Y-U
(more detail)
439 NA Homo sapiens
TAX021263
GO:0031982 cellular component vesicle Any small, fluid-filled, spherical organelle enclosed by membrane. (more detail) 3043 NA Homo sapiens
TAX000322
Genes annotated by the GO term GO:0009057. The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates. (more detail) 133 NA Homo sapiens
TAX017796
GO:0009892 biological process negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions (more detail) 2683 NA Homo sapiens
TAX024467
GO:0043603 biological process cellular amide metabolic process The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an aci (more detail) 584 NA Homo sapiens
TAX000088
Genes annotated by the GO term GO:0044265. The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells. (more detail) 100 NA Homo sapiens
TAX018926
GO:0016236 biological process macroautophagy The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells (more detail) 88 NA Homo sapiens
TAX018850
GO:0016071 biological process mRNA metabolic process The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying (more detail) 641 NA Homo sapiens
TAX016555
GO:0006725 biological process cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized (more detail) 4620 NA Homo sapiens
TAX022473
GO:0034404 biological process nucleobase containing small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleobase-containing small mole (more detail) 148 NA Homo sapiens
TAX017478
GO:0009062 biological process fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic (more detail) 84 NA Homo sapiens
TAX016466
GO:0006605 biological process protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bou (more detail) 285 NA Homo sapiens
MOX004950
Genes associated with Computational Drug Signature cyclosporin A Genes associated with Computational Drug Signature cyclosporin A, curated by the Drug Signature Data (more detail) 4551 25990557 Homo sapiens
TAX021916
GO:0032991 cellular component protein containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipi (more detail) 4915 NA Homo sapiens
TAX016485
GO:0006631 biological process fatty acid metabolic process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated (more detail) 294 NA Homo sapiens
TAX024739
GO:0044421 cellular component extracellular region part Any constituent part of the extracellular region, the space external to the outermost structure of a (more detail) 3267 NA Homo sapiens
TAX030082
GO:0072594 biological process establishment of protein localization to organelle The directed movement of a protein to a specific location on or in an organelle. Encompasses establi (more detail) 356 NA Homo sapiens
TAX023422
GO:0036503 biological process ERAD pathway The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degrada (more detail) 77 NA Homo sapiens
TAX000051
Genes annotated by the GO term GO:0043285. The chemical reactions and pathways resulting in the breakdown of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. (more detail) 113 NA Homo sapiens
TAX025594
GO:0046483 biological process heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular (more detail) 4579 NA Homo sapiens
WAG000290
Eukaryotic Translation Termination (more detail) 83 NA Homo sapiens
IEI011614
Protein protein interactors of human gene RPS8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS8 (SwissProt ID=P (more detail) 221 17535438 Homo sapiens
WAG001152
Viral mRNA Translation (more detail) 81 NA Homo sapiens
TAX018964
GO:0016298 molecular function lipase activity Catalysis of the hydrolysis of a lipid or phospholipid. (more detail) 121 NA Homo sapiens
IEI011503
Protein protein interactors of human gene RPL11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL11 (SwissProt ID= (more detail) 222 17535438 Homo sapiens
TAX025552
GO:0046394 biological process carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid (more detail) 312 NA Homo sapiens
TAX018843
GO:0016053 biological process organic acid biosynthetic process The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound (more detail) 313 NA Homo sapiens
TAX028518
GO:0061630 molecular function ubiquitin protein ligase activity Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X (more detail) 231 NA Homo sapiens
TAX017474
GO:0009058 biological process biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-r (more detail) 4323 NA Homo sapiens
WIG000698
Genes involved in Antigen processing: Ubiquitination & Proteasome degradation (more detail) 199 NA Homo sapiens
TAX013278
GO:0000151 cellular component ubiquitin ligase complex A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase acti (more detail) 304 NA Homo sapiens
TAX028530
GO:0061659 molecular function ubiquitin like protein ligase activity Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction (more detail) 236 NA Homo sapiens
IEI011596
Protein protein interactors of human gene RPS3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS3 (SwissProt ID=P (more detail) 270 17535438 Homo sapiens
TAX024196
GO:0043169 molecular function cation binding Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net (more detail) 4200 NA Homo sapiens
WAG000504
Peptide chain elongation (more detail) 83 NA Homo sapiens
IEI011583
Protein protein interactors of human gene RPS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS2 (SwissProt ID=P (more detail) 236 17535438 Homo sapiens
TAX019105
GO:0016579 biological process protein deubiquitination The removal of one or more ubiquitin groups from a protein. (more detail) 269 NA Homo sapiens
IEI011598
Protein protein interactors of human gene RPS4X from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS4X (SwissProt ID= (more detail) 236 17535438 Homo sapiens
TAX029047
GO:0070646 biological process protein modification by small protein removal A protein modification process in which one or more covalently attached groups of a small protein, s (more detail) 285 NA Homo sapiens
WIG001988
Cytoplasmic Ribosomal Proteins Cytoplasmic Ribosomal Proteins (more detail) 89 NA Homo sapiens
TAX016473
GO:0006614 biological process SRP dependent cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation and is dependent upon two key (more detail) 89 NA Homo sapiens
TAX016081
GO:0006026 biological process aminoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containi (more detail) 68 NA Homo sapiens
WIG000763
Genes involved in Class I MHC mediated antigen processing & presentation (more detail) 237 NA Homo sapiens
WIG000612
Ribosome (more detail) 88 NA Homo sapiens
IEI011578
Protein protein interactors of human gene RPS16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS16 (SwissProt ID= (more detail) 217 17535438 Homo sapiens
TAX025777
GO:0046872 molecular function metal ion binding Interacting selectively and non-covalently with any metal ion. (more detail) 4109 NA Homo sapiens
TAX024909
GO:0045047 biological process protein targeting to ER The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained wit (more detail) 99 NA Homo sapiens
TAX032173
GO:1901576 biological process organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of an organic substance, any molecula (more detail) 4266 NA Homo sapiens
WAG000681
Formation of a pool of free 40S subunits (more detail) 92 NA Homo sapiens
IEI011508
Protein protein interactors of human gene RPL14 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL14 (SwissProt ID= (more detail) 193 17535438 Homo sapiens
TAX016472
GO:0006613 biological process cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation. The transport of most secret (more detail) 94 NA Homo sapiens
IEI011548
Protein protein interactors of human gene RPL7A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL7A (SwissProt ID= (more detail) 199 17535438 Homo sapiens
IEI011577
Protein protein interactors of human gene RPS15A from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS15A (SwissProt ID (more detail) 208 17535438 Homo sapiens
WIG001029
Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex (more detail) 166 NA Homo sapiens
TAX030084
GO:0072599 biological process establishment of protein localization to endoplasmic reticulum The directed movement of a protein to a specific location in the endoplasmic reticulum. (more detail) 103 NA Homo sapiens
IEI011509
Protein protein interactors of human gene RPL15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL15 (SwissProt ID= (more detail) 179 17535438 Homo sapiens
TAX032189
GO:1901616 biological process organic hydroxy compound catabolic process The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound. (more detail) 64 NA Homo sapiens
WAG000085
L13a mediated translational silencing of Ceruloplasmin expression (more detail) 102 NA Homo sapiens
IEI011587
Protein protein interactors of human gene RPS24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS24 (SwissProt ID= (more detail) 221 17535438 Homo sapiens
IEI011546
Protein protein interactors of human gene RPL6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL6 (SwissProt ID=Q (more detail) 217 17535438 Homo sapiens
IEI011511
Protein protein interactors of human gene RPL18 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL18 (SwissProt ID= (more detail) 193 17535438 Homo sapiens
IEI011517
Protein protein interactors of human gene RPL23 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL23 (SwissProt ID= (more detail) 206 17535438 Homo sapiens
IEI011504
Protein protein interactors of human gene RPL12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL12 (SwissProt ID= (more detail) 171 17535438 Homo sapiens
TAX020516
GO:0030433 biological process ubiquitin dependent ERAD pathway The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation (more detail) 63 NA Homo sapiens
IEI011586
Protein protein interactors of human gene RPS23 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS23 (SwissProt ID= (more detail) 188 17535438 Homo sapiens
WAG000273
Cap dependent Translation Initiation (more detail) 102 NA Homo sapiens
IEI011543
Protein protein interactors of human gene RPL4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL4 (SwissProt ID=P (more detail) 215 17535438 Homo sapiens
WAG000684
GTP hydrolysis and joining of the 60S ribosomal subunit (more detail) 103 NA Homo sapiens
IEI011513
Protein protein interactors of human gene RPL19 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL19 (SwissProt ID= (more detail) 169 17535438 Homo sapiens
IEI011584
Protein protein interactors of human gene RPS20 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS20 (SwissProt ID= (more detail) 181 17535438 Homo sapiens
TAX029220
GO:0070972 biological process protein localization to endoplasmic reticulum A process in which a protein is transported to, or maintained in, a location within the endoplasmic (more detail) 110 NA Homo sapiens
IEI011519
Protein protein interactors of human gene RPL24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL24 (SwissProt ID= (more detail) 186 17535438 Homo sapiens
TAX016082
GO:0006027 biological process glycosaminoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a g (more detail) 61 NA Homo sapiens
TAX022489
GO:0034440 biological process lipid oxidation The removal of one or more electrons from a lipid, with or without the concomitant removal of a prot (more detail) 77 NA Homo sapiens
TAX000573
Genes annotated by the GO term GO:0006508. The hydrolysis of a peptide bond or bonds within a protein. (more detail) 184 NA Homo sapiens
WIG000975
Genes involved in Metabolism of amino acids and derivatives (more detail) 192 NA Homo sapiens
IEI011585
Protein protein interactors of human gene RPS21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS21 (SwissProt ID= (more detail) 124 17535438 Homo sapiens
IEI011574
Protein protein interactors of human gene RPS13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS13 (SwissProt ID= (more detail) 198 17535438 Homo sapiens
TAX025541
GO:0046365 biological process monosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcoho (more detail) 60 NA Homo sapiens
IEI011514
Protein protein interactors of human gene RPL21 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL21 (SwissProt ID= (more detail) 171 17535438 Homo sapiens
TAX019709
GO:0019395 biological process fatty acid oxidation The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a (more detail) 76 NA Homo sapiens
TAX016471
GO:0006612 biological process protein targeting to membrane The process of directing proteins towards a membrane, usually using signals contained within the pro (more detail) 129 NA Homo sapiens
WIG001717
Ubiquitin Proteasome Dependent Proteolysis Ubiquitin-Proteasome Dependent Proteolysis (more detail) 77 NA Homo sapiens
IEI011550
Protein protein interactors of human gene RPL8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL8 (SwissProt ID=P (more detail) 174 17535438 Homo sapiens
TAX015272
GO:0004620 molecular function phospholipase activity Catalysis of the hydrolysis of a glycerophospholipid. (more detail) 97 NA Homo sapiens
TAX016487
GO:0006635 biological process fatty acid beta oxidation A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fa (more detail) 56 NA Homo sapiens
IEI011528
Protein protein interactors of human gene RPL31 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL31 (SwissProt ID= (more detail) 178 17535438 Homo sapiens
TAX024657
GO:0044273 biological process sulfur compound catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, suc (more detail) 55 NA Homo sapiens
IEI011588
Protein protein interactors of human gene RPS25 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS25 (SwissProt ID= (more detail) 150 17535438 Homo sapiens
WIG000638
Ubiquitin mediated proteolysis Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions (more detail) 130 NA Homo sapiens
TAX000542
Genes annotated by the GO term GO:0030163. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. (more detail) 65 NA Homo sapiens
TAX001400
Genes annotated by the GO term GO:0003735. The action of a molecule that contributes to the structural integrity of the ribosome. (more detail) 80 NA Homo sapiens
WAG000600
Ribosome (more detail) 66 NA Homo sapiens
WAG000988
Ubiquitin mediated proteolysis Protein ubiquitition plays an important role in eukaryotic cellular processes. It mainly functions a (more detail) 121 NA Homo sapiens
TAX027427
GO:0052689 molecular function carboxylic ester hydrolase activity Catalysis of the hydrolysis of a carboxylic ester bond. (more detail) 135 NA Homo sapiens
TAX000093
Genes annotated by the GO term GO:0044257. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. (more detail) 54 NA Homo sapiens
TAX023391
GO:0036459 molecular function thiol dependent ubiquitinyl hydrolase activity Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bon (more detail) 122 NA Homo sapiens
TAX026859
GO:0051187 biological process cofactor catabolic process The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is re (more detail) 51 NA Homo sapiens
TAX030034
GO:0072523 biological process purine containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. (more detail) 51 NA Homo sapiens
TAX031464
GO:0101005 molecular function ubiquitinyl hydrolase activity Catalysis of the hydrolysis of ubiquitin from proteins and other molecules. (more detail) 123 NA Homo sapiens
TAX016314
GO:0006413 biological process translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein. (more detail) 139 NA Homo sapiens
IEI011527
Protein protein interactors of human gene RPL30 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL30 (SwissProt ID= (more detail) 143 17535438 Homo sapiens
IEI011555
Protein protein interactors of human gene RPLP2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPLP2 (SwissProt ID= (more detail) 147 17535438 Homo sapiens
TAX019677
GO:0019320 biological process hexose catabolic process The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a (more detail) 50 NA Homo sapiens
TAX024221
GO:0043202 cellular component lysosomal lumen The volume enclosed within the lysosomal membrane. (more detail) 93 NA Homo sapiens
IEI011573
Protein protein interactors of human gene RPS12 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS12 (SwissProt ID= (more detail) 103 17535438 Homo sapiens
WIG001145
Genes involved in Regulation of mitotic cell cycle (more detail) 79 NA Homo sapiens
TAX019811
GO:0019783 molecular function ubiquitin like protein specific protease activity Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin o (more detail) 131 NA Homo sapiens
TAX022591
GO:0034656 biological process nucleobase containing small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small mole (more detail) 48 NA Homo sapiens
FOX000132
Neighborhood of EIF3S6 Neighborhood of EIF3S6 eukaryotic translation initiation factor 3, subunit 6 48kDa in the GNF2 expr (more detail) 116 NA Homo sapiens
IEI011502
Protein protein interactors of human gene RPL10L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPL10L (SwissProt ID (more detail) 100 17535438 Homo sapiens
FOX000417
Neighborhood of TPT1 Neighborhood of TPT1 tumor protein, translationally-controlled 1 in the MORF expression compendium (more detail) 100 NA Homo sapiens
TAX025479
GO:0046164 biological process alcohol catabolic process The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compou (more detail) 47 NA Homo sapiens
TAX025610
GO:0046503 biological process glycerolipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a gl (more detail) 45 NA Homo sapiens
TAX016181
GO:0006195 biological process purine nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound co (more detail) 44 NA Homo sapiens
TAX028559
GO:0061726 biological process mitochondrion disassembly The disaggregation of a mitochondrion into its constituent components. (more detail) 43 NA Homo sapiens
TAX013408
GO:0000422 biological process autophagy of mitochondrion The autophagic process in which mitochondria are delivered to the vacuole and degraded in response t (more detail) 43 NA Homo sapiens
FOX000084
Neighborhood of TPT1 Neighborhood of TPT1 tumor protein, translationally-controlled 1 in the GCM expression compendium (more detail) 65 NA Homo sapiens
WIG000702
Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins (more detail) 67 NA Homo sapiens
TAX032214
GO:1901658 biological process glycosyl compound catabolic process The chemical reactions and pathways resulting in the breakdown of glycosyl compound. (more detail) 41 NA Homo sapiens
WIG000703
Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (more detail) 66 NA Homo sapiens
TAX024050
GO:0042866 biological process pyruvate biosynthetic process The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate. (more detail) 42 NA Homo sapiens
TAX019328
GO:0017001 biological process antibiotic catabolic process The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced b (more detail) 39 NA Homo sapiens
TAX016126
GO:0006096 biological process glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with (more detail) 38 NA Homo sapiens
FEX001267
Leukemia Durig03 88genes Table 4. Ribosomal cluster identified by hierarchical cluster analysis (more detail) 78 12456497 Homo sapiens
WIG001146
Genes involved in Regulation of mRNA Stability by Proteins that Bind AU rich Elements (more detail) 82 NA Homo sapiens
TAX020569
GO:0030574 biological process collagen catabolic process The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extrac (more detail) 37 NA Homo sapiens
TAX013547
GO:0000932 cellular component P body A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Pr (more detail) 81 NA Homo sapiens
TAX016577
GO:0006757 biological process ATP generation from ADP The process of introducing a phosphate group into ADP, adenosine diphosphate, to produce ATP. (more detail) 39 NA Homo sapiens
TAX015433
GO:0004843 molecular function thiol dependent ubiquitin specific protease activity Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ub (more detail) 79 NA Homo sapiens
IEI011593
Protein protein interactors of human gene RPS27L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPS27L (SwissProt ID (more detail) 73 17535438 Homo sapiens
TAX024647
GO:0044257 biological process cellular protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. (more detail) 36 NA Homo sapiens
TAX020842
GO:0031145 biological process anaphase promoting complex dependent catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 36 NA Homo sapiens
WIG000614
RNA degradation The correct processing, quality control and turnover of cellular RNA molecules are critical to many (more detail) 56 NA Homo sapiens
WAG000672
Cdc20:Phospho APC/C mediated degradation of Cyclin A (more detail) 59 NA Homo sapiens
TAX025401
GO:0046031 biological process ADP metabolic process The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate. (more detail) 47 NA Homo sapiens
TAX013350
GO:0000291 biological process nuclear transcribed mRNA catabolic process, exonucleolytic The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-t (more detail) 35 NA Homo sapiens
TAX029196
GO:0070936 biological process protein K48 linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine (more detail) 48 NA Homo sapiens
IEI007045
Protein protein interactors of human gene KRT75 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KRT75 (SwissProt ID= (more detail) 81 17535438 Homo sapiens
TAX030040
GO:0072529 biological process pyrimidine containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, (more detail) 34 NA Homo sapiens
WAG000874
APC/C:Cdc20 mediated degradation of Securin (more detail) 57 NA Homo sapiens
WAG000599
Glycolysis / Gluconeogenesis Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (e (more detail) 79 NA Homo sapiens
TAX032748
GO:1903008 biological process organelle disassembly The disaggregation of an organelle into its constituent components. (more detail) 66 NA Homo sapiens
TAX017579
GO:0009185 biological process ribonucleoside diphosphate metabolic process The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of (more detail) 63 NA Homo sapiens
WIG000716
Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C (more detail) 58 NA Homo sapiens
TAX019572
GO:0019005 cellular component SCF ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form (more detail) 50 NA Homo sapiens
WAG001078
Autodegradation of Cdh1 by Cdh1:APC/C (more detail) 56 NA Homo sapiens
WAG000275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (more detail) 56 NA Homo sapiens
TAX024536
GO:0043928 biological process exonucleolytic nuclear transcribed mRNA catabolic process involved in deadenylation dependent decay The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-t (more detail) 33 NA Homo sapiens
TAX017561
GO:0009164 biological process nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any one of a family of organic mol (more detail) 33 NA Homo sapiens
TAX024173
GO:0043130 molecular function ubiquitin binding Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to o (more detail) 69 NA Homo sapiens
TAX020197
GO:0022625 cellular component cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol. (more detail) 66 NA Homo sapiens
TAX017573
GO:0009179 biological process purine ribonucleoside diphosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisti (more detail) 61 NA Homo sapiens
TAX017533
GO:0009135 biological process purine nucleoside diphosphate metabolic process The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting o (more detail) 61 NA Homo sapiens
TAX024198
GO:0043171 biological process peptide catabolic process The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more ( (more detail) 32 NA Homo sapiens
TAX017675
GO:0009395 biological process phospholipid catabolic process The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containin (more detail) 32 NA Homo sapiens
TAX017638
GO:0009261 biological process ribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consi (more detail) 32 NA Homo sapiens
TAX024454
GO:0043574 biological process peroxisomal transport Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle tha (more detail) 68 NA Homo sapiens
TAX000308
Genes annotated by the GO term GO:0016042. The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. (more detail) 38 NA Homo sapiens
FOX000226
Neighborhood of TPT1 Neighborhood of TPT1 tumor protein, translationally-controlled 1 in the GNF2 expression compendium (more detail) 38 NA Homo sapiens
WIG000788
Genes involved in Deadenylation dependent mRNA decay (more detail) 43 NA Homo sapiens
WIG000640
Valine, leucine and isoleucine degradation (more detail) 43 NA Homo sapiens
TAX014103
GO:0002181 biological process cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This i (more detail) 43 NA Homo sapiens
TAX019692
GO:0019363 biological process pyridine nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotid (more detail) 69 NA Homo sapiens
TAX019690
GO:0019359 biological process nicotinamide nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucl (more detail) 69 NA Homo sapiens
TAX025580
GO:0046464 biological process acylglycerol catabolic process The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or tr (more detail) 31 NA Homo sapiens
TAX025577
GO:0046461 biological process neutral lipid catabolic process The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only solubl (more detail) 31 NA Homo sapiens
TAX017552
GO:0009154 biological process purine ribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compoun (more detail) 31 NA Homo sapiens
TAX030100
GO:0072662 biological process protein localization to peroxisome A process in which a protein is transported to, or maintained at, a location in a peroxisome. (more detail) 67 NA Homo sapiens
TAX030101
GO:0072663 biological process establishment of protein localization to peroxisome The directed movement of a protein to a specific location in a peroxisome. (more detail) 67 NA Homo sapiens
TAX016481
GO:0006625 biological process protein targeting to peroxisome The process of directing proteins towards the peroxisome, usually using signals contained within the (more detail) 67 NA Homo sapiens
TAX033899
GO:1905369 cellular component endopeptidase complex A protein complex which is capable of endopeptidase activity. (more detail) 64 NA Homo sapiens
TAX000085
Genes annotated by the GO term GO:0044242. The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells. (more detail) 35 NA Homo sapiens
TAX013228
GO:0000045 biological process autophagosome assembly The formation of a double membrane-bounded structure, the autophagosome, that occurs when a speciali (more detail) 47 NA Homo sapiens
WAG000807
Valine, leucine and isoleucine degradation (more detail) 42 NA Homo sapiens
TAX033755
GO:1905037 biological process autophagosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of co (more detail) 50 NA Homo sapiens
TAX030551
GO:0090503 biological process RNA phosphodiester bond hydrolysis, exonucleolytic The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds (more detail) 38 NA Homo sapiens
TAX013446
GO:0000502 cellular component proteasome complex A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and s (more detail) 63 NA Homo sapiens
TAX015209
GO:0004532 molecular function exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA mole (more detail) 37 NA Homo sapiens
TAX017490
GO:0009074 biological process aromatic amino acid family catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino (more detail) 29 NA Homo sapiens
TAX016070
GO:0006007 biological process glucose catabolic process The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexo (more detail) 29 NA Homo sapiens
IEI003663
Protein protein interactors of human gene DNAJC10 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAJC10 (SwissProt I (more detail) 63 17535438 Homo sapiens
TAX021894
GO:0032963 biological process collagen metabolic process The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very h (more detail) 54 NA Homo sapiens
WAG000397
Fatty acid metabolism (more detail) 52 NA Homo sapiens
TAX024658
GO:0044275 biological process cellular carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of o (more detail) 28 NA Homo sapiens
TAX022594
GO:0034661 biological process ncRNA catabolic process The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs (more detail) 28 NA Homo sapiens
TAX023721
GO:0042219 biological process cellular modified amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids (more detail) 28 NA Homo sapiens
WIG001182
Genes involved in SCF beta TrCP mediated degradation of Emi1 (more detail) 50 NA Homo sapiens
TAX015931
GO:0005782 cellular component peroxisomal matrix The volume contained within the membranes of a peroxisome; in many cells the matrix contains a cryst (more detail) 51 NA Homo sapiens
WIG000793
Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) (more detail) 51 NA Homo sapiens
TAX021226
GO:0031907 cellular component microbody lumen The volume enclosed by the membranes of a microbody. (more detail) 51 NA Homo sapiens
TAX000426
Genes annotated by the GO term GO:0044270. The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds. (more detail) 29 NA Homo sapiens
MAX003161
Genes that comprise the proteasome gene module A major goal of cancer research is to match specific therapies to molecular targets in cancer. Genom (more detail) 49 NA Homo sapiens
TAX016162
GO:0006165 biological process nucleoside diphosphate phosphorylation The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside t (more detail) 56 NA Homo sapiens
TAX001230
Genes annotated by the GO term GO:0016298. Catalysis of the hydrolysis of a lipid or phospholipid. (more detail) 50 NA Homo sapiens
TAX025582
GO:0046466 biological process membrane lipid catabolic process The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found i (more detail) 26 NA Homo sapiens
TAX021792
GO:0032801 biological process receptor catabolic process The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecu (more detail) 26 NA Homo sapiens
TAX028509
GO:0061620 biological process glycolytic process through glucose 6 phosphate The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occu (more detail) 26 NA Homo sapiens
TAX017481
GO:0009065 biological process glutamine family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine famil (more detail) 26 NA Homo sapiens
TAX028507
GO:0061615 biological process glycolytic process through fructose 6 phosphate The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, oc (more detail) 26 NA Homo sapiens
TAX016546
GO:0006706 biological process steroid catabolic process The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyc (more detail) 26 NA Homo sapiens
WIG001314
Genes involved in Vif mediated degradation of APOBEC3G (more detail) 48 NA Homo sapiens
TAX015275
GO:0004623 molecular function phospholipase A2 activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. (more detail) 30 NA Homo sapiens
FOX000609
Genes in the cancer module 29 (more detail) 28 NA Homo sapiens
TAX016561
GO:0006734 biological process NADH metabolic process The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a co (more detail) 35 NA Homo sapiens
TAX020199
GO:0022627 cellular component cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol. (more detail) 46 NA Homo sapiens
WIG001055
Genes involved in p53 Dependent G1 DNA Damage Response (more detail) 53 NA Homo sapiens
TAX028510
GO:0061621 biological process canonical glycolysis The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokin (more detail) 25 NA Homo sapiens
TAX028556
GO:0061718 biological process glucose catabolic process to pyruvate The chemical reactions and pathways resulting in the breakdown of glucose, with the production of py (more detail) 25 NA Homo sapiens
TAX019724
GO:0019433 biological process triglyceride catabolic process The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of gl (more detail) 25 NA Homo sapiens
TAX016249
GO:0006308 biological process DNA catabolic process The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of (more detail) 25 NA Homo sapiens
TAX016562
GO:0006735 biological process NADH regeneration A metabolic process that generates a pool of NADH by the reduction of NAD+. (more detail) 25 NA Homo sapiens
WIG000717
Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 (more detail) 47 NA Homo sapiens
TAX000021
Genes annotated by the GO term GO:0009310. The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. (more detail) 27 NA Homo sapiens
MAX000484
Protein biosynthesis, transport or catabolism genes up regulated in hyperploid multiple myeloma (MM) compared to the non hyperploid MM samples. Hyperdiploid multiple myeloma (H-MM) is the most common form of myeloma. In this gene expression pro (more detail) 51 NA Homo sapiens
WIG000514
Fatty acid metabolism (more detail) 42 NA Homo sapiens
TAX019292
GO:0016896 molecular function exoribonuclease activity, producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residu (more detail) 32 NA Homo sapiens
WIG001056
Genes involved in p53 Independent G1/S DNA damage checkpoint (more detail) 49 NA Homo sapiens
IEI007019
Protein protein interactors of human gene KRT24 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KRT24 (SwissProt ID= (more detail) 50 17535438 Homo sapiens
TAX001383
Genes annotated by the GO term GO:0019787. Catalysis of ATP dependent isopeptide bond formation between the carboxy terminal residues of a small conjugating protein such as ubiquitin or a ubiquitin like protein, and a substrate lysine residue. (more detail) 50 NA Homo sapiens
WIG000633
Tryptophan metabolism (more detail) 38 NA Homo sapiens
WIG000739
Genes involved in CDK mediated phosphorylation and removal of Cdc6 (more detail) 47 NA Homo sapiens
WAG001303
Formation of the ternary complex, and subsequently, the 43S complex (more detail) 47 NA Homo sapiens
TAX001106
Genes annotated by the GO term GO:0004091. Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion. (more detail) 33 NA Homo sapiens
TAX001445
Genes annotated by the GO term GO:0004842. Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N ubiquityllysine. (more detail) 48 NA Homo sapiens
TAX017488
GO:0009072 biological process aromatic amino acid family metabolic process The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic (more detail) 39 NA Homo sapiens
TAX017656
GO:0009310 biological process amine catabolic process The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakl (more detail) 23 NA Homo sapiens
TAX023815
GO:0042402 biological process cellular biogenic amine catabolic process The chemical reactions and pathways occurring at the level of individual cells resulting in the brea (more detail) 23 NA Homo sapiens
TAX020843
GO:0031146 biological process SCF dependent proteasomal ubiquitin dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 23 NA Homo sapiens
WAG000996
Glycan structures degradation (more detail) 27 NA Homo sapiens
TAX000025
Genes annotated by the GO term GO:0009063. The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. (more detail) 25 NA Homo sapiens
TAX013292
GO:0000175 molecular function 3' 5' exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule. (more detail) 30 NA Homo sapiens
WAG000326
SCF beta TrCP mediated degradation of Emi1 (more detail) 44 NA Homo sapiens
TAX013348
GO:0000289 biological process nuclear transcribed mRNA poly(A) tail shortening Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. (more detail) 22 NA Homo sapiens
TAX025471
GO:0046135 biological process pyrimidine nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecul (more detail) 22 NA Homo sapiens
TAX020330
GO:0030149 biological process sphingolipid catabolic process The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of l (more detail) 22 NA Homo sapiens
IEI010655
Protein protein interactors of human gene PSMD5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMD5 (SwissProt ID= (more detail) 45 17535438 Homo sapiens
WAG001555
SCF(Skp2) mediated degradation of p27/p21 (more detail) 45 NA Homo sapiens
TAX016384
GO:0006515 biological process protein quality control for misfolded or incompletely synthesized proteins The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins. (more detail) 26 NA Homo sapiens
FOX000850
Genes in the cancer module 91 (more detail) 36 NA Homo sapiens
WAG000936
Vif mediated degradation of APOBEC3G (more detail) 43 NA Homo sapiens
WIG000822
Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) (more detail) 27 NA Homo sapiens
FOX000600
Genes in the cancer module 28 (more detail) 32 NA Homo sapiens
TAX023689
GO:0042135 biological process neurotransmitter catabolic process The chemical reactions and pathways resulting in the breakdown of any of a group of substances that (more detail) 21 NA Homo sapiens
TAX023849
GO:0042454 biological process ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside i (more detail) 21 NA Homo sapiens
TAX000734
Genes annotated by the GO term GO:0006401. The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5' phosphodiester linkage. (more detail) 23 NA Homo sapiens
TAX019583
GO:0019058 biological process viral life cycle A set of processes which all viruses follow to ensure survival; includes attachment and entry of the (more detail) 30 NA Homo sapiens
FOX000140
Neighborhood of GLTSCR2 Neighborhood of GLTSCR2 glioma tumor suppressor candidate region gene 2 in the GNF2 expression comp (more detail) 30 NA Homo sapiens
TAX001305
Genes annotated by the GO term GO:0004620. Catalysis of the hydrolysis of a glycerophospholipid. (more detail) 42 NA Homo sapiens
TAX023386
GO:0036452 cellular component ESCRT complex An endosomal sorting complex involved in membrane fission processes related to sorting of multivesic (more detail) 28 NA Homo sapiens
TAX028634
GO:0061912 biological process selective autophagy The macroautophagy process in which specific structures are targeted by the autophagy process. (more detail) 20 NA Homo sapiens
TAX025549
GO:0046386 biological process deoxyribose phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phospho (more detail) 20 NA Homo sapiens
TAX017484
GO:0009068 biological process aspartate family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate famil (more detail) 20 NA Homo sapiens
WIG000911
Genes involved in HS GAG degradation (more detail) 20 NA Homo sapiens
WIG000513
Ether lipid metabolism (more detail) 30 NA Homo sapiens
IEI010628
Protein protein interactors of human gene PSMA8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PSMA8 (SwissProt ID= (more detail) 33 17535438 Homo sapiens
TAX001201
Genes annotated by the GO term GO:0004553. Catalysis of the hydrolysis of any O glycosyl bond. (more detail) 36 NA Homo sapiens
TAX017641
GO:0009264 biological process deoxyribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound (more detail) 19 NA Homo sapiens
TAX024858
GO:0044804 biological process autophagy of nucleus A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucle (more detail) 19 NA Homo sapiens
TAX025485
GO:0046174 biological process polyol catabolic process The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing t (more detail) 19 NA Homo sapiens
TAX018854
GO:0016075 biological process rRNA catabolic process The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural (more detail) 19 NA Homo sapiens
WAG001346
Regulation of APC/C activators between G1/S and early anaphase (more detail) 19 NA Homo sapiens
TAX013474
GO:0000737 biological process DNA catabolic process, endonucleolytic The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of i (more detail) 19 NA Homo sapiens
WAG000466
APC/C:Cdc20 mediated degradation of mitotic proteins (more detail) 19 NA Homo sapiens
TAX024019
GO:0042788 cellular component polysomal ribosome A ribosome bound to mRNA that forms part of a polysome. (more detail) 29 NA Homo sapiens
TAX013407
GO:0000421 cellular component autophagosome membrane The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenou (more detail) 29 NA Homo sapiens
WAG000987
Cyanoamino acid metabolism (more detail) 29 NA Homo sapiens
FOX000553
Genes in the cancer module 221 (more detail) 29 NA Homo sapiens
IEI001062
Protein protein interactors of human gene ATP1A2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ATP1A2 (SwissProt ID (more detail) 32 17535438 Homo sapiens
TAX000066
Genes annotated by the GO term GO:0016052. The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. (more detail) 24 NA Homo sapiens
TAX033374
GO:1904292 biological process regulation of ERAD pathway Any process that modulates the frequency, rate or extent of ERAD pathway. (more detail) 27 NA Homo sapiens
WAG000906
Inactivation of APC/C via direct inhibition of the APC/C complex (more detail) 18 NA Homo sapiens
TAX017495
GO:0009083 biological process branched chain amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched (more detail) 18 NA Homo sapiens
TAX028590
GO:0061783 molecular function peptidoglycan muralytic activity A catalytic activity that contributes to the degradation of peptidoglycan. (more detail) 18 NA Homo sapiens
TAX023991
GO:0042744 biological process hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2). (more detail) 18 NA Homo sapiens
WAG000455
APC Cdc20 mediated degradation of Nek2A (more detail) 20 NA Homo sapiens
IEI006420
Protein protein interactors of human gene INSIG2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene INSIG2 (SwissProt ID (more detail) 36 17535438 Homo sapiens
TAX023309
GO:0036258 biological process multivesicular body assembly The aggregation, arrangement and bonding together of a set of components to form a multivesicular bo (more detail) 30 NA Homo sapiens
TAX029226
GO:0070979 biological process protein K11 linked ubiquitination A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubi (more detail) 28 NA Homo sapiens
WIG000880
Genes involved in Glycolysis (more detail) 28 NA Homo sapiens
FOX000516
Genes in the cancer module 184 (more detail) 28 NA Homo sapiens
TAX023308
GO:0036257 biological process multivesicular body organization A process that is carried out at the cellular level which results in the assembly, arrangement of co (more detail) 31 NA Homo sapiens
WIG000700
Genes involved in APC Cdc20 mediated degradation of Nek2A (more detail) 23 NA Homo sapiens
TAX000077
Genes annotated by the GO term GO:0044275. The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. (more detail) 23 NA Homo sapiens
TAX015274
GO:0004622 molecular function lysophospholipase activity Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate. (more detail) 23 NA Homo sapiens
TAX015868
GO:0005680 cellular component anaphase promoting complex A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby tr (more detail) 21 NA Homo sapiens
TAX015403
GO:0004806 molecular function triglyceride lipase activity Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate. (more detail) 21 NA Homo sapiens
WIG000701
Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B (more detail) 21 NA Homo sapiens
TAX024493
GO:0043649 biological process dicarboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic ac (more detail) 17 NA Homo sapiens
WAG001293
APC/C:Cdc20 mediated degradation of Cyclin B (more detail) 17 NA Homo sapiens
WIG000552
Linoleic acid metabolism (more detail) 29 NA Homo sapiens
TAX023990
GO:0042743 biological process hydrogen peroxide metabolic process The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byprod (more detail) 29 NA Homo sapiens
IEI004657
Protein protein interactors of human gene FBXO5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO5 (SwissProt ID= (more detail) 32 17535438 Homo sapiens
TAX013399
GO:0000407 cellular component phagophore assembly site Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machiner (more detail) 19 NA Homo sapiens
WIG000929
Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (more detail) 19 NA Homo sapiens
TAX031519
GO:0102567 molecular function phospholipase A2 activity (consuming 1,2 dipalmitoylphosphatidylcholine) Catalysis of the reaction: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn- (more detail) 19 NA Homo sapiens
TAX031520
GO:0102568 molecular function phospholipase A2 activity consuming 1,2 dioleoylphosphatidylethanolamine) Catalysis of the reaction: 1-18:1-2-18:1-phosphatidylethanolamine + H2O = 1-oleoyl-sn-glycero-3-phos (more detail) 19 NA Homo sapiens
TAX016403
GO:0006536 biological process glutamate metabolic process The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. (more detail) 30 NA Homo sapiens
MAX001953
Genes involved in free fatty acid oxidation; based on literature and sequence annotation resources and coverted to Affymetrix HG U133A probe sets. DNA microarrays can be used to identify gene expression changes characteristic of human disease. Thi (more detail) 22 NA Homo sapiens
IEI004041
Protein protein interactors of human gene EIF3CL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene EIF3CL (SwissProt ID (more detail) 28 17535438 Homo sapiens
WIG000409
Proteasome Complex Attachment of the ubiquitin peptide to proteins targets them for proteolytic degradation by a comple (more detail) 28 NA Homo sapiens
TAX013338
GO:0000272 biological process polysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of man (more detail) 16 NA Homo sapiens
WAG000074
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (more detail) 16 NA Homo sapiens
WAG000509
Phosphorylation of the APC/C (more detail) 16 NA Homo sapiens
TAX022285
GO:0034045 cellular component phagophore assembly site membrane A cellular membrane associated with the phagophore assembly site. (more detail) 16 NA Homo sapiens
TAX024192
GO:0043162 biological process ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently ta (more detail) 16 NA Homo sapiens
TAX025589
GO:0046475 biological process glycerophospholipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivati (more detail) 16 NA Homo sapiens
WIG001074
Genes involved in Phosphorylation of the APC/C (more detail) 18 NA Homo sapiens
TAX024688
GO:0044322 cellular component endoplasmic reticulum quality control compartment A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding a (more detail) 23 NA Homo sapiens
TAX023288
GO:0036152 biological process phosphatidylethanolamine acyl chain remodeling Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylat (more detail) 23 NA Homo sapiens
IEI011617
Protein protein interactors of human gene RPTN from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RPTN (SwissProt ID=Q (more detail) 26 17535438 Homo sapiens
TAX021453
GO:0032309 biological process icosanoid secretion The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell (more detail) 26 NA Homo sapiens
TAX017493
GO:0009081 biological process branched chain amino acid metabolic process The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, com (more detail) 21 NA Homo sapiens
WIG000531
Glycosaminoglycan degradation (more detail) 21 NA Homo sapiens
WIG000468
alpha Linolenic acid metabolism (more detail) 19 NA Homo sapiens
TAX020381
GO:0030214 biological process hyaluronan catabolic process The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurrin (more detail) 15 NA Homo sapiens
TAX022407
GO:0034310 biological process primary alcohol catabolic process The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcoho (more detail) 15 NA Homo sapiens
TAX029270
GO:0071044 biological process histone mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA). (more detail) 15 NA Homo sapiens
WAG000667
APC/C mediated degradation of cell cycle proteins (more detail) 15 NA Homo sapiens
TAX033418
GO:1904380 biological process endoplasmic reticulum mannose trimming Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control (more detail) 15 NA Homo sapiens
TAX022131
GO:0033539 biological process fatty acid beta oxidation using acyl CoA dehydrogenase A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which convert (more detail) 15 NA Homo sapiens
TAX022132
GO:0033540 biological process fatty acid beta oxidation using acyl CoA oxidase A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans (more detail) 15 NA Homo sapiens
TAX020196
GO:0022624 cellular component proteasome accessory complex A protein complex, that caps one or both ends of the proteasome core complex and regulates entry int (more detail) 17 NA Homo sapiens
FOX000713
Genes in the cancer module 417 (more detail) 22 NA Homo sapiens
TAX016386
GO:0006517 biological process protein deglycosylation The removal of sugar residues from a glycosylated protein. (more detail) 28 NA Homo sapiens
TAX033225
GO:1903963 biological process arachidonate transport The directed movement of an arachidonate into, out of or within a cell, or between cells, by means o (more detail) 23 NA Homo sapiens
IEI014062
Protein protein interactors of human gene TNRC6C from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TNRC6C (SwissProt ID (more detail) 23 17535438 Homo sapiens
TAX026462
GO:0050482 biological process arachidonic acid secretion The controlled release of arachidonic acid from a cell or a tissue. (more detail) 23 NA Homo sapiens
TAX023884
GO:0042537 biological process benzene containing compound metabolic process The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, co (more detail) 23 NA Homo sapiens
TAX033892
GO:1905354 cellular component exoribonuclease complex A protein complex which is capable of exoribonuclease activity. (more detail) 26 NA Homo sapiens
TAX023287
GO:0036151 biological process phosphatidylcholine acyl chain remodeling Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation r (more detail) 26 NA Homo sapiens
WAG000377
Ether lipid metabolism (more detail) 26 NA Homo sapiens
TAX013295
GO:0000178 cellular component exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuc (more detail) 26 NA Homo sapiens
WAG000392
Glycosaminoglycan degradation (more detail) 16 NA Homo sapiens
TAX017605
GO:0009214 biological process cyclic nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide (more detail) 14 NA Homo sapiens
TAX017511
GO:0009109 biological process coenzyme catabolic process The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprote (more detail) 14 NA Homo sapiens
TAX020741
GO:0030970 biological process retrograde protein transport, ER to cytosol The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytoso (more detail) 14 NA Homo sapiens
TAX023845
GO:0042447 biological process hormone catabolic process The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring s (more detail) 14 NA Homo sapiens
TAX032980
GO:1903513 biological process endoplasmic reticulum to cytosol transport The directed movement of substances from endoplasmic reticulum to cytosol. (more detail) 14 NA Homo sapiens
TAX020375
GO:0030207 biological process chondroitin sulfate catabolic process The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of (more detail) 14 NA Homo sapiens
TAX025533
GO:0046348 biological process amino sugar catabolic process The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing (more detail) 14 NA Homo sapiens
TAX019705
GO:0019377 biological process glycolipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-ac (more detail) 14 NA Homo sapiens
TAX024643
GO:0044247 biological process cellular polysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (more detail) 14 NA Homo sapiens
WIG001000
Genes involved in mRNA Decay by 5' to 3' Exoribonuclease (more detail) 14 NA Homo sapiens
TAX013251
GO:0000098 biological process sulfur amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, com (more detail) 14 NA Homo sapiens
TAX014793
GO:0003796 molecular function lysozyme activity Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D- (more detail) 14 NA Homo sapiens
TAX016250
GO:0006309 biological process apoptotic DNA fragmentation The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of (more detail) 14 NA Homo sapiens
TAX025736
GO:0046755 biological process viral budding A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral protein (more detail) 24 NA Homo sapiens
WIG000719
Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis (more detail) 25 NA Homo sapiens
TAX001049
Genes annotated by the GO term GO:0000151. A protein complex that includes a ubiquitin protein ligase (E3) and other proteins that may confer substrate specificity on the complex. (more detail) 25 NA Homo sapiens
WIG000731
Genes involved in Branched chain amino acid catabolism (more detail) 17 NA Homo sapiens
WIG000794
Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) (more detail) 17 NA Homo sapiens
WIG000768
Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (more detail) 17 NA Homo sapiens
TAX023285
GO:0036149 biological process phosphatidylinositol acyl chain remodeling Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation (more detail) 15 NA Homo sapiens
TAX024577
GO:0044036 biological process cell wall macromolecule metabolic process The chemical reactions and pathways involving macromolecules forming, or destined to form, part of t (more detail) 15 NA Homo sapiens
MAX001956
Genes involved in glycolysis; based on literature and sequence annotation resources and converted to Affymetrix HG U133A probe sets. DNA microarrays can be used to identify gene expression changes characteristic of human disease. Thi (more detail) 20 NA Homo sapiens
WIG000674
Genes involved in Acyl chain remodelling of PE (more detail) 20 NA Homo sapiens
TAX001304
Genes annotated by the GO term GO:0004623. Catalysis of the reaction: phosphatidylcholine + H2O = 1 acylglycerophosphocholine + a carboxylate. (more detail) 13 NA Homo sapiens
TAX016385
GO:0006516 biological process glycoprotein catabolic process The chemical reactions and pathways resulting in the breakdown of glycoproteins, any protein that co (more detail) 13 NA Homo sapiens
TAX016206
GO:0006244 biological process pyrimidine nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compoun (more detail) 13 NA Homo sapiens
TAX029635
GO:0071712 biological process ER associated misfolded protein catabolic process The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported fro (more detail) 13 NA Homo sapiens
TAX029259
GO:0071025 biological process RNA surveillance The set of processes involved in identifying and degrading defective or aberrant RNAs. (more detail) 13 NA Homo sapiens
TAX025615
GO:0046514 biological process ceramide catabolic process The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphing (more detail) 13 NA Homo sapiens
TAX017631
GO:0009251 biological process glucan catabolic process The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consistin (more detail) 13 NA Homo sapiens
TAX019325
GO:0016998 biological process cell wall macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a (more detail) 13 NA Homo sapiens
TAX017659
GO:0009313 biological process oligosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with b (more detail) 13 NA Homo sapiens
TAX023700
GO:0042159 biological process lipoprotein catabolic process The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble prot (more detail) 13 NA Homo sapiens
FAX003056
GSEA KEGG Lung Cancer Tissue Explants (Extracellular Vesicles) RNA Degradation Top 3 KEGG pathways enriched in lung cancer tissue extract extracellular vesicle particles compared (more detail) 13 32795414 Homo sapiens
IEI002180
Protein protein interactors of human gene CDC26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene CDC26 (SwissProt ID= (more detail) 23 17535438 Homo sapiens
TAX023594
GO:0039702 biological process viral budding via host ESCRT complex Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process. (more detail) 21 NA Homo sapiens
TAX001016
Genes annotated by the GO term GO:0000502. A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. (more detail) 21 NA Homo sapiens
WIG000673
Genes involved in Acyl chain remodelling of PC (more detail) 21 NA Homo sapiens
TAX020254
GO:0030014 cellular component CCR4 NOT complex The evolutionarily conserved CCR4-NOT complex is involved in several aspects of mRNA metabolism, inc (more detail) 16 NA Homo sapiens
WIG000578
Other glycan degradation (more detail) 16 NA Homo sapiens
TAX014902
GO:0003995 molecular function acyl CoA dehydrogenase activity Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. (more detail) 16 NA Homo sapiens
TAX023425
GO:0036507 biological process protein demannosylation The removal of one or more mannose residues from a mannosylated protein. (more detail) 19 NA Homo sapiens
TAX023426
GO:0036508 biological process protein alpha 1,2 demannosylation The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein. (more detail) 19 NA Homo sapiens
IEI004844
Protein protein interactors of human gene FNIP1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FNIP1 (SwissProt ID= (more detail) 14 17535438 Homo sapiens
WIG000676
Genes involved in Acyl chain remodelling of PI (more detail) 14 NA Homo sapiens
WAG001623
alpha Linolenic acid metabolism (more detail) 14 NA Homo sapiens
WIG000485
beta Alanine metabolism (more detail) 22 NA Homo sapiens
TAX017541
GO:0009143 biological process nucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compo (more detail) 12 NA Homo sapiens
TAX021073
GO:0031597 cellular component cytosolic proteasome complex A proteasome complex found in the cytosol of a cell. (more detail) 12 NA Homo sapiens
TAX017614
GO:0009223 biological process pyrimidine deoxyribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, (more detail) 12 NA Homo sapiens
TAX025469
GO:0046133 biological process pyrimidine ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside i (more detail) 12 NA Homo sapiens
TAX023988
GO:0042738 biological process exogenous drug catabolic process The chemical reactions and pathways resulting in the breakdown of a drug that has originated externa (more detail) 12 NA Homo sapiens
TAX017523
GO:0009125 biological process nucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a comp (more detail) 12 NA Homo sapiens
TAX017513
GO:0009111 biological process vitamin catabolic process The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unre (more detail) 12 NA Homo sapiens
TAX023784
GO:0042340 biological process keratan sulfate catabolic process The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglyc (more detail) 12 NA Homo sapiens
TAX025593
GO:0046479 biological process glycosphingolipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with (more detail) 12 NA Homo sapiens
TAX016049
GO:0005980 biological process glycogen catabolic process The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly b (more detail) 12 NA Homo sapiens
TAX016111
GO:0006068 biological process ethanol catabolic process The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, (more detail) 12 NA Homo sapiens
WIG000776
Genes involved in CS/DS degradation (more detail) 12 NA Homo sapiens
PEX000754
Peptidase M10: Matrixin The members of this family are enzymes that cleave peptides. These proteases require zinc for cataly (more detail) 12 NA Homo sapiens
WIG000796
Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) (more detail) 17 NA Homo sapiens
WIG000795
Genes involved in Destabilization of mRNA by KSRP (more detail) 17 NA Homo sapiens
IEI004615
Protein protein interactors of human gene FBXL15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXL15 (SwissProt ID (more detail) 20 17535438 Homo sapiens
WIG001503
Feeder Pathways for Glycolysis Feeder Pathways for Glycolysis (more detail) 15 NA Homo sapiens
TAX034224
GO:1990381 molecular function ubiquitin specific protease binding Interacting selectively and non-covalently with a ubiquitin-specific protease. (more detail) 15 NA Homo sapiens
TAX033001
GO:1903541 biological process regulation of exosomal secretion Any process that modulates the frequency, rate or extent of exosomal secretion. (more detail) 18 NA Homo sapiens
IEI000558
Protein protein interactors of human gene ANAPC16 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC16 (SwissProt I (more detail) 18 17535438 Homo sapiens
TAX000215
Genes annotated by the GO term GO:0019395. The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron accepting substance, by addition of oxygen or by removal of hydrogen. (more detail) 18 NA Homo sapiens
TAX024447
GO:0043562 biological process cellular response to nitrogen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 13 NA Homo sapiens
WIG000990
Genes involved in Mitochondrial Fatty Acid Beta Oxidation (more detail) 13 NA Homo sapiens
TAX016719
GO:0006995 biological process cellular response to nitrogen starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 13 NA Homo sapiens
TAX015211
GO:0004535 molecular function poly(A) specific ribonuclease activity Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP. (more detail) 13 NA Homo sapiens
TAX020834
GO:0031125 biological process rRNA 3' end processing Any process involved in forming the mature 3' end of an rRNA molecule. (more detail) 11 NA Homo sapiens
TAX018881
GO:0016127 biological process sterol catabolic process The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more (more detail) 11 NA Homo sapiens
TAX032169
GO:1901569 biological process fatty acid derivative catabolic process The chemical reactions and pathways resulting in the breakdown of fatty acid derivative. (more detail) 11 NA Homo sapiens
TAX032423
GO:1902222 biological process erythrose 4 phosphate/phosphoenolpyruvate family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolp (more detail) 11 NA Homo sapiens
TAX029261
GO:0071027 biological process nuclear RNA surveillance The set of processes involved in identifying and degrading defective or aberrant RNAs within the nuc (more detail) 11 NA Homo sapiens
IEI000557
Protein protein interactors of human gene ANAPC15 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC15 (SwissProt I (more detail) 11 17535438 Homo sapiens
TAX029528
GO:0071545 biological process inositol phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6 (more detail) 11 NA Homo sapiens
TAX032422
GO:1902221 biological process erythrose 4 phosphate/phosphoenolpyruvate family amino acid metabolic process The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino (more detail) 11 NA Homo sapiens
TAX016547
GO:0006707 biological process cholesterol catabolic process The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-o (more detail) 11 NA Homo sapiens
WIG000956
Genes involved in Keratan sulfate degradation (more detail) 11 NA Homo sapiens
WIG001118
Genes involved in Pyrimidine catabolism (more detail) 11 NA Homo sapiens
WIG000999
Genes involved in mRNA Decay by 3' to 5' Exoribonuclease (more detail) 11 NA Homo sapiens
TAX013347
GO:0000288 biological process nuclear transcribed mRNA catabolic process, deadenylation dependent decay A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordere (more detail) 11 NA Homo sapiens
TAX016573
GO:0006751 biological process glutathione catabolic process The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutam (more detail) 11 NA Homo sapiens
TAX016425
GO:0006558 biological process L phenylalanine metabolic process The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylp (more detail) 11 NA Homo sapiens
TAX016426
GO:0006559 biological process L phenylalanine catabolic process The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpro (more detail) 11 NA Homo sapiens
WIG001962
Mitochondrial LC Fatty Acid Beta Oxidation Mitochondrial LC-Fatty Acid Beta-Oxidation (more detail) 16 NA Homo sapiens
TAX021615
GO:0032527 biological process protein exit from endoplasmic reticulum The directed movement of proteins from the endoplasmic reticulum. (more detail) 19 NA Homo sapiens
TAX031123
GO:0098780 biological process response to mitochondrial depolarisation Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 19 NA Homo sapiens
IEI011206
Protein protein interactors of human gene RFFL from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RFFL (SwissProt ID=Q (more detail) 19 17535438 Homo sapiens
TAX019385
GO:0017110 molecular function nucleoside diphosphatase activity Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate. (more detail) 14 NA Homo sapiens
IEI011375
Protein protein interactors of human gene RNF103 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF103 (SwissProt ID (more detail) 14 17535438 Homo sapiens
WAG000802
N Glycan degradation (more detail) 14 NA Homo sapiens
FOX000669
Genes in the cancer module 360 (more detail) 14 NA Homo sapiens
IEI003569
Protein protein interactors of human gene DIS3L from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DIS3L (SwissProt ID= (more detail) 17 17535438 Homo sapiens
TAX016435
GO:0006568 biological process tryptophan metabolic process The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol- (more detail) 12 NA Homo sapiens
PEX001246
UCH: Ubiquitin carboxyl terminal hydrolase (more detail) 12 NA Homo sapiens
TAX016421
GO:0006554 biological process lysine catabolic process The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid. (more detail) 10 NA Homo sapiens
TAX022481
GO:0034427 biological process nuclear transcribed mRNA catabolic process, exonucleolytic, 3' 5' The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occu (more detail) 10 NA Homo sapiens
TAX017526
GO:0009128 biological process purine nucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a (more detail) 10 NA Homo sapiens
TAX025489
GO:0046185 biological process aldehyde catabolic process The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound wi (more detail) 10 NA Homo sapiens
TAX025496
GO:0046218 biological process indolalkylamine catabolic process The chemical reactions and pathways resulting in the breakdown of indolalkylamines, indole or indole (more detail) 10 NA Homo sapiens
TAX019681
GO:0019336 biological process phenol containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing (more detail) 10 NA Homo sapiens
TAX025440
GO:0046087 biological process cytidine metabolic process The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucl (more detail) 10 NA Homo sapiens
TAX017487
GO:0009071 biological process serine family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, (more detail) 10 NA Homo sapiens
TAX013513
GO:0000813 cellular component ESCRT I complex An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sor (more detail) 10 NA Homo sapiens
TAX025921
GO:0047372 molecular function acylglycerol lipase activity Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol. (more detail) 10 NA Homo sapiens
TAX032000
GO:1901072 biological process glucosamine containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds ( (more detail) 10 NA Homo sapiens
TAX023838
GO:0042436 biological process indole containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole ( (more detail) 10 NA Homo sapiens
WIG001114
Genes involved in Purine catabolism (more detail) 10 NA Homo sapiens
TAX016436
GO:0006569 biological process tryptophan catabolic process The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid (more detail) 10 NA Homo sapiens
TAX024001
GO:0042758 biological process long chain fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of long-chain fatty acids, a fatty ac (more detail) 10 NA Homo sapiens
TAX013349
GO:0000290 biological process deadenylation dependent decapping of nuclear transcribed mRNA Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a mini (more detail) 10 NA Homo sapiens
TAX017823
GO:0009972 biological process cytidine deamination The removal of amino group in the presence of water. (more detail) 10 NA Homo sapiens
TAX025763
GO:0046838 biological process phosphorylated carbohydrate dephosphorylation The process of removing a phosphate group from a phosphorylated carbohydrate, any organic compound b (more detail) 10 NA Homo sapiens
WIG000335
Glycolysis Pathway Glycolysis was one of the first metabolic pathways studied and is one of the best understood, in ter (more detail) 10 NA Homo sapiens
IEI012057
Protein protein interactors of human gene SESN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SESN2 (SwissProt ID= (more detail) 10 17535438 Homo sapiens
TAX023713
GO:0042178 biological process xenobiotic catabolic process The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound (more detail) 10 NA Homo sapiens
TAX021793
GO:0032802 biological process low density lipoprotein particle receptor catabolic process The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle (more detail) 10 NA Homo sapiens
WIG000913
Genes involved in Hyaluronan uptake and degradation (more detail) 10 NA Homo sapiens
TAX016193
GO:0006216 biological process cytidine catabolic process The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a wid (more detail) 10 NA Homo sapiens
TAX017150
GO:0008242 molecular function omega peptidase activity Catalysis of the removal of terminal peptide residues that are substituted, cyclized or linked by is (more detail) 15 NA Homo sapiens
TAX023284
GO:0036148 biological process phosphatidylglycerol acyl chain remodeling Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation (more detail) 18 NA Homo sapiens
TAX017610
GO:0009219 biological process pyrimidine deoxyribonucleotide metabolic process The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of (more detail) 18 NA Homo sapiens
IEI000556
Protein protein interactors of human gene ANAPC13 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ANAPC13 (SwissProt I (more detail) 13 17535438 Homo sapiens
TAX033375
GO:1904293 biological process negative regulation of ERAD pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway. (more detail) 13 NA Homo sapiens
TAX013294
GO:0000177 cellular component cytoplasmic exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity pr (more detail) 13 NA Homo sapiens
TAX013293
GO:0000176 cellular component nuclear exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuc (more detail) 16 NA Homo sapiens
FOX000700
Genes in the cancer module 401 (more detail) 16 NA Homo sapiens
WAG001613
Caffeine metabolism (more detail) 16 NA Homo sapiens
WIG000756
Genes involved in Chylomicron mediated lipid transport (more detail) 16 NA Homo sapiens
WIG000675
Genes involved in Acyl chain remodelling of PG (more detail) 16 NA Homo sapiens
TAX026404
GO:0050072 molecular function m7G(5')pppN diphosphatase activity Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosi (more detail) 11 NA Homo sapiens
TAX021790
GO:0032799 biological process low density lipoprotein receptor particle metabolic process The chemical reactions and pathways involving low-density lipoprotein receptors. (more detail) 11 NA Homo sapiens
TAX024888
GO:0045006 biological process DNA deamination The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosi (more detail) 11 NA Homo sapiens
WAG000408
Geraniol degradation (more detail) 11 NA Homo sapiens
MOX003439
Genes associated with Computational Drug Signature trans 1,2 Dihydro 1,2 naphthalenediol Genes associated with Computational Drug Signature trans-1,2-Dihydro-1,2-naphthalenediol, curated by (more detail) 11 25990557 Homo sapiens
TAX016420
GO:0006553 biological process lysine metabolic process The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid. (more detail) 11 NA Homo sapiens
TAX016376
GO:0006501 biological process C terminal protein lipidation The covalent attachment of a lipid group to the carboxy terminus of a protein. (more detail) 11 NA Homo sapiens
FOX000544
Genes in the cancer module 211 (more detail) 11 NA Homo sapiens
TAX000212
Genes annotated by the GO term GO:0006635. The metabolic oxidation of a long chain fatty acid by successive cycles of reactions during each of which the fatty acid is shortened by a two carbon fragment removed as acetyl coenzyme A. (more detail) 11 NA Homo sapiens
TAX029262
GO:0071028 biological process nuclear mRNA surveillance The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nu (more detail) 9 NA Homo sapiens
TAX023796
GO:0042363 biological process fat soluble vitamin catabolic process The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins (more detail) 9 NA Homo sapiens
TAX019706
GO:0019388 biological process galactose catabolic process The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto- (more detail) 9 NA Homo sapiens
TAX032253
GO:1901748 biological process leukotriene D4 metabolic process The chemical reactions and pathways involving leukotriene D4. (more detail) 9 NA Homo sapiens
TAX032254
GO:1901750 biological process leukotriene D4 biosynthetic process The chemical reactions and pathways resulting in the formation of leukotriene D4. (more detail) 9 NA Homo sapiens
TAX023831
GO:0042424 biological process catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically (more detail) 9 NA Homo sapiens
TAX019674
GO:0019317 biological process fucose catabolic process The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose). (more detail) 9 NA Homo sapiens
TAX025466
GO:0046130 biological process purine ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucle (more detail) 9 NA Homo sapiens
TAX025943
GO:0047498 molecular function calcium dependent phospholipase A2 activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. (more detail) 9 NA Homo sapiens
TAX023788
GO:0042354 biological process L fucose metabolic process The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in (more detail) 9 NA Homo sapiens
TAX023789
GO:0042355 biological process L fucose catabolic process The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose). (more detail) 9 NA Homo sapiens
TAX019765
GO:0019614 biological process catechol containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Cat (more detail) 9 NA Homo sapiens
TAX017556
GO:0009158 biological process ribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a (more detail) 9 NA Homo sapiens
TAX017566
GO:0009169 biological process purine ribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphat (more detail) 9 NA Homo sapiens
TAX023363
GO:0036374 molecular function glutathione hydrolase activity Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate. (more detail) 9 NA Homo sapiens
TAX025772
GO:0046855 biological process inositol phosphate dephosphorylation The process of removing a phosphate group from any mono- or polyphosphorylated inositol. (more detail) 9 NA Homo sapiens
TAX016405
GO:0006538 biological process glutamate catabolic process The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopen (more detail) 9 NA Homo sapiens
TAX014994
GO:0004126 molecular function cytidine deaminase activity Catalysis of the reaction: cytidine + H2O = uridine + NH3. (more detail) 9 NA Homo sapiens
TAX014054
GO:0002084 biological process protein depalmitoylation The removal of palymitoyl groups from a lipoprotein. (more detail) 9 NA Homo sapiens
TAX016157
GO:0006152 biological process purine nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family (more detail) 9 NA Homo sapiens
TAX016183
GO:0006198 biological process cAMP catabolic process The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, a (more detail) 9 NA Homo sapiens
WIG001309
Genes involved in Tryptophan catabolism (more detail) 9 NA Homo sapiens
IEI011994
Protein protein interactors of human gene SENP8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SENP8 (SwissProt ID= (more detail) 14 17535438 Homo sapiens
WEX000006
Arginine Metabolism The genes related to arginine metabolism (metabolism) in tumor, immune, stroma using next-generation (more detail) 14 NA Homo sapiens
WIG000677
Genes involved in Acyl chain remodelling of PS (more detail) 14 NA Homo sapiens
MOX010842
Genes associated with Computational Drug Signature CHEMBL475540 Genes associated with Computational Drug Signature CHEMBL475540, curated by the Drug Signature Datab (more detail) 14 25990557 Homo sapiens
TAX018792
GO:0015929 molecular function hexosaminidase activity Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) re (more detail) 12 NA Homo sapiens
TAX017338
GO:0008540 cellular component proteasome regulatory particle, base subcomplex The subcomplex of the proteasome regulatory particle that directly associates with the proteasome co (more detail) 12 NA Homo sapiens
TAX022445
GO:0034370 biological process triglyceride rich lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein p (more detail) 12 NA Homo sapiens
TAX023431
GO:0036513 cellular component Derlin 1 retrotranslocation complex A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degra (more detail) 12 NA Homo sapiens
TAX022524
GO:0034497 biological process protein localization to phagophore assembly site Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PA (more detail) 12 NA Homo sapiens
TAX033003
GO:1903543 biological process positive regulation of exosomal secretion Any process that activates or increases the frequency, rate or extent of exosomal secretion. (more detail) 15 NA Homo sapiens
IEI003380
Protein protein interactors of human gene DCUN1D5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DCUN1D5 (SwissProt I (more detail) 15 17535438 Homo sapiens
TAX032144
GO:1901524 biological process regulation of mitophagy Any process that modulates the frequency, rate or extent of macromitophagy. (more detail) 15 NA Homo sapiens
TAX015216
GO:0004551 molecular function nucleotide diphosphatase activity Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides. (more detail) 15 NA Homo sapiens
FOX000524
Genes in the cancer module 194 (more detail) 15 NA Homo sapiens
TAX001101
Genes annotated by the GO term GO:0019200. Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule. (more detail) 15 NA Homo sapiens
TAX016452
GO:0006586 biological process indolalkylamine metabolic process The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives contain (more detail) 15 NA Homo sapiens
TAX014988
GO:0004115 molecular function 3',5' cyclic AMP phosphodiesterase activity Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate. (more detail) 15 NA Homo sapiens
TAX031099
GO:0098734 biological process macromolecule depalmitoylation The removal of palymitoyl groups from a macromolecule. (more detail) 10 NA Homo sapiens
TAX028786
GO:0070189 biological process kynurenine metabolic process The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine. (more detail) 10 NA Homo sapiens
TAX017292
GO:0008474 molecular function palmitoyl (protein) hydrolase activity Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein. (more detail) 10 NA Homo sapiens
TAX031043
GO:0098599 molecular function palmitoyl hydrolase activity Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate. (more detail) 10 NA Homo sapiens
TAX001163
Genes annotated by the GO term GO:0008417. Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid. (more detail) 10 NA Homo sapiens
TAX022498
GO:0034450 molecular function ubiquitin ubiquitin ligase activity Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction (more detail) 13 NA Homo sapiens
TAX033376
GO:1904294 biological process positive regulation of ERAD pathway Any process that activates or increases the frequency, rate or extent of ERAD pathway. (more detail) 13 NA Homo sapiens
TAX033307
GO:1904152 biological process regulation of retrograde protein transport, ER to cytosol Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cyto (more detail) 13 NA Homo sapiens
TAX001076
Genes annotated by the GO term GO:0004177. Catalysis of the hydrolysis of N terminal amino acid residues from oligopeptides or polypeptides. (more detail) 13 NA Homo sapiens
PEX000151
PDEase I: 3'5' cyclic nucleotide phosphodiesterase (more detail) 13 NA Homo sapiens
TAX027452
GO:0052805 biological process imidazole containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic (more detail) 8 NA Homo sapiens
TAX019802
GO:0019773 cellular component proteasome core complex, alpha subunit complex The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. (more detail) 8 NA Homo sapiens
TAX023716
GO:0042182 biological process ketone catabolic process The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compou (more detail) 8 NA Homo sapiens
TAX018887
GO:0016139 biological process glycoside catabolic process The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a g (more detail) 8 NA Homo sapiens
TAX024890
GO:0045008 biological process depyrimidination The disruption of the bond between the sugar in the backbone and the C or T base, causing the base t (more detail) 8 NA Homo sapiens
TAX022446
GO:0034371 biological process chylomicron remodeling The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydr (more detail) 8 NA Homo sapiens
TAX023828
GO:0042420 biological process dopamine catabolic process The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotra (more detail) 8 NA Homo sapiens
TAX022518
GO:0034475 biological process U4 snRNA 3' end processing Any process involved in forming the mature 3' end of a U4 snRNA molecule. (more detail) 8 NA Homo sapiens
TAX021072
GO:0031595 cellular component nuclear proteasome complex A proteasome found in the nucleus of a cell. (more detail) 8 NA Homo sapiens
TAX017188
GO:0008300 biological process isoprenoid catabolic process The chemical reactions and pathways resulting in the breakdown of any isoprenoid compound, isoprene (more detail) 8 NA Homo sapiens
TAX017596
GO:0009204 biological process deoxyribonucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate (more detail) 8 NA Homo sapiens
PEX000430
Acyl CoA dh 1: Acyl CoA dehydrogenase, C terminal domain C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle. (more detail) 8 NA Homo sapiens
PEX000542
Acyl CoA dh N: Acyl CoA dehydrogenase, N terminal domain The N-terminal domain of Acyl-CoA dehydrogenase is an all-alpha domain. (more detail) 8 NA Homo sapiens
TAX016394
GO:0006527 biological process arginine catabolic process The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidami (more detail) 8 NA Homo sapiens
WAG000914
Phenylalanine and tyrosine catabolism (more detail) 8 NA Homo sapiens
MOX014659
Genes associated with Computational Drug Signature Psoralen Genes associated with Computational Drug Signature Psoralen, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
PEX001793
Acyl CoA dh M: Acyl CoA dehydrogenase, middle domain Central domain of Acyl-CoA dehydrogenase has a beta-barrel fold. (more detail) 8 NA Homo sapiens
TAX015039
GO:0004300 molecular function enoyl CoA hydratase activity Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O. (more detail) 8 NA Homo sapiens
TAX013702
GO:0001561 biological process fatty acid alpha oxidation A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not deg (more detail) 8 NA Homo sapiens
TAX016415
GO:0006548 biological process histidine catabolic process The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol- (more detail) 8 NA Homo sapiens
TAX032014
GO:1901096 biological process regulation of autophagosome maturation Any process that modulates the frequency, rate or extent of autophagosome maturation. (more detail) 11 NA Homo sapiens
IEI005102
Protein protein interactors of human gene GCAT from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GCAT (SwissProt ID=O (more detail) 11 17535438 Homo sapiens
WIG000368
Reversal of Insulin Resistance by Leptin The insulin resistance of type II diabetes appears to be caused in part by the presence of high leve (more detail) 11 NA Homo sapiens
WAG001288
Chylomicron mediated lipid transport (more detail) 11 NA Homo sapiens
WIG001768
Lysine Degradation in Human Liver Lysine Degradation in Human Liver (more detail) 11 NA Homo sapiens
TAX017455
GO:0008970 molecular function phospholipase A1 activity Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate. (more detail) 9 NA Homo sapiens
IEI013853
Protein protein interactors of human gene TMEM160 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TMEM160 (SwissProt I (more detail) 9 17535438 Homo sapiens
TAX034836
GO:2000644 biological process regulation of receptor catabolic process Any process that modulates the frequency, rate or extent of receptor catabolic process. (more detail) 9 NA Homo sapiens
PEX002570
zf RING 2: Ring finger domain (more detail) 9 NA Homo sapiens
PEX001660
HECT: HECT domain (ubiquitin transferase) The name HECT comes from Homologous to the E6-AP Carboxyl Terminus. (more detail) 9 NA Homo sapiens
MEX000059
Genes associated with Approved Drug carmustine Genes associated with Approved Drug carmustine, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
TAX015962
GO:0005838 cellular component proteasome regulatory particle A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex rec (more detail) 9 NA Homo sapiens
WIG000551
Limonene and pinene degradation (more detail) 9 NA Homo sapiens
IEI014635
Protein protein interactors of human gene UBXN4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBXN4 (SwissProt ID= (more detail) 12 17535438 Homo sapiens
IEI000112
Protein protein interactors of human gene ACADSB from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ACADSB (SwissProt ID (more detail) 12 17535438 Homo sapiens
TAX027189
GO:0051787 molecular function misfolded protein binding Interacting selectively and non-covalently with a misfolded protein. (more detail) 12 NA Homo sapiens
TAX021012
GO:0031464 cellular component Cul4A RING E3 ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form (more detail) 12 NA Homo sapiens
MAX003000
Subunits of the anaphase promoting complex (APC). Genomic instability can be found in most cancer cells. Cell proliferation is under tight control to (more detail) 12 NA Homo sapiens
MOX004782
Genes associated with Computational Drug Signature tranylcypromine Genes associated with Computational Drug Signature tranylcypromine, curated by the Drug Signature Da (more detail) 12 25990557 Homo sapiens
TAX013280
GO:0000153 cellular component cytoplasmic ubiquitin ligase complex A ubiquitin ligase complex found in the cytoplasm. (more detail) 12 NA Homo sapiens
TAX025477
GO:0046149 biological process pigment catabolic process The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particul (more detail) 7 NA Homo sapiens
TAX023706
GO:0042167 biological process heme catabolic process The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complex (more detail) 7 NA Homo sapiens
TAX017984
GO:0010587 biological process miRNA catabolic process The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single (more detail) 7 NA Homo sapiens
TAX017632
GO:0009253 biological process peptidoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of (more detail) 7 NA Homo sapiens
TAX018856
GO:0016078 biological process tRNA catabolic process The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of rel (more detail) 7 NA Homo sapiens
TAX025659
GO:0046604 biological process positive regulation of mitotic centrosome separation Any process that activates or increases the frequency, rate or extent of centrosome separation. (more detail) 7 NA Homo sapiens
TAX034216
GO:1990316 cellular component Atg1/ULK1 kinase complex A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along w (more detail) 7 NA Homo sapiens
TAX017532
GO:0009134 biological process nucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compou (more detail) 7 NA Homo sapiens
TAX024489
GO:0043633 biological process polyadenylation dependent RNA catabolic process The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by init (more detail) 7 NA Homo sapiens
TAX021933
GO:0033015 biological process tetrapyrrole catabolic process The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments cont (more detail) 7 NA Homo sapiens
TAX023179
GO:0035973 biological process aggrephagy Selective degradation of protein aggregates by macroautophagy. (more detail) 7 NA Homo sapiens
TAX019713
GO:0019405 biological process alditol catabolic process The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol d (more detail) 7 NA Homo sapiens
TAX017339
GO:0008541 cellular component proteasome regulatory particle, lid subcomplex The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added o (more detail) 7 NA Homo sapiens
IEI007641
Protein protein interactors of human gene MAP1LC3B2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MAP1LC3B2 (SwissProt (more detail) 7 17535438 Homo sapiens
PEX002507
RNase PH: 3' exoribonuclease family, domain 1 This family includes 3-5 exoribonucleases. Ribonuclease PH contains a single copy of this domain, a (more detail) 7 NA Homo sapiens
TAX015316
GO:0004679 molecular function AMP activated protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the pres (more detail) 7 NA Homo sapiens
TAX016084
GO:0006030 biological process chitin metabolic process The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1- (more detail) 7 NA Homo sapiens
WAG000334
mitochondrial fatty acid beta oxidation of saturated fatty acids (more detail) 7 NA Homo sapiens
MOX016010
Genes associated with Computational Drug Signature iproniazid Genes associated with Computational Drug Signature iproniazid, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
TAX015149
GO:0004465 molecular function lipoprotein lipase activity Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacyl (more detail) 7 NA Homo sapiens
TAX016085
GO:0006032 biological process chitin catabolic process The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide co (more detail) 7 NA Homo sapiens
WIG001415
Cyclophosphamide Pathway, Pharmacokinetics Model human liver cell showing genes involved in the metabolism of cyclophosphamide. (more detail) 7 NA Homo sapiens
WIG000706
Genes involved in Apoptosis induced DNA fragmentation (more detail) 7 NA Homo sapiens
TAX013336
GO:0000270 biological process peptidoglycan metabolic process The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates foun (more detail) 7 NA Homo sapiens
MOX013168
Genes associated with Computational Drug Signature iproniazid Genes associated with Computational Drug Signature iproniazid, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
TAX016418
GO:0006551 biological process leucine metabolic process The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid. (more detail) 7 NA Homo sapiens
MOX002598
Genes associated with Computational Drug Signature 126861 72 1 Genes associated with Computational Drug Signature 126861-72-1, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
PEX001617
Cullin: Cullin family (more detail) 7 NA Homo sapiens
PEX000832
Proteasome A N: Proteasome subunit A N terminal signature This domain is conserved in the A subunits of the proteasome complex proteins. (more detail) 7 NA Homo sapiens
PEX002651
Asp: Eukaryotic aspartyl protease Aspartyl (acid) proteases include pepsins, cathepsins, and renins. Two-domain structure, probably a (more detail) 7 NA Homo sapiens
TAX016595
GO:0006787 biological process porphyrin containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of any member of a large group of der (more detail) 7 NA Homo sapiens
MOX004765
Genes associated with Computational Drug Signature Ticrynafen Genes associated with Computational Drug Signature Ticrynafen, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
MOX001925
Genes associated with Computational Drug Signature Germacrone Genes associated with Computational Drug Signature Germacrone, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
TAX015230
GO:0004568 molecular function chitinase activity Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of c (more detail) 7 NA Homo sapiens
TAX022305
GO:0034098 cellular component VCP NPL4 UFD1 AAA ATPase complex A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation subst (more detail) 10 NA Homo sapiens
TAX021065
GO:0031588 cellular component nucleotide activated protein kinase complex A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be (more detail) 10 NA Homo sapiens
TAX030778
GO:0097267 biological process omega hydroxylase P450 pathway The chemical reactions and pathways by which arachidonic acid is converted to other compounds initia (more detail) 10 NA Homo sapiens
TAX017991
GO:0010603 biological process regulation of cytoplasmic mRNA processing body assembly Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bondin (more detail) 10 NA Homo sapiens
TAX025932
GO:0047429 molecular function nucleoside triphosphate diphosphatase activity Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide. (more detail) 10 NA Homo sapiens
MOX004370
Genes associated with Computational Drug Signature minoxidil Genes associated with Computational Drug Signature minoxidil, curated by the Drug Signature Database (more detail) 10 25990557 Homo sapiens
TAX016230
GO:0006285 biological process base excision repair, AP site formation The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recog (more detail) 10 NA Homo sapiens
MOX003384
Genes associated with Computational Drug Signature monohydroxymethoxychlor Genes associated with Computational Drug Signature monohydroxymethoxychlor, curated by the Drug Sign (more detail) 10 25990557 Homo sapiens
WIG000973
Genes involved in Membrane binding and targetting of GAG proteins (more detail) 10 NA Homo sapiens
WIG000627
Taurine and hypotaurine metabolism (more detail) 10 NA Homo sapiens
WAG000014
reversal of insulin resistance by leptin The insulin resistance of type II diabetes appears to be caused in part by the presence of high leve (more detail) 10 NA Homo sapiens
TAX016414
GO:0006547 biological process histidine metabolic process The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. (more detail) 10 NA Homo sapiens
IEI005705
Protein protein interactors of human gene HAPLN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene HAPLN1 (SwissProt ID (more detail) 8 17535438 Homo sapiens
MOX015063
Genes associated with Computational Drug Signature selegiline Genes associated with Computational Drug Signature selegiline, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
MOX015241
Genes associated with Computational Drug Signature sulpiride Genes associated with Computational Drug Signature sulpiride, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
TAX017038
GO:0008061 molecular function chitin binding Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of beta-( (more detail) 8 NA Homo sapiens
MEX000025
Genes associated with Approved Drug allopurinol Genes associated with Approved Drug allopurinol, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
TAX016114
GO:0006072 biological process glycerol 3 phosphate metabolic process The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycer (more detail) 8 NA Homo sapiens
MOX012020
Genes associated with Computational Drug Signature clopidogrel Genes associated with Computational Drug Signature clopidogrel, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
TAX016531
GO:0006689 biological process ganglioside catabolic process The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosacch (more detail) 6 NA Homo sapiens
TAX014896
GO:0003988 molecular function acetyl CoA C acyltransferase activity Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA. (more detail) 6 NA Homo sapiens
TAX024490
GO:0043634 biological process polyadenylation dependent ncRNA catabolic process The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, (more detail) 6 NA Homo sapiens
WAG000294
Lysine catabolism (more detail) 6 NA Homo sapiens
MEX000076
Genes associated with Approved Drug ciprofloxacin Genes associated with Approved Drug ciprofloxacin, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
TAX016527
GO:0006685 biological process sphingomyelin catabolic process The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl (more detail) 6 NA Homo sapiens
TAX025455
GO:0046113 biological process nucleobase catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base t (more detail) 6 NA Homo sapiens
TAX025944
GO:0047499 molecular function calcium independent phospholipase A2 activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. (more detail) 6 NA Homo sapiens
TAX014904
GO:0003997 molecular function acyl CoA oxidase activity Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide. (more detail) 6 NA Homo sapiens
IEI013541
Protein protein interactors of human gene TECPR2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TECPR2 (SwissProt ID (more detail) 6 17535438 Homo sapiens
TAX023373
GO:0036402 molecular function proteasome activating ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrat (more detail) 6 NA Homo sapiens
TAX029263
GO:0071029 biological process nuclear ncRNA surveillance The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the n (more detail) 6 NA Homo sapiens
TAX029277
GO:0071051 biological process polyadenylation dependent snoRNA 3' end processing Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylati (more detail) 6 NA Homo sapiens
TAX019761
GO:0019563 biological process glycerol catabolic process The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sw (more detail) 6 NA Homo sapiens
TAX025591
GO:0046477 biological process glycosylceramide catabolic process The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound fo (more detail) 6 NA Homo sapiens
PEX002476
Hemopexin: Hemopexin Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur (more detail) 6 NA Homo sapiens
PEX000244
PG binding 1: Putative peptidoglycan binding domain This domain is composed of three alpha helices 1. This domain is found at the N or C terminus of a (more detail) 6 NA Homo sapiens
WAG001361
Tryptophan catabolism (more detail) 6 NA Homo sapiens
WAG000540
Valine catabolism (more detail) 6 NA Homo sapiens
WIG001418
Ifosfamide Pathway, Pharmacokinetics Model human liver cell showing genes involved in the metabolism of ifosfamide. (more detail) 6 NA Homo sapiens
MOX001931
Genes associated with Computational Drug Signature modafinil Genes associated with Computational Drug Signature modafinil, curated by the Drug Signature Database (more detail) 6 25990557 Homo sapiens
TAX019000
GO:0016406 molecular function carnitine O acyltransferase activity Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule. (more detail) 6 NA Homo sapiens
TAX019334
GO:0017014 biological process protein nitrosylation The covalent addition of a nitric oxide group to an amino acid within a protein. (more detail) 6 NA Homo sapiens
TAX018872
GO:0016115 biological process terpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class (more detail) 6 NA Homo sapiens
MOX015229
Genes associated with Computational Drug Signature SULFADOXINE Genes associated with Computational Drug Signature SULFADOXINE, curated by the Drug Signature Databa (more detail) 6 25990557 Homo sapiens
WAG000210
Caprolactam degradation (more detail) 6 NA Homo sapiens
MOX001126
Genes associated with Computational Drug Signature Torasemide Genes associated with Computational Drug Signature Torasemide, curated by the Drug Signature Databas (more detail) 6 25990557 Homo sapiens
MOX009556
Genes associated with Computational Drug Signature CHEMBL306412 Genes associated with Computational Drug Signature CHEMBL306412, curated by the Drug Signature Datab (more detail) 6 25990557 Homo sapiens
TAX016461
GO:0006598 biological process polyamine catabolic process The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound c (more detail) 6 NA Homo sapiens
TAX017553
GO:0009155 biological process purine deoxyribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a comp (more detail) 6 NA Homo sapiens
TAX017585
GO:0009191 biological process ribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a co (more detail) 6 NA Homo sapiens
TAX020573
GO:0030579 biological process ubiquitin dependent SMAD protein catabolic process The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquit (more detail) 6 NA Homo sapiens
TAX020802
GO:0031087 biological process deadenylation independent decapping of nuclear transcribed mRNA Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening. (more detail) 6 NA Homo sapiens
PEX002036
Peptidase M1: Peptidase family M1 domain Members of this family are aminopeptidases. The members differ widely in specificity, hydrolysing a (more detail) 6 NA Homo sapiens
MOX014423
Genes associated with Computational Drug Signature PERHEXILINE Genes associated with Computational Drug Signature PERHEXILINE, curated by the Drug Signature Databa (more detail) 6 25990557 Homo sapiens
IEI005399
Protein protein interactors of human gene GPC6 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GPC6 (SwissProt ID=Q (more detail) 6 17535438 Homo sapiens
TAX015715
GO:0005324 molecular function long chain fatty acid transporter activity Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chai (more detail) 6 NA Homo sapiens
TAX019680
GO:0019323 biological process pentose catabolic process The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with (more detail) 6 NA Homo sapiens
PEX001858
Atg8: Autophagy protein Atg8 ubiquitin like Light chain 3 is proposed to function primarily as a subunit of microtubule associated proteins 1A a (more detail) 6 NA Homo sapiens
IEI001271
Protein protein interactors of human gene BCKDHA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BCKDHA (SwissProt ID (more detail) 6 17535438 Homo sapiens
WAG000689
Leucine catabolism (more detail) 6 NA Homo sapiens
TAX016438
GO:0006572 biological process tyrosine catabolic process The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, (more detail) 6 NA Homo sapiens
TAX017544
GO:0009146 biological process purine nucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a (more detail) 6 NA Homo sapiens
TAX017994
GO:0010606 biological process positive regulation of cytoplasmic mRNA processing body assembly Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bondin (more detail) 6 NA Homo sapiens
TAX019467
GO:0018119 biological process peptidyl cysteine S nitrosylation The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in (more detail) 6 NA Homo sapiens
PEX002615
RNase PH C: 3' exoribonuclease family, domain 2 This family includes 3-5 exoribonucleases. Ribonuclease PH contains a single copy of this domain, a (more detail) 6 NA Homo sapiens
TAX023832
GO:0042426 biological process choline catabolic process The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylam (more detail) 6 NA Homo sapiens
TAX030037
GO:0072526 biological process pyridine containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i. (more detail) 6 NA Homo sapiens
TAX013409
GO:0000423 biological process mitophagy Degradation of a mitochondrion by macroautophagy. (more detail) 6 NA Homo sapiens
TAX029266
GO:0071035 biological process nuclear polyadenylation dependent rRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a rib (more detail) 6 NA Homo sapiens
TAX029272
GO:0071046 biological process nuclear polyadenylation dependent ncRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a non (more detail) 6 NA Homo sapiens
TAX020255
GO:0030015 cellular component CCR4 NOT core complex The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, (more detail) 6 NA Homo sapiens
TAX030843
GO:0097413 cellular component Lewy body Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosp (more detail) 6 NA Homo sapiens
TAX033308
GO:1904153 biological process negative regulation of retrograde protein transport, ER to cytosol Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein tran (more detail) 9 NA Homo sapiens
TAX033553
GO:1904667 biological process negative regulation of ubiquitin protein ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligas (more detail) 9 NA Homo sapiens
TAX019246
GO:0016832 molecular function aldehyde lyase activity Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl gro (more detail) 9 NA Homo sapiens
TAX022916
GO:0035520 biological process monoubiquitinated protein deubiquitination The removal of the ubiquitin group from a monoubiquitinated protein. (more detail) 9 NA Homo sapiens
IEI004652
Protein protein interactors of human gene FBXO42 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FBXO42 (SwissProt ID (more detail) 9 17535438 Homo sapiens
TAX027416
GO:0052646 biological process alditol phosphate metabolic process The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alco (more detail) 9 NA Homo sapiens
IEI014238
Protein protein interactors of human gene TRIM34 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TRIM34 (SwissProt ID (more detail) 9 17535438 Homo sapiens
TAX020953
GO:0031371 cellular component ubiquitin conjugating enzyme complex Any complex that possesses ubiquitin conjugating enzyme activity. (more detail) 9 NA Homo sapiens
IEI013421
Protein protein interactors of human gene TBC1D2B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBC1D2B (SwissProt I (more detail) 9 17535438 Homo sapiens
IEI011435
Protein protein interactors of human gene RNF26 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF26 (SwissProt ID= (more detail) 9 17535438 Homo sapiens
IEI012985
Protein protein interactors of human gene SRPX from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SRPX (SwissProt ID=P (more detail) 9 17535438 Homo sapiens
TAX019781
GO:0019695 biological process choline metabolic process The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino al (more detail) 9 NA Homo sapiens
TAX025438
GO:0046085 biological process adenosine metabolic process The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found wi (more detail) 9 NA Homo sapiens
MOX007451
Genes associated with Computational Drug Signature caffeine Genes associated with Computational Drug Signature caffeine, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens
MOX002838
Genes associated with Computational Drug Signature CTK2F5402 Genes associated with Computational Drug Signature CTK2F5402, curated by the Drug Signature Database (more detail) 9 25990557 Homo sapiens
MOX001244
Genes associated with Computational Drug Signature ISOPROTURON Genes associated with Computational Drug Signature ISOPROTURON, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
MOX010669
Genes associated with Computational Drug Signature CHEMBL448246 Genes associated with Computational Drug Signature CHEMBL448246, curated by the Drug Signature Datab (more detail) 9 25990557 Homo sapiens
MOX003167
Genes associated with Computational Drug Signature Almotriptan Genes associated with Computational Drug Signature Almotriptan, curated by the Drug Signature Databa (more detail) 9 25990557 Homo sapiens
MEX000526
Genes associated with Approved Drug selegiline Genes associated with Approved Drug selegiline, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
MEX000624
Genes associated with Approved Drug clopidogrel Genes associated with Approved Drug clopidogrel, curated by the Drug Signature Database (DSigDB). (more detail) 9 25990557 Homo sapiens
WIG000324
Feeder Pathways for Glycolysis The glycolytic pathway begins with the simple sugar glucose and leads to pyruvate and eventually the (more detail) 9 NA Homo sapiens
TAX014815
GO:0003857 molecular function 3 hydroxyacyl CoA dehydrogenase activity Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+). (more detail) 9 NA Homo sapiens
MOX012341
Genes associated with Computational Drug Signature diphenhydramine Genes associated with Computational Drug Signature diphenhydramine, curated by the Drug Signature Da (more detail) 9 25990557 Homo sapiens
MOX004698
Genes associated with Computational Drug Signature sulfaphenazole Genes associated with Computational Drug Signature sulfaphenazole, curated by the Drug Signature Dat (more detail) 9 25990557 Homo sapiens
IEI002882
Protein protein interactors of human gene COX11 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene COX11 (SwissProt ID= (more detail) 7 17535438 Homo sapiens
IEI004444
Protein protein interactors of human gene FAM120B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene FAM120B (SwissProt I (more detail) 7 17535438 Homo sapiens
TAX022701
GO:0035032 cellular component phosphatidylinositol 3 kinase complex, class III A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinas (more detail) 7 NA Homo sapiens
TAX028903
GO:0070383 biological process DNA cytosine deamination The removal of an amino group from a cytosine residue in DNA, forming a uracil residue. (more detail) 7 NA Homo sapiens
MOX011430
Genes associated with Computational Drug Signature CHEMBL574589 Genes associated with Computational Drug Signature CHEMBL574589, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
MOX012707
Genes associated with Computational Drug Signature fluconazole Genes associated with Computational Drug Signature fluconazole, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MEX000309
Genes associated with Approved Drug sulfaphenazole Genes associated with Approved Drug sulfaphenazole, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MEX000052
Genes associated with Approved Drug busulfan Genes associated with Approved Drug busulfan, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX002434
Genes associated with Computational Drug Signature 4450 98 0 Genes associated with Computational Drug Signature 4450-98-0, curated by the Drug Signature Database (more detail) 7 25990557 Homo sapiens
MOX013311
Genes associated with Computational Drug Signature KT 6528 Genes associated with Computational Drug Signature KT 6528, curated by the Drug Signature Database ( (more detail) 7 25990557 Homo sapiens
MOX005257
Genes associated with Computational Drug Signature (R) ( ) Rolipram Genes associated with Computational Drug Signature (R)-(-)-Rolipram, curated by the Drug Signature D (more detail) 7 25990557 Homo sapiens
MOX011982
Genes associated with Computational Drug Signature Cipemastat Genes associated with Computational Drug Signature Cipemastat, curated by the Drug Signature Databas (more detail) 7 25990557 Homo sapiens
MOX013067
Genes associated with Computational Drug Signature IBMX Genes associated with Computational Drug Signature IBMX, curated by the Drug Signature Database (DSi (more detail) 7 25990557 Homo sapiens
WAG000866
Aspartate, asparagine, glutamate, and glutamine metabolism (more detail) 7 NA Homo sapiens
MEX000119
Genes associated with Approved Drug etidronic acid Genes associated with Approved Drug etidronic acid, curated by the Drug Signature Database (DSigDB). (more detail) 7 25990557 Homo sapiens
MOX006904
Genes associated with Computational Drug Signature allopurinol Genes associated with Computational Drug Signature allopurinol, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX014787
Genes associated with Computational Drug Signature Remoxipride Genes associated with Computational Drug Signature Remoxipride, curated by the Drug Signature Databa (more detail) 7 25990557 Homo sapiens
MOX011418
Genes associated with Computational Drug Signature CHEMBL573935 Genes associated with Computational Drug Signature CHEMBL573935, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
MOX011447
Genes associated with Computational Drug Signature CHEMBL575896 Genes associated with Computational Drug Signature CHEMBL575896, curated by the Drug Signature Datab (more detail) 7 25990557 Homo sapiens
MOX000206
Genes associated with Computational Drug Signature 2 Nitroanisole Genes associated with Computational Drug Signature 2-Nitroanisole, curated by the Drug Signature Dat (more detail) 7 25990557 Homo sapiens
TAX015373
GO:0004767 molecular function sphingomyelin phosphodiesterase activity Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+). (more detail) 7 NA Homo sapiens
TAX016065
GO:0006001 biological process fructose catabolic process The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2 (more detail) 5 NA Homo sapiens
MOX007070
Genes associated with Computational Drug Signature Arofyllin Genes associated with Computational Drug Signature Arofyllin, curated by the Drug Signature Database (more detail) 5 25990557 Homo sapiens
MEX000163
Genes associated with Approved Drug hydroxyzine Genes associated with Approved Drug hydroxyzine, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
TAX016548
GO:0006710 biological process androgen catabolic process The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones th (more detail) 5 NA Homo sapiens
POX000471
PathwayGeneSet, Reactome Genes associated with PathwayGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 5 NA Homo sapiens
WAG000543
Xanthine formation (more detail) 5 NA Homo sapiens
WAG000054
Beta oxidation of octanoyl CoA to hexanoyl CoA (more detail) 5 NA Homo sapiens
WIG001395
Doxepin Pathway, Pharmacokinetics Stylized liver cell showing candidate genes involved in the metabolism of the tricyclic doxepin. (more detail) 5 NA Homo sapiens
MOX002968
Genes associated with Computational Drug Signature Eupatorin Genes associated with Computational Drug Signature Eupatorin, curated by the Drug Signature Database (more detail) 5 25990557 Homo sapiens
TAX016750
GO:0007039 biological process protein catabolic process in the vacuole The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually (more detail) 5 NA Homo sapiens
TAX018131
GO:0010815 biological process bradykinin catabolic process The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin. (more detail) 5 NA Homo sapiens
TAX015069
GO:0004340 molecular function glucokinase activity Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate. (more detail) 5 NA Homo sapiens
MOX015688
Genes associated with Computational Drug Signature UK 356618 Genes associated with Computational Drug Signature UK-356618, curated by the Drug Signature Database (more detail) 5 25990557 Homo sapiens
MOX013938
Genes associated with Computational Drug Signature n pla Genes associated with Computational Drug Signature n-pla, curated by the Drug Signature Database (DS (more detail) 5 25990557 Homo sapiens
TAX013433
GO:0000467 biological process exonucleolytic trimming to generate mature 3' end of 5.8S rRNA from tricistronic rRNA transcript (SSU rRNA, 5.8S rRNA, LSU rRNA) Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecul (more detail) 5 NA Homo sapiens
TAX016390
GO:0006522 biological process alanine metabolic process The chemical reactions and pathways involving alanine, 2-aminopropanoic acid. (more detail) 5 NA Homo sapiens
TAX016419
GO:0006552 biological process leucine catabolic process The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic (more detail) 5 NA Homo sapiens
PEX000338
Aminotran 1 2: Aminotransferase class I and II (more detail) 5 NA Homo sapiens
PEX002447
ERAP1 C: ERAP1 like C terminal domain This large domain is composed of 16 alpha helices organized as 8 HEAT-like repeats. This domain for (more detail) 5 NA Homo sapiens
MOX003551
Genes associated with Computational Drug Signature 2 oxo clopidogrel Genes associated with Computational Drug Signature 2-oxo-clopidogrel, curated by the Drug Signature (more detail) 5 25990557 Homo sapiens
MOX003206
Genes associated with Computational Drug Signature Avasimibe Genes associated with Computational Drug Signature Avasimibe, curated by the Drug Signature Database (more detail) 5 25990557 Homo sapiens
TAX013529
GO:0000835 cellular component ER ubiquitin ligase complex A ubiquitin ligase complex found in the ER. (more detail) 5 NA Homo sapiens
TAX014813
GO:0003847 molecular function 1 alkyl 2 acetylglycerophosphocholine esterase activity Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3 (more detail) 5 NA Homo sapiens
TAX016107
GO:0006064 biological process glucuronate catabolic process The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of (more detail) 5 NA Homo sapiens
PEX000357
F box like: F box like This is an F-box-like family. (more detail) 5 NA Homo sapiens
MOX016195
Genes associated with Computational Drug Signature Ticrynafen Genes associated with Computational Drug Signature Ticrynafen, curated by the Drug Signature Databas (more detail) 5 25990557 Homo sapiens
MOX014890
Genes associated with Computational Drug Signature RS 130830 Genes associated with Computational Drug Signature RS-130830, curated by the Drug Signature Database (more detail) 5 25990557 Homo sapiens
POX000463
PathwayGeneSet, Reactome Genes associated with PathwayGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 5 NA Homo sapiens
WAG001380
mitochondrial fatty acid beta oxidation of unsaturated fatty acids (more detail) 5 NA Homo sapiens
MEX000223
Genes associated with Approved Drug midodrine Genes associated with Approved Drug midodrine, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX001033
Genes associated with Approved Drug aztreonam Genes associated with Approved Drug aztreonam, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX000865
Genes associated with Approved Drug azithromycin Genes associated with Approved Drug azithromycin, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
WAG000669
Beta oxidation of decanoyl CoA to octanoyl CoA CoA (more detail) 5 NA Homo sapiens
WAG000887
Isoleucine catabolism (more detail) 5 NA Homo sapiens
WAG000053
Beta oxidation of lauroyl CoA to decanoyl CoA CoA (more detail) 5 NA Homo sapiens
MOX001563
Genes associated with Computational Drug Signature Rhc 80267 Genes associated with Computational Drug Signature Rhc 80267, curated by the Drug Signature Database (more detail) 5 25990557 Homo sapiens
MOX001894
Genes associated with Computational Drug Signature desethylamodiaquine Genes associated with Computational Drug Signature desethylamodiaquine, curated by the Drug Signatur (more detail) 5 25990557 Homo sapiens
TAX016391
GO:0006524 biological process alanine catabolic process The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid. (more detail) 5 NA Homo sapiens
TAX013530
GO:0000836 cellular component Hrd1p ubiquitin ligase complex A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membran (more detail) 5 NA Homo sapiens
TAX015113
GO:0004396 molecular function hexokinase activity Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate. (more detail) 5 NA Homo sapiens
WAG000869
Beta oxidation of hexanoyl CoA to butanoyl CoA (more detail) 5 NA Homo sapiens
MEX001021
Genes associated with Approved Drug ceftriaxone Genes associated with Approved Drug ceftriaxone, curated by the Drug Signature Database (DSigDB). (more detail) 5 25990557 Homo sapiens
MEX003145
Genes associated with Perturbagen Signature etamsylate Genes associated with Perturbagen Signature etamsylate, curated by the Drug Signature Database (DSig (more detail) 5 25990557 Homo sapiens
PEX002543
Glyco hydro 18: Glycosyl hydrolases family 18 (more detail) 5 NA Homo sapiens
WIG001427
Catabolic Pathways for Methionine, Isoleucine, Threonine and Valine Catabolic Pathways for Methionine, Isoleucine, Threonine and Valine (more detail) 5 NA Homo sapiens
TAX013427
GO:0000459 biological process exonucleolytic trimming involved in rRNA processing Exonucleolytic digestion of a pre-rRNA molecule in the process to generate a mature rRNA molecule. (more detail) 5 NA Homo sapiens
TAX028846
GO:0070290 molecular function N acylphosphatidylethanolamine specific phospholipase D activity Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to genera (more detail) 5 NA Homo sapiens
TAX019770
GO:0019640 biological process glucuronate catabolic process to xylulose 5 phosphate The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, (more detail) 5 NA Homo sapiens
TAX019620
GO:0019158 molecular function mannokinase activity Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate. (more detail) 5 NA Homo sapiens
TAX028513
GO:0061624 biological process fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde 3 phosphate The chemical reactions and pathways resulting in the breakdown of fructose that results in the forma (more detail) 5 NA Homo sapiens
IEI013432
Protein protein interactors of human gene TBC1D9 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBC1D9 (SwissProt ID (more detail) 5 17535438 Homo sapiens
TAX031545
GO:0103068 molecular function leukotriene C4 gamma glutamyl transferase activity Catalysis of the reaction: leukotriene C4 + a standard alpha amino acid = leukotriene D4 + an (gamma (more detail) 5 NA Homo sapiens
TAX021794
GO:0032803 biological process regulation of low density lipoprotein particle receptor catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resu (more detail) 5 NA Homo sapiens
TAX022275
GO:0034031 biological process ribonucleoside bisphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a c (more detail) 5 NA Homo sapiens
TAX020404
GO:0030242 biological process autophagy of peroxisome The process in which peroxisomes are delivered to the vacuole and degraded in response to changing n (more detail) 5 NA Homo sapiens
TAX034331
GO:1990726 cellular component Lsm1 7 Pat1 complex A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, (more detail) 5 NA Homo sapiens
TAX032143
GO:1901523 biological process icosanoid catabolic process The chemical reactions and pathways resulting in the breakdown of icosanoid. (more detail) 5 NA Homo sapiens
IEI008395
Protein protein interactors of human gene MVB12B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene MVB12B (SwissProt ID (more detail) 5 17535438 Homo sapiens
TAX030149
GO:0075071 biological process autophagy involved in symbiotic interaction The process in which cells digest parts of their own cytoplasm during a symbiotic interaction; allow (more detail) 5 NA Homo sapiens
TAX017492
GO:0009080 biological process pyruvate family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruv (more detail) 5 NA Homo sapiens
TAX022278
GO:0034034 biological process purine nucleoside bisphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, (more detail) 5 NA Homo sapiens
TAX032024
GO:1901159 biological process xylulose 5 phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate. (more detail) 5 NA Homo sapiens
TAX023030
GO:0035694 biological process mitochondrial protein catabolic process The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This proc (more detail) 5 NA Homo sapiens
TAX023210
GO:0036021 cellular component endolysosome lumen The volume enclosed by the membrane of an endolysosome. An endolysosome is a transient hybrid organe (more detail) 5 NA Homo sapiens
TAX018207
GO:0010901 biological process regulation of very low density lipoprotein particle remodeling Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle re (more detail) 5 NA Homo sapiens
TAX022252
GO:0033869 biological process nucleoside bisphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compo (more detail) 5 NA Homo sapiens
TAX019727
GO:0019441 biological process tryptophan catabolic process to kynurenine The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, i (more detail) 5 NA Homo sapiens
TAX034407
GO:1990948 molecular function ubiquitin ligase inhibitor activity Stops, prevents or reduces the activity of a ubiquitin ligase. (more detail) 5 NA Homo sapiens
TAX028565
GO:0061734 biological process parkin mediated stimulation of mitophagy in response to mitochondrial depolarization A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarizatio (more detail) 5 NA Homo sapiens
TAX022438
GO:0034363 cellular component intermediate density lipoprotein particle A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a d (more detail) 5 NA Homo sapiens
TAX024373
GO:0043456 biological process regulation of pentose phosphate shunt Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process (more detail) 5 NA Homo sapiens
TAX033125
GO:1903772 biological process regulation of viral budding via host ESCRT complex Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex. (more detail) 5 NA Homo sapiens
IEI011419
Protein protein interactors of human gene RNF186 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF186 (SwissProt ID (more detail) 5 17535438 Homo sapiens
TAX022124
GO:0033503 cellular component HULC complex A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin (more detail) 5 NA Homo sapiens
TAX023019
GO:0035671 molecular function enone reductase activity Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+. (more detail) 5 NA Homo sapiens
TAX029324
GO:0071218 biological process cellular response to misfolded protein Any process that results in a change in state or activity of a cell (in terms of movement, secretion (more detail) 5 NA Homo sapiens
TAX017435
GO:0008865 molecular function fructokinase activity Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate. (more detail) 5 NA Homo sapiens
TAX026842
GO:0051167 biological process xylulose 5 phosphate metabolic process The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose (more detail) 5 NA Homo sapiens
IEI005563
Protein protein interactors of human gene GSTM2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GSTM2 (SwissProt ID= (more detail) 5 17535438 Homo sapiens
TAX030148
GO:0075044 biological process autophagy of host cells involved in interaction with symbiont The process in which the host cells digest parts of their own cytoplasm during interaction with its (more detail) 5 NA Homo sapiens
TAX029267
GO:0071038 biological process nuclear polyadenylation dependent tRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an ab (more detail) 5 NA Homo sapiens
TAX025425
GO:0046069 biological process cGMP catabolic process The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosph (more detail) 5 NA Homo sapiens
TAX023819
GO:0042406 cellular component extrinsic component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of gene products and protein complexe (more detail) 5 NA Homo sapiens
TAX022923
GO:0035529 molecular function NADH pyrophosphatase activity Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+. (more detail) 5 NA Homo sapiens
TAX017608
GO:0009217 biological process purine deoxyribonucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphos (more detail) 5 NA Homo sapiens
TAX024003
GO:0042760 biological process very long chain fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of a fatty acid which has a chain len (more detail) 5 NA Homo sapiens
TAX017491
GO:0009078 biological process pyruvate family amino acid metabolic process The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesi (more detail) 5 NA Homo sapiens
IEI005618
Protein protein interactors of human gene GUF1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GUF1 (SwissProt ID=Q (more detail) 5 17535438 Homo sapiens
TAX031534
GO:0102953 molecular function hypoglycin A gamma glutamyl transpeptidase activity Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B (more detail) 5 NA Homo sapiens
TAX022576
GO:0034638 biological process phosphatidylcholine catabolic process The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a cla (more detail) 5 NA Homo sapiens
TAX032817
GO:1903147 biological process negative regulation of autophagy of mitochondrion Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradati (more detail) 8 NA Homo sapiens
TAX018204
GO:0010898 biological process positive regulation of triglyceride catabolic process Any process that increases the frequency, rate, or extent of the chemical reactions and pathways res (more detail) 8 NA Homo sapiens
IEI000928
Protein protein interactors of human gene ARRDC4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ARRDC4 (SwissProt ID (more detail) 8 17535438 Homo sapiens
IEI003631
Protein protein interactors of human gene DNAAF4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DNAAF4 (SwissProt ID (more detail) 8 17535438 Homo sapiens
TAX031122
GO:0098779 biological process positive regulation of mitophagy in response to mitochondrial depolarization Any process that activates or increases the frequency, rate or extent of mitophagy in response to mi (more detail) 8 NA Homo sapiens
IEI013377
Protein protein interactors of human gene TAOK3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TAOK3 (SwissProt ID= (more detail) 8 17535438 Homo sapiens
TAX025809
GO:0046920 molecular function alpha (1 >3) fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to fo (more detail) 8 NA Homo sapiens
TAX022456
GO:0034382 biological process chylomicron remnant clearance The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytos (more detail) 8 NA Homo sapiens
TAX029695
GO:0071830 biological process triglyceride rich lipoprotein particle clearance The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor (more detail) 8 NA Homo sapiens
TAX032146
GO:1901526 biological process positive regulation of mitophagy Any process that activates or increases the frequency, rate or extent of mitophagy. (more detail) 8 NA Homo sapiens
MOX015025
Genes associated with Computational Drug Signature SC 44463 Genes associated with Computational Drug Signature SC-44463, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
MOX001561
Genes associated with Computational Drug Signature aniracetam Genes associated with Computational Drug Signature aniracetam, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
MOX004333
Genes associated with Computational Drug Signature methomyl Genes associated with Computational Drug Signature methomyl, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
MOX004546
Genes associated with Computational Drug Signature piribedil Genes associated with Computational Drug Signature piribedil, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
WIG001815
Catabolic Pathway for Arginine,Histidine,Glutamate,Glutamine and Proline Catabolic Pathway for Arginine,Histidine,Glutamate,Glutamine and Proline (more detail) 8 NA Homo sapiens
WAG000657
apoptotic dna fragmentation and tissue homeostasis Apoptotic cell death can be triggered by many different cellular stimuli, resulting in activation of (more detail) 8 NA Homo sapiens
MEX000130
Genes associated with Approved Drug fluconazole Genes associated with Approved Drug fluconazole, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
TAX015876
GO:0005688 cellular component U6 snRNP A ribonucleoprotein complex that contains small nuclear RNA U6. (more detail) 8 NA Homo sapiens
MOX011985
Genes associated with Computational Drug Signature ciprofloxacin Genes associated with Computational Drug Signature ciprofloxacin, curated by the Drug Signature Data (more detail) 8 25990557 Homo sapiens
WIG001326
Warfarin Pathway, Pharmacokinetics Representation of the candidate genes involved in transport, metabolism and clearance of warfarin. (more detail) 8 NA Homo sapiens
MOX004918
Genes associated with Computational Drug Signature fluconazole Genes associated with Computational Drug Signature fluconazole, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
MOX013797
Genes associated with Computational Drug Signature MRS 1220 Genes associated with Computational Drug Signature MRS 1220, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
TAX016753
GO:0007042 biological process lysosomal lumen acidification Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydroge (more detail) 8 NA Homo sapiens
MOX012613
Genes associated with Computational Drug Signature Etidronic acid Genes associated with Computational Drug Signature Etidronic acid, curated by the Drug Signature Dat (more detail) 8 25990557 Homo sapiens
MOX004664
Genes associated with Computational Drug Signature Etidronic acid Genes associated with Computational Drug Signature Etidronic acid, curated by the Drug Signature Dat (more detail) 8 25990557 Homo sapiens
MEX001184
Genes associated with Approved Drug minocycline Genes associated with Approved Drug minocycline, curated by the Drug Signature Database (DSigDB). (more detail) 8 25990557 Homo sapiens
MOX007479
Genes associated with Computational Drug Signature Capsaicin Genes associated with Computational Drug Signature Capsaicin, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
MOX002814
Genes associated with Computational Drug Signature olomoucine Genes associated with Computational Drug Signature olomoucine, curated by the Drug Signature Databas (more detail) 8 25990557 Homo sapiens
MOX006316
Genes associated with Computational Drug Signature 693228 63 6 Genes associated with Computational Drug Signature 693228-63-6, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
WIG001338
Gefitinib Pathway, Pharmacokinetics Representation of the candidate genes involved in the transportation and metabolism of gefitinib. (more detail) 8 NA Homo sapiens
MOX015947
Genes associated with Computational Drug Signature ZILEUTON Genes associated with Computational Drug Signature ZILEUTON, curated by the Drug Signature Database (more detail) 8 25990557 Homo sapiens
MOX004787
Genes associated with Computational Drug Signature TROLEANDOMYCIN Genes associated with Computational Drug Signature TROLEANDOMYCIN, curated by the Drug Signature Dat (more detail) 8 25990557 Homo sapiens
MOX003906
Genes associated with Computational Drug Signature cyproterone Genes associated with Computational Drug Signature cyproterone, curated by the Drug Signature Databa (more detail) 8 25990557 Homo sapiens
WIG001377
Caffeine Pathway, Pharmacokinetics Stylized liver cell showing candidate genes involved in the metabolism of caffeine. (more detail) 8 NA Homo sapiens
MOX014687
Genes associated with Computational Drug Signature pyridostigmine Genes associated with Computational Drug Signature pyridostigmine, curated by the Drug Signature Dat (more detail) 6 25990557 Homo sapiens
MOX016442
Genes associated with Computational Drug Signature Cefobid Genes associated with Computational Drug Signature Cefobid, curated by the Drug Signature Database ( (more detail) 6 25990557 Homo sapiens
WIG001351
Fluoxetine Pathway, Pharmacokinetics Representation of the candidate genes involved in the metabolism of fluoxetine. (more detail) 6 NA Homo sapiens
MOX013425
Genes associated with Computational Drug Signature Leuprorelin Genes associated with Computational Drug Signature Leuprorelin, curated by the Drug Signature Databa (more detail) 6 25990557 Homo sapiens
MOX000611
Genes associated with Computational Drug Signature Dimemorfan Genes associated with Computational Drug Signature Dimemorfan, curated by the Drug Signature Databas (more detail) 6 25990557 Homo sapiens
MOX001346
Genes associated with Computational Drug Signature salicylamide Genes associated with Computational Drug Signature salicylamide, curated by the Drug Signature Datab (more detail) 6 25990557 Homo sapiens
WAG001153
Vitamins (more detail) 6 NA Homo sapiens
MOX015576
Genes associated with Computational Drug Signature Torasemide Genes associated with Computational Drug Signature Torasemide, curated by the Drug Signature Databas (more detail) 6 25990557 Homo sapiens
TAX016433
GO:0006566 biological process threonine metabolic process The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, un (more detail) 6 NA Homo sapiens
TAX015046
GO:0004308 molecular function exo alpha sialidase activity Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of ter (more detail) 6 NA Homo sapiens
MOX001987
Genes associated with Computational Drug Signature AC1L1DD3 Genes associated with Computational Drug Signature AC1L1DD3, curated by the Drug Signature Database (more detail) 6 25990557 Homo sapiens
MOX017776
Genes associated with Computational Drug Signature SULFADOXINE Genes associated with Computational Drug Signature SULFADOXINE, curated by the Drug Signature Databa (more detail) 6 25990557 Homo sapiens
MOX018003
Genes associated with Computational Drug Signature Clorgiline Genes associated with Computational Drug Signature Clorgiline, curated by the Drug Signature Databas (more detail) 6 25990557 Homo sapiens
MOX012870
Genes associated with Computational Drug Signature glycine Genes associated with Computational Drug Signature glycine, curated by the Drug Signature Database ( (more detail) 6 25990557 Homo sapiens
TAX015120
GO:0004415 molecular function hyalurononglucosaminidase activity Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-gluc (more detail) 6 NA Homo sapiens
MOX000522
Genes associated with Computational Drug Signature Bufuralol Genes associated with Computational Drug Signature Bufuralol, curated by the Drug Signature Database (more detail) 6 25990557 Homo sapiens
MOX000860
Genes associated with Computational Drug Signature Isomalathion Genes associated with Computational Drug Signature Isomalathion, curated by the Drug Signature Datab (more detail) 6 25990557 Homo sapiens
MEX000580
Genes associated with Approved Drug torasemide Genes associated with Approved Drug torasemide, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
WIG001385
Sorafenib Pharmacokinetics Sorafenib Pharmacokinetics (more detail) 6 NA Homo sapiens
FEX001280
Leukemia Wang03 06genes Table 1. Up-Regulated Genes in NB4 cells (more detail) 6 12890387 Homo sapiens
MEX001055
Genes associated with Approved Drug dantrolene Genes associated with Approved Drug dantrolene, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
MEX000835
Genes associated with Approved Drug metyrosine Genes associated with Approved Drug metyrosine, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
WIG001382
Nevirapine Pathway, Pharmacokinetics Representation of candidate genes involved in biotransformation of nevirapine and its mechanism of a (more detail) 6 NA Homo sapiens
MEX000508
Genes associated with Approved Drug tranylcypromine Genes associated with Approved Drug tranylcypromine, curated by the Drug Signature Database (DSigDB) (more detail) 6 25990557 Homo sapiens
MOX013781
Genes associated with Computational Drug Signature montelukast Genes associated with Computational Drug Signature montelukast, curated by the Drug Signature Databa (more detail) 6 25990557 Homo sapiens
MEX000839
Genes associated with Approved Drug linezolid Genes associated with Approved Drug linezolid, curated by the Drug Signature Database (DSigDB). (more detail) 6 25990557 Homo sapiens
PEX001552
zf UBP: Zn finger in ubiquitin hydrolases and other protein (more detail) 6 NA Homo sapiens
MOX007182
Genes associated with Computational Drug Signature batimastat Genes associated with Computational Drug Signature batimastat, curated by the Drug Signature Databas (more detail) 6 25990557 Homo sapiens
TAX014877
GO:0003958 molecular function NADPH hemoprotein reductase activity Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein. (more detail) 6 NA Homo sapiens
MOX013059
Genes associated with Computational Drug Signature hydroxyzine Genes associated with Computational Drug Signature hydroxyzine, curated by the Drug Signature Databa (more detail) 6 25990557 Homo sapiens
PEX000970
His Phos 1: Histidine phosphatase superfamily (branch 1) The histidine phosphatase superfamily is so named because catalysis centres on a conserved His resid (more detail) 6 NA Homo sapiens
TAX027581
GO:0055105 molecular function ubiquitin protein transferase inhibitor activity Stops, prevents or reduces the activity of a ubiquitin-protein transferase. (more detail) 6 NA Homo sapiens
TAX027751
GO:0060228 molecular function phosphatidylcholine sterol O acyltransferase activator activity Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts chol (more detail) 6 NA Homo sapiens
IEI014623
Protein protein interactors of human gene UBR3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene UBR3 (SwissProt ID=Q (more detail) 6 17535438 Homo sapiens
TAX032278
GO:1901857 biological process positive regulation of cellular respiration Any process that activates or increases the frequency, rate or extent of cellular respiration. (more detail) 6 NA Homo sapiens
TAX019324
GO:0016997 molecular function alpha sialidase activity Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids. (more detail) 6 NA Homo sapiens
IEI012618
Protein protein interactors of human gene SMG8 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SMG8 (SwissProt ID=Q (more detail) 6 17535438 Homo sapiens
IEI005541
Protein protein interactors of human gene GSDMA from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene GSDMA (SwissProt ID= (more detail) 6 17535438 Homo sapiens
IEI009516
Protein protein interactors of human gene PARS2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PARS2 (SwissProt ID= (more detail) 6 17535438 Homo sapiens
TAX033171
GO:1903862 biological process positive regulation of oxidative phosphorylation Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation. (more detail) 6 NA Homo sapiens
IEI006720
Protein protein interactors of human gene KCNN4 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene KCNN4 (SwissProt ID= (more detail) 6 17535438 Homo sapiens
IEI012056
Protein protein interactors of human gene SESN1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene SESN1 (SwissProt ID= (more detail) 6 17535438 Homo sapiens
TAX024152
GO:0043096 biological process purine nucleobase salvage Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring co (more detail) 6 NA Homo sapiens
IEI001309
Protein protein interactors of human gene BECN2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene BECN2 (SwissProt ID= (more detail) 6 17535438 Homo sapiens
IEI009350
Protein protein interactors of human gene OSBPL5 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene OSBPL5 (SwissProt ID (more detail) 6 17535438 Homo sapiens
TAX032145
GO:1901525 biological process negative regulation of mitophagy Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy. (more detail) 6 NA Homo sapiens
TAX029091
GO:0070728 molecular function leucine binding Interacting selectively and non-covalently with 2-amino-4-methylpentanoic acid. (more detail) 6 NA Homo sapiens
TAX030652
GO:0097052 biological process L kynurenine metabolic process The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynur (more detail) 6 NA Homo sapiens
TAX032881
GO:1903301 biological process positive regulation of hexokinase activity Any process that activates or increases the frequency, rate or extent of hexokinase activity. (more detail) 6 NA Homo sapiens
TAX018864
GO:0016098 biological process monoterpenoid metabolic process The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skele (more detail) 6 NA Homo sapiens
IEI003500
Protein protein interactors of human gene DGAT2L7P from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene DGAT2L7P (SwissProt (more detail) 6 17535438 Homo sapiens
TAX018801
GO:0015942 biological process formate metabolic process The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- der (more detail) 6 NA Homo sapiens
TAX028569
GO:0061739 biological process protein lipidation involved in autophagosome assembly The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the A (more detail) 4 NA Homo sapiens
TAX017940
GO:0010499 biological process proteasomal ubiquitin independent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis (more detail) 4 NA Homo sapiens
TAX024048
GO:0042851 biological process L alanine metabolic process The chemical reactions and pathways involving L-alanine, the L-enantiomer of 2-aminopropanoic acid, (more detail) 4 NA Homo sapiens
TAX019033
GO:0016453 molecular function C acetyltransferase activity Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule. (more detail) 4 NA Homo sapiens
TAX019734
GO:0019477 biological process L lysine catabolic process The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)- (more detail) 4 NA Homo sapiens
TAX025566
GO:0046440 biological process L lysine metabolic process The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic (more detail) 4 NA Homo sapiens
TAX033933
GO:1905448 biological process positive regulation of mitochondrial ATP synthesis coupled electron transport Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis (more detail) 4 NA Homo sapiens
IEI010182
Protein protein interactors of human gene POFUT2 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene POFUT2 (SwissProt ID (more detail) 4 17535438 Homo sapiens
IEI014798
Protein protein interactors of human gene USP51 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene USP51 (SwissProt ID= (more detail) 4 17535438 Homo sapiens
TAX018805
GO:0015961 biological process diadenosine polyphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a deriv (more detail) 4 NA Homo sapiens
TAX019731
GO:0019470 biological process 4 hydroxyproline catabolic process The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a deriv (more detail) 4 NA Homo sapiens
TAX019743
GO:0019518 biological process L threonine catabolic process to glycine The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2 (more detail) 4 NA Homo sapiens
TAX018867
GO:0016103 biological process diterpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids (more detail) 4 NA Homo sapiens
TAX019559
GO:0018916 biological process nitrobenzene metabolic process The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene wi (more detail) 4 NA Homo sapiens
TAX027447
GO:0052794 molecular function exo alpha (2 >3) sialidase activity Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in subst (more detail) 4 NA Homo sapiens
TAX025627
GO:0046538 molecular function 2,3 bisphosphoglycerate dependent phosphoglycerate mutase activity Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the (more detail) 4 NA Homo sapiens
TAX032304
GO:1901909 biological process diadenosine hexaphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate. (more detail) 4 NA Homo sapiens
TAX030087
GO:0072606 biological process interleukin 8 secretion The regulated release of interleukin-8 from a cell. (more detail) 4 NA Homo sapiens
TAX022397
GO:0034271 cellular component phosphatidylinositol 3 kinase complex, class III, type I A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, t (more detail) 4 NA Homo sapiens
TAX022431
GO:0034354 biological process 'de novo' NAD biosynthetic process from tryptophan The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (more detail) 4 NA Homo sapiens
TAX017575
GO:0009181 biological process purine ribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, (more detail) 4 NA Homo sapiens
TAX017404
GO:0008745 molecular function N acetylmuramoyl L alanine amidase activity Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues (more detail) 4 NA Homo sapiens
TAX019733
GO:0019474 biological process L lysine catabolic process to acetyl CoA The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, inc (more detail) 4 NA Homo sapiens
TAX024309
GO:0043328 biological process protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway The process of directing proteins towards the vacuole that contributes to protein catabolism via the (more detail) 4 NA Homo sapiens
TAX026402
GO:0050051 molecular function leukotriene B4 20 monooxygenase activity Catalysis of the reaction: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADP (more detail) 4 NA Homo sapiens
TAX025482
GO:0046167 biological process glycerol 3 phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric (more detail) 4 NA Homo sapiens
TAX032302
GO:1901907 biological process diadenosine pentaphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate. (more detail) 4 NA Homo sapiens
IEI013405
Protein protein interactors of human gene TBC1D10B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene TBC1D10B (SwissProt (more detail) 4 17535438 Homo sapiens
IEI007529
Protein protein interactors of human gene LYPLAL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene LYPLAL1 (SwissProt I (more detail) 4 17535438 Homo sapiens
TAX022588
GO:0034653 biological process retinoic acid catabolic process The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three co (more detail) 4 NA Homo sapiens
TAX029268
GO:0071042 biological process nuclear polyadenylation dependent mRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a mes (more detail) 4 NA Homo sapiens
TAX029273
GO:0071047 biological process polyadenylation dependent mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, i (more detail) 4 NA Homo sapiens
TAX017679
GO:0009403 biological process toxin biosynthetic process The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typic (more detail) 4 NA Homo sapiens
TAX024049
GO:0042853 biological process L alanine catabolic process The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-a (more detail) 4 NA Homo sapiens
TAX024470
GO:0043606 biological process formamide metabolic process The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from fo (more detail) 4 NA Homo sapiens
TAX019759
GO:0019556 biological process histidine catabolic process to glutamate and formamide The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, in (more detail) 4 NA Homo sapiens
TAX019760
GO:0019557 biological process histidine catabolic process to glutamate and formate The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, in (more detail) 4 NA Homo sapiens
TAX025447
GO:0046102 biological process inosine metabolic process The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found fre (more detail) 4 NA Homo sapiens
TAX025493
GO:0046208 biological process spermine catabolic process The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found (more detail) 4 NA Homo sapiens
TAX027141
GO:0051697 biological process protein delipidation The breakage of covalent bonds to detach lipid groups from a protein. (more detail) 4 NA Homo sapiens
TAX027449
GO:0052796 molecular function exo alpha (2 >8) sialidase activity Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in subst (more detail) 4 NA Homo sapiens
TAX032301
GO:1901906 biological process diadenosine pentaphosphate metabolic process The chemical reactions and pathways involving diadenosine pentaphosphate. (more detail) 4 NA Homo sapiens
TAX032305
GO:1901910 biological process adenosine 5' (hexahydrogen pentaphosphate) metabolic process The chemical reactions and pathways involving adenosine 5'-(hexahydrogen pentaphosphate). (more detail) 4 NA Homo sapiens
WEX000104
Tryptophan & Kynurenine Metabolism The genes related to tryptophan & kynurenine metabolism (metabolism) in tumor, immune, stroma using (more detail) 4 NA Homo sapiens
IEI006570
Protein protein interactors of human gene ITPRIPL1 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene ITPRIPL1 (SwissProt (more detail) 4 17535438 Homo sapiens
TAX023255
GO:0036102 biological process leukotriene B4 metabolic process The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,1 (more detail) 4 NA Homo sapiens
TAX029269
GO:0071043 biological process CUT metabolic process The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcr (more detail) 4 NA Homo sapiens
TAX017682
GO:0009407 biological process toxin catabolic process The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typic (more detail) 4 NA Homo sapiens
TAX019664
GO:0019262 biological process N acetylneuraminate catabolic process The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of (more detail) 4 NA Homo sapiens
TAX032015
GO:1901097 biological process negative regulation of autophagosome maturation Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturatio (more detail) 4 NA Homo sapiens
IEI015024
Protein protein interactors of human gene WDR76 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene WDR76 (SwissProt ID= (more detail) 4 17535438 Homo sapiens
IEI010020
Protein protein interactors of human gene PLAAT3 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene PLAAT3 (SwissProt ID (more detail) 4 17535438 Homo sapiens
IEI011086
Protein protein interactors of human gene RBM38 from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RBM38 (SwissProt ID= (more detail) 4 17535438 Homo sapiens
IEI011380
Protein protein interactors of human gene RNF113B from the Interologous Interaction Database ver 2.9 This PAG records all the protein-protein interaction partners of the human gene RNF113B (SwissProt I (more detail) 4 17535438 Homo sapiens
TAX022668
GO:0034875 molecular function caffeine oxidase activity Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O. (more detail) 4 NA Homo sapiens
TAX029526
GO:0071543 biological process diphosphoinositol polyphosphate metabolic process The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohe (more detail) 4 NA Homo sapiens
TAX031129
GO:0098792 biological process xenophagy The macroautophagy process in which a region of cytoplasm containing an intracellular pathogen or so (more detail) 4 NA Homo sapiens
TAX029265
GO:0071034 biological process CUT catabolic process The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs (more detail) 4 NA Homo sapiens
TAX017535
GO:0009137 biological process purine nucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a c (more detail) 4 NA Homo sapiens
TAX024156
GO:0043103 biological process hypoxanthine salvage Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo sy (more detail) 4 NA Homo sapiens
TAX025829
GO:0046952 biological process ketone body catabolic process The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the thre (more detail) 4 NA Homo sapiens
TAX027448
GO:0052795 molecular function exo alpha (2 >6) sialidase activity Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in subst (more detail) 4 NA Homo sapiens
TAX033371
GO:1904288 molecular function BAT3 complex binding Interacting selectively and non-covalently with a BAT3 complex. (more detail) 4 NA Homo sapiens
TAX032306
GO:1901911 biological process adenosine 5' (hexahydrogen pentaphosphate) catabolic process The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaph (more detail) 4 NA Homo sapiens
TAX023254
GO:0036101 biological process leukotriene B4 catabolic process The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene comp (more detail) 4 NA Homo sapiens
TAX020344
GO:0030167 biological process proteoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in (more detail) 4 NA Homo sapiens
TAX022398
GO:0034272 cellular component phosphatidylinositol 3 kinase complex, class III, type II A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) (more detail) 4 NA Homo sapiens
TAX023253
GO:0036100 biological process leukotriene catabolic process The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically (more detail) 4 NA Homo sapiens
TAX022482
GO:0034431 molecular function bis(5' adenosyl) hexaphosphatase activity Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphos (more detail) 4 NA Homo sapiens
TAX024177
GO:0043137 biological process DNA replication, removal of RNA primer Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of th (more detail) 4 NA Homo sapiens
TAX022218
GO:0033695 molecular function oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or elec (more detail) 4 NA Homo sapiens
TAX025779
GO:0046874 biological process quinolinate metabolic process The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known (more detail) 4 NA Homo sapiens
TAX032303
GO:1901908 biological process diadenosine hexaphosphate metabolic process The chemical reactions and pathways involving diadenosine hexaphosphate. (more detail) 4 NA Homo sapiens
TAX022483
GO:0034432 molecular function bis(5' adenosyl) pentaphosphatase activity Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetrapho (more detail) 4 NA Homo sapiens
MOX009284
Genes associated with Computational Drug Signature CHEMBL263501 Genes associated with Computational Drug Signature CHEMBL263501, curated by the Drug Signature Datab (more detail) 4 25990557 Homo sapiens
MOX013346
Genes associated with Computational Drug Signature L 873724 Genes associated with Computational Drug Signature L-873724, curated by the Drug Signature Database (more detail) 4 25990557 Homo sapiens
TAX016440
GO:0006574 biological process valine catabolic process The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic a (more detail) 4 NA Homo sapiens
MOX007052
Genes associated with Computational Drug Signature Apremilast Genes associated with Computational Drug Signature Apremilast, curated by the Drug Signature Databas (more detail) 4 25990557 Homo sapiens
MOX007186
Genes associated with Computational Drug Signature BB 1101 Genes associated with Computational Drug Signature BB-1101, curated by the Drug Signature Database ( (more detail) 4 25990557 Homo sapiens
PEX000531
Hexokinase 2: Hexokinase Hexokinase (EC:2.7.1.1) contains two structurally similar domains represented by this family and Pfa (more detail) 4 NA Homo sapiens
POX000433
IsozymeGeneSet, KEGG Enzyme Genes associated with IsozymeGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
PEX001701
Cullin Nedd8: Cullin protein neddylation domain This is the neddylation site of cullin proteins which are a family of structurally related proteins (more detail) 4 NA Homo sapiens
PEX002118
Thiolase C: Thiolase, C terminal domain Thiolase is reported to be structurally related to beta-ketoacyl synthase (Pfam:PF00109), and also (more detail) 4 NA Homo sapiens
MOX011759
Genes associated with Computational Drug Signature CHEMBL77258 Genes associated with Computational Drug Signature CHEMBL77258, curated by the Drug Signature Databa (more detail) 4 25990557 Homo sapiens
POX000454
IsozymeGeneSet, KEGG Enzyme Genes associated with IsozymeGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
MOX014149
Genes associated with Computational Drug Signature NSC119911 Genes associated with Computational Drug Signature NSC119911, curated by the Drug Signature Database (more detail) 4 25990557 Homo sapiens
POX000409
IsozymeGeneSet, KEGG Enzyme Genes associated with IsozymeGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
POX000452
IsozymeGeneSet, KEGG Enzyme Genes associated with IsozymeGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
POX000414
IsozymeGeneSet, KEGG Enzyme Genes associated with IsozymeGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
MOX003840
Genes associated with Computational Drug Signature proguanil Genes associated with Computational Drug Signature proguanil, curated by the Drug Signature Database (more detail) 4 25990557 Homo sapiens
MOX002927
Genes associated with Computational Drug Signature FORMETANATE Genes associated with Computational Drug Signature FORMETANATE, curated by the Drug Signature Databa (more detail) 4 25990557 Homo sapiens
MOX013358
Genes associated with Computational Drug Signature L NIL Genes associated with Computational Drug Signature L-NIL, curated by the Drug Signature Database (DS (more detail) 4 25990557 Homo sapiens
TAX016154
GO:0006145 biological process purine nucleobase catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two (more detail) 4 NA Homo sapiens
TAX014966
GO:0004082 molecular function bisphosphoglycerate mutase activity Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate. (more detail) 4 NA Homo sapiens
MOX015767
Genes associated with Computational Drug Signature UNII TO043KKB9C Genes associated with Computational Drug Signature UNII-TO043KKB9C, curated by the Drug Signature Da (more detail) 4 25990557 Homo sapiens
MOX014420
Genes associated with Computational Drug Signature PeramiFlu Genes associated with Computational Drug Signature PeramiFlu, curated by the Drug Signature Database (more detail) 4 25990557 Homo sapiens
WAG000088
Mitochondrial Fatty Acid Beta Oxidation (more detail) 4 NA Homo sapiens
WIG001387
Clomipramine Pathway, Pharmacokinetics Schematic representation of clomipramine metabolism in human liver. (more detail) 4 NA Homo sapiens
MEX000205
Genes associated with Approved Drug mepivacaine Genes associated with Approved Drug mepivacaine, curated by the Drug Signature Database (DSigDB). (more detail) 4 25990557 Homo sapiens
MOX013326
Genes associated with Computational Drug Signature L 006235 Genes associated with Computational Drug Signature L 006235, curated by the Drug Signature Database (more detail) 4 25990557 Homo sapiens
MOX013138
Genes associated with Computational Drug Signature indirubin 5 sulphonate Genes associated with Computational Drug Signature indirubin-5-sulphonate, curated by the Drug Signa (more detail) 4 25990557 Homo sapiens
PEX000268
Thiolase N: Thiolase, N terminal domain Thiolase is reported to be structurally related to beta-ketoacyl synthase (Pfam:PF00109), and also (more detail) 4 NA Homo sapiens
WAG000268
Proteogylcan syndecan mediated signaling events (more detail) 4 NA Homo sapiens
TAX013355
GO:0000298 molecular function endopolyphosphatase activity Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 (more detail) 4 NA Homo sapiens
WAG000305
Histidine catabolism (more detail) 4 NA Homo sapiens
WAG000079
Digestion of dietary lipid (more detail) 4 NA Homo sapiens
MOX001120
Genes associated with Computational Drug Signature FENPROPOREX Genes associated with Computational Drug Signature FENPROPOREX, curated by the Drug Signature Databa (more detail) 4 25990557 Homo sapiens
MOX001598
Genes associated with Computational Drug Signature 1,3 DINITROPYRENE Genes associated with Computational Drug Signature 1,3-DINITROPYRENE, curated by the Drug Signature (more detail) 4 25990557 Homo sapiens
MOX006356
Genes associated with Computational Drug Signature 7 nitroindazole Genes associated with Computational Drug Signature 7-nitroindazole, curated by the Drug Signature Da (more detail) 4 25990557 Homo sapiens
WAG001231
Peptidoglycan biosynthesis (more detail) 4 NA Homo sapiens
MEX001102
Genes associated with Approved Drug homatropine methylbromide Genes associated with Approved Drug homatropine methylbromide, curated by the Drug Signature Databas (more detail) 4 25990557 Homo sapiens
MOX001708
Genes associated with Computational Drug Signature CCRIS 1846 Genes associated with Computational Drug Signature CCRIS 1846, curated by the Drug Signature Databas (more detail) 4 25990557 Homo sapiens
MOX000588
Genes associated with Computational Drug Signature Carbamazepine epoxide Genes associated with Computational Drug Signature Carbamazepine epoxide, curated by the Drug Signat (more detail) 4 25990557 Homo sapiens
MOX005088
Genes associated with Computational Drug Signature xanthine Genes associated with Computational Drug Signature xanthine, curated by the Drug Signature Database (more detail) 4 25990557 Homo sapiens
MOX003190
Genes associated with Computational Drug Signature Thiacloprid Genes associated with Computational Drug Signature Thiacloprid, curated by the Drug Signature Databa (more detail) 4 25990557 Homo sapiens
MOX011409
Genes associated with Computational Drug Signature CHEMBL572982 Genes associated with Computational Drug Signature CHEMBL572982, curated by the Drug Signature Datab (more detail) 4 25990557 Homo sapiens
TAX016434
GO:0006567 biological process threonine catabolic process The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyri (more detail) 4 NA Homo sapiens
TAX015095
GO:0004370 molecular function glycerol kinase activity Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H(+). (more detail) 4 NA Homo sapiens
TAX015271
GO:0004619 molecular function phosphoglycerate mutase activity Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate. (more detail) 4 NA Homo sapiens
GEX000369
carotid artery stenosis carotid artery stenosis associated genes. PAGER constructed this gene set by grouping all genes whic (more detail) 4 NA Homo sapiens
TAX013212
GO:0000015 cellular component phosphopyruvate hydratase complex A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phosp (more detail) 4 NA Homo sapiens
TAX014975
GO:0004095 molecular function carnitine O palmitoyltransferase activity Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine. (more detail) 4 NA Homo sapiens
PEX002275
Hexokinase 1: Hexokinase Hexokinase (EC:2.7.1.1) contains two structurally similar domains represented by this family and Pfa (more detail) 4 NA Homo sapiens
POX000451
PathwayGeneSet, Reactome Genes associated with PathwayGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
POX000419
IsozymeGeneSet, KEGG Enzyme Genes associated with IsozymeGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
POX000396
PathwayGeneSet, HumanCyc Genes associated with PathwayGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
MOX014953
Genes associated with Computational Drug Signature Saframycin A Genes associated with Computational Drug Signature Saframycin A, curated by the Drug Signature Datab (more detail) 4 25990557 Homo sapiens
WIG001355
Imipramine/Desipramine Pathway, Pharmacokinetics Representation of the candidate genes involved in the metabolism of the tricyclic antidepressants im (more detail) 4 NA Homo sapiens
MEX000869
Genes associated with Approved Drug roflumilast Genes associated with Approved Drug roflumilast, curated by the Drug Signature Database (DSigDB). (more detail) 4 25990557 Homo sapiens
MOX003634
Genes associated with Computational Drug Signature adenosine 5' monophosphate Genes associated with Computational Drug Signature adenosine 5'-monophosphate, curated by the Drug S (more detail) 4 25990557 Homo sapiens
TAX015281
GO:0004634 molecular function phosphopyruvate hydratase activity Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O. (more detail) 4 NA Homo sapiens
PEX001157
PNP UDP 1: Phosphorylase superfamily Members of this family include: purine nucleoside phosphorylase (PNP) Uridine phosphorylase (UdRPase (more detail) 4 NA Homo sapiens
POX000446
PathwayGeneSet, HumanCyc Genes associated with PathwayGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
WAG000301
Glucose + ATP => glucose 6 phosphate + ADP (more detail) 4 NA Homo sapiens
MOX001933
Genes associated with Computational Drug Signature 2 NITROFLUORANTHENE Genes associated with Computational Drug Signature 2-NITROFLUORANTHENE, curated by the Drug Signatur (more detail) 4 25990557 Homo sapiens
MEX003961
Genes associated with Perturbagen Signature Prestwick 984 Genes associated with Perturbagen Signature Prestwick-984, curated by the Drug Signature Database (D (more detail) 4 25990557 Homo sapiens
TAX016429
GO:0006562 biological process proline catabolic process The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic (more detail) 4 NA Homo sapiens
POX000427
PathwayGeneSet, HumanCyc Genes associated with PathwayGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
POX000458
IsozymeGeneSet, KEGG Enzyme Genes associated with IsozymeGeneSet. PAGER constructed this gene-set from an Isozyme study (Bulent (more detail) 4 NA Homo sapiens
MEX000799
Genes associated with Approved Drug troleandomycin Genes associated with Approved Drug troleandomycin, curated by the Drug Signature Database (DSigDB). (more detail) 4 25990557 Homo sapiens
MOX003054
Genes associated with Computational Drug Signature Thiocoraline Genes associated with Computational Drug Signature Thiocoraline, curated by the Drug Signature Datab (more detail) 4 25990557 Homo sapiens
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Sorry, no more than 100 PAGs View PAGs' network View gene set network
Sorry, no more than 125 PAGs
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