more detail) 48 NA Homo sapiens
WIG001070
Genes involved in Phase II conjugation (more detail) 69 NA Homo sapiens
MEX001422
Genes associated with Kinase Inhibitor 929095 18 1 Genes associated with Kinase Inhibitor 929095-18-1, curated by the Drug Signature Database (DSigDB). (more detail) 45 25990557 Homo sapiens
MEX001976
Genes associated with Kinase Inhibitor SureCN186278 Genes associated with Kinase Inhibitor SureCN186278, curated by the Drug Signature Database (DSigDB) (more detail) 45 25990557 Homo sapiens
MEX002029
Genes associated with Kinase Inhibitor SU11652 Genes associated with Kinase Inhibitor SU11652, curated by the Drug Signature Database (DSigDB). (more detail) 45 25990557 Homo sapiens
TAX001274
Genes annotated by the GO term GO:0016779. Catalysis of the transfer of a nucleotidyl group to a reactant. (more detail) 47 NA Homo sapiens
WIG000372
MAPKinase Signaling Pathway The ever evolving mitogen-activated protein kinase (MAP kinase) pathways consist of four major group (more detail) 86 NA Homo sapiens
WIG000512
ErbB signaling pathway The ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor l (more detail) 86 NA Homo sapiens
TAX001427
Genes annotated by the GO term GO:0016747. Catalysis of the transfer of an acyl group, other than amino acyl, from one compound (donor) to another (acceptor). (more detail) 49 NA Homo sapiens
MEX001577
Genes associated with Kinase Inhibitor 331771 20 1 Genes associated with Kinase Inhibitor 331771-20-1, curated by the Drug Signature Database (DSigDB). (more detail) 44 25990557 Homo sapiens
MEX002205
Genes associated with Kinase Inhibitor PKR Inhibitor Genes associated with Kinase Inhibitor PKR Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 44 25990557 Homo sapiens
MEX002353
Genes associated with Kinase Inhibitor BRD K72636697 001 01 5 Genes associated with Kinase Inhibitor BRD-K72636697-001-01-5, curated by the Drug Signature Databas (more detail) 44 25990557 Homo sapiens
FEX001679
Leukemia Messina10 53genes Table 3. PK Genes Distinctive of Each ALL Subgroup (more detail) 46 20564080 Homo sapiens
MEX000882
Genes associated with Approved Drug nilotinib Genes associated with Approved Drug nilotinib, curated by the Drug Signature Database (DSigDB). (more detail) 65 25990557 Homo sapiens
TAX001065
Genes annotated by the GO term GO:0016881. Catalysis of the ligation of an acid to an amino acid via a carbon nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. (more detail) 56 NA Homo sapiens
TAX019531
GO:0018394 biological process peptidyl lysine acetylation The acetylation of peptidyl-lysine. (more detail) 110 NA Homo sapiens
TAX001441
Genes annotated by the GO term GO:0004714. Catalysis of the reaction: ATP + a protein L tyrosine = ADP + a protein L tyrosine phosphate, to initiate a change in cell activity. (more detail) 43 NA Homo sapiens
MEX001367
Genes associated with Kinase Inhibitor Linifanib Genes associated with Kinase Inhibitor Linifanib, curated by the Drug Signature Database (DSigDB). (more detail) 43 25990557 Homo sapiens
MEX002405
Genes associated with Kinase Inhibitor Vemurafenib Genes associated with Kinase Inhibitor Vemurafenib, curated by the Drug Signature Database (DSigDB). (more detail) 43 25990557 Homo sapiens
FEX000743
Breast Speers09 52genes OverExpressedNegativeCancer Supplementary Table 2: Kinases overexpressed in ER?negative breast cancer (more detail) 51 19808870 Homo sapiens
TAX022291
GO:0034061 molecular function DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synth (more detail) 42 NA Homo sapiens
TAX015337
GO:0004712 molecular function protein serine/threonine/tyrosine kinase activity Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein (more detail) 42 NA Homo sapiens
MEX002372
Genes associated with Kinase Inhibitor Sorafenib Genes associated with Kinase Inhibitor Sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 42 25990557 Homo sapiens
MEX001977
Genes associated with Kinase Inhibitor MLN8054 Genes associated with Kinase Inhibitor MLN8054, curated by the Drug Signature Database (DSigDB). (more detail) 42 25990557 Homo sapiens
WAG001226
ErbB signaling pathway The ErbB family of receptor tyrosine kises (RTKs) couples binding of extracellular growth factor lig (more detail) 75 NA Homo sapiens
TAX016079
GO:0006023 biological process aminoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containi (more detail) 102 NA Homo sapiens
FEX000745
Breast Speers09 52genes IDKinasesOverExpressed Table 2. Kinases identified in analysis as most highly overexpressed in ER-negative tumors (more detail) 50 19808870 Homo sapiens
TAX030991
GO:0097747 molecular function RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis (more detail) 41 NA Homo sapiens
TAX022292
GO:0034062 molecular function 5' 3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis (more detail) 41 NA Homo sapiens
TAX019208
GO:0016776 molecular function phosphotransferase activity, phosphate group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate (more detail) 41 NA Homo sapiens
MEX001356
Genes associated with Kinase Inhibitor Vemurafenib Genes associated with Kinase Inhibitor Vemurafenib, curated by the Drug Signature Database (DSigDB). (more detail) 41 25990557 Homo sapiens
MEX001533
Genes associated with Kinase Inhibitor SureCN3470757 Genes associated with Kinase Inhibitor SureCN3470757, curated by the Drug Signature Database (DSigDB (more detail) 41 25990557 Homo sapiens
MEX002347
Genes associated with Kinase Inhibitor 918505 84 7 Genes associated with Kinase Inhibitor 918505-84-7, curated by the Drug Signature Database (DSigDB). (more detail) 41 25990557 Homo sapiens
MEX002058
Genes associated with Kinase Inhibitor indirubin deriv. 7a Genes associated with Kinase Inhibitor indirubin deriv. 7a, curated by the Drug Signature Database ( (more detail) 41 25990557 Homo sapiens
TAX001446
Genes annotated by the GO term GO:0008194. Catalysis of the transfer of a glycosyl group from a UDP sugar to a small hydrophobic molecule. (more detail) 41 NA Homo sapiens
MEX002155
Genes associated with Kinase Inhibitor AGN PC 04XSIT Genes associated with Kinase Inhibitor AGN-PC-04XSIT, curated by the Drug Signature Database (DSigDB (more detail) 43 25990557 Homo sapiens
TAX023250
GO:0036092 biological process phosphatidylinositol 3 phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, (more detail) 53 NA Homo sapiens
MEX001905
Genes associated with Kinase Inhibitor Axitinib Genes associated with Kinase Inhibitor Axitinib, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens
MEX002356
Genes associated with Kinase Inhibitor Dinaciclib Genes associated with Kinase Inhibitor Dinaciclib, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens
MEX002404
Genes associated with Kinase Inhibitor Axitinib Genes associated with Kinase Inhibitor Axitinib, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens
MEX001834
Genes associated with Kinase Inhibitor 722544 51 6 Genes associated with Kinase Inhibitor 722544-51-6, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens
MEX002035
Genes associated with Kinase Inhibitor GSK1838705A Genes associated with Kinase Inhibitor GSK1838705A, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens
MEX001839
Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 39 25990557 Homo sapiens
TAX001228
Genes annotated by the GO term GO:0016879. Catalysis of the ligation of two substances via a carbon nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. (more detail) 65 NA Homo sapiens
WIG000934
Genes involved in Insulin receptor signalling cascade (more detail) 85 NA Homo sapiens
MEX001100
Genes associated with Approved Drug afatinib Genes associated with Approved Drug afatinib, curated by the Drug Signature Database (DSigDB). (more detail) 38 25990557 Homo sapiens
TAX014838
GO:0003899 molecular function DNA directed 5' 3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA (more detail) 38 NA Homo sapiens
MEX001769
Genes associated with Kinase Inhibitor GSK2606414 Genes associated with Kinase Inhibitor GSK2606414, curated by the Drug Signature Database (DSigDB). (more detail) 38 25990557 Homo sapiens
MEX002420
Genes associated with Kinase Inhibitor Nilotinib Genes associated with Kinase Inhibitor Nilotinib, curated by the Drug Signature Database (DSigDB). (more detail) 38 25990557 Homo sapiens
TAX030871
GO:0097472 molecular function cyclin dependent protein kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the rea (more detail) 38 NA Homo sapiens
TAX019003
GO:0016409 molecular function palmitoyltransferase activity Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule. (more detail) 38 NA Homo sapiens
TAX028981
GO:0070534 biological process protein K63 linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine (more detail) 38 NA Homo sapiens
WIG001076
Genes involved in PI3K Cascade (more detail) 69 NA Homo sapiens
TAX001238
Genes annotated by the GO term GO:0000287. Interacting selectively with magnesium (Mg) ions. (more detail) 59 NA Homo sapiens
TAX017628
GO:0009247 biological process glycolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-ac (more detail) 57 NA Homo sapiens
TAX022673
GO:0034968 biological process histone lysine methylation The modification of a histone by addition of one or more methyl groups to a lysine residue. (more detail) 65 NA Homo sapiens
MEX001785
Genes associated with Kinase Inhibitor Kinome 1194 Genes associated with Kinase Inhibitor Kinome_1194, curated by the Drug Signature Database (DSigDB). (more detail) 37 25990557 Homo sapiens
TAX015324
GO:0004693 molecular function cyclin dependent protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein (more detail) 37 NA Homo sapiens
MEX002186
Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 37 25990557 Homo sapiens
MEX001320
Genes associated with Kinase Inhibitor IKK Inhibitor VII Genes associated with Kinase Inhibitor IKK Inhibitor VII, curated by the Drug Signature Database (DS (more detail) 37 25990557 Homo sapiens
MEX002100
Genes associated with Kinase Inhibitor Nilotinib Genes associated with Kinase Inhibitor Nilotinib, curated by the Drug Signature Database (DSigDB). (more detail) 37 25990557 Homo sapiens
IEI014572
Protein protein interactors of human gene UBE2E2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2E2 (SwissProt ID (more detail) 80 17535438 Homo sapiens
MEX001590
Genes associated with Kinase Inhibitor BMS 387032 Genes associated with Kinase Inhibitor BMS-387032, curated by the Drug Signature Database (DSigDB). (more detail) 36 25990557 Homo sapiens
TAX015090
GO:0004364 molecular function glutathione transferase activity Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromati (more detail) 36 NA Homo sapiens
MEX001454
Genes associated with Kinase Inhibitor Quercetagetin Genes associated with Kinase Inhibitor Quercetagetin, curated by the Drug Signature Database (DSigDB (more detail) 36 25990557 Homo sapiens
MEX001723
Genes associated with Kinase Inhibitor SureCN10127740 Genes associated with Kinase Inhibitor SureCN10127740, curated by the Drug Signature Database (DSigD (more detail) 36 25990557 Homo sapiens
TAX001429
Genes annotated by the GO term GO:0016741. Catalysis of the transfer of a one carbon group from one compound (donor) to another (acceptor). (more detail) 36 NA Homo sapiens
FOX000529
Genes in the cancer module 199 (more detail) 57 NA Homo sapiens
WIG001729
Yersinia Infection Yersinia Infection (more detail) 79 NA Homo sapiens
MEX002063
Genes associated with Kinase Inhibitor Erlotinib Genes associated with Kinase Inhibitor Erlotinib, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens
MEX001696
Genes associated with Kinase Inhibitor Ki20227 Genes associated with Kinase Inhibitor Ki20227, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens
MEX002398
Genes associated with Kinase Inhibitor Erlotinib Genes associated with Kinase Inhibitor Erlotinib, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens
MEX001485
Genes associated with Kinase Inhibitor Syk Inhibitor Genes associated with Kinase Inhibitor Syk Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 35 25990557 Homo sapiens
TAX001247
Genes annotated by the GO term GO:0008168. Catalysis of the transfer of a methyl group to an acceptor molecule. (more detail) 35 NA Homo sapiens
MEX002385
Genes associated with Kinase Inhibitor R547 Genes associated with Kinase Inhibitor R547, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens
MEX002126
Genes associated with Kinase Inhibitor 841290 80 0 Genes associated with Kinase Inhibitor 841290-80-0, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens
MEX001512
Genes associated with Kinase Inhibitor Doramapimod Genes associated with Kinase Inhibitor Doramapimod, curated by the Drug Signature Database (DSigDB). (more detail) 35 25990557 Homo sapiens
TAX017229
GO:0008378 molecular function galactosyltransferase activity Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydr (more detail) 35 NA Homo sapiens
WIG000560
Melanoma Five distinct stages have been proposed in the evolution of melanoma on the basis of histological cr (more detail) 71 NA Homo sapiens
WIG001504
FGF Pathway FGF Pathway (more detail) 77 NA Homo sapiens
TAX018441
GO:0015020 molecular function glucuronosyltransferase activity Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. (more detail) 34 NA Homo sapiens
MEX002394
Genes associated with Kinase Inhibitor TG100 115 Genes associated with Kinase Inhibitor TG100-115, curated by the Drug Signature Database (DSigDB). (more detail) 34 25990557 Homo sapiens
MEX001554
Genes associated with Kinase Inhibitor TAK 715 Genes associated with Kinase Inhibitor TAK-715, curated by the Drug Signature Database (DSigDB). (more detail) 34 25990557 Homo sapiens
TAX017228
GO:0008376 molecular function acetylgalactosaminyltransferase activity Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an (more detail) 34 NA Homo sapiens
TAX030039
GO:0072528 biological process pyrimidine containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, (more detail) 54 NA Homo sapiens
MEX002298
Genes associated with Kinase Inhibitor IPA 3 Genes associated with Kinase Inhibitor IPA-3, curated by the Drug Signature Database (DSigDB). (more detail) 33 25990557 Homo sapiens
MEX002418
Genes associated with Kinase Inhibitor Regorafenib Genes associated with Kinase Inhibitor Regorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 33 25990557 Homo sapiens
TAX001352
Genes annotated by the GO term GO:0004702. (more detail) 33 NA Homo sapiens
TAX030893
GO:0097502 biological process mannosylation The covalent attachment of a mannose residue to a substrate molecule. (more detail) 33 NA Homo sapiens
WAG001431
Melanoma Melanoma is a form of skin cancer that has a poor prognosis and which is on the rise in Western popu (more detail) 65 NA Homo sapiens
TAX016366
GO:0006487 biological process protein N linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to (more detail) 65 NA Homo sapiens
MEX001278
Genes associated with Kinase Inhibitor AGN PC 0INJ9Y Genes associated with Kinase Inhibitor AGN-PC-0INJ9Y, curated by the Drug Signature Database (DSigDB (more detail) 32 25990557 Homo sapiens
MEX002328
Genes associated with Kinase Inhibitor SureCN571763 Genes associated with Kinase Inhibitor SureCN571763, curated by the Drug Signature Database (DSigDB) (more detail) 32 25990557 Homo sapiens
MEX001438
Genes associated with Kinase Inhibitor Ro 3306 Genes associated with Kinase Inhibitor Ro-3306, curated by the Drug Signature Database (DSigDB). (more detail) 32 25990557 Homo sapiens
TAX001432
Genes annotated by the GO term GO:0016782. Catalysis of the transfer of a sulfur containing group from one compound (donor) to another (acceptor). (more detail) 32 NA Homo sapiens
IEI014594
Protein protein interactors of human gene UBE2U from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2U (SwissProt ID= (more detail) 67 17535438 Homo sapiens
WEX000061
Melanoma The genes related to melanoma (physiology & disease) in tumor using next-generation sequencer (NGS) (more detail) 70 NA Homo sapiens
TAX016383
GO:0006513 biological process protein monoubiquitination Addition of a single ubiquitin group to a protein. (more detail) 60 NA Homo sapiens
WIG001485
ErbB Family Pathway ErbB Family Pathway (more detail) 63 NA Homo sapiens
TAX019011
GO:0016417 molecular function S acyltransferase activity Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule. (more detail) 31 NA Homo sapiens
MEX002019
Genes associated with Kinase Inhibitor Canertinib Genes associated with Kinase Inhibitor Canertinib, curated by the Drug Signature Database (DSigDB). (more detail) 31 25990557 Homo sapiens
MEX001223
Genes associated with Kinase Inhibitor NVP TAE684 Genes associated with Kinase Inhibitor NVP-TAE684, curated by the Drug Signature Database (DSigDB). (more detail) 31 25990557 Homo sapiens
MEX001412
Genes associated with Kinase Inhibitor Tyrphostin AG 1478 Genes associated with Kinase Inhibitor Tyrphostin AG 1478, curated by the Drug Signature Database (D (more detail) 31 25990557 Homo sapiens
TAX000334
Genes annotated by the GO term GO:0046467. The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane. (more detail) 48 NA Homo sapiens
TAX016196
GO:0006221 biological process pyrimidine nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compoun (more detail) 44 NA Homo sapiens
MEX001395
Genes associated with Kinase Inhibitor Indirubin Derivative E804 Genes associated with Kinase Inhibitor Indirubin Derivative E804, curated by the Drug Signature Data (more detail) 30 25990557 Homo sapiens
MEX001409
Genes associated with Kinase Inhibitor PP242 Genes associated with Kinase Inhibitor PP242, curated by the Drug Signature Database (DSigDB). (more detail) 30 25990557 Homo sapiens
MEX002386
Genes associated with Kinase Inhibitor GW843682X Genes associated with Kinase Inhibitor GW843682X, curated by the Drug Signature Database (DSigDB). (more detail) 30 25990557 Homo sapiens
MEX001663
Genes associated with Kinase Inhibitor RAF265 Genes associated with Kinase Inhibitor RAF265, curated by the Drug Signature Database (DSigDB). (more detail) 30 25990557 Homo sapiens
TAX001425
Genes annotated by the GO term GO:0016765. Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor). (more detail) 30 NA Homo sapiens
MEX001287
Genes associated with Kinase Inhibitor BI 2536 Genes associated with Kinase Inhibitor BI 2536, curated by the Drug Signature Database (DSigDB). (more detail) 30 25990557 Homo sapiens
MEX002110
Genes associated with Kinase Inhibitor AGN PC 0HSSYL Genes associated with Kinase Inhibitor AGN-PC-0HSSYL, curated by the Drug Signature Database (DSigDB (more detail) 30 25990557 Homo sapiens
TAX028527
GO:0061650 molecular function ubiquitin like protein conjugating enzyme activity Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction (more detail) 30 NA Homo sapiens
TAX022779
GO:0035250 molecular function UDP galactosyltransferase activity Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule. (more detail) 30 NA Homo sapiens
WIG001413
VEGF Signaling Pathway Model endothelial cell displaying genes of the VEGF signalling pathway and the sites at which bevaci (more detail) 55 NA Homo sapiens
TAX019005
GO:0016411 molecular function acylglycerol O acyltransferase activity Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule. (more detail) 29 NA Homo sapiens
TAX017105
GO:0008175 molecular function tRNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule. (more detail) 29 NA Homo sapiens
MEX002239
Genes associated with Kinase Inhibitor Kinome 635 Genes associated with Kinase Inhibitor Kinome_635, curated by the Drug Signature Database (DSigDB). (more detail) 29 25990557 Homo sapiens
MEX002250
Genes associated with Kinase Inhibitor BI D1870 Genes associated with Kinase Inhibitor BI-D1870, curated by the Drug Signature Database (DSigDB). (more detail) 29 25990557 Homo sapiens
MEX001623
Genes associated with Kinase Inhibitor AT7519 Genes associated with Kinase Inhibitor AT7519, curated by the Drug Signature Database (DSigDB). (more detail) 29 25990557 Homo sapiens
MEX001589
Genes associated with Kinase Inhibitor dorsomorphin Genes associated with Kinase Inhibitor dorsomorphin, curated by the Drug Signature Database (DSigDB) (more detail) 29 25990557 Homo sapiens
PEX001905
UQ con: Ubiquitin conjugating enzyme Proteins destined for proteasome-mediated degradation may be ubiquitinated. Ubiquitination follows c (more detail) 29 NA Homo sapiens
MEX001410
Genes associated with Kinase Inhibitor NG25 Genes associated with Kinase Inhibitor NG25, curated by the Drug Signature Database (DSigDB). (more detail) 29 25990557 Homo sapiens
MEX002028
Genes associated with Kinase Inhibitor CHEMBL1673039 Genes associated with Kinase Inhibitor CHEMBL1673039, curated by the Drug Signature Database (DSigDB (more detail) 29 25990557 Homo sapiens
FOX000843
Genes in the cancer module 85 (more detail) 51 NA Homo sapiens
WAG001630
N Glycan biosynthesis N-glycans or asparagine-linked glycans are major constituents of glycoproteins in eukaryotes. N-glyc (more detail) 46 NA Homo sapiens
TAX018946
GO:0016266 biological process O glycan processing The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-l (more detail) 60 NA Homo sapiens
MOX012175
Genes associated with Computational Drug Signature Dasatinib Genes associated with Computational Drug Signature Dasatinib, curated by the Drug Signature Database (more detail) 50 25990557 Homo sapiens
TAX028519
GO:0061631 molecular function ubiquitin conjugating enzyme activity Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y (more detail) 28 NA Homo sapiens
MEX001110
Genes associated with Approved Drug pazopanib hydrochloride Genes associated with Approved Drug pazopanib hydrochloride, curated by the Drug Signature Database (more detail) 28 25990557 Homo sapiens
MEX001704
Genes associated with Kinase Inhibitor ITK inhibitor Genes associated with Kinase Inhibitor ITK inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 28 25990557 Homo sapiens
MEX002007
Genes associated with Kinase Inhibitor GSK 650394 Genes associated with Kinase Inhibitor GSK 650394, curated by the Drug Signature Database (DSigDB). (more detail) 28 25990557 Homo sapiens
WIG000615
RNA polymerase (more detail) 28 NA Homo sapiens
TAX001408
Genes annotated by the GO term GO:0008146. Catalysis of the transfer of a sulfate group from 3' phosphoadenosine 5' phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3' phosphoadenosine 5' phosphate. (more detail) 28 NA Homo sapiens
TAX015317
GO:0004683 molecular function calmodulin dependent protein kinase activity Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a pro (more detail) 28 NA Homo sapiens
MEX001261
Genes associated with Kinase Inhibitor Torin 1 Genes associated with Kinase Inhibitor Torin 1, curated by the Drug Signature Database (DSigDB). (more detail) 28 25990557 Homo sapiens
WIG001487
ErbB4 Pathway ErbB4 Pathway (more detail) 51 NA Homo sapiens
WIG001080
Genes involved in PI 3K cascade (more detail) 54 NA Homo sapiens
FOX000584
Genes in the cancer module 259 (more detail) 46 NA Homo sapiens
WIG000574
N Glycan biosynthesis N-glycans or asparagine-linked glycans are major constituents of glycoproteins in eukaryotes. N-glyc (more detail) 46 NA Homo sapiens
MEX002246
Genes associated with Kinase Inhibitor Bosutinib Genes associated with Kinase Inhibitor Bosutinib, curated by the Drug Signature Database (DSigDB). (more detail) 27 25990557 Homo sapiens
MEX001642
Genes associated with Kinase Inhibitor AGN PC 04T5ZK Genes associated with Kinase Inhibitor AGN-PC-04T5ZK, curated by the Drug Signature Database (DSigDB (more detail) 27 25990557 Homo sapiens
MEX001616
Genes associated with Kinase Inhibitor AGN PC 087NKJ Genes associated with Kinase Inhibitor AGN-PC-087NKJ, curated by the Drug Signature Database (DSigDB (more detail) 27 25990557 Homo sapiens
TAX014836
GO:0003887 molecular function DNA directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synth (more detail) 27 NA Homo sapiens
TAX019782
GO:0019706 molecular function protein cysteine S palmitoyltransferase activity Catalysis of the transfer of a palmitoyl group to a sulfur atom on the cysteine of a protein molecul (more detail) 27 NA Homo sapiens
TAX019783
GO:0019707 molecular function protein cysteine S acyltransferase activity Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule. (more detail) 27 NA Homo sapiens
TAX020687
GO:0030880 cellular component RNA polymerase complex Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one (more detail) 55 NA Homo sapiens
TAX000065
Genes annotated by the GO term GO:0016051. The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. (more detail) 47 NA Homo sapiens
MOX007315
Genes associated with Computational Drug Signature bisindolylmaleimide iv Genes associated with Computational Drug Signature bisindolylmaleimide iv, curated by the Drug Signa (more detail) 29 25990557 Homo sapiens
WIG000138
p53 pathway (more detail) 56 NA Homo sapiens
TAX019510
GO:0018279 biological process protein N linked glycosylation via asparagine The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine (more detail) 38 NA Homo sapiens
TAX000093
Genes annotated by the GO term GO:0044257. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. (more detail) 54 NA Homo sapiens
TAX029006
GO:0070566 molecular function adenylyltransferase activity Catalysis of the transfer of an adenylyl group to an acceptor. (more detail) 26 NA Homo sapiens
MEX002195
Genes associated with Kinase Inhibitor BX 912 Genes associated with Kinase Inhibitor BX-912, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens
WIG000580
O Glycan biosynthesis O-glycans are a class of glycans that modify serine or threonine residues of proteins. Biosynthesis (more detail) 26 NA Homo sapiens
MEX002158
Genes associated with Kinase Inhibitor Enzastaurin Genes associated with Kinase Inhibitor Enzastaurin, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens
TAX015335
GO:0004709 molecular function MAP kinase kinase kinase activity Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can b (more detail) 26 NA Homo sapiens
MEX002214
Genes associated with Kinase Inhibitor 3ztx Genes associated with Kinase Inhibitor 3ztx, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens
MEX002192
Genes associated with Kinase Inhibitor ILORASERTIB Genes associated with Kinase Inhibitor ILORASERTIB, curated by the Drug Signature Database (DSigDB). (more detail) 26 25990557 Homo sapiens
TAX014869
GO:0003950 molecular function NAD+ ADP ribosyltransferase activity Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)- (more detail) 26 NA Homo sapiens
FOX000621
Genes in the cancer module 303 (more detail) 28 NA Homo sapiens
WIG001051
Genes involved in O linked glycosylation of mucins (more detail) 52 NA Homo sapiens
TAX020524
GO:0030488 biological process tRNA methylation The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. (more detail) 32 NA Homo sapiens
TAX019485
GO:0018196 biological process peptidyl asparagine modification The modification of peptidyl-asparagine. (more detail) 39 NA Homo sapiens
TAX000570
Genes annotated by the GO term GO:0016567. The process by which one or more ubiquitin moieties are added to a protein. (more detail) 39 NA Homo sapiens
IEI014583
Protein protein interactors of human gene UBE2L6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2L6 (SwissProt ID (more detail) 47 17535438 Homo sapiens
TAX013337
GO:0000271 biological process polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of man (more detail) 37 NA Homo sapiens
TAX013410
GO:0000428 cellular component DNA directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity. (more detail) 53 NA Homo sapiens
WIG001205
Genes involved in Signaling by FGFR mutants (more detail) 42 NA Homo sapiens
TAX000556
Genes annotated by the GO term GO:0032446. A process by which one or more moieties of a small protein, such as ubiquitin or a ubiquitin like protein, are covalently attached to a target protein. (more detail) 42 NA Homo sapiens
WIG001971
Eukaryotic Transcription Initiation Eukaryotic Transcription Initiation (more detail) 42 NA Homo sapiens
TAX026415
GO:0050145 molecular function nucleoside monophosphate kinase activity Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate. (more detail) 25 NA Homo sapiens
MEX001658
Genes associated with Kinase Inhibitor GW768505A Genes associated with Kinase Inhibitor GW768505A, curated by the Drug Signature Database (DSigDB). (more detail) 25 25990557 Homo sapiens
MEX002062
Genes associated with Kinase Inhibitor Crenolanib Genes associated with Kinase Inhibitor Crenolanib, curated by the Drug Signature Database (DSigDB). (more detail) 25 25990557 Homo sapiens
TAX013221
GO:0000030 molecular function mannosyltransferase activity Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrat (more detail) 25 NA Homo sapiens
WIG000534
Glycosphingolipid biosynthesis lacto and neolacto series (more detail) 25 NA Homo sapiens
TAX027542
GO:0055029 cellular component nuclear DNA directed RNA polymerase complex A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity. (more detail) 52 NA Homo sapiens
WIG000850
Genes involved in FRS2 mediated cascade (more detail) 36 NA Homo sapiens
TAX019816
GO:0019789 molecular function SUMO transferase activity Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO (more detail) 24 NA Homo sapiens
TAX025761
GO:0046835 biological process carbohydrate phosphorylation The process of introducing a phosphate group into a carbohydrate, any organic compound based on the (more detail) 24 NA Homo sapiens
MEX002337
Genes associated with Kinase Inhibitor su6656 Genes associated with Kinase Inhibitor su6656, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens
WAG000206
O Glycan biosynthesis O-glycans are a class of glycans that modify serine or threonine residues of proteins. Biosynthesis (more detail) 24 NA Homo sapiens
MEX001309
Genes associated with Kinase Inhibitor CHEMBL552425 Genes associated with Kinase Inhibitor CHEMBL552425, curated by the Drug Signature Database (DSigDB) (more detail) 24 25990557 Homo sapiens
MEX001794
Genes associated with Kinase Inhibitor MLN8054 Genes associated with Kinase Inhibitor MLN8054, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens
MEX001535
Genes associated with Kinase Inhibitor go 7874 Genes associated with Kinase Inhibitor go 7874, curated by the Drug Signature Database (DSigDB). (more detail) 24 25990557 Homo sapiens
MEX002139
Genes associated with Kinase Inhibitor JAK Inhibitor I Genes associated with Kinase Inhibitor JAK Inhibitor I, curated by the Drug Signature Database (DSig (more detail) 24 25990557 Homo sapiens
MAX000764
Genes required for CTNNB1 [GeneID=1499] activity in DLD 1 cell (colon cancer with APC [GeneID=324] deletions), based on shRNA screen. Aberrant activation of the canonical WNT/beta-catenin pathway occurs in almost all colorectal cancer (more detail) 32 NA Homo sapiens
TAX000535
Genes annotated by the GO term GO:0046777. The phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. (more detail) 30 NA Homo sapiens
TAX020848
GO:0031167 biological process rRNA methylation The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule. (more detail) 26 NA Homo sapiens
WIG000529
Glycosaminoglycan biosynthesis heparan sulfate (more detail) 26 NA Homo sapiens
WIG001014
Genes involved in Negative regulation of FGFR signaling (more detail) 37 NA Homo sapiens
TAX019098
GO:0016572 biological process histone phosphorylation The modification of histones by addition of phosphate groups. (more detail) 28 NA Homo sapiens
TAX022216
GO:0033692 biological process cellular polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (more detail) 35 NA Homo sapiens
MEX002221
Genes associated with Kinase Inhibitor Sunitinib Genes associated with Kinase Inhibitor Sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens
TAX019203
GO:0016769 molecular function transferase activity, transferring nitrogenous groups Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor). (more detail) 23 NA Homo sapiens
MEX001418
Genes associated with Kinase Inhibitor TSU 68 Genes associated with Kinase Inhibitor TSU-68, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens
MAX003001
Genes whose expression most significantly correlated with cancer cell line sensitivity to the proapoptotic ligand APO2 [GeneID=8797] . Apo2L/TRAIL stimulates cancer cell death through the proapoptotic receptors DR4 and DR5, but the det (more detail) 23 NA Homo sapiens
MEX002206
Genes associated with Kinase Inhibitor BI 2536 Genes associated with Kinase Inhibitor BI 2536, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens
MEX002057
Genes associated with Kinase Inhibitor Kinome 800 Genes associated with Kinase Inhibitor Kinome_800, curated by the Drug Signature Database (DSigDB). (more detail) 23 25990557 Homo sapiens
TAX017101
GO:0008171 molecular function O methyltransferase activity Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule. (more detail) 23 NA Homo sapiens
TAX031709
GO:0140103 molecular function catalytic activity, acting on a glycoprotein catalytic activity, acting on a glycosylated protein (more detail) 23 NA Homo sapiens
TAX000541
Genes annotated by the GO term GO:0016540. Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein. (more detail) 31 NA Homo sapiens
WIG000735
Genes involved in CD28 co stimulation (more detail) 31 NA Homo sapiens
TAX001064
Genes annotated by the GO term GO:0016407. Catalysis of the transfer of an acetyl group to an acceptor molecule. (more detail) 25 NA Homo sapiens
TAX000811
Genes annotated by the GO term GO:0006512. The cyclical process by which one or more ubiquitin moieties are added to (ubiquitination) and removed from (deubiquitination) a protein. (more detail) 47 NA Homo sapiens
TAX017560
GO:0009163 biological process nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any one of a family of organic mol (more detail) 47 NA Homo sapiens
TAX000467
Genes annotated by the GO term GO:0008654. The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono or diester. (more detail) 39 NA Homo sapiens
TAX019628
GO:0019200 molecular function carbohydrate kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecu (more detail) 22 NA Homo sapiens
MEX002410
Genes associated with Kinase Inhibitor Gefitinib Genes associated with Kinase Inhibitor Gefitinib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens
TAX001411
Genes annotated by the GO term GO:0008757. Catalysis of the transfer of a methyl group from S adenosyl L methionine to a substrate. (more detail) 22 NA Homo sapiens
MEX001455
Genes associated with Kinase Inhibitor CHEMBL468963 Genes associated with Kinase Inhibitor CHEMBL468963, curated by the Drug Signature Database (DSigDB) (more detail) 22 25990557 Homo sapiens
WIG000841
Genes involved in FGFR ligand binding and activation (more detail) 22 NA Homo sapiens
MEX001895
Genes associated with Kinase Inhibitor Motesanib Genes associated with Kinase Inhibitor Motesanib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens
PEX000769
SET: SET domain SET domains are protein lysine methyltransferase enzymes. SET domains appear to be protein-protein i (more detail) 22 NA Homo sapiens
MEX001434
Genes associated with Kinase Inhibitor Brivanib Genes associated with Kinase Inhibitor Brivanib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens
MEX001537
Genes associated with Kinase Inhibitor NCGC00346967 01 Genes associated with Kinase Inhibitor NCGC00346967-01, curated by the Drug Signature Database (DSig (more detail) 22 25990557 Homo sapiens
MEX001859
Genes associated with Kinase Inhibitor 405169 16 6 Genes associated with Kinase Inhibitor 405169-16-6, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens
MEX001613
Genes associated with Kinase Inhibitor CHEMBL1241473 Genes associated with Kinase Inhibitor CHEMBL1241473, curated by the Drug Signature Database (DSigDB (more detail) 22 25990557 Homo sapiens
MEX001956
Genes associated with Kinase Inhibitor 844499 71 4 Genes associated with Kinase Inhibitor 844499-71-4, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens
MEX001396
Genes associated with Kinase Inhibitor Gefitinib Genes associated with Kinase Inhibitor Gefitinib, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens
MEX001972
Genes associated with Kinase Inhibitor 722544 51 6 Genes associated with Kinase Inhibitor 722544-51-6, curated by the Drug Signature Database (DSigDB). (more detail) 22 25990557 Homo sapiens
TAX016530
GO:0006688 biological process glycosphingolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with (more detail) 22 NA Homo sapiens
TAX001276
Genes annotated by the GO term GO:0016410. Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule. (more detail) 24 NA Homo sapiens
TAX025614
GO:0046513 biological process ceramide biosynthetic process The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoi (more detail) 41 NA Homo sapiens
TAX031708
GO:0140102 molecular function catalytic activity, acting on a rRNA Catalytic activity that acts to modify a ribosomal RNA. (more detail) 21 NA Homo sapiens
TAX017300
GO:0008483 molecular function transaminase activity Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid. (more detail) 21 NA Homo sapiens
MEX002324
Genes associated with Kinase Inhibitor CHEMBL1967116 Genes associated with Kinase Inhibitor CHEMBL1967116, curated by the Drug Signature Database (DSigDB (more detail) 21 25990557 Homo sapiens
MEX001652
Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens
MEX002120
Genes associated with Kinase Inhibitor GW559768X Genes associated with Kinase Inhibitor GW559768X, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens
TAX017389
GO:0008649 molecular function rRNA methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in (more detail) 21 NA Homo sapiens
MAX000760
Genes in the blue cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. Breast cancer is a heterogeneous disease made of various molecular subtypes with different prognosis (more detail) 21 NA Homo sapiens
TAX022794
GO:0035268 biological process protein mannosylation The addition of a mannose residue to a protein acceptor molecule. (more detail) 21 NA Homo sapiens
MEX001818
Genes associated with Kinase Inhibitor TPCA 1 Genes associated with Kinase Inhibitor TPCA-1, curated by the Drug Signature Database (DSigDB). (more detail) 21 25990557 Homo sapiens
WAG000808
RNA polymerase (more detail) 21 NA Homo sapiens
WIG001386
Sorafenib Pharmacodynamics Mechanism of action of sorafenib (more detail) 27 NA Homo sapiens
TAX016354
GO:0006471 biological process protein ADP ribosylation The transfer, from NAD, of ADP-ribose to protein amino acids. (more detail) 25 NA Homo sapiens
TAX001270
Genes annotated by the GO term GO:0019205. Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate. (more detail) 25 NA Homo sapiens
WAG000723
RNA Pol II CTD phosphorylation and interaction with CE (more detail) 25 NA Homo sapiens
WAG000313
RNA Pol II CTD phosphorylation and interaction with CE (more detail) 25 NA Homo sapiens
TAX023850
GO:0042455 biological process ribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside i (more detail) 40 NA Homo sapiens
WIG000916
Genes involved in Interleukin 2 signaling (more detail) 41 NA Homo sapiens
TAX023310
GO:0036260 biological process RNA capping The sequence of enzymatic reactions by which a cap structure is added to the 5' end of a nascent RNA (more detail) 33 NA Homo sapiens
TAX017706
GO:0009452 biological process 7 methylguanosine RNA capping The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine lin (more detail) 33 NA Homo sapiens
TAX023709
GO:0042171 molecular function lysophosphatidic acid acyltransferase activity Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphati (more detail) 20 NA Homo sapiens
TAX019002
GO:0016408 molecular function C acyltransferase activity Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule. (more detail) 20 NA Homo sapiens
TAX030894
GO:0097503 biological process sialylation The covalent attachment of sialic acid to a substrate molecule. (more detail) 20 NA Homo sapiens
TAX029571
GO:0071617 molecular function lysophospholipid acyltransferase activity Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid. (more detail) 20 NA Homo sapiens
MEX001585
Genes associated with Kinase Inhibitor NCGC00346963 01 Genes associated with Kinase Inhibitor NCGC00346963-01, curated by the Drug Signature Database (DSig (more detail) 20 25990557 Homo sapiens
MEX002422
Genes associated with Kinase Inhibitor Lenvatinib Genes associated with Kinase Inhibitor Lenvatinib, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens
MEX001882
Genes associated with Kinase Inhibitor 918505 84 7 Genes associated with Kinase Inhibitor 918505-84-7, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens
TAX014808
GO:0003841 molecular function 1 acylglycerol 3 phosphate O acyltransferase activity Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol- (more detail) 20 NA Homo sapiens
MEX001726
Genes associated with Kinase Inhibitor GSK1007102B Genes associated with Kinase Inhibitor GSK1007102B, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens
MEX001484
Genes associated with Kinase Inhibitor Kinome 511 Genes associated with Kinase Inhibitor Kinome_511, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens
MEX001606
Genes associated with Kinase Inhibitor Lck Inhibitor Genes associated with Kinase Inhibitor Lck Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 20 25990557 Homo sapiens
TAX001430
Genes annotated by the GO term GO:0016763. Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). (more detail) 20 NA Homo sapiens
TAX017225
GO:0008373 molecular function sialyltransferase activity Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of (more detail) 20 NA Homo sapiens
MEX001208
Genes associated with Kinase Inhibitor gw5074 Genes associated with Kinase Inhibitor gw5074, curated by the Drug Signature Database (DSigDB). (more detail) 20 25990557 Homo sapiens
FOX000840
Genes in the cancer module 82 (more detail) 24 NA Homo sapiens
WIG000528
Glycosaminoglycan biosynthesis chondroitin sulfate Glycosaminoglycans (GAGs) are linear polysaccharide chains consisting of repeating disaccharide unit (more detail) 22 NA Homo sapiens
FOX000576
Genes in the cancer module 249 (more detail) 22 NA Homo sapiens
TAX013281
GO:0000154 biological process rRNA modification The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecu (more detail) 39 NA Homo sapiens
WIG001584
NF KappaB Activation by EBV NF-KappaB Activation by EBV (more detail) 39 NA Homo sapiens
WAG001156
mRNA Capping (more detail) 27 NA Homo sapiens
TAX016286
GO:0006370 biological process 7 methylguanosine mRNA capping Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript. (more detail) 32 NA Homo sapiens
TAX015544
GO:0005003 molecular function ephrin receptor activity Combining with an ephrin to initiate a change in cell activity. (more detail) 19 NA Homo sapiens
MEX001890
Genes associated with Kinase Inhibitor Kinome 1221 Genes associated with Kinase Inhibitor Kinome_1221, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens
MEX002301
Genes associated with Kinase Inhibitor TCMDC 138201 Genes associated with Kinase Inhibitor TCMDC-138201, curated by the Drug Signature Database (DSigDB) (more detail) 19 25990557 Homo sapiens
MEX001303
Genes associated with Kinase Inhibitor Kinome 1198 Genes associated with Kinase Inhibitor Kinome_1198, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens
MEX001386
Genes associated with Kinase Inhibitor Masitinib Genes associated with Kinase Inhibitor Masitinib, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens
MEX001650
Genes associated with Kinase Inhibitor GNE 7915 Genes associated with Kinase Inhibitor GNE-7915, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens
MEX002011
Genes associated with Kinase Inhibitor SB 203580 Genes associated with Kinase Inhibitor SB 203580, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens
MEX001463
Genes associated with Kinase Inhibitor LDN193189 Genes associated with Kinase Inhibitor LDN193189, curated by the Drug Signature Database (DSigDB). (more detail) 19 25990557 Homo sapiens
MEX002268
Genes associated with Kinase Inhibitor indirubin deriv. 7a Genes associated with Kinase Inhibitor indirubin deriv. 7a, curated by the Drug Signature Database ( (more detail) 19 25990557 Homo sapiens
TAX015295
GO:0004653 molecular function polypeptide N acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosami (more detail) 19 NA Homo sapiens
TAX019211
GO:0016780 molecular function phosphotransferase activity, for other substituted phosphate groups Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl re (more detail) 19 NA Homo sapiens
TAX001275
Genes annotated by the GO term GO:0008080. Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. (more detail) 21 NA Homo sapiens
FOX000697
Genes in the cancer module 4 (more detail) 21 NA Homo sapiens
WAG000383
Chondroitin sulfate biosynthesis Glycosaminoglycans (GAGs) are linear polysaccharide chains consisting of repeating disaccharide unit (more detail) 21 NA Homo sapiens
WAG000805
Selenoamino acid metabolism (more detail) 30 NA Homo sapiens
WIG001202
Genes involved in Signaling by FGFR1 mutants (more detail) 28 NA Homo sapiens
WIG001191
Genes involved in SHC mediated cascade (more detail) 28 NA Homo sapiens
WIG001781
4 1BB Pathway 4-1BB Pathway (more detail) 31 NA Homo sapiens
MEX002032
Genes associated with Kinase Inhibitor Syk Inhibitor II Genes associated with Kinase Inhibitor Syk Inhibitor II, curated by the Drug Signature Database (DSi (more detail) 18 25990557 Homo sapiens
MEX001452
Genes associated with Kinase Inhibitor AGN PC 09LLI8 Genes associated with Kinase Inhibitor AGN-PC-09LLI8, curated by the Drug Signature Database (DSigDB (more detail) 18 25990557 Homo sapiens
MEX001921
Genes associated with Kinase Inhibitor LRRK2 IN 1 Genes associated with Kinase Inhibitor LRRK2-IN-1, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
MEX002326
Genes associated with Kinase Inhibitor Kinome 858 Genes associated with Kinase Inhibitor Kinome_858, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
MEX002295
Genes associated with Kinase Inhibitor NVP TAE684 Genes associated with Kinase Inhibitor NVP-TAE684, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
MEX002201
Genes associated with Kinase Inhibitor 405554 55 4 Genes associated with Kinase Inhibitor 405554-55-4, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
MEX002303
Genes associated with Kinase Inhibitor Kinome 1901 Genes associated with Kinase Inhibitor Kinome_1901, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
MEX002371
Genes associated with Kinase Inhibitor Kinome 454 Genes associated with Kinase Inhibitor Kinome_454, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
MEX002234
Genes associated with Kinase Inhibitor czc 25146 Genes associated with Kinase Inhibitor czc-25146, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
MEX002297
Genes associated with Kinase Inhibitor ( ) Epigallocatechin gallate Genes associated with Kinase Inhibitor (-)-Epigallocatechin gallate, curated by the Drug Signature D (more detail) 18 25990557 Homo sapiens
TAX015215
GO:0004550 molecular function nucleoside diphosphate kinase activity Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. (more detail) 18 NA Homo sapiens
MEX001999
Genes associated with Kinase Inhibitor Quizartinib Genes associated with Kinase Inhibitor Quizartinib, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
TAX001144
Genes annotated by the GO term GO:0034061. Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and primer. (more detail) 18 NA Homo sapiens
MEX001286
Genes associated with Kinase Inhibitor Syk Inhibitor Genes associated with Kinase Inhibitor Syk Inhibitor, curated by the Drug Signature Database (DSigDB (more detail) 18 25990557 Homo sapiens
WIG000998
Genes involved in mRNA Capping (more detail) 29 NA Homo sapiens
MOX013523
Genes associated with Computational Drug Signature LY 294002 Genes associated with Computational Drug Signature LY 294002, curated by the Drug Signature Database (more detail) 29 25990557 Homo sapiens
TAX032235
GO:1901687 biological process glutathione derivative biosynthetic process The chemical reactions and pathways resulting in the formation of glutathione derivative. (more detail) 22 NA Homo sapiens
TAX032234
GO:1901685 biological process glutathione derivative metabolic process The chemical reactions and pathways involving glutathione derivative. (more detail) 22 NA Homo sapiens
WAG000615
Heparan sulfate biosynthesis Heparan sulfate (HS) and heparin (Hep) are glycosaminoglycans with repeating disaccharide units that (more detail) 20 NA Homo sapiens
WAG000406
Nucleotide sugars metabolism (more detail) 30 NA Homo sapiens
TAX020843
GO:0031146 biological process SCF dependent proteasomal ubiquitin dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 23 NA Homo sapiens
TAX024026
GO:0042800 molecular function histone methyltransferase activity (H3 K4 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L (more detail) 17 NA Homo sapiens
TAX027262
GO:0051923 biological process sulfation The addition of a sulfate group to a molecule. (more detail) 17 NA Homo sapiens
TAX018968
GO:0016307 molecular function phosphatidylinositol phosphate kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bis (more detail) 17 NA Homo sapiens
TAX022751
GO:0035173 molecular function histone kinase activity Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-so (more detail) 17 NA Homo sapiens
MEX001560
Genes associated with Kinase Inhibitor TWS119 Genes associated with Kinase Inhibitor TWS119, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
MEX001699
Genes associated with Kinase Inhibitor GW806742X Genes associated with Kinase Inhibitor GW806742X, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
MEX001914
Genes associated with Kinase Inhibitor 929095 18 1 Genes associated with Kinase Inhibitor 929095-18-1, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
MEX001909
Genes associated with Kinase Inhibitor gw8510 Genes associated with Kinase Inhibitor gw8510, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
MEX001654
Genes associated with Kinase Inhibitor CHEMBL2062936 Genes associated with Kinase Inhibitor CHEMBL2062936, curated by the Drug Signature Database (DSigDB (more detail) 17 25990557 Homo sapiens
TAX019197
GO:0016755 molecular function transferase activity, transferring amino acyl groups Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). (more detail) 17 NA Homo sapiens
FOX000659
Genes in the cancer module 349 (more detail) 17 NA Homo sapiens
TAX017218
GO:0008353 molecular function RNA polymerase II CTD heptapeptide repeat kinase activity Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA (more detail) 17 NA Homo sapiens
MEX001683
Genes associated with Kinase Inhibitor Kinome 452 Genes associated with Kinase Inhibitor Kinome_452, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
MEX002318
Genes associated with Kinase Inhibitor GW801372X Genes associated with Kinase Inhibitor GW801372X, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
TAX014870
GO:0003951 molecular function NAD+ kinase activity Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+). (more detail) 17 NA Homo sapiens
MEX002171
Genes associated with Kinase Inhibitor PF 03814735 Genes associated with Kinase Inhibitor PF-03814735, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
MEX001852
Genes associated with Kinase Inhibitor PD166285 Genes associated with Kinase Inhibitor PD166285, curated by the Drug Signature Database (DSigDB). (more detail) 17 25990557 Homo sapiens
TAX015858
GO:0005666 cellular component RNA polymerase III complex RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a (more detail) 17 NA Homo sapiens
TAX025470
GO:0046134 biological process pyrimidine nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of one of a family of organic molecul (more detail) 28 NA Homo sapiens
WAG000071
Formation of transcription coupled NER (TC NER) repair complex (more detail) 28 NA Homo sapiens
WIG000728
Genes involved in Biosynthesis of the N glycan precursor (dolichol lipid linked oligosaccharide, LLO) and transfer to a nascent protein (more detail) 28 NA Homo sapiens
WAG000080
Dual incision reaction in TC NER (more detail) 28 NA Homo sapiens
WAG000321
Transcription coupled NER (TC NER) (more detail) 28 NA Homo sapiens
MOX007549
Genes associated with Computational Drug Signature Cdk9 Inhibitor II Genes associated with Computational Drug Signature Cdk9 Inhibitor II, curated by the Drug Signature (more detail) 21 25990557 Homo sapiens
MOX015246
Genes associated with Computational Drug Signature Sunitinib Genes associated with Computational Drug Signature Sunitinib, curated by the Drug Signature Database (more detail) 19 25990557 Homo sapiens
TAX023514
GO:0038128 biological process ERBB2 signaling pathway A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of rec (more detail) 31 NA Homo sapiens
WIG000133
Regulation of p38 alpha and p38 beta (more detail) 31 NA Homo sapiens
WIG001719
UVB Induced MAPK Signaling UVB-Induced MAPK Signaling (more detail) 29 NA Homo sapiens
WIG000848
Genes involved in Formation of transcription coupled NER (TC NER) repair complex (more detail) 29 NA Homo sapiens
TAX017609
GO:0009218 biological process pyrimidine ribonucleotide metabolic process The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of (more detail) 24 NA Homo sapiens
TAX020343
GO:0030166 biological process proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in (more detail) 32 NA Homo sapiens
FOX000598
Genes in the cancer module 278 (more detail) 32 NA Homo sapiens
TAX017611
GO:0009220 biological process pyrimidine ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a com (more detail) 22 NA Homo sapiens
MOX007314
Genes associated with Computational Drug Signature bisindolylmaleimide i Genes associated with Computational Drug Signature bisindolylmaleimide i, curated by the Drug Signat (more detail) 27 25990557 Homo sapiens
TAX025622
GO:0046527 molecular function glucosyltransferase activity Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrat (more detail) 16 NA Homo sapiens
TAX026206
GO:0048531 molecular function beta 1,3 galactosyltransferase activity Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, formin (more detail) 16 NA Homo sapiens
MEX001830
Genes associated with Kinase Inhibitor CHEMBL463931 Genes associated with Kinase Inhibitor CHEMBL463931, curated by the Drug Signature Database (DSigDB) (more detail) 16 25990557 Homo sapiens
TAX017936
GO:0010485 molecular function H4 histone acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4. (more detail) 16 NA Homo sapiens
FEX000581
Breast Finetti08 16genes Table 1. List of the 16 kinases from the gene cluster identified byquality threshold-clustering (more detail) 16 18245477 Homo sapiens
FEX001680
Leukemia Messina10 16genes Table 4. PK Genes Specifically Expressed in B-NEG Patients Versus at Least 2 Other Groups (more detail) 16 20564080 Homo sapiens
MEX002341
Genes associated with Kinase Inhibitor GW806290X Genes associated with Kinase Inhibitor GW806290X, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
TAX015301
GO:0004659 molecular function prenyltransferase activity Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor). (more detail) 16 NA Homo sapiens
MAX000762
Genes in the green cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. Breast cancer is a heterogeneous disease made of various molecular subtypes with different prognosis (more detail) 16 NA Homo sapiens
TAX015313
GO:0004675 molecular function transmembrane receptor protein serine/threonine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to in (more detail) 16 NA Homo sapiens
TAX015326
GO:0004697 molecular function protein kinase C activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylgl (more detail) 16 NA Homo sapiens
MEX001349
Genes associated with Kinase Inhibitor CHEMBL1982466 Genes associated with Kinase Inhibitor CHEMBL1982466, curated by the Drug Signature Database (DSigDB (more detail) 16 25990557 Homo sapiens
MEX001468
Genes associated with Kinase Inhibitor Kinome 1242 Genes associated with Kinase Inhibitor Kinome_1242, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
MEX001440
Genes associated with Kinase Inhibitor Kinome 866 Genes associated with Kinase Inhibitor Kinome_866, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
WIG000656
Genes involved in Activated point mutants of FGFR2 (more detail) 16 NA Homo sapiens
MAX000763
Genes in the red cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. Breast cancer is a heterogeneous disease made of various molecular subtypes with different prognosis (more detail) 16 NA Homo sapiens
MEX001310
Genes associated with Kinase Inhibitor Kinome 473 Genes associated with Kinase Inhibitor Kinome_473, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
MEX001336
Genes associated with Kinase Inhibitor Kinome 2010 Genes associated with Kinase Inhibitor Kinome_2010, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
MEX001867
Genes associated with Kinase Inhibitor HG 9 91 01 Genes associated with Kinase Inhibitor HG-9-91-01, curated by the Drug Signature Database (DSigDB). (more detail) 16 25990557 Homo sapiens
TAX014881
GO:0003964 molecular function RNA directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes (more detail) 16 NA Homo sapiens
WIG001734
Mechanism of Anthrax Toxins Mechanism of Anthrax Toxins (more detail) 20 NA Homo sapiens
FAX003057
GSEA KEGG Lung Cancer Tissue Explants (Extracellular Vesicles) Purine Metabolism Top 3 KEGG pathways enriched in lung cancer tissue extract extracellular vesicle particles compared (more detail) 30 32795414 Homo sapiens
TAX000237
Genes annotated by the GO term GO:0046474. The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O acyl, O alkyl, or O alkenyl group attached to the glycerol residue. (more detail) 30 NA Homo sapiens
TAX027429
GO:0052695 biological process cellular glucuronidation The modification of an organic chemical by the conjugation of glucuronic acid. The substances result (more detail) 18 NA Homo sapiens
TAX001206
Genes annotated by the GO term GO:0004428. Catalysis of the phosphorylation of myo inositol (1,2,3,5/4,6 cyclohexanehexol) or a phosphatidylinositol. (more detail) 18 NA Homo sapiens
MEX001105
Genes associated with Approved Drug regorafenib Genes associated with Approved Drug regorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
WIG001042
Genes involved in N glycan antennae elongation in the medial/trans Golgi (more detail) 18 NA Homo sapiens
TAX019525
GO:0018345 biological process protein palmitoylation The covalent attachment of a palmitoyl group to a protein. (more detail) 28 NA Homo sapiens
IEI003821
Protein protein interactors of human gene DTX3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DTX3 (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens
WIG002028
Glucuronidation Glucuronidation (more detail) 26 NA Homo sapiens
TAX015592
GO:0005104 molecular function fibroblast growth factor receptor binding Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR). (more detail) 26 NA Homo sapiens
TAX025468
GO:0046132 biological process pyrimidine ribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside i (more detail) 21 NA Homo sapiens
MOX007316
Genes associated with Computational Drug Signature bisindolylmaleimide IX Genes associated with Computational Drug Signature bisindolylmaleimide IX, curated by the Drug Signa (more detail) 21 25990557 Homo sapiens
MOX005959
Genes associated with Computational Drug Signature 4,5,6,7 tetrabromobenzotriazole Genes associated with Computational Drug Signature 4,5,6,7-tetrabromobenzotriazole, curated by the D (more detail) 29 25990557 Homo sapiens
WIG000846
Genes involved in Formation of the HIV 1 Early Elongation Complex (more detail) 29 NA Homo sapiens
TAX019471
GO:0018146 biological process keratan sulfate biosynthetic process The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglyc (more detail) 29 NA Homo sapiens
TAX022522
GO:0034483 molecular function heparan sulfate sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5' (more detail) 15 NA Homo sapiens
MEX001864
Genes associated with Kinase Inhibitor Torin 2 Genes associated with Kinase Inhibitor Torin 2, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
MEX002159
Genes associated with Kinase Inhibitor Kinome 6 Genes associated with Kinase Inhibitor Kinome_6, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
MEX002345
Genes associated with Kinase Inhibitor bisindolylmaleimide i Genes associated with Kinase Inhibitor bisindolylmaleimide i, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens
MEX002164
Genes associated with Kinase Inhibitor GSK1220512A Genes associated with Kinase Inhibitor GSK1220512A, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
MEX001495
Genes associated with Kinase Inhibitor H 89 DIHYDROCHLORIDE Genes associated with Kinase Inhibitor H-89 DIHYDROCHLORIDE, curated by the Drug Signature Database (more detail) 15 25990557 Homo sapiens
FEX001389
Leukemia Chiaretti05 16genes Table 4. Kinase genes with high-level gene expression in samples without known molecular rearrangeme (more detail) 15 16243790 Homo sapiens
MEX001966
Genes associated with Kinase Inhibitor CHEMBL1950303 Genes associated with Kinase Inhibitor CHEMBL1950303, curated by the Drug Signature Database (DSigDB (more detail) 15 25990557 Homo sapiens
MEX001518
Genes associated with Kinase Inhibitor GDC 0941 Genes associated with Kinase Inhibitor GDC-0941, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
TAX013599
GO:0001056 molecular function RNA polymerase III activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA (more detail) 15 NA Homo sapiens
TAX001101
Genes annotated by the GO term GO:0019200. Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule. (more detail) 15 NA Homo sapiens
MAX000761
Genes in the gray cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. Breast cancer is a heterogeneous disease made of various molecular subtypes with different prognosis (more detail) 15 NA Homo sapiens
MEX001079
Genes associated with Approved Drug vargatef Genes associated with Approved Drug vargatef, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
MEX001388
Genes associated with Kinase Inhibitor Kinome 406 Genes associated with Kinase Inhibitor Kinome_406, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
MOX014298
Genes associated with Computational Drug Signature oxindole i Genes associated with Computational Drug Signature oxindole i, curated by the Drug Signature Databas (more detail) 15 25990557 Homo sapiens
TAX001169
Genes annotated by the GO term GO:0004364. Catalysis of the reaction: R X + glutathione = H X + R S glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. (more detail) 15 NA Homo sapiens
MEX001973
Genes associated with Kinase Inhibitor GSK429286A Genes associated with Kinase Inhibitor GSK429286A, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
MEX002180
Genes associated with Kinase Inhibitor Alsterpaullone, 2 Cyanoethyl Genes associated with Kinase Inhibitor Alsterpaullone, 2-Cyanoethyl, curated by the Drug Signature D (more detail) 15 25990557 Homo sapiens
TAX016356
GO:0006474 biological process N terminal protein amino acid acetylation The acetylation of the N-terminal amino acid of proteins. (more detail) 15 NA Homo sapiens
TAX015334
GO:0004708 molecular function MAP kinase kinase activity Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu (more detail) 15 NA Homo sapiens
TAX001063
Genes annotated by the GO term GO:0008375. Catalysis of the transfer of an N acetylglucosaminyl residue from UDP N acetyl glucosamine to an oligosaccharide. (more detail) 15 NA Homo sapiens
MEX002132
Genes associated with Kinase Inhibitor CGP 60474 Genes associated with Kinase Inhibitor CGP 60474, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
MEX001548
Genes associated with Kinase Inhibitor su6656 Genes associated with Kinase Inhibitor su6656, curated by the Drug Signature Database (DSigDB). (more detail) 15 25990557 Homo sapiens
TAX023239
GO:0036065 biological process fucosylation The covalent attachment of a fucosyl group to an acceptor molecule. (more detail) 19 NA Homo sapiens
WIG001165
Genes involved in RNA Polymerase III Chain Elongation (more detail) 17 NA Homo sapiens
MOX011953
Genes associated with Computational Drug Signature CI 1040 Genes associated with Computational Drug Signature CI-1040, curated by the Drug Signature Database ( (more detail) 24 25990557 Homo sapiens
MOX003346
Genes associated with Computational Drug Signature Tozasertib Genes associated with Computational Drug Signature Tozasertib, curated by the Drug Signature Databas (more detail) 24 25990557 Homo sapiens
WIG000587
Pentose and glucuronate interconversions (more detail) 27 NA Homo sapiens
MOX015586
Genes associated with Computational Drug Signature Tozasertib Genes associated with Computational Drug Signature Tozasertib, curated by the Drug Signature Databas (more detail) 22 25990557 Homo sapiens
FOX000560
Genes in the cancer module 233 (more detail) 22 NA Homo sapiens
WIG000875
Genes involved in Glucuronidation (more detail) 18 NA Homo sapiens
TAX001315
Genes annotated by the GO term GO:0016776. Catalysis of the transfer of a phosphorus containing group from one compound (donor) to a phosphate group (acceptor). (more detail) 18 NA Homo sapiens
TAX025532
GO:0046341 biological process CDP diacylglycerol metabolic process The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substanc (more detail) 14 NA Homo sapiens
TAX017309
GO:0008499 molecular function UDP galactose:beta N acetylglucosamine beta 1,3 galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosam (more detail) 14 NA Homo sapiens
TAX019632
GO:0019206 molecular function nucleoside kinase activity Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate. (more detail) 14 NA Homo sapiens
TAX026437
GO:0050321 molecular function tau protein kinase activity Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein. (more detail) 14 NA Homo sapiens
TAX025821
GO:0046940 biological process nucleoside monophosphate phosphorylation The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a (more detail) 14 NA Homo sapiens
TAX022795
GO:0035269 biological process protein O linked mannosylation The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl (more detail) 14 NA Homo sapiens
MEX001428
Genes associated with Kinase Inhibitor Imatinib Genes associated with Kinase Inhibitor Imatinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002415
Genes associated with Kinase Inhibitor Ceritinib Genes associated with Kinase Inhibitor Ceritinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
TAX015333
GO:0004707 molecular function MAP kinase activity Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphoryla (more detail) 14 NA Homo sapiens
MEX002228
Genes associated with Kinase Inhibitor Kinome 3196 Genes associated with Kinase Inhibitor Kinome_3196, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002269
Genes associated with Kinase Inhibitor 841290 80 0 Genes associated with Kinase Inhibitor 841290-80-0, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002283
Genes associated with Kinase Inhibitor Kinome 708 Genes associated with Kinase Inhibitor Kinome_708, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002015
Genes associated with Kinase Inhibitor BS 181 Genes associated with Kinase Inhibitor BS-181, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002411
Genes associated with Kinase Inhibitor Imatinib Genes associated with Kinase Inhibitor Imatinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002083
Genes associated with Kinase Inhibitor Go 6976 Genes associated with Kinase Inhibitor Go 6976, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX001945
Genes associated with Kinase Inhibitor Kinome 239 Genes associated with Kinase Inhibitor Kinome_239, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX001718
Genes associated with Kinase Inhibitor Kinome 450 Genes associated with Kinase Inhibitor Kinome_450, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002419
Genes associated with Kinase Inhibitor Ibrutinib Genes associated with Kinase Inhibitor Ibrutinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX001207
Genes associated with Kinase Inhibitor Kinome 439 Genes associated with Kinase Inhibitor Kinome_439, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX001318
Genes associated with Kinase Inhibitor Ibrutinib Genes associated with Kinase Inhibitor Ibrutinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002375
Genes associated with Kinase Inhibitor dorsomorphin Genes associated with Kinase Inhibitor dorsomorphin, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens
MEX001709
Genes associated with Kinase Inhibitor Kinome 1216 Genes associated with Kinase Inhibitor Kinome_1216, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002082
Genes associated with Kinase Inhibitor GW795493X Genes associated with Kinase Inhibitor GW795493X, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
WIG000838
Genes involved in FGFR1 ligand binding and activation (more detail) 14 NA Homo sapiens
PEX001911
Sulfotransfer 1: Sulfotransferase domain (more detail) 14 NA Homo sapiens
TAX001142
Genes annotated by the GO term GO:0003887. Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer. (more detail) 14 NA Homo sapiens
WIG001041
Genes involved in N Glycan antennae elongation (more detail) 14 NA Homo sapiens
MEX001964
Genes associated with Kinase Inhibitor Kinome 859 Genes associated with Kinase Inhibitor Kinome_859, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002361
Genes associated with Kinase Inhibitor CHEMBL495696 Genes associated with Kinase Inhibitor CHEMBL495696, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens
MEX002123
Genes associated with Kinase Inhibitor Fostamatinib Genes associated with Kinase Inhibitor Fostamatinib, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens
MEX001731
Genes associated with Kinase Inhibitor TCMDC 141371 Genes associated with Kinase Inhibitor TCMDC-141371, curated by the Drug Signature Database (DSigDB) (more detail) 14 25990557 Homo sapiens
MEX002412
Genes associated with Kinase Inhibitor Tofacitinib Genes associated with Kinase Inhibitor Tofacitinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
WAG000405
Keratan sulfate biosynthesis Keratan sulfate (KS) is a glycosaminoglycan with the basic disaccharide unit of N-acetyllactosamine, (more detail) 14 NA Homo sapiens
WIG000530
Glycosaminoglycan biosynthesis keratan sulfate (more detail) 14 NA Homo sapiens
MEX002204
Genes associated with Kinase Inhibitor curcumin Genes associated with Kinase Inhibitor curcumin, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002094
Genes associated with Kinase Inhibitor Tasocitinib Genes associated with Kinase Inhibitor Tasocitinib, curated by the Drug Signature Database (DSigDB). (more detail) 14 25990557 Homo sapiens
MEX002135
Genes associated with Kinase Inhibitor Bisindolylmaleimide XI, HCl Genes associated with Kinase Inhibitor Bisindolylmaleimide XI, HCl, curated by the Drug Signature Da (more detail) 14 25990557 Homo sapiens
TAX019763
GO:0019585 biological process glucuronate metabolic process The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the (more detail) 23 NA Homo sapiens
TAX016106
GO:0006063 biological process uronic acid metabolic process The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived (more detail) 23 NA Homo sapiens
TAX001186
Genes annotated by the GO term GO:0004402. Catalysis of the reaction: acetyl CoA + histone = CoA + acetyl histone. (more detail) 16 NA Homo sapiens
TAX001165
Genes annotated by the GO term GO:0008378. Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid. (more detail) 16 NA Homo sapiens
TAX001361
Genes annotated by the GO term GO:0034062. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template. (more detail) 16 NA Homo sapiens
TAX020950
GO:0031365 biological process N terminal protein amino acid modification The alteration of the N-terminal amino acid residue in a protein. (more detail) 26 NA Homo sapiens
WIG000136
p38 MAPK signaling pathway (more detail) 26 NA Homo sapiens
IEI005481
Protein protein interactors of human gene GRB14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GRB14 (SwissProt ID= (more detail) 21 17535438 Homo sapiens
WIG000736
Genes involved in CD28 dependent PI3K/Akt signaling (more detail) 21 NA Homo sapiens
WIG000616
Selenoamino acid metabolism (more detail) 24 NA Homo sapiens
TAX000537
Genes annotated by the GO term GO:0006497. The covalent or non covalent attachment of lipid moieties to an amino acid in a protein. (more detail) 24 NA Homo sapiens
TAX017546
GO:0009148 biological process pyrimidine nucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate (more detail) 19 NA Homo sapiens
WIG001169
Genes involved in RNA Polymerase III Transcription Termination (more detail) 19 NA Homo sapiens
TAX024200
GO:0043174 biological process nucleoside salvage Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucl (more detail) 17 NA Homo sapiens
IEI011407
Protein protein interactors of human gene RNF166 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF166 (SwissProt ID (more detail) 17 17535438 Homo sapiens
WIG002024
Sulfation Biotransformation Reaction Sulfation Biotransformation Reaction (more detail) 17 NA Homo sapiens
TAX017545
GO:0009147 biological process pyrimidine nucleoside triphosphate metabolic process The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consist (more detail) 22 NA Homo sapiens
WIG000888
Genes involved in GRB2 events in ERBB2 signaling (more detail) 22 NA Homo sapiens
FEX000744
Breast Speers09 24genes Supplementary Table 3. Kinases overexpressed in ER-positive breast cancer (more detail) 22 19808870 Homo sapiens
MEX001472
Genes associated with Kinase Inhibitor PI 103 Genes associated with Kinase Inhibitor PI-103, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
PEX001420
Pkinase C: Protein kinase C terminal domain (more detail) 13 NA Homo sapiens
MOX006679
Genes associated with Computational Drug Signature AGN PC 00BUNE Genes associated with Computational Drug Signature AGN-PC-00BUNE, curated by the Drug Signature Data (more detail) 13 25990557 Homo sapiens
MEX001488
Genes associated with Kinase Inhibitor GSK2213727A Genes associated with Kinase Inhibitor GSK2213727A, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MOX015215
Genes associated with Computational Drug Signature SU11652 Genes associated with Computational Drug Signature SU11652, curated by the Drug Signature Database ( (more detail) 13 25990557 Homo sapiens
MEX002319
Genes associated with Kinase Inhibitor Kinome 491 Genes associated with Kinase Inhibitor Kinome_491, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MEX001397
Genes associated with Kinase Inhibitor AGN PC 04WTVX Genes associated with Kinase Inhibitor AGN-PC-04WTVX, curated by the Drug Signature Database (DSigDB (more detail) 13 25990557 Homo sapiens
MEX002215
Genes associated with Kinase Inhibitor resveratrol Genes associated with Kinase Inhibitor resveratrol, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MEX002003
Genes associated with Kinase Inhibitor Kinome 474 Genes associated with Kinase Inhibitor Kinome_474, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MEX002041
Genes associated with Kinase Inhibitor Kinome 506 Genes associated with Kinase Inhibitor Kinome_506, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MEX001688
Genes associated with Kinase Inhibitor GW575808A Genes associated with Kinase Inhibitor GW575808A, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
TAX001333
Genes annotated by the GO term GO:0008276. Catalysis of the transfer of a methyl group (CH3 ) to a protein. (more detail) 13 NA Homo sapiens
MEX001504
Genes associated with Kinase Inhibitor PKCbeta Inhibitor Genes associated with Kinase Inhibitor PKCbeta Inhibitor, curated by the Drug Signature Database (DS (more detail) 13 25990557 Homo sapiens
MEX002141
Genes associated with Kinase Inhibitor roscovitine Genes associated with Kinase Inhibitor roscovitine, curated by the Drug Signature Database (DSigDB). (more detail) 13 25990557 Homo sapiens
MEX001844
Genes associated with Kinase Inhibitor CHEMBL1999931 Genes associated with Kinase Inhibitor CHEMBL1999931, curated by the Drug Signature Database (DSigDB (more detail) 13 25990557 Homo sapiens
MOX005546
Genes associated with Computational Drug Signature 1H Pyrrole 2,5 dione, 3,4 diphenyl Genes associated with Computational Drug Signature 1H-Pyrrole-2,5-dione, 3,4-diphenyl-, curated by t (more detail) 13 25990557 Homo sapiens
MOX005545
Genes associated with Computational Drug Signature 1H Pyrrole 2,5 dione, 3,4 bis(4 methoxyphenyl) Genes associated with Computational Drug Signature 1H-Pyrrole-2,5-dione, 3,4-bis(4-methoxyphenyl)-, (more detail) 13 25990557 Homo sapiens
TAX018825
GO:0016024 biological process CDP diacylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacyl (more detail) 13 NA Homo sapiens
TAX022498
GO:0034450 molecular function ubiquitin ubiquitin ligase activity Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction (more detail) 13 NA Homo sapiens
TAX019017
GO:0016423 molecular function tRNA (guanine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA contain (more detail) 13 NA Homo sapiens
TAX017253
GO:0008417 molecular function fucosyltransferase activity Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate (more detail) 13 NA Homo sapiens
TAX000571
Genes annotated by the GO term GO:0030166. The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. (more detail) 15 NA Homo sapiens
TAX018938
GO:0016254 biological process preassembly of GPI anchor in ER membrane The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the e (more detail) 15 NA Homo sapiens
IEI014615
Protein protein interactors of human gene UBOX5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBOX5 (SwissProt ID= (more detail) 20 17535438 Homo sapiens
TAX000572
Genes annotated by the GO term GO:0006029. The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. (more detail) 20 NA Homo sapiens
WIG001167
Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter (more detail) 23 NA Homo sapiens
WIG000877
Genes involved in Glutathione conjugation (more detail) 23 NA Homo sapiens
TAX000539
Genes annotated by the GO term GO:0006493. The formation of O glycans by addition of glycosyl groups either to the hydroxyl group of peptidyl serine, peptidyl threonine, peptidyl hydroxylysine, or peptidyl hydroxyproline, or to the phenol group of peptidyl tyrosine. (more detail) 18 NA Homo sapiens
MEX000802
Genes associated with Approved Drug lapatinib Genes associated with Approved Drug lapatinib, curated by the Drug Signature Database (DSigDB). (more detail) 18 25990557 Homo sapiens
WIG001954
Triacylglyceride Synthesis Triacylglyceride Synthesis (more detail) 21 NA Homo sapiens
TAX019500
GO:0018216 biological process peptidyl arginine methylation The addition of a methyl group to an arginine residue in a protein. (more detail) 16 NA Homo sapiens
WAG001358
Synthesis of glycosylphosphatidylinositol (GPI) (more detail) 16 NA Homo sapiens
TAX017600
GO:0009208 biological process pyrimidine ribonucleoside triphosphate metabolic process The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound con (more detail) 16 NA Homo sapiens
TAX018950
GO:0016273 molecular function arginine N methyltransferase activity Enables the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine (more detail) 12 NA Homo sapiens
TAX001277
Genes annotated by the GO term GO:0008170. Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. (more detail) 12 NA Homo sapiens
WIG000840
Genes involved in FGFR4 ligand binding and activation (more detail) 12 NA Homo sapiens
TAX014950
GO:0004062 molecular function aryl sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bispho (more detail) 12 NA Homo sapiens
WIG000839
Genes involved in FGFR2c ligand binding and activation (more detail) 12 NA Homo sapiens
PEX001140
GST N: Glutathione S transferase, N terminal domain Function: conjugation of reduced glutathione to a variety of targets. Also included in the alignment (more detail) 12 NA Homo sapiens
MEX001329
Genes associated with Kinase Inhibitor Afatinib Genes associated with Kinase Inhibitor Afatinib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001913
Genes associated with Kinase Inhibitor Purvalanol B Genes associated with Kinase Inhibitor Purvalanol B, curated by the Drug Signature Database (DSigDB) (more detail) 12 25990557 Homo sapiens
MEX001610
Genes associated with Kinase Inhibitor CHEMBL1965660 Genes associated with Kinase Inhibitor CHEMBL1965660, curated by the Drug Signature Database (DSigDB (more detail) 12 25990557 Homo sapiens
MEX002340
Genes associated with Kinase Inhibitor Kinome 10 Genes associated with Kinase Inhibitor Kinome_10, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX002002
Genes associated with Kinase Inhibitor Aurora Kinase/Cdk Inhibitor Genes associated with Kinase Inhibitor Aurora Kinase/Cdk Inhibitor, curated by the Drug Signature Da (more detail) 12 25990557 Homo sapiens
MEX001775
Genes associated with Kinase Inhibitor Kinome 3513 Genes associated with Kinase Inhibitor Kinome_3513, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001209
Genes associated with Kinase Inhibitor 172889 26 8 Genes associated with Kinase Inhibitor 172889-26-8, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001427
Genes associated with Kinase Inhibitor GSK1326255A Genes associated with Kinase Inhibitor GSK1326255A, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
TAX001240
Genes annotated by the GO term GO:0004707. Catalysis of the phosphorylation of proteins. Mitogen activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation or differentiation inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli. (more detail) 12 NA Homo sapiens
MEX001634
Genes associated with Kinase Inhibitor Tandutinib Genes associated with Kinase Inhibitor Tandutinib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001992
Genes associated with Kinase Inhibitor bisindolylmaleimide i Genes associated with Kinase Inhibitor bisindolylmaleimide i, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens
TAX018951
GO:0016274 molecular function protein arginine N methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine (more detail) 12 NA Homo sapiens
MEX001423
Genes associated with Kinase Inhibitor Kinome 249 Genes associated with Kinase Inhibitor Kinome_249, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001931
Genes associated with Kinase Inhibitor GW305178X Genes associated with Kinase Inhibitor GW305178X, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001944
Genes associated with Kinase Inhibitor GSK1173862A Genes associated with Kinase Inhibitor GSK1173862A, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
PEX001280
Methyltransf 25: Methyltransferase domain This family appears to be a methyltransferase domain. (more detail) 12 NA Homo sapiens
TAX001062
Genes annotated by the GO term GO:0008376. Catalysis of the transfer of an N acetylgalactosaminyl residue from UDP N acetyl galactosamine to an oligosaccharide. (more detail) 12 NA Homo sapiens
TAX001232
Genes annotated by the GO term GO:0001727. Catalysis of the phosphorylation of a simple or complex lipid. (more detail) 12 NA Homo sapiens
MEX001323
Genes associated with Kinase Inhibitor Tyrphostin AG 1478 Genes associated with Kinase Inhibitor Tyrphostin AG 1478, curated by the Drug Signature Database (D (more detail) 12 25990557 Homo sapiens
MEX001933
Genes associated with Kinase Inhibitor rottlerin Genes associated with Kinase Inhibitor rottlerin, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX002367
Genes associated with Kinase Inhibitor Kinome 501 Genes associated with Kinase Inhibitor Kinome_501, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX002408
Genes associated with Kinase Inhibitor Afatinib Genes associated with Kinase Inhibitor Afatinib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001816
Genes associated with Kinase Inhibitor Kinome 490 Genes associated with Kinase Inhibitor Kinome_490, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001806
Genes associated with Kinase Inhibitor Vandetanib Genes associated with Kinase Inhibitor Vandetanib, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX001510
Genes associated with Kinase Inhibitor go 6983 Genes associated with Kinase Inhibitor go 6983, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
PEX001984
Methyltransf 11: Methyltransferase domain Members of this family are SAM dependent methyltransferases. (more detail) 12 NA Homo sapiens
MEX001644
Genes associated with Kinase Inhibitor 172889 27 9 Genes associated with Kinase Inhibitor 172889-27-9, curated by the Drug Signature Database (DSigDB). (more detail) 12 25990557 Homo sapiens
MEX002294
Genes associated with Kinase Inhibitor PYRAZOLOPYRIDAZINE 1 Genes associated with Kinase Inhibitor PYRAZOLOPYRIDAZINE 1, curated by the Drug Signature Database (more detail) 12 25990557 Homo sapiens
FEX001162
Immune Kong10 12genes ImmPort TGF betaFamilyMemberReceptors ImmPort genelist of cytokine receptors: TGF-beta Family Member Receptors (more detail) 12 20460173 Homo sapiens
TAX019207
GO:0016775 molecular function phosphotransferase activity, nitrogenous group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenou (more detail) 12 NA Homo sapiens
TAX019214
GO:0016783 molecular function sulfurtransferase activity Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor). (more detail) 12 NA Homo sapiens
TAX018169
GO:0010857 molecular function calcium dependent protein kinase activity Catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the pres (more detail) 12 NA Homo sapiens
TAX022775
GO:0035246 biological process peptidyl arginine N methylation The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein. (more detail) 12 NA Homo sapiens
TAX020718
GO:0030914 cellular component STAGA complex A large multiprotein complex that possesses histone acetyltransferase and is involved in regulation (more detail) 12 NA Homo sapiens
WIG000783
Genes involved in Cytosolic sulfonation of small molecules (more detail) 14 NA Homo sapiens
MOX007338
Genes associated with Computational Drug Signature BMS 536924 Genes associated with Computational Drug Signature BMS-536924, curated by the Drug Signature Databas (more detail) 14 25990557 Homo sapiens
WAG000724
RNA Polymerase I Transcription (more detail) 19 NA Homo sapiens
WAG001130
RNA Polymerase I Chain Elongation (more detail) 19 NA Homo sapiens
IEI012263
Protein protein interactors of human gene SLA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SLA (SwissProt ID=Q1 (more detail) 19 17535438 Homo sapiens
WIG001248
Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) (more detail) 17 NA Homo sapiens
WAG000661
p38 MAPK signaling pathway (more detail) 17 NA Homo sapiens
MOX003478
Genes associated with Computational Drug Signature NVP TAE684 Genes associated with Computational Drug Signature NVP-TAE684, curated by the Drug Signature Databas (more detail) 17 25990557 Homo sapiens
WAG000314
RNA Polymerase I Transcription Initiation (more detail) 20 NA Homo sapiens
WAG000705
RNA Polymerase I Transcription Termination (more detail) 20 NA Homo sapiens
WAG001545
RNA Polymerase I Promoter Escape (more detail) 20 NA Homo sapiens
WIG001177
Genes involved in RNA Polymerase I Transcription Termination (more detail) 20 NA Homo sapiens
WAG000115
RNA Polymerase I Promoter Clearance (more detail) 20 NA Homo sapiens
IEI003380
Protein protein interactors of human gene DCUN1D5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCUN1D5 (SwissProt I (more detail) 15 17535438 Homo sapiens
WIG000532
Glycosphingolipid biosynthesis ganglio series (more detail) 15 NA Homo sapiens
TAX017601
GO:0009209 biological process pyrimidine ribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosp (more detail) 15 NA Homo sapiens
TAX016369
GO:0006490 biological process oligosaccharide lipid intermediate biosynthetic process The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermedi (more detail) 15 NA Homo sapiens
TAX017810
GO:0009931 molecular function calcium dependent protein serine/threonine kinase activity Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a pro (more detail) 11 NA Homo sapiens
TAX027431
GO:0052697 biological process xenobiotic glucuronidation The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant gluc (more detail) 11 NA Homo sapiens
TAX024446
GO:0043560 molecular function insulin receptor substrate binding Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins (more detail) 11 NA Homo sapiens
TAX025414
GO:0046051 biological process UTP metabolic process The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate. (more detail) 11 NA Homo sapiens
MOX009947
Genes associated with Computational Drug Signature CHEMBL380598 Genes associated with Computational Drug Signature CHEMBL380598, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens
TAX015008
GO:0004143 molecular function diacylglycerol kinase activity Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate. (more detail) 11 NA Homo sapiens
WIG001194
Genes involved in Signaling by activated point mutants of FGFR1 (more detail) 11 NA Homo sapiens
WIG001203
Genes involved in Signaling by FGFR3 mutants (more detail) 11 NA Homo sapiens
TAX015108
GO:0004385 molecular function guanylate kinase activity Catalysis of the reaction: ATP + GMP = ADP + GDP. (more detail) 11 NA Homo sapiens
TAX015294
GO:0004652 molecular function polynucleotide adenylyltransferase activity Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition o (more detail) 11 NA Homo sapiens
MEX001348
Genes associated with Kinase Inhibitor GW589933X Genes associated with Kinase Inhibitor GW589933X, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX001639
Genes associated with Kinase Inhibitor Ruboxistaurin Genes associated with Kinase Inhibitor Ruboxistaurin, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens
MEX001817
Genes associated with Kinase Inhibitor alsterpaullone Genes associated with Kinase Inhibitor alsterpaullone, curated by the Drug Signature Database (DSigD (more detail) 11 25990557 Homo sapiens
TAX013598
GO:0001055 molecular function RNA polymerase II activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA (more detail) 11 NA Homo sapiens
WIG000737
Genes involved in CD28 dependent Vav1 pathway (more detail) 11 NA Homo sapiens
MEX001927
Genes associated with Kinase Inhibitor Kinome 528 Genes associated with Kinase Inhibitor Kinome_528, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX002305
Genes associated with Kinase Inhibitor Kinome 248 Genes associated with Kinase Inhibitor Kinome_248, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX001674
Genes associated with Kinase Inhibitor InSolution¿¿KT5720 Genes associated with Kinase Inhibitor InSolution¿¿KT5720, curated by the Drug Signa (more detail) 11 25990557 Homo sapiens
MEX001820
Genes associated with Kinase Inhibitor CHEMBL1970317 Genes associated with Kinase Inhibitor CHEMBL1970317, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens
MEX001687
Genes associated with Kinase Inhibitor Saracatinib Genes associated with Kinase Inhibitor Saracatinib, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX001625
Genes associated with Kinase Inhibitor PDK1/Akt/Flt Dual Pathway Inhibitor Genes associated with Kinase Inhibitor PDK1/Akt/Flt Dual Pathway Inhibitor, curated by the Drug Sign (more detail) 11 25990557 Homo sapiens
MEX002233
Genes associated with Kinase Inhibitor CHEMBL1969102 Genes associated with Kinase Inhibitor CHEMBL1969102, curated by the Drug Signature Database (DSigDB (more detail) 11 25990557 Homo sapiens
MEX002211
Genes associated with Kinase Inhibitor Kinome 812 Genes associated with Kinase Inhibitor Kinome_812, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
TAX017216
GO:0008349 molecular function MAP kinase kinase kinase kinase activity Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kin (more detail) 11 NA Homo sapiens
MOX012940
Genes associated with Computational Drug Signature GSK690693 Genes associated with Computational Drug Signature GSK690693, curated by the Drug Signature Database (more detail) 11 25990557 Homo sapiens
MEX001836
Genes associated with Kinase Inhibitor CHEMBL456252 Genes associated with Kinase Inhibitor CHEMBL456252, curated by the Drug Signature Database (DSigDB) (more detail) 11 25990557 Homo sapiens
TAX015253
GO:0004596 molecular function peptide alpha N acetyltransferase activity Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the (more detail) 11 NA Homo sapiens
MEX001244
Genes associated with Kinase Inhibitor 761437 28 9 Genes associated with Kinase Inhibitor 761437-28-9, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
TAX015893
GO:0005736 cellular component RNA polymerase I complex RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a mu (more detail) 11 NA Homo sapiens
PEX002663
PARP: Poly(ADP ribose) polymerase catalytic domain Poly(ADP-ribose) polymerase catalyses the covalent attachment of ADP-ribose units from NAD+ to itsel (more detail) 11 NA Homo sapiens
TAX000560
Genes annotated by the GO term GO:0000209. Addition of multiple ubiquitin moieties to a protein, forming a ubiquitin chain. (more detail) 11 NA Homo sapiens
MEX001203
Genes associated with Kinase Inhibitor Cdk2 Inhibitor IV, NU6140 Genes associated with Kinase Inhibitor Cdk2 Inhibitor IV, NU6140, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens
TAX015049
GO:0004312 molecular function fatty acid synthase activity Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n (more detail) 11 NA Homo sapiens
MOX014978
Genes associated with Computational Drug Signature Saracatinib Genes associated with Computational Drug Signature Saracatinib, curated by the Drug Signature Databa (more detail) 11 25990557 Homo sapiens
MEX001255
Genes associated with Kinase Inhibitor Kinome 1199 Genes associated with Kinase Inhibitor Kinome_1199, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
MEX001269
Genes associated with Kinase Inhibitor A 443654 Genes associated with Kinase Inhibitor A-443654, curated by the Drug Signature Database (DSigDB). (more detail) 11 25990557 Homo sapiens
TAX019450
GO:0018027 biological process peptidyl lysine dimethylation The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine. (more detail) 13 NA Homo sapiens
WIG001150
Genes involved in Regulation of signaling by CBL (more detail) 18 NA Homo sapiens
TAX015857
GO:0005665 cellular component RNA polymerase II, core complex RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a m (more detail) 18 NA Homo sapiens
MOX013298
Genes associated with Computational Drug Signature KN 62 Genes associated with Computational Drug Signature KN-62, curated by the Drug Signature Database (DS (more detail) 18 25990557 Homo sapiens
TAX023906
GO:0042575 cellular component DNA polymerase complex A protein complex that possesses DNA polymerase activity and is involved in template directed synthe (more detail) 16 NA Homo sapiens
TAX016068
GO:0006004 biological process fucose metabolic process The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers (more detail) 16 NA Homo sapiens
TAX018435
GO:0015012 biological process heparan sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, (more detail) 16 NA Homo sapiens
MOX003367
Genes associated with Computational Drug Signature Lapatinib Genes associated with Computational Drug Signature Lapatinib, curated by the Drug Signature Database (more detail) 16 25990557 Homo sapiens
WAG000640
role of erk5 in neuronal survival pathway Axons extend significant distances to innervate target tissues. At the site of innervation, target (more detail) 19 NA Homo sapiens
TAX016026
GO:0005942 cellular component phosphatidylinositol 3 kinase complex A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any p (more detail) 19 NA Homo sapiens
WIG000654
Genes involved in Activated AMPK stimulates fatty acid oxidation in muscle (more detail) 19 NA Homo sapiens
TAX025406
GO:0046036 biological process CTP metabolic process The chemical reactions and pathways involving CTP, cytidine triphosphate. (more detail) 14 NA Homo sapiens
PEX001173
zf C3HC4 3: Zinc finger, C3HC4 type (RING finger) (more detail) 14 NA Homo sapiens
TAX016367
GO:0006488 biological process dolichol linked oligosaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, u (more detail) 14 NA Homo sapiens
WIG001315
Genes involved in Viral Messenger RNA Synthesis (more detail) 14 NA Homo sapiens
WIG000533
Glycosphingolipid biosynthesis globo series (more detail) 14 NA Homo sapiens
TAX016205
GO:0006241 biological process CTP biosynthetic process The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate. (more detail) 14 NA Homo sapiens
WAG001326
MicroRNA biogenesis (more detail) 14 NA Homo sapiens
WIG000096
IL5 mediated signaling events (more detail) 14 NA Homo sapiens
MAX002048
Composition of the 2 MDa human STAGA complex containing KAT2A [GeneID=2648] . Transcription in eukaryotes is a tightly regulated, multistep process. Gene-specific transcriptional (more detail) 14 NA Homo sapiens
TAX025721
GO:0046710 biological process GDP metabolic process The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate. (more detail) 12 NA Homo sapiens
WAG001527
RNA Polymerase III Chain Elongation (more detail) 12 NA Homo sapiens
WAG000909
RNA Polymerase III Transcription Termination (more detail) 12 NA Homo sapiens
MOX014858
Genes associated with Computational Drug Signature Ro 4396686 Genes associated with Computational Drug Signature Ro-4396686, curated by the Drug Signature Databas (more detail) 12 25990557 Homo sapiens
WAG000308
RNA Polymerase III Transcription (more detail) 12 NA Homo sapiens
MOX012907
Genes associated with Computational Drug Signature Go 6976 Genes associated with Computational Drug Signature Go 6976, curated by the Drug Signature Database ( (more detail) 12 25990557 Homo sapiens
TAX001239
Genes annotated by the GO term GO:0000030. Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid. (more detail) 10 NA Homo sapiens
MEX001222
Genes associated with Kinase Inhibitor GSK 3 Inhibitor XIII Genes associated with Kinase Inhibitor GSK-3 Inhibitor XIII, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
MEX001588
Genes associated with Kinase Inhibitor AG F 35231 Genes associated with Kinase Inhibitor AG-F-35231, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
TAX001163
Genes annotated by the GO term GO:0008417. Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid. (more detail) 10 NA Homo sapiens
MEX001630
Genes associated with Kinase Inhibitor Kinome 2812 Genes associated with Kinase Inhibitor Kinome_2812, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX001900
Genes associated with Kinase Inhibitor BMS 345541 free base Genes associated with Kinase Inhibitor BMS-345541 free base, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
TAX001188
Genes annotated by the GO term GO:0042054. Catalysis of the transfer of a methyl group (CH3 ) to a histone. (more detail) 10 NA Homo sapiens
PEX001303
Cyclin N: Cyclin, N terminal domain Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a Uracil-DNA glycosylase that is r (more detail) 10 NA Homo sapiens
MEX002390
Genes associated with Kinase Inhibitor CHEMBL212299 Genes associated with Kinase Inhibitor CHEMBL212299, curated by the Drug Signature Database (DSigDB) (more detail) 10 25990557 Homo sapiens
MEX001743
Genes associated with Kinase Inhibitor CHEMBL1956068 Genes associated with Kinase Inhibitor CHEMBL1956068, curated by the Drug Signature Database (DSigDB (more detail) 10 25990557 Homo sapiens
MEX002334
Genes associated with Kinase Inhibitor Nilotinib Genes associated with Kinase Inhibitor Nilotinib, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX001641
Genes associated with Kinase Inhibitor 1 [4 (4 Aminothieno[2,3 D]pyrimidin 5 Yl)phenyl] 3 [2 Fluoro 5 (Trifluoromethyl)phenyl]urea Genes associated with Kinase Inhibitor 1-[4-(4-Aminothieno[2,3-D]pyrimidin-5-Yl)phenyl]-3-[2-Fluoro- (more detail) 10 25990557 Homo sapiens
MEX001313
Genes associated with Kinase Inhibitor GSK2220400A Genes associated with Kinase Inhibitor GSK2220400A, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
TAX016200
GO:0006228 biological process UTP biosynthetic process The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate. (more detail) 10 NA Homo sapiens
MEX002193
Genes associated with Kinase Inhibitor Kinome 1218 Genes associated with Kinase Inhibitor Kinome_1218, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX002168
Genes associated with Kinase Inhibitor GW782612X Genes associated with Kinase Inhibitor GW782612X, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX001737
Genes associated with Kinase Inhibitor GW612286X Genes associated with Kinase Inhibitor GW612286X, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MOX014394
Genes associated with Computational Drug Signature PD166326 Genes associated with Computational Drug Signature PD166326, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
MEX001919
Genes associated with Kinase Inhibitor BMS 345541 free base Genes associated with Kinase Inhibitor BMS-345541 free base, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
MOX014383
Genes associated with Computational Drug Signature PD 0173956 Genes associated with Computational Drug Signature PD-0173956, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens
MEX002245
Genes associated with Kinase Inhibitor Kinome 192 Genes associated with Kinase Inhibitor Kinome_192, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
TAX000534
Genes annotated by the GO term GO:0006471. The transfer, from NAD, of ADP ribose to protein amino acids. (more detail) 10 NA Homo sapiens
MOX008993
Genes associated with Computational Drug Signature CHEMBL230686 Genes associated with Computational Drug Signature CHEMBL230686, curated by the Drug Signature Datab (more detail) 10 25990557 Homo sapiens
MEX002075
Genes associated with Kinase Inhibitor 1 [4 (4 aminothieno[2,3 d]pyrimidin 5 yl)phenyl] 3 (3 methylphenyl)urea Genes associated with Kinase Inhibitor 1-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-(3-methylp (more detail) 10 25990557 Homo sapiens
MEX001700
Genes associated with Kinase Inhibitor PD 173074 Genes associated with Kinase Inhibitor PD 173074, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
MEX001679
Genes associated with Kinase Inhibitor Kinome 504 Genes associated with Kinase Inhibitor Kinome_504, curated by the Drug Signature Database (DSigDB). (more detail) 10 25990557 Homo sapiens
FOX000430
Genes in the cancer module 101 (more detail) 10 NA Homo sapiens
TAX001377
Genes annotated by the GO term GO:0008373. Catalysis of the formation of sialylglycoconjugates via transfer of the sialic acid group from CMP to one of several glycoconjugate acceptors. (more detail) 10 NA Homo sapiens
TAX015237
GO:0004576 molecular function oligosaccharyl transferase activity Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbo (more detail) 10 NA Homo sapiens
TAX019449
GO:0018026 biological process peptidyl lysine monomethylation The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine. (more detail) 10 NA Homo sapiens
TAX028951
GO:0070475 biological process rRNA base methylation The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in (more detail) 10 NA Homo sapiens
TAX022776
GO:0035247 biological process peptidyl arginine omega N methylation The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue (more detail) 10 NA Homo sapiens
IEI015826
Protein protein interactors of human gene ZNRF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNRF1 (SwissProt ID= (more detail) 17 17535438 Homo sapiens
TAX033408
GO:1904355 biological process positive regulation of telomere capping Any process that activates or increases the frequency, rate or extent of telomere capping. (more detail) 17 NA Homo sapiens
TAX025407
GO:0046037 biological process GMP metabolic process The chemical reactions and pathways involving GMP, guanosine monophosphate. (more detail) 17 NA Homo sapiens
IEI010346
Protein protein interactors of human gene PPP1R14A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PPP1R14A (SwissProt (more detail) 17 17535438 Homo sapiens
MOX014380
Genes associated with Computational Drug Signature PD 173074 Genes associated with Computational Drug Signature PD 173074, curated by the Drug Signature Database (more detail) 17 25990557 Homo sapiens
FEX001589
Leukemia Sanchez Guijo08 19genes SuppTable2o Genes involved in protein phosphorilation (more detail) 17 18722011 Homo sapiens
WIG000059
ErbB receptor signaling network (more detail) 15 NA Homo sapiens
TAX032407
GO:1902187 biological process negative regulation of viral release from host cell Any process that stops, prevents or reduces the frequency, rate or extent of viral release from host (more detail) 15 NA Homo sapiens
IEI011434
Protein protein interactors of human gene RNF25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF25 (SwissProt ID= (more detail) 15 17535438 Homo sapiens
TAX017776
GO:0009812 biological process flavonoid metabolic process The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivati (more detail) 15 NA Homo sapiens
TAX021890
GO:0032958 biological process inositol phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6 (more detail) 13 NA Homo sapiens
TAX026083
GO:0048188 cellular component Set1C/COMPASS complex A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex c (more detail) 13 NA Homo sapiens
TAX001273
Genes annotated by the GO term GO:0019201. Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate. (more detail) 13 NA Homo sapiens
WIG000624
Sulfur metabolism (more detail) 13 NA Homo sapiens
MOX003413
Genes associated with Computational Drug Signature NVP AEW541 Genes associated with Computational Drug Signature NVP-AEW541, curated by the Drug Signature Databas (more detail) 16 25990557 Homo sapiens
WAG000423
human cytomegalovirus and map kinase pathways To replicate in the host cell, viruses commandeer cellular sigling pathways. Cytomegalovirus (CMV) i (more detail) 16 NA Homo sapiens
TAX023483
GO:0038084 biological process vascular endothelial growth factor signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF (more detail) 16 NA Homo sapiens
TAX001266
Genes annotated by the GO term GO:0004715. Catalysis of the reaction: ATP + a protein L tyrosine = ADP + a protein L tyrosine phosphate. (more detail) 11 NA Homo sapiens
TAX013710
GO:0001574 biological process ganglioside biosynthetic process The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying (more detail) 9 NA Homo sapiens
TAX015240
GO:0004579 molecular function dolichyl diphosphooligosaccharide protein glycotransferase activity Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl dipho (more detail) 9 NA Homo sapiens
PEX001660
HECT: HECT domain (ubiquitin transferase) The name HECT comes from Homologous to the E6-AP Carboxyl Terminus. (more detail) 9 NA Homo sapiens
MOX012197
Genes associated with Computational Drug Signature Debromohymenialdisine Genes associated with Computational Drug Signature Debromohymenialdisine, curated by the Drug Signat (more detail) 9 25990557 Homo sapiens
MEX001260
Genes associated with Kinase Inhibitor Sunitinib Genes associated with Kinase Inhibitor Sunitinib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002218
Genes associated with Kinase Inhibitor BX 517 Genes associated with Kinase Inhibitor BX-517, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002000
Genes associated with Kinase Inhibitor CHEMBL1993941 Genes associated with Kinase Inhibitor CHEMBL1993941, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MEX001823
Genes associated with Kinase Inhibitor GW843682X Genes associated with Kinase Inhibitor GW843682X, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MOX001138
Genes associated with Computational Drug Signature 4 Hydroxyestrone Genes associated with Computational Drug Signature 4-Hydroxyestrone, curated by the Drug Signature D (more detail) 9 25990557 Homo sapiens
MOX013420
Genes associated with Computational Drug Signature leucettamine B Genes associated with Computational Drug Signature leucettamine B, curated by the Drug Signature Dat (more detail) 9 25990557 Homo sapiens
PEX001840
EphA2 TM: Ephrin type A receptor 2 transmembrane domain Epha2_TM represents the left-handed dimer transmembrane domain of of EphA2 receptor. This domain ol (more detail) 9 NA Homo sapiens
PEX002570
zf RING 2: Ring finger domain (more detail) 9 NA Homo sapiens
TAX001241
Genes annotated by the GO term GO:0004709. Catalysis of the phosphorylation and activation of MAP kinase kinases; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases. (more detail) 9 NA Homo sapiens
MEX001403
Genes associated with Kinase Inhibitor NCGC00346961 01 Genes associated with Kinase Inhibitor NCGC00346961-01, curated by the Drug Signature Database (DSig (more detail) 9 25990557 Homo sapiens
MEX002033
Genes associated with Kinase Inhibitor Sorafenib Genes associated with Kinase Inhibitor Sorafenib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002183
Genes associated with Kinase Inhibitor PDGF Receptor Tyrosine Kinase Inhibitor V Genes associated with Kinase Inhibitor PDGF Receptor Tyrosine Kinase Inhibitor V, curated by the Dru (more detail) 9 25990557 Homo sapiens
MEX001449
Genes associated with Kinase Inhibitor CHEMBL47203 Genes associated with Kinase Inhibitor CHEMBL47203, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001253
Genes associated with Kinase Inhibitor Kinome 242 Genes associated with Kinase Inhibitor Kinome_242, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001049
Genes associated with Approved Drug sunitinib malate Genes associated with Approved Drug sunitinib malate, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
TAX014794
GO:0003810 molecular function protein glutamine gamma glutamyltransferase activity Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This re (more detail) 9 NA Homo sapiens
MEX001372
Genes associated with Kinase Inhibitor Kinome 1335 Genes associated with Kinase Inhibitor Kinome_1335, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001380
Genes associated with Kinase Inhibitor lfm a13 Genes associated with Kinase Inhibitor lfm-a13, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002310
Genes associated with Kinase Inhibitor Tozasertib Genes associated with Kinase Inhibitor Tozasertib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001901
Genes associated with Kinase Inhibitor Kinome 709 Genes associated with Kinase Inhibitor Kinome_709, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002231
Genes associated with Kinase Inhibitor 1 NM PP1 Genes associated with Kinase Inhibitor 1-NM-PP1, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002078
Genes associated with Kinase Inhibitor Kinome 2052 Genes associated with Kinase Inhibitor Kinome_2052, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001793
Genes associated with Kinase Inhibitor CHEMBL1979577 Genes associated with Kinase Inhibitor CHEMBL1979577, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MEX002121
Genes associated with Kinase Inhibitor CHEMBL2062937 Genes associated with Kinase Inhibitor CHEMBL2062937, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MEX002147
Genes associated with Kinase Inhibitor CHEMBL1979883 Genes associated with Kinase Inhibitor CHEMBL1979883, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MEX002191
Genes associated with Kinase Inhibitor CHEMBL241517 Genes associated with Kinase Inhibitor CHEMBL241517, curated by the Drug Signature Database (DSigDB) (more detail) 9 25990557 Homo sapiens
TAX014916
GO:0004017 molecular function adenylate kinase activity Catalysis of the reaction: ATP + AMP = 2 ADP. (more detail) 9 NA Homo sapiens
GEX000594
dna dna associated genes. PAGER constructed this gene set by grouping all genes which are associated wit (more detail) 9 NA Homo sapiens
MEX001354
Genes associated with Kinase Inhibitor Dasatinib Genes associated with Kinase Inhibitor Dasatinib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001563
Genes associated with Kinase Inhibitor Kinome 2079 Genes associated with Kinase Inhibitor Kinome_2079, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002068
Genes associated with Kinase Inhibitor BX 320 Genes associated with Kinase Inhibitor BX-320, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002119
Genes associated with Kinase Inhibitor GW809897X Genes associated with Kinase Inhibitor GW809897X, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
PEX002198
GST C 3: Glutathione S transferase, C terminal domain This domain is closely related to Pfam:PF00043. (more detail) 9 NA Homo sapiens
WAG000332
mRNA Processing (more detail) 9 NA Homo sapiens
MEX001289
Genes associated with Kinase Inhibitor SU11274 Genes associated with Kinase Inhibitor SU11274, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001911
Genes associated with Kinase Inhibitor ML 9 Genes associated with Kinase Inhibitor ML-9, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MOX007345
Genes associated with Computational Drug Signature BMS 754807 Genes associated with Computational Drug Signature BMS-754807, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens
TAX013597
GO:0001054 molecular function RNA polymerase I activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA (more detail) 9 NA Homo sapiens
MEX001433
Genes associated with Kinase Inhibitor S1107 Selleck Genes associated with Kinase Inhibitor S1107_Selleck, curated by the Drug Signature Database (DSigDB (more detail) 9 25990557 Homo sapiens
MEX001374
Genes associated with Kinase Inhibitor CHEMBL411903 Genes associated with Kinase Inhibitor CHEMBL411903, curated by the Drug Signature Database (DSigDB) (more detail) 9 25990557 Homo sapiens
MEX001377
Genes associated with Kinase Inhibitor Kinome 468 Genes associated with Kinase Inhibitor Kinome_468, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001887
Genes associated with Kinase Inhibitor aminopurvalanol A Genes associated with Kinase Inhibitor aminopurvalanol A, curated by the Drug Signature Database (DS (more detail) 9 25990557 Homo sapiens
MEX001682
Genes associated with Kinase Inhibitor 7 Hydroxystaurosporine Genes associated with Kinase Inhibitor 7-Hydroxystaurosporine, curated by the Drug Signature Databas (more detail) 9 25990557 Homo sapiens
MEX002402
Genes associated with Kinase Inhibitor Lapatinib Genes associated with Kinase Inhibitor Lapatinib, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX002104
Genes associated with Kinase Inhibitor PF 477736 Genes associated with Kinase Inhibitor PF-477736, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
TAX015558
GO:0005024 molecular function transforming growth factor beta activated receptor activity Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side (more detail) 9 NA Homo sapiens
TAX015321
GO:0004690 molecular function cyclic nucleotide dependent protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the pres (more detail) 9 NA Homo sapiens
MAX002047
Composition of the 2 MDa human PCAF complex. Transcription in eukaryotes is a tightly regulated, multistep process. Gene-specific transcriptional (more detail) 9 NA Homo sapiens
TAX000764
Genes annotated by the GO term GO:0030148. The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long chain amine diol sphingosine or a closely related base (a sphingoid). (more detail) 9 NA Homo sapiens
MEX001398
Genes associated with Kinase Inhibitor JNK Inhibitor V Genes associated with Kinase Inhibitor JNK Inhibitor V, curated by the Drug Signature Database (DSig (more detail) 9 25990557 Homo sapiens
MEX001888
Genes associated with Kinase Inhibitor Oxindole Based Inhibitor 54 Genes associated with Kinase Inhibitor Oxindole-Based Inhibitor 54, curated by the Drug Signature Da (more detail) 9 25990557 Homo sapiens
MEX001691
Genes associated with Kinase Inhibitor Kinome 413 Genes associated with Kinase Inhibitor Kinome_413, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX001211
Genes associated with Kinase Inhibitor purvalanol A Genes associated with Kinase Inhibitor purvalanol A, curated by the Drug Signature Database (DSigDB) (more detail) 9 25990557 Homo sapiens
TAX023754
GO:0042285 molecular function xylosyltransferase activity Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate (more detail) 9 NA Homo sapiens
TAX027430
GO:0052696 biological process flavonoid glucuronidation The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucu (more detail) 9 NA Homo sapiens
TAX025842
GO:0046972 molecular function histone acetyltransferase activity (H4 K16 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acet (more detail) 9 NA Homo sapiens
TAX024562
GO:0043995 molecular function histone acetyltransferase activity (H4 K5 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acety (more detail) 9 NA Homo sapiens
TAX017104
GO:0008174 molecular function mRNA methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in (more detail) 9 NA Homo sapiens
TAX025880
GO:0047144 molecular function 2 acylglycerol 3 phosphate O acyltransferase activity Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA. (more detail) 9 NA Homo sapiens
TAX023789
GO:0042355 biological process L fucose catabolic process The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose). (more detail) 9 NA Homo sapiens
TAX022781
GO:0035252 molecular function UDP xylosyltransferase activity Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule. (more detail) 9 NA Homo sapiens
TAX024563
GO:0043996 molecular function histone acetyltransferase activity (H4 K8 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acety (more detail) 9 NA Homo sapiens
TAX020953
GO:0031371 cellular component ubiquitin conjugating enzyme complex Any complex that possesses ubiquitin conjugating enzyme activity. (more detail) 9 NA Homo sapiens
IEI011435
Protein protein interactors of human gene RNF26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF26 (SwissProt ID= (more detail) 9 17535438 Homo sapiens
TAX019674
GO:0019317 biological process fucose catabolic process The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose). (more detail) 9 NA Homo sapiens
TAX023788
GO:0042354 biological process L fucose metabolic process The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in (more detail) 9 NA Homo sapiens
TAX022780
GO:0035251 molecular function UDP glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule. (more detail) 9 NA Homo sapiens
IEI005910
Protein protein interactors of human gene HMGN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HMGN2 (SwissProt ID= (more detail) 14 17535438 Homo sapiens
IEI012133
Protein protein interactors of human gene SH2B1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SH2B1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens
TAX017528
GO:0009130 biological process pyrimidine nucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphat (more detail) 14 NA Homo sapiens
IEI011375
Protein protein interactors of human gene RNF103 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF103 (SwissProt ID (more detail) 14 17535438 Homo sapiens
IEI001350
Protein protein interactors of human gene BIRC8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BIRC8 (SwissProt ID= (more detail) 14 17535438 Homo sapiens
TAX022674
GO:0034969 biological process histone arginine methylation The modification of a histone by addition of a methyl group to an arginine residue. (more detail) 12 NA Homo sapiens
TAX022860
GO:0035404 biological process histone serine phosphorylation The modification of histones by addition of a phosphate group to a serine residue. (more detail) 12 NA Homo sapiens
IEI012174
Protein protein interactors of human gene SHC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SHC2 (SwissProt ID=P (more detail) 12 17535438 Homo sapiens
IEI003378
Protein protein interactors of human gene DCUN1D3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCUN1D3 (SwissProt I (more detail) 12 17535438 Homo sapiens
IEI011402
Protein protein interactors of human gene RNF150 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF150 (SwissProt ID (more detail) 12 17535438 Homo sapiens
IEI014170
Protein protein interactors of human gene TRAF7 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRAF7 (SwissProt ID= (more detail) 12 17535438 Homo sapiens
TAX024153
GO:0043097 biological process pyrimidine nucleoside salvage Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting (more detail) 12 NA Homo sapiens
TAX017394
GO:0008655 biological process pyrimidine containing compound salvage Any process that generates a pyrimidine-containing compound, any nucleobase, nucleoside, nucleotide (more detail) 12 NA Homo sapiens
PEX002387
FGF: Fibroblast growth factor Fibroblast growth factors are a family of proteins involved in growth and differentiation in a wide (more detail) 12 NA Homo sapiens
MOX012423
Genes associated with Computational Drug Signature Doramapimod Genes associated with Computational Drug Signature Doramapimod, curated by the Drug Signature Databa (more detail) 15 25990557 Homo sapiens
FEX001587
Leukemia Sanchez Guijo08 15genes SuppTable2m Genes related to the ubiquitination process (more detail) 15 18722011 Homo sapiens
WIG001131
Genes involved in Regulation of AMPK activity via LKB1 (more detail) 15 NA Homo sapiens
WIG000628
Terpenoid backbone biosynthesis (more detail) 15 NA Homo sapiens
TAX017527
GO:0009129 biological process pyrimidine nucleoside monophosphate metabolic process The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consis (more detail) 15 NA Homo sapiens
TAX020991
GO:0031434 molecular function mitogen activated protein kinase kinase binding Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any prote (more detail) 15 NA Homo sapiens
TAX024554
GO:0043982 biological process histone H4 K8 acetylation The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 (more detail) 15 NA Homo sapiens
IEI010237
Protein protein interactors of human gene POLR3G from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POLR3G (SwissProt ID (more detail) 15 17535438 Homo sapiens
IEI013079
Protein protein interactors of human gene STAP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAP2 (SwissProt ID= (more detail) 15 17535438 Homo sapiens
IEI003117
Protein protein interactors of human gene CTLA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CTLA4 (SwissProt ID= (more detail) 15 17535438 Homo sapiens
TAX024553
GO:0043981 biological process histone H4 K5 acetylation The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 (more detail) 15 NA Homo sapiens
TAX025413
GO:0046049 biological process UMP metabolic process The chemical reactions and pathways involving UMP, uridine monophosphate. (more detail) 10 NA Homo sapiens
TAX020412
GO:0030259 biological process lipid glycosylation Covalent attachment of a glycosyl residue to a lipid molecule. (more detail) 10 NA Homo sapiens
TAX020976
GO:0031414 cellular component N terminal protein acetyltransferase complex A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acce (more detail) 10 NA Homo sapiens
TAX017568
GO:0009173 biological process pyrimidine ribonucleoside monophosphate metabolic process The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound co (more detail) 10 NA Homo sapiens
TAX017569
GO:0009174 biological process pyrimidine ribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophos (more detail) 10 NA Homo sapiens
IEI015829
Protein protein interactors of human gene ZNRF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNRF4 (SwissProt ID= (more detail) 10 17535438 Homo sapiens
MOX007171
Genes associated with Computational Drug Signature balanol Genes associated with Computational Drug Signature balanol, curated by the Drug Signature Database ( (more detail) 10 25990557 Homo sapiens
MOX005477
Genes associated with Computational Drug Signature 10Z Hymenialdisine Genes associated with Computational Drug Signature 10Z-Hymenialdisine, curated by the Drug Signature (more detail) 10 25990557 Homo sapiens
MOX013460
Genes associated with Computational Drug Signature Linifanib Genes associated with Computational Drug Signature Linifanib, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
WIG000951
Genes involved in IRAK1 recruits IKK complex (more detail) 10 NA Homo sapiens
TAX000998
Genes annotated by the GO term GO:0008250. A multisubunit protein complex in the endoplasmic reticulum membrane of eukaryotes that transfers lipid linked oligosaccharide precursor to asparagine residues on nascent proteins; includes at least nine different subunits, at least in yeast. (more detail) 10 NA Homo sapiens
MOX014386
Genes associated with Computational Drug Signature PD 0183812 Genes associated with Computational Drug Signature PD-0183812, curated by the Drug Signature Databas (more detail) 10 25990557 Homo sapiens
TAX016197
GO:0006222 biological process UMP biosynthetic process The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate. (more detail) 10 NA Homo sapiens
TAX029007
GO:0070567 molecular function cytidylyltransferase activity Catalysis of the transfer of a cytidylyl group to an acceptor. (more detail) 8 NA Homo sapiens
TAX017290
GO:0008469 molecular function histone arginine N methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine (more detail) 8 NA Homo sapiens
TAX023318
GO:0036289 biological process peptidyl serine autophosphorylation The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine r (more detail) 8 NA Homo sapiens
TAX019019
GO:0016427 molecular function tRNA (cytosine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA contain (more detail) 8 NA Homo sapiens
TAX030195
GO:0085020 biological process protein K6 linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine (more detail) 8 NA Homo sapiens
TAX019007
GO:0016413 molecular function O acetyltransferase activity Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule. (more detail) 8 NA Homo sapiens
TAX019189
GO:0016742 molecular function hydroxymethyl , formyl and related transferase activity Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another ( (more detail) 8 NA Homo sapiens
TAX025809
GO:0046920 molecular function alpha (1 >3) fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to fo (more detail) 8 NA Homo sapiens
TAX019422
GO:0017169 molecular function CDP alcohol phosphatidyltransferase activity Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol. (more detail) 8 NA Homo sapiens
MEX001661
Genes associated with Kinase Inhibitor CGP 57380 Genes associated with Kinase Inhibitor CGP 57380, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
PEX001107
Acetyltransf 1: Acetyltransferase (GNAT) family This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. (more detail) 8 NA Homo sapiens
PEX000706
PI3 PI4 kinase: Phosphatidylinositol 3 and 4 kinase Some members of this family probably do not have lipid kinase activity and are protein kinases, e.g. (more detail) 8 NA Homo sapiens
MOX011633
Genes associated with Computational Drug Signature CHEMBL608532 Genes associated with Computational Drug Signature CHEMBL608532, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens
MOX014852
Genes associated with Computational Drug Signature ro 32 0432 Genes associated with Computational Drug Signature ro 32-0432, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
MEX001406
Genes associated with Kinase Inhibitor CHEMBL1967720 Genes associated with Kinase Inhibitor CHEMBL1967720, curated by the Drug Signature Database (DSigDB (more detail) 8 25990557 Homo sapiens
MEX001319
Genes associated with Kinase Inhibitor CHEMBL592030 Genes associated with Kinase Inhibitor CHEMBL592030, curated by the Drug Signature Database (DSigDB) (more detail) 8 25990557 Homo sapiens
MEX001338
Genes associated with Kinase Inhibitor 5Z 7 Oxozeaenol Genes associated with Kinase Inhibitor 5Z-7-Oxozeaenol, curated by the Drug Signature Database (DSig (more detail) 8 25990557 Homo sapiens
MEX001547
Genes associated with Kinase Inhibitor 732983 37 8 Genes associated with Kinase Inhibitor 732983-37-8, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX002242
Genes associated with Kinase Inhibitor Kinome 3566 Genes associated with Kinase Inhibitor Kinome_3566, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001480
Genes associated with Kinase Inhibitor Src Kinase Inhibitor I Genes associated with Kinase Inhibitor Src Kinase Inhibitor I, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
MEX001609
Genes associated with Kinase Inhibitor 2zv2 Genes associated with Kinase Inhibitor 2zv2, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001462
Genes associated with Kinase Inhibitor SU9516 Genes associated with Kinase Inhibitor SU9516, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX002140
Genes associated with Kinase Inhibitor Vatalanib Genes associated with Kinase Inhibitor Vatalanib, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
PEX002015
Ephrin lbd: Ephrin receptor ligand binding domain The Eph receptors, which bind to ephrins Pfam:PF00812 are a large family of receptor tyrosine kinase (more detail) 8 NA Homo sapiens
MEX002316
Genes associated with Kinase Inhibitor GW693917A Genes associated with Kinase Inhibitor GW693917A, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX002272
Genes associated with Kinase Inhibitor Kinome 876 Genes associated with Kinase Inhibitor Kinome_876, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX002300
Genes associated with Kinase Inhibitor GSK619487A Genes associated with Kinase Inhibitor GSK619487A, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001489
Genes associated with Kinase Inhibitor Kinome 458 Genes associated with Kinase Inhibitor Kinome_458, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MOX009479
Genes associated with Computational Drug Signature CHEMBL292495 Genes associated with Computational Drug Signature CHEMBL292495, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens
MOX015639
Genes associated with Computational Drug Signature Triphenylacrylonitrile Genes associated with Computational Drug Signature Triphenylacrylonitrile, curated by the Drug Signa (more detail) 8 25990557 Homo sapiens
MEX001241
Genes associated with Kinase Inhibitor Kinome 77 Genes associated with Kinase Inhibitor Kinome_77, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001541
Genes associated with Kinase Inhibitor Bay 65 1942 hydrochloride Genes associated with Kinase Inhibitor Bay 65-1942 hydrochloride, curated by the Drug Signature Data (more detail) 8 25990557 Homo sapiens
MEX001920
Genes associated with Kinase Inhibitor GW784307A Genes associated with Kinase Inhibitor GW784307A, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001627
Genes associated with Kinase Inhibitor GW770249X Genes associated with Kinase Inhibitor GW770249X, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001470
Genes associated with Kinase Inhibitor Kinome 258 Genes associated with Kinase Inhibitor Kinome_258, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
TAX016359
GO:0006477 biological process protein sulfation The addition of a sulfate group as an ester to a protein amino acid. (more detail) 8 NA Homo sapiens
MEX001325
Genes associated with Kinase Inhibitor Kinome 463 Genes associated with Kinase Inhibitor Kinome_463, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX002309
Genes associated with Kinase Inhibitor Kinome 203 Genes associated with Kinase Inhibitor Kinome_203, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX001586
Genes associated with Kinase Inhibitor Cdk4 Inhibitor Genes associated with Kinase Inhibitor Cdk4 Inhibitor, curated by the Drug Signature Database (DSigD (more detail) 8 25990557 Homo sapiens
MEX001975
Genes associated with Kinase Inhibitor 1173900 33 8 Genes associated with Kinase Inhibitor 1173900-33-8, curated by the Drug Signature Database (DSigDB) (more detail) 8 25990557 Homo sapiens
MEX002351
Genes associated with Kinase Inhibitor 406209 26 5 Genes associated with Kinase Inhibitor 406209-26-5, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
TAX017198
GO:0008318 molecular function protein prenyltransferase activity Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group (more detail) 8 NA Homo sapiens
MEX001264
Genes associated with Kinase Inhibitor SB 747651A Genes associated with Kinase Inhibitor SB-747651A, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MEX002257
Genes associated with Kinase Inhibitor 4 anilinopyrimidine 8c Genes associated with Kinase Inhibitor 4-anilinopyrimidine 8c, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
MEX001657
Genes associated with Kinase Inhibitor Kinome 3177 Genes associated with Kinase Inhibitor Kinome_3177, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
TAX014802
GO:0003831 molecular function beta N acetylglucosaminylglycopeptide beta 1,4 galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-g (more detail) 8 NA Homo sapiens
TAX015546
GO:0005005 molecular function transmembrane ephrin receptor activity Combining with a transmembrane ephrin to initiate a change in cell activity. (more detail) 8 NA Homo sapiens
IEI009745
Protein protein interactors of human gene PELI3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PELI3 (SwissProt ID= (more detail) 13 17535438 Homo sapiens
IEI003377
Protein protein interactors of human gene DCUN1D2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCUN1D2 (SwissProt I (more detail) 13 17535438 Homo sapiens
IEI014257
Protein protein interactors of human gene TRIM50 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM50 (SwissProt ID (more detail) 13 17535438 Homo sapiens
IEI014580
Protein protein interactors of human gene UBE2J2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBE2J2 (SwissProt ID (more detail) 13 17535438 Homo sapiens
TAX031998
GO:1901070 biological process guanosine containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (gu (more detail) 13 NA Homo sapiens
IEI003982
Protein protein interactors of human gene EFNA5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFNA5 (SwissProt ID= (more detail) 13 17535438 Homo sapiens
WIG000278
CBL mediated ligand induced downregulation of EGF receptors As with many cell-surface receptors, activation of the EGF receptor can result in receptor internali (more detail) 13 NA Homo sapiens
MOX001119
Genes associated with Computational Drug Signature 15(S) HETE d8 Genes associated with Computational Drug Signature 15(S)-HETE-d8, curated by the Drug Signature Data (more detail) 11 25990557 Homo sapiens
TAX016175
GO:0006183 biological process GTP biosynthetic process The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate. (more detail) 11 NA Homo sapiens
MOX001108
Genes associated with Computational Drug Signature Arsenic acid Genes associated with Computational Drug Signature Arsenic acid, curated by the Drug Signature Datab (more detail) 11 25990557 Homo sapiens
WAG000299
Gab1 signalosome (more detail) 11 NA Homo sapiens
IEI001403
Protein protein interactors of human gene BORA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BORA (SwissProt ID=Q (more detail) 9 17535438 Homo sapiens
TAX017531
GO:0009133 biological process nucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compou (more detail) 9 NA Homo sapiens
IEI004989
Protein protein interactors of human gene GAB3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GAB3 (SwissProt ID=Q (more detail) 9 17535438 Homo sapiens
MOX015748
Genes associated with Computational Drug Signature UNII J8AY0Z4CBP Genes associated with Computational Drug Signature UNII-J8AY0Z4CBP, curated by the Drug Signature Da (more detail) 9 25990557 Homo sapiens
WAG001128
Processive synthesis on the lagging strand (more detail) 9 NA Homo sapiens
WAG000293
Leading Strand Synthesis (more detail) 9 NA Homo sapiens
WAG000888
Lagging Strand Synthesis (more detail) 9 NA Homo sapiens
MOX014196
Genes associated with Computational Drug Signature nu6102 Genes associated with Computational Drug Signature nu6102, curated by the Drug Signature Database (D (more detail) 9 25990557 Homo sapiens
WAG001548
Telomere C strand (Lagging Strand) Synthesis (more detail) 9 NA Homo sapiens
WAG000285
DNA strand elongation (more detail) 9 NA Homo sapiens
TAX031526
GO:0102756 molecular function very long chain 3 ketoacyl CoA synthase activity Catalysis of the reaction: malonyl-CoA + a very-long-chain 2,3,4-saturated fatty acyl CoA = carbon d (more detail) 7 NA Homo sapiens
TAX031491
GO:0102337 molecular function 3 oxo cerotoyl CoA synthase activity Catalysis of the reaction: tetracosanoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxohexacosanoyl-CoA + (more detail) 7 NA Homo sapiens
TAX022567
GO:0034626 biological process fatty acid elongation, polyunsaturated fatty acid Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced. (more detail) 7 NA Homo sapiens
TAX018969
GO:0016308 molecular function 1 phosphatidylinositol 4 phosphate 5 kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo- (more detail) 7 NA Homo sapiens
TAX022691
GO:0035005 molecular function 1 phosphatidylinositol 4 phosphate 3 kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo- (more detail) 7 NA Homo sapiens
TAX019497
GO:0018211 biological process peptidyl tryptophan modification The chemical alteration of a tryptophan residue in a peptide. (more detail) 7 NA Homo sapiens
TAX020450
GO:0030309 biological process poly N acetyllactosamine metabolic process The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N (more detail) 7 NA Homo sapiens
TAX017808
GO:0009922 molecular function fatty acid elongase activity Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C). (more detail) 7 NA Homo sapiens
TAX019518
GO:0018317 biological process protein C linked glycosylation via tryptophan The glycosylation of a carbon atom of a peptidyl-tryptophan residue. (more detail) 7 NA Homo sapiens
TAX019884
GO:0019919 biological process peptidyl arginine methylation, to asymmetrical dimethyl arginine The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-argini (more detail) 7 NA Homo sapiens
TAX017102
GO:0008172 molecular function S methyltransferase activity Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule. (more detail) 7 NA Homo sapiens
TAX019459
GO:0018103 biological process protein C linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to (more detail) 7 NA Homo sapiens
TAX022861
GO:0035405 biological process histone threonine phosphorylation The modification of histones by addition of a phosphate group to a threonine residue. (more detail) 7 NA Homo sapiens
TAX022566
GO:0034625 biological process fatty acid elongation, monounsaturated fatty acid Elongation of a fatty acid chain into which one C-C double bond has been introduced. (more detail) 7 NA Homo sapiens
TAX019696
GO:0019368 biological process fatty acid elongation, unsaturated fatty acid Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced. (more detail) 7 NA Homo sapiens
TAX029009
GO:0070569 molecular function uridylyltransferase activity Catalysis of the transfer of an uridylyl group to an acceptor. (more detail) 7 NA Homo sapiens
TAX017296
GO:0008479 molecular function queuine tRNA ribosyltransferase activity Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine. (more detail) 7 NA Homo sapiens
TAX022773
GO:0035242 molecular function protein arginine omega N asymmetric methyltransferase activity Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is o (more detail) 7 NA Homo sapiens
TAX031492
GO:0102338 molecular function 3 oxo lignoceronyl CoA synthase activity Catalysis of the reaction: behenoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxotetracosanoyl-CoA. + car (more detail) 7 NA Homo sapiens
TAX019535
GO:0018406 biological process protein C linked glycosylation via 2' alpha mannosyl L tryptophan The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolic (more detail) 7 NA Homo sapiens
TAX019505
GO:0018243 biological process protein O linked glycosylation via threonine The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; (more detail) 7 NA Homo sapiens
TAX019695
GO:0019367 biological process fatty acid elongation, saturated fatty acid Elongation of a saturated fatty acid chain. (more detail) 7 NA Homo sapiens
TAX017289
GO:0008467 molecular function [heparan sulfate] glucosamine 3 sulfotransferase 1 activity Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3' (more detail) 7 NA Homo sapiens
TAX031490
GO:0102336 molecular function 3 oxo arachidoyl CoA synthase activity Catalysis of the reaction: stearoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxoicosanoyl-CoA. + carbon (more detail) 7 NA Homo sapiens
TAX017272
GO:0008443 molecular function phosphofructokinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a phosphofructose substrate mol (more detail) 7 NA Homo sapiens
TAX022755
GO:0035184 molecular function histone threonine kinase activity Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any (more detail) 7 NA Homo sapiens
MEX001693
Genes associated with Kinase Inhibitor Kinome 421 Genes associated with Kinase Inhibitor Kinome_421, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX013193
Genes associated with Computational Drug Signature isogranulatimide Genes associated with Computational Drug Signature isogranulatimide, curated by the Drug Signature D (more detail) 7 25990557 Homo sapiens
TAX015055
GO:0004321 molecular function fatty acyl CoA synthase activity Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain ac (more detail) 7 NA Homo sapiens
TAX015545
GO:0005004 molecular function GPI linked ephrin receptor activity Combining with a GPI-anchored ephrin to initiate a change in cell activity. (more detail) 7 NA Homo sapiens
TAX015557
GO:0005021 molecular function vascular endothelial growth factor activated receptor activity Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the pl (more detail) 7 NA Homo sapiens
TAX015322
GO:0004691 molecular function cAMP dependent protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the pres (more detail) 7 NA Homo sapiens
PEX001128
Methyltransf 23: Methyltransferase domain This family appears to be a methyltransferase domain. (more detail) 7 NA Homo sapiens
MOX011750
Genes associated with Computational Drug Signature CHEMBL76100 Genes associated with Computational Drug Signature CHEMBL76100, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX014469
Genes associated with Computational Drug Signature Phenol, 4,4' (3 methyl 1 butenylidene)bis Genes associated with Computational Drug Signature Phenol, 4,4'-(3-methyl-1-butenylidene)bis-, curat (more detail) 7 25990557 Homo sapiens
MEX001611
Genes associated with Kinase Inhibitor Kinome 125 Genes associated with Kinase Inhibitor Kinome_125, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002282
Genes associated with Kinase Inhibitor Akt inhibitor VIII Genes associated with Kinase Inhibitor Akt inhibitor VIII, curated by the Drug Signature Database (D (more detail) 7 25990557 Homo sapiens
MEX001808
Genes associated with Kinase Inhibitor TG003 Genes associated with Kinase Inhibitor TG003, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001824
Genes associated with Kinase Inhibitor Kinome 575 Genes associated with Kinase Inhibitor Kinome_575, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX006051
Genes associated with Computational Drug Signature 4 cycloheptyliden(4 hydroxyphenyl)methylphenol Genes associated with Computational Drug Signature 4-cycloheptyliden(4-hydroxyphenyl)methylphenol, c (more detail) 7 25990557 Homo sapiens
MOX013239
Genes associated with Computational Drug Signature JNJ 10198409 Genes associated with Computational Drug Signature JNJ-10198409, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
TAX016503
GO:0006657 biological process CDP choline pathway The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and end (more detail) 7 NA Homo sapiens
TAX013671
GO:0001517 molecular function N acetylglucosamine 6 O sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosin (more detail) 7 NA Homo sapiens
PEX001617
Cullin: Cullin family (more detail) 7 NA Homo sapiens
MEX001245
Genes associated with Kinase Inhibitor Kinome 131 Genes associated with Kinase Inhibitor Kinome_131, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001322
Genes associated with Kinase Inhibitor CHEMBL189231 Genes associated with Kinase Inhibitor CHEMBL189231, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens
MEX001608
Genes associated with Kinase Inhibitor Kinome 332 Genes associated with Kinase Inhibitor Kinome_332, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002157
Genes associated with Kinase Inhibitor Kinome 2847 Genes associated with Kinase Inhibitor Kinome_2847, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX006363
Genes associated with Computational Drug Signature 722544 51 6 Genes associated with Computational Drug Signature 722544-51-6, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX005843
Genes associated with Computational Drug Signature 3 (4 Hydroxy phenyl) 2,3 diphenyl acrylonitrile Genes associated with Computational Drug Signature 3-(4-Hydroxy-phenyl)-2,3-diphenyl-acrylonitrile, (more detail) 7 25990557 Homo sapiens
MOX011199
Genes associated with Computational Drug Signature CHEMBL538718 Genes associated with Computational Drug Signature CHEMBL538718, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
MEX001936
Genes associated with Kinase Inhibitor SU 5416 Genes associated with Kinase Inhibitor SU 5416, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001792
Genes associated with Kinase Inhibitor GSK994854A Genes associated with Kinase Inhibitor GSK994854A, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001494
Genes associated with Kinase Inhibitor EGFR/ErbB 2/ErbB 4 Inhibitor Genes associated with Kinase Inhibitor EGFR/ErbB-2/ErbB-4 Inhibitor, curated by the Drug Signature D (more detail) 7 25990557 Homo sapiens
MEX001845
Genes associated with Kinase Inhibitor Lapatinib Genes associated with Kinase Inhibitor Lapatinib, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX006664
Genes associated with Computational Drug Signature AGN PC 001QK8 Genes associated with Computational Drug Signature AGN-PC-001QK8, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens
TAX017916
GO:0010452 biological process histone H3 K36 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of (more detail) 7 NA Homo sapiens
TAX015289
GO:0004645 molecular function phosphorylase activity Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D (more detail) 7 NA Homo sapiens
TAX015316
GO:0004679 molecular function AMP activated protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the pres (more detail) 7 NA Homo sapiens
MEX002258
Genes associated with Kinase Inhibitor GW795486X Genes associated with Kinase Inhibitor GW795486X, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002291
Genes associated with Kinase Inhibitor CHEMBL188268 Genes associated with Kinase Inhibitor CHEMBL188268, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens
MEX002065
Genes associated with Kinase Inhibitor Kinome 1078 Genes associated with Kinase Inhibitor Kinome_1078, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001754
Genes associated with Kinase Inhibitor Kinome 471 Genes associated with Kinase Inhibitor Kinome_471, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001870
Genes associated with Kinase Inhibitor CHEMBL458415 Genes associated with Kinase Inhibitor CHEMBL458415, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens
MOX006666
Genes associated with Computational Drug Signature AGN PC 001QKE Genes associated with Computational Drug Signature AGN-PC-001QKE, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens
MOX009490
Genes associated with Computational Drug Signature CHEMBL294120 Genes associated with Computational Drug Signature CHEMBL294120, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
MOX015778
Genes associated with Computational Drug Signature UNII ZZ6VH5MZ17 Genes associated with Computational Drug Signature UNII-ZZ6VH5MZ17, curated by the Drug Signature Da (more detail) 7 25990557 Homo sapiens
MOX014637
Genes associated with Computational Drug Signature Prostratin Genes associated with Computational Drug Signature Prostratin, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
MEX001916
Genes associated with Kinase Inhibitor (E) N Methyl 2 ((3 (2 (pyridin 2 yl)vinyl) 1H indazol 6 yl)thio)benzamide Genes associated with Kinase Inhibitor (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)th (more detail) 7 25990557 Homo sapiens
MEX001607
Genes associated with Kinase Inhibitor Kinome 41 Genes associated with Kinase Inhibitor Kinome_41, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001619
Genes associated with Kinase Inhibitor GW410563A Genes associated with Kinase Inhibitor GW410563A, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002271
Genes associated with Kinase Inhibitor Oxindole Based Inhibitor 80 Genes associated with Kinase Inhibitor Oxindole-Based Inhibitor 80, curated by the Drug Signature Da (more detail) 7 25990557 Homo sapiens
MOX011736
Genes associated with Computational Drug Signature CHEMBL73495 Genes associated with Computational Drug Signature CHEMBL73495, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX012111
Genes associated with Computational Drug Signature Cyclofenil diphenol Genes associated with Computational Drug Signature Cyclofenil diphenol, curated by the Drug Signatur (more detail) 7 25990557 Homo sapiens
MEX001256
Genes associated with Kinase Inhibitor 1 [4 (4 amino 6 methylthieno[2,3 d]pyrimidin 5 yl)phenyl] 3 (3,5 dimethylphenyl)urea Genes associated with Kinase Inhibitor 1-[4-(4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl)phenyl]-3-( (more detail) 7 25990557 Homo sapiens
MEX001540
Genes associated with Kinase Inhibitor GW300660X Genes associated with Kinase Inhibitor GW300660X, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001877
Genes associated with Kinase Inhibitor CHEMBL508928 Genes associated with Kinase Inhibitor CHEMBL508928, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens
MEX001614
Genes associated with Kinase Inhibitor Kinome 245 Genes associated with Kinase Inhibitor Kinome_245, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001637
Genes associated with Kinase Inhibitor MRT67307 Genes associated with Kinase Inhibitor MRT67307, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
TAX019329
GO:0017002 molecular function activin activated receptor activity Combining with activin and transmitting the signal from one side of the membrane to the other to ini (more detail) 7 NA Homo sapiens
TAX019023
GO:0016433 molecular function rRNA (adenine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA contain (more detail) 7 NA Homo sapiens
TAX015311
GO:0004673 molecular function protein histidine kinase activity Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine. (more detail) 7 NA Homo sapiens
PEX000267
BIR: Inhibitor of Apoptosis domain BIR stands for Baculovirus Inhibitor of apoptosis protein Repeat. It is found repeated in inhibitor (more detail) 7 NA Homo sapiens
MOX011743
Genes associated with Computational Drug Signature CHEMBL74983 Genes associated with Computational Drug Signature CHEMBL74983, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
FEX002728
Sarcoma Baird05 12genes Table 2. Tyrosine kinases and receptor tyrosine kinases associated with individual tumor groups (sho (more detail) 7 16230383 Homo sapiens
MEX001660
Genes associated with Kinase Inhibitor GW827099X Genes associated with Kinase Inhibitor GW827099X, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002185
Genes associated with Kinase Inhibitor Kinome 507 Genes associated with Kinase Inhibitor Kinome_507, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX003088
Genes associated with Computational Drug Signature Ranirestat Genes associated with Computational Drug Signature Ranirestat, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
MOX006665
Genes associated with Computational Drug Signature AGN PC 001QKA Genes associated with Computational Drug Signature AGN-PC-001QKA, curated by the Drug Signature Data (more detail) 7 25990557 Homo sapiens
TAX014774
GO:0003720 molecular function telomerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes (more detail) 7 NA Homo sapiens
TAX015329
GO:0004703 molecular function G protein coupled receptor kinase activity Catalysis of the reaction: ATP + G-protein coupled receptor = ADP + G-protein coupled receptor phosp (more detail) 7 NA Homo sapiens
MOX014397
Genes associated with Computational Drug Signature PD173955 Genes associated with Computational Drug Signature PD173955, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens
MOX014577
Genes associated with Computational Drug Signature PONATINIB Genes associated with Computational Drug Signature PONATINIB, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens
MEX001379
Genes associated with Kinase Inhibitor Kinome 683 Genes associated with Kinase Inhibitor Kinome_683, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX001399
Genes associated with Kinase Inhibitor MLS002232309 Genes associated with Kinase Inhibitor MLS002232309, curated by the Drug Signature Database (DSigDB) (more detail) 7 25990557 Homo sapiens
MEX002270
Genes associated with Kinase Inhibitor Tozasertib Genes associated with Kinase Inhibitor Tozasertib, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX002330
Genes associated with Kinase Inhibitor Kinome 423 Genes associated with Kinase Inhibitor Kinome_423, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
IEI015099
Protein protein interactors of human gene XAF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene XAF1 (SwissProt ID=Q (more detail) 12 17535438 Homo sapiens
TAX015866
GO:0005675 cellular component holo TFIIH complex A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the lar (more detail) 12 NA Homo sapiens
TAX017151
GO:0008250 cellular component oligosaccharyltransferase complex A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers li (more detail) 12 NA Homo sapiens
TAX016771
GO:0007077 biological process mitotic nuclear envelope disassembly The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell (more detail) 12 NA Homo sapiens
TAX034131
GO:1990001 biological process inhibition of cysteine type endopeptidase activity involved in apoptotic process Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an a (more detail) 10 NA Homo sapiens
TAX030815
GO:0097354 biological process prenylation The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups (more detail) 10 NA Homo sapiens
TAX019522
GO:0018342 biological process protein prenylation The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups (more detail) 10 NA Homo sapiens
TAX016463
GO:0006600 biological process creatine metabolic process The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a com (more detail) 10 NA Homo sapiens
PEX001635
zf B box: B box zinc finger (more detail) 10 NA Homo sapiens
TAX001339
Genes annotated by the GO term GO:0004712. Catalysis of the reaction: ATP + a protein serine/threonine/tyrosine = ADP + protein serine/threonine/tyrosine phosphate. (more detail) 10 NA Homo sapiens
MOX003319
Genes associated with Computational Drug Signature UNII W39547M0FP Genes associated with Computational Drug Signature UNII-W39547M0FP, curated by the Drug Signature Da (more detail) 10 25990557 Homo sapiens
WIG000670
Genes involved in Activation of the AP 1 family of transcription factors (more detail) 10 NA Homo sapiens
MAX002889
Protein kinase genes most significantly up regulated in ASPS (alveolar soft part sarcoma) tumors compared to four other types of primitive sarcomas. Specific chromosomal translocations encoding chimeric transcription factors are considered to play c (more detail) 10 NA Homo sapiens
MOX017941
Genes associated with Computational Drug Signature Afatinib Genes associated with Computational Drug Signature Afatinib, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
IEI007712
Protein protein interactors of human gene MARCHF3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MARCHF3 (SwissProt I (more detail) 8 17535438 Homo sapiens
IEI002453
Protein protein interactors of human gene CHAT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CHAT (SwissProt ID=P (more detail) 8 17535438 Homo sapiens
TAX033277
GO:1904047 molecular function S adenosyl L methionine binding Interacting selectively and non-covalently with S-adenosyl-L-methionine. (more detail) 8 NA Homo sapiens
TAX023290
GO:0036155 biological process acylglycerol acyl chain remodeling Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation react (more detail) 8 NA Homo sapiens
TAX025980
GO:0047760 molecular function butyrate CoA ligase activity Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA. (more detail) 8 NA Homo sapiens
IEI012242
Protein protein interactors of human gene SIT1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SIT1 (SwissProt ID=Q (more detail) 8 17535438 Homo sapiens
IEI005586
Protein protein interactors of human gene GTF2H5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GTF2H5 (SwissProt ID (more detail) 8 17535438 Homo sapiens
MOX017541
Genes associated with Computational Drug Signature PONATINIB Genes associated with Computational Drug Signature PONATINIB, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
TAX016709
GO:0006975 biological process DNA damage induced protein phosphorylation The widespread phosphorylation of various molecules, triggering many downstream processes, that occu (more detail) 8 NA Homo sapiens
TAX014903
GO:0003996 molecular function acyl CoA ligase activity Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-Co (more detail) 8 NA Homo sapiens
WIG002031
Methylation Pathways Methylation Pathways (more detail) 8 NA Homo sapiens
MAX000765
Genes required for both proliferation and CTNNB1 [GeneID=1499] activity in DLD 1 cell (colon cancer with APC [GeneID=324] deletions). Aberrant activation of the canonical WNT/beta-catenin pathway occurs in almost all colorectal cancer (more detail) 8 NA Homo sapiens
TAX013447
GO:0000506 cellular component glycosylphosphatidylinositol N acetylglucosaminyltransferase (GPI GnT) complex An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidyli (more detail) 8 NA Homo sapiens
MOX014671
Genes associated with Computational Drug Signature Purvalanol B Genes associated with Computational Drug Signature Purvalanol B, curated by the Drug Signature Datab (more detail) 8 25990557 Homo sapiens
WAG000110
Phosphorylase kinase activates glycogen phosphorylase (more detail) 8 NA Homo sapiens
PEX002045
GST C: Glutathione S transferase, C terminal domain GST conjugates reduced glutathione to a variety of targets including S-crystallin from squid, the eu (more detail) 8 NA Homo sapiens
MOX007562
Genes associated with Computational Drug Signature CEP 5104 Genes associated with Computational Drug Signature CEP-5104, curated by the Drug Signature Database (more detail) 6 25990557 Homo sapiens
MEX001299
Genes associated with Kinase Inhibitor Kinome 2199 Genes associated with Kinase Inhibitor Kinome_2199, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001302
Genes associated with Kinase Inhibitor Kinome 569 Genes associated with Kinase Inhibitor Kinome_569, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001959
Genes associated with Kinase Inhibitor MLN 120B Genes associated with Kinase Inhibitor MLN-120B, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002056
Genes associated with Kinase Inhibitor Kinome 477 Genes associated with Kinase Inhibitor Kinome_477, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002088
Genes associated with Kinase Inhibitor CHEMBL403402 Genes associated with Kinase Inhibitor CHEMBL403402, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX002162
Genes associated with Kinase Inhibitor CHEMBL260092 Genes associated with Kinase Inhibitor CHEMBL260092, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX001521
Genes associated with Kinase Inhibitor Kinome 1109 Genes associated with Kinase Inhibitor Kinome_1109, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
TAX017900
GO:0010340 molecular function carboxyl O methyltransferase activity Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a (more detail) 6 NA Homo sapiens
TAX014805
GO:0003836 molecular function beta galactoside (CMP) alpha 2,3 sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galac (more detail) 6 NA Homo sapiens
TAX014812
GO:0003846 molecular function 2 acylglycerol O acyltransferase activity Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol. (more detail) 6 NA Homo sapiens
MEX001400
Genes associated with Kinase Inhibitor Kinome 461 Genes associated with Kinase Inhibitor Kinome_461, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002244
Genes associated with Kinase Inhibitor GW830365A Genes associated with Kinase Inhibitor GW830365A, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002266
Genes associated with Kinase Inhibitor CHEMBL272938 Genes associated with Kinase Inhibitor CHEMBL272938, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX002302
Genes associated with Kinase Inhibitor Kinome 108 Genes associated with Kinase Inhibitor Kinome_108, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001990
Genes associated with Kinase Inhibitor GSK269962A Genes associated with Kinase Inhibitor GSK269962A, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002349
Genes associated with Kinase Inhibitor CHEMBL373798 Genes associated with Kinase Inhibitor CHEMBL373798, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX002059
Genes associated with Kinase Inhibitor isogranulatimide Genes associated with Kinase Inhibitor isogranulatimide, curated by the Drug Signature Database (DSi (more detail) 6 25990557 Homo sapiens
MEX001458
Genes associated with Kinase Inhibitor Kinome 1067 Genes associated with Kinase Inhibitor Kinome_1067, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001511
Genes associated with Kinase Inhibitor Kinome 584 Genes associated with Kinase Inhibitor Kinome_584, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002190
Genes associated with Kinase Inhibitor Kinome 464 Genes associated with Kinase Inhibitor Kinome_464, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MOX013789
Genes associated with Computational Drug Signature Motesanib Genes associated with Computational Drug Signature Motesanib, curated by the Drug Signature Database (more detail) 6 25990557 Homo sapiens
TAX014896
GO:0003988 molecular function acetyl CoA C acyltransferase activity Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA. (more detail) 6 NA Homo sapiens
MEX001242
Genes associated with Kinase Inhibitor Entrectinib Genes associated with Kinase Inhibitor Entrectinib, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001997
Genes associated with Kinase Inhibitor Chelerythrine chloride Genes associated with Kinase Inhibitor Chelerythrine chloride, curated by the Drug Signature Databas (more detail) 6 25990557 Homo sapiens
MEX002362
Genes associated with Kinase Inhibitor BI 2536 Genes associated with Kinase Inhibitor BI 2536, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001784
Genes associated with Kinase Inhibitor TPCA 1 Genes associated with Kinase Inhibitor TPCA-1, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001827
Genes associated with Kinase Inhibitor WHI P154 Genes associated with Kinase Inhibitor WHI-P154, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002194
Genes associated with Kinase Inhibitor Kinome 460 Genes associated with Kinase Inhibitor Kinome_460, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
TAX014799
GO:0003828 molecular function alpha N acetylneuraminate alpha 2,8 sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactos (more detail) 6 NA Homo sapiens
PEX001609
Recep L domain: Receptor L domain The L domains from these receptors make up the bilobal ligand binding site. Each L domain consists o (more detail) 6 NA Homo sapiens
MOX012705
Genes associated with Computational Drug Signature Flt 3 Inhibitor II Genes associated with Computational Drug Signature Flt-3 Inhibitor II, curated by the Drug Signature (more detail) 6 25990557 Homo sapiens
MEX001306
Genes associated with Kinase Inhibitor Kinome 1286 Genes associated with Kinase Inhibitor Kinome_1286, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002219
Genes associated with Kinase Inhibitor HYPOTHEMYCIN Genes associated with Kinase Inhibitor HYPOTHEMYCIN, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX001908
Genes associated with Kinase Inhibitor CHEMBL213505 Genes associated with Kinase Inhibitor CHEMBL213505, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX001583
Genes associated with Kinase Inhibitor Kinome 424 Genes associated with Kinase Inhibitor Kinome_424, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001994
Genes associated with Kinase Inhibitor Kinome 1896 Genes associated with Kinase Inhibitor Kinome_1896, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002085
Genes associated with Kinase Inhibitor RNA Dependent Protein Kinase Inhibitor, Negative Control Genes associated with Kinase Inhibitor RNA-Dependent Protein Kinase Inhibitor, Negative Control, cur (more detail) 6 25990557 Homo sapiens
MEX001459
Genes associated with Kinase Inhibitor GW784752X Genes associated with Kinase Inhibitor GW784752X, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001526
Genes associated with Kinase Inhibitor Kinome 2680 Genes associated with Kinase Inhibitor Kinome_2680, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
TAX019025
GO:0016435 molecular function rRNA (guanine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA contain (more detail) 6 NA Homo sapiens
TAX013758
GO:0001665 molecular function alpha N acetylgalactosaminide alpha 2,6 sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl (more detail) 6 NA Homo sapiens
PEX002503
Kelch 1: Kelch motif The kelch motif was initially discovered in Kelch (Swiss:Q04652). In this protein there are six copi (more detail) 6 NA Homo sapiens
PEX000885
Cyclin C: Cyclin, C terminal domain Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a Uracil-DNA glycosylase that is r (more detail) 6 NA Homo sapiens
WAG000686
DNA replication initiation (more detail) 6 NA Homo sapiens
WAG000269
EphrinB EPHB pathway (more detail) 6 NA Homo sapiens
MEX001254
Genes associated with Kinase Inhibitor GW830263A Genes associated with Kinase Inhibitor GW830263A, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002018
Genes associated with Kinase Inhibitor Wee1 Inhibitor Genes associated with Kinase Inhibitor Wee1 Inhibitor, curated by the Drug Signature Database (DSigD (more detail) 6 25990557 Homo sapiens
MEX002022
Genes associated with Kinase Inhibitor 877400 66 3 Genes associated with Kinase Inhibitor 877400-66-3, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002067
Genes associated with Kinase Inhibitor INDIRUBIN 3' MONOXIME Genes associated with Kinase Inhibitor INDIRUBIN-3'-MONOXIME, curated by the Drug Signature Database (more detail) 6 25990557 Homo sapiens
MEX001814
Genes associated with Kinase Inhibitor CHEMBL273187 Genes associated with Kinase Inhibitor CHEMBL273187, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX001865
Genes associated with Kinase Inhibitor CHEMBL1090360 Genes associated with Kinase Inhibitor CHEMBL1090360, curated by the Drug Signature Database (DSigDB (more detail) 6 25990557 Homo sapiens
MEX001173
Genes associated with Approved Drug ponatinib Genes associated with Approved Drug ponatinib, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
TAX015009
GO:0004144 molecular function diacylglycerol O acyltransferase activity Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol. (more detail) 6 NA Homo sapiens
TAX015129
GO:0004430 molecular function 1 phosphatidylinositol 4 kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-p (more detail) 6 NA Homo sapiens
TAX015152
GO:0004468 molecular function lysine N acetyltransferase activity, acting on acetyl phosphate as donor Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine. (more detail) 6 NA Homo sapiens
PEX001578
Furin like: Furin like cysteine rich region (more detail) 6 NA Homo sapiens
MOX014398
Genes associated with Computational Drug Signature PD180970 Genes associated with Computational Drug Signature PD180970, curated by the Drug Signature Database (more detail) 6 25990557 Homo sapiens
MEX001437
Genes associated with Kinase Inhibitor GW396574X Genes associated with Kinase Inhibitor GW396574X, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001230
Genes associated with Kinase Inhibitor amlexanox Genes associated with Kinase Inhibitor amlexanox, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002315
Genes associated with Kinase Inhibitor CHEMBL404366 Genes associated with Kinase Inhibitor CHEMBL404366, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX002210
Genes associated with Kinase Inhibitor LY 294002 Genes associated with Kinase Inhibitor LY 294002, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001593
Genes associated with Kinase Inhibitor Kinome 1056 Genes associated with Kinase Inhibitor Kinome_1056, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002256
Genes associated with Kinase Inhibitor NVP BEZ235 Genes associated with Kinase Inhibitor NVP-BEZ235, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001626
Genes associated with Kinase Inhibitor CHEMBL1096634 Genes associated with Kinase Inhibitor CHEMBL1096634, curated by the Drug Signature Database (DSigDB (more detail) 6 25990557 Homo sapiens
MEX002364
Genes associated with Kinase Inhibitor Kinome 476 Genes associated with Kinase Inhibitor Kinome_476, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001744
Genes associated with Kinase Inhibitor CHEMBL1964441 Genes associated with Kinase Inhibitor CHEMBL1964441, curated by the Drug Signature Database (DSigDB (more detail) 6 25990557 Homo sapiens
MEX001863
Genes associated with Kinase Inhibitor XMD8 92 Genes associated with Kinase Inhibitor XMD8-92, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MOX013717
Genes associated with Computational Drug Signature Midostaurin Genes associated with Computational Drug Signature Midostaurin, curated by the Drug Signature Databa (more detail) 6 25990557 Homo sapiens
PEX002377
PrmA: Ribosomal protein L11 methyltransferase (PrmA) This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences. (more detail) 6 NA Homo sapiens
MOX014436
Genes associated with Computational Drug Signature PF 573228 Genes associated with Computational Drug Signature PF 573228, curated by the Drug Signature Database (more detail) 6 25990557 Homo sapiens
WAG000528
Telomere C strand synthesis initiation (more detail) 6 NA Homo sapiens
MEX001257
Genes associated with Kinase Inhibitor CHEMBL402846 Genes associated with Kinase Inhibitor CHEMBL402846, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX002241
Genes associated with Kinase Inhibitor BI 78D3 Genes associated with Kinase Inhibitor BI-78D3, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002021
Genes associated with Kinase Inhibitor Flt 3 Inhibitor II Genes associated with Kinase Inhibitor Flt-3 Inhibitor II, curated by the Drug Signature Database (D (more detail) 6 25990557 Homo sapiens
MEX001757
Genes associated with Kinase Inhibitor Kinome 132 Genes associated with Kinase Inhibitor Kinome_132, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001780
Genes associated with Kinase Inhibitor Kinome 875 Genes associated with Kinase Inhibitor Kinome_875, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001802
Genes associated with Kinase Inhibitor Kinome 3522 Genes associated with Kinase Inhibitor Kinome_3522, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001807
Genes associated with Kinase Inhibitor Kinome 583 Genes associated with Kinase Inhibitor Kinome_583, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001487
Genes associated with Kinase Inhibitor GW683134A Genes associated with Kinase Inhibitor GW683134A, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001220
Genes associated with Kinase Inhibitor Go 6976 Genes associated with Kinase Inhibitor Go 6976, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
TAX016528
GO:0006686 biological process sphingomyelin biosynthetic process The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl (more detail) 6 NA Homo sapiens
TAX013282
GO:0000155 molecular function phosphorelay sensor kinase activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular (more detail) 6 NA Homo sapiens
MEX001231
Genes associated with Kinase Inhibitor CHEMBL1096626 Genes associated with Kinase Inhibitor CHEMBL1096626, curated by the Drug Signature Database (DSigDB (more detail) 6 25990557 Homo sapiens
MEX001281
Genes associated with Kinase Inhibitor Kinome 768 Genes associated with Kinase Inhibitor Kinome_768, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001359
Genes associated with Kinase Inhibitor CHEMBL374044 Genes associated with Kinase Inhibitor CHEMBL374044, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX001648
Genes associated with Kinase Inhibitor Kinome 2200 Genes associated with Kinase Inhibitor Kinome_2200, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002217
Genes associated with Kinase Inhibitor Kinome 838 Genes associated with Kinase Inhibitor Kinome_838, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001954
Genes associated with Kinase Inhibitor CHEMBL271441 Genes associated with Kinase Inhibitor CHEMBL271441, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MEX001986
Genes associated with Kinase Inhibitor PHA 767491 Genes associated with Kinase Inhibitor PHA-767491, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001672
Genes associated with Kinase Inhibitor Kinome 2672 Genes associated with Kinase Inhibitor Kinome_2672, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX002150
Genes associated with Kinase Inhibitor pp1 analog Genes associated with Kinase Inhibitor pp1 analog, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX001216
Genes associated with Kinase Inhibitor Oxindole Based Inhibitor 19 Genes associated with Kinase Inhibitor Oxindole-Based Inhibitor 19, curated by the Drug Signature Da (more detail) 6 25990557 Homo sapiens
TAX019426
GO:0017176 molecular function phosphatidylinositol N acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-gluc (more detail) 6 NA Homo sapiens
TAX025844
GO:0046975 molecular function histone methyltransferase activity (H3 K36 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl- (more detail) 6 NA Homo sapiens
IEI014872
Protein protein interactors of human gene VGF from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene VGF (SwissProt ID=O1 (more detail) 6 17535438 Homo sapiens
TAX026432
GO:0050291 molecular function sphingosine N acyltransferase activity Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine. (more detail) 6 NA Homo sapiens
TAX022521
GO:0034481 molecular function chondroitin sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bis (more detail) 6 NA Homo sapiens
TAX017534
GO:0009136 biological process purine nucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a c (more detail) 6 NA Homo sapiens
TAX028802
GO:0070212 biological process protein poly ADP ribosylation The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ri (more detail) 6 NA Homo sapiens
TAX019815
GO:0019788 molecular function NEDD8 transferase activity Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y --> Y-NE (more detail) 6 NA Homo sapiens
TAX025590
GO:0046476 biological process glycosylceramide biosynthetic process The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound fo (more detail) 6 NA Homo sapiens
TAX029119
GO:0070816 biological process phosphorylation of RNA polymerase II C terminal domain The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of (more detail) 6 NA Homo sapiens
TAX019435
GO:0017196 biological process N terminal peptidyl methionine acetylation The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionin (more detail) 6 NA Homo sapiens
TAX027311
GO:0051998 molecular function protein carboxyl O methyltransferase activity Catalysis of the transfer of a methyl group to a carboxyl group on a protein. (more detail) 6 NA Homo sapiens
TAX022915
GO:0035519 biological process protein K29 linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine (more detail) 6 NA Homo sapiens
TAX017574
GO:0009180 biological process purine ribonucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, (more detail) 6 NA Homo sapiens
TAX017582
GO:0009188 biological process ribonucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a co (more detail) 6 NA Homo sapiens
TAX019504
GO:0018242 biological process protein O linked glycosylation via serine The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the m (more detail) 6 NA Homo sapiens
TAX019209
GO:0016778 molecular function diphosphotransferase activity Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor). (more detail) 6 NA Homo sapiens
TAX020451
GO:0030311 biological process poly N acetyllactosamine biosynthetic process The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carboh (more detail) 6 NA Homo sapiens
IEI004747
Protein protein interactors of human gene FGF5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FGF5 (SwissProt ID=P (more detail) 6 17535438 Homo sapiens
TAX022752
GO:0035174 molecular function histone serine kinase activity Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of (more detail) 6 NA Homo sapiens
TAX027177
GO:0051766 molecular function inositol trisphosphate kinase activity Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP. (more detail) 6 NA Homo sapiens
TAX019000
GO:0016406 molecular function carnitine O acyltransferase activity Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule. (more detail) 6 NA Homo sapiens
IEI014238
Protein protein interactors of human gene TRIM34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM34 (SwissProt ID (more detail) 9 17535438 Homo sapiens
TAX031751
GO:0150065 biological process regulation of deacetylase activity Any process that modulates the frequency, rate or extent of deacetylase activity. (more detail) 9 NA Homo sapiens
IEI003981
Protein protein interactors of human gene EFNA4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EFNA4 (SwissProt ID= (more detail) 9 17535438 Homo sapiens
IEI013066
Protein protein interactors of human gene STAB2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STAB2 (SwissProt ID= (more detail) 9 17535438 Homo sapiens
TAX026490
GO:0050654 biological process chondroitin sulfate proteoglycan metabolic process The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein who (more detail) 9 NA Homo sapiens
TAX026486
GO:0050650 biological process chondroitin sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, (more detail) 9 NA Homo sapiens
TAX022427
GO:0034350 biological process regulation of glial cell apoptotic process Any process that modulates the frequency, rate, or extent of glial cell apoptotic process. (more detail) 9 NA Homo sapiens
MOX005434
Genes associated with Computational Drug Signature 1 NM PP1 Genes associated with Computational Drug Signature 1-NM-PP1, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens
WIG000856
Genes involved in G2/M DNA damage checkpoint (more detail) 9 NA Homo sapiens
MOX003409
Genes associated with Computational Drug Signature gw8510 Genes associated with Computational Drug Signature gw8510, curated by the Drug Signature Database (D (more detail) 7 25990557 Homo sapiens
TAX016869
GO:0007256 biological process activation of JNKK activity The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are i (more detail) 7 NA Homo sapiens
TAX013284
GO:0000160 biological process phosphorelay signal transduction system A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphoryl (more detail) 7 NA Homo sapiens
MOX012970
Genes associated with Computational Drug Signature gw8510 Genes associated with Computational Drug Signature gw8510, curated by the Drug Signature Database (D (more detail) 7 25990557 Homo sapiens
WAG000881
Cyclin A/B1 associated events during G2/M transition (more detail) 7 NA Homo sapiens
WIG002025
Arylamine metabolism Arylamine metabolism (more detail) 7 NA Homo sapiens
MAX001065
Genes from selected recurrently amplified regions in bone tissue tumors with supernumerary ring chromosomes. Ring chromosomes and/or giant marker chromosomes have been observed in a variety of human tumor type (more detail) 7 NA Homo sapiens
MOX015199
Genes associated with Computational Drug Signature Staurosporine, N Benzoyl Genes associated with Computational Drug Signature Staurosporine, N-Benzoyl, curated by the Drug Sig (more detail) 7 25990557 Homo sapiens
MOX002384
Genes associated with Computational Drug Signature 1 Pyrenemethanol Genes associated with Computational Drug Signature 1-Pyrenemethanol, curated by the Drug Signature D (more detail) 7 25990557 Homo sapiens
TAX016267
GO:0006348 biological process chromatin silencing at telomere Repression of transcription of telomeric DNA by altering the structure of chromatin. (more detail) 7 NA Homo sapiens
TAX030298
GO:0090045 biological process positive regulation of deacetylase activity Any process that activates or increases the frequency, rate or extent of deacetylase activity, the c (more detail) 7 NA Homo sapiens
TAX019503
GO:0018231 biological process peptidyl S diacylglycerol L cysteine biosynthetic process from peptidyl cysteine The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and p (more detail) 7 NA Homo sapiens
TAX021456
GO:0032324 biological process molybdopterin cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), (more detail) 7 NA Homo sapiens
IEI009782
Protein protein interactors of human gene PFKFB1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PFKFB1 (SwissProt ID (more detail) 7 17535438 Homo sapiens
TAX021014
GO:0031466 cellular component Cul5 RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form (more detail) 7 NA Homo sapiens
IEI011669
Protein protein interactors of human gene RSRP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RSRP1 (SwissProt ID= (more detail) 7 17535438 Homo sapiens
TAX034762
GO:2000544 biological process regulation of endothelial cell chemotaxis to fibroblast growth factor Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblas (more detail) 7 NA Homo sapiens
TAX024434
GO:0043545 biological process molybdopterin cofactor metabolic process The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the c (more detail) 7 NA Homo sapiens
TAX033648
GO:1904847 biological process regulation of cell chemotaxis to fibroblast growth factor Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth fac (more detail) 7 NA Homo sapiens
TAX026861
GO:0051189 biological process prosthetic group metabolic process The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of cert (more detail) 7 NA Homo sapiens
TAX019502
GO:0018230 biological process peptidyl L cysteine S palmitoylation The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form (more detail) 7 NA Homo sapiens
TAX023240
GO:0036066 biological process protein O linked fucosylation The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor (more detail) 7 NA Homo sapiens
PEX000097
Methyltransf 16: Lysine methyltransferase Methyltrans_16 is a lysine methyltransferase. Characterised members of this family are protein methy (more detail) 5 NA Homo sapiens
MEX001448
Genes associated with Kinase Inhibitor GSK571989A Genes associated with Kinase Inhibitor GSK571989A, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001263
Genes associated with Kinase Inhibitor Kinome 2305 Genes associated with Kinase Inhibitor Kinome_2305, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001360
Genes associated with Kinase Inhibitor Kinome 2119 Genes associated with Kinase Inhibitor Kinome_2119, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX002125
Genes associated with Kinase Inhibitor Kinome 126 Genes associated with Kinase Inhibitor Kinome_126, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MOX007563
Genes associated with Computational Drug Signature CEP 6331 Genes associated with Computational Drug Signature CEP-6331, curated by the Drug Signature Database (more detail) 5 25990557 Homo sapiens
TAX014984
GO:0004111 molecular function creatine kinase activity Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). (more detail) 5 NA Homo sapiens
TAX018437
GO:0015015 biological process heparan sulfate proteoglycan biosynthetic process, enzymatic modification The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerizati (more detail) 5 NA Homo sapiens
TAX017461
GO:0009008 molecular function DNA methyltransferase activity Catalysis of the transfer of a methyl group to a DNA molecule. (more detail) 5 NA Homo sapiens
TAX015069
GO:0004340 molecular function glucokinase activity Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate. (more detail) 5 NA Homo sapiens
TAX015548
GO:0005007 molecular function fibroblast growth factor activated receptor activity Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to (more detail) 5 NA Homo sapiens
PEX000219
MTS: Methyltransferase small domain This domain is found in ribosomal RNA small subunit methyltransferase C (eg Swiss:P44453) as well as (more detail) 5 NA Homo sapiens
TAX013423
GO:0000451 biological process rRNA 2' O methylation The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule dur (more detail) 5 NA Homo sapiens
MEX001413
Genes associated with Kinase Inhibitor GW621970X Genes associated with Kinase Inhibitor GW621970X, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001929
Genes associated with Kinase Inhibitor GW654652C Genes associated with Kinase Inhibitor GW654652C, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001947
Genes associated with Kinase Inhibitor GW771127A Genes associated with Kinase Inhibitor GW771127A, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001681
Genes associated with Kinase Inhibitor N (2 (Diethylamino)ethyl) 5 ((5 fluoro 2 oxoindolin 3 ylidene)methyl) 2,4 dimethyl 1H pyrrole 3 carboxamide Genes associated with Kinase Inhibitor N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene (more detail) 5 25990557 Homo sapiens
MEX001732
Genes associated with Kinase Inhibitor 3erk Genes associated with Kinase Inhibitor 3erk, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001752
Genes associated with Kinase Inhibitor Kinome 1123 Genes associated with Kinase Inhibitor Kinome_1123, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001776
Genes associated with Kinase Inhibitor JNK Inhibitor V Genes associated with Kinase Inhibitor JNK Inhibitor V, curated by the Drug Signature Database (DSig (more detail) 5 25990557 Homo sapiens
MEX002184
Genes associated with Kinase Inhibitor CHEMBL394619 Genes associated with Kinase Inhibitor CHEMBL394619, curated by the Drug Signature Database (DSigDB) (more detail) 5 25990557 Homo sapiens
MOX003031
Genes associated with Computational Drug Signature 2 Propen 1 one, 1 (2,5 dihydroxyphenyl) 3 phenyl Genes associated with Computational Drug Signature 2-Propen-1-one, 1-(2,5-dihydroxyphenyl)-3-phenyl- (more detail) 5 25990557 Homo sapiens
MOX005931
Genes associated with Computational Drug Signature 303727 31 3 Genes associated with Computational Drug Signature 303727-31-3, curated by the Drug Signature Databa (more detail) 5 25990557 Homo sapiens
TAX018436
GO:0015014 biological process heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process The chemical reactions and pathways resulting in the formation of polysaccharide chain component of (more detail) 5 NA Homo sapiens
TAX013526
GO:0000829 molecular function inositol heptakisphosphate kinase activity Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)- (more detail) 5 NA Homo sapiens
TAX013794
GO:0001727 molecular function lipid kinase activity Catalysis of the phosphorylation of a simple or complex lipid. (more detail) 5 NA Homo sapiens
TAX016038
GO:0005964 cellular component phosphorylase kinase complex An enzyme complex that catalyzes the phosphorylation of phosphorylase b to form phosphorylase a. (more detail) 5 NA Homo sapiens
TAX014866
GO:0003945 molecular function N acetyllactosamine synthase activity Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine. (more detail) 5 NA Homo sapiens
PEX000997
Methyltransf 12: Methyltransferase domain Members of this family are SAM dependent methyltransferases. (more detail) 5 NA Homo sapiens
MOX012427
Genes associated with Computational Drug Signature Dovitinib Genes associated with Computational Drug Signature Dovitinib, curated by the Drug Signature Database (more detail) 5 25990557 Homo sapiens
MOX015016
Genes associated with Computational Drug Signature SB 747651A Genes associated with Computational Drug Signature SB-747651A, curated by the Drug Signature Databas (more detail) 5 25990557 Homo sapiens
MEX001315
Genes associated with Kinase Inhibitor Kinome 1318 Genes associated with Kinase Inhibitor Kinome_1318, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001656
Genes associated with Kinase Inhibitor Kinome 601 Genes associated with Kinase Inhibitor Kinome_601, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX002227
Genes associated with Kinase Inhibitor CHEMBL404367 Genes associated with Kinase Inhibitor CHEMBL404367, curated by the Drug Signature Database (DSigDB) (more detail) 5 25990557 Homo sapiens
MEX001640
Genes associated with Kinase Inhibitor GDC 0941 Genes associated with Kinase Inhibitor GDC-0941, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001969
Genes associated with Kinase Inhibitor SB 216763 Genes associated with Kinase Inhibitor SB 216763, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MOX002021
Genes associated with Computational Drug Signature 88352 44 7 Genes associated with Computational Drug Signature 88352-44-7, curated by the Drug Signature Databas (more detail) 5 25990557 Homo sapiens
MOX001418
Genes associated with Computational Drug Signature Anthrarobin Genes associated with Computational Drug Signature Anthrarobin, curated by the Drug Signature Databa (more detail) 5 25990557 Homo sapiens
MEX002383
Genes associated with Kinase Inhibitor Kinome 825 Genes associated with Kinase Inhibitor Kinome_825, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX002043
Genes associated with Kinase Inhibitor Src Kinase Inhibitor I Genes associated with Kinase Inhibitor Src Kinase Inhibitor I, curated by the Drug Signature Databas (more detail) 5 25990557 Homo sapiens
MEX002070
Genes associated with Kinase Inhibitor Kinome 568 Genes associated with Kinase Inhibitor Kinome_568, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001810
Genes associated with Kinase Inhibitor GSK614526A Genes associated with Kinase Inhibitor GSK614526A, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001853
Genes associated with Kinase Inhibitor IRAK 1/4 Inhibitor Genes associated with Kinase Inhibitor IRAK-1/4 Inhibitor, curated by the Drug Signature Database (D (more detail) 5 25990557 Homo sapiens
MEX002188
Genes associated with Kinase Inhibitor GSK2334470 Genes associated with Kinase Inhibitor GSK2334470, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MOX000761
Genes associated with Computational Drug Signature Pinocembrin Genes associated with Computational Drug Signature Pinocembrin, curated by the Drug Signature Databa (more detail) 5 25990557 Homo sapiens
MOX002615
Genes associated with Computational Drug Signature 2,3,5 (Trigsyl)HQ Genes associated with Computational Drug Signature 2,3,5-(Trigsyl)HQ, curated by the Drug Signature (more detail) 5 25990557 Homo sapiens
TAX015370
GO:0004758 molecular function serine C palmitoyltransferase activity Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA. (more detail) 5 NA Homo sapiens
TAX016524
GO:0006682 biological process galactosylceramide biosynthetic process The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound (more detail) 5 NA Homo sapiens
TAX017861
GO:0010138 biological process pyrimidine ribonucleotide salvage The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide break (more detail) 5 NA Homo sapiens
TAX017435
GO:0008865 molecular function fructokinase activity Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate. (more detail) 5 NA Homo sapiens
TAX013524
GO:0000827 molecular function inositol 1,3,4,5,6 pentakisphosphate kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-my (more detail) 5 NA Homo sapiens
TAX013528
GO:0000832 molecular function inositol hexakisphosphate 5 kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D (more detail) 5 NA Homo sapiens
TAX015435
GO:0004849 molecular function uridine kinase activity Catalysis of the reaction: ATP + uridine = ADP + UMP. (more detail) 5 NA Homo sapiens
TAX016168
GO:0006172 biological process ADP biosynthetic process The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate. (more detail) 5 NA Homo sapiens
PEX000480
Methyltransf 31: Methyltransferase domain This family appears to have methyltransferase activity. (more detail) 5 NA Homo sapiens
PEX000875
BTK: BTK motif Zinc-binding motif containing conserved cysteines and a histidine. Always found C-terminal to PH dom (more detail) 5 NA Homo sapiens
MOX014396
Genes associated with Computational Drug Signature PD173952 Genes associated with Computational Drug Signature PD173952, curated by the Drug Signature Database (more detail) 5 25990557 Homo sapiens
MOX014451
Genes associated with Computational Drug Signature PHA 767491 Genes associated with Computational Drug Signature PHA-767491, curated by the Drug Signature Databas (more detail) 5 25990557 Homo sapiens
MOX014384
Genes associated with Computational Drug Signature PD 0173958 Genes associated with Computational Drug Signature PD-0173958, curated by the Drug Signature Databas (more detail) 5 25990557 Homo sapiens
POX000481
PathwayGeneSet, Reactome Genes associated with PathwayGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 5 NA Homo sapiens
MEX002027
Genes associated with Kinase Inhibitor Cediranib Genes associated with Kinase Inhibitor Cediranib, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX002148
Genes associated with Kinase Inhibitor Kinome 1143 Genes associated with Kinase Inhibitor Kinome_1143, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001498
Genes associated with Kinase Inhibitor Lapatinib Genes associated with Kinase Inhibitor Lapatinib, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001506
Genes associated with Kinase Inhibitor Kinome 28 Genes associated with Kinase Inhibitor Kinome_28, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001529
Genes associated with Kinase Inhibitor GW833373X Genes associated with Kinase Inhibitor GW833373X, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX002189
Genes associated with Kinase Inhibitor GDC 0879 Genes associated with Kinase Inhibitor GDC-0879, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
TAX015024
GO:0004169 molecular function dolichyl phosphate mannose protein mannosyltransferase activity Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosy (more detail) 5 NA Homo sapiens
TAX019034
GO:0016454 molecular function C palmitoyltransferase activity Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule. (more detail) 5 NA Homo sapiens
TAX013684
GO:0001537 molecular function N acetylgalactosamine 4 O sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenos (more detail) 5 NA Homo sapiens
TAX014875
GO:0003956 molecular function NAD(P)+ protein arginine ADP ribosyltransferase activity Catalysis of the reaction: NAD(P)+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine. (more detail) 5 NA Homo sapiens
PEX002319
GST C 2: Glutathione S transferase, C terminal domain This domain is closely related to Pfam:PF00043. (more detail) 5 NA Homo sapiens
WAG001097
Cytosolic sulfonation of small molecules (more detail) 5 NA Homo sapiens
MEX001631
Genes associated with Kinase Inhibitor Kinome 1106 Genes associated with Kinase Inhibitor Kinome_1106, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001677
Genes associated with Kinase Inhibitor GSK554170A Genes associated with Kinase Inhibitor GSK554170A, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001722
Genes associated with Kinase Inhibitor AST 487 Genes associated with Kinase Inhibitor AST 487, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX002051
Genes associated with Kinase Inhibitor 5 [5,6 Bis(Methyloxy) 1h Benzimidazol 1 Yl] 3 {[1 (2 Chlorophenyl)ethyl]oxy} 2 Thiophenecarboxamide Genes associated with Kinase Inhibitor 5-[5,6-Bis(Methyloxy)-1h-Benzimidazol-1-Yl]-3-{[1-(2-Chloroph (more detail) 5 25990557 Homo sapiens
PEX000357
F box like: F box like This is an F-box-like family. (more detail) 5 NA Homo sapiens
MOX015958
Genes associated with Computational Drug Signature ZK CDK Genes associated with Computational Drug Signature ZK CDK, curated by the Drug Signature Database (D (more detail) 5 25990557 Homo sapiens
TAX013267
GO:0000125 cellular component PCAF complex A large multiprotein complex that possesses histone acetyltransferase activity and is involved in re (more detail) 5 NA Homo sapiens
WAG001137
Synthesis of phosphatidic acid from lysophosphatidic acid (more detail) 5 NA Homo sapiens
MEX001275
Genes associated with Kinase Inhibitor 405169 16 6 Genes associated with Kinase Inhibitor 405169-16-6, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001368
Genes associated with Kinase Inhibitor GW876790X Genes associated with Kinase Inhibitor GW876790X, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001542
Genes associated with Kinase Inhibitor Kinome 3161 Genes associated with Kinase Inhibitor Kinome_3161, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001733
Genes associated with Kinase Inhibitor genistein Genes associated with Kinase Inhibitor genistein, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001759
Genes associated with Kinase Inhibitor Kinome 2098 Genes associated with Kinase Inhibitor Kinome_2098, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001822
Genes associated with Kinase Inhibitor Kinome 1140 Genes associated with Kinase Inhibitor Kinome_1140, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
TAX013525
GO:0000828 molecular function inositol hexakisphosphate kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-m (more detail) 5 NA Homo sapiens
TAX015113
GO:0004396 molecular function hexokinase activity Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate. (more detail) 5 NA Homo sapiens
TAX015303
GO:0004661 molecular function protein geranylgeranyltransferase activity Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether li (more detail) 5 NA Homo sapiens
TAX015320
GO:0004689 molecular function phosphorylase kinase activity Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a. (more detail) 5 NA Homo sapiens
PEX000333
ADK: Adenylate kinase (more detail) 5 NA Homo sapiens
PEX000338
Aminotran 1 2: Aminotransferase class I and II (more detail) 5 NA Homo sapiens
PEX002171
SIR2: Sir2 family This region is characteristic of Silent information regulator 2 (Sir2) proteins, or sirtuins. These (more detail) 5 NA Homo sapiens
POX000477
IsozymeGeneSet, KEGG Enzyme Genes associated with IsozymeGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 5 NA Homo sapiens
POX000476
PathwayGeneSet, Reactome Genes associated with PathwayGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 5 NA Homo sapiens
MOX014385
Genes associated with Computational Drug Signature PD 0179483 Genes associated with Computational Drug Signature PD-0179483, curated by the Drug Signature Databas (more detail) 5 25990557 Homo sapiens
MEX001587
Genes associated with Kinase Inhibitor Kinome 312 Genes associated with Kinase Inhibitor Kinome_312, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001714
Genes associated with Kinase Inhibitor GW770220A Genes associated with Kinase Inhibitor GW770220A, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001483
Genes associated with Kinase Inhibitor IKK 3 Inhibitor Genes associated with Kinase Inhibitor IKK-3 Inhibitor, curated by the Drug Signature Database (DSig (more detail) 5 25990557 Homo sapiens
MEX001868
Genes associated with Kinase Inhibitor Kinome 436 Genes associated with Kinase Inhibitor Kinome_436, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MOX010000
Genes associated with Computational Drug Signature CHEMBL383990 Genes associated with Computational Drug Signature CHEMBL383990, curated by the Drug Signature Datab (more detail) 5 25990557 Homo sapiens
MOX013152
Genes associated with Computational Drug Signature inositol 1,3,4,5 tetrakisphosphate Genes associated with Computational Drug Signature inositol 1,3,4,5-tetrakisphosphate, curated by th (more detail) 5 25990557 Homo sapiens
MOX013280
Genes associated with Computational Drug Signature Kinome 3019 Genes associated with Computational Drug Signature Kinome_3019, curated by the Drug Signature Databa (more detail) 5 25990557 Homo sapiens
TAX015364
GO:0004749 molecular function ribose phosphate diphosphokinase activity Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP (more detail) 5 NA Homo sapiens
TAX016232
GO:0006287 biological process base excision repair, gap filling Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few b (more detail) 5 NA Homo sapiens
POX000470
IsozymeGeneSet, KEGG Enzyme Genes associated with IsozymeGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 5 NA Homo sapiens
POX000478
PathwayGeneSet, Reactome Genes associated with PathwayGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 5 NA Homo sapiens
MEX001251
Genes associated with Kinase Inhibitor Canertinib Genes associated with Kinase Inhibitor Canertinib, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001298
Genes associated with Kinase Inhibitor Pazopanib Genes associated with Kinase Inhibitor Pazopanib, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001596
Genes associated with Kinase Inhibitor Linifanib Genes associated with Kinase Inhibitor Linifanib, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001665
Genes associated with Kinase Inhibitor Kinome 857 Genes associated with Kinase Inhibitor Kinome_857, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX002001
Genes associated with Kinase Inhibitor ZM 336372 Genes associated with Kinase Inhibitor ZM 336372, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001711
Genes associated with Kinase Inhibitor Kinome 1107 Genes associated with Kinase Inhibitor Kinome_1107, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MOX000275
Genes associated with Computational Drug Signature aloin Genes associated with Computational Drug Signature aloin, curated by the Drug Signature Database (DS (more detail) 5 25990557 Homo sapiens
MOX008674
Genes associated with Computational Drug Signature CHEMBL206866 Genes associated with Computational Drug Signature CHEMBL206866, curated by the Drug Signature Datab (more detail) 5 25990557 Homo sapiens
TAX016163
GO:0006166 biological process purine ribonucleoside salvage Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis. (more detail) 5 NA Homo sapiens
PEX001452
GST N 3: Glutathione S transferase, N terminal domain (more detail) 5 NA Homo sapiens
POX000472
IsozymeGeneSet, KEGG Enzyme Genes associated with IsozymeGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 5 NA Homo sapiens
MOX014197
Genes associated with Computational Drug Signature NU7026 Genes associated with Computational Drug Signature NU7026, curated by the Drug Signature Database (D (more detail) 5 25990557 Homo sapiens
POX000488
PathwayGeneSet, HumanCyc Genes associated with PathwayGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 5 NA Homo sapiens
TAX017376
GO:0008622 cellular component epsilon DNA polymerase complex A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of (more detail) 5 NA Homo sapiens
TAX031545
GO:0103068 molecular function leukotriene C4 gamma glutamyl transferase activity Catalysis of the reaction: leukotriene C4 + a standard alpha amino acid = leukotriene D4 + an (gamma (more detail) 5 NA Homo sapiens
TAX025456
GO:0046116 biological process queuosine metabolic process The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tR (more detail) 5 NA Homo sapiens
TAX031534
GO:0102953 molecular function hypoglycin A gamma glutamyl transpeptidase activity Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B (more detail) 5 NA Homo sapiens
TAX017269
GO:0008440 molecular function inositol 1,4,5 trisphosphate 3 kinase activity Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetra (more detail) 5 NA Homo sapiens
TAX019620
GO:0019158 molecular function mannokinase activity Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate. (more detail) 5 NA Homo sapiens
TAX020977
GO:0031415 cellular component NatA complex A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, o (more detail) 5 NA Homo sapiens
TAX027434
GO:0052723 molecular function inositol hexakisphosphate 1 kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inosito (more detail) 5 NA Homo sapiens
TAX027435
GO:0052724 molecular function inositol hexakisphosphate 3 kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inosito (more detail) 5 NA Homo sapiens
TAX021418
GO:0032262 biological process pyrimidine nucleotide salvage Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis (more detail) 5 NA Homo sapiens
TAX023312
GO:0036265 biological process RNA (guanine N7) methylation The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in (more detail) 5 NA Homo sapiens
TAX019010
GO:0016416 molecular function O palmitoyltransferase activity Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule. (more detail) 5 NA Homo sapiens
TAX024620
GO:0044206 biological process UMP salvage Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridin (more detail) 5 NA Homo sapiens
TAX025897
GO:0047238 molecular function glucuronosyl N acetylgalactosaminyl proteoglycan 4 beta N acetylgalactosaminyltransferase activity Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acety (more detail) 5 NA Homo sapiens
TAX026003
GO:0047961 molecular function glycine N acyltransferase activity Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine. (more detail) 5 NA Homo sapiens
TAX025805
GO:0046912 molecular function transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the (more detail) 5 NA Homo sapiens
TAX028532
GO:0061665 molecular function SUMO ligase activity Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S --> X + S-SUMO, (more detail) 5 NA Homo sapiens
TAX022124
GO:0033503 cellular component HULC complex A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin (more detail) 5 NA Homo sapiens
TAX018279
GO:0010994 biological process free ubiquitin chain polymerization The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin mon (more detail) 5 NA Homo sapiens
TAX025843
GO:0046974 molecular function histone methyltransferase activity (H3 K9 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L (more detail) 5 NA Homo sapiens
TAX031148
GO:0098821 molecular function BMP receptor activity Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal ac (more detail) 5 NA Homo sapiens
TAX024025
GO:0042799 molecular function histone methyltransferase activity (H4 K20 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl- (more detail) 5 NA Homo sapiens
TAX025845
GO:0046976 molecular function histone methyltransferase activity (H3 K27 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl- (more detail) 5 NA Homo sapiens
TAX027454
GO:0052811 molecular function 1 phosphatidylinositol 3 phosphate 4 kinase activity Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = a 1-phosphatidyl-1D- (more detail) 5 NA Homo sapiens
TAX017333
GO:0008532 molecular function N acetyllactosaminide beta 1,3 N acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminy (more detail) 5 NA Homo sapiens
TAX017374
GO:0008616 biological process queuosine biosynthetic process The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nuc (more detail) 5 NA Homo sapiens
TAX029008
GO:0070568 molecular function guanylyltransferase activity Catalysis of the transfer of a guanylyl group to an acceptor. (more detail) 5 NA Homo sapiens
TAX024682
GO:0044314 biological process protein K27 linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine (more detail) 5 NA Homo sapiens
TAX025886
GO:0047184 molecular function 1 acylglycerophosphocholine O acyltransferase activity Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA (more detail) 5 NA Homo sapiens
TAX022378
GO:0034227 biological process tRNA thio modification The addition a sulfur atom to a nucleotide in a tRNA molecule. (more detail) 5 NA Homo sapiens
TAX030955
GO:0097651 cellular component phosphatidylinositol 3 kinase complex, class I A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phos (more detail) 5 NA Homo sapiens
TAX019020
GO:0016428 molecular function tRNA (cytosine 5 ) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA contain (more detail) 5 NA Homo sapiens
IEI006836
Protein protein interactors of human gene KIF26A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KIF26A (SwissProt ID (more detail) 5 17535438 Homo sapiens
TAX019703
GO:0019375 biological process galactolipid biosynthetic process The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid cont (more detail) 5 NA Homo sapiens
TAX022428
GO:0034351 biological process negative regulation of glial cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic (more detail) 8 NA Homo sapiens
IEI009053
Protein protein interactors of human gene NRG1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene NRG1 (SwissProt ID=Q (more detail) 8 17535438 Homo sapiens
TAX021983
GO:0033129 biological process positive regulation of histone phosphorylation Any process that activates or increases the frequency, rate or extent of the addition of one or more (more detail) 8 NA Homo sapiens
IEI005132
Protein protein interactors of human gene GDF5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GDF5 (SwissProt ID=P (more detail) 8 17535438 Homo sapiens
TAX017555
GO:0009157 biological process deoxyribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphat (more detail) 8 NA Homo sapiens
IEI014652
Protein protein interactors of human gene UEVLD from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UEVLD (SwissProt ID= (more detail) 8 17535438 Homo sapiens
TAX020370
GO:0030202 biological process heparin metabolic process The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans f (more detail) 8 NA Homo sapiens
IEI008089
Protein protein interactors of human gene MOB3A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MOB3A (SwissProt ID= (more detail) 8 17535438 Homo sapiens
TAX020378
GO:0030210 biological process heparin biosynthetic process The chemical reactions and pathways resulting in the formation of heparin, any member of a group of (more detail) 8 NA Homo sapiens
IEI006924
Protein protein interactors of human gene KLHL21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KLHL21 (SwissProt ID (more detail) 8 17535438 Homo sapiens
IEI013148
Protein protein interactors of human gene STRADB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene STRADB (SwissProt ID (more detail) 8 17535438 Homo sapiens
TAX029093
GO:0070734 biological process histone H3 K27 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of (more detail) 8 NA Homo sapiens
MOX003011
Genes associated with Computational Drug Signature Tyrphostin AG 1296 Genes associated with Computational Drug Signature Tyrphostin AG 1296, curated by the Drug Signature (more detail) 8 25990557 Homo sapiens
WIG000201
Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. na (more detail) 8 NA Homo sapiens
MOX006911
Genes associated with Computational Drug Signature ALOISINE A Genes associated with Computational Drug Signature ALOISINE A, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
TAX013418
GO:0000439 cellular component core TFIIH complex The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or (more detail) 8 NA Homo sapiens
MOX003200
Genes associated with Computational Drug Signature Canertinib dihydrochloride Genes associated with Computational Drug Signature Canertinib dihydrochloride, curated by the Drug S (more detail) 8 25990557 Homo sapiens
MOX001992
Genes associated with Computational Drug Signature Hydroxychavicol Genes associated with Computational Drug Signature Hydroxychavicol, curated by the Drug Signature Da (more detail) 8 25990557 Homo sapiens
MOX012657
Genes associated with Computational Drug Signature Fasudil Genes associated with Computational Drug Signature Fasudil, curated by the Drug Signature Database ( (more detail) 8 25990557 Homo sapiens
TAX019524
GO:0018344 biological process protein geranylgeranylation The covalent attachment of a geranylgeranyl group to a protein. (more detail) 6 NA Homo sapiens
IEI014328
Protein protein interactors of human gene TRPS1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRPS1 (SwissProt ID= (more detail) 6 17535438 Homo sapiens
TAX025819
GO:0046935 molecular function 1 phosphatidylinositol 3 kinase regulator activity Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity. (more detail) 6 NA Homo sapiens
TAX030843
GO:0097413 cellular component Lewy body Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosp (more detail) 6 NA Homo sapiens
TAX023087
GO:0035791 biological process platelet derived growth factor receptor beta signaling pathway A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived g (more detail) 6 NA Homo sapiens
TAX026492
GO:0050656 molecular function 3' phosphoadenosine 5' phosphosulfate binding Interacting selectively and non-covalently with 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a natu (more detail) 6 NA Homo sapiens
TAX017580
GO:0009186 biological process deoxyribonucleoside diphosphate metabolic process The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisti (more detail) 6 NA Homo sapiens
TAX021287
GO:0032020 biological process ISG15 protein conjugation The covalent addition to a protein of ISG15, a ubiquitin-like protein. (more detail) 6 NA Homo sapiens
TAX024557
GO:0043985 biological process histone H4 R3 methylation The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histon (more detail) 6 NA Homo sapiens
IEI010761
Protein protein interactors of human gene PTPRR from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PTPRR (SwissProt ID= (more detail) 6 17535438 Homo sapiens
TAX027059
GO:0051552 biological process flavone metabolic process The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based o (more detail) 6 NA Homo sapiens
IEI014492
Protein protein interactors of human gene TULP4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TULP4 (SwissProt ID= (more detail) 6 17535438 Homo sapiens
IEI015628
Protein protein interactors of human gene ZNF57 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ZNF57 (SwissProt ID= (more detail) 6 17535438 Homo sapiens
TAX019784
GO:0019720 biological process Mo molybdopterin cofactor metabolic process The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catal (more detail) 6 NA Homo sapiens
IEI008108
Protein protein interactors of human gene MORC2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MORC2 (SwissProt ID= (more detail) 6 17535438 Homo sapiens
IEI009732
Protein protein interactors of human gene PDZRN3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PDZRN3 (SwissProt ID (more detail) 6 17535438 Homo sapiens
MOX014509
Genes associated with Computational Drug Signature phosphothreonine Genes associated with Computational Drug Signature phosphothreonine, curated by the Drug Signature D (more detail) 6 25990557 Homo sapiens
TAX015330
GO:0004704 molecular function NF kappaB inducing kinase activity Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase comp (more detail) 6 NA Homo sapiens
MOX004527
Genes associated with Computational Drug Signature phosphoadenosine phosphosulfate Genes associated with Computational Drug Signature phosphoadenosine phosphosulfate, curated by the D (more detail) 6 25990557 Homo sapiens
MAX003295
Selected genes down regulated in DU145 and PC 3 cells (prostate cancer) after treatment with the NSAID (non steroid anti inflammatory drug) sulindac [PubChem=5352] . Numerous studies show that nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in chemopreve (more detail) 6 NA Homo sapiens
MOX003412
Genes associated with Computational Drug Signature COX 2 Inhibitor I Genes associated with Computational Drug Signature COX-2 Inhibitor I, curated by the Drug Signature (more detail) 6 25990557 Homo sapiens
TAX017594
GO:0009202 biological process deoxyribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate (more detail) 6 NA Homo sapiens
WAG001313
Cyclin A:Cdk2 associated events at S phase entry (more detail) 6 NA Homo sapiens
MOX007373
Genes associated with Computational Drug Signature Brivanib Genes associated with Computational Drug Signature Brivanib, curated by the Drug Signature Database (more detail) 6 25990557 Homo sapiens
MOX002557
Genes associated with Computational Drug Signature Grepafloxacin Genes associated with Computational Drug Signature Grepafloxacin, curated by the Drug Signature Data (more detail) 6 25990557 Homo sapiens
TAX016587
GO:0006777 biological process Mo molybdopterin cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, ess (more detail) 6 NA Homo sapiens
WAG000283
Cyclin E associated events during G1/S transition (more detail) 6 NA Homo sapiens
WAG000008
cbl mediated ligand induced downregulation of egf receptors pathway As with many cell-surface receptors, activation of the EGF receptor can result in receptor interliza (more detail) 6 NA Homo sapiens
MOX014326
Genes associated with Computational Drug Signature p38 MAP Kinase Inhibitor III Genes associated with Computational Drug Signature p38 MAP Kinase Inhibitor III, curated by the Drug (more detail) 6 25990557 Homo sapiens
WAG000095
Glycogen breakdown (glycogenolysis) (more detail) 6 NA Homo sapiens
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